Biochemistry and Molecular Biology

Research Output

1975

Some hematologic and blood chemistry values in two herds of American bison in Kansas.

Marler, R. J., Jan 1975, In : Journal of wildlife diseases. 11, 1, p. 97-100 4 p.

Research output: Contribution to journalArticle

Open Access
13 Scopus citations
1976

Encephalitis in a confined coyote.

Marler, R. J., Kruckenberg, S. M., Cook, J. E. & O'Keefe, C. M., Nov 1 1976, In : Journal of the American Veterinary Medical Association. 169, 9, p. 964-965 2 p.

Research output: Contribution to journalArticle

1 Scopus citations

Tyzzer's disease in two coyotes.

Marler, R. J. & Cook, J. E., Nov 1 1976, In : Journal of the American Veterinary Medical Association. 169, 9, p. 940-941 2 p.

Research output: Contribution to journalArticle

11 Scopus citations
1977

Atresia ani and rectovaginal fistula in Buffalo

Marler, R. J., Baker, W., Leipold, H. W., Cook, J. E. & Kruckenberg, S. M., Dec 1 1977, In : Journal of the American Veterinary Medical Association. 171, 9, p. 988-989 2 p.

Research output: Contribution to journalArticle

Intrahepatic Bile Duct Carcinoma with Metastasis to Bone in a Dog

Marler, R. J., Cook, J. E., Samuelson, M. L. & Kennedy, G. A., Sep 1977, In : Veterinary Pathology. 14, 5, p. 516-518 3 p.

Research output: Contribution to journalArticle

3 Scopus citations
1978

Extensive pulmonary arterial thrombosis without subsequent infarction.

Marler, R. J., Kennedy, G. A., Cook, J. E. & Willard, M., Feb 1 1978, In : Veterinary medicine, small animal clinician : VM, SAC. 73, 2, p. 145-147 3 p.

Research output: Contribution to journalArticle

1979

Experimentally induced leptospirosis in coyotes (Canis latrans).

Marler, R. J., Cook, J. E. & Kerr, A. I., Aug 1 1979, In : American Journal of Veterinary Research. 40, 8, p. 1115-1119 5 p.

Research output: Contribution to journalArticle

2 Scopus citations

Rabies in a horse.

Marler, R. J., Howard, D. R., Morris, P. G. & Johnson, J. L., Aug 1 1979, In : Journal of the American Veterinary Medical Association. 175, 3, p. 293-294 2 p.

Research output: Contribution to journalArticle

4 Scopus citations

Serologic survey for leptospirosis in coyotes in northcentral Kansas

Marler, R. J., Cook, J. E., Kerr, A. I. & Kruckenberg, S. M., Dec 1 1979, In : Journal of the American Veterinary Medical Association. 175, 9, p. 906-908 3 p.

Research output: Contribution to journalArticle

3 Scopus citations
1980

Incidence of a split α2-glycoprotein band in the electrophoretic pattern for serum of adenocarcinoma patients

Dermer, G. B., Silverman, L. M., Gendler, S. J. & Tokes, Z. A., Jan 1 1980, In : Clinical chemistry. 26, 3, p. 392-395 4 p.

Research output: Contribution to journalArticle

2 Scopus citations
1981

The synthesis of a proteinase inhibitor, alpha-1-antichymotrypsin, by human breast epithelial cells

Tokes, Z. A., Gendler, S. J. & Dermer, G. B., Dec 1 1981, In : Journal of Supramolecular and Cellular Biochemistry. 17, 1, p. 69-77 9 p.

Research output: Contribution to journalArticle

20 Scopus citations
1982

Synthesis of α1-Antichymotrypsin and α1-Acid Glycoprotein by Human Breast Epithelial Cells

Gendler, S. J., Dermer, G. B., Silverman, L. M. & Tökés, Z. A., Nov 1 1982, In : Cancer research. 42, 11, p. 4567-4573 7 p.

Research output: Contribution to journalArticle

46 Scopus citations
1983

Defective production of interleukin 1 and interleukin 2 in patients with systemic lupus erythematosus (SLE)

Linker-Israeli, M., Bakke, A. C., Kitridou, R. C., Gendler, S., Gillis, S. & Horwitz, D. A., Aug 4 1983, In : Journal of Immunology. 130, 6, p. 2651-2655 5 p.

Research output: Contribution to journalArticle

343 Scopus citations

Use of colloidal gold to examine fibrinogen binding to human platelets

Loftus, J. C. & Albrecht, R. M., Dec 1 1983, In : Scanning Electron Microscopy. 1983, 4, p. 1995-1999 5 p.

Research output: Contribution to journalArticle

11 Scopus citations
1984

Active proteinase inhibitors associated with human breast epithelial cells

Gendler, S. J. & TőKés, Z. A., 1984, In : Journal of cellular biochemistry. 26, 3, p. 157-167 11 p.

Research output: Contribution to journalArticle

8 Scopus citations

Platelet activation and cytoskeletal reorganization: high voltage electron microscopic examination of intact and triton-extracted whole mounts

Loftus, J. C., Choate, J. & Albrecht, R. M., 1984, In : Journal of Cell Biology. 98, 6, p. 2019-2025 7 p.

Research output: Contribution to journalArticle

Open Access
58 Scopus citations

Redistribution of the fibrinogen receptor of human platelets after surface activation

Loftus, J. C. & Albrecht, R. M., 1984, In : Journal of Cell Biology. 99, 3, p. 822-829 8 p.

Research output: Contribution to journalArticle

Open Access
88 Scopus citations

Toxic reactions evoked by glutaraldehyde‐fixed pericardium and cardiac valve tissue bioprosthesis

Gendler, E., Gendler, S. & Nimni, M. E., Sep 1984, In : Journal of Biomedical Materials Research. 18, 7, p. 727-736 10 p.

Research output: Contribution to journalArticle

145 Scopus citations
1985

Active proteinase inhibitors associated with human breast cancer cells

Gendler, S. J. & Tokes, Z. A., Jan 1 1985, In : Proceedings of the American Association for Cancer Research. VOL. 26, p. No. 216

Research output: Contribution to journalArticle

1986

Expression of an active proteinase inhibitor, α1-antichymotrypsin, by human breast epithelial cells

Gendler, S. J. & Tökés, Z. A., Jun 19 1986, In : BBA - General Subjects. 882, 2, p. 242-253 12 p.

Research output: Contribution to journalArticle

4 Scopus citations

Formation of deletions after initiation of simian virus 40 replication: Influence of packaging limit of the capsid

Chang, X. B. & Wilson, J. H., 1986, In : Journal of virology. 58, 2, p. 393-401 9 p.

Research output: Contribution to journalArticle

Open Access
20 Scopus citations

Immunologic relationship between platelet membrane glycoprotein GPIIb/IIIa and cell surface molecules expressed by a variety of cells

Plow, E. F., Loftus, J. C., Levin, E. G., Fair, D. S., Dixon, D., Forsyth, J. & Ginsberg, M. H., 1986, In : Proceedings of the National Academy of Sciences of the United States of America. 83, 16, p. 6002-6006 5 p.

Research output: Contribution to journalArticle

77 Scopus citations
1987

Cloning of partial cDNA encoding differentiation and tumor-associated mucin glycoproteins expressed by human mammary epithelium

Gendler, S. J., Burchell, J. M., Duhig, T., Lamport, D., White, R., Parker, M. & Taylor-Papadimitriou, J., 1987, In : Proceedings of the National Academy of Sciences of the United States of America. 84, 17, p. 6060-6064 5 p.

Research output: Contribution to journalArticle

Open Access
245 Scopus citations

Immunochemical and amino-terminal sequence comparison of two cytoadhesins indicates they contain similar or identical β subunits and distinct α subunits

Ginsberg, M. H., Loftus, J., Ryckwaert, J. J., Pierschbacher, M., Pytela, R., Ruoslahti, E. & Plow, E. F., Sep 15 1987, In : Journal of Biological Chemistry. 262, 12, p. 5437-5440 4 p.

Research output: Contribution to journalArticle

56 Scopus citations

Immunological analysis of mucin molecules expressed by normal and malignant mammary epithelial cells

Griffiths, A. B., Burchell, J., Gendler, S., Lewis, A., Blight, K., Tilly, R. & Taylor‐Papadimitriou, J., Sep 15 1987, In : International Journal of Cancer. 40, 3, p. 319-327 9 p.

Research output: Contribution to journalArticle

43 Scopus citations
Open Access
29 Scopus citations

Molecular cloning and chemical synthesis of a region of platelet glycoprotein IIb involved in adhesive function

Loftus, J. C., Plow, E. F., Frelinger, A. L., D'Souza, S. E., Dixon, D., Lacy, J., Sorge, J. & Ginsberg, M. H., 1987, In : Proceedings of the National Academy of Sciences of the United States of America. 84, 20, p. 7114-7118 5 p.

Research output: Contribution to journalArticle

Open Access
61 Scopus citations
1988

A highly immunogenic region of a human polymorphic epithelial mucin expressed by carcinomas is made up of tandem repeats

Gendler, S., Taylor-Papadimitriou, J., Duhig, T., Rothbard, J. & Burchel, J., Jan 1 1988, In : Journal of Biological Chemistry. 263, 26, p. 12820-12823 4 p.

Research output: Contribution to journalArticle

475 Scopus citations

Alternative proteolytic processing of platelet membrane glycoprotein IIb

Loftus, J. C., Plow, E. F., Jennings, L. K. & Ginsberg, M. H., Jan 1 1988, In : Journal of Biological Chemistry. 263, 23, p. 11025-11028 4 p.

Research output: Contribution to journalArticle

33 Scopus citations

cDNA clones for human platelet GPIIb corresponding to mRNA from megakaryocytes and HEL cells: Evidence for an extensive homology to other Arg‐Gly‐Asp adhesion receptors

UZAN, G., FRACHET, P., LAJMANOVICH, A., PRANDINI, MH. H., DENARIER, E., DUPERRAY, A., LOFTUS, J., GINSBERG, M., PLOW, E. & MARGUERIE, G., Jan 1988, In : European Journal of Biochemistry. 171, 1-2, p. 87-93 7 p.

Research output: Contribution to journalArticle

18 Scopus citations

Close linkage of PUM and SPTA within chromosome band 1q21

MIDDLETON‐PRICE, H., GENDLER, S. & MALCOLM, S., Jul 1988, In : Annals of Human Genetics. 52, 4, p. 273-278 6 p.

Research output: Contribution to journalArticle

20 Scopus citations

Cytoadhesins, integrins, and platelets

Ginsberg, M. H., Loftus, J. C. & Plow, E. F., 1988, In : Thrombosis and Haemostasis. 59, 1, p. 1-6 6 p.

Research output: Contribution to journalReview article

217 Scopus citations

Molecular aspects of mucins

Taylor-Papadimitriou, J. & Gendler, S. J., Jan 1 1988, In : Cancer Reviews. 11-12, p. 11-24 14 p.

Research output: Contribution to journalArticle

40 Scopus citations

Occupancy of an adhesive glycoprotein receptor modulates expression of an antigenic site involved in cell adhesion

Frelinger, A. L., Lam, S. C. T., Plow, E. F., Smith, M. A., Loftus, J. C. & Ginsberg, M. H., Dec 1 1988, In : Journal of Biological Chemistry. 263, 25, p. 12397-12402 6 p.

Research output: Contribution to journalArticle

204 Scopus citations

Platelets and the adhesion receptor superfamily.

Ginsberg, M. H., Loftus, J. & Plow, E. F., Dec 1 1988, In : Progress in clinical and biological research. 283, p. 171-195 25 p.

Research output: Contribution to journalReview article

10 Scopus citations

The human tumour-associated epithelial mucins are coded by an expressed hypervariable gene locus PUM

Swallow, D. M., Gendler, S., Griffiths, B., Corney, G., Taylor-Papadimitriou, J. & Bramwell, M. E., 1988, In : Nature. 328, 6125, p. 82-84 3 p.

Research output: Contribution to journalArticle

207 Scopus citations
1989

A core protein epitope of the polymorphic epithelial mucin detected by the monoclonal antibody SM‐3 is selectively exposed in a range of primary carcinomas

Girling, A., Bartkova, J., Burchell, J., Gendler, S., Gillett, C. & Taylor‐Papadimitriou, J., Jun 15 1989, In : International Journal of Cancer. 43, 6, p. 1072-1076 5 p.

Research output: Contribution to journalArticle

295 Scopus citations

A short sequence, within the amino acid tandem repeat of a cancer‐associated mucin, contains immunodominant epitopes

Burchell, J., Taylor‐Papadimitriou, J., Boshell, M., Gendler, S. & Duhig, T., Oct 15 1989, In : International Journal of Cancer. 44, 4, p. 691-696 6 p.

Research output: Contribution to journalArticle

211 Scopus citations

Clonal allele loss in gastrointestinal cancers

Fey, M. F., Hesketh, C., Wainscoat, J. S., Gendler, S. & Thein, S. L., May 1989, In : British journal of cancer. 59, 5, p. 750-754 5 p.

Research output: Contribution to journalArticle

56 Scopus citations

Comparison of Filler DNA at immune, nonimmune, and oncogenic rearrangements suggests multiple mechanisms of formation

Roth, D. B., Chang, X. B. & Wilson, J. H., 1989, In : Molecular and cellular biology. 9, 7, p. 3049-3057 9 p.

Research output: Contribution to journalArticle

106 Scopus citations

Efficient surface expression of platelet GPIIb-IIIa requires both subunits

O'Toole, T. E., Loftus, J. C., Plow, E. F., Glass, A. A., Harper, J. R. & Ginsberg, M. H., 1989, In : Blood. 74, 1, p. 14-18 5 p.

Research output: Contribution to journalArticle

Open Access
120 Scopus citations

Insertional Mutations in Transgenic Mice

Costantini, F., Radice, G., Lee, J. J., Perry, W. & Son, H. J., Jan 1 1989, In : Progress in Nucleic Acid Research and Molecular Biology. 36, C, p. 159-169 11 p.

Research output: Contribution to journalArticle

37 Scopus citations

Primary cells and established cell lines join DNA ends with the same efficiency relative to homologous recombination

Zheng, H., Chang, X. B. & Wilson, J. H., Sep 1989, In : Plasmid. 22, 2, p. 99-105 7 p.

Research output: Contribution to journalArticle

2 Scopus citations
1990

Affinity modulation of the αIIbβ3 integrin (platelet GPIIb-IIIa) is an intrinsic property of the receptor

O'Toole, T. E., Loftus, J. C., Du, X., Glass, A. A., Ruggeri, Z. M., Shattil, S. J., Plow, E. F. & Ginsberg, M. H., Nov 1990, In : Molecular biology of the cell. 1, 12, p. 883-893 11 p.

Research output: Contribution to journalArticle

219 Scopus citations

A β3 integrin mutation abolishes ligand binding and alters divalent cation-dependent conformation

Loftus, J. C., O'Toole, T. E., Plow, E. F., Glass, A., Frelinger, A. L. & Ginsberg, M. H., Jan 1 1990, In : Science. 249, 4971, p. 915-918 4 p.

Research output: Contribution to journalArticle

314 Scopus citations

Cytogenetic methods for the mouse: Preparation of chromosomes, karyotyping, and in situ hybridization

Lee, J. J., Warburton, D. & Robertson, E. J., Aug 15 1990, In : Analytical Biochemistry. 189, 1, p. 1-17 17 p.

Research output: Contribution to journalReview article

31 Scopus citations

Ligand binding to integrins: Common and ligand specific recognition mechanisms

Ginsberg, M. H., Loftus, J. C., D'Souza, S. & Plow, E. F., Dec 11 1990, In : Cell Differentiation and Development. 32, 3, p. 203-213 11 p.

Research output: Contribution to journalArticle

17 Scopus citations

Molecular cloning and expression of human tumor-associated polymorphic epithelial mucin

Gendler, S. J., Lancaster, C. A., Taylor-Papadimitriou, J., Duhig, T., Peat, N., Burchell, J., Pemberton, L., Lalani, E. N. & Wilson, D., Sep 28 1990, In : Journal of Biological Chemistry. 265, 25, p. 15286-15293 8 p.

Research output: Contribution to journalArticle

814 Scopus citations

Mucin antigens: Molecular structure and potential use in immunotherapy

Taylor-Papadimitriou, J., Lalani, E. N., Burchell, J. & Gendler, S. J., Jan 1 1990, In : Journal of Nuclear Medicine and Allied Sciences. 34, 3 SUPPL., p. 144-150 7 p.

Research output: Contribution to journalArticle

3 Scopus citations

Structure and expression of the human polymorphic epithelial mucin gene: an expressed VNTR unit

Lancaster, C. A., Peat, N., Duhig, T., Wilson, D., Taylor-Papadimitriou, J. & Gendler, S. J., Dec 31 1990, In : Biochemical and Biophysical Research Communications. 173, 3, p. 1019-1029 11 p.

Research output: Contribution to journalArticle

120 Scopus citations