Biochemistry and Molecular Biology

Research Output 1993 2018

2006
40 Citations (Scopus)

Increased levels of mucins in the cystic fibrosis mouse small intestine, and modulator effects of the Muc1 mucin expression

Malmberg, E. K., Noaksson, K. A., Phillipson, M., Johansson, M. E. V., Hinojosa-Kurtzberg, M., Holm, L., Gendler, S. J. & Hansson, G. C., 2006, In : American Journal of Physiology - Gastrointestinal and Liver Physiology. 291, 2

Research output: Contribution to journalArticle

Mucin-1
Mucins
Cystic Fibrosis
Small Intestine
Mucus
59 Citations (Scopus)

Lack of eosinophil peroxidase or major basic protein impairs defense against murine filarial infection

Specht, S., Saeftel, M., Arndt, M., Endl, E., Dubben, B., Lee, N. A., Lee, J. J. & Hoerauf, A., Sep 2006, In : Infection and Immunity. 74, 9, p. 5236-5243 8 p.

Research output: Contribution to journalArticle

Eosinophil Peroxidase
Eosinophil Granule Proteins
Infection
Proteins
Helminths
62 Citations (Scopus)

MUC1 alters oncogenic events and transcription in human breast cancer cells

Hattrup, C. L. & Gendler, S. J., Jul 17 2006, In : Breast Cancer Research. 8, 4, R37.

Research output: Contribution to journalArticle

Small Interfering RNA
Breast Neoplasms
Apoptosis
Cell Line
Neoplasms
20 Citations (Scopus)

MUC1 cytoplasmic tail detection using CT33 polyclonal and CT2 monoclonal antibodies in breast and colorectal tissue

Croce, M. V., Isla-Larrain, M., Remes-Lenicov, F., Colussi, A. G., Lacunza, E., Kim, K. C., Gendler, S. J. & Segal-Eiras, A., Jul 2006, In : Histology and Histopathology. 21, 7-9, p. 849-855 7 p.

Research output: Contribution to journalArticle

Breast
Monoclonal Antibodies
Colorectal Neoplasms
Antibodies
Western Blotting
93 Citations (Scopus)

Novel approach to inhibit asthma-mediated lung inflammation using Anti-CD147 intervention

Gwinn, W. M., Damsker, J. M., Falahati, R., Okwumabua, I., Kelly-Welch, A., Keegan, A. D., Vanpouille, C., Lee, J. J., Dent, L. A., Leitenberg, D., Bukrinsky, M. I. & Constant, S. L., Oct 1 2006, In : Journal of Immunology. 177, 7, p. 4870-4879 10 p.

Research output: Contribution to journalArticle

Cyclophilins
Pneumonia
Asthma
T-Lymphocytes
Leukocytes
119 Citations (Scopus)

Pivotal Advance: Eosinophil infiltration of solid tumors is an early and persistent inflammatory host response

Cormier, S. A., Taranova, A. G., Bedient, C., Nguyen, T., Protheroe, C., Pero, R., Dimina, D., Ochkur, S. I., O'Neill, K., Colbert, D., Lombari, T. R., Constant, S., McGarry, M. P., Lee, J. J. & Lee, N. A., Jun 2006, In : Journal of Leukocyte Biology. 79, 6, p. 1131-1139 9 p.

Research output: Contribution to journalArticle

Eosinophils
Neoplasms
Eosinophilia
Eosinophil Major Basic Protein
Th2 Cells
86 Citations (Scopus)

Pro-oxidative diesel exhaust particle chemicals inhibit LPS-induced dendritic cell responses involved in T-helper differentiation

Chan, R. C. F., Wang, M., Li, N., Yanagawa, Y., Onoé, K., Lee, J. J. & Nel, A. E., Aug 2006, In : Journal of Allergy and Clinical Immunology. 118, 2, p. 455-465 11 p.

Research output: Contribution to journalArticle

Vehicle Emissions
Dendritic Cells
Particulate Matter
Interleukin-12
Oxidative Stress
9 Citations (Scopus)

Regulatory role of CD8+ T lymphocytes in bone marrow eosinophilopoiesis

Rådinger, M., Sergejeva, S., Johansson, A. K., Malmhäll, C., Bossios, A., Sjöstrand, M., Lee, J. J. & Lötvall, J., Jan 6 2006, In : Respiratory Research. 7, 83.

Research output: Contribution to journalArticle

Bone Marrow
T-Lymphocytes
Allergens
Interleukin-5
Eosinophilia
7 Citations (Scopus)

Replacement of the positively charged Walker A lysine residue with a hydrophobic leucine residue and conformational alterations caused by this mutation in MRP1 impair ATP binding and hydrolysis

Buyse, F., Hou, Y. X., Vigano, C., Zhao, Q., Ruysschaert, J. M. & Chang, X-B. D., Jul 1 2006, In : Biochemical Journal. 397, 1, p. 121-130 10 p.

Research output: Contribution to journalArticle

P-Glycoprotein
Leucine
Lysine
Hydrolysis
Solute transport
87 Citations (Scopus)

Role of eosinophils and neutrophils in innate and adaptive protective immunity to larval Strongyloides stercoralis in mice

Galioto, A. M., Hess, J. A., Nolan, T. J., Schad, G. A., Lee, J. J. & Abraham, D., Oct 2006, In : Infection and Immunity. 74, 10, p. 5730-5738 9 p.

Research output: Contribution to journalArticle

Strongyloides stercoralis
Adaptive Immunity
Eosinophils
Neutrophils
Larva
61 Citations (Scopus)

Sodium iodide symporter-mediated radioiodide imaging and therapy of ovarian tumor xenografts in mice

Dwyer, R. M., Bergert, E. R., O'Connor, M. K., Gendler, S. J. & Morris, J. C., Jan 2006, In : Gene Therapy. 13, 1, p. 60-66 7 p.

Research output: Contribution to journalArticle

Heterografts
Ovarian Neoplasms
Neoplasms
Iodides
Tumor Burden
631 Citations (Scopus)

Structural Basis for the Methylation State-Specific Recognition of Histone H4-K20 by 53BP1 and Crb2 in DNA Repair

Botuyan, M. V., Lee, J., Ward, I. M., Kim, J. E., Thompson, J. R., Chen, J. & Mer, G., Dec 29 2006, In : Cell. 127, 7, p. 1361-1373 13 p.

Research output: Contribution to journalArticle

Methylation
DNA Repair
Histones
Repair
DNA
28 Citations (Scopus)

Transmembrane segment peptides can disrupt cholecystokinin receptor oligomerization without affecting receptor function

Harikumar, K. G., Dong, M., Cheng, Z., Pinon, D. I., Lybrand, T. P. & Miller, L. J., Dec 12 2006, In : Biochemistry. 45, 49, p. 14706-14716 11 p.

Research output: Contribution to journalArticle

Cholecystokinin Receptors
Oligomerization
Bioluminescence
Energy Transfer
Peptides
33 Citations (Scopus)

Tyrosines in the MUC1 cytoplasmic tail modulate transcription via the extracellular signal-regulated kinase 1/2 and nuclear factor-κB pathways

Thompson, E. J., Shanmugam, K., Hattrup, C. L., Kotlarczyk, K. L., Gutierrez, A., Bradley, J. M., Mukherjee, P. & Gendler, S. J., Jul 2006, In : Molecular Cancer Research. 4, 7, p. 489-497 9 p.

Research output: Contribution to journalArticle

Mitogen-Activated Protein Kinase 3
Mitogen-Activated Protein Kinase 1
Tyrosine
Phosphorylation
Cell Line
19 Citations (Scopus)
G-Protein-Coupled Receptors
GTP-Binding Proteins
Secretin
Fluorescence
Peptides
2005

A downer Nubian goat with coughing

Gades, N. M., Okerman, R., Twernbold, D., Thompson, K., Bjertness, L. & Marler, R. J., Sep 2005, In : Lab Animal. 34, 8, p. 24-25 2 p.

Research output: Contribution to journalArticle

Strongylida Infections
Parasitic Lung Diseases
Metastrongyloidea
Goat Diseases
Lentivirus Infections
12 Citations (Scopus)

Analysis of the cellular and molecular mechanisms of trophic action of a misspliced form of the type B cholecystokinin receptor present in colon and pancreatic cancer

Cheng, Z. J., Harikumar, K. G., Ding, W. Q., Holicky, E. L. & Miller, L. J., May 10 2005, In : Cancer Letters. 222, 1, p. 95-105 11 p.

Research output: Contribution to journalArticle

Cholecystokinin B Receptor
Pancreatic Neoplasms
Colonic Neoplasms
Cholecystokinin A Receptor
Calcium
49 Citations (Scopus)

A preclinical large animal model of adenovirus-mediated expression of the sodium-iodide symporter for radioiodide imaging and therapy of locally recurrent prostate cancer

Dwyer, R. M., Schatz, S. M., Bergert, E. R., Myers, R. M., Harvey, M. E., Classic, K. L., Blanco, M. C., Frisk, C. S., Marler, R. J., Davis, B. J., O'Connor, M. K., Russell, S. J. & Morris, J. C., Nov 2005, In : Molecular Therapy. 12, 5, p. 835-841 7 p.

Research output: Contribution to journalArticle

Adenoviridae
Prostatic Neoplasms
Animal Models
Prostate
Iodides
11 Citations (Scopus)

Decreased size and survival of weanling mice in litters of IL-5 -/- mice are a consequence of the IL-5 deficiency in nursing dams

Colbert, D. C., McGarry, M. P., O'Neill, K., Lee, N. A. & Lee, J. J., May 2005, In : Contemporary Topics in Laboratory Animal Science. 44, 3, p. 53-55 3 p.

Research output: Contribution to journalArticle

interleukin-5
Interleukin-5
breast feeding
weanlings
litters (young animals)
57 Citations (Scopus)

Differential effects of modification of membrane cholesterol and sphingolipids on the conformation, function, and trafficking of the G protein-coupled cholecystokinin receptor

Harikumar, K. G., Puri, V., Singh, R. D., Hanada, K., Pagano, R. E. & Miller, L. J., Jan 21 2005, In : Journal of Biological Chemistry. 280, 3, p. 2176-2185 10 p.

Research output: Contribution to journalArticle

Cholecystokinin Receptors
Sphingolipids
G-Protein-Coupled Receptors
GTP-Binding Proteins
Conformations
29 Citations (Scopus)

Distinct molecular mechanisms for agonist peptide binding to types A and B cholecystokinin receptors demonstrated using fluorescence spectroscopy

Harikumar, K. G., Clain, J., Pinon, D. I., Bong, M. & Miller, L. J., Jan 14 2005, In : Journal of Biological Chemistry. 280, 2, p. 1044-1050 7 p.

Research output: Contribution to journalArticle

Cholecystokinin A Receptor
Cholecystokinin B Receptor
Fluorescence Spectrometry
Fluorescence spectroscopy
Peptides
78 Citations (Scopus)

Eosinophil degranulation: An evolutionary vestige or a universally destructive effector function?

Lee, J. J. & Lee, N. A., Aug 2005, In : Clinical and Experimental Allergy. 35, 8, p. 986-994 9 p.

Research output: Contribution to journalArticle

Immunologic Cytotoxicity
Eosinophil Granule Proteins
Cytoplasmic Granules
Species Specificity
Cell Degranulation
20 Citations (Scopus)

Eosinophils, but not eosinophil peroxidase or major basic protein, are important for host protection in experimental Brugia pahangi infection

Ramalingam, T., Porte, P., Lee, J. & Rajan, T. V., Dec 2005, In : Infection and Immunity. 73, 12, p. 8442-8443 2 p.

Research output: Contribution to journalArticle

Brugia pahangi
Eosinophil Peroxidase
Eosinophils
Eosinophilia
Infection
98 Citations (Scopus)

Eosinophils alter colonic epithelial barrier function: Role for major basic protein

Furuta, G. T., Nieuwenhuis, E. E. S., Karhausen, J., Gleich, G., Blumberg, R. S., Lee, J. J. & Ackerman, S. J., Nov 2005, In : American Journal of Physiology - Gastrointestinal and Liver Physiology. 289, 5 52-5

Research output: Contribution to journalArticle

Eosinophils
Eosinophil-Derived Neurotoxin
Coculture Techniques
Gastrointestinal Diseases
Colitis
13 Citations (Scopus)

Fluorescence resonance energy transfer analysis of the antagonist- and partial agonist-occupied states of the cholecystokinin receptor

Harikumar, K. G. & Miller, L. J., May 13 2005, In : Journal of Biological Chemistry. 280, 19, p. 18631-18635 5 p.

Research output: Contribution to journalArticle

Cholecystokinin Receptors
Fluorescence Resonance Energy Transfer
Ligands
Conformations
Esters
74 Citations (Scopus)

In vivo radioiodide imaging and treatment of breast cancer xenografts after MUC1-driven expression of the sodium iodide symporter

Dwyer, R. M., Bergert, E. R., O'Connor, M. K., Gendler, S. J. & Morris, J. C., Feb 15 2005, In : Clinical Cancer Research. 11, 4, p. 1483-1489 7 p.

Research output: Contribution to journalArticle

Heterografts
Breast Neoplasms
Iodides
Neoplasms
Therapeutics
114 Citations (Scopus)

Mechanisms underlying the growth inhibitory effects of the cyclo-oxygenase-2 inhibitor celecoxib in human breast cancer cells.

Basu, G. D., Pathangey, L. B., Tinder, T. L., Gendler, S. J. & Mukherjee, P., 2005, In : Breast cancer research : BCR. 7, 4

Research output: Contribution to journalArticle

Celecoxib
Cyclooxygenase Inhibitors
Breast Neoplasms
Growth
Prostaglandin-Endoperoxide Synthases
46 Citations (Scopus)

MUC1 (CD227) interacts with lck tyrosine kinase in Jurkat lymphoma cells and normal T cells

Mukherjee, P., Tinder, T. L., Basu, G. D. & Gendler, S. J., Jan 2005, In : Journal of Leukocyte Biology. 77, 1, p. 90-99 10 p.

Research output: Contribution to journalArticle

Lymphocyte Specific Protein Tyrosine Kinase p56(lck)
Jurkat Cells
Protein-Tyrosine Kinases
Lymphoma
T-Cell Antigen Receptor
37 Citations (Scopus)

Muc1 affects c-Src signaling in PyV MT-induced mammary tumorigenesis

Al Masri, A. & Gendler, S. J., Sep 1 2005, In : Oncogene. 24, 38, p. 5799-5808 10 p.

Research output: Contribution to journalArticle

Carcinogenesis
Breast
Phosphatidylinositol 3-Kinase
Mouse mammary tumor virus
Catenins
17 Citations (Scopus)

Nucleotide dissociation from NBD1 promotes solute transport by MRP1

Yang, R., McBride, A., Hou, Y. X., Goldberg, A. & Chang, X-B. D., Mar 1 2005, In : Biochimica et Biophysica Acta - Biomembranes. 1668, 2, p. 248-261 14 p.

Research output: Contribution to journalArticle

Solute transport
Nucleotides
Adenosine Triphosphate
Leukotriene C4
Hydrolysis
71 Citations (Scopus)

Pancreatic cancer pain and its correlation with changes in tumor vasculature, macrophage infiltration, neuronal innervation, body weight and disease progression

Lindsay, T. H., Jonas, B. M., Sevcik, M. A., Kubota, K., Halvorson, K. G., Ghilardi, J. R., Kuskowski, M. A., Stelow, E. B., Mukherjee, P., Gendler, S. J., Wong, G. Y. & Mantyh, P. W., Dec 15 2005, In : Pain. 119, 1-3, p. 233-246 14 p.

Research output: Contribution to journalArticle

Pancreatic Neoplasms
Disease Progression
Macrophages
Body Weight
Pain
51 Citations (Scopus)

Targeted measles virus vector displaying echistatin infects endothelial cells via αvβ3 and leads to tumor regression

Hallak, L. K., Merchan, J. R., Storgard, C. M., Loftus, J. C. & Russell, S. J., Jun 15 2005, In : Cancer Research. 65, 12, p. 5292-5300 9 p.

Research output: Contribution to journalArticle

Endogenous Retroviruses
Measles virus
Endothelial Cells
Neoplasms
Integrins
98 Citations (Scopus)

The tyrosine kinase Pyk2 promotes migration and invasion of glioma cells

Lipinski, C. A., Tran, N., Menashi, E., Rohl, C., Kloss, J., Bay, R. C., Berens, M. E. & Loftus, J. C., May 2005, In : Neoplasia. 7, 5, p. 435-445 11 p.

Research output: Contribution to journalArticle

Focal Adhesion Kinase 2
Glioma
Protein-Tyrosine Kinases
Cell Movement
Glioblastoma
54 Citations (Scopus)

Tumor-associated carbohydrate antigens: A possible avenue for cancer prevention

Xu, Y., Sette, A., Sidney, J., Gendler, S. J. & Franco, A., Aug 2005, In : Immunology and Cell Biology. 83, 4, p. 440-448 9 p.

Research output: Contribution to journalArticle

Tumor-Associated Carbohydrate Antigens
Glycopeptides
T-cells
Vaccines
T-Lymphocytes
3 Citations (Scopus)

Validation of a mouse adhesion reduction model using Seprafilm®

Morse, A. N., Hammer, R. A., Cornella, J. L. & Loftus, J. C., Dec 2005, In : Journal of Gynecologic Surgery. 21, 4, p. 147-153 7 p.

Research output: Contribution to journalArticle

Carboxymethylcellulose Sodium
Hyaluronic Acid
Cecum
Membranes
Research Personnel
2004
111 Citations (Scopus)

A3 adenosine receptor signaling contributes to airway inflammation and mucus production in adenosine deaminase-deficient mice

Young, H. W. J., Molina, J. G., Dimina, D., Zhong, H., Jacobson, M., Chan, L. N. L., Chan, T. S., Lee, J. J. & Blackburn, M. R., Jul 15 2004, In : Journal of Immunology. 173, 2, p. 1380-1389 10 p.

Research output: Contribution to journalArticle

Adenosine A3 Receptors
Mucus
Eosinophils
Adenosine
Inflammation
19 Citations (Scopus)

Allergen-induced traffic of bone marrow eosinophils, neutrophils and lymphocytes to airways

Johansson, A. K., Sergejeva, S., Sjöstrand, M., Lee, J. J. & Lötvall, J., Nov 2004, In : European Journal of Immunology. 34, 11, p. 3135-3145 11 p.

Research output: Contribution to journalArticle

Eosinophils
Allergens
Neutrophils
Bone Marrow
Lymphocytes
128 Citations (Scopus)

Cyclooxygenase-2 inhibitor induces apoptosis in breast cancer cells in an in vivo model of spontaneous metastatic breast cancer

Basu, G. D., Pathangey, L. B., Tinder, T. L., LaGioia, M., Gendler, S. J. & Mukherjee, P., Nov 2004, In : Molecular Cancer Research. 2, 11, p. 632-642 11 p.

Research output: Contribution to journalArticle

Celecoxib
Cyclooxygenase 2 Inhibitors
Apoptosis
Breast Neoplasms
Therapeutics
540 Citations (Scopus)

Defining a link with asthma in mice congenitally deficient in eosinophils

Lee, J. J., Dimina, D., Macias, M. P., Ochkur, S. I., McGarry, M. P., O'Neill, K. R., Protheroe, C., Pero, R., Nguyen, T., Cormier, S. A., Lenkiewicz, E., Colbert, D., Rinaldi, L., Ackerman, S. J., Irvin, C. G. & Lee, N. A., Sep 17 2004, In : Science. 305, 5691, p. 1773-1776 4 p.

Research output: Contribution to journalArticle

Eosinophils
Asthma
Lung
Parasitic Diseases
Mucus
64 Citations (Scopus)

Designer Glycopeptides for Cytotoxic T Cell-based Elimination of Carcinomas

Xu, Y., Gendler, S. J. & Franco, A., Mar 1 2004, In : Journal of Experimental Medicine. 199, 5, p. 707-716 10 p.

Research output: Contribution to journalArticle

Glycopeptides
Tumor-Associated Carbohydrate Antigens
Carcinoma
T-Lymphocytes
Neoplasms
9 Citations (Scopus)

Downregulation of Muc1 in MMTV-c-Neu tumors

Adriance, M. C. & Gendler, S. J., Jan 22 2004, In : Oncogene. 23, 3, p. 697-705 9 p.

Research output: Contribution to journalArticle

Down-Regulation
Human Mammary Glands
Transfection
Neoplasms
Breast Neoplasms
13 Citations (Scopus)

Effects of raloxifene hydrochloride on endometrial cancer cells in vitro

Hibner, M., Magrina, J. F., Lefler, S. R., Cornella, J. L., Pizarro, A. R. & Loftus, J. C., Jun 2004, In : Gynecologic Oncology. 93, 3, p. 642-646 5 p.

Research output: Contribution to journalArticle

Endometrial Neoplasms
Estradiol
Growth
Confidence Intervals
In Vitro Techniques
165 Citations (Scopus)

Endocytic trafficking routes of wild type and ΔF508 cystic fibrosis transmembrane conductance regulator

Gentzsch, M., Chang, X-B. D., Cui, L., Wu, Y., Ozols, V. V., Choudhury, A., Pagano, R. E. & Riordan, J. R., Jun 2004, In : Molecular Biology of the Cell. 15, 6, p. 2684-2696 13 p.

Research output: Contribution to journalArticle

Cystic Fibrosis Transmembrane Conductance Regulator
Endosomes
rab GTP-Binding Proteins
trans-Golgi Network
Proteasome Inhibitors
43 Citations (Scopus)

Eosinophil degranulation in the allergic lung of mice primarily occurs in the airway lumen

Clark, K., Simson, L., Newcombe, N., Koskinen, A. M. L., Mattes, J., Lee, N. A., Lee, J. J., Dent, L. A., Matthaei, K. I. & Foster, P. S., Jun 2004, In : Journal of Leukocyte Biology. 75, 6, p. 1001-1009 9 p.

Research output: Contribution to journalArticle

Eosinophils
Lung
Bronchoalveolar Lavage Fluid
Eosinophil Granule Proteins
Eosinophil Peroxidase
18 Citations (Scopus)

Fluorescent modified phosphatidylcholine floppase activity of reconstituted multidrug resistance-associated protein MRP1

Huang, Z., Chang, X-B. D., Riordan, J. R. & Huang, Y., Jan 28 2004, In : Biochimica et Biophysica Acta - Biomembranes. 1660, 1, p. 155-163 9 p.

Research output: Contribution to journalArticle

Multidrug Resistance-Associated Proteins
Phosphatidylcholines
Adenosine Triphosphate
verlukast
Proteins
57 Citations (Scopus)

Glycocalyx restricts adenoviral vector access to apical receptors expressed on respiratory epithelium in vitro and in vivo: Role for tethered mucins as barriers to lumenal infection

Stonebraker, J. R., Wagner, D., Lefensty, R. W., Burns, K., Gendler, S. J., Bergelson, J. M., Boucher, R. C., O'Neal, W. K. & Pickles, R. J., Dec 2004, In : Journal of Virology. 78, 24, p. 13755-13768 14 p.

Research output: Contribution to journalArticle

respiratory mucosa
Glycocalyx
Respiratory Mucosa
mucins
Mucins
55 Citations (Scopus)

G-protein-dependent cell surface dynamics of the human serotonin 1A receptor tagged to yellow fluorescent protein

Pucadyil, T. J., Kalipatnapu, S., Harikumar, K. G., Rangaraj, N., Karnik, S. S. & Chattopadhyay, A., Dec 21 2004, In : Biochemistry. 43, 50, p. 15852-15862 11 p.

Research output: Contribution to journalArticle

Receptor, Serotonin, 5-HT1A
GTP-Binding Proteins
Signal transduction
Cells
Signal Transduction
58 Citations (Scopus)

Immunoglobulin E and Eosinophil-Dependent Protective Immunity to Larval Onchocerca volvulus in Mice Immunized with Irradiated Larvae

Abraham, D., Leon, O., Schnyder-Candrian, S., Wang, C. C., Galioto, A. M., Kerepesi, L. A., Lee, J. J. & Lustigman, S., Feb 2004, In : Infection and Immunity. 72, 2, p. 810-817 8 p.

Research output: Contribution to journalArticle

Onchocerca volvulus
Eosinophils
Immunoglobulin E
Larva
Immunity
122 Citations (Scopus)

Immunopathogenesis of Experimental Ulcerative Colitis is Mediated by Eosinophil Peroxidase

Forbes, E., Murase, T., Yang, M., Matthaei, K. I., Lee, J. J., Lee, N. A., Foster, P. S. & Hogan, S. P., May 1 2004, In : Journal of Immunology. 172, 9, p. 5664-5675 12 p.

Research output: Contribution to journalArticle

Eosinophil Peroxidase
Ulcerative Colitis
Eosinophils
Colon
Dextran Sulfate
20 Citations (Scopus)
Mucin-1
Fatty Acids
Cholesterol
Intestinal Absorption
Messenger RNA