Biochemistry and Molecular Biology

Research Output 1993 2018

2016
4 Citations (Scopus)

Structure and function of Cross-class complexes of G Protein-Coupled secretin and angiotensin 1a receptors

Harikumar, K. G., Augustine, M. L., Lee, L. T. O., Chow, B. K. C. & Miller, L. J., Aug 12 2016, In : Journal of Biological Chemistry. 291, 33, p. 17332-17344 13 p.

Research output: Contribution to journalArticle

Angiotensin Receptors
Secretin
Angiotensins
GTP-Binding Proteins
Calcium
3 Citations (Scopus)

Targeting granulocyte-macrophage colony-stimulating factor in epithelial and vascular remodeling in experimental eosinophilic esophagitis

Mcnamee, E. N., Biette, K. A., Hammer, J., Harris, R., Miyazawa, H., Lee, J. J., Furuta, G. T. & Masterson, J. C., 2016, (Accepted/In press) In : Allergy: European Journal of Allergy and Clinical Immunology.

Research output: Contribution to journalArticle

Eosinophilic Esophagitis
Granulocyte-Macrophage Colony-Stimulating Factor
Eosinophils
Eosinophilia
Granulocyte-Macrophage Colony-Stimulating Factor Receptors
3 Citations (Scopus)

The potential for repositioning antithyroid agents as antiasthma drugs

Suzuki, S., Ogawa, M., Ohta, S., Arima, K., Nunomura, S., Nanri, Y., Mitamura, Y., Yoshihara, T., Nakamura, Y., Yamauchi, K., Chibana, K., Ishii, Y., Lee, J. J., Aratani, Y., Kakuta, S., Kubo, S., Iwakura, Y., Yoshida, H. & Izuhara, K., 2016, (Accepted/In press) In : Journal of Allergy and Clinical Immunology.

Research output: Contribution to journalArticle

Antithyroid Agents
Pharmaceutical Preparations
12 Citations (Scopus)

Tumor eosinophil infiltration and improved survival of colorectal cancer patients: Iowa Women’s Health Study

Prizment, A. E., Vierkant, R. A., Smyrk, T. C., Tillmans, L. S., Lee, J. J., Sriramarao, P., Nelson, H. H., Lynch, C. F., Thibodeau, S. N., Church, T. R., Cerhan, J. R., Anderson, K. E. & Limburg, P. J., Feb 26 2016, (Accepted/In press) In : Modern Pathology.

Research output: Contribution to journalArticle

Women's Health
Eosinophils
Colorectal Neoplasms
Survival
Neoplasms
2015

Development of an endometrial ablation model in New Zealand White rabbits

AlHilli, M. M., Brost, B. C., Marler, R. J., Mariani, A., Hopkins, M. R. & Famuyide, A. O., Aug 1 2015, In : The Journal of reproductive medicine. 60, 4, p. 315-323 9 p.

Research output: Contribution to journalArticle

Endometrial Ablation Techniques
Rabbits
Endometrial Neoplasms
Incineration
Myometrium
24 Citations (Scopus)

Differential activation of airway eosinophils induces IL-13-mediated allergic Th2 pulmonary responses in mice

Jacobsen, E., Doyle, A. D., Colbert, D. C., Zellner, K. R., Protheroe, C. A., Lesuer, W. E., Lee, N. A. & Lee, J. J., Sep 1 2015, In : Allergy: European Journal of Allergy and Clinical Immunology. 70, 9, p. 1148-1159 12 p.

Research output: Contribution to journalArticle

Interleukin-13
Eosinophils
Lung
Interleukin-4
Granulocyte-Macrophage Colony-Stimulating Factor
11 Citations (Scopus)

Dual proinflammatory and antiviral properties of pulmonary eosinophils in respiratory syncytial virus vaccine-enhanced disease

Su, Y. C., Townsend, D., Herrero, L. J., Zaid, A., Rolph, M. S., Gahan, M. E., Nelson, M. A., Rudd, P. A., Matthaei, K. I., Foster, P. S., Dent, L., Tripp, R. A., Lee, J., Simson, L. & Mahalingam, S., 2015, In : Journal of Virology. 89, 3, p. 1564-1578 15 p.

Research output: Contribution to journalArticle

Respiratory Syncytial Virus Vaccines
antiviral properties
Respiratory Syncytial Viruses
eosinophils
Eosinophils
3 Citations (Scopus)

Endoscopic band ligation for closure of GI perforations in a porcine animal model (with video)

Law, R., Deters, J. L., Miller, C. A., Marler, R. J. & Baron, T. H., 2015, In : Gastrointestinal Endoscopy. 80, 4, p. 717-722 6 p.

Research output: Contribution to journalArticle

Esophageal Perforation
Ligation
Swine
Animal Models
Peritonitis
9 Citations (Scopus)

Eosinophil-associated ribonuclease 11 is a macrophage chemoattractant

Yamada, K. J., Barker, T., Dyer, K. D., Rice, T. A., Percopo, C. M., Garcia-Crespo, K. E., Cho, S., Lee, J. J., Druey, K. M. & Rosenberg, H. F., Apr 3 2015, In : Journal of Biological Chemistry. 290, 14, p. 8863-8875 13 p.

Research output: Contribution to journalArticle

Eosinophil Cationic Protein
Macrophages
Chemotactic Factors
Ribonucleases
Pancreatic Ribonuclease
13 Citations (Scopus)

Eosinophil-dependent skin innervation and itching following contact toxicant exposure in mice

Lee, J. J., Protheroe, C. A., Luo, H., Ochkur, S. I., Scott, G. D., Zellner, K. R., Raish, R. J., Dahl, M. V., Vega, M. L., Conley, O., Condjella, R. M., Kloeber, J. A., Neely, J. L., Patel, Y. S., Maizer, P., Mazzolini, A., Fryer, A. D., Jacoby, N. W., Jacoby, D. B. & Lee, N. A., Feb 1 2015, In : Journal of Allergy and Clinical Immunology. 135, 2, p. 477-487 11 p.

Research output: Contribution to journalArticle

Pruritus
Eosinophils
Skin
Substance P
Dinitrofluorobenzene
47 Citations (Scopus)

Eosinophil-mediated signalling attenuates inflammatory responses in experimental colitis

Masterson, J. C., McNamee, E. N., Fillon, S. A., Hosford, L., Harris, R., Fernando, S. D., Jedlicka, P., Iwamoto, R., Jacobsen, E., Protheroe, C., Eltzschig, H. K., Colgan, S. P., Arita, M., Lee, J. J. & Furuta, G. T., Aug 1 2015, In : Gut. 64, 8, p. 1236-1247 12 p.

Research output: Contribution to journalArticle

Colitis
Eosinophils
Neutrophils
Colon
Chemokine CXCL1
25 Citations (Scopus)

Eosinophils and IL-33 Perpetuate Chronic Inflammation and Fibrosis in a Pediatric Population with Stricturing Crohn's Ileitis

Masterson, J. C., Capocelli, K. E., Hosford, L., Biette, K., McNamee, E. N., De Zoeten, E. F., Harris, R., Fernando, S. D., Jedlicka, P., Protheroe, C., Lee, J. J. & Furuta, G. T., Jul 20 2015, In : Inflammatory Bowel Diseases. 21, 10, p. 2429-2440 12 p.

Research output: Contribution to journalArticle

Ileitis
Eosinophils
Fibrosis
Pediatrics
Inflammation
20 Citations (Scopus)

Eosinophils and IL-4 Support Nematode Growth Coincident with an Innate Response to Tissue Injury

Huang, L., Beiting, D. P., Gebreselassie, N. G., Gagliardo, L. F., Ruyechan, M. C., Lee, N. A., Lee, J. J. & Appleton, J. A., 2015, In : PLoS Pathogens. 11, 12, e1005347.

Research output: Contribution to journalArticle

Eosinophils
Interleukin-4
Wounds and Injuries
Growth
Larva
13 Citations (Scopus)

Eosinophils contribute to the resolution of lung-allergic responses following repeated allergen challenge

Takeda, K., Shiraishi, Y., Ashino, S., Han, J., Jia, Y., Wang, M., Lee, N. A., Lee, J. J. & Gelfand, E. W., Feb 1 2015, In : Journal of Allergy and Clinical Immunology. 135, 2, p. 451-460 10 p.

Research output: Contribution to journalArticle

Eosinophils
Allergens
Interleukin-10
Lung
Ovalbumin
28 Citations (Scopus)

Eosinophils mediate protective immunity against secondary nematode infection

Huang, L., Gebreselassie, N. G., Gagliardo, L. F., Ruyechan, M. C., Luber, K. L., Lee, N. A., Lee, J. J. & Appleton, J. A., Jan 1 2015, In : Journal of Immunology. 194, 1, p. 283-290 8 p.

Research output: Contribution to journalArticle

Nematode Infections
Coinfection
Eosinophils
Immunity
Larva
13 Citations (Scopus)

Exogenous interleukin-17a inhibits eosinophil differentiation and alleviates allergic airway inflammation

Tian, B. P., Hua, W., Xia, L. X., Jin, Y., Lan, F., Lee, J. J., Lee, N. A., Li, W., Ying, S. M., Chen, Z. H. & Shen, H. H., Apr 1 2015, In : American Journal of Respiratory Cell and Molecular Biology. 52, 4, p. 459-470 12 p.

Research output: Contribution to journalArticle

Interleukin-17
Eosinophils
Inflammation
Interleukin-5
GATA2 Transcription Factor
7 Citations (Scopus)
Ursodeoxycholic Acid
Binding Sites
Cholesterol
Cholecystokinin Receptors
Bile Acids and Salts
22 Citations (Scopus)

Linear synthesis and immunological properties of a fully synthetic vaccine candidate containing a sialylated MUC1 glycopeptide

Thompson, P., Lakshminarayanan, V., Supekar, N. T., Bradley, J. M., Cohen, P. A., Wolfert, M. A., Gendler, S. J. & Boons, G. J., May 28 2015, In : Chemical Communications. 51, 50, p. 10214-10217 4 p.

Research output: Contribution to journalArticle

Synthetic Vaccines
Vaccines
Glycopeptides
Cancer Vaccines
T-cells
9 Citations (Scopus)

Low-Dose Gamma Irradiation of Decellularized Heart Valves Results in Tissue Injury In Vitro and In Vivo

Helder, M. R. K., Hennessy, R. S., Spoon, D. B., Tefft, B. J., Witt, T. A., Marler, R. J., Pislaru, S. V., Simari, R. D., Stulak, J. M. & Lerman, A., 2015, (Accepted/In press) In : Annals of Thoracic Surgery.

Research output: Contribution to journalArticle

Heart Valves
Wounds and Injuries
Hematoxylin
Eosine Yellowish-(YS)
Staining and Labeling
17 Citations (Scopus)

Muc1 is protective during kidney ischemia - Reperfusion injury

Pastor-Soler, N. M., Sutton, T. A., Mang, H. E., Kinlough, C. L., Gendler, S. J., Madsen, C. S., Bastacky, S. I., Ho, J., Al-Bataineh, M. M., Hallows, K. R., Singh, S., Monga, S. P., Kobayashi, H., Haase, V. H. & Hughey, R. P., Jun 15 2015, In : American Journal of Physiology - Renal Physiology. 308, 12, p. F1452-F1462

Research output: Contribution to journalArticle

Mucin-1
Reperfusion Injury
Kidney
Hypoxia-Inducible Factor 1
Transcription Factors
41 Citations (Scopus)

Multi-parametric MRI and texture analysis to visualize spatial histologic heterogeneity and tumor extent in glioblastoma

Hu, L. S., Ning, S., Eschbacher, J. M., Gaw, N., Dueck, A., Smith, K. A., Nakaji, P., Plasencia, J., Ranjbar, S., Price, S. J., Tran, N., Loftus, J. C., Jenkins, R. B., O'Neill, B. P., Elmquist, W., Baxter, L. C., Gao, F., Frakes, D., Karis, J. P., Zwart, C. & 5 others, Swanson, K., Sarkaria, J. N., Wu, T., Mitchell, J. R. & Li, J., Nov 1 2015, In : PLoS One. 10, 11, e0141506.

Research output: Contribution to journalArticle

Glioblastoma
Magnetic resonance imaging
Tumors
Textures
texture
19 Citations (Scopus)

Nasal and pharyngeal eosinophil peroxidase levels in adults with poorly controlled asthma correlate with sputum eosinophilia

Rank, M. A., Ochkur, S. I., Lewis, J. C., Teaford, H. G., Wesselius, L. J., Helmers, R. A., Lee, N. A., Nair, P. & Lee, J. J., 2015, (Accepted/In press) In : Allergy: European Journal of Allergy and Clinical Immunology.

Research output: Contribution to journalArticle

Eosinophil Peroxidase
Eosinophilia
Sputum
Nose
Asthma
41 Citations (Scopus)

Pediatric Eosinophilic Esophagitis Symptom Scores (PEESS v2.0) identify histologic and molecular correlates of the key clinical features of disease

Martin, L. J., Franciosi, J. P., Collins, M. H., Abonia, J. P., Lee, J. J., Hommel, K. A., Varni, J. W., Grotjan, J. T., Eby, M., He, H., Marsolo, K., Putnam, P. E., Garza, J. M., Kaul, A., Wen, T. & Rothenberg, M. E., Jun 1 2015, In : Journal of Allergy and Clinical Immunology. 135, 6, p. 1519-1528e8

Research output: Contribution to journalArticle

Eosinophilic Esophagitis
Pediatrics
Deglutition Disorders
Gastroesophageal Reflux
Nausea
4 Citations (Scopus)

Pregnancy-associated plasma protein-A deficiency improves survival of mice on a high fat diet

Conover, C. A., Bale, L. K. & Marler, R. J., Oct 1 2015, In : Experimental Gerontology. 70, p. 131-134 4 p., 9677.

Research output: Contribution to journalArticle

Pregnancy-Associated Plasma Protein-A
Protein Deficiency
High Fat Diet
Nutrition
Fats
30 Citations (Scopus)

Recellularization of decellularized lung scaffolds is enhanced by dynamic suspension culture

Crabbé, A., Liu, Y., Sarker, S. F., Bonenfant, N. R., Barrila, J., Borg, Z. D., Lee, J. J., Weiss, D. J. & Nickerson, C. A., May 11 2015, In : PLoS One. 10, 5, e0126846.

Research output: Contribution to journalArticle

Bioreactors
Scaffolds
Suspensions
lungs
Lung
2014
42 Citations (Scopus)

Activated mouse eosinophils protect against lethal respiratory virus infection

Percopo, C. M., Dyer, K. D., Ochkur, S. I., Luo, J. L., Fischer, E. R., Lee, J. J., Lee, N. A., Domachowske, J. B. & Rosenberg, H. F., Jan 30 2014, In : Blood. 123, 5, p. 743-752 10 p.

Research output: Contribution to journalArticle

Virus Diseases
Murine pneumonia virus
Viruses
Eosinophils
Respiratory Tract Infections
19 Citations (Scopus)

Adenine nucleotide translocase is acetylated in vivo in human muscle: Modeling predicts a decreased ADP affinity and altered control of oxidative phosphorylation

Mielke, C., Lefort, N., McLean, C. G., Cordova, J. M., Langlais, P. R., Bordner, A. J., Te, J. A., Ozkan, S. B., Willis, W. T. & Mandarino, L. J., Jun 17 2014, In : Biochemistry. 53, 23, p. 3817-3829 13 p.

Research output: Contribution to journalArticle

ATP Translocases Mitochondrial ADP
Acetylation
Oxidative Phosphorylation
Adenosine Diphosphate
Muscle
7 Citations (Scopus)

A new formulation of protein evolutionary models that account for structural constraints

Bordner, A. J. & Mittelmann, H. D., 2014, In : Molecular Biology and Evolution. 31, 3, p. 736-749 14 p.

Research output: Contribution to journalArticle

Structural Models
protein
Amino Acids
Proteins
proteins
11 Citations (Scopus)

A type 1 cholecystokinin receptor mutant that mimics the dysfunction observed for wild type receptor in a high cholesterol environment

Desai, A. J., Harikumar, K. G. & Miller, L. J., Jun 27 2014, In : Journal of Biological Chemistry. 289, 26, p. 18314-18326 13 p.

Research output: Contribution to journalArticle

Cholecystokinin A Receptor
Cholecystokinin Receptors
Cholecystokinin
Cholesterol
Ligands
50 Citations (Scopus)

Changing roles of eosinophils in health and disease

Furuta, G. T., Atkins, F. D., Lee, N. A. & Lee, J. J., 2014, In : Annals of Allergy, Asthma and Immunology. 113, 1, p. 3-8 6 p.

Research output: Contribution to journalArticle

Eosinophils
Health
Information Storage and Retrieval
Parasites
Homeostasis
96 Citations (Scopus)

Development and validation of a symptom-based activity index for adults with eosinophilic esophagitis

Schoepfer, A. M., Straumann, A., Panczak, R., Coslovsky, M., Kuehni, C. E., Maurer, E., Haas, N. A., Romero, Y., Hirano, I., Alexander, J. A., Gonsalves, N., Furuta, G. T., Dellon, E. S., Leung, J., Collins, M. H., Bussmann, C., Netzer, P., Gupta, S. K., Aceves, S. S., Chehade, M. & 46 others, Moawad, F. J., Enders, F. T., Yost, K. J., Taft, T. H., Kern, E., Zwahlen, M., Safroneeva, E., Achem, S. R., Arora, A. S., Alpan, O., Armstrong, D., Attwood, S. E., Butterfield, J. H., Crowell, M. D., De Petris, G., DeVault, K. R., Drouin, E., Enav, B., Fleischer, D. E., Foxx-Orenstein, A., Francis, D. L., Guyatt, G. H., Harris, L. A., Kagalwalla, A. F., Katzka, D. A., Kita, H., Krishna, M., Lee, J. J., Lewis, J. C., Lim, K., Locke, G. R., Murray, J. A., Nguyen, C. C., Orbelo, D. M., Pasha, S. F., Ramirez, F. C., Sheikh, J., Smyrk, T. C., Spergel, J. M., Umar, S. B., Weiler, C. R., Wo, J. M., Woosley, J. T., Wu, T. T., Yan, P. & Yang, G. Y., Dec 1 2014, In : Gastroenterology. 147, 6, p. 1255-1266.e21

Research output: Contribution to journalArticle

Eosinophilic Esophagitis
Deglutition Disorders
Validation Studies
Deglutition
Focus Groups
6 Citations (Scopus)

Differential expression of microRNAs as predictors of glioblastoma phenotypes

Bradley, B. S., Loftus, J. C., Mielke, C. J. & Dinu, V., Jan 18 2014, In : BMC Bioinformatics. 15, 1, 21.

Research output: Contribution to journalArticle

MicroRNA
Differential Expression
Glioblastoma
MicroRNAs
Phenotype
28 Citations (Scopus)

Eosinophil activities modulate the immune/inflammatory character of allergic respiratory responses in mice

Jacobsen, E., LeSuer, W. E., Willetts, L., Zellner, K. R., Mazzolini, K., Antonios, N., Beck, B., Protheroe, C., Ochkur, S. I., Colbert, D., Lacy, P., Moqbel, R., Appleton, J., Lee, N. A. & Lee, J. J., Mar 2014, In : Allergy: European Journal of Allergy and Clinical Immunology. 69, 3, p. 315-327 13 p.

Research output: Contribution to journalArticle

Eosinophils
Phenotype
Allergens
Respiratory Hypersensitivity
Gene Knock-In Techniques
39 Citations (Scopus)

Eosinophil-derived IL-10 supports chronic nematode infection

Huang, L., Gebreselassie, N. G., Gagliardo, L. F., Ruyechan, M. C., Lee, N. A., Lee, J. J. & Appleton, J. A., Oct 15 2014, In : Journal of Immunology. 193, 8, p. 4178-4187 10 p.

Research output: Contribution to journalArticle

Nematode Infections
Eosinophils
Interleukin-10
Infection
Helminths
35 Citations (Scopus)

Eosinophils Are Important for Protection, Immunoregulation and Pathology during Infection with Nematode Microfilariae

Cadman, E. T., Thysse, K. A., Bearder, S., Cheung, A. Y. N., Johnston, A. C., Lee, J. J. & Lawrence, R. A., 2014, In : PLoS Pathogens. 10, 3, e1003988.

Research output: Contribution to journalArticle

Nematode Infections
Microfilariae
Eosinophils
Pathology
Eosinophil Peroxidase
5 Citations (Scopus)

Eosinophil shape change and secretion

Willetts, L., Ochkur, S. I., Jacobsen, E., Lee, J. J. & Lacy, P., 2014, Methods in Molecular Biology. Humana Press Inc., Vol. 1178. p. 111-128 18 p. (Methods in Molecular Biology; vol. 1178).

Research output: Chapter in Book/Report/Conference proceedingChapter

Eosinophils
Eosinophil Peroxidase
Chemokine CCL11
Immunosorbent Techniques
Platelet Activating Factor
24 Citations (Scopus)

Eosinophils regulate peripheral B cell numbers in both mice and humans

Wong, T. W., Doyle, A. D., Lee, J. J. & Jelinek, D. F., Apr 15 2014, In : Journal of Immunology. 192, 8, p. 3548-3558 11 p.

Research output: Contribution to journalArticle

Eosinophils
B-Lymphocytes
Cell Count
Cell Proliferation
Cell Survival
30 Citations (Scopus)

Fumarylacetoacetate hydrolase deficient pigs are a novel large animal model of metabolic liver disease

Hickey, R., Mao, S. A., Glorioso, J., Lillegard, J. B., Fisher, J. E., Amiot, B., Rinaldo, P., Harding, C. O., Marler, R. J., Finegold, M. J., Grompe, M. & Nyberg, S., 2014, In : Stem Cell Research. 13, 1, p. 144-153 10 p.

Research output: Contribution to journalArticle

Metabolic Diseases
Liver Diseases
Swine
Animal Models
Liver
89 Citations (Scopus)

Identification of cereblon-binding proteins and relationship with response and survival after IMiDs in multiple myeloma

Zhu, Y. X., Braggio, E. D., Shi, C. X., Kortuem, K. M., Bruins, L. A., Schmidt, J. E., Chang, X-B. D., Langlais, P. R., Luo, M., Jedlowski, P., LaPlant, B., Laumann, K., Fonseca, R., Bergsagel, P. L., Mikhael, J. R., Lacy, M., Champion, M. D. & Stewart, A. K., Jul 24 2014, In : Blood. 124, 4, p. 536-545 10 p.

Research output: Contribution to journalArticle

Multiple Myeloma
Carrier Proteins
Survival
Cells
Ports and harbors
33 Citations (Scopus)

Immune and anticancer responses elicited by fully synthetic aberrantly glycosylated MUC1 tripartite vaccines modified by a TLR2 or TLR9 agonist

Abdel-Aal, A. B. M., Lakshminarayanan, V., Thompson, P., Supekar, N., Bradley, J. M., Wolfert, M. A., Cohen, P. A., Gendler, S. J. & Boons, G. J., Jul 7 2014, In : ChemBioChem. 15, 10, p. 1508-1513 6 p.

Research output: Contribution to journalArticle

T-cells
Tumors
Vaccines
Glycopeptides
Cytotoxic T-Lymphocytes
11 Citations (Scopus)

Inactivation of the transcription factor GLI1 accelerates pancreatic cancer progression

Mills, L. D., Zhang, L., Marler, R. J., Svingen, P., Fernandez-Barrena, M. G., Dave, M., Bamlet, W., Mc Williams, R. R., Petersen, G. M., Faubion, W. A. & Fernandez-Zapico, M. E., Jun 6 2014, In : Journal of Biological Chemistry. 289, 23, p. 16516-16525 10 p.

Research output: Contribution to journalArticle

Pancreatic Neoplasms
Tumors
Transcription Factors
Neoplasms
Knockout Mice
19 Citations (Scopus)

Inhibition of adaptive immunity by IL9 can be disrupted to achieve rapid t-cell sensitization and rejection of progressive tumor challenges

Hoelzinger, D. B., Dominguez, A. L., Cohen, P. A. & Gendler, S. J., Dec 1 2014, In : Cancer Research. 74, 23, p. 6845-6855 11 p.

Research output: Contribution to journalArticle

Interleukin-9
Adaptive Immunity
Neoplasms
Immunologic Memory
T-Lymphocytes
24 Citations (Scopus)

Local hypersensitivity reaction in transgenic mice with squamous epithelial IL-5 overexpression provides a novel model of eosinophilic oesophagitis

Masterson, J. C., McNamee, E. N., Hosford, L., Capocelli, K. E., Ruybal, J., Fillon, S. A., Doyle, A. D., Eltzschig, H. K., Rustgi, A. K., Protheroe, C. A., Lee, N. A., Lee, J. J. & Furuta, G. T., Jan 2014, In : Gut. 63, 1, p. 43-53 11 p.

Research output: Contribution to journalArticle

Eosinophilic Esophagitis
Interleukin-5
Transgenic Mice
Eosinophilia
Hypersensitivity
36 Citations (Scopus)

Mechanism of immunomodulatory drugs' action in the treatment of multiple myeloma

Chang, X-B. D., Zhu, Y., Shi, C. & Stewart, A. K., Mar 2014, In : Acta Biochimica et Biophysica Sinica. 46, 3, p. 240-253 14 p.

Research output: Contribution to journalArticle

Multiple Myeloma
Cells
Cell Migration Inhibition
Thalidomide
Oncology
28 Citations (Scopus)

Predicting response to bacillus Calmette-Guérin (BCG) in patients with carcinoma in situ of the bladder

Nunez-Nateras, R., Castle, E. P., Protheroe, C. A., Stanton, M. L., Ocal, T. I., Ferrigni, E. N., Ochkur, S. I., Jacobsen, E., Hou, Y. X., Andrews, P. E., Colby, T. V., Lee, N. A. & Lee, J. J., Jan 2014, In : Urologic Oncology: Seminars and Original Investigations. 32, 1

Research output: Contribution to journalArticle

Carcinoma in Situ
Bacillus
Urinary Bladder
Tumor Microenvironment
Lymphocytes
40 Citations (Scopus)

Re-defining the unique roles for eosinophils in allergic respiratory inflammation

Jacobsen, E., Lee, N. A. & Lee, J. J., 2014, In : Clinical and Experimental Allergy. 44, 9, p. 1119-1136 18 p.

Research output: Contribution to journalArticle

Eosinophils
Inflammation
Lung
Allergens
Pneumonia
7 Citations (Scopus)

Surfactant protein D attenuates sub-epithelial fibrosis in allergic airways disease through TGF-β

Ogawa, H., Ledford, J. G., Mukherjee, S., Aono, Y., Nishioka, Y., Lee, J. J., Izumi, K. & Hollingsworth, J. W., Nov 29 2014, In : Respiratory Research. 15, 1, 143.

Research output: Contribution to journalArticle

Pulmonary Surfactant-Associated Protein D
Fibrosis
Dermatophagoides pteronyssinus
Eosinophils
Interleukin-13
3 Citations (Scopus)

Sustained inflammation and differential expression of interferons type I and III in PVM-infected interferon-gamma (IFNγ) gene-deleted mice

Glineur, S. F., Bowen, A. B., Percopo, C. M., Garcia-Crespo, K. E., Dyer, K. D., Ochkur, S. I., Lee, N. A., Lee, J. J., Domachowske, J. B. & Rosenberg, H. F., 2014, In : Virology. 468-470, p. 140-149 10 p.

Research output: Contribution to journalArticle

Interferon Type I
Interferon-gamma
Inflammation
Genes
Pneumovirus Infections
31 Citations (Scopus)

Targeting aPKC disables oncogenic signaling by both the EGFR and the proinflammatory cytokine TNFα in glioblastoma

Kusne, Y., Carrera-Silva, E. A., Perry, A. S., Rushing, E. J., Mandell, E. K., Dietrich, J. D., Errasti, A. E., Gibbs, D., Berens, M. E., Loftus, J. C., Hulme, C., Yang, W., Lu, Z., Aldape, K., Sanai, N., Rothlin, C. V. & Ghosh, S., Aug 12 2014, In : Science Signaling. 7, 338, ra75.

Research output: Contribution to journalArticle

Glioblastoma
Epidermal Growth Factor Receptor
Tumor Necrosis Factor-alpha
Cytokines
Tumors
61 Citations (Scopus)

T-helper 2 cytokines, transforming growth factor β1, and eosinophil products induce fibrogenesis and alter muscle motility in patients with eosinophilic esophagitis

Rieder, F., Nonevski, I., Ma, J., Ouyang, Z., West, G., Protheroe, C., Depetris, G., Schirbel, A., Lapinski, J., Goldblum, J., Bonfield, T., Lopez, R., Harnett, K., Lee, J., Hirano, I., Falk, G., Biancani, P. & Fiocchi, C., 2014, In : Gastroenterology. 146, 5

Research output: Contribution to journalArticle

Eosinophilic Esophagitis
Transforming Growth Factors
Eosinophils
Cytokines
Muscles