Biochemistry and Molecular Biology

Research Output

Research Output per year

1975 2021

• 621 Article
• 40 Review article
• 10 Chapter
• 8 Comment/debate
• 8 More
  • 3 Letter
  • 2 Conference contribution
  • 2 Short survey
  • 1 Book

Research Output per year

Research Output per year

Search results

• 2012

  Detection of Progressive Myocardial Tissue Injury by Ultrasonic Integrated Backscatter Immediately After Coronary Reperfusion

  Katayama, M., Jiamsripong, P., McMahon, E. M., Lombari, T. R., Bukatina, A. E., Wu, Q., Marler, R. J. & Belohlavek, M., Sep 2012, In: Ultrasound in Medicine and Biology. 38, 9, p. 1662-1669 8 p.

  Research output: Contribution to journal › Article › peer-review

  • ischemia
  • Myocardial Reperfusion
  • Ultrasonics
  • ultrasonics
  • Ischemia
  1 Scopus citations

• Differential sensitivity of types 1 and 2 cholecystokinin receptors to membrane cholesterol

  Potter, R. M., Harikumar, K. G., Wu, S. V. & Miller, L. J., Jan 2012, In: Journal of Lipid Research. 53, 1, p. 137-148 12 p.

  Research output: Contribution to journal › Article › peer-review

  • Cholecystokinin B Receptor
  • Membranes
  • Cholesterol
  • G-Protein-Coupled Receptors
  • Signal transduction
  30 Scopus citations

• Elevated expression of Fn14 in non-small cell lung cancer correlates with activated EGFR and promotes tumor cell migration and invasion

  Whitsett, T. G., Cheng, E., Inge, L., Asrani, K., Jameson, N. M., Hostetter, G., Weiss, G. J., Kingsley, C. B., Loftus, J. C., Bremner, R., Tran, N. L. & Winkles, J. A., Jul 2012, In: American Journal of Pathology. 181, 1, p. 111-120 10 p.

  Research output: Contribution to journal › Article › peer-review

  • ErbB Receptors
  • Non-Small Cell Lung Carcinoma
  • Cell Movement
  • Protein-Tyrosine Kinases
  • Neoplasms
  37 Scopus citations

• Eosinophilic esophagitis: Epithelial mesenchymal transition contributes to esophageal remodeling and reverses with treatment

  Kagalwalla, A. F., Akhtar, N., Woodruff, S. A., Rea, B. A., Masterson, J. C., Mukkada, V., Parashette, K. R., Du, J., Fillon, S., Protheroe, C. A., Lee, J. J., Amsden, K., Melin-Aldana, H., Capocelli, K. E., Furuta, G. T. & Ackerman, S. J., May 2012, In: Journal of Allergy and Clinical Immunology. 129, 5, p. 1387-1396.e6

  Research output: Contribution to journal › Article › peer-review

  • Eosinophilic Esophagitis
  • Epithelial-Mesenchymal Transition
  • Eosinophils
  • Eosinophil Peroxidase
  • Fibrosis
  129 Scopus citations

• Eosinophils preserve parasitic nematode larvae by regulating local immunity

  Gebreselassie, N. G., Moorhead, A. R., Fabre, V., Gagliardo, L. F., Lee, N. A., Lee, J. J. & Appleton, J. A., Jan 1 2012, In: Journal of Immunology. 188, 1, p. 417-425 9 p.

  Research output: Contribution to journal › Article › peer-review

  • Larva
  • Eosinophils
  • Immunity
  • Trichinella spiralis
  • Nitric Oxide Synthase
  63 Scopus citations

• Expression of wild-type and mutant S20G hIAPP in physiologic knock-in mouse models fails to induce islet amyloid formation, but induces mild glucose intolerance

  Hiddinga, H. J., Sakagashira, S., Ishigame, M., Madde, P., Sanke, T., Nanjo, K., Kudva, Y. C., Lee, J. J., van Deursen, J. & Eberhardt, N. L., Apr 2012, In: Journal of Diabetes Investigation. 3, 2, p. 138-147 10 p.

  Research output: Contribution to journal › Article › peer-review

  • Glucose Intolerance
  • Amyloid
  • Type 2 Diabetes Mellitus
  • Alleles
  • Diet
  7 Scopus citations

• Force fields for homology modeling

  Bordner, A. J., Mar 16 2012, Homology Modeling: Methods and Protocols. Orry, A. & Abagyan, R. (eds.). p. 83-106 24 p. (Methods in Molecular Biology; vol. 857).

  Research output: Chapter in Book/Report/Conference proceeding › Chapter

  • Proteins
  • Physics
  • Membranes
  6 Scopus citations

• Glucagon-like peptide-1 receptor dimerization differentially regulates agonist signaling but does not affect small molecule allostery

  Harikumar, K. G., Wootten, D., Pinon, D. I., Koole, C., Ball, A. M., Furness, S. G. B., Graham, B., Dong, M., Christopoulos, A., Miller, L. J. & Sexton, P. M., Nov 6 2012, In: Proceedings of the National Academy of Sciences of the United States of America. 109, 45, p. 18607-18612 6 p.

  Research output: Contribution to journal › Article › peer-review

  • Glucagon-Like Peptide-1 Receptor
  • Dimerization
  • Peptides
  • Ligands
  • Phosphorylation
  44 Scopus citations

• Human breast cancer stem cells have significantly higher rate of clathrin-independent and caveolin-independent endocytosis than the differentiated breast cancer cells

  Palaniyandi, K., Pockaj, B. A., Gendler, S. J. & Chang, X. B., 2012, In: Journal of Cancer Science and Therapy. 4, 7, p. 214-222 9 p.

  Research output: Contribution to journal › Article › peer-review

  • Caveolins
  • Clathrin
  • Neoplastic Stem Cells
  • Endocytosis
  • Breast Neoplasms
  14 Scopus citations

• Human versus mouse eosinophils: "That which we call an eosinophil, by any other name would stain as red"

  Lee, J. J., Jacobsen, E. A., Ochkur, S. I., McGarry, M. P., Condjella, R. M., Doyle, A. D., Luo, H., Zellner, K. R., Protheroe, C. A., Willetts, L., Lesuer, W. E., Colbert, D. C., Helmers, R. A., Lacy, P., Moqbel, R. & Lee, N. A., Sep 2012, In: Journal of Allergy and Clinical Immunology. 130, 3, p. 572-584 13 p.

  Research output: Contribution to journal › Review article › peer-review

  • Eosinophils
  • Names
  • Coloring Agents
  • Research Subjects
  • Genome
  105 Scopus citations

• Immune recognition of tumor-associated mucin MUC1 is achieved by a fully synthetic aberrantly glycosylated MUC1 tripartite vaccine

  Lakshminarayanan, V., Thompson, P., Wolfert, M. A., Buskas, T., Bradley, J. M., Pathangey, L. B., Madsen, C. S., Cohen, P. A., Gendler, S. J. & Boons, G. J., Jan 3 2012, In: Proceedings of the National Academy of Sciences of the United States of America. 109, 1, p. 261-266 6 p.

  Research output: Contribution to journal › Article › peer-review

  • Mucins
  • Cytotoxic T-Lymphocytes
  • Vaccines
  • Antibody-Dependent Cell Cytotoxicity
  • Peptides
  207 Scopus citations

• Interleukin 5 is protective during sepsis in an eosinophil-independent manner

  Linch, S. N., Danielson, E. T., Kelly, A. M., Tamakawa, R. A., Lee, J. J. & Gold, J. A., Aug 1 2012, In: American journal of respiratory and critical care medicine. 186, 3, p. 246-254 9 p.

  Research output: Contribution to journal › Article › peer-review

  • Interleukin-5
  • Eosinophils
  • Sepsis
  • Interleukin-5 Receptors
  • Monocytes
  40 Scopus citations

• Intratumoral delivery of CpG-conjugated anti-MUC1 antibody enhances NK cell anti-tumor activity

  Schettini, J., Kidiyoor, A., Besmer, D. M., Tinder, T. L., Roy, L. D., Lustgarten, J., Gendler, S. J. & Mukherjee, P., Nov 2012, In: Cancer Immunology, Immunotherapy. 61, 11, p. 2055-2065 11 p.

  Research output: Contribution to journal › Article › peer-review

  • Natural Killer Cells
  • Oligodeoxyribonucleotides
  • Anti-Idiotypic Antibodies
  • Neoplasms
  • Pancreatic Neoplasms
  21 Scopus citations

• Ligand binding and activation of the secretin receptor, a prototypic family B G protein-coupled receptor

  Miller, L. J., Dong, M. & Harikumar, K. G., May 2012, In: British Journal of Pharmacology. 166, 1, p. 18-26 9 p.

  Research output: Contribution to journal › Review article › peer-review

  • secretin receptor
  • G-Protein-Coupled Receptors
  • Ligands
  • Peptides
  • Secretin
  14 Scopus citations

• Ligand-induced internalization of the type 1 cholecystokinin receptor independent of recognized signaling activity

  Cawston, E. E., Harikumar, K. G. & Miller, L. J., Feb 2012, In: American Journal of Physiology - Cell Physiology. 302, 3, p. C615-C627

  Research output: Contribution to journal › Article › peer-review

  • tyrosyl-glycyl-(norleucyl(28.31)-tryptophyl(30))-cholecystokinin (26-32) phenylethyl ester
  • Cholecystokinin Receptors
  • Cholecystokinin
  • Ligands
  • Peptides
  3 Scopus citations

• MiRNA expression profiling in migrating Glioblastoma cells: Regulation of cell migration and invasion by miR-23b via targeting of Pyk2

  Loftus, J. C., Ross, J. T. D., Paquette, K. M., Paulino, V. M., Nasser, S., Yang, Z., Kloss, J., Kim, S., Berens, M. E. & Tran, N. L., Jun 22 2012, In: PloS one. 7, 6, e39818.

  Research output: Contribution to journal › Article › peer-review

  • glioblastoma
  • glioma
  • cell movement
  • Glioblastoma
  • Cells
  51 Scopus citations

• Modulation of β-catenin signaling by glucagon receptor activation

  Ke, J., Zhang, C., Harikumar, K. G., Zylstra-Diegel, C. R., Wang, L., Mowry, L. E., Miller, L. J., Williams, B. O. & Xu, H. E., Mar 16 2012, In: PloS one. 7, 3, e33676.

  Research output: Contribution to journal › Article › peer-review

  • glucagon receptors
  • catenins
  • Glucagon Receptors
  • Low Density Lipoprotein Receptor-Related Protein-5
  • Catenins
  13 Scopus citations

• Molecular basis for binding and subtype selectivity of 1,4-benzodiazepine antagonist ligands of the cholecystokinin receptor

  Cawston, E. E., Lam, P. C. H., Harikumar, K. G., Dong, M., Ball, A. M., Augustine, M. L., Akgün, E., Portoghese, P. S., Orry, A., Abagyan, R., Sexton, P. M. & Miller, L. J., May 25 2012, In: Journal of Biological Chemistry. 287, 22, p. 18618-18635 18 p.

  Research output: Contribution to journal › Article › peer-review

  • Bz-423
  • Cholecystokinin Receptors
  • Ligands
  • Stereochemistry
  • Benzodiazepines
  15 Scopus citations

• MUC1 regulates PDGFA expression during pancreatic cancer progression

  Sahraei, M., Roy, L. D., Curry, J. M., Teresa, T. L., Nath, S., Besmer, D., Kidiyoor, A., Dalia, R., Gendler, S. J. & Mukherjee, P., Nov 22 2012, In: Oncogene. 31, 47, p. 4935-4945 11 p.

  Research output: Contribution to journal › Article › peer-review

  • platelet-derived growth factor A
  • Mucin-1
  • Pancreatic Neoplasms
  • Adenocarcinoma
  • Carcinogenesis
  45 Scopus citations

• Myeloid-derived suppressor cells adhere to physiologic STAT3-vs STAT5-dependent hematopoietic programming, establishing diverse tumor-mediated mechanisms of immunologic escape

  Cohen, P. A., Ko, J. S., Storkus, W. J., Spencer, C. D., Bradley, J. M., Gorman, J. E., McCurry, D. B., Zorro-Manrique, S., Dominguez, A. L., Pathangey, L. B., Rayman, P. A., Rini, B. I., Gendler, S. J. & Finke, J. H., Aug 2012, In: Immunological Investigations. 41, 6-7, p. 680-710 31 p.

  Research output: Contribution to journal › Article › peer-review

  • Myeloid-Derived Suppressor Cells
  • Sunitinib
  • Neoplasms
  • Granulocyte-Macrophage Colony-Stimulating Factor
  • preempt
  30 Scopus citations

• PHF20 is an effector protein of p53 double lysine methylation that stabilizes and activates p53

  Cui, G., Park, S., Badeaux, A. I., Kim, D., Lee, J., Thompson, J. R., Yan, F., Kaneko, S., Yuan, Z., Botuyan, M. V., Bedford, M. T., Cheng, J. Q. & Mer, G., Sep 2012, In: Nature Structural and Molecular Biology. 19, 9, p. 916-924 9 p.

  Research output: Contribution to journal › Article › peer-review

  • Tudor Domain
  • Lysine
  • Methylation
  • Lysine Acetyltransferases
  • Protein Subunits
  56 Scopus citations

• Placental protein 13 and decidual zones of necrosis: An immunologic diversion that may be linked to preeclampsia

  Kliman, H. J., Sammar, M., Grimpel, Y. I., Lynch, S. K., Milano, K. M., Pick, E., Bejar, J., Arad, A., Lee, J. J., Meiri, H. & Gonen, R., Jan 1 2012, In: Reproductive Sciences. 19, 1, p. 16-30 15 p.

  Research output: Contribution to journal › Article › peer-review

  • Pregnancy Proteins
  • Trophoblasts
  • Pre-Eclampsia
  • Necrosis
  • Arterioles
  49 Scopus citations

• Predicting the effects of amino acid replacements in peptide hormones on their binding affinities for class B GPCRs and application to the design of secretin receptor antagonists

  Te, J. A., Dong, M., Miller, L. J. & Bordner, A. J., Jul 2012, In: Journal of Computer-Aided Molecular Design. 26, 7, p. 835-845 11 p.

  Research output: Contribution to journal › Article › peer-review

  • Secretin
  • Peptide Hormones
  • secretin receptor
  • hormones
  • Peptides
  3 Scopus citations

• Protein tyrosine phosphatase SHP2 regulates TGF-β1 production in airway epithelia and asthmatic airway remodeling in mice

  Qin, X. J., Zhang, G. S., Zhang, X., Qiu, Z. W., Wang, P. L., Li, Y. W., Li, W., Xie, Q. M., Ke, Y. H., Lee, J. J. & Shen, H. H., Dec 2012, In: Allergy: European Journal of Allergy and Clinical Immunology. 67, 12, p. 1547-1556 10 p.

  Research output: Contribution to journal › Article › peer-review

  • Airway Remodeling
  • Protein Tyrosine Phosphatases
  • Transforming Growth Factors
  • Epithelium
  • Ovalbumin
  27 Scopus citations

• The construction of transgenic and gene knockout/knockin mouse models of human disease

  Doyle, A., McGarry, M. P., Lee, N. A. & Lee, J. J., Apr 2012, In: Transgenic Research. 21, 2, p. 327-349 23 p.

  Research output: Contribution to journal › Review article › peer-review

  • Gene Knockout Techniques
  • human diseases
  • gene targeting
  • Knockout Mice
  • animal models
  99 Scopus citations

• The development of a sensitive and specific ELISA for mouse eosinophil peroxidase: Assessment of eosinophil degranulation ex vivo and in models of human disease

  Ochkur, S. I., Kim, J. D., Protheroe, C. A., Colbert, D., Moqbel, R., Lacy, P., Lee, J. J. & Lee, N. A., Jan 31 2012, In: Journal of Immunological Methods. 375, 1-2, p. 138-147 10 p.

  Research output: Contribution to journal › Article › peer-review

  • Eosinophil Peroxidase
  • Eosinophils
  • Enzyme-Linked Immunosorbent Assay
  • Eosinophil Granule Proteins
  • Platelet Activating Factor
  32 Scopus citations

• The expanding role(s) of eosinophils in health and disease

  Jacobsen, E. A., Helmers, R. A., Lee, J. J. & Lee, N. A., Nov 8 2012, In: Blood. 120, 19, p. 3882-3890 9 p.

  Research output: Contribution to journal › Review article › peer-review

  • Eosinophils
  • Health
  • Cells
  • Blood
  • Granulocytes
  118 Scopus citations

• Workshop report from the national institutes of health taskforce on the research needs of eosinophil-associated diseases (TREAD)

  Bochner, B. S., Book, W., Busse, W. W., Butterfield, J., Furuta, G. T., Gleich, G. J., Klion, A. D., Lee, J. J., Leiferman, K. M., Minnicozzi, M., Moqbel, R., Rothenberg, M. E., Schwartz, L. B., Simon, H. U., Wechsler, M. E. & Weller, P. F., Sep 2012, In: Journal of Allergy and Clinical Immunology. 130, 3, p. 587-596 10 p.

  Research output: Contribution to journal › Article › peer-review

  • National Institutes of Health (U.S.)
  • Eosinophils
  • Education
  • Patient Advocacy
  • Drug Industry
  36 Scopus citations
• 2011

  CCR3 blockade attenuates eosinophilic ileitis and associated remodeling

  Masterson, J. C., McNamee, E. N., Jedlicka, P., Fillon, S., Ruybal, J., Hosford, L., Rivera-Nieves, J., Lee, J. J. & Furuta, G. T., Nov 2011, In: American Journal of Pathology. 179, 5, p. 2302-2314 13 p.

  Research output: Contribution to journal › Article › peer-review

  • Ileitis
  • Eosinophils
  • Inflammatory Bowel Diseases
  • Fibronectins
  • Goblet Cells
  30 Scopus citations

• Cereblon expression is required for the antimyeloma activity of lenalidomide and pomalidomide

  Zhu, Y. X., Braggio, E., Shi, C. X., Bruins, L. A., Schmidt, J. E., Van Wier, S., Chang, X. B., Bjorklund, C. C., Fonseca, R., Bergsagel, P. L., Orlowski, R. Z. & Stewart, A. K., Nov 3 2011, In: Blood. 118, 18, p. 4771-4779 9 p.

  Research output: Contribution to journal › Article › peer-review

  • pomalidomide
  • Lenalidomide
  • Thalidomide
  • interferon regulatory factor-4
  • Biomarkers
  387 Scopus citations

• Core-glycosylated mucin-like repeats from MUC1 are an apical targeting signal

  Kinlough, C. L., Poland, P. A., Gendler, S. J., Mattila, P. E., Mo, D., Weisz, O. A. & Hughey, R. P., Nov 11 2011, In: Journal of Biological Chemistry. 286, 45, p. 39072-39081 10 p.

  Research output: Contribution to journal › Article › peer-review

  • Mucins
  • Polysaccharides
  • Madin Darby Canine Kidney Cells
  • poly-N-acetyllactosamine
  • Lectins
  24 Scopus citations

• Efficient molecular mechanics simulations of the folding, orientation, and assembly of peptides in lipid bilayers using an implicit atomic solvation model

  Bordner, A. J., Zorman, B. & Abagyan, R., Oct 2011, In: Journal of Computer-Aided Molecular Design. 25, 10, p. 895-911 17 p.

  Research output: Contribution to journal › Article › peer-review

  • Lipid bilayers
  • Solvation
  • Molecular mechanics
  • Peptides
  • Lipid Bilayers
  3 Scopus citations

• Eosinophilic oesophagitis in adults - A rising epidemic

  Pasha, S. F., Crowell, M. D., Alexander, J. A., Harris, L. A., Achem, S. R., Farrugia, G., Lee, J. J., Thompson, D. M., Jung, K. W., Kita, H., Ravi, K., Namasivayam, V., Kim, H. J., Fleischer, D. E., Sharma, V. K. & Romero, Y., Feb 2011, In: European Gastroenterology and Hepatology Review. 7, 1, p. 14-20 7 p.

  Research output: Contribution to journal › Review article › peer-review

  • Eosinophilic Esophagitis
  • Epidemics
  • Allergens
  • Esophagus
  • Esophageal Mucosa
  1 Scopus citations

• Eosinophils

  Lee, N. A., Dahl, M. V., Jacobsen, E. A. & Ochkur, S. I., Jul 27 2011, Inflammation and Allergy Drug Design. Wiley-Blackwell, p. 107-121 15 p.

  Research output: Chapter in Book/Report/Conference proceeding › Chapter

• Eosinophils are necessary for pulmonary arterial remodeling in a mouse model of eosinophilic inflammation-induced pulmonary hypertension

  Weng, M., Baron, D. M., Bloch, K. D., Luster, A. D., Lee, J. J. & Medoff, B. D., Dec 2011, In: American Journal of Physiology - Lung Cellular and Molecular Physiology. 301, 6, p. L927-L936

  Research output: Contribution to journal › Article › peer-review

  • Vascular Remodeling
  • Pulmonary Hypertension
  • Eosinophils
  • Hypoadiponectinemia
  • Inflammation
  22 Scopus citations

• Eosinophils are required for the maintenance of plasma cells in the bone marrow

  Chu, V. T., Fröhlich, A., Steinhauser, G., Scheel, T., Roch, T., Fillatreau, S., Lee, J. J., Löhning, M. & Berek, C., Feb 2011, In: Nature immunology. 12, 2, p. 151-159 9 p.

  Research output: Contribution to journal › Article › peer-review

  • Plasma Cells
  • Eosinophils
  • Bone Marrow
  • Maintenance
  • Bone Marrow Cells
  327 Scopus citations

• Eosinophils increase neuron branching in human and murine skin and in vitro

  Foster, E. L., Simpson, E. L., Fredrikson, L. J., Lee, J. J., Lee, N. A., Fryer, A. D. & Jacoby, D. B., 2011, In: PloS one. 6, 7, e22029.

  Research output: Contribution to journal › Article › peer-review

  • Atopic Dermatitis
  • eosinophils
  • Eosinophils
  • branching
  • Neurons
  51 Scopus citations

• Eosinophils regulate dendritic cells and Th2 pulmonary immune responses following allergen provocation

  Jacobsen, E. A., Zellner, K. R., Colbert, D., Lee, N. A. & Lee, J. J., Dec 1 2011, In: Journal of Immunology. 187, 11, p. 6059-6068 10 p.

  Research output: Contribution to journal › Article › peer-review

  • Eosinophils
  • Allergens
  • Dendritic Cells
  • Lung
  • T-Lymphocytes
  81 Scopus citations

• Fluorescence polarization screening for allosteric small molecule ligands of the cholecystokinin receptor

  Harikumar, K. G., Cawston, E. E. & Miller, L. J., Aug 1 2011, In: Assay and Drug Development Technologies. 9, 4, p. 394-402 9 p.

  Research output: Contribution to journal › Article › peer-review

  • Cholecystokinin Receptors
  • Fluorescence Polarization
  • Ligands
  • Benzodiazepines
  • Benzoic Acid
  8 Scopus citations

• Glutamine residues in Q-loops of multidrug resistance protein MRP1 contribute to ATP binding via interaction with metal cofactor

  Yang, R., Hou, Y. X., Campbell, C. A., Palaniyandi, K., Zhao, Q., Bordner, A. J. & Chang, X. B., Jul 2011, In: Biochimica et Biophysica Acta - Biomembranes. 1808, 7, p. 1790-1796 7 p.

  Research output: Contribution to journal › Article › peer-review

  • Subfamily B ATP Binding Cassette Transporter
  • multidrug resistance-associated protein 1
  • Glutamine
  • Metals
  • Adenosine Triphosphate
  6 Scopus citations

• Immunodetection of occult eosinophils in lung tissue biopsies may help predict survival in acute lung injury

  Willetts, L., Parker, K., Wesselius, L. J., Protheroe, C. A., Jaben, E., Graziano, P., Moqbel, R., Leslie, K. O., Lee, N. A. & Lee, J. J., Aug 26 2011, In: Respiratory Research. 12, 116.

  Research output: Contribution to journal › Article › peer-review

  • Acute Lung Injury
  • Eosinophils
  • Biopsy
  • Survival
  • Lung
  22 Scopus citations

• Importance and regulation of the colonic mucus barrier in a mouse model of colitis

  Petersson, J., Schreiber, O., Hansson, G. C., Gendler, S. J., Velcich, A., Lundberg, J. O., Roos, S., Holm, L. & Phillipson, M., Feb 2011, In: American Journal of Physiology - Gastrointestinal and Liver Physiology. 300, 2, p. G327-G333

  Research output: Contribution to journal › Article › peer-review

  • Mucus
  • Colitis
  • Peptidoglycan
  • Lipopolysaccharides
  • Colon
  188 Scopus citations

• Importance of each residue within secretin for receptor binding and biological activity

  Dong, M., Le, A., Te, J. A., Pinon, D. I., Bordner, A. J. & Miller, L. J., Apr 12 2011, In: Biochemistry. 50, 14, p. 2983-2993 11 p.

  Research output: Contribution to journal › Article › peer-review

  • secretin receptor
  • Bioactivity
  • Secretin
  • Molecular Dynamics Simulation
  • Molecular dynamics
  21 Scopus citations

• Infection of H69AR cells with retroviral particles harboring interfering RNAi significantly reduced the multidrug resistance of these small cell lung cancer cells

  Palaniyandi, K., Zhao, Q. & Chang, X. B., Jun 10 2011, In: International Journal of Biochemistry and Molecular Biology. 2, 2, p. 155-167 13 p.

  Research output: Contribution to journal › Article › peer-review

  • multidrug resistance-associated protein 1
  • Small Cell Lung Carcinoma
  • Multiple Drug Resistance
  • Cells
  • RNA Interference
  6 Scopus citations

• Lactam constraints provide insights into the receptor-bound conformation of secretin and stabilize a receptor antagonist

  Dong, M., Te, J. A., Xu, X., Wang, J., Pinon, D. I., Storjohann, L., Bordner, A. J. & Miller, L. J., Sep 27 2011, In: Biochemistry. 50, 38, p. 8181-8192 12 p.

  Research output: Contribution to journal › Article › peer-review

  • Lactams
  • Conformations
  • Secretin
  • Peptides
  • Ligands
  16 Scopus citations

• Local proliferation and mobilization of CCR3⁺ CD34⁺ eosinophil-lineage-committed cells in the lung

  Rådinger, M., Bossios, A., Sjöstrand, M., Lu, Y., Malmhäll, C., Dahlborn, A. K., Lee, J. J. & Lötvall, J., Jan 2011, In: Immunology. 132, 1, p. 144-154 11 p.

  Research output: Contribution to journal › Article › peer-review

  • Eosinophils
  • Allergens
  • Chemokine CCL24
  • Lung
  • Interleukin-5
  24 Scopus citations

• Major basic protein from eosinophils and myeloperoxidase from neutrophils are required for protective immunity to Strongyloides stercoralis in mice

  O'Connell, A. E., Hess, J. A., Santiago, G. A., Nolan, T. J., Lok, J. B., Lee, J. J. & Abraham, D., Jul 2011, In: Infection and Immunity. 79, 7, p. 2770-2778 9 p.

  Research output: Contribution to journal › Article › peer-review

  • Eosinophil Major Basic Protein
  • Strongyloides stercoralis
  • Eosinophils
  • Peroxidase
  • Immunity
  68 Scopus citations

• MUC1 enhances invasiveness of pancreatic cancer cells by inducing epithelial to mesenchymal transition

  Roy, L. D., Sahraei, M., Subramani, D. B., Besmer, D., Nath, S., Tinder, T. L., Bajaj, E., Shanmugam, K., Lee, Y. Y., Hwang, S. I. L., Gendler, S. J. & Mukherjee, P., Mar 24 2011, In: Oncogene. 30, 12, p. 1449-1459 11 p.

  Research output: Contribution to journal › Article › peer-review

  • Epithelial-Mesenchymal Transition
  • Pancreatic Neoplasms
  • Cadherins
  • Gastropoda
  • Catenins
  168 Scopus citations

• Pancreatic ductal adenocarcinoma mice lacking mucin 1 have a profound defect in tumor growth and metastasis

  Besmer, D. M., Curry, J. M., Roy, L. D., Tinder, T. L., Sahraei, M., Schettini, J., Hwang, S. I., Lee, Y. Y., Gendler, S. J. & Mukherjee, P., Jul 1 2011, In: Cancer research. 71, 13, p. 4432-4442 11 p.

  Research output: Contribution to journal › Article › peer-review

  • Mucin-1
  • Adenocarcinoma
  • Neoplasm Metastasis
  • Growth
  • Mitogen-Activated Protein Kinases
  84 Scopus citations

• Recombinant plant-expressed tumour-associated MUC1 peptide is immunogenic and capable of breaking tolerance in MUC1.Tg mice

  Pinkhasov, J., Alvarez, M. L., Rigano, M. M., Piensook, K., Larios, D., Pabst, M., Grass, J., Mukherjee, P., Gendler, S. J., Walmsley, A. M. & Mason, H. S., Dec 2011, In: Plant Biotechnology Journal. 9, 9, p. 991-1001 11 p.

  Research output: Contribution to journal › Article › peer-review

  • Plant Tumors
  • tandem repeat sequences
  • MUC1 tandem repeat peptide
  • neoplasms
  • antigens
  34 Scopus citations