• 40896 Citations
  • 102 Scopus h-Index
1980 …2020

Research output per year

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Research Output

Article

{A figure is presented} Long-term fracture risk among women with proven endometriosis

Melton, L. J., Leibson, C. L., Good, A. E., Achenbach, S. J., Oberg, A. L. & Khosla, S., Dec 1 2006, In : Fertility and Sterility. 86, 6, p. 1576-1583 8 p.

Research output: Contribution to journalArticle

2 Scopus citations

Abdominal aortic calcification, BMD, and bone microstructure: A population-based study

Chow, J. T., Khosla, S., Melton, L. J., Atkinson, E. J., Camp, J. J. & Kearns, A. E., Oct 1 2008, In : Journal of Bone and Mineral Research. 23, 10, p. 1601-1612 12 p.

Research output: Contribution to journalArticle

34 Scopus citations

Ability of circulating human hematopoietic lineage negative cells to support hematopoiesis

Peris, P., Roforth, M. M., Nicks, K. M., Fraser, D., Fujita, K., Jilka, R. L., Khosla, S. & McGregor, U., Jan 1 2015, In : Journal of Cellular Biochemistry. 116, 1, p. 58-66 9 p.

Research output: Contribution to journalArticle

2 Scopus citations

Abnormalities of parathyroid hormone secretion in elderly women that are reversible by short term therapy with 1,25-dihydroxyvitamin D3

Ledger, G. A., Burritt, M. F., Kao, P. C., O’fallon, W. M., Riggs, B. L. & Khosla, S., Jul 1994, In : Journal of Clinical Endocrinology and Metabolism. 79, 1, p. 211-216 6 p.

Research output: Contribution to journalArticle

72 Scopus citations

A bone structural basis for fracture risk in diabetes

Melton, L. J., Riggs, B. L., Leibson, C. L., Achenbach, S. J., Camp, J. J., Bouxsein, M. L., Atkinson, E. J., Robb, R. A. & Khosla, S., Dec 2008, In : Journal of Clinical Endocrinology and Metabolism. 93, 12, p. 4804-4809 6 p.

Research output: Contribution to journalArticle

110 Scopus citations

Accelerated osteocyte senescence and skeletal fragility in mice with type 2 diabetes

Eckhardt, B. A., Rowsey, J. L., Thicke, B. S., Fraser, D. G., O'Grady, K. L., Bondar, O. P., Hines, J. M., Singh, R. J., Thoreson, A. R., Rakshit, K., Lagnado, A. B., Passos, J. F., Vella, A., Matveyenko, A. V., Khosla, S., Monroe, D. G. & Farr, J. N., May 7 2020, In : JCI Insight. 5, 9, e135236.

Research output: Contribution to journalArticle

Open Access

ACTH AND INDOMETHACIN‐INDUCED ANTIDIURESIS IN LOW SALT BRATTLEBORO STRAIN RATS: INDUCTION AND ESCAPE

Khosla, S., Kinter, L. B., Zusman, R. & Beeuwkes, R., Oct 1982, In : Annals of the New York Academy of Sciences. 394, 1, p. 265-269 5 p.

Research output: Contribution to journalArticle

Addressing the Crisis in the Treatment of Osteoporosis: A Path Forward

Khosla, S., Cauley, J. A., Compston, J., Kiel, D. P., Rosen, C., Saag, K. G. & Shane, E., Mar 1 2017, In : Journal of Bone and Mineral Research. 32, 3, p. 424-430 7 p.

Research output: Contribution to journalArticle

71 Scopus citations

A defect in renal calcium conservation may contribute to the pathogenesis of postmenopausal osteoporosis

Heshmati, H. M., Khosla, S., Burritt, M. F., O'fallon, W. M. & Riggs, B. L., Nov 11 1998, In : Journal of Clinical Endocrinology and Metabolism. 83, 6, p. 1916-1920 5 p.

Research output: Contribution to journalArticle

29 Scopus citations

A distal forearm fracture in childhood is associated with an increased risk for future fragility fractures in adult men, but not women

Amin, S., Melton, L. J., Achenbach, S. J., Atkinson, E. J., Dekutoski, M. B., Kirmani, S., Fischer, P. R. & Khosla, S., Aug 13 2013, In : Journal of Bone and Mineral Research. 28, 8, p. 1751-1759 9 p.

Research output: Contribution to journalArticle

25 Scopus citations

A DNA binding mutation in estrogen receptor-α Leads to suppression of Wnt signaling via β-catenin destabilization in osteoblasts

Mödder, U. I., Rudnik, V., Liu, G., Khosla, S. & Monroe, D. G., Jul 1 2012, In : Journal of cellular biochemistry. 113, 7, p. 2248-2255 8 p.

Research output: Contribution to journalArticle

11 Scopus citations

Adrenal crisis in the setting of high-dose ketoconazole therapy

Khosla, S., Wolfson, J. S., Demerjian, Z. & Godine, J. E., Jan 1 1989, In : Archives of internal medicine. 149, 4, p. 802-804 3 p.

Research output: Contribution to journalArticle

17 Scopus citations

Advancing the Science of Healthcare Service Delivery: The NHLBI Corporate Healthcare Leaders' Panel

Sampson, U. K. A., McGlynn, E. A., Perlin, J. B., Frisse, M. E., Arnold, S. B., Benz, E. J., Brennan, T., Briss, P., Beeuwkes Buntin, M. J., Khosla, S., King, R. G., Kuntz, R., Leider, H., Ling, S. M., Macrae, J., Murray, R., Thrailkill, E., Wager, C., Witchey, D. & Jacobson, H. R., Jan 1 2018, (Accepted/In press) In : Global Heart.

Research output: Contribution to journalArticle

A fragment of the hypophosphatemic factor, MEPE, requires inducible cyclooxygenase-2 to exert potent anabolic effects on normal human marrow osteoblast precursors

Nagel, D. E., Khosla, S., Sanyal, A., Rosen, D. M., Kumagai, Y. & Riggs, B. L., Dec 1 2004, In : Journal of cellular biochemistry. 93, 6, p. 1107-1114 8 p.

Research output: Contribution to journalArticle

15 Scopus citations

Age- and sex-specific differences in the factor of risk for vertebral fracture: A population-based study using QCT

Bouxsein, M. L., Melton, L. J., Riggs, B. L., Muller, J., Atkinson, E. J., Oberg, A. L., Robb, R. A., Camp, J. J., Rouleau, P. A., McCollough, C. H. & Khosla, S., Sep 1 2006, In : Journal of Bone and Mineral Research. 21, 9, p. 1475-1482 8 p.

Research output: Contribution to journalArticle

117 Scopus citations

Age-dependence of femoral strength in white women and men

Keaveny, T. M., Kopperdahl, D. L., Melton, L. J., Hoffmann, P. F., Amin, S., Riggs, B. L. & Khosla, S., May 1 2010, In : Journal of Bone and Mineral Research. 25, 5, p. 994-1001 8 p.

Research output: Contribution to journalArticle

114 Scopus citations

Age-dependent renal cortical microvascular loss in female mice

Urbieta-Caceres, V. H., Syed, F. A., Lin, J., Zhu, X. Y., Jordan, K. L., Bell, C. C., Bentley, M. D., Lerman, A., Khosla, S. & Lerman, L. O., Apr 15 2012, In : American Journal of Physiology - Endocrinology and Metabolism. 302, 8, p. E979-E986

Research output: Contribution to journalArticle

20 Scopus citations

Aging, Obesity, and the Incidence of Diverticulitis: A Population-Based Study

Lee, T. H., Setty, P. T., Parthasarathy, G., Bailey, K. R., Wood-Wentz, C. M., Fletcher, J. G., Takahashi, N. M., Khosla, S., Moynagh, M. R., Zinsmeister, A. R. & Bharucha, A. E., Sep 1 2018, In : Mayo Clinic Proceedings. 93, 9, p. 1256-1265 10 p.

Research output: Contribution to journalArticle

5 Scopus citations
1 Scopus citations

Androgens and bone

Clarke, B. L. & Khosla, S., Mar 1 2009, In : Steroids. 74, 3, p. 296-305 10 p.

Research output: Contribution to journalArticle

119 Scopus citations

A population-based assessment of rates of bone loss at multiple skeletal sites: Evidence for substantial trabecular bone loss in young adult women and men

Riggs, B. L., Melton, L. J., Robb, R. A., Camp, J. J., Atkinson, E. J., McDaniel, L., Amin, S., Rouleau, P. A. & Khosla, S., Feb 1 2008, In : Journal of Bone and Mineral Research. 23, 2, p. 205-214 10 p.

Research output: Contribution to journalArticle

337 Scopus citations

A potentially deleterious role of IGFBP-2 on bone density in aging men and women

Amin, S., Riggs, B. L., Atkinson, E. J., Oberg, A. L., Melton, L. J. & Khosla, S., Jul 1 2004, In : Journal of Bone and Mineral Research. 19, 7, p. 1075-1083 9 p.

Research output: Contribution to journalArticle

60 Scopus citations

Applications of a new handheld reference point indentation instrument measuring bone material strength

Randall, C., Bridges, D., Guerri, R., Nogues, X., Puig, L., Torres, E., Mellibovsky, L., Hoffseth, K., Stalbaum, T., Srikanth, A., Weaver, J. C., Rosen, S., Barnard, H., Brimer, D., Proctor, A., Candy, J., Saldana, C., Chandrasekar, S., Lescun, T., Nielson, C. M. & 9 others, Orwoll, E., Herthel, D., Kopeikin, H., Yang, H. T. Y., Farr, J. N., McCready, L., Khosla, S., Diez-Perez, A. & Hansma, P. K., Sep 24 2013, In : Journal of Medical Devices, Transactions of the ASME. 7, 4, 041005.

Research output: Contribution to journalArticle

39 Scopus citations

A randomised controlled trial of low-dose aspirin for the prevention of fractures in healthy older people: Protocol for the ASPREE-Fracture substudy

ASPREE Investigator Group, Aug 2016, In : Injury Prevention. 22, 4, p. 297-301 5 p.

Research output: Contribution to journalArticle

4 Scopus citations
6 Scopus citations

Aromatase inhibitor-associated bone fractures: A case-cohort GWAS and functional genomics

Liu, M., Goss, P. E., Ingle, J. N., Kubo, M., Furukawa, Y., Batzler, A., Jenkins, G. D., Carlson, E. E., Nakamura, Y., Schaid, D. J., Chapman, J. A. W., Shepherd, L. E., Ellis, M. J., Khosla, S., Wang, L. & Weinshilboum, R. M., Oct 1 2014, In : Molecular Endocrinology. 28, 10, p. 1740-1751 12 p.

Research output: Contribution to journalArticle

27 Scopus citations

Aspirin and fracture risk: A systematic review and exploratory meta-analysis of observational studies

Barker, A. L., Soh, S. E., Sanders, K. M., Pasco, J., Khosla, S., Ebeling, P. R., Ward, S. A., Peeters, G., Talevski, J., Cumming, R. G., Seeman, E. & McNeil, J. J., Feb 20 2020, In : BMJ open. 10, 2, 026876.

Research output: Contribution to journalArticle

Open Access

Assessing forearm fracture risk in postmenopausal women

Melton, L. J., Christen, D., Riggs, B. L., Achenbach, S. J., Müller, R., Van Lenthe, G. H., Amin, S., Atkinson, E. J. & Khosla, S., Jul 1 2010, In : Osteoporosis International. 21, 7, p. 1161-1169 9 p.

Research output: Contribution to journalArticle

87 Scopus citations

Assessing fracture risk using gradient boosting machine (GBM) models

Atkinson, E. J., Therneau, T. M., Melton, L. J., Camp, J. J., Achenbach, S. J., Amin, S. & Khosla, S., Jun 1 2012, In : Journal of Bone and Mineral Research. 27, 6, p. 1397-1404 8 p.

Research output: Contribution to journalArticle

27 Scopus citations

Assessment of gene regulation by bone morphogenetic protein 2 in human marrow stromal cells using gene array technology

Locklin, R. M., Riggs, B. L., Hicok, K. C., Horton, H. F., Byrne, M. C. & Khosla, S., Jan 1 2001, In : Journal of Bone and Mineral Research. 16, 12, p. 2192-2204 13 p.

Research output: Contribution to journalArticle

72 Scopus citations

Association of hip strength estimates by finite-element analysis with fractures in women and men

Amin, S., Kopperdhal, D. L., Melton, L. J., Achenbach, S. J., Therneau, T. M., Riggs, B. L., Keaveny, T. M. & Khosla, S., Jul 1 2011, In : Journal of Bone and Mineral Research. 26, 7, p. 1593-1600 8 p.

Research output: Contribution to journalArticle

74 Scopus citations
849 Scopus citations

Beta-lactamase inactivation by mechanism-based reagents.

Fisher, J., Belasco, J. G., Charnas, R. L., Khosla, S. & Knowles, J. R., May 16 1980, In : Philosophical transactions of the Royal Society of London. Series B, Biological sciences. 289, 1036, p. 309-319 11 p.

Research output: Contribution to journalArticle

Open Access
54 Scopus citations

Body composition during childhood and adolescence: Relations to bone strength and microstructure

Farr, J. N., Amin, S., LeBrasseur, N. K., Atkinson, E. J., Achenbach, S. J., McCready, L. K., Melton, L. J. & Khosla, S., Dec 1 2014, In : Journal of Clinical Endocrinology and Metabolism. 99, 12, p. 4641-4648 8 p.

Research output: Contribution to journalArticle

28 Scopus citations

Bone density and structure in healthy postmenopausal women treated with exemestane for the primary prevention of breast cancer: A nested substudy of the MAP.3 randomised controlled trial

Cheung, A. M., Tile, L., Cardew, S., Pruthi, S., Robbins, J., Tomlinson, G., Kapral, M. K., Khosla, S., Majumdar, S., Erlandson, M., Scher, J., Hu, H., Demaras, A., Lickley, L., Bordeleau, L., Elser, C., Ingle, J., Richardson, H. & Goss, P. E., Mar 1 2012, In : The Lancet Oncology. 13, 3, p. 275-284 10 p.

Research output: Contribution to journalArticle

73 Scopus citations

Bone growth and turnover in progesterone receptor knockout mice

Rickard, D. J., Iwaniec, U. T., Evans, G., Hefferan, T. E., Hunter, J. C., Waters, K. M., Lydon, J. P., O'Malley, B. W., Khosla, S., Spelsberg, T. C. & Turner, R. T., May 1 2008, In : Endocrinology. 149, 5, p. 2383-2390 8 p.

Research output: Contribution to journalArticle

28 Scopus citations

Bone marrow stromal cells express two distinct splice variants of ER-α that are regulated by estrogen

Sanyal, A., Riggs, B. L., Spelsberg, T. C. & Khosla, S., Jan 1 2005, In : Journal of cellular biochemistry. 94, 1, p. 88-97 10 p.

Research output: Contribution to journalArticle

10 Scopus citations

Bone microarchitecture in ankylosing spondylitis and the association with bone mineral density, fractures, and syndesmophytes

Klingberg, E., Lorentzon, M., Göthlin, J., Mellström, D., Geijer, M., Ohlsson, C., Atkinson, E. J., Khosla, S., Carlsten, H. & Forsblad-d'Elia, H., Nov 5 2013, In : Arthritis Research and Therapy. 15, 6, R179.

Research output: Contribution to journalArticle

47 Scopus citations

Bone microstructural changes revealed by high-resolution peripheral quantitative computed tomography imaging and elevated DKK1 and MIP-1α levels in patients with MGUS

Ng, A. C., Khosla, S., Charatcharoenwitthaya, N., Kumar, S. K., Achenbach, S. J., Holets, M. F., McCready, L. K., Melton, L. J., Kyle, R. A., Rajkumar, S. V. & Drake, M. T., Dec 15 2011, In : Blood. 118, 25, p. 6529-6534 6 p.

Research output: Contribution to journalArticle

46 Scopus citations

Bone strength and structural deficits in children and adolescents with a distal forearm fracture resulting from mild trauma

Farr, J. N., Amin, S., Melton, L. J., Kirmani, S., McCready, L. K., Atkinson, E. J., Müller, R. & Khosla, S., Mar 1 2014, In : Journal of Bone and Mineral Research. 29, 3, p. 590-599 10 p.

Research output: Contribution to journalArticle

46 Scopus citations

Bone structure at the distal radius during adolescent growth

Kirmani, S., Christen, D., Van Lenthe, G. H., Fischer, P. R., Bouxsein, M. L., McCready, L. K., Melton, L. J., Riggs, B. L., Amin, S., Müller, R. & Khosla, S., Jun 1 2009, In : Journal of Bone and Mineral Research. 24, 6, p. 1033-1042 10 p.

Research output: Contribution to journalArticle

181 Scopus citations

Bone turnover across the menopause transition: Correlations with inhibins and follicle-stimulating hormone

Perrien, D. S., Achenbach, S. J., Bledsoe, S. E., Walser, B., Suva, L. J., Khosla, S. & Gaddy, D., May 1 2006, In : Journal of Clinical Endocrinology and Metabolism. 91, 5, p. 1848-1854 7 p.

Research output: Contribution to journalArticle

83 Scopus citations

Calcium infusion suggests a “set-point” abnormality of parathyroid gland function in familial benign hypercalcemia and more complex disturbances in primary hyperparathyroidism

Khosla, S., Ebeling, P. R., Fireks, A. F., Burritt, M. M., Kao, P. C. & Heath, H., Mar 1993, In : Journal of Clinical Endocrinology and Metabolism. 76, 3, p. 715-720 6 p.

Research output: Contribution to journalArticle

142 Scopus citations

Canadian consensus practice guidelines for bisphosphonate associated osteonecrosis of the jaw

Khan, A. A., Sándor, G. K. B., Dore, E., Morrison, A. D., Alsahli, M., Amin, F., Peters, E., Hanley, D. A., Chaudry, S. R., Dempster, D. W., Glorieux, F. H., Neville, A. J., Talwar, R. M., Clokie, C. M., Al Mardini, M., Paul, T., Khosla, S., Josse, R. G., Sutherland, S., Lam, D. K. & 9 others, Carmichael, R. P., Blanas, N., Kendler, D., Petak, S., St.-Marie, L. G., Brown, J., Evans, A. W., Rios, L. & Compston, J. E., Jul 1 2008, In : Journal of Rheumatology. 35, 7, p. 1391-1397 7 p.

Research output: Contribution to journalArticle

152 Scopus citations

Can vitamin D metabolite measurements facilitate a “treat-to-target” paradigm to guide vitamin D supplementation?

Binkley, N., Lappe, J., Singh, R. J., Khosla, S., Krueger, D., Drezner, M. K. & Blank, R. D., May 1 2015, In : Osteoporosis International. 26, 5, p. 1655-1660 6 p.

Research output: Contribution to journalArticle

16 Scopus citations

Cellular senescence in bone

Farr, J. N. & Khosla, S., Apr 2019, In : Bone. 121, p. 121-133 13 p.

Research output: Contribution to journalArticle

15 Scopus citations

Changes in Runx2/Cbfa1 expression and activity during osteoblastic differentiation of human bone marrow stromal cells

Shui, C., Spelsberg, T. C., Riggs, B. L. & Khosla, S., Feb 1 2003, In : Journal of Bone and Mineral Research. 18, 2, p. 213-221 9 p.

Research output: Contribution to journalArticle

178 Scopus citations

Characterization of circulating osteoblast lineage cells in humans

Eghbali-Fatourechi, G. Z., Mödder, U. I. L., Charatcharoenwitthaya, N., Sanyal, A., Undale, A. H., Clowes, J. A., Tarara, J. E. & Khosla, S., May 2007, In : Bone. 40, 5, p. 1370-1377 8 p.

Research output: Contribution to journalArticle

113 Scopus citations

Characterization of mesenchymal progenitor cells isolated from human bone marrow by negative selection

Mödder, U. I., Roforth, M. M., Nicks, K. M., Peterson, J. M., McCready, L. K., Monroe, D. G. & Khosla, S., Mar 1 2012, In : Bone. 50, 3, p. 804-810 7 p.

Research output: Contribution to journalArticle

36 Scopus citations

Circulating cells with osteogenic potential

Khosla, S. & Eghbali-Fatourechi, G. Z., Apr 2006, In : Annals of the New York Academy of Sciences. 1068, 1, p. 489-497 9 p.

Research output: Contribution to journalArticle

69 Scopus citations