Research Output per year
Research Output 1993 2018
- 150 - 200 out of 509 results
- Publication Year, Title (descending)
Molecular basis for binding and subtype selectivity of 1,4-benzodiazepine antagonist ligands of the cholecystokinin receptor
Cawston, E. E., Lam, P. C. H., Harikumar, K. G., Dong, M., Ball, A. M., Augustine, M. L., Akgün, E., Portoghese, P. S., Orry, A., Abagyan, R., Sexton, P. M. & Miller, L. J., May 25 2012, In : Journal of Biological Chemistry. 287, 22, p. 18618-18635 18 p.Research output: Contribution to journal › Article
MUC1 regulates PDGFA expression during pancreatic cancer progression
Sahraei, M., Roy, L. D., Curry, J. M., Teresa, T. L., Nath, S., Besmer, D., Kidiyoor, A., Dalia, R., Gendler, S. J. & Mukherjee, P., Nov 22 2012, In : Oncogene. 31, 47, p. 4935-4945 11 p.Research output: Contribution to journal › Article
Myeloid-derived suppressor cells adhere to physiologic STAT3-vs STAT5-dependent hematopoietic programming, establishing diverse tumor-mediated mechanisms of immunologic escape
Cohen, P. A., Ko, J. S., Storkus, W. J., Spencer, C. D., Bradley, J. M., Gorman, J. E., McCurry, D. B., Zorro-Manrique, S., Dominguez, A. L., Pathangey, L. B., Rayman, P. A., Rini, B. I., Gendler, S. J. & Finke, J. H., Aug 2012, In : Immunological Investigations. 41, 6-7, p. 680-710 31 p.Research output: Contribution to journal › Article
PHF20 is an effector protein of p53 double lysine methylation that stabilizes and activates p53
Cui, G., Park, S., Badeaux, A. I., Kim, D., Lee, J., Thompson, J. R., Yan, F., Kaneko, S., Yuan, Z., Botuyan, M. V., Bedford, M. T., Cheng, J. Q. & Mer, G., Sep 2012, In : Nature Structural and Molecular Biology. 19, 9, p. 916-924 9 p.Research output: Contribution to journal › Article
Placental protein 13 and decidual zones of necrosis: An immunologic diversion that may be linked to preeclampsia
Kliman, H. J., Sammar, M., Grimpel, Y. I., Lynch, S. K., Milano, K. M., Pick, E., Bejar, J., Arad, A., Lee, J. J., Meiri, H. & Gonen, R., Jan 2012, In : Reproductive Sciences. 19, 1, p. 16-30 15 p.Research output: Contribution to journal › Article
Predicting the effects of amino acid replacements in peptide hormones on their binding affinities for class B GPCRs and application to the design of secretin receptor antagonists
Te, J. A., Dong, M., Miller, L. J. & Bordner, A. J., Jul 2012, In : Journal of Computer-Aided Molecular Design. 26, 7, p. 835-845 11 p.Research output: Contribution to journal › Article
Protein tyrosine phosphatase SHP2 regulates TGF-β1 production in airway epithelia and asthmatic airway remodeling in mice
Qin, X. J., Zhang, G. S., Zhang, X., Qiu, Z. W., Wang, P. L., Li, Y. W., Li, W., Xie, Q. M., Ke, Y. H., Lee, J. J. & Shen, H. H., Dec 2012, In : Allergy: European Journal of Allergy and Clinical Immunology. 67, 12, p. 1547-1556 10 p.Research output: Contribution to journal › Article
The construction of transgenic and gene knockout/knockin mouse models of human disease
Doyle, A., McGarry, M. P., Lee, N. A. & Lee, J. J., Apr 2012, In : Transgenic Research. 21, 2, p. 327-349 23 p.Research output: Contribution to journal › Article
The development of a sensitive and specific ELISA for mouse eosinophil peroxidase: Assessment of eosinophil degranulation ex vivo and in models of human disease
Ochkur, S. I., Kim, J. D., Protheroe, C. A., Colbert, D., Moqbel, R., Lacy, P., Lee, J. J. & Lee, N. A., Jan 31 2012, In : Journal of Immunological Methods. 375, 1-2, p. 138-147 10 p.Research output: Contribution to journal › Article
The expanding role(s) of eosinophils in health and disease
Jacobsen, E., Helmers, R. A., Lee, J. J. & Lee, N. A., Nov 8 2012, In : Blood. 120, 19, p. 3882-3890 9 p.Research output: Contribution to journal › Article
Workshop report from the national institutes of health taskforce on the research needs of eosinophil-associated diseases (TREAD)
Bochner, B. S., Book, W., Busse, W. W., Butterfield, J., Furuta, G. T., Gleich, G. J., Klion, A. D., Lee, J. J., Leiferman, K. M., Minnicozzi, M., Moqbel, R., Rothenberg, M. E., Schwartz, L. B., Simon, H. U., Wechsler, M. E. & Weller, P. F., Sep 2012, In : Journal of Allergy and Clinical Immunology. 130, 3, p. 587-596 10 p.Research output: Contribution to journal › Article
CCR3 blockade attenuates eosinophilic ileitis and associated remodeling
Masterson, J. C., McNamee, E. N., Jedlicka, P., Fillon, S., Ruybal, J., Hosford, L., Rivera-Nieves, J., Lee, J. J. & Furuta, G. T., Nov 2011, In : American Journal of Pathology. 179, 5, p. 2302-2314 13 p.Research output: Contribution to journal › Article
Cereblon expression is required for the antimyeloma activity of lenalidomide and pomalidomide
Zhu, Y. X., Braggio, E. D., Shi, C. X., Bruins, L. A., Schmidt, J. E., Van Wier, S., Chang, X-B. D., Bjorklund, C. C., Fonseca, R., Bergsagel, P. L., Orlowski, R. Z. & Stewart, A. K., Nov 3 2011, In : Blood. 118, 18, p. 4771-4779 9 p.Research output: Contribution to journal › Article
Core-glycosylated mucin-like repeats from MUC1 are an apical targeting signal
Kinlough, C. L., Poland, P. A., Gendler, S. J., Mattila, P. E., Mo, D., Weisz, O. A. & Hughey, R. P., Nov 11 2011, In : Journal of Biological Chemistry. 286, 45, p. 39072-39081 10 p.Research output: Contribution to journal › Article
Efficient molecular mechanics simulations of the folding, orientation, and assembly of peptides in lipid bilayers using an implicit atomic solvation model
Bordner, A. J., Zorman, B. & Abagyan, R., Oct 2011, In : Journal of Computer-Aided Molecular Design. 25, 10, p. 895-911 17 p.Research output: Contribution to journal › Article
Eosinophilic oesophagitis in adults - A rising epidemic
Pasha, S. F., Crowell, M. D., Alexander, J. A., Harris, L. A., Achem, S. R., Farrugia, G., Lee, J. J., Thompson, D. M., Jung, K. W., Kita, H., Ravi, K., Namasivayam, V., Kim, H. J., Fleischer, D. E., Sharma, V. K. & Romero, Y., 2011, In : European Gastroenterology and Hepatology Review. 7, 1, p. 14-20 7 p.Research output: Contribution to journal › Article
Eosinophils
Lee, N. A., Dahl, M. V., Jacobsen, E. & Ochkur, S. I., Jul 27 2011, Inflammation and Allergy Drug Design. Wiley-Blackwell, p. 107-121 15 p.Research output: Chapter in Book/Report/Conference proceeding › Chapter
Eosinophils are necessary for pulmonary arterial remodeling in a mouse model of eosinophilic inflammation-induced pulmonary hypertension
Weng, M., Baron, D. M., Bloch, K. D., Luster, A. D., Lee, J. J. & Medoff, B. D., Dec 2011, In : American Journal of Physiology - Lung Cellular and Molecular Physiology. 301, 6Research output: Contribution to journal › Article
Eosinophils are required for the maintenance of plasma cells in the bone marrow
Chu, V. T., Fröhlich, A., Steinhauser, G., Scheel, T., Roch, T., Fillatreau, S., Lee, J. J., Löhning, M. & Berek, C., Feb 2011, In : Nature Immunology. 12, 2, p. 151-159 9 p.Research output: Contribution to journal › Article
Eosinophils increase neuron branching in human and murine skin and in vitro
Foster, E. L., Simpson, E. L., Fredrikson, L. J., Lee, J. J., Lee, N. A., Fryer, A. D. & Jacoby, D. B., 2011, In : PLoS One. 6, 7, e22029.Research output: Contribution to journal › Article
Eosinophils regulate dendritic cells and Th2 pulmonary immune responses following allergen provocation
Jacobsen, E., Zellner, K. R., Colbert, D., Lee, N. A. & Lee, J. J., Dec 1 2011, In : Journal of Immunology. 187, 11, p. 6059-6068 10 p.Research output: Contribution to journal › Article
Fluorescence polarization screening for allosteric small molecule ligands of the cholecystokinin receptor
Harikumar, K. G., Cawston, E. E. & Miller, L. J., Aug 1 2011, In : Assay and Drug Development Technologies. 9, 4, p. 394-402 9 p.Research output: Contribution to journal › Article
Glutamine residues in Q-loops of multidrug resistance protein MRP1 contribute to ATP binding via interaction with metal cofactor
Yang, R., Hou, Y. X., Campbell, C. A., Palaniyandi, K., Zhao, Q., Bordner, A. J. & Chang, X-B. D., Jul 2011, In : Biochimica et Biophysica Acta - Biomembranes. 1808, 7, p. 1790-1796 7 p.Research output: Contribution to journal › Article
Immunodetection of occult eosinophils in lung tissue biopsies may help predict survival in acute lung injury
Willetts, L., Parker, K., Wesselius, L. J., Protheroe, C. A., Jaben, E., Graziano, P., Moqbel, R., Leslie, K. O., Lee, N. A. & Lee, J. J., Aug 26 2011, In : Respiratory Research. 12, 116.Research output: Contribution to journal › Article
Importance and regulation of the colonic mucus barrier in a mouse model of colitis
Petersson, J., Schreiber, O., Hansson, G. C., Gendler, S. J., Velcich, A., Lundberg, J. O., Roos, S., Holm, L. & Phillipson, M., Feb 2011, In : American Journal of Physiology - Gastrointestinal and Liver Physiology. 300, 2Research output: Contribution to journal › Article
Importance of each residue within secretin for receptor binding and biological activity
Dong, M., Le, A., Te, J. A., Pinon, D. I., Bordner, A. J. & Miller, L. J., Apr 12 2011, In : Biochemistry. 50, 14, p. 2983-2993 11 p.Research output: Contribution to journal › Article
Infection of H69AR cells with retroviral particles harboring interfering RNAi significantly reduced the multidrug resistance of these small cell lung cancer cells
Palaniyandi, K., Zhao, Q. & Chang, X-B. D., 2011, In : International Journal of Biochemistry and Molecular Biology. 2, 2, p. 155-167 13 p.Research output: Contribution to journal › Article
Lactam constraints provide insights into the receptor-bound conformation of secretin and stabilize a receptor antagonist
Dong, M., Te, J. A., Xu, X., Wang, J., Pinon, D. I., Storjohann, L., Bordner, A. J. & Miller, L. J., Sep 27 2011, In : Biochemistry. 50, 38, p. 8181-8192 12 p.Research output: Contribution to journal › Article
Local proliferation and mobilization of CCR3+ CD34+ eosinophil-lineage-committed cells in the lung
Rådinger, M., Bossios, A., Sjöstrand, M., Lu, Y., Malmhäll, C., Dahlborn, A. K., Lee, J. J. & Lötvall, J., Jan 2011, In : Immunology. 132, 1, p. 144-154 11 p.Research output: Contribution to journal › Article
Major basic protein from eosinophils and myeloperoxidase from neutrophils are required for protective immunity to Strongyloides stercoralis in mice
O'Connell, A. E., Hess, J. A., Santiago, G. A., Nolan, T. J., Lok, J. B., Lee, J. J. & Abraham, D., Jul 2011, In : Infection and Immunity. 79, 7, p. 2770-2778 9 p.Research output: Contribution to journal › Article
MUC1 enhances invasiveness of pancreatic cancer cells by inducing epithelial to mesenchymal transition
Roy, L. D., Sahraei, M., Subramani, D. B., Besmer, D., Nath, S., Tinder, T. L., Bajaj, E., Shanmugam, K., Lee, Y. Y., Hwang, S. I. L., Gendler, S. J. & Mukherjee, P., Mar 24 2011, In : Oncogene. 30, 12, p. 1449-1459 11 p.Research output: Contribution to journal › Article
Pancreatic ductal adenocarcinoma mice lacking mucin 1 have a profound defect in tumor growth and metastasis
Besmer, D. M., Curry, J. M., Roy, L. D., Tinder, T. L., Sahraei, M., Schettini, J., Hwang, S. I., Lee, Y. Y., Gendler, S. J. & Mukherjee, P., Jul 1 2011, In : Cancer Research. 71, 13, p. 4432-4442 11 p.Research output: Contribution to journal › Article
Recombinant plant-expressed tumour-associated MUC1 peptide is immunogenic and capable of breaking tolerance in MUC1.Tg mice
Pinkhasov, J., Alvarez, M. L., Rigano, M. M., Piensook, K., Larios, D., Pabst, M., Grass, J., Mukherjee, P., Gendler, S. J., Walmsley, A. M. & Mason, H. S., Dec 2011, In : Plant Biotechnology Journal. 9, 9, p. 991-1001 11 p.Research output: Contribution to journal › Article
The identification of eosinophilic gastroenteritis in prednisone-dependent eosinophilic bronchitis and asthma
Nair, P., Ochkur, S. I., Protheroe, C., Simms, E., Lee, N. A. & Lee, J. J., Mar 1 2011, In : Allergy, Asthma and Clinical Immunology. 7, 1, 4.Research output: Contribution to journal › Article
The Pyk2 FERM regulates Pyk2 complex formation and phosphorylation
Riggs, D., Yang, Z., Kloss, J. & Loftus, J. C., Jan 2011, In : Cellular Signalling. 23, 1, p. 288-296 9 p.Research output: Contribution to journal › Article
Update on clinical and immunological features of eosinophilic gastrointestinal diseases
Masterson, J. C., Furuta, G. T. & Lee, J. J., Oct 2011, In : Current Opinion in Gastroenterology. 27, 6, p. 515-522 8 p.Research output: Contribution to journal › Article
What is the functional role of the thalidomide binding protein cereblon?
Chang, X-B. D. & Stewart, A. K., 2011, In : International Journal of Biochemistry and Molecular Biology. 2, 3, p. 287-294 8 p.Research output: Contribution to journal › Article
Airway eosinophilia in remission and progression of asthma: Accumulation with a fast decline of FEV1
Broekema, M., Volbeda, F., Timens, W., Dijkstra, A., Lee, N. A., Lee, J. J., Lodewijk, M. E., Postma, D. S., Hylkema, M. N. & Ten Hacken, N. H. T., Sep 2010, In : Respiratory Medicine. 104, 9, p. 1254-1262 9 p.Research output: Contribution to journal › Article
Altered eosinophil profile in mice with ST6Gal-1 deficiency: An additional role for ST6Gal-1 generated by the P1 promoter in regulating allergic inflammation
Nasirikenari, M., Chandrasekaran, E. V., Matta, K. L., Segal, B. H., Bogner, P. N., Lugade, A. A., Thanavala, Y., Lee, J. J. & Lau, J. T. Y., Mar 2010, In : Journal of Leukocyte Biology. 87, 3, p. 457-466 10 p.Research output: Contribution to journal › Article
Analysis of a cholera toxin B subunit (CTB) and human mucin 1 (MUC1) conjugate protein in a MUC1-tolerant mouse model
Pinkhasov, J., Alvarez, M. L., Pathangey, L. B., Tinder, T. L., Mason, H. S., Walmsley, A. M., Gendler, S. J. & Mukherjee, P., Dec 2010, In : Cancer Immunology, Immunotherapy. 59, 12, p. 1801-1811 11 p.Research output: Contribution to journal › Article
Dimeric arrangement of the parathyroid hormone receptor and a structural mechanism for ligand-induced dissociation
Pioszak, A. A., Harikumar, K. G., Parker, N. R., Miller, L. J. & Xu, H. E., Apr 16 2010, In : Journal of Biological Chemistry. 285, 16, p. 12435-12444 10 p.Research output: Contribution to journal › Article
Elucidation of the active conformation of the amino terminus of receptor-bound secretin using intramolecular disulfide bond constraints
Dong, M., Pinon, D. I., Bordner, A. J. & Miller, L. J., Oct 2010, In : Bioorganic and Medicinal Chemistry Letters. 20, 20, p. 6040-6044 5 p.Research output: Contribution to journal › Article
Eosinophils in health and disease: The LIAR hypothesis
Lee, J. J., Jacobsen, E., McGarry, M. P., Schleimer, R. P. & Lee, N. A., Apr 2010, In : Clinical and Experimental Allergy. 40, 4, p. 563-575 13 p.Research output: Contribution to journal › Article
Importance of lipid-exposed residues in transmembrane segment four for family B calcitonin receptor homo-dimerization
Harikumar, K. G., Ball, A. M., Sexton, P. M. & Miller, L. J., Sep 2010, In : Regulatory Peptides. 164, 2-3, p. 113-119 7 p.Research output: Contribution to journal › Article
Longevity and age-related pathology of mice deficient in pregnancy-associated plasma protein-a
Conover, C. A., Bale, L. K., Mader, J. R., Mason, M. A., Keenan, K. P. & Marler, R. J., Jun 2010, In : Journals of Gerontology - Series A Biological Sciences and Medical Sciences. 65 A, 6, p. 590-599 10 p.Research output: Contribution to journal › Article
Modulation of cell surface expression of nonactivated cholecystokinin receptors using bivalent ligand-induced internalization
Harikumar, K. G., Akgün, E., Portoghese, P. S. & Miller, L. J., Apr 8 2010, In : Journal of Medicinal Chemistry. 53, 7, p. 2836-2842 7 p.Research output: Contribution to journal › Article
Molecular mechanism of ATP-dependent solute transport by multidrug resistance-associated protein 1.
Chang, X-B. D., 2010, In : Methods in molecular biology (Clifton, N.J.). 596, p. 223-249 27 p.Research output: Contribution to journal › Article
MultiRTA: A simple yet reliable method for predicting peptide binding affinities for multiple class II MHC allotypes
Bordner, A. J. & Mittelmann, H. D., Sep 24 2010, In : BMC Bioinformatics. 11, 482.Research output: Contribution to journal › Article
Murine lung eosinophil activation and chemokine production in allergic airway inflammation
Rose, C. E., Lannigan, J. A., Kim, P., Lee, J. J., Fu, S. M. & Sung, S. S. J., 2010, In : Cellular and Molecular Immunology. 7, 5, p. 361-374 14 p.Research output: Contribution to journal › Article
Novel model of TH2-polarized chronic ileitis: The SAMPl mouse
McNamee, E. N., Wermers, J. D., Masterson, J. C., Collins, C. B., Matthew, D. P., Lebsack, B. A., Fillon, S., Robinson, Z. D., Grenawalt, J., Lee, J. J., Jedlicka, P., Furuta, G. T. & Rivera-Nieves, J., 2010, In : Inflammatory Bowel Diseases. 16, 5, p. 743-752 10 p.Research output: Contribution to journal › Article