• 39889 Citations
  • 101 Scopus h-Index
1976 …2021

Research output per year

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Research Output

2008

Serum biomarker profile associated with high bone turnover and BMD in postmenopausal women

Bhattacharyya, S., Siegel, E. R., Achenbach, S. J., Khosla, S. & Suva, L. J., Jul 2008, In : Journal of Bone and Mineral Research. 23, 7, p. 1106-1117 12 p.

Research output: Contribution to journalArticle

42 Scopus citations
50 Scopus citations

The skeletal response to estrogen is impaired in female but not in male steroid receptor coactivator (SRC)-1 knock out mice

Mödder, U. I., Sanyal, A., Xu, J., O'Malley, B. W., Spelsberg, T. C. & Khosla, S., Feb 2008, In : Bone. 42, 2, p. 414-421 8 p.

Research output: Contribution to journalArticle

18 Scopus citations

Use of renal function measurements for assessing fracture risk in postmenopausal women

McCarthy, J. T., Rule, A. D., Achenbach, S. J., Bergstralh, E. J., Khosla, S. & Melton, L. J., 2008, In : Mayo Clinic Proceedings. 83, 11, p. 1231-1239 9 p.

Research output: Contribution to journalArticle

9 Scopus citations
2007

Are the endocrine society's clinical practice guidelines on androgen therapy in women misguided? A commentary-response

Wierman, M., Basson, R., Davis, S., Khosla, S., Miller, K., Rosner, W. & Santoro, N., Nov 2007, In : Journal of Sexual Medicine. 4, 6, p. 1782-1783 2 p.

Research output: Contribution to journalArticle

6 Scopus citations

Bisphosphonate-associated osteonecrosis of the jaw: Report of a Task Force of the American Society for Bone and Mineral Research

Khosla, S., Burr, D., Cauley, J., Dempster, D. W., Ebeling, P. R., Felsenberg, D., Gagel, R. F., Gilsanz, V., Guise, T., Koka, S., McCauley, L. K., McGowan, J., McKee, M. D., Mohla, S., Pendrys, D. G., Raisz, L. G., Ruggiero, S. L., Shafer, D. M., Shum, L., Silverman, S. L. & 4 others, Van Poznak, C. H., Watts, N., Woo, S. B. & Shane, E., Oct 2007, In : Journal of Bone and Mineral Research. 22, 10, p. 1479-1491 13 p.

Research output: Contribution to journalArticle

1176 Scopus citations

Characterization of circulating osteoblast lineage cells in humans

Eghbali-Fatourechi, G. Z., Mödder, U. I. L., Charatcharoenwitthaya, N., Sanyal, A., Undale, A. H., Clowes, J. A., Tarara, J. E. & Khosla, S., May 2007, In : Bone. 40, 5, p. 1370-1377 8 p.

Research output: Contribution to journalArticle

108 Scopus citations

Contribution of in vivo structural measurements and load/strength ratios to the determination of forearm fracture risk in postmenopausal women

Melton, L. J., Riggs, B. L., Van Lenthe, G. H., Achenbach, S. J., Müller, R., Bouxsein, M. L., Amin, S., Atkinson, E. J. & Khosla, S., Sep 2007, In : Journal of Bone and Mineral Research. 22, 9, p. 1442-1448 7 p.

Research output: Contribution to journalArticle

147 Scopus citations

Corrigendum to "Characterization of circulating osteoblast lineage cells in humans" [Bone 40 (2007) 1370-1377] (DOI: 10.1016/j.bone.2006.12.064)

Eghbali-Fatourechi, G. Z., Mödder, U. I. L., Charatcharoenwitthaya, N., Sanyal, A., Undale, A. H., Clowes, J. A., Tarara, J. E. & Khosla, S., Oct 2007, In : Bone. 41, 4, p. 741 1 p.

Research output: Contribution to journalArticle

1 Scopus citations

Effect of 2 years of testosterone replacement on insulin secretion, insulin action, glucose effectiveness, hepatic insulin clearance, and postprandial glucose turnover in elderly men

Basu, R., Dalla Man, C., Campioni, M., Basu, A., Nair, K. S., Jensen, M. D., Khosla, S., Klee, G., Toffolo, G., Cobelli, C. & Rizza, R. A., Aug 2007, In : Diabetes Care. 30, 8, p. 1972-1978 7 p.

Research output: Contribution to journalArticle

68 Scopus citations

Effect of blockade of TNF-α and interleukin-1 action on bone resorption in early postmenopausal women

Charatcharoenwitthaya, N., Khosla, S., Atkinson, E. J., McCready, L. K. & Riggs, B. L., May 2007, In : Journal of Bone and Mineral Research. 22, 5, p. 724-729 6 p.

Research output: Contribution to journalArticle

149 Scopus citations

Effects of loss of classical estrogen response element signaling on bone in male mice

Syed, F. A., Fraser, D. G., Spelsberg, T. C., Rosen, C. J., Krust, A., Chambon, P., Jameson, J. L. & Khosla, S., Apr 2007, In : Endocrinology. 148, 4, p. 1902-1910 9 p.

Research output: Contribution to journalArticle

22 Scopus citations

Effects of testosterone and estradiol on cutaneous vasodilation during local warming in older men

Sokolnicki, L. A., Khosla, S. & Charkoudian, N., Nov 2007, In : American Journal of Physiology - Endocrinology and Metabolism. 293, 5

Research output: Contribution to journalArticle

10 Scopus citations

Erratum: Two years of treatment with dehydroepiandrosterone does not improve insulin secretion, insulin action, or postprandial glucose turnover in elderly men or women (Diabetes (2007) 56, (753-766))

Basu, R., Man, C. D., Campioni, M., Basu, A., Nair, K. S., Jensen, M. D., Khosla, S., Klee, G., Toffolo, G., Cobelli, C. & Rizza, R. A., May 2007, In : Diabetes. 56, 5, p. 1486 1 p.

Research output: Contribution to journalArticle

1 Scopus citations

Estrogen therapy and coronary-artery calcification [3]

Hofbauer, L. C., Khosla, S. & Schoppet, M., Sep 20 2007, In : New England Journal of Medicine. 357, 12, p. 1253-1254 2 p.

Research output: Contribution to journalArticle

2 Scopus citations

High serum IGFBP-2 is predictive of increased bone turnover in aging men and women

Amin, S., Riggs, B. L., Melton, L. J., Achenbach, S. J., Atkinson, E. J. & Khosla, S., Jun 2007, In : Journal of Bone and Mineral Research. 22, 6, p. 799-807 9 p.

Research output: Contribution to journalArticle

55 Scopus citations

High-trauma fractures and bone mineral density

Khosla, S., Nov 28 2007, In : Journal of the American Medical Association. 298, 20, p. 2418-2419 2 p.

Research output: Contribution to journalArticle

1 Scopus citations

Osteopenia

Khosla, S. & Melton, L. J., May 31 2007, In : New England Journal of Medicine. 356, 22, p. 2293-2300 8 p.

Research output: Contribution to journalArticle

66 Scopus citations

Remodeling and vascular spaces in bone

Eriksen, E. F., Eghbali-Fatourechi, G. Z. & Khosla, S., Jan 2007, In : Journal of Bone and Mineral Research. 22, 1, p. 1-6 6 p.

Research output: Contribution to journalArticle

119 Scopus citations

Structural determinants of vertebral fracture risk

Mellon, L. J., Riggs, B. L., Keaveny, T. M., Achenbach, S. J., Hoffmann, P. F., Camp, J. J., Rouleau, P. A., Bouxsein, M. L., Amin, S., Atkinson, E. J., Robb, R. A. & Khosla, S., Dec 2007, In : Journal of Bone and Mineral Research. 22, 12, p. 1885-1892 8 p.

Research output: Contribution to journalArticle

140 Scopus citations

Two years of treatment with dehydroepiandrosterone does not improve insulin secretion, insulin action, or postprandial glucose turnover in elderly men or women

Basu, R., Man, C. D., Campioni, M., Basu, A., Nair, K. S., Jensen, M. D., Khosla, S., Klee, G., Toffolo, G., Cobelli, C. & Rizza, R. A., Mar 2007, In : Diabetes. 56, 3, p. 753-766 14 p.

Research output: Contribution to journalArticle

45 Scopus citations
2006

{A figure is presented} Long-term fracture risk among women with proven endometriosis

Melton, L. J., Leibson, C. L., Good, A. E., Achenbach, S. J., Oberg, A. L. & Khosla, S., Dec 2006, In : Fertility and Sterility. 86, 6, p. 1576-1583 8 p.

Research output: Contribution to journalArticle

2 Scopus citations

Age- and sex-specific differences in the factor of risk for vertebral fracture: A population-based study using QCT

Bouxsein, M. L., Melton, L. J., Riggs, B. L., Muller, J., Atkinson, E. J., Oberg, A. L., Robb, R. A., Camp, J. J., Rouleau, P. A., McCollough, C. H. & Khosla, S., Sep 2006, In : Journal of Bone and Mineral Research. 21, 9, p. 1475-1482 8 p.

Research output: Contribution to journalArticle

113 Scopus citations

Bone fragility in men - Where are we?

Seeman, E., Bianchi, G., Khosla, S., Kanis, J. A. & Orwoll, E., Nov 2006, In : Osteoporosis International. 17, 11, p. 1577-1583 7 p.

Research output: Contribution to journalArticle

76 Scopus citations

Bone turnover across the menopause transition: Correlations with inhibins and follicle-stimulating hormone

Perrien, D. S., Achenbach, S. J., Bledsoe, S. E., Walser, B., Suva, L. J., Khosla, S. & Gaddy, D., May 2006, In : Journal of Clinical Endocrinology and Metabolism. 91, 5, p. 1848-1854 7 p.

Research output: Contribution to journalArticle

83 Scopus citations

Circulating cells with osteogenic potential

Khosla, S. & Eghbali-Fatourechi, G. Z., Apr 2006, In : Annals of the New York Academy of Sciences. 1068, 1, p. 489-497 9 p.

Research output: Contribution to journalArticle

69 Scopus citations

Clinical practice guideline: Androgen therapy in women: An Endocrine Society clinical practice guideline

Wierman, M. E., Basson, R., Davis, S. R., Khosla, S., Miller, K. K., Rosner, W. & Santoro, N., Oct 2006, In : Journal of Clinical Endocrinology and Metabolism. 91, 10, p. 3697-3710 14 p.

Research output: Contribution to journalArticle

241 Scopus citations

DHEA in elderly women and DHEA or testosterone in elderly men

Nair, K. S., Rizza, R. A., O'Brien, P., Dhatariya, K., Short, K. R., Nehra, A., Vittone, J. L., Klee, G. G., Basu, A., Basu, R., Cobelli, C., Toffolo, G., Man, C. D., Tindall, D. J., Melton, L. J., Smith, G. E., Khosla, S. & Jensen, M. D., Oct 19 2006, In : New England Journal of Medicine. 355, 16, p. 1647-1659 13 p.

Research output: Contribution to journalArticle

426 Scopus citations

Does reduced skeletal loading account for age-related bone loss?

Melton, L. J., Riggs, B. L., Achenbach, S. J., Amin, S., Camp, J. J., Rouleau, P. A., Robb, R. A., Oberg, A. L. & Khosla, S., Dec 2006, In : Journal of Bone and Mineral Research. 21, 12, p. 1847-1855 9 p.

Research output: Contribution to journalArticle

40 Scopus citations
34 Scopus citations

Effects of sex and age on bone microstructure at the ultradistal radius: A population-based noninvasive in vivo assessment

Khosla, S., Riggs, B. L., Atkinson, E. J., Oberg, A. L., McDaniel, L. J., Holets, M., Peterson, J. M. & Melton, L. J., Jan 2006, In : Journal of Bone and Mineral Research. 21, 1, p. 124-131 8 p.

Research output: Contribution to journalArticle

386 Scopus citations

Estrogen receptor beta: the antimechanostat?

Khosla, S., Modder, U. I., Moedder, U. I. & Syed, F. A., Feb 1 2006, In : Bone. 38, 2

Research output: Contribution to journalArticle

1 Scopus citations

Estrogen receptor isoform-specific regulation of the retinoblastoma-binding protein 1 (RBBP1) gene: Roles of AF1 and enhancer elements

Monroe, D. G., Secreto, F. J., Hawse, J. R., Subramaniam, M., Khosla, S. & Spelsberg, T. C., Sep 29 2006, In : Journal of Biological Chemistry. 281, 39, p. 28596-28604 9 p.

Research output: Contribution to journalArticle

19 Scopus citations

Hormonal and biochemical determinants of trabecular microstructure at the ultradistal radius in women and men

Khosla, S., Melton, L. J., Achenbach, S. J., Oberg, A. L. & Riggs, B. L., Mar 2006, In : Journal of Clinical Endocrinology and Metabolism. 91, 3, p. 885-891 7 p.

Research output: Contribution to journalArticle

81 Scopus citations

Incidence of primary hyperparathyroidism in Rochester, Minnesota, 1993-2001: An update on the changing epidemiology of the disease

Wermers, R. A., Khosla, S., Atkinson, E. J., Achenbach, S. J., Oberg, A. L., Grant, C. S. & Melton, L. J., Jan 2006, In : Journal of Bone and Mineral Research. 21, 1, p. 171-177 7 p.

Research output: Contribution to journalArticle

252 Scopus citations

Letter to the editor [2]

Khosla, S., Moedder, U. I. & Syed, F. A., Feb 2006, In : Bone. 38, 2, p. 289 1 p.

Research output: Contribution to journalArticle

2 Scopus citations

Population-based analysis of the relationship of whole bone strength indices and fall-related loads to age- and sex-specific patterns of hip and wrist fractures

Riggs, B. L., Melton, L. J., Robb, R. A., Camp, J. J., Atkinson, E. J., Oberg, A. L., Rouleau, P. A., McCollough, C. H., Khosla, S. & Bouxsein, M. L., Feb 2006, In : Journal of Bone and Mineral Research. 21, 2, p. 315-323 9 p.

Research output: Contribution to journalArticle

79 Scopus citations

Sex Steroid Effects on Bone Metabolism

Monroe, D. G., Spelsberg, T. C. & Khosla, S., 2006, Dynamics of Bone and Cartilage Metabolism. Elsevier Inc., p. 327-343 17 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

2 Scopus citations

Systemic assessments utilizing saliva: Part 2 - Osteoporosis and use of saliva to measure bone turnover

Koka, S., Forde, M. D. & Khosla, S., Jan 2006, In : International Journal of Prosthodontics. 19, 1, p. 53-60 8 p.

Research output: Contribution to journalArticle

16 Scopus citations

The classical estrogen receptor transcriptional pathway: Implications in human osteoblasts

Monroe, D. G., Secreto, F. J., Khosla, S. & Spelsberg, T. C., 2006, In : Clinical Reviews in Bone and Mineral Metabolism. 4, 2, p. 129-140 12 p.

Research output: Contribution to journalArticle

1 Scopus citations
2005
6 Scopus citations

Bone marrow stromal cells express two distinct splice variants of ER-α that are regulated by estrogen

Sanyal, A., Riggs, B. L., Spelsberg, T. C. & Khosla, S., Jan 1 2005, In : Journal of Cellular Biochemistry. 94, 1, p. 88-97 10 p.

Research output: Contribution to journalArticle

10 Scopus citations

Circulating osteoblast-lineage cells [4] (multiple letters)

Sata, M., Tanaka, K., Nagai, R., Eghbali-Fatourechi, G. Z. & Khosla, S., Aug 18 2005, In : New England Journal of Medicine. 353, 7, p. 737-738 2 p.

Research output: Contribution to journalArticle

17 Scopus citations

Circulating osteoblast-lineage cells in humans

Eghbali-Fatourechi, G. Z., Lamsam, J., Fraser, D., Nagel, D., Riggs, B. L. & Khosla, S., May 12 2005, In : New England Journal of Medicine. 352, 19, p. 1959-1966 8 p.

Research output: Contribution to journalArticle

289 Scopus citations
88 Scopus citations

Estrogen receptor α and β heterodimers exert unique effects on estrogen- and tamoxifen-dependent gene expression in human U2Os osteosarcoma cells

Monroe, D. G., Secreto, F. J., Subramaniam, M., Getz, B. J., Khosla, S. & Spelsberg, T. C., Jun 2005, In : Molecular Endocrinology. 19, 6, p. 1555-1568 14 p.

Research output: Contribution to journalArticle

109 Scopus citations

Evaluation of a prediction model for long-term fracture risk

Melton, L. J., Atkinson, E. J., Khosla, S., Oberg, A. L. & Lawrence Riggs, B., Apr 2005, In : Journal of Bone and Mineral Research. 20, 4, p. 551-556 6 p.

Research output: Contribution to journalArticle

25 Scopus citations

Magic bullets to kill nasty osteoclasts

Khosla, S., Aug 2005, In : Endocrinology. 146, 8, p. 3233-3234 2 p.

Research output: Contribution to journalArticle

4 Scopus citations