• 39889 Citations
  • 101 Scopus h-Index
1976 …2021

Research output per year

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Research Output

2012

Sclerostin levels during growth in children

Kirmani, S., Amin, S., McCready, L. K., Atkinson, E. J., Melton, L. J., Müller, R. & Khosla, S., Mar 2012, In : Osteoporosis International. 23, 3, p. 1123-1130 8 p.

Research output: Contribution to journalArticle

52 Scopus citations
20 Scopus citations
67 Scopus citations

TGF-β mediates suppression of adipogenesis by estradiol through connective tissue growth factor induction

Kumar, A., Ruan, M., Clifton, K., Syed, F., Khosla, S. & Oursler, M. J., Jan 2012, In : Endocrinology. 153, 1, p. 254-263 10 p.

Research output: Contribution to journalArticle

25 Scopus citations
2011

Association of hip strength estimates by finite-element analysis with fractures in women and men

Amin, S., Kopperdhal, D. L., Melton, L. J., Achenbach, S. J., Therneau, T. M., Riggs, B. L., Keaveny, T. M. & Khosla, S., Jul 2011, In : Journal of Bone and Mineral Research. 26, 7, p. 1593-1600 8 p.

Research output: Contribution to journalArticle

70 Scopus citations

Bone microstructural changes revealed by high-resolution peripheral quantitative computed tomography imaging and elevated DKK1 and MIP-1α levels in patients with MGUS

Ng, A. C., Khosla, S., Charatcharoenwitthaya, N., Kumar, S. K., Achenbach, S. J., Holets, M. F., McCready, L. K., Melton, L. J., Kyle, R. A., Rajkumar, S. V. & Drake, M. M., Dec 15 2011, In : Blood. 118, 25, p. 6529-6534 6 p.

Research output: Contribution to journalArticle

44 Scopus citations

Corrigendum to "Circulating osteogenic cells: Characterization and relationship to rates of bone loss in postmenopausal women" [Bone 47 (2010) 83-92]

Undale, A., Srinivasan, B., Drake, M. M., McCready, L., Atkinson, E., Peterson, J., Riggs, B. L., Amin, S., Modder, U. I. & Khosla, S., Mar 1 2011, In : Bone. 48, 3, p. 671 1 p.

Research output: Contribution to journalArticle

Corrigendum to "Letter to the Editor" [Bone 38 (2006) 289]

Khosla, S., Modder, U. I. & Syed, F. A., Mar 1 2011, In : Bone. 48, 3, p. 670 1 p.

Research output: Contribution to journalArticle

Determinants of forearm strength in postmenopausal women

Melton, L. J., Riggs, B. L., Müller, R., Achenbach, S. J., Christen, D., Atkinson, E. J., Amin, S. & Khosla, S., Dec 2011, In : Osteoporosis International. 22, 12, p. 3047-3054 8 p.

Research output: Contribution to journalArticle

4 Scopus citations

Distinct effects of loss of classical estrogen receptor signaling versus complete deletion of estrogen receptor alpha on bone

Syed, F. A., Fraser, D. G., Monroe, D. G. & Khosla, S., Aug 2011, In : Bone. 49, 2, p. 208-216 9 p.

Research output: Contribution to journalArticle

20 Scopus citations

Effects of estrogen on osteoprogenitor cells and cytokines/bone-regulatory factors in postmenopausal women

Mödder, U. I., Roforth, M. M., Hoey, K., McCready, L. K., Peterson, J. M., Monroe, D. G., Oursler, M. J. & Khosla, S., Aug 2011, In : Bone. 49, 2, p. 202-207 6 p.

Research output: Contribution to journalArticle

55 Scopus citations

Effects of intermittent parathyroid hormone treatment on osteoprogenitor cells in postmenopausal women

Drake, M. M., Srinivasan, B., Mödder, U. I., Ng, A. C., Undale, A. H., Roforth, M. M., Peterson, J. M., McCready, L. K., Riggs, B. L. & Khosla, S., Sep 2011, In : Bone. 49, 3, p. 349-355 7 p.

Research output: Contribution to journalArticle

30 Scopus citations

Effects of physiological variations in circulating insulin levels on bone turnover in humans

Basu, R., Peterson, J., Rizza, R. & Khosla, S., May 2011, In : Journal of Clinical Endocrinology and Metabolism. 96, 5, p. 1450-1455 6 p.

Research output: Contribution to journalArticle

41 Scopus citations

Effects of suppression of follicle-stimulating hormone secretion on bone resorption markers in postmenopausal women

Drake, M. M., McCready, L. K., Hoey, K. A., Atkinson, E. J. & Khosla, S., May 2011, In : Obstetrical and Gynecological Survey. 66, 5, p. 289-290 2 p.

Research output: Contribution to journalArticle

Emerging therapeutic opportunities for skeletal restoration

Kawai, M., Mödder, U. I., Khosla, S. & Rosen, C. J., Feb 2011, In : Nature Reviews Drug Discovery. 10, 2, p. 141-156 16 p.

Research output: Contribution to journalArticle

87 Scopus citations

Estrogen inhibits Dlk1/FA1 production: A potential mechanism for estrogen effects on bone turnover

Abdallah, B. M., Bay-Jensen, A. C., Srinivasan, B., Tabassi, N. C., Garnero, P., Delaissé, J. M., Khosla, S. & Kassem, M., Oct 2011, In : Journal of Bone and Mineral Research. 26, 10, p. 2548-2551 4 p.

Research output: Contribution to journalArticle

15 Scopus citations

Forum on aging and skeletal health: Summary of the proceedings of an ASBMR workshop

Khosla, S., Bellido, T. M., Drezner, M. K., Gordon, C. M., Harris, T. B., Kiel, D. P., Kream, B. E., Leboff, M. S., Lian, J. B., Peterson, C. A., Rosen, C. J., Williams, J. P., Winer, K. K. & Sherman, S. S., Nov 2011, In : Journal of Bone and Mineral Research. 26, 11, p. 2565-2578 14 p.

Research output: Contribution to journalArticle

19 Scopus citations

Fracture risk in men with prostate cancer: A population-based study

Melton, L. J., Lieber, M. M., Atkinson, E. J., Achenbach, S. J., Zincke, H., Therneau, T. M. & Khosla, S., Aug 2011, In : Journal of Bone and Mineral Research. 26, 8, p. 1808-1815 8 p.

Research output: Contribution to journalArticle

28 Scopus citations

Getting to the bare bones of fertility

Khosla, S. & Rosen, C., 2011, In : Nature Medicine. 17, 5, p. 550-551 2 p.

Research output: Contribution to journalArticle

1 Scopus citations

Human immunodeficiency virus envelope protein Gp120 induces proliferation but not apoptosis in osteoblasts at physiologic concentrations

Cummins, N. W., Klicpera, A., Sainski, A. M., Bren, G. D., Khosla, S., Westendorf, J. J. & Badley, A. D., Sep 12 2011, In : PLoS One. 6, 9, e24876.

Research output: Contribution to journalArticle

6 Scopus citations

Induction of fracture repair by mesenchymal cells derived from human embryonic stem cells or bone marrow

Undale, A., Fraser, D., Hefferan, T., Kopher, R. A., Herrick, J., Evans, G. L., Li, X., Kakar, S., Hayes, M., Atkinson, E., Yaszemski, M. J., Kaufman, D. S., Westendorf, J. J. & Khosla, S., Dec 2011, In : Journal of Orthopaedic Research. 29, 12, p. 1804-1811 8 p.

Research output: Contribution to journalArticle

19 Scopus citations

Is nitroglycerin a novel and inexpensive treatment for osteoporosis?

Khosla, S., Feb 23 2011, In : JAMA - Journal of the American Medical Association. 305, 8, p. 826-827 2 p.

Research output: Contribution to journalArticle

15 Scopus citations

Is vitamin D a determinant of muscle mass and strength?

Marantes, I., Achenbach, S. J., Atkinson, E. J., Khosla, S., Melton, L. J. & Amin, S., Dec 2011, In : Journal of Bone and Mineral Research. 26, 12, p. 2860-2871 12 p.

Research output: Contribution to journalArticle

69 Scopus citations

Nonoxidative free fatty acid disposal is greater in young women than men

Koutsari, C., Basu, R., Rizza, R. A., Nair, K. S., Khosla, S. & Jensen, M. D., Feb 2011, In : Journal of Clinical Endocrinology and Metabolism. 96, 2, p. 541-547 7 p.

Research output: Contribution to journalArticle

30 Scopus citations

Osteoporosis: Now and the future

Rachner, T. D., Khosla, S. & Hofbauer, L. C., Apr 9 2011, In : The Lancet. 377, 9773, p. 1276-1287 12 p.

Research output: Contribution to journalArticle

1084 Scopus citations

Osteoporosis Update From the 2010 Santa Fe Bone Symposium

Lewiecki, E. M., Bilezikian, J. P., Khosla, S., Marcus, R., McClung, M. R., Miller, P. D., Watts, N. B. & Maricic, M., Jan 2011, In : Journal of Clinical Densitometry. 14, 1, p. 1-21 21 p.

Research output: Contribution to journalArticle

19 Scopus citations

Regulation of circulating sclerostin levels by sex steroids in women and in men

Mödder, U. I., Clowes, J. A., Hoey, K., Peterson, J. M., McCready, L., Oursler, M. J., Riggs, B. L. & Khosla, S., Jan 2011, In : Journal of Bone and Mineral Research. 26, 1, p. 27-34 8 p.

Research output: Contribution to journalArticle

151 Scopus citations

Relation of age, gender, and bone mass to circulating sclerostin levels in women and men

Mödder, U. I., Hoey, K. A., Amin, S., McCready, L. K., Achenbach, S. J., Riggs, B. L., Melton, L. J. & Khosla, S., Feb 2011, In : Journal of Bone and Mineral Research. 26, 2, p. 373-379 7 p.

Research output: Contribution to journalArticle

243 Scopus citations

Relationship of testosterone and osteocalcin levels during growth

Kirmani, S., Atkinson, E. J., Melton, L. J., Riggs, B. L., Amin, S. & Khosla, S., Sep 2011, In : Journal of Bone and Mineral Research. 26, 9, p. 2212-2216 5 p.

Research output: Contribution to journalArticle

55 Scopus citations

Robust QCT/FEA models of proximal femur stiffness and fracture load during a sideways fall on the hip

Dragomir Daescu, M. D., Op Den Buijs, J., McEligot, S., Dai, Y., Entwistle, R. C., Salas, C., Melton, L. J., Bennet, K. E., Khosla, S. & Amin, S., Feb 2011, In : Annals of Biomedical Engineering. 39, 2, p. 742-755 14 p.

Research output: Contribution to journalArticle

140 Scopus citations

The bone and beyond: A shift in calcium

Khosla, S., Apr 2011, In : Nature Medicine. 17, 4, p. 430-431 2 p.

Research output: Contribution to journalArticle

19 Scopus citations

The oxysterol, 27-hydroxycholesterol, links cholesterol metabolism to bone homeostasis through its actions on the estrogen and liver X receptors

Nelson, E. R., DuSell, C. D., Wang, X., Howe, M. K., Evans, G., Michalek, R. D., Umetani, M., Rathmell, J. C., Khosla, S., Gesty-Palmer, D. & McDonnell, D. P., Dec 2011, In : Endocrinology. 152, 12, p. 4691-4705 15 p.

Research output: Contribution to journalArticle

62 Scopus citations

The unitary model for estrogen deficiency and the pathogenesis of osteoporosis: Is a revision needed?

Khosla, S., Melton, L. J. & Riggs, B. L., Mar 2011, In : Journal of Bone and Mineral Research. 26, 3, p. 441-451 11 p.

Research output: Contribution to journalArticle

183 Scopus citations

Towards a diagnostic and therapeutic consensus in male osteoporosis

Kanis, J. A., Bianchi, G., Bilezikian, J. P., Kaufman, J. M., Khosla, S., Orwoll, E. & Seeman, E., Nov 2011, In : Osteoporosis International. 22, 11, p. 2789-2798 10 p.

Research output: Contribution to journalArticle

86 Scopus citations

Trabecular bone deficits among Vietnamese immigrants

Melton, L. J., Marquez, M. A., McCready, L. K., Achenbach, S. J., Riggs, B. L., Amin, S. & Khosla, S., May 2011, In : Osteoporosis International. 22, 5, p. 1627-1631 5 p.

Research output: Contribution to journalArticle

1 Scopus citations

What do we tell our patients about calcium and vitamin D supplementation?

Khosla, S., Jan 2011, In : Journal of Clinical Endocrinology and Metabolism. 96, 1, p. 69-71 3 p.

Research output: Contribution to journalArticle

7 Scopus citations

Wnt10b activates the wnt, notch, and NFIκB pathways in u2os osteosarcoma cells

Mödder, U. I., Oursler, M. J., Khosla, S. & Monroe, D. G., May 2011, In : Journal of Cellular Biochemistry. 112, 5, p. 1392-1402 11 p.

Research output: Contribution to journalArticle

40 Scopus citations
2010

Age-dependence of femoral strength in white women and men

Keaveny, T. M., Kopperdahl, D. L., Melton, L. J., Hoffmann, P. F., Amin, S., Riggs, B. L. & Khosla, S., May 2010, In : Journal of Bone and Mineral Research. 25, 5, p. 994-1001 8 p.

Research output: Contribution to journalArticle

109 Scopus citations

Assessing forearm fracture risk in postmenopausal women

Melton, L. J., Christen, D., Riggs, B. L., Achenbach, S. J., Müller, R., Van Lenthe, G. H., Amin, S., Atkinson, E. J. & Khosla, S., Jul 2010, In : Osteoporosis International. 21, 7, p. 1161-1169 9 p.

Research output: Contribution to journalArticle

85 Scopus citations

Circulating osteogenic cells: Characterization and relationship to rates of bone loss in postmenopausal women

Undale, A., Srinivasan, B., Drake, M. M., McCready, L., Atkinson, E., Peterson, J., Riggs, B. L., Amin, S., Moedder, U. I. & Khosla, S., Jul 2010, In : Bone. 47, 1, p. 83-92 10 p.

Research output: Contribution to journalArticle

27 Scopus citations

Concise review: Insights from normal bone remodeling and stem cell-based therapies for bone repair

Khosla, S., Westendorf, J. J. & Mödder, U. I., Dec 2010, In : Stem Cells. 28, 12, p. 2124-2128 5 p.

Research output: Contribution to journalArticle

63 Scopus citations

Coronary endothelial dysfunction in humans is associated with coronary retention of osteogenic endothelial progenitor cells

Gössl, M., Mödder, U. I., Gulati, R., Rihal, C., Prasad, A., Loeffler, D., Lerman, L. O., Khosla, S. & Lerman, A., Dec 2010, In : European Heart Journal. 31, 23, p. 2909-2914 6 p.

Research output: Contribution to journalArticle

51 Scopus citations

Effects of chronic estrogen treatment on modulating age-related bone loss in female mice

Syed, F. A., Mödder, U. I., Roforth, M., Hensen, I., Fraser, D. G., Peterson, J. M., Oursler, M. J. & Khosla, S., Nov 2010, In : Journal of Bone and Mineral Research. 25, 11, p. 2438-2446 9 p.

Research output: Contribution to journalArticle

33 Scopus citations

Effects of estrogen and testosterone on resting energy expenditure in older men

Santosa, S., Khosla, S., McCready, L. K. & Jensen, M. D., Dec 2010, In : Obesity. 18, 12, p. 2392-2394 3 p.

Research output: Contribution to journalArticle

9 Scopus citations

Effects of parathyroid hormone treatment on circulating sclerostin levels in postmenopausal women

Drake, M. M., Srinivasan, B., Mödder, U. I., Peterson, J. M., McCready, L. K., Riggs, B. L., Dwyer, D., Stolina, M., Kostenuik, P. & Khosla, S., Nov 2010, In : Journal of Clinical Endocrinology and Metabolism. 95, 11, p. 5056-5062 7 p.

Research output: Contribution to journalArticle

193 Scopus citations

Effects of suppression of follicle-stimulating hormone secretion on bone resorption markers in postmenopausal women

Drake, M. M., McCready, L. K., Hoey, K. A., Atkinson, E. J. & Khosla, S., Nov 2010, In : Journal of Clinical Endocrinology and Metabolism. 95, 11, p. 5063-5068 6 p.

Research output: Contribution to journalArticle

63 Scopus citations

Fat tissue, aging, and cellular senescence

Tchkonia, T., Morbeck, D. E., Von Zglinicki, T., Van Deursen, J., Lustgarten, J., Scrable, H., Khosla, S., Jensen, M. D. & Kirkland, J. L., Oct 2010, In : Aging Cell. 9, 5, p. 667-684 18 p.

Research output: Contribution to journalArticle

426 Scopus citations

Female reproductive system and bone

Clarke, B. & Khosla, S., Nov 2010, In : Archives of Biochemistry and Biophysics. 503, 1, p. 118-128 11 p.

Research output: Contribution to journalArticle

94 Scopus citations

Human embryonic stem cell-derived CD34+ cells function as MSC progenitor cells

Kopher, R. A., Penchev, V. R., Islam, M. S., Hill, K. L., Khosla, S. & Kaufman, D. S., Oct 2010, In : Bone. 47, 4, p. 718-728 11 p.

Research output: Contribution to journalArticle

42 Scopus citations

Modulators of androgen and estrogen receptor activity

Clarke, B. & Khosla, S., 2010, In : Critical Reviews in Eukaryotic Gene Expression. 20, 4, p. 275-294 20 p.

Research output: Contribution to journalArticle

7 Scopus citations