Biochemistry and Molecular Biology

Research output

Research output per year 1975 1992 1996 1997 1998 1999 2000 2001 2002 2003 2004 2005 2006 2007 2008 2009 2010 2011 2012 2013 2014 2015 2016 2017 2018 2021

• 633 Article
• 41 Review article
• 11 Chapter
• 8 Comment/debate
• 9 More
  • 3 Letter
  • 2 Conference contribution
  • 2 Short survey
  • 1 Book
  • 1 Editorial

Research output per year

Research output per year

Search results

• 2011

  Eosinophils increase neuron branching in human and murine skin and in vitro

  Foster, E. L., Simpson, E. L., Fredrikson, L. J., Lee, J. J., Lee, N. A., Fryer, A. D. & Jacoby, D. B., 2011, In: PloS one. 6, 7, e22029.

  Research output: Contribution to journal › Article › peer-review

  • eosinophils 100%
  • Eosinophils 86%
  • branching 83%
  • neurons 74%
  • skin (animal) 68%
  56 Scopus citations

• Eosinophils regulate dendritic cells and Th2 pulmonary immune responses following allergen provocation

  Jacobsen, E. A., Zellner, K. R., Colbert, D., Lee, N. A. & Lee, J. J., Dec 1 2011, In: Journal of Immunology. 187, 11, p. 6059-6068 10 p.

  Research output: Contribution to journal › Article › peer-review

  • Eosinophils 100%
  • Allergens 97%
  • Dendritic Cells 92%
  • Lung 55%
  • T-Lymphocytes 31%
  89 Scopus citations

• Fluorescence polarization screening for allosteric small molecule ligands of the cholecystokinin receptor

  Harikumar, K. G., Cawston, E. E. & Miller, L. J., Aug 1 2011, In: Assay and Drug Development Technologies. 9, 4, p. 394-402 9 p.

  Research output: Contribution to journal › Article › peer-review

  • Cholecystokinin Receptors 100%
  • Fluorescence Polarization 94%
  • Polarization 52%
  • Ligands 49%
  • Benzodiazepines 47%
  8 Scopus citations

• Glutamine residues in Q-loops of multidrug resistance protein MRP1 contribute to ATP binding via interaction with metal cofactor

  Yang, R., Hou, Y. X., Campbell, C. A., Palaniyandi, K., Zhao, Q., Bordner, A. J. & Chang, X. B., Jul 2011, In: Biochimica et Biophysica Acta - Biomembranes. 1808, 7, p. 1790-1796 7 p.

  Research output: Contribution to journal › Article › peer-review

  • Glutamine Residue 100%
  • Subfamily B ATP Binding Cassette Transporter 97%
  • multidrug resistance-associated protein 1 96%
  • Glutamine 72%
  • Cofactor 62%
  9 Scopus citations

• Immunodetection of occult eosinophils in lung tissue biopsies may help predict survival in acute lung injury

  Willetts, L., Parker, K., Wesselius, L. J., Protheroe, C. A., Jaben, E., Graziano, P., Moqbel, R., Leslie, K. O., Lee, N. A. & Lee, J. J., Aug 26 2011, In: Respiratory Research. 12, 116.

  Research output: Contribution to journal › Article › peer-review

  • Acute Lung Injury 100%
  • Eosinophils 84%
  • Biopsy 53%
  • Survival 48%
  • Lung 47%
  24 Scopus citations

• Importance and regulation of the colonic mucus barrier in a mouse model of colitis

  Petersson, J., Schreiber, O., Hansson, G. C., Gendler, S. J., Velcich, A., Lundberg, J. O., Roos, S., Holm, L. & Phillipson, M., Feb 2011, In: American Journal of Physiology - Gastrointestinal and Liver Physiology. 300, 2, p. G327-G333

  Research output: Contribution to journal › Article › peer-review

  • Mucus 100%
  • Colitis 96%
  • Peptidoglycan 16%
  • Lipopolysaccharides 11%
  • Colon 10%
  200 Scopus citations

• Importance of each residue within secretin for receptor binding and biological activity

  Dong, M., Le, A., Te, J. A., Pinon, D. I., Bordner, A. J. & Miller, L. J., Apr 12 2011, In: Biochemistry. 50, 14, p. 2983-2993 11 p.

  Research output: Contribution to journal › Article › peer-review

  • secretin receptor 100%
  • Secretin 90%
  • Receptor Binding Activity 88%
  • Molecular Dynamics Simulation 26%
  • Alanine 23%
  21 Scopus citations

• Infection of H69AR cells with retroviral particles harboring interfering RNAi significantly reduced the multidrug resistance of these small cell lung cancer cells

  Palaniyandi, K., Zhao, Q. & Chang, X. B., Jun 10 2011, In: International Journal of Biochemistry and Molecular Biology. 2, 2, p. 155-167 13 p.

  Research output: Contribution to journal › Article › peer-review

  • Small Cell Lung Carcinoma 100%
  • Multiple Drug Resistance 94%
  • RNA Interference 86%
  • multidrug resistance-associated protein 1 78%
  • Antiapoptotic 64%
  6 Scopus citations

• Lactam constraints provide insights into the receptor-bound conformation of secretin and stabilize a receptor antagonist

  Dong, M., Te, J. A., Xu, X., Wang, J., Pinon, D. I., Storjohann, L., Bordner, A. J. & Miller, L. J., Sep 27 2011, In: Biochemistry. 50, 38, p. 8181-8192 12 p.

  Research output: Contribution to journal › Article › peer-review

  • Secretin 100%
  • Lactams 93%
  • Agent Interacting With Transmitter, Hormone or Drug Receptor 72%
  • Lactam 71%
  • Peptides 41%
  16 Scopus citations

• Local proliferation and mobilization of CCR3⁺ CD34⁺ eosinophil-lineage-committed cells in the lung

  Rådinger, M., Bossios, A., Sjöstrand, M., Lu, Y., Malmhäll, C., Dahlborn, A. K., Lee, J. J. & Lötvall, J., Jan 2011, In: Immunology. 132, 1, p. 144-154 11 p.

  Research output: Contribution to journal › Article › peer-review

  • Eosinophils 100%
  • Allergens 97%
  • Chemokine CCL24 89%
  • Lung 55%
  • Interleukin-5 38%
  25 Scopus citations

• Major basic protein from eosinophils and myeloperoxidase from neutrophils are required for protective immunity to Strongyloides stercoralis in mice

  O'Connell, A. E., Hess, J. A., Santiago, G. A., Nolan, T. J., Lok, J. B., Lee, J. J. & Abraham, D., Jul 2011, In: Infection and Immunity. 79, 7, p. 2770-2778 9 p.

  Research output: Contribution to journal › Article › peer-review

  • Eosinophil Major Basic Protein 100%
  • Strongyloides stercoralis 92%
  • myeloperoxidase 76%
  • eosinophils 66%
  • Eosinophils 57%
  70 Scopus citations

• MUC1 enhances invasiveness of pancreatic cancer cells by inducing epithelial to mesenchymal transition

  Roy, L. D., Sahraei, M., Subramani, D. B., Besmer, D., Nath, S., Tinder, T. L., Bajaj, E., Shanmugam, K., Lee, Y. Y., Hwang, S. I. L., Gendler, S. J. & Mukherjee, P., Mar 24 2011, In: Oncogene. 30, 12, p. 1449-1459 11 p.

  Research output: Contribution to journal › Article › peer-review

  • Epithelial-Mesenchymal Transition 100%
  • Pancreatic Neoplasms 91%
  • Cadherins 48%
  • Gastropoda 42%
  • Catenins 40%
  180 Scopus citations

• Pancreatic ductal adenocarcinoma mice lacking mucin 1 have a profound defect in tumor growth and metastasis

  Besmer, D. M., Curry, J. M., Roy, L. D., Tinder, T. L., Sahraei, M., Schettini, J., Hwang, S. I., Lee, Y. Y., Gendler, S. J. & Mukherjee, P., Jul 1 2011, In: Cancer research. 71, 13, p. 4432-4442 11 p.

  Research output: Contribution to journal › Article › peer-review

  • Mucin-1 100%
  • Adenocarcinoma 61%
  • Neoplasm Metastasis 48%
  • Growth 39%
  • Mitogen-Activated Protein Kinases 31%
  90 Scopus citations

• Recombinant plant-expressed tumour-associated MUC1 peptide is immunogenic and capable of breaking tolerance in MUC1.Tg mice

  Pinkhasov, J., Alvarez, M. L., Rigano, M. M., Piensook, K., Larios, D., Pabst, M., Grass, J., Mukherjee, P., Gendler, S. J., Walmsley, A. M. & Mason, H. S., Dec 2011, In: Plant Biotechnology Journal. 9, 9, p. 991-1001 11 p.

  Research output: Contribution to journal › Article › peer-review

  • Plant Tumors 100%
  • tandem repeat sequences 52%
  • MUC1 tandem repeat peptide 49%
  • neoplasms 43%
  • antigens 42%
  38 Scopus citations

• The identification of eosinophilic gastroenteritis in prednisone-dependent eosinophilic bronchitis and asthma

  Nair, P., Ochkur, S. I., Protheroe, C., Simms, E., Lee, N. A. & Lee, J. J., Mar 1 2011, In: Allergy, Asthma and Clinical Immunology. 7, 1, 4.

  Research output: Contribution to journal › Article › peer-review

  • Eosinophilic enteropathy 100%
  • Bronchitis 76%
  • Prednisone 66%
  • Asthma 50%
  • Hypereosinophilic Syndrome 46%
  9 Scopus citations

• The Pyk2 FERM regulates Pyk2 complex formation and phosphorylation

  Riggs, D., Yang, Z., Kloss, J. & Loftus, J. C., Jan 2011, In: Cellular Signalling. 23, 1, p. 288-296 9 p.

  Research output: Contribution to journal › Article › peer-review

  • FERM Domains 100%
  • Phosphorylation 42%
  • adhesion receptor 10%
  • Focal Adhesion Protein-Tyrosine Kinases 9%
  • Growth Factor Receptors 8%
  18 Scopus citations

• Update on clinical and immunological features of eosinophilic gastrointestinal diseases

  Masterson, J. C., Furuta, G. T. & Lee, J. J., Oct 2011, In: Current Opinion in Gastroenterology. 27, 6, p. 515-522 8 p.

  Research output: Contribution to journal › Review article › peer-review

  • Gastrointestinal Diseases 100%
  • Eosinophils 38%
  • Gastrointestinal Tract 23%
  • Chemokine CCL26 23%
  • thymic stromal lymphopoietin 20%
  29 Scopus citations

• What is the functional role of the thalidomide binding protein cereblon?

  Chang, X. B. & Keith Stewart, A., 2011, In: International Journal of Biochemistry and Molecular Biology. 2, 3, p. 287-294 8 p.

  Research output: Contribution to journal › Review article › peer-review

  • Thalidomide 100%
  • AMP-Activated Protein Kinases 77%
  • Carrier Proteins 54%
  • Chloride Channels 40%
  • Proteasome Endopeptidase Complex 33%
  49 Scopus citations
• 2010

  Airway eosinophilia in remission and progression of asthma: Accumulation with a fast decline of FEV₁

  Broekema, M., Volbeda, F., Timens, W., Dijkstra, A., Lee, N. A., Lee, J. J., Lodewijk, M. E., Postma, D. S., Hylkema, M. N. & Ten Hacken, N. H. T., Sep 2010, In: Respiratory Medicine. 104, 9, p. 1254-1262 9 p.

  Research output: Contribution to journal › Article › peer-review

  • Eosinophilia 100%
  • Sputum 79%
  • Airway Remodeling 75%
  • Asthma 71%
  • Eosinophils 55%
  50 Scopus citations

• Altered eosinophil profile in mice with ST6Gal-1 deficiency: An additional role for ST6Gal-1 generated by the P1 promoter in regulating allergic inflammation

  Nasirikenari, M., Chandrasekaran, E. V., Matta, K. L., Segal, B. H., Bogner, P. N., Lugade, A. A., Thanavala, Y., Lee, J. J. & Lau, J. T. Y., Mar 2010, In: Journal of Leukocyte Biology. 87, 3, p. 457-466 10 p.

  Research output: Contribution to journal › Article › peer-review

  • beta-D-galactoside alpha 2-6-sialyltransferase 100%
  • Eosinophils 56%
  • Inflammation 34%
  • Sialyltransferases 5%
  • Pulmonary Eosinophilia 5%
  28 Scopus citations

• Analysis of a cholera toxin B subunit (CTB) and human mucin 1 (MUC1) conjugate protein in a MUC1-tolerant mouse model

  Pinkhasov, J., Alvarez, M. L., Pathangey, L. B., Tinder, T. L., Mason, H. S., Walmsley, A. M., Gendler, S. J. & Mukherjee, P., Dec 2010, In: Cancer Immunology, Immunotherapy. 59, 12, p. 1801-1811 11 p.

  Research output: Contribution to journal › Article › peer-review

  • Mucin-1 100%
  • Cholera Toxin 92%
  • Proteins 28%
  • Oligodeoxyribonucleotides 25%
  • Autoantigens 23%
  12 Scopus citations

• Dimeric arrangement of the parathyroid hormone receptor and a structural mechanism for ligand-induced dissociation

  Pioszak, A. A., Harikumar, K. G., Parker, N. R., Miller, L. J. & Xu, H. E., Apr 16 2010, In: Journal of Biological Chemistry. 285, 16, p. 12435-12444 10 p.

  Research output: Contribution to journal › Article › peer-review

  • Parathyroid Hormone Receptor Type 1 100%
  • Parathyroid Hormone 96%
  • Parathyroid Hormone-Related Protein 59%
  • Protein Subunits 51%
  • Dissociation 47%
  49 Scopus citations

• Elucidation of the active conformation of the amino terminus of receptor-bound secretin using intramolecular disulfide bond constraints

  Dong, M., Pinon, D. I., Bordner, A. J. & Miller, L. J., Oct 2010, In: Bioorganic and Medicinal Chemistry Letters. 20, 20, p. 6040-6044 5 p.

  Research output: Contribution to journal › Article › peer-review

  • secretin receptor 100%
  • Secretin 90%
  • Disulfides 62%
  • Disulfide 48%
  • Peptides 37%
  5 Scopus citations

• Eosinophils in health and disease: The LIAR hypothesis

  Lee, J. J., Jacobsen, E. A., McGarry, M. P., Schleimer, R. P. & Lee, N. A., Apr 2010, In: Clinical and Experimental Allergy. 40, 4, p. 563-575 13 p.

  Research output: Contribution to journal › Comment/debate › peer-review

  • Eosinophils 100%
  • Health 50%
  • Textbooks 12%
  • Helminths 12%
  • Entropy 12%
  199 Scopus citations

• Importance of lipid-exposed residues in transmembrane segment four for family B calcitonin receptor homo-dimerization

  Harikumar, K. G., Ball, A. M., Sexton, P. M. & Miller, L. J., Sep 2010, In: Regulatory Peptides. 164, 2-3, p. 113-119 7 p.

  Research output: Contribution to journal › Article › peer-review

  • Calcitonin Receptors 100%
  • Calcitonin 94%
  • Dimerization 73%
  • Energy Transfer 64%
  • Bioluminescence 48%
  22 Scopus citations

• Longevity and age-related pathology of mice deficient in pregnancy-associated plasma protein-a

  Conover, C. A., Bale, L. K., Mader, J. R., Mason, M. A., Keenan, K. P. & Marler, R. J., Jun 2010, In: Journals of Gerontology - Series A Biological Sciences and Medical Sciences. 65 A, 6, p. 590-599 10 p.

  Research output: Contribution to journal › Article › peer-review

  • Pregnancy-Associated Plasma Protein-A 100%
  • Longevity 62%
  • Blood Proteins 61%
  • Knockout Mice 53%
  • Pathology 44%
  64 Scopus citations

• Modulation of cell surface expression of nonactivated cholecystokinin receptors using bivalent ligand-induced internalization

  Harikumar, K. G., Akgün, E., Portoghese, P. S. & Miller, L. J., Apr 8 2010, In: Journal of Medicinal Chemistry. 53, 7, p. 2836-2842 7 p.

  Research output: Contribution to journal › Article › peer-review

  • Cholecystokinin Receptors 100%
  • Cholecystokinin B Receptor Antagonist 50%
  • Ligands 49%
  • Cholecystokinin B Receptor 28%
  • Agent Interacting With Transmitter, Hormone or Drug Receptor 22%
  14 Scopus citations

• Molecular mechanism of ATP-dependent solute transport by multidrug resistance-associated protein 1.

  Chang, X. B., 2010, In: Methods in molecular biology (Clifton, N.J.). 596, p. 223-249 27 p.

  Research output: Contribution to journal › Review article › peer-review

  • multidrug resistance-associated protein 1 100%
  • Adenosine Triphosphate 55%
  • Multiple Drug Resistance 37%
  • Neoplasms 22%
  • ATP-Binding Cassette Transporters 21%
  27 Scopus citations

• MultiRTA: A simple yet reliable method for predicting peptide binding affinities for multiple class II MHC allotypes

  Bordner, A. J. & Mittelmann, H. D., Sep 24 2010, In: BMC bioinformatics. 11, 482.

  Research output: Contribution to journal › Article › peer-review

  • Peptides 100%
  • Affine transformation 79%
  • Kd 53%
  • Prediction 43%
  • HLA-DP Antigens 41%
  32 Scopus citations

• Murine lung eosinophil activation and chemokine production in allergic airway inflammation

  Rose, C. E., Lannigan, J. A., Kim, P., Lee, J. J., Fu, S. M. & Sung, S. S. J., 2010, In: Cellular and Molecular Immunology. 7, 5, p. 361-374 14 p.

  Research output: Contribution to journal › Article › peer-review

  • Eosinophils 100%
  • Chemokines 97%
  • Inflammation 60%
  • Lung 55%
  • Macrophage Inflammatory Proteins 42%
  46 Scopus citations

• Novel model of T_H2-polarized chronic ileitis: The SAMPl mouse

  McNamee, E. N., Wermers, J. D., Masterson, J. C., Collins, C. B., Matthew, D. P., Lebsack, B. A., Fillon, S., Robinson, Z. D., Grenawalt, J., Lee, J. J., Jedlicka, P., Furuta, G. T. & Rivera-Nieves, J., 2010, In: Inflammatory bowel diseases. 16, 5, p. 743-752 10 p.

  Research output: Contribution to journal › Article › peer-review

  • Ileitis 100%
  • Ileum 33%
  • Crohn Disease 31%
  • 4-(4-sulfophenylazo)-2-mercuriphenol 30%
  • Cytokines 30%
  26 Scopus citations

• Orientation-dependent backbone-only residue pair scoring functions for fixed backbone protein design

  Bordner, A. J., Apr 16 2010, In: BMC bioinformatics. 11, 192.

  Research output: Contribution to journal › Article › peer-review

  • Backbone 100%
  • Scoring 93%
  • Protein 81%
  • Proteins 71%
  • Dependent 51%
  5 Scopus citations

• Prediction of the binding affinities of peptides to class II MHC using a regularized thermodynamic model

  Bordner, A. J. & Mittelmann, H. D., Jan 20 2010, In: BMC bioinformatics. 11, 41.

  Research output: Contribution to journal › Article › peer-review

  • Peptides 100%
  • Thermodynamics 86%
  • Affine transformation 79%
  • Prediction 56%
  • Kd 53%
  24 Scopus citations

• Refinement of the pharmacophore of an agonist ligand of the secretin receptor using conformationally constrained cyclic hexapeptides

  Dong, M., Narang, P., Pinon, D. I., Bordner, A. J. & Miller, L. J., Jun 2010, In: Peptides. 31, 6, p. 1094-1098 5 p.

  Research output: Contribution to journal › Article › peer-review

  • secretin receptor 100%
  • Secretin 90%
  • Agonist 56%
  • Ligands 41%
  • Cyclic Amino Acids 37%
  3 Scopus citations

• Reprogrammed FoxP3⁺ T regulatory cells become IL-17⁺ antigen-specific autoimmune effectors in vitro and in vivo (The Journal of Immunology (2008) 181, (3137-3147))

  Radhakrishnan, S., Cabrera, R., Schenk, E. L., Nava-Parada, P., Bell, M. P., Van Keulen, V. P., Marler, R. J., Felts, S. J. & Pease, L. R., Jun 1 2010, In: Journal of Immunology. 184, 11, p. 6556 1 p.

  Research output: Contribution to journal › Comment/debate › peer-review
  5 Scopus citations

• Secretin Receptor Dimerization: A Possible Functionally Important Paradigm for Family B G Protein-Coupled Receptors

  Harikumar, K. G., Dong, M. & Miller, L. J., Jul 15 2010, GPCR Molecular Pharmacology and Drug Targeting: Shifting Paradigms and New Directions. John Wiley and Sons, p. 138-164 27 p.

  Research output: Chapter in Book/Report/Conference proceeding › Chapter
  3 Scopus citations

• Structural conservation in band 4.1, ezrin, radixin, moesin (FERM) domains as a guide to identify inhibitors of the proline-rich tyrosine kinase 2

  Meurice, N., Wang, L., Lipinski, C. A., Yang, Z., Hulme, C. & Loftus, J. C., 2010, In: Journal of Medicinal Chemistry. 53, 2, p. 669-677 9 p.

  Research output: Contribution to journal › Article › peer-review

  • FERM Domains 100%
  • Focal Adhesion Kinase 2 98%
  • Functional Site 87%
  • Site-Directed Mutagenesis 63%
  • Tyrosine 55%
  10 Scopus citations

• Targeting Pyk2 for therapeutic intervention

  Lipinski, C. A. & Loftus, J. C., Jan 2010, In: Expert opinion on therapeutic targets. 14, 1, p. 95-108 14 p.

  Research output: Contribution to journal › Review article › peer-review

  • Focal Adhesion Protein-Tyrosine Kinases 100%
  • Tyrosine 73%
  • Protein-Tyrosine Kinases 48%
  • Effector 43%
  • Cell Movement 21%
  73 Scopus citations

• Towards universal structure-based prediction of class II MHC epitopes for diverse allotypes

  Bordner, A. J., 2010, In: PloS one. 5, 12, e14383.

  Research output: Contribution to journal › Article › peer-review

  • Epitope 100%
  • epitopes 94%
  • Epitopes 84%
  • peptides 66%
  • prediction 66%
  18 Scopus citations

• TROY (TNFRSF19) is overexpressed in advanced glial tumors and promotes glioblastoma cell invasion via Pyk2-Rac1 signaling

  Paulino, V. M., Yang, Z., Kloss, J., Ennis, M. J., Armstrong, B. A., Loftus, J. C. & Tran, N. L., Nov 2010, In: Molecular Cancer Research. 8, 11, p. 1558-1567 10 p.

  Research output: Contribution to journal › Article › peer-review

  • Glioblastoma 100%
  • Glioma 93%
  • Neuroglia 89%
  • Tumor Necrosis Factors 32%
  • Neoplasms 32%
  47 Scopus citations
• 2009

  A Novel Histologic Scoring System to Evaluate Mucosal Biopsies From Patients With Eosinophilic Esophagitis

  Protheroe, C., Woodruff, S. A., de Petris, G., Mukkada, V., Ochkur, S. I., Janarthanan, S., Lewis, J. C., Pasha, S., Lunsford, T., Harris, L., Sharma, V. K., McGarry, M. P., Lee, N. A., Furuta, G. T. & Lee, J. J., Jul 2009, In: Clinical Gastroenterology and Hepatology. 7, 7, p. 749-755.e11

  Research output: Contribution to journal › Article › peer-review

  • Eosinophilic Esophagitis 100%
  • Eosinophilia 48%
  • Gastroesophageal Reflux 45%
  • Biopsy 42%
  • Eosinophil Peroxidase 27%
  142 Scopus citations

• Application of fluorescence resonance energy transfer techniques to establish ligand-receptor orientation.

  Harikumar, K. G. & Miller, L. J., 2009, In: Methods in molecular biology (Clifton, N.J.). 552, p. 293-304 12 p.

  Research output: Contribution to journal › Article › peer-review

  • Fluorescence Resonance Energy Transfer 100%
  • Fluorescence 61%
  • Ligands 52%
  • alexa 568 38%
  • methanethiosulfonate 32%
  2 Scopus citations

• Differential effects of Pyk2 and FAK on the hypertrophic response of cardiac myocytes

  Menashi, E. B. & Loftus, J. C., Aug 2009, In: Cell and Tissue Research. 337, 2, p. 243-255 13 p.

  Research output: Contribution to journal › Article › peer-review

  • Focal Adhesion Kinase 2 100%
  • Focal Adhesion Protein-Tyrosine Kinases 76%
  • Cardiac Myocytes 57%
  • Atrial Natriuretic Factor 34%
  • Phenylephrine 22%
  7 Scopus citations

• Effects of putative catalytic base mutation E211Q on ABCG2-mediated methotrexate transport

  Hou, Y. X., Li, C. Z., Palaniyandi, K., Magtibay, P. M., Homolya, L., Sarkadi, B. & Chang, X. B., 2009, In: Biochemistry. 48, 38, p. 9122-9131 10 p.

  Research output: Contribution to journal › Article › peer-review

  • Methotrexate 100%
  • Homodimer 68%
  • Heterodimer 68%
  • Mutation 67%
  • Adenosine Triphosphate 62%
  9 Scopus citations

• Eosinophil deficiency compromises parasite survival in chronic nematode infection

  Fabre, V., Beiting, D. P., Bliss, S. K., Gebreselassie, N. G., Gagliardo, L. F., Lee, N. A., Lee, J. J. & Appleton, J. A., Feb 1 2009, In: Journal of Immunology. 182, 3, p. 1577-1583 7 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Nematode Infections 100%
  • Eosinophils 63%
  • Parasites 54%
  • Helminths 35%
  • Trichinella spiralis 32%
  115 Scopus citations

• Eosinophils oxidize damage-associated molecular pattern molecules derived from stressed cells

  Lotfi, R., Herzog, G. I., DeMarco, R. A., Beer-Stolz, D., Lee, J. J., Rubartelli, A., Schrezenmeier, H. & Lotze, M. T., Oct 15 2009, In: Journal of Immunology. 183, 8, p. 5023-5031 9 p.

  Research output: Contribution to journal › Article › peer-review

  • Alarmins 100%
  • Eosinophils 64%
  • Receptor for Advanced Glycation End Products 19%
  • Eosinophil Peroxidase 11%
  • Necrosis 11%
  76 Scopus citations

• Eosinophils utilize multiple chemokine receptors for chemotaxis to the parasitic nematode strongyloides stercoralis

  Stein, L. H., Redding, K. M., Lee, J. J., Nolan, T. J., Schad, G. A., Lok, J. B. & Abraham, D., Oct 2009, In: Journal of Innate Immunity. 1, 6, p. 618-630 13 p.

  Research output: Contribution to journal › Article › peer-review

  • Strongyloides stercoralis 100%
  • Chemokine Receptors 77%
  • Chemotaxis 74%
  • Eosinophils 67%
  • Parasites 51%
  26 Scopus citations

• Expression of human MUC1 during early pregnancy in the human MUC1 transgenic mouse model

  Dharmaraj, N., Gendler, S. J. & Carson, D. D., 2009, In: Biology of Reproduction. 81, 6, p. 1182-1188 7 p.

  Research output: Contribution to journal › Article › peer-review

  • Transgenic Mice 100%
  • Pregnancy 67%
  • Uterus 34%
  • Epithelium 28%
  • Embryonic Structures 20%
  21 Scopus citations

• Functional importance of a structurally distinct homodimeric complex of the family B G protein-coupled secretin receptor

  Gao, F., Harikumar, K. G., Dong, M., Lam, P. C. H., Sexton, P. M., Christopoulos, A., Bordner, A., Abagyan, R. & Miller, L. J., Aug 2009, In: Molecular pharmacology. 76, 2, p. 264-274 11 p.

  Research output: Contribution to journal › Article › peer-review

  • secretin receptor 100%
  • Energy Transfer 77%
  • G-Protein-Coupled Receptors 59%
  • Cysteine 55%
  • Guanine Nucleotides 48%
  43 Scopus citations

• Induced association of μ opioid (MOP) and type 2 cholecystokinin (CCK ₂) receptors by novel bivalent ligands

  Zheng, Y., Akgiin, E., Harikumar, K. G., Hopson, J., Powers, M. D., Lunzer, M. M., Miller, L. J. & Portoghese, P. S., Jan 22 2009, In: Journal of Medicinal Chemistry. 52, 2, p. 247-258 12 p.

  Research output: Contribution to journal › Article › peer-review

  • Heterodimerization 100%
  • Cholecystokinin B Receptor 97%
  • Cholecystokinin Receptors 96%
  • Bioluminescence 80%
  • Fluorescence Resonance Energy Transfer 66%
  49 Scopus citations