Biochemistry and Molecular Biology

Research Output

Transcriptional regulation of the MUC1 mucin gene in colon carcinoma cells by a soluble factor. Identification of a regulatory element

Shirotani, K., Taylor-Papadimitriou, J., Gendler, S. J. & Irimura, T., Jan 1 1994, In : Journal of Biological Chemistry. 269, 21, p. 15030-15035 6 p.

Research output: Contribution to journalArticle

27 Scopus citations

Transgenic mice expressing a human poliovirus receptor: A new model for poliomyelitis

Ren, R., Costantini, F., Gorgacz, E. J., Lee, J. J. & Racaniello, V. R., Oct 19 1990, In : Cell. 63, 2, p. 353-362 10 p.

Research output: Contribution to journalArticle

296 Scopus citations

Transgenic MUC1 Interacts with Epidermal Growth Factor Receptor and Correlates with Mitogen-activated Protein Kinase Activation in the Mouse Mammary Gland

Schroeder, J. A., Thompson, M. C., Gardner, M. M. & Gendler, S. J., Apr 20 2001, In : Journal of Biological Chemistry. 276, 16, p. 13057-13064 8 p.

Research output: Contribution to journalArticle

271 Scopus citations

Transmembrane peptides as unique tools to demonstrate the in vivo action of a cross-class GPCR heterocomplex

Lee, L. T. O., Ng, S. Y. L., Chu, J. Y. S., Sekar, R., Harikumar, K. G., Miller, L. J. & Chow, B. K. C., Jun 2014, In : FASEB Journal. 28, 6, p. 2632-2644 13 p.

Research output: Contribution to journalArticle

30 Scopus citations

Transmembrane segment IV contributes a functionally important interface for oligomerization of the class II G protein-coupled secretin receptor

Harikumar, K. G., Pinon, D. I. & Miller, L. J., Oct 19 2007, In : Journal of Biological Chemistry. 282, 42, p. 30363-30372 10 p.

Research output: Contribution to journalArticle

74 Scopus citations

Transmembrane segment peptides can disrupt cholecystokinin receptor oligomerization without affecting receptor function

Harikumar, K. G., Dong, M., Cheng, Z., Pinon, D. I., Lybrand, T. P. & Miller, L. J., Dec 12 2006, In : Biochemistry. 45, 49, p. 14706-14716 11 p.

Research output: Contribution to journalArticle

29 Scopus citations

TROY (TNFRSF19) is overexpressed in advanced glial tumors and promotes glioblastoma cell invasion via Pyk2-Rac1 signaling

Paulino, V. M., Yang, Z., Kloss, J., Ennis, M. J., Armstrong, B. A., Loftus, J. C. & Tran, N. L., Nov 2010, In : Molecular Cancer Research. 8, 11, p. 1558-1567 10 p.

Research output: Contribution to journalArticle

45 Scopus citations

TROY (TNFRSF19) promotes glioblastoma survival signaling and therapeutic resistance

Loftus, J. C., Dhruv, H., Tuncali, S., Kloss, J., Yang, Z., Schumacher, C. A., Cao, B., Williams, B. O., Eschbacher, J. M., Ross, J. T. D. & Tran, N. L., Aug 1 2013, In : Molecular Cancer Research. 11, 8, p. 865-874 10 p.

Research output: Contribution to journalArticle

29 Scopus citations

TROY signals through JAK1-STAT3 to promote glioblastoma cell migration and resistance

Ding, Z., Kloss, J. M., Tuncali, S., Tran, N. L. & Loftus, J. C., Sep 2020, In : Neoplasia (United States). 22, 9, p. 352-364 13 p.

Research output: Contribution to journalArticle

Open Access

Tumor-associated carbohydrate antigens: A possible avenue for cancer prevention

Xu, Y., Sette, A., Sidney, J., Gendler, S. J. & Franco, A., Aug 1 2005, In : Immunology and Cell Biology. 83, 4, p. 440-448 9 p.

Research output: Contribution to journalArticle

55 Scopus citations

Tumor eosinophil infiltration and improved survival of colorectal cancer patients: Iowa Women's Health Study

Prizment, A. E., Vierkant, R. A., Smyrk, T. C., Tillmans, L. S., Lee, J. J., Sriramarao, P., Nelson, H. H., Lynch, C. F., Thibodeau, S. N., Church, T. R., Cerhan, J. R., Anderson, K. E. & Limburg, P. J., May 1 2016, In : Modern Pathology. 29, 5, p. 516-527 12 p.

Research output: Contribution to journalArticle

18 Scopus citations

Tumor necrosis factor-like weak inducer of apoptosis stimulation of glioma cell survival is dependent on Akt2 function

Fortin, S. P., Ennis, M. J., Savitch, B. A., Carpentieri, D., McDonough, W. S., Winkles, J. A., Loftus, J. C., Kingsley, C., Hostetter, G. & Tran, N. L., Nov 2009, In : Molecular Cancer Research. 7, 11, p. 1871-1881 11 p.

Research output: Contribution to journalArticle

43 Scopus citations

Two highly homologous ribonuclease genes expressed in mouse eosinophils identify a larger subgroup of the mammalian ribonuclease superfamily

Larson, K. A., Olson, E. V., Madden, B. J., Gleich, G. J., Lee, N. A. & Lee, J. J., Oct 29 1996, In : Proceedings of the National Academy of Sciences of the United States of America. 93, 22, p. 12370-12375 6 p.

Research output: Contribution to journalArticle

67 Scopus citations

Tyrosines in the MUC1 cytoplasmic tail modulate transcription via the extracellular signal-regulated kinase 1/2 and nuclear factor-κB pathways

Thompson, E. J., Shanmugam, K., Hattrup, C. L., Kotlarczyk, K. L., Gutierrez, A., Bradley, J. M., Mukherjee, P. & Gendler, S. J., Jul 2006, In : Molecular Cancer Research. 4, 7, p. 489-497 9 p.

Research output: Contribution to journalArticle

33 Scopus citations

Tyzzer's disease in two coyotes.

Marler, R. J. & Cook, J. E., Nov 1 1976, In : Journal of the American Veterinary Medical Association. 169, 9, p. 940-941 2 p.

Research output: Contribution to journalArticle

11 Scopus citations

Update on clinical and immunological features of eosinophilic gastrointestinal diseases

Masterson, J. C., Furuta, G. T. & Lee, J. J., Oct 1 2011, In : Current Opinion in Gastroenterology. 27, 6, p. 515-522 8 p.

Research output: Contribution to journalReview article

29 Scopus citations

Use of colloidal gold to examine fibrinogen binding to human platelets

Loftus, J. C. & Albrecht, R. M., Dec 1 1983, In : Scanning Electron Microscopy. 1983, 4, p. 1995-1999 5 p.

Research output: Contribution to journalArticle

11 Scopus citations

Use of Correlative Microscopy with Colloidal Gold Labeling to Demonstrate Platelet Receptor Distribution and Movement

Albrecht, R. M., Olorundare, O. E., Simmons, S. R., Loftus, J. C. & Mosher, D. F., Jan 1 1992, In : Methods in enzymology. 215, C, p. 456-479 24 p.

Research output: Contribution to journalArticle

10 Scopus citations

Use of embryonic stem cells to study mutations affecting postimplantation development in the mouse.

Robertson, E. J., Conlon, F. L., Barth, K. S., Costantini, F. & Lee, J. J., 1992, In : Ciba Foundation symposium. 165, p. 237-250; discussion 250-255

Research output: Contribution to journalReview article

19 Scopus citations

Use of fluorescence indicators in receptor ligands.

Harikumar, K. G. & Miller, L. J., 2009, In : Methods in molecular biology (Clifton, N.J.). 552, p. 279-291 13 p.

Research output: Contribution to journalArticle

2 Scopus citations

Use of multidimensional fluorescence resonance energy transfer to establish the orientation of cholecystokinin docked at the type A cholecystokinin receptor

Harikumar, K. G., Gao, F., Pinon, D. I. & Miller, L. J., Sep 9 2008, In : Biochemistry. 47, 36, p. 9574-9581 8 p.

Research output: Contribution to journalArticle

8 Scopus citations
19 Scopus citations

Use of zonal centrifugation method for the preparation of μ-opioid receptor enriched membranes from bovine corpus striatum

Sastry, K. V. H., Harikumar, K. G., Sailaja, P. & Janardana Sarma, M. K., Jun 6 1997, In : Journal of Neuroscience Methods. 74, 1, p. 45-52 8 p.

Research output: Contribution to journalArticle

2 Scopus citations

Vaccination with allogeneic dendritic cells fused to carcinoma cells induces antitumor immunity in MUC1 transgenic mice

Tanaka, Y., Koido, S., Chen, D., Gendler, S. J., Kufe, D. & Gong, J., Jan 1 2001, In : Clinical Immunology. 101, 2, p. 192-200 9 p.

Research output: Contribution to journalArticle

57 Scopus citations

Validation of a mouse adhesion reduction model using Seprafilm®

Morse, A. N., Hammer, R. A., Cornella, J. L. & Loftus, J. C., Dec 2005, In : Journal of Gynecologic Surgery. 21, 4, p. 147-153 7 p.

Research output: Contribution to journalArticle

3 Scopus citations

Variation in Endoscopic Activity Assessment and Endoscopy Score Validation in Adults With Eosinophilic Esophagitis

International EEsAI Study Group, Jul 2019, In : Clinical Gastroenterology and Hepatology. 17, 8, p. 1477-1488.e10

Research output: Contribution to journalArticle

2 Scopus citations

Verapamil and its derivative trigger apoptosis through glutathione extrusion by multidrug resistance protein MRP1

Trompier, D., Chang, X. B., Barattin, R., Du Moulinet D'Hardemare, A., Di Pietro, A. & Baubichon-Cortay, H., Jul 15 2004, In : Cancer research. 64, 14, p. 4950-4956 7 p.

Research output: Contribution to journalArticle

97 Scopus citations

Vesicle-associated membrane protein 7-mediated eosinophil degranulation promotes allergic airway inflammation in mice

Willetts, L., Felix, L. C., Jacobsen, E. A., Puttagunta, L., Condjella, R. M., Zellner, K. R., Ochkur, S. I., Kim, J. D., Luo, H., Lee, N. A., Lee, J. J., Moqbel, R. & Lacy, P., Dec 1 2018, In : Communications Biology. 1, 1, 83.

Research output: Contribution to journalArticle

Open Access
3 Scopus citations

What is the functional role of the thalidomide binding protein cereblon?

Chang, X. B. & Keith Stewart, A., Dec 1 2011, In : International Journal of Biochemistry and Molecular Biology. 2, 3, p. 287-294 8 p.

Research output: Contribution to journalReview article

45 Scopus citations

Wnt5a promotes Frizzled-4 signalosome assembly by stabilizing cysteine-rich domain dimerization

DeBruine, Z. J., Ke, J., Harikumar, K. G., Gu, X., Borowsky, P., Williams, B. O., Xu, W., Miller, L. J., Xu, H. E. & Melcher, K., 2017, In : Genes and Development. 31, 9, p. 916-926 11 p.

Research output: Contribution to journalArticle

23 Scopus citations

Workshop report from the national institutes of health taskforce on the research needs of eosinophil-associated diseases (TREAD)

Bochner, B. S., Book, W., Busse, W. W., Butterfield, J., Furuta, G. T., Gleich, G. J., Klion, A. D., Lee, J. J., Leiferman, K. M., Minnicozzi, M., Moqbel, R., Rothenberg, M. E., Schwartz, L. B., Simon, H. U., Wechsler, M. E. & Weller, P. F., Sep 2012, In : Journal of Allergy and Clinical Immunology. 130, 3, p. 587-596 10 p.

Research output: Contribution to journalArticle

36 Scopus citations

β Integrins participate in the hypertrophic response of rat ventricular myocytes

Ross, R. S., Pham, C., Shai, S. Y., Goldhaber, J. I., Fenczik, C., Glembotski, C. C., Ginsberg, M. H. & Loftus, J. C., Jun 15 1998, In : Circulation research. 82, 11, p. 1160-1172 13 p.

Research output: Contribution to journalArticle

Open Access
151 Scopus citations