Biochemistry and Molecular Biology

Research Output

2001

Temporal association between airway hyperresponsiveness and airway eosinophilia in ovalbumin-sensitized mice

Tomkinson, A., Cieslewicz, G., Duez, C., Larson, K. A., Lee, J. J. & Gelfand, E. W., Jan 1 2001, In : American journal of respiratory and critical care medicine. 163, 3 I, p. 721-730 10 p.

Research output: Contribution to journalArticle

143 Scopus citations

Transgenic MUC1 Interacts with Epidermal Growth Factor Receptor and Correlates with Mitogen-activated Protein Kinase Activation in the Mouse Mammary Gland

Schroeder, J. A., Thompson, M. C., Gardner, M. M. & Gendler, S. J., Apr 20 2001, In : Journal of Biological Chemistry. 276, 16, p. 13057-13064 8 p.

Research output: Contribution to journalArticle

270 Scopus citations

Vaccination with allogeneic dendritic cells fused to carcinoma cells induces antitumor immunity in MUC1 transgenic mice

Tanaka, Y., Koido, S., Chen, D., Gendler, S. J., Kufe, D. & Gong, J., Jan 1 2001, In : Clinical Immunology. 101, 2, p. 192-200 9 p.

Research output: Contribution to journalArticle

57 Scopus citations
2000

Adenoma-specific alterations of protein kinase C isozyme expression in Apc(MIN) mice

Klein, I. K., Ritland, S. R., Burgart, L. J., Ziesmer, S. C., Roche, P. C., Gendler, S. J. & Karnes, W. E., Apr 15 2000, In : Cancer research. 60, 8, p. 2077-2080 4 p.

Research output: Contribution to journalArticle

23 Scopus citations

Allosteric interactions between the two non-equivalent nucleotide binding domains of multidrug resistance protein MRP1

Hou, Y. X., Cui, L., Riordan, J. R. & Chang, X. B., Jul 7 2000, In : Journal of Biological Chemistry. 275, 27, p. 20280-20287 8 p.

Research output: Contribution to journalArticle

131 Scopus citations

A novel CFTR disease-associated mutation causes addition of an extra N-linked oligosaccharide

Hämmerle, M. M., Aleksandrov, A. A., Chang, X. B. & Riordan, J. R., Jan 1 2000, In : Glycoconjugate Journal. 17, 11, p. 807-813 7 p.

Research output: Contribution to journalArticle

9 Scopus citations

CD23 exhibits negative regulatory effects on allergic sensitization and airway hyperresponsiveness

Haczku, A., Takeda, K., Hamelmann, E., Loader, J., Joetham, A., Redai, I., Irvin, C. G., Lee, J. J., Kikutani, H., Conrad, D. & Gelfand, E. W., 2000, In : American journal of respiratory and critical care medicine. 161, 3 I, p. 952-960 9 p.

Research output: Contribution to journalArticle

65 Scopus citations

Differential recognition of snake venom proteins expressing specific Arg-Gly-Asp (RGD) sequence motifs by wild-type and variant integrin αIIbβ3: Further evidence for distinct sites of RGD ligand recognition exhibiting negative allostery

Rahman, S., Flynn, G., Aitken, A., Patel, Y., Hussain, F., Lu, X., Loftus, J. C., French, D., Wijelath, E., Strand, K. & Savidge, G. F., Feb 1 2000, In : Biochemical Journal. 345, 3, p. 701-709 9 p.

Research output: Contribution to journalArticle

16 Scopus citations

Effect of alcohols on G-protein coupling of serotonin(1A) receptors from bovine hippocampus

Harikumar, K. G. & Chattopadhyay, A., Aug 1 2000, In : Brain Research Bulletin. 52, 6, p. 597-601 5 p.

Research output: Contribution to journalArticle

17 Scopus citations

Eosinophil major basic protein-1 does not contribute to allergen-induced airway pathologies in mouse models of asthma

Denzler, K. L., Farmer, S. C., Crosby, J. R., Borchers, M., Cieslewicz, G., Larson, K. A., Cormier-Regard, S., Lee, N. A. & Lee, J. J., Nov 15 2000, In : Journal of Immunology. 165, 10, p. 5509-5517 9 p.

Research output: Contribution to journalArticle

Open Access
102 Scopus citations

Eosinophils are cellular targets of the novel uteroplacental heparin-binding cytokine decidual/trophoblast prolactin-related protein

Wang, D., Ishimura, R., Walia, D. S., Muller, H., Dai, G., Hunt, J. S., Lee, N. A., Lee, J. J. & Soares, M. J., Jan 1 2000, In : Journal of Endocrinology. 167, 1, p. 15-28 14 p.

Research output: Contribution to journalArticle

Open Access
25 Scopus citations

Identification of a new murine eosinophil major basic protein (mMBP) gene: Cloning and characterization of mMBP-2

Macias, M. P., Welch, K. C., Denzler, K. L., Larson, K. A., Lee, N. A. & Lee, J. J., Jan 1 2000, In : Journal of Leukocyte Biology. 67, 4, p. 567-576 10 p.

Research output: Contribution to journalArticle

24 Scopus citations

Immobilization of silver ions onto paramagnetic particles for binding and release of a biotin-labeled oligonucleotide

Ramírez-Vick, J. E., García, A. A. & Lee, J., Feb 16 2000, In : Reactive and Functional Polymers. 43, 1, p. 53-62 10 p.

Research output: Contribution to journalArticle

5 Scopus citations

Induction of antitumor immunity by vaccination of dendritic cells transfected with MUC1 RNA

Koido, S., Kashiwaba, M., Chen, D., Gendler, S., Kufe, D. & Gong, J., Nov 15 2000, In : Journal of Immunology. 165, 10, p. 5713-5719 7 p.

Research output: Contribution to journalArticle

Open Access
141 Scopus citations

Inhibition of epidermal growth factor receptor tyrosine kinase fails to suppress adenoma formation in Apc(Min) mice but induces duodenal injury

Ritland, S. R., Gendler, S. J., Burgart, L. J., Fry, D. W., Nelson, J. M., Bridges, A. J., Andress, L. & Karnes, J., Sep 1 2000, In : Cancer research. 60, 17, p. 4678-4681 4 p.

Research output: Contribution to journalArticle

16 Scopus citations

Ligand binding to integrins

Plow, E. F., Haas, T. A., Zhang, L., Loftus, J. & Smith, J. W., Jul 21 2000, In : Journal of Biological Chemistry. 275, 29, p. 21785-21788 4 p.

Research output: Contribution to journalShort survey

1010 Scopus citations

Mercury induces regional and cell-specific stress protein expression in rat kidney

Goering, P. L., Fisher, B. R., Noren, B. T., Papaconstantinou, A., Rojko, J. L. & Marler, R. J., Feb 28 2000, In : Toxicological Sciences. 53, 2, p. 447-457 11 p.

Research output: Contribution to journalArticle

71 Scopus citations

Mice with spontaneous pancreatic cancer naturally develop MUC-1-specific CTLs that eradicate tumors when adoptively transferred

Mukherjee, P., Ginardi, A. R., Madsen, C. S., Sterner, C. J., Adriance, M. C., Tevethia, M. J. & Gendler, S. J., Sep 15 2000, In : Journal of Immunology. 165, 6, p. 3451-3460 10 p.

Research output: Contribution to journalArticle

Open Access
75 Scopus citations

MUC1/episialin: A critical barrier in the female reproductive tract

Desouza, M. M., Surveyor, G. A., Price, R. E., Julian, J., Kardon, R., Zhou, X., Gendler, S., Hilkens, J. & Carson, D. D., Jan 1 2000, In : Journal of Reproductive Immunology. 45, 2, p. 127-158 32 p.

Research output: Contribution to journalArticle

127 Scopus citations

Multidrug resistance protein MRP1 reconstituted into lipid vesicles: Secondary structure and nucleotide-induced tertiary structure changes

Manciu, L., Chang, X. B., Riordan, J. R. & Ruysschaert, J. M., Oct 24 2000, In : Biochemistry. 39, 42, p. 13026-13033 8 p.

Research output: Contribution to journalArticle

26 Scopus citations

Role of disulfides and sulfhydryl groups in agonist and antagonist binding in serotonin(1A) receptors from bovine hippocampus

Harikumar, K. G., John, P. T. & Chattopadhyay, A., Jan 1 2000, In : Cellular and molecular neurobiology. 20, 6, p. 665-681 17 p.

Research output: Contribution to journalArticle

18 Scopus citations

Role of IL-5 in innate and adaptive immunity to larval Strongyloides stercoralis in mice

Herbert, D. R., Lee, J. J., Lee, N. A., Nolan, T. J., Schad, G. A. & Abraham, D., Oct 15 2000, In : Journal of Immunology. 165, 8, p. 4544-4551 8 p.

Research output: Contribution to journalArticle

Open Access
94 Scopus citations

Role of MUC1 in intestinal mucin accumulation in the CF mouse

Gendler, S. J., Hinojosa-Kurtzberg, M., Axelsson, K. A., Thomsson, K. A. & Hansson, G. C., Dec 1 2000, In : Pediatric pulmonology. 30, SUPPL. 20, 1 p.

Research output: Contribution to journalArticle

Selection and characterization of MUC1-specific CD8+ T cells from MUC1 transgenic mice immunized with dendritic-carcinoma fusion cells

Gong, J., Apostolopoulos, V., Chen, D., Chen, H., Koido, S., Gendler, S. J., Mckenzie, I. F. & Kufe, D., Dec 12 2000, In : Immunology. 101, 3, p. 316-324 9 p.

Research output: Contribution to journalArticle

49 Scopus citations

Striated muscle-specific β(1D)-integrin and FAK are involved in cardiac myocyte hypertrophic response pathway

Pham, C. G., Harpf, A. E., Keller, R. S., Vu, H. T., Shai, S. Y., Loftus, J. C. & Ross, R. S., Jan 1 2000, In : American Journal of Physiology - Heart and Circulatory Physiology. 279, 6 48-6, p. H2916-H2926

Research output: Contribution to journalArticle

104 Scopus citations

T cell suppression as a mechanism for tolerance to MUC1 antigen in MUC1 transgenic mice

Chen, D., Koido, S., Li, Y., Gendler, S. & Gong, J., May 31 2000, In : Breast Cancer Research and Treatment. 60, 2, p. 107-115 9 p.

Research output: Contribution to journalArticle

23 Scopus citations

The non-hydrolytic pathway of cystic fibrosis transmembrane conductance regulator ion channel gating

Aleksandrov, A. A., Chang, X. B., Aleksandrov, L. & Riordan, J. R., Jan 1 2000, In : Journal of Physiology. 528, 2, p. 259-265 7 p.

Research output: Contribution to journalArticle

61 Scopus citations
1999

A mutation in the α subunit of the platelet integrin α(IIb)β3 identifies a novel region important for ligand binding

Tozer, E. C., Baker, E. K., Ginsberg, M. H. & Loftus, J. C., Feb 1 1999, In : Blood. 93, 3, p. 918-924 7 p.

Research output: Contribution to journalArticle

30 Scopus citations

Anti-CD86 (B7.2) Treatment abolishes allergic airway hyperresponsiveness in mice

Haczku, A., Takeda, K., Redai, I., Hamelmann, E., Cieslewicz, G., Joetham, A., Loader, J., Lee, J. J., Irvin, C. & Gelfand, E. W., Jan 1 1999, In : American journal of respiratory and critical care medicine. 159, 5 I, p. 1638-1643 6 p.

Research output: Contribution to journalArticle

94 Scopus citations

Assembly and glycosylation of gel forming mucins: Implications for cystic fibrosis

Hansson, G. C., Axelsson, M. A. B., Asker, N., Johansson, M. E. V., Steel, D. M., Thomsson, K. A., Lindgren, K. A. S., Axelsson, K. A., Hinojosa-Kutzberg, M., Gendler, S. J., Nilsson, T. & Karlsson, N. G., Sep 1 1999, In : Pediatric pulmonology. 28, SUPPL. 19, p. 142-143 2 p.

Research output: Contribution to journalArticle

Bacterial conjunctivitis in Muc1 null mice

Kardon, R., Price, R. E., Julian, J. A., Lagow, E., Tseng, S. C. G., Gendler, S. J. & Carson, D. D., Jun 9 1999, In : Investigative Ophthalmology and Visual Science. 40, 7, p. 1328-1335 8 p.

Research output: Contribution to journalArticle

68 Scopus citations

Calogero-Moser models. II: Symmetries and foldings

Bordner, A. J., Sasaki, R. & Takasaki, K., Mar 1999, In : Progress of Theoretical Physics. 101, 3, p. 487-518 32 p.

Research output: Contribution to journalArticle

Open Access
33 Scopus citations

Calogero-Moser models. III: Elliptic potentials and twisting

Bordner, A. J. & Sasaki, R., Apr 1999, In : Progress of Theoretical Physics. 101, 4, p. 799-829 31 p.

Research output: Contribution to journalArticle

Open Access
30 Scopus citations

Chemoprevention of intestinal adenomas in the Apc(Min) mouse by piroxicam: Kinetics, strain effects and resistance to chemosuppression

Ritland, S. R. & Gendler, S. J., Jan 23 1999, In : Carcinogenesis. 20, 1, p. 51-58 8 p.

Research output: Contribution to journalArticle

92 Scopus citations

Differential discrimination of G-protein coupling of serotonin(1A) receptors from bovine hippocampus by an agonist and an antagonist

Harikumar, K. G. & Chattopadhyay, A., Sep 3 1999, In : FEBS Letters. 457, 3, p. 389-392 4 p.

Research output: Contribution to journalArticle

43 Scopus citations

Evaluation of 5-aminosalicylic acid (5-ASA) for cancer chemoprevention: Lack of efficacy against nascent adenomatous polyps in the Apc(Min) mouse

Ritland, S. R., Leighton, J. A., Hirsch, R. E., Morrow, J. D., Weaver, A. L. & Gendler, S. J., Apr 1 1999, In : Clinical Cancer Research. 5, 4, p. 855-863 9 p.

Research output: Contribution to journalArticle

39 Scopus citations

Fundamental signals that regulate eosinophil homing to the gastrointestinal tract

Mishra, A., Hogan, S. P., Lee, J. J., Foster, P. S. & Rothenberg, M. E., Jun 1999, In : Journal of Clinical Investigation. 103, 12, p. 1719-1727 9 p.

Research output: Contribution to journalArticle

Open Access
287 Scopus citations

Generalised Calogero-Moser models and universal Lax pair operators

Bordner, A. J., Corrigan, E. & Sasaki, R., Sep 1999, In : Progress of Theoretical Physics. 102, 3, p. 499-529 31 p.

Research output: Contribution to journalArticle

Open Access
56 Scopus citations

Influence of phosphorylation by protein kinase A on CFTR at the cell surface and endoplasmic reticulum

Seibert, F. S., Chang, X. B., Aleksandrov, A. A., Clarke, D. M., Hanrahan, J. W. & Riordan, J. R., Dec 6 1999, In : Biochimica et Biophysica Acta - Biomembranes. 1461, 2, p. 275-283 9 p.

Research output: Contribution to journalReview article

60 Scopus citations

Passively transferred anti-MUC1 antibodies cause neither autoimmune disorders nor immunity against transplanted tumors in MUC1 transgenic mice

Tempero, R. M., Rowse, G. J., Gendler, S. J. & Hollingsworth, M. A., Feb 4 1999, In : International Journal of Cancer. 80, 4, p. 595-599 5 p.

Research output: Contribution to journalArticle

19 Scopus citations

Removal of multiple arginine-framed trafficking signals overcomes misprocessing of ΔF508 CFTR present in most patients with cystic fibrosis

Chang, X. B., Cui, L., Hou, Y. X., Jensen, T. J., Aleksandrov, A. A., Mengos, A. & Riordan, J. R., Jul 1999, In : Molecular Cell. 4, 1, p. 137-142 6 p.

Research output: Contribution to journalArticle

112 Scopus citations

Soluble P-selectin glycoprotein ligand 1 inhibits ocular inflammation in a murine model of allergy

Strauss, E. C., Larson, K. A., Brenneise, I., Foster, C. S., Larsen, G. R., Lee, N. A. & Lee, J. J., Jun 9 1999, In : Investigative Ophthalmology and Visual Science. 40, 7, p. 1336-1342 7 p.

Research output: Contribution to journalArticle

26 Scopus citations

The macroimportance of the pulmonary immune microenvironment

Lee, N. A. & Lee, J. J., 1999, In : American journal of respiratory cell and molecular biology. 21, 3, p. 298-302 5 p.

Research output: Contribution to journalReview article

5 Scopus citations
1998

Abnormal heart rate regulation in GIRK4 knockout mice

Wickman, K., Nemec, J., Gendler, S. J. & Clapham, D. E., Jan 1998, In : Neuron. 20, 1, p. 103-114 12 p.

Research output: Contribution to journalArticle

297 Scopus citations

A microsatellite within the MUC1 locus at 1q21 is altered in the neoplastic cells of breast cancer patients

Waltz, M. R., Pandelidis, S. M., Pratt, W., Barnes, D., Swallow, D. M., Gendler, S. J. & Cohen, E. P., Jan 1 1998, In : Cancer Genetics and Cytogenetics. 100, 1, p. 63-67 5 p.

Research output: Contribution to journalArticle

10 Scopus citations

Calogero-moser models. I - A new formulation

Bordner, A. J., Corrigan, E. & Sasaki, R., Dec 1998, In : Progress of Theoretical Physics. 100, 6, p. 1107-1129 23 p.

Research output: Contribution to journalArticle

Open Access
60 Scopus citations

CD4+ lymphocytes provide MUC1-specific tumor immunity in vivo that is undetectable in vitro and is absent in MUC1 transgenic mice

Tempero, R. M., VanLith, M. L., Morikane, K., Rowse, G. J., Gendler, S. J. & Hollingsworth, M. A., Nov 15 1998, In : Journal of Immunology. 161, 10, p. 5500-5506 7 p.

Research output: Contribution to journalArticle

57 Scopus citations

Commuting charges of the quantum Korteweg-De Vries and Boussinesq theories from the reduction of W and W1+∞ algebras

Bordner, A. J., Mar 7 1998, In : Modern Physics Letters A. 13, 7, p. 541-552 12 p.

Research output: Contribution to journalArticle

Cystic fibrosis mice lacking Muc1 have reduced amounts of intestinal mucus

Parmley, R. R. & Gendler, S. J., Nov 15 1998, In : Journal of Clinical Investigation. 102, 10, p. 1798-1806 9 p.

Research output: Contribution to journalArticle

Open Access
64 Scopus citations

Dibasic protein kinase A sites regulate bursting rate and nucleotide sensitivity of the cystic fibrosis transmembrane conductance regulator chloride channel

Mathews, C. J., Tabcharani, J. A., Chang, X. B., Jensen, T. J., Riordan, J. R. & Hanrahan, J. W., Apr 15 1998, In : Journal of Physiology. 508, 2, p. 365-377 13 p.

Research output: Contribution to journalArticle

57 Scopus citations