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Identifying genes and Pathways that impact Tau Toxicity in FTD

Dickson, D. W. & Petrucelli, L.

National Institutes of Health

9/30/166/30/21

Project: Research projectSpecialized Center--Cooperative Agreements

Tauopathies
Genes
Progressive Supranuclear Palsy
Parkinsonian Disorders
Dementia
Elasticity Imaging Techniques
Transplants
Liver
Tissue
Ultrasonics
Growth Differentiation Factors
Proteins
Plasminogen Activator Inhibitor 2
Motor Activity
International Classification of Diseases

The Mayo GBM Xenograft National Resource

Sarkaria, J. N.

National Institutes of Health

9/30/165/31/20

Project: Research projectResource-Related Research Projects

Glioblastoma
Heterografts
Neoplasms
Tumors
Atlases
Synucleins
Parkinson Disease
Pathology
Brain
Nuclear Envelope

Metadata applications on informed content to facilitate biorepository data regulation and sharing

National Institutes of Health

9/28/167/31/19

Project: Research projectResearch Project--Cooperative Agreements

Information Dissemination
Metadata
Ontology
Consent Forms
Informed Consent

Pathobiology of Liver Injury

Malhi, H. M.

National Institutes of Health

9/23/168/31/21

Project: Research projectResearch Project

Macrophages
Liver
Wounds and Injuries
Ceramides
Sphingosine
Heart Failure
Caregivers
Social Support
Health
Spouses

Tools for standardizing clinical research metadata using HL7 FHIR

Jiang, G. D.

National Institutes of Health

9/15/168/31/19

Project: Research projectResearch Project--Cooperative Agreements

Biomedical Research
Delivery of Health Care
Metadata
Interoperability
Semantics

Mechanisms of Epigenetic inheritance

Zhang, Z. H.

National Institutes of Health

9/1/167/31/21

Project: Research projectOutstanding Investigator Award

Nucleosomes
DNA Replication
Epigenomics
Histones
Yeasts
Pathology
White Matter
Cognition
Alzheimer Disease
Anisotropy

Zinc-targeting inhibitors of insulin-degrading enzyme

National Institutes of Health

9/1/167/31/21

Project: Research projectResearch Project

Insulysin
Zinc
Enzyme Inhibitors
Metals
Insulin

Advancing Cancer Pharmacoepidemiology Research Through EHRs and Informatics

Yang, P.

National Institutes of Health

9/1/168/31/21

Project: Research projectResource-Related Research Projects--Cooperative Agreements

Pharmacoepidemiology
Electronic Health Records
Neoplasms
Natural Language Processing
Pharmacovigilance
Mengovirus
Oncolytic Virotherapy
Replicon
Genome
Genes

MSK SPORE in Lymphoma

National Institutes of Health

8/30/167/31/21

Project: Research projectSpecialized Center

Lymphoma
Lymphoma, Large B-Cell, Diffuse
Biological Markers
Clinical Trials
Tissue Distribution

MIT/Mayo Physical Sciences Center for Drug Distribution and Efficacy in Brain Tumors

Swanson, K. & Sarkaria, J. N.

National Institutes of Health

8/29/167/31/21

Project: Research projectSpecialized Center--Cooperative Agreements

Tumors
Neoplasms
Imaging techniques
Brain Neoplasms
Brain
Pancreatic Neoplasms
Melanoma
Phenotype
Mutation
Modifier Genes
Liver Cirrhosis
Lung
Fibroblasts
Chemical activation
Liver
Health
Sirolimus
Dehydration
Chronic Disease
Anesthesia

Translational Molecular and Cellular Imaging Technologies for Prostate Tumor Pathology

Cheville, J.

National Institutes of Health

8/4/167/31/19

Project: Research projectExploratory/Developmental Grants Phase II

Molecular Imaging
Prostate
Pathology
Technology
Neoplasms
Cocaine-Related Disorders
Hydrolases
Genes
Cocaine
Telecommunications

Regulation of Copper Homeostasis by COMMD proteins

Billadeau, D. D. & Burstein, E.

National Institutes of Health

8/1/165/31/21

Project: Research projectResearch Project

Copper
Homeostasis
Proteins
Endosomes
Intestinal Absorption
Reflex
Anoxia
Sleep Apnea Syndromes
Hypertension
Baroreflex

REAL-TIME FEEDBACK TO IMPROVE COLONOSCOPY

De Groen, P. C.

National Institutes of Health

8/1/165/31/20

Project: Research projectResearch Project

Colonoscopy
Feedback
Endoscopy
Colorectal Neoplasms
Neoplasms
Wounds and Injuries
Neurologic Manifestations
Nervous System Diseases
Brain Injuries
Hospital Emergency Service

Molecular Oncology Training Program

Schwartz, G. L. & Emerson, S.

National Institutes of Health

7/18/166/30/21

Project: Research projectInstitutional National Research Service Award

Education
Neoplasms
Physicians
Medical Oncology
Translational Medical Research

Pharmacogenomics of Treatment Outcomes in Alcohol Use Disorders

Biernacka, J. M. & Karpyak, V.

National Institutes of Health

7/15/166/30/18

Project: Research projectExploratory/Developmental Grants

Naltrexone
Pharmacogenetics
Alcohols
Genome
Genes

Mayo Clinic Prospective Resource for Biomarker Validation and Early Detection of Pancreatic Cancer

Petersen, G. M. & Zaret, K. S.

National Institutes of Health

7/15/166/30/21

Project: Research projectResearch Project--Cooperative Agreements

Pancreatic Neoplasms
Early Detection of Cancer
Biological Markers
Adenocarcinoma
Genetic Markers

Genetic Epidemiology of non-Hodgkin Lymphoma

Cerhan, J. R.

National Institutes of Health

7/8/165/31/21

Project: Research projectResearch Project

Follicular Lymphoma
Molecular Epidemiology
Non-Hodgkin's Lymphoma
Genome-Wide Association Study
Single Nucleotide Polymorphism

Targeting MMP-9 for breast cancer therapy (R21 CA205471 Resubmission)

Radisky, E. S.

National Institutes of Health

7/1/166/30/18

Project: Research projectExploratory/Developmental Grants

Matrix Metalloproteinase 9
Breast Neoplasms
Matrix Metalloproteinase Inhibitors
Neoplasms
Proteins

CD8 T cell mediated disruption of Blood Brain Barrier Tight Junctions

Johnson, A. J.

National Institutes of Health

7/1/166/30/17

Project: Research projectHigh Priority, Short Term Project Award

Tight Junctions
Blood-Brain Barrier
Intercellular Signaling Peptides and Proteins
T-Lymphocytes
Capillary Permeability
Nicotinic Receptors
Calcium
Divalent Cations
Positive ions
Molecules
Adenocarcinoma
Lung
Neoplastic Stem Cells
Phenotype
Neoplasms

Localized measurement and mapping of tissue nonlinear elasticity

Alizad, A. & Fatemi, M.

National Institutes of Health

7/1/166/30/18

Project: Research projectExploratory/Developmental Grants

Elasticity
Tissue
Elasticity Imaging Techniques
Acoustics
Radiation
Plasma Cells
Bone Marrow
Isoantibodies
In Vitro Techniques
Organ Transplantation

Comparative Effectiveness of Biofeedback, Sacral Nerve Stimulation, and Injectable Bulking Agents for Treatment of Fecal Incontinence

Bharucha, A. E., Whitehead, W., Rao, S., Lowry, A. & Gantz, M.

National Institutes of Health

6/20/165/31/18

Project: Research projectClinical Planning Grant Cooperative Agreement

Fecal Incontinence
Safety
Electric Stimulation
Quality of Life
National Institute of Diabetes and Digestive and Kidney Diseases (U.S.)

Measles virus airway epithelium entry, and rapid cell-to-cell spread

Cattaneo, R. & Sinn, P.

National Institutes of Health

6/7/165/31/18

Project: Research projectExploratory/Developmental Grants

Measles virus
Epithelium
Viruses
Myeloid Cells
Infection
Telomere
Colorectal Neoplasms
Phenotype
Neoplasms
Leukocytes

Immune Contribution to Brain Atrophy

Johnson, A. J.

National Institutes of Health

6/1/165/31/18

Project: Research projectExploratory/Developmental Grants

Atrophy
Brain
T-Lymphocytes
Transgenic Mice
Infection
Sodium Iodide
Symporters
Single-Photon Emission-Computed Tomography
Radiometry
Measles virus

Development of Intrasaccular Flow Disrupters for Small and Ruptured Aneurysms

Kallmes, D. F. & Patterson, W. R.

National Institutes of Health

6/1/165/31/18

Project: Research projectSmall Business Innovation Research Grants (SBIR) - Phase II

Ruptured Aneurysm
Equipment and Supplies
Aneurysm
Catheters
United Arab Emirates

Disappearance of rifampin resistance in MRSA foreign body osteomyelitis

Patel, R.

National Institutes of Health

6/1/165/31/18

Project: Research projectExploratory/Developmental Grants

Osteomyelitis
Rifampin
Methicillin-Resistant Staphylococcus aureus
Foreign Bodies
Bacteria

Precision Medicine Initiative Cohort Program Biobank

Thibodeau, S. N. & Cicek, M.

National Institutes of Health

6/1/165/31/21

Project: Research projectResource-Related Research Projects--Cooperative Agreements

Medicine
Laboratory Automation
Committee Membership
Confidentiality
Robotics

Mechanisms Regulating Human NK Cell Cytotoxicity

Billadeau, D. D.

National Institutes of Health

5/17/164/30/21

Project: Research projectResearch Project

Natural Killer Cells
Cytokinesis
Actins
Septins
Microtubule-Organizing Center

Clinical Implementation of Clopidogrel Pharmacogenetics: The TAILOR-PCI Trial - DCC

Bailey, K. R.

National Institutes of Health

5/15/163/31/20

Project: Research projectResearch Project--Cooperative Agreements

Pharmacogenetics
Percutaneous Coronary Intervention
Cytochrome P-450 CYP2C19
Alleles
Registries
Primary Progressive Aphasia
Neuroimaging
Positron-Emission Tomography
Brain
Neuropsychology

Postdoctoral Training Program for Research on Aging

Conover, C. A.

National Institutes of Health

5/1/164/30/18

Project: Research projectInstitutional National Research Service Award

Biomedical Research
Education
Mentors
Cost of Illness
Translational Medical Research
AMP-Activated Protein Kinases
Carcinogenesis
Neoplasms
Breast Neoplasms
Metformin

Endothelial function of amyloid precursor protein

Katusic, Z. S.

National Institutes of Health

4/11/162/29/20

Project: Research projectResearch Project

Amyloid beta-Protein Precursor
Endothelium
Blood Vessels
Endothelial Cells
Brain