Research Output per year
Research Output
2012
Ligand binding and activation of the secretin receptor, a prototypic family B G protein-coupled receptor
Miller, L. J., Dong, M. & Harikumar, K. G., May 1 2012, In : British Journal of Pharmacology. 166, 1, p. 18-26 9 p.Research output: Contribution to journal › Review article
11
Scopus
citations
Ligand-induced internalization of the type 1 cholecystokinin receptor independent of recognized signaling activity
Cawston, E. E., Harikumar, K. G. & Miller, L. J., Feb 1 2012, In : American Journal of Physiology - Cell Physiology. 302, 3, p. C615-C627Research output: Contribution to journal › Article
2
Scopus
citations
MiRNA expression profiling in migrating Glioblastoma cells: Regulation of cell migration and invasion by miR-23b via targeting of Pyk2
Loftus, J. C., Ross, J. T. D., Paquette, K. M., Paulino, V. M., Nasser, S., Yang, Z., Kloss, J., Kim, S., Berens, M. E. & Tran, N. L., Jun 22 2012, In : PloS one. 7, 6, e39818.Research output: Contribution to journal › Article
49
Scopus
citations
Modulation of β-catenin signaling by glucagon receptor activation
Ke, J., Zhang, C., Harikumar, K. G., Zylstra-Diegel, C. R., Wang, L., Mowry, L. E., Miller, L. J., Williams, B. O. & Xu, H. E., Mar 16 2012, In : PloS one. 7, 3, e33676.Research output: Contribution to journal › Article
13
Scopus
citations
Molecular basis for binding and subtype selectivity of 1,4-benzodiazepine antagonist ligands of the cholecystokinin receptor
Cawston, E. E., Lam, P. C. H., Harikumar, K. G., Dong, M., Ball, A. M., Augustine, M. L., Akgün, E., Portoghese, P. S., Orry, A., Abagyan, R., Sexton, P. M. & Miller, L. J., May 25 2012, In : Journal of Biological Chemistry. 287, 22, p. 18618-18635 18 p.Research output: Contribution to journal › Article
14
Scopus
citations
MUC1 regulates PDGFA expression during pancreatic cancer progression
Sahraei, M., Roy, L. D., Curry, J. M., Teresa, T. L., Nath, S., Besmer, D., Kidiyoor, A., Dalia, R., Gendler, S. J. & Mukherjee, P., Nov 22 2012, In : Oncogene. 31, 47, p. 4935-4945 11 p.Research output: Contribution to journal › Article
36
Scopus
citations
Myeloid-derived suppressor cells adhere to physiologic STAT3-vs STAT5-dependent hematopoietic programming, establishing diverse tumor-mediated mechanisms of immunologic escape
Cohen, P. A., Ko, J. S., Storkus, W. J., Spencer, C. D., Bradley, J. M., Gorman, J. E., McCurry, D. B., Zorro-Manrique, S., Dominguez, A. L., Pathangey, L. B., Rayman, P. A., Rini, B. I., Gendler, S. J. & Finke, J. H., Aug 1 2012, In : Immunological Investigations. 41, 6-7, p. 680-710 31 p.Research output: Contribution to journal › Article
29
Scopus
citations
PHF20 is an effector protein of p53 double lysine methylation that stabilizes and activates p53
Cui, G., Park, S., Badeaux, A. I., Kim, D., Lee, J., Thompson, J. R., Yan, F., Kaneko, S., Yuan, Z., Botuyan, M. V., Bedford, M. T., Cheng, J. Q. & Mer, G., Sep 1 2012, In : Nature Structural and Molecular Biology. 19, 9, p. 916-924 9 p.Research output: Contribution to journal › Article
49
Scopus
citations
Placental protein 13 and decidual zones of necrosis: An immunologic diversion that may be linked to preeclampsia
Kliman, H. J., Sammar, M., Grimpel, Y. I., Lynch, S. K., Milano, K. M., Pick, E., Bejar, J., Arad, A., Lee, J. J., Meiri, H. & Gonen, R., Jan 1 2012, In : Reproductive Sciences. 19, 1, p. 16-30 15 p.Research output: Contribution to journal › Article
46
Scopus
citations
Predicting the effects of amino acid replacements in peptide hormones on their binding affinities for class B GPCRs and application to the design of secretin receptor antagonists
Te, J. A., Dong, M., Miller, L. J. & Bordner, A. J., Jul 1 2012, In : Journal of Computer-Aided Molecular Design. 26, 7, p. 835-845 11 p.Research output: Contribution to journal › Article
3
Scopus
citations
Protein tyrosine phosphatase SHP2 regulates TGF-β1 production in airway epithelia and asthmatic airway remodeling in mice
Qin, X. J., Zhang, G. S., Zhang, X., Qiu, Z. W., Wang, P. L., Li, Y. W., Li, W., Xie, Q. M., Ke, Y. H., Lee, J. J. & Shen, H. H., Dec 1 2012, In : Allergy: European Journal of Allergy and Clinical Immunology. 67, 12, p. 1547-1556 10 p.Research output: Contribution to journal › Article
25
Scopus
citations
The construction of transgenic and gene knockout/knockin mouse models of human disease
Doyle, A., McGarry, M. P., Lee, N. A. & Lee, J. J., Apr 1 2012, In : Transgenic Research. 21, 2, p. 327-349 23 p.Research output: Contribution to journal › Review article
89
Scopus
citations
The development of a sensitive and specific ELISA for mouse eosinophil peroxidase: Assessment of eosinophil degranulation ex vivo and in models of human disease
Ochkur, S. I., Kim, J. D., Protheroe, C. A., Colbert, D., Moqbel, R., Lacy, P., Lee, J. J. & Lee, N. A., Jan 31 2012, In : Journal of Immunological Methods. 375, 1-2, p. 138-147 10 p.Research output: Contribution to journal › Article
28
Scopus
citations
The expanding role(s) of eosinophils in health and disease
Jacobsen, E. A., Helmers, R. A., Lee, J. J. & Lee, N. A., Nov 8 2012, In : Blood. 120, 19, p. 3882-3890 9 p.Research output: Contribution to journal › Review article
103
Scopus
citations
Workshop report from the national institutes of health taskforce on the research needs of eosinophil-associated diseases (TREAD)
Bochner, B. S., Book, W., Busse, W. W., Butterfield, J., Furuta, G. T., Gleich, G. J., Klion, A. D., Lee, J. J., Leiferman, K. M., Minnicozzi, M., Moqbel, R., Rothenberg, M. E., Schwartz, L. B., Simon, H. U., Wechsler, M. E. & Weller, P. F., Sep 1 2012, In : Journal of Allergy and Clinical Immunology. 130, 3, p. 587-596 10 p.Research output: Contribution to journal › Article
36
Scopus
citations
2011
CCR3 blockade attenuates eosinophilic ileitis and associated remodeling
Masterson, J. C., McNamee, E. N., Jedlicka, P., Fillon, S., Ruybal, J., Hosford, L., Rivera-Nieves, J., Lee, J. J. & Furuta, G. T., Nov 1 2011, In : American Journal of Pathology. 179, 5, p. 2302-2314 13 p.Research output: Contribution to journal › Article
27
Scopus
citations
Cereblon expression is required for the antimyeloma activity of lenalidomide and pomalidomide
Zhu, Y. X., Braggio, E., Shi, C. X., Bruins, L. A., Schmidt, J. E., Van Wier, S., Chang, X. B., Bjorklund, C. C., Fonseca, R., Bergsagel, P. L., Orlowski, R. Z. & Stewart, A. K., Nov 3 2011, In : Blood. 118, 18, p. 4771-4779 9 p.Research output: Contribution to journal › Article
367
Scopus
citations
Core-glycosylated mucin-like repeats from MUC1 are an apical targeting signal
Kinlough, C. L., Poland, P. A., Gendler, S. J., Mattila, P. E., Mo, D., Weisz, O. A. & Hughey, R. P., Nov 11 2011, In : Journal of Biological Chemistry. 286, 45, p. 39072-39081 10 p.Research output: Contribution to journal › Article
22
Scopus
citations
Efficient molecular mechanics simulations of the folding, orientation, and assembly of peptides in lipid bilayers using an implicit atomic solvation model
Bordner, A. J., Zorman, B. & Abagyan, R., Oct 1 2011, In : Journal of Computer-Aided Molecular Design. 25, 10, p. 895-911 17 p.Research output: Contribution to journal › Article
3
Scopus
citations
Eosinophilic oesophagitis in adults - A rising epidemic
Pasha, S. F., Crowell, M. D., Alexander, J. A., Harris, L. A., Achem, S. R., Farrugia, G., Lee, J. J., Thompson, D. M., Jung, K. W., Kita, H., Ravi, K., Namasivayam, V., Kim, H. J., Fleischer, D. E., Sharma, V. K. & Romero, Y., Feb 2011, In : European Gastroenterology and Hepatology Review. 7, 1, p. 14-20 7 p.Research output: Contribution to journal › Review article
1
Scopus
citations
Eosinophils
Lee, N. A., Dahl, M. V., Jacobsen, E. A. & Ochkur, S. I., Jul 27 2011, Inflammation and Allergy Drug Design. Wiley-Blackwell, p. 107-121 15 p.Research output: Chapter in Book/Report/Conference proceeding › Chapter
Eosinophils are necessary for pulmonary arterial remodeling in a mouse model of eosinophilic inflammation-induced pulmonary hypertension
Weng, M., Baron, D. M., Bloch, K. D., Luster, A. D., Lee, J. J. & Medoff, B. D., Dec 1 2011, In : American Journal of Physiology - Lung Cellular and Molecular Physiology. 301, 6, p. L927-L936Research output: Contribution to journal › Article
21
Scopus
citations
Eosinophils are required for the maintenance of plasma cells in the bone marrow
Chu, V. T., Fröhlich, A., Steinhauser, G., Scheel, T., Roch, T., Fillatreau, S., Lee, J. J., Löhning, M. & Berek, C., Feb 1 2011, In : Nature immunology. 12, 2, p. 151-159 9 p.Research output: Contribution to journal › Article
300
Scopus
citations
Eosinophils increase neuron branching in human and murine skin and in vitro
Foster, E. L., Simpson, E. L., Fredrikson, L. J., Lee, J. J., Lee, N. A., Fryer, A. D. & Jacoby, D. B., Jul 27 2011, In : PloS one. 6, 7, e22029.Research output: Contribution to journal › Article
48
Scopus
citations
Eosinophils regulate dendritic cells and Th2 pulmonary immune responses following allergen provocation
Jacobsen, E. A., Zellner, K. R., Colbert, D., Lee, N. A. & Lee, J. J., Dec 1 2011, In : Journal of Immunology. 187, 11, p. 6059-6068 10 p.Research output: Contribution to journal › Article
77
Scopus
citations
Fluorescence polarization screening for allosteric small molecule ligands of the cholecystokinin receptor
Harikumar, K. G., Cawston, E. E. & Miller, L. J., Aug 1 2011, In : Assay and Drug Development Technologies. 9, 4, p. 394-402 9 p.Research output: Contribution to journal › Article
8
Scopus
citations
Glutamine residues in Q-loops of multidrug resistance protein MRP1 contribute to ATP binding via interaction with metal cofactor
Yang, R., Hou, Y. X., Campbell, C. A., Palaniyandi, K., Zhao, Q., Bordner, A. J. & Chang, X. B., Jul 1 2011, In : Biochimica et Biophysica Acta - Biomembranes. 1808, 7, p. 1790-1796 7 p.Research output: Contribution to journal › Article
4
Scopus
citations
Immunodetection of occult eosinophils in lung tissue biopsies may help predict survival in acute lung injury
Willetts, L., Parker, K., Wesselius, L. J., Protheroe, C. A., Jaben, E., Graziano, P., Moqbel, R., Leslie, K. O., Lee, N. A. & Lee, J. J., Aug 26 2011, In : Respiratory Research. 12, 116.Research output: Contribution to journal › Article
18
Scopus
citations
Importance and regulation of the colonic mucus barrier in a mouse model of colitis
Petersson, J., Schreiber, O., Hansson, G. C., Gendler, S. J., Velcich, A., Lundberg, J. O., Roos, S., Holm, L. & Phillipson, M., Feb 1 2011, In : American Journal of Physiology - Gastrointestinal and Liver Physiology. 300, 2, p. G327-G333Research output: Contribution to journal › Article
178
Scopus
citations
Importance of each residue within secretin for receptor binding and biological activity
Dong, M., Le, A., Te, J. A., Pinon, D. I., Bordner, A. J. & Miller, L. J., Apr 12 2011, In : Biochemistry. 50, 14, p. 2983-2993 11 p.Research output: Contribution to journal › Article
20
Scopus
citations
Infection of H69AR cells with retroviral particles harboring interfering RNAi significantly reduced the multidrug resistance of these small cell lung cancer cells
Palaniyandi, K., Zhao, Q. & Chang, X. B., Jun 10 2011, In : International Journal of Biochemistry and Molecular Biology. 2, 2, p. 155-167 13 p.Research output: Contribution to journal › Article
6
Scopus
citations
Lactam constraints provide insights into the receptor-bound conformation of secretin and stabilize a receptor antagonist
Dong, M., Te, J. A., Xu, X., Wang, J., Pinon, D. I., Storjohann, L., Bordner, A. J. & Miller, L. J., Sep 27 2011, In : Biochemistry. 50, 38, p. 8181-8192 12 p.Research output: Contribution to journal › Article
15
Scopus
citations
Local proliferation and mobilization of CCR3+ CD34+ eosinophil-lineage-committed cells in the lung
Rådinger, M., Bossios, A., Sjöstrand, M., Lu, Y., Malmhäll, C., Dahlborn, A. K., Lee, J. J. & Lötvall, J., Jan 1 2011, In : Immunology. 132, 1, p. 144-154 11 p.Research output: Contribution to journal › Article
23
Scopus
citations
Major basic protein from eosinophils and myeloperoxidase from neutrophils are required for protective immunity to Strongyloides stercoralis in mice
O'Connell, A. E., Hess, J. A., Santiago, G. A., Nolan, T. J., Lok, J. B., Lee, J. J. & Abraham, D., Jul 1 2011, In : Infection and Immunity. 79, 7, p. 2770-2778 9 p.Research output: Contribution to journal › Article
61
Scopus
citations
MUC1 enhances invasiveness of pancreatic cancer cells by inducing epithelial to mesenchymal transition
Roy, L. D., Sahraei, M., Subramani, D. B., Besmer, D., Nath, S., Tinder, T. L., Bajaj, E., Shanmugam, K., Lee, Y. Y., Hwang, S. I. L., Gendler, S. J. & Mukherjee, P., Mar 24 2011, In : Oncogene. 30, 12, p. 1449-1459 11 p.Research output: Contribution to journal › Article
156
Scopus
citations
Pancreatic ductal adenocarcinoma mice lacking mucin 1 have a profound defect in tumor growth and metastasis
Besmer, D. M., Curry, J. M., Roy, L. D., Tinder, T. L., Sahraei, M., Schettini, J., Hwang, S. I., Lee, Y. Y., Gendler, S. J. & Mukherjee, P., Jul 1 2011, In : Cancer research. 71, 13, p. 4432-4442 11 p.Research output: Contribution to journal › Article
79
Scopus
citations
Recombinant plant-expressed tumour-associated MUC1 peptide is immunogenic and capable of breaking tolerance in MUC1.Tg mice
Pinkhasov, J., Alvarez, M. L., Rigano, M. M., Piensook, K., Larios, D., Pabst, M., Grass, J., Mukherjee, P., Gendler, S. J., Walmsley, A. M. & Mason, H. S., Dec 1 2011, In : Plant Biotechnology Journal. 9, 9, p. 991-1001 11 p.Research output: Contribution to journal › Article
33
Scopus
citations
The identification of eosinophilic gastroenteritis in prednisone-dependent eosinophilic bronchitis and asthma
Nair, P., Ochkur, S. I., Protheroe, C., Simms, E., Lee, N. A. & Lee, J. J., Mar 1 2011, In : Allergy, Asthma and Clinical Immunology. 7, 1, 4.Research output: Contribution to journal › Article
8
Scopus
citations
The Pyk2 FERM regulates Pyk2 complex formation and phosphorylation
Riggs, D., Yang, Z., Kloss, J. & Loftus, J. C., Jan 1 2011, In : Cellular Signalling. 23, 1, p. 288-296 9 p.Research output: Contribution to journal › Article
16
Scopus
citations
Update on clinical and immunological features of eosinophilic gastrointestinal diseases
Masterson, J. C., Furuta, G. T. & Lee, J. J., Oct 1 2011, In : Current Opinion in Gastroenterology. 27, 6, p. 515-522 8 p.Research output: Contribution to journal › Review article
29
Scopus
citations
What is the functional role of the thalidomide binding protein cereblon?
Chang, X. B. & Keith Stewart, A., Dec 1 2011, In : International Journal of Biochemistry and Molecular Biology. 2, 3, p. 287-294 8 p.Research output: Contribution to journal › Review article
43
Scopus
citations
2010
Airway eosinophilia in remission and progression of asthma: Accumulation with a fast decline of FEV1
Broekema, M., Volbeda, F., Timens, W., Dijkstra, A., Lee, N. A., Lee, J. J., Lodewijk, M. E., Postma, D. S., Hylkema, M. N. & Ten Hacken, N. H. T., Sep 1 2010, In : Respiratory Medicine. 104, 9, p. 1254-1262 9 p.Research output: Contribution to journal › Article
45
Scopus
citations
Altered eosinophil profile in mice with ST6Gal-1 deficiency: An additional role for ST6Gal-1 generated by the P1 promoter in regulating allergic inflammation
Nasirikenari, M., Chandrasekaran, E. V., Matta, K. L., Segal, B. H., Bogner, P. N., Lugade, A. A., Thanavala, Y., Lee, J. J. & Lau, J. T. Y., Mar 1 2010, In : Journal of Leukocyte Biology. 87, 3, p. 457-466 10 p.Research output: Contribution to journal › Article
25
Scopus
citations
Analysis of a cholera toxin B subunit (CTB) and human mucin 1 (MUC1) conjugate protein in a MUC1-tolerant mouse model
Pinkhasov, J., Alvarez, M. L., Pathangey, L. B., Tinder, T. L., Mason, H. S., Walmsley, A. M., Gendler, S. J. & Mukherjee, P., Dec 1 2010, In : Cancer Immunology, Immunotherapy. 59, 12, p. 1801-1811 11 p.Research output: Contribution to journal › Article
12
Scopus
citations
Dimeric arrangement of the parathyroid hormone receptor and a structural mechanism for ligand-induced dissociation
Pioszak, A. A., Harikumar, K. G., Parker, N. R., Miller, L. J. & Xu, H. E., Apr 16 2010, In : Journal of Biological Chemistry. 285, 16, p. 12435-12444 10 p.Research output: Contribution to journal › Article
49
Scopus
citations
Elucidation of the active conformation of the amino terminus of receptor-bound secretin using intramolecular disulfide bond constraints
Dong, M., Pinon, D. I., Bordner, A. J. & Miller, L. J., Oct 1 2010, In : Bioorganic and Medicinal Chemistry Letters. 20, 20, p. 6040-6044 5 p.Research output: Contribution to journal › Article
5
Scopus
citations
Eosinophils in health and disease: The LIAR hypothesis
Lee, J. J., Jacobsen, E. A., McGarry, M. P., Schleimer, R. P. & Lee, N. A., Apr 1 2010, In : Clinical and Experimental Allergy. 40, 4, p. 563-575 13 p.Research output: Contribution to journal › Comment/debate
156
Scopus
citations
Importance of lipid-exposed residues in transmembrane segment four for family B calcitonin receptor homo-dimerization
Harikumar, K. G., Ball, A. M., Sexton, P. M. & Miller, L. J., Sep 1 2010, In : Regulatory Peptides. 164, 2-3, p. 113-119 7 p.Research output: Contribution to journal › Article
22
Scopus
citations
Longevity and age-related pathology of mice deficient in pregnancy-associated plasma protein-a
Conover, C. A., Bale, L. K., Mader, J. R., Mason, M. A., Keenan, K. P. & Marler, R. J., Jun 1 2010, In : Journals of Gerontology - Series A Biological Sciences and Medical Sciences. 65 A, 6, p. 590-599 10 p.Research output: Contribution to journal › Article
58
Scopus
citations
Modulation of cell surface expression of nonactivated cholecystokinin receptors using bivalent ligand-induced internalization
Harikumar, K. G., Akgün, E., Portoghese, P. S. & Miller, L. J., Apr 8 2010, In : Journal of Medicinal Chemistry. 53, 7, p. 2836-2842 7 p.Research output: Contribution to journal › Article
14
Scopus
citations