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Sundeep Khosla, MD

  • 39889 Citations
  • 101 Scopus h-Index
1976 …2021

Research output per year

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Research Output

{A figure is presented} Long-term fracture risk among women with proven endometriosis

Melton, L. J., Leibson, C. L., Good, A. E., Achenbach, S. J., Oberg, A. L. & Khosla, S., Dec 2006, In : Fertility and Sterility. 86, 6, p. 1576-1583 8 p.

Research output: Contribution to journal › Article

2 Scopus citations

Abdominal aortic calcification, BMD, and bone microstructure: A population-based study

Chow, J. T., Khosla, S., Melton, L. J., Atkinson, E. J., Camp, J. J. & Kearns, A. E., Oct 2008, In : Journal of Bone and Mineral Research. 23, 10, p. 1601-1612 12 p.

Research output: Contribution to journal › Article

33 Scopus citations

Ability of circulating human hematopoietic lineage negative cells to support hematopoiesis

Peris, P., Roforth, M. M., Nicks, K. M., Fraser, D., Fujita, K., Jilka, R. L., Khosla, S. & McGregor, U., Jan 1 2015, In : Journal of Cellular Biochemistry. 116, 1, p. 58-66 9 p.

Research output: Contribution to journal › Article

2 Scopus citations

Abnormalities of parathyroid hormone secretion in elderly women that are reversible by short term therapy with 1,25-dihydroxyvitamin D3

Ledger, G. A., Burritt, M. F., Kao, P. C., O'Fallon, W. M., Riggs, B. L. & Khosla, S., Jul 1994, In : Journal of Clinical Endocrinology and Metabolism. 79, 1, p. 211-216 6 p.

Research output: Contribution to journal › Article

72 Scopus citations

A bone structural basis for fracture risk in diabetes

Melton, L. J., Riggs, B. L., Leibson, C. L., Achenbach, S. J., Camp, J. J., Bouxsein, M. L., Atkinson, E. J., Robb, R. A. & Khosla, S., Dec 2008, In : Journal of Clinical Endocrinology and Metabolism. 93, 12, p. 4804-4809 6 p.

Research output: Contribution to journal › Article

107 Scopus citations

A Crisis in the Treatment of Osteoporosis

Khosla, S. & Shane, E., Aug 1 2016, In : Journal of Bone and Mineral Research. 31, 8, p. 1485-1487 3 p.

Research output: Contribution to journal › Editorial

123 Scopus citations

ACTH and indomethacin-induced antidiuresis in low salt Brattleboro strain rats: Induction and escape

Khosla, S., Kinter, L. B., Zusman, R. & Beeuwkes, R., 1982, In : Annals of the New York Academy of Sciences. Vol. 394, p. 265-269 5 p.

Research output: Contribution to journal › Article

Addressing the Crisis in the Treatment of Osteoporosis: A Path Forward

Khosla, S., Cauley, J. A., Compston, J., Kiel, D. P., Rosen, C., Saag, K. G. & Shane, E., Mar 1 2017, In : Journal of Bone and Mineral Research. 32, 3, p. 424-430 7 p.

Research output: Contribution to journal › Article

65 Scopus citations

A defect in renal calcium conservation may contribute to the pathogenesis of postmenopausal osteoporosis

Heshmati, H. M., Khosla, S., Burritt, M. F., O'fallon, W. M. & Riggs, B. L., 1998, In : Journal of Clinical Endocrinology and Metabolism. 83, 6, p. 1916-1920 5 p.

Research output: Contribution to journal › Article

29 Scopus citations

A distal forearm fracture in childhood is associated with an increased risk for future fragility fractures in adult men, but not women

Amin, S., Melton, L. J., Achenbach, S. J., Atkinson, E. J., Dekutoski, M. B., Kirmani, S., Fischer, P. R. & Khosla, S., 2013, In : Journal of Bone and Mineral Research. 28, 8, p. 1751-1759 9 p.

Research output: Contribution to journal › Article

24 Scopus citations

A DNA binding mutation in estrogen receptor-α Leads to suppression of Wnt signaling via β-catenin destabilization in osteoblasts

Mödder, U. I., Rudnik, V., Liu, G., Khosla, S. & Monroe, D. G., Jul 2012, In : Journal of Cellular Biochemistry. 113, 7, p. 2248-2255 8 p.

Research output: Contribution to journal › Article

11 Scopus citations

Adrenal crisis in the setting of high-dose ketoconazole therapy

Khosla, S., Wolfson, J. S., Demerjian, Z. & Godine, J. E., 1989, In : Archives of Internal Medicine. 149, 4, p. 802-804 3 p.

Research output: Contribution to journal › Article

17 Scopus citations

Advancing the Science of Healthcare Service Delivery: The NHLBI Corporate Healthcare Leaders' Panel

Sampson, U. K. A., McGlynn, E. A., Perlin, J. B., Frisse, M. E., Arnold, S. B., Benz, E. J., Brennan, T., Briss, P., Beeuwkes Buntin, M. J., Khosla, S., King, R. G., Kuntz, R., Leider, H., Ling, S. M., Macrae, J., Murray, R., Thrailkill, E., Wager, C., Witchey, D. & Jacobson, H. R., Jan 1 2018, (Accepted/In press) In : Global Heart.

Research output: Contribution to journal › Article

A fragment of the hypophosphatemic factor, MEPE, requires inducible cyclooxygenase-2 to exert potent anabolic effects on normal human marrow osteoblast precursors

Nagel, D. E., Khosla, S., Sanyal, A., Rosen, D. M., Kumagai, Y. & Riggs, B. L., 2004, In : Journal of Cellular Biochemistry. 93, 6, p. 1107-1114 8 p.

Research output: Contribution to journal › Article

15 Scopus citations

Age- and sex-specific differences in the factor of risk for vertebral fracture: A population-based study using QCT

Bouxsein, M. L., Melton, L. J., Riggs, B. L., Muller, J., Atkinson, E. J., Oberg, A. L., Robb, R. A., Camp, J. J., Rouleau, P. A., McCollough, C. H. & Khosla, S., Sep 2006, In : Journal of Bone and Mineral Research. 21, 9, p. 1475-1482 8 p.

Research output: Contribution to journal › Article

113 Scopus citations

Age-dependence of femoral strength in white women and men

Keaveny, T. M., Kopperdahl, D. L., Melton, L. J., Hoffmann, P. F., Amin, S., Riggs, B. L. & Khosla, S., May 2010, In : Journal of Bone and Mineral Research. 25, 5, p. 994-1001 8 p.

Research output: Contribution to journal › Article

109 Scopus citations

Age-dependent renal cortical microvascular loss in female mice

Urbieta-Caceres, V. H., Syed, F. A., Lin, J., Zhu, X. Y., Jordan, K. L., Bell, C. C., Bentley, M. D., Lerman, A., Khosla, S. & Lerman, L. O., Apr 15 2012, In : American Journal of Physiology - Endocrinology and Metabolism. 302, 8

Research output: Contribution to journal › Article

20 Scopus citations

Aging, Obesity, and the Incidence of Diverticulitis: A Population-Based Study

Lee, T. H., Setty, P. T., Parthasarathy, G., Bailey, K. R., Wood-Wentz, C. M., Fletcher, J. G., Takahashi, N. M., Khosla, S., Moynagh, M. R., Zinsmeister, A. R. & Bharucha, A. E., Sep 1 2018, In : Mayo Clinic Proceedings. 93, 9, p. 1256-1265 10 p.

Research output: Contribution to journal › Article

4 Scopus citations

A Lot of Progress, With More to Be Done: A Response to NIH Pathways to Prevention Report “Research Gaps for Long-Term Drug Therapies for Osteoporotic Fracture Prevention”

Leder, B. Z., Clarke, B., Shane, E., Khosla, S. & Kiel, D. P., Jan 1 2019, (Accepted/In press) In : Journal of Bone and Mineral Research.

Research output: Contribution to journal › Article

1 Scopus citations

Androgen effects on bone metabolism: Recent progress and controversies

Hofbauer, L. C. & Khosla, S., Apr 1999, In : European Journal of Endocrinology. 140, 4, p. 271-286 16 p.

Research output: Contribution to journal › Article

115 Scopus citations

Androgens, estrogens, and bone turnover in men (multiple letters)

Khosla, S., Riggs, B. L., Leder, B. Z. & Finkelstein, J. S., May 1 2003, In : Journal of Clinical Endocrinology and Metabolism. 88, 5, p. 2352-2353 2 p.

Research output: Contribution to journal › Article

11 Scopus citations

Androgens and bone

Clarke, B. & Khosla, S., Mar 2009, In : Steroids. 74, 3, p. 296-305 10 p.

Research output: Contribution to journal › Article

115 Scopus citations

A population-based assessment of rates of bone loss at multiple skeletal sites: Evidence for substantial trabecular bone loss in young adult women and men

Riggs, B. L., Melton, L. J., Robb, R. A., Camp, J. J., Atkinson, E. J., McDaniel, L., Amin, S., Rouleau, P. A. & Khosla, S., Feb 2008, In : Journal of Bone and Mineral Research. 23, 2, p. 205-214 10 p.

Research output: Contribution to journal › Article

329 Scopus citations

A potentially deleterious role of IGFBP-2 on bone density in aging men and women

Amin, S., Riggs, B. L., Atkinson, E. J., Oberg, A. L., Melton, L. J. & Khosla, S., Jul 2004, In : Journal of Bone and Mineral Research. 19, 7, p. 1075-1083 9 p.

Research output: Contribution to journal › Article

60 Scopus citations

Applications of a new handheld reference point indentation instrument measuring bone material strength

Randall, C., Bridges, D., Guerri, R., Nogues, X., Puig, L., Torres, E., Mellibovsky, L., Hoffseth, K., Stalbaum, T., Srikanth, A., Weaver, J. C., Rosen, S., Barnard, H., Brimer, D., Proctor, A., Candy, J., Saldana, C., Chandrasekar, S., Lescun, T., Nielson, C. M. & 9 others, Orwoll, E., Herthel, D., Kopeikin, H., Yang, H. T. Y., Farr, J., McCready, L., Khosla, S., Diez-Perez, A. & Hansma, P. K., Sep 24 2013, In : Journal of Medical Devices, Transactions of the ASME. 7, 4, 041005.

Research output: Contribution to journal › Article

38 Scopus citations

A randomised controlled trial of low-dose aspirin for the prevention of fractures in healthy older people: Protocol for the ASPREE-Fracture substudy

ASPREE Investigator Group, May 21 2015, (Accepted/In press) In : Injury Prevention.

Research output: Contribution to journal › Article

4 Scopus citations

A randomized placebo-controlled trial of short-term graded transdermal estradiol in healthy gonadotropin-releasing hormone agonist-suppressed pre- and postmenopausal women: Effects on serum markers of bone turnover, insulin-like growth factor-I, and osteoclastogenic mediators

Liu, P. Y., Hoey, K. A., Mielke, K. L., Veldhuis, J. D. & Khosla, S., Apr 2005, In : Journal of Clinical Endocrinology and Metabolism. 90, 4, p. 1953-1960 8 p.

Research output: Contribution to journal › Article

6 Scopus citations

Are the endocrine society's clinical practice guidelines on androgen therapy in women misguided? A commentary-response

Wierman, M., Basson, R., Davis, S., Khosla, S., Miller, K., Rosner, W. & Santoro, N., Nov 2007, In : Journal of Sexual Medicine. 4, 6, p. 1782-1783 2 p.

Research output: Contribution to journal › Article

6 Scopus citations

Aromatase inhibitor-associated bone fractures: A case-cohort GWAS and functional genomics

Liu, M., Goss, P. E., Ingle, J. N., Kubo, M., Furukawa, Y., Batzler, A., Jenkins, G. D., Carlson, E. E., Nakamura, Y., Schaid, D. J., Chapman, J. A. W., Shepherd, L. E., Ellis, M. J., Khosla, S., Wang, L. M. & Weinshilboum, R. M., Oct 1 2014, In : Molecular Endocrinology. 28, 10, p. 1740-1751 12 p.

Research output: Contribution to journal › Article

26 Scopus citations

Assessing forearm fracture risk in postmenopausal women

Melton, L. J., Christen, D., Riggs, B. L., Achenbach, S. J., Müller, R., Van Lenthe, G. H., Amin, S., Atkinson, E. J. & Khosla, S., Jul 2010, In : Osteoporosis International. 21, 7, p. 1161-1169 9 p.

Research output: Contribution to journal › Article

85 Scopus citations

Assessing fracture risk using gradient boosting machine (GBM) models

Atkinson, E. J., Therneau, T. M., Melton, L. J., Camp, J. J., Achenbach, S. J., Amin, S. & Khosla, S., Jun 2012, In : Journal of Bone and Mineral Research. 27, 6, p. 1397-1404 8 p.

Research output: Contribution to journal › Article

25 Scopus citations

Assessing the true impact of recurrent fractures on fracture risk

Clarke, B. & Khosla, S., 2009, In : Journal of Bone and Mineral Research. 24, 9, p. 1512-1514 3 p.

Research output: Contribution to journal › Article

1 Scopus citations

Assessment of gene regulation by bone morphogenetic protein 2 in human marrow stromal cells using gene array technology

Locklin, R. M., Riggs, B. L., Hicok, K. C., Horton, H. F., Byrne, M. C. & Khosla, S., 2001, In : Journal of Bone and Mineral Research. 16, 12, p. 2192-2204 13 p.

Research output: Contribution to journal › Article

71 Scopus citations

Association of hip strength estimates by finite-element analysis with fractures in women and men

Amin, S., Kopperdhal, D. L., Melton, L. J., Achenbach, S. J., Therneau, T. M., Riggs, B. L., Keaveny, T. M. & Khosla, S., Jul 2011, In : Journal of Bone and Mineral Research. 26, 7, p. 1593-1600 8 p.

Research output: Contribution to journal › Article

70 Scopus citations

A system for the analysis of whole-bone strength from helical CT images

Camp, J. J., Karwoski, R. A., Stacy, M. C., Atkinson, E. J., Khosla, S., Melton, L. J., Riggs, B. L. & Robb, R. A., 2004, Proceedings of SPIE - The International Society for Optical Engineering. Amini, A. A. & Mandura, A. (eds.). Vol. 5369. p. 74-88 15 p.

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

27 Scopus citations

A unitary model for involutional osteoporosis: Estrogen deficiency causes both type I and type II osteoporosis in postmenopausal women and contributes to bone loss in aging men

Riggs, B. L., Khosla, S. & Melton, L. J., May 1998, In : Journal of Bone and Mineral Research. 13, 5, p. 763-773 11 p.

Research output: Contribution to journal › Article

844 Scopus citations

Autoimmune hemolytic anemia with both cold and warm autoantibodies.

Nusbaum, N. J. & Khosla, S., Sep 6 1985, In : Journal of the American Medical Association. 254, 9, p. 1175-1176 2 p.

Research output: Contribution to journal › Article

6 Scopus citations

Benefits and risks of bisphosphonate therapy for osteoporosis: Editorial comment

Khosla, S., Bilezikian, J. P., Dempster, D. W., Lewiecki, E. M., Miller, P. D., Neer, R. M., Recker, R. R., Shane, E., Shoback, D. & Potts, J. T., Jan 2013, In : Obstetrical and Gynecological Survey. 68, 1, p. 37-39 3 p.

Research output: Contribution to journal › Article

Benefits and risks of bisphosphonate therapy for osteoporosis

Khosla, S., Bilezikian, J. P., Dempster, D. W., Lewiecki, E. M., Miller, P. D., Neer, R. M., Recker, R. R., Shane, E., Shoback, D. & Potts, J. T., Jul 2012, In : Journal of Clinical Endocrinology and Metabolism. 97, 7, p. 2272-2282 11 p.

Research output: Contribution to journal › Article

151 Scopus citations

Beta-lactamase inactivation by mechanism-based reagents.

Fisher, J., Belasco, J. G., Charnas, R. L., Khosla, S. & Knowles, J. R., May 16 1980, In : Philosophical transactions of the Royal Society of London. Series B: Biological sciences. 289, 1036, p. 309-319 11 p.

Research output: Contribution to journal › Article

52 Scopus citations

Better tools for assessing osteoporosis

Riggs, B. L., Khosla, S. & Melton, L. J., Dec 3 2012, In : Journal of Clinical Investigation. 122, 12, p. 4323-4324 2 p.

Research output: Contribution to journal › Article

10 Scopus citations

Bisphosphonate associated osteonecrosis of the jaw

Khan, A. A., Sándor, G. K. B., Dore, E., Morrison, A. D., Alsahli, M., Amin, F., Peters, E., Hanley, D. A., Chaudry, S. R., Lentle, B., Dempster, D. W., Glorieux, F. H., Neville, A. J., Talwar, R. M., Clokie, C. M., Al Mardini, M., Paul, T., Khosla, S., Josse, R. G., Sutherland, S. & 10 others, Lam, D. K., Carmichael, R. P., Blanas, N., Kendler, D., Petak, S., Ste-Marie, L. G., Brown, J., Evans, A. W., Rios, L. & Compston, J. E., Mar 2009, In : Journal of Rheumatology. 36, 3, p. 478-490 13 p.

Research output: Contribution to journal › Article

122 Scopus citations

Bisphosphonate-associated osteonecrosis of the jaw: Report of a Task Force of the American Society for Bone and Mineral Research

Khosla, S., Burr, D., Cauley, J., Dempster, D. W., Ebeling, P. R., Felsenberg, D., Gagel, R. F., Gilsanz, V., Guise, T., Koka, S., McCauley, L. K., McGowan, J., McKee, M. D., Mohla, S., Pendrys, D. G., Raisz, L. G., Ruggiero, S. L., Shafer, D. M., Shum, L., Silverman, S. L. & 4 others, Van Poznak, C. H., Watts, N., Woo, S. B. & Shane, E., Oct 2007, In : Journal of Bone and Mineral Research. 22, 10, p. 1479-1491 13 p.

Research output: Contribution to journal › Article

1176 Scopus citations

Bisphosphonates: Mechanism of action and role in clinical practice

Drake, M. M., Clarke, B. & Khosla, S., 2008, In : Mayo Clinic Proceedings. 83, 9, p. 1032-1045 14 p.

Research output: Contribution to journal › Article

622 Scopus citations

Bisphosphonates and the upper gastrointestinal tract: Skeletal gain without visceral pain?

Tremaine, W. J. & Khosla, S., Oct 1 2002, In : Mayo Clinic Proceedings. 77, 10, p. 1029-1030 2 p.

Research output: Contribution to journal › Article

5 Scopus citations

Body composition during childhood and adolescence: Relations to bone strength and microstructure

Farr, J., Amin, S., LeBrasseur, N. K., Atkinson, E. J., Achenbach, S. J., McCready, L. K., Melton, L. J. & Khosla, S., Dec 1 2014, In : Journal of Clinical Endocrinology and Metabolism. 99, 12, p. 4641-4648 8 p.

Research output: Contribution to journal › Article

24 Scopus citations

Bone density and structure in healthy postmenopausal women treated with exemestane for the primary prevention of breast cancer: A nested substudy of the MAP.3 randomised controlled trial

Cheung, A. M., Tile, L., Cardew, S., Pruthi, S., Robbins, J., Tomlinson, G., Kapral, M. K., Khosla, S., Majumdar, S., Erlandson, M., Scher, J., Hu, H., Demaras, A., Lickley, L., Bordeleau, L., Elser, C., Ingle, J., Richardson, H. & Goss, P. E., Mar 2012, In : The Lancet Oncology. 13, 3, p. 275-284 10 p.

Research output: Contribution to journal › Article

72 Scopus citations

Bone diseases: Romosozumab-on track or derailed?

Khosla, S., Dec 1 2017, In : Nature Reviews Endocrinology. 13, 12, p. 697-698 2 p.

Research output: Contribution to journal › Short survey

11 Scopus citations

Bone fragility in men - Where are we?

Seeman, E., Bianchi, G., Khosla, S., Kanis, J. A. & Orwoll, E., Nov 2006, In : Osteoporosis International. 17, 11, p. 1577-1583 7 p.

Research output: Contribution to journal › Article

76 Scopus citations

Bone growth and turnover in progesterone receptor knockout mice

Rickard, D. J., Iwaniec, U. T., Evans, G., Hefferan, T. E., Hunter, J. C., Waters, K. M., Lydon, J. P., O'Malley, B. W., Khosla, S., Spelsberg, T. C. & Turner, R. T., May 2008, In : Endocrinology. 149, 5, p. 2383-2390 8 p.

Research output: Contribution to journal › Article

24 Scopus citations