• 39889 Citations
  • 101 Scopus h-Index
1976 …2021

Research output per year

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Research Output

1999

The assembly of the adult skeleton during growth and maturation: Implications for senile osteoporosis

Riggs, B. L., Khosla, S. & Melton, L. J., 1999, In : Journal of Clinical Investigation. 104, 6, p. 671-672 2 p.

Research output: Contribution to journalArticle

39 Scopus citations
1998

A defect in renal calcium conservation may contribute to the pathogenesis of postmenopausal osteoporosis

Heshmati, H. M., Khosla, S., Burritt, M. F., O'fallon, W. M. & Riggs, B. L., 1998, In : Journal of Clinical Endocrinology and Metabolism. 83, 6, p. 1916-1920 5 p.

Research output: Contribution to journalArticle

29 Scopus citations
844 Scopus citations

Effects of gonadal and adrenal androgens in a novel androgen-responsive human osteoblastic cell line

Hofbauer, L. C., Hicok, K. C. & Khosla, S., Oct 1 1998, In : Journal of Cellular Biochemistry. 71, 1, p. 96-108 13 p.

Research output: Contribution to journalArticle

36 Scopus citations

Effects of the circadian variation in serum cortisol on markers of bone turnover and calcium homeostasis in normal postmenopausal women

Heshmati, H. M., Riggs, B. L., Burritt, M. F., Mcalister, C. A., Wollan, P. C. & Khosla, S., 1998, In : Journal of Clinical Endocrinology and Metabolism. 83, 3, p. 751-756 6 p.

Research output: Contribution to journalArticle

68 Scopus citations

Fracture risk among patients with urolithiasis: A population-based cohort study

Melton, L. J., Crowson, C., Khosla, S., Wilson, D. M. & O'Fallon, W. M., 1998, In : Kidney International. 53, 2, p. 459-464 6 p.

Research output: Contribution to journalArticle

113 Scopus citations

Idiopathic osteoporosis: Is the osteoblast to blame? [4] (multiple letters)

Parfitt, A. M., Weinstein, R. S. & Khosla, S., 1998, In : Journal of Clinical Endocrinology and Metabolism. 83, 2, p. 716 1 p.

Research output: Contribution to journalArticle

1 Scopus citations

Idiopathic osteoporosis: A heterogeneous entity

Heshmati, H. M. & Khosla, S., Mar 1998, In : Annales de Medecine Interne. 149, 2, p. 77-81 5 p.

Research output: Contribution to journalArticle

16 Scopus citations

Insulin-like growth factor system abnormalities in hepatitis C- associated osteosclerosis. Potential insights into increasing bone mass in adults

Khosla, S., Hassoun, A. A. K., Baker, B. K., Liu, F., Zein, N. N., Whyte, M. P., Reasner, C. A., Nippoldt, T. B., Tiegs, R. D., Hintz, R. L. & Conover, C. A., May 15 1998, In : Journal of Clinical Investigation. 101, 10, p. 2165-2173 9 p.

Research output: Contribution to journalArticle

81 Scopus citations

Interaction between estrogen and vitamin D-endocrine system: A potential addition to the unitary model of osteoporosis

Liel, Y., Shany, S., Schwartz, B., Lawrence Riggs, B., Khosla, S. & Joseph Melton, L., 1998, In : Journal of Bone and Mineral Research. 13, 12, p. 1954-1955 2 p.

Research output: Contribution to journalArticle

3 Scopus citations

Osteoprotegerin production by human osteoblast lineage cells is stimulated by vitamin D, bone morphogenetic protein-2, and cytokines

Hofbauer, L. C., Dunstan, C. R., Spelsberg, T. C., Riggs, B. L. & Khosla, S., Sep 29 1998, In : Biochemical and Biophysical Research Communications. 250, 3, p. 776-781 6 p.

Research output: Contribution to journalArticle

260 Scopus citations

Relationship of serum sex steroid levels and bone turnover markers with bone mineral density in men and women: A key role for bioavailable estrogen

Khosla, S., Melton, L. J., Atkinson, E. J., O'Fallon, W. M., Klee, G. G. & Riggs, B. L., 1998, In : Journal of Clinical Endocrinology and Metabolism. 83, 7, p. 2266-2274 9 p.

Research output: Contribution to journalArticle

801 Scopus citations

Survival after the diagnosis of hyperparathyroidism: A population-based study

Wermers, R. A., Khosla, S., Atkinson, E. J., Grant, C. S., Hodgson, S. F., O'Fallon, W. M. & Melton, L. J., Feb 1998, In : American Journal of Medicine. 104, 2, p. 115-122 8 p.

Research output: Contribution to journalArticle

214 Scopus citations
1997

Development and characterization of a conditionally immortalized human osteoblastic cell line stably transfected with the human androgen receptor gene

Hofbauer, L. C., Hicok, K. C., Schroeder, M. J., Harris, S. A., Robinson, J. A. & Khosla, S., Sep 15 1997, In : Journal of Cellular Biochemistry. 66, 4, p. 542-551 10 p.

Research output: Contribution to journalArticle

13 Scopus citations

Editorial: Idiopathic osteoporosis - Is the osteoblast to blame?

Khosla, S., 1997, In : Journal of Clinical Endocrinology and Metabolism. 82, 9, p. 2792-2794 3 p.

Research output: Contribution to journalArticle

28 Scopus citations

Effects of age and estrogen status on serum parathyroid hormone levels and biochemical markers of bone turnover in women: A population-based study

Khosla, S., Atkinson, E. J., Melton, L. J. & Riggs, B. L., 1997, In : Journal of Clinical Endocrinology and Metabolism. 82, 5, p. 1522-1527 6 p.

Research output: Contribution to journalArticle

202 Scopus citations

Genetic testing in medullary thyroid carcinoma syndromes: Mutation types and clinical significance

Heshmati, H. M., Gharib, H., Khosla, S., Abu-Lebdeh, H. S., Lindor, N. M. & Thibodeau, S. N., 1997, In : Mayo Clinic Proceedings. 72, 5, p. 430-436 7 p.

Research output: Contribution to journalArticle

38 Scopus citations

Hepatitis C-associated osteosclerosis: An unusual syndrome of acquired osteosclerosis in adults

Hassoun, A. A. K., Nippoldt, T. B., Tiegs, R. D. & Khosla, S., Jul 1997, In : American Journal of Medicine. 103, 1, p. 70-73 4 p.

Research output: Contribution to journalArticle

23 Scopus citations

Is familial hyperparathyroidism a unique disease?

Barry, M. K., Van Heerden, J. A., Grant, C. S., Thompson, G. B. & Khosla, S., Dec 1997, In : Surgery. 122, 6, p. 1028-1033 6 p.

Research output: Contribution to journalArticle

26 Scopus citations

Relationship of bone turnover to bone density and fractures

Melton, L. J., Khosla, S., Atkinson, E. J., O'Fallon, W. M. & Riggs, B. L., Jul 1997, In : Journal of Bone and Mineral Research. 12, 7, p. 1083-1091 9 p.

Research output: Contribution to journalArticle

310 Scopus citations

Role of estrogen deficiency in pathogenesis of secondary hyperparathyroidism and increased bone resorption in elderly women

McKane, W. R., Khosla, S., Risteli, J., Robins, S. P., Muhs, J. M. & Riggs, B. L., 1997, In : Proceedings of the Association of American Physicians. 109, 2, p. 174-180 7 p.

Research output: Contribution to journalArticle

40 Scopus citations

The rise and fall of primary hyperparathyroidism: A population-based study in Rochester, Minnesota, 1965-1992

Wermers, R. A., Khosla, S., Atkinson, E. J., Hodgson, S. F., O'Fallon, W. M. & Melton, L. J., 1997, In : Annals of Internal Medicine. 126, 6, p. 433-440 8 p.

Research output: Contribution to journalArticle

238 Scopus citations

Update on primary osteoporosis

Hurley, D. L. & Khosla, S., 1997, In : Mayo Clinic Proceedings. 72, 10, p. 943-949 7 p.

Research output: Contribution to journalArticle

14 Scopus citations
1996

Cytokine production in the bone marrow microenvironment: Failure to demonstrate estrogen regulation in early postmenopausal women

Kassem, M., Khosla, S., Spelsberg, T. C. & Riggs, B. L., 1996, In : Journal of Clinical Endocrinology and Metabolism. 81, 2, p. 513-518 6 p.

Research output: Contribution to journalArticle

58 Scopus citations

Non-suppressible parathyroid hormone secretion is related to gland size in uremic secondary hyperparathyroidism

Indridason, O. S., Heath, H., Khosla, S., Yohay, D. A. & Quarles, L. D., Nov 1996, In : Kidney International. 50, 5, p. 1663-1671 9 p.

Research output: Contribution to journalArticle

58 Scopus citations

Relationship between body composition and bone mass in women

Khosla, S., Atkinson, E. J., Riggs, B. L. & Melton, L. J., Jun 1996, In : Journal of Bone and Mineral Research. 11, 6, p. 857-863 7 p.

Research output: Contribution to journalArticle

257 Scopus citations

Role of calcium intake in modulating age-related increases in parathyroid function and bone resorption

Mckane, W. R., Khosla, S., Egan, K. S., Robins, S. P., Burritt, M. F. & Riggs, B. L., 1996, In : Journal of Clinical Endocrinology and Metabolism. 81, 5, p. 1699-1703 5 p.

Research output: Contribution to journalArticle

175 Scopus citations
1995

Familial medullary thyroid cancer and prominent corneal nerves: Clinical and genetic analysis

Kane, L. A., Tsai, M. S., Gharib, H., Khosla, S., Robertson, D. M., Schaid, D. J., Honchel, R. & Thibodeau, S. N., 1995, In : Journal of Clinical Endocrinology and Metabolism. 80, 1, p. 289-293 5 p.

Research output: Contribution to journalArticle

16 Scopus citations

Genetic testing in the diagnosis and management of multiple endocrine neoplasia type II

Ledger, G. A., Khosla, S., Lindor, N. M., Thibodeau, S. N. & Gharib, H., 1995, In : Annals of Internal Medicine. 122, 2, p. 118-124 7 p.

Research output: Contribution to journalArticle

84 Scopus citations

Mechanism of renal calcium conservation with estrogen replacement therapy in women in early postmenopause - A clinical research center study

McKane, W. R., Khosla, S., Burritt, M. F., Kao, P. C., Wilson, D. M., Ory, S. J. & Riggs, B. L., 1995, In : Journal of Clinical Endocrinology and Metabolism. 80, 12, p. 3458-3464 7 p.

Research output: Contribution to journalArticle

103 Scopus citations

Mutations in the RET protooncogene in sporadic pheochromocytomas

Lindor, N. M., Honchel, R., Khosla, S. & Thibodeau, S. N., 1995, In : Journal of Clinical Endocrinology and Metabolism. 80, 2, p. 627-629 3 p.

Research output: Contribution to journalArticle

61 Scopus citations

Role of biochemical markers in assessment of osteoporosis.

Riggs, B. L. & Khosla, S., Oct 1995, In : Acta orthopaedica Scandinavica. Supplementum. 266, p. 14-18 5 p.

Research output: Contribution to journalArticle

7 Scopus citations

Role of parathyroid hormone in mediating nocturnal and age-related increases in bone resorption

Ledger, G. A., Burritt, M. F., Kao, P. C., O'Fallon, W. M., Riggs, B. L. & Khosla, S., 1995, In : Journal of Clinical Endocrinology and Metabolism. 80, 11, p. 3304-3310 7 p.

Research output: Contribution to journalArticle

123 Scopus citations

Treatment options for osteoporosis.

Khosla, S. & Riggs, B. L., Oct 1995, In : Mayo Clinic Proceedings. 70, 10, p. 978-982 5 p.

Research output: Contribution to journalArticle

16 Scopus citations
1994

Abnormalities of parathyroid hormone secretion in elderly women that are reversible by short term therapy with 1,25-dihydroxyvitamin D3

Ledger, G. A., Burritt, M. F., Kao, P. C., O'Fallon, W. M., Riggs, B. L. & Khosla, S., Jul 1994, In : Journal of Clinical Endocrinology and Metabolism. 79, 1, p. 211-216 6 p.

Research output: Contribution to journalArticle

72 Scopus citations

Circulating cytokine levels in osteoporotic and normal women

Khosla, S., Peterson, J. M., Egan, K., Jones, J. D. & Riggs, B. L., 1994, In : Journal of Clinical Endocrinology and Metabolism. 79, 3, p. 707-711 5 p.

Research output: Contribution to journalArticle

Circulating cytokine levels in osteoporotic and normal women

Khosla, S., Peterson, J. M., Egan, K., Jones, J. D. & Riggs, B. L., Sep 1994, In : Journal of Clinical Endocrinology and Metabolism. 79, 3, p. 707-711 5 p.

Research output: Contribution to journalArticle

83 Scopus citations

Circulating levels of cytokines that modulate bone resorption: Effects of age and menopause in women

McKane, W. R., Khosla, S., Peterson, J. M., Egan, K. & Riggs, B. L., Aug 1994, In : Journal of Bone and Mineral Research. 9, 8, p. 1313-1318 6 p.

Research output: Contribution to journalArticle

86 Scopus citations

Epidemiology and clinical features of osteoporosis in young individuals

Khosla, S., Lufkin, E. G., Hodgson, S. F., Fitzpatrick, L. A. & Melton, L. J., 1994, In : Bone. 15, 5, p. 551-555 5 p.

Research output: Contribution to journalArticle

132 Scopus citations

Identification of multiple endocrine neoplasia, type 2 gene carriers using linkage analysis and analysis of the RET proto-oncogene

Tsai, M. S., Ledger, G. A., Khosla, S., Gharib, H. & Thibodeau, S. N., May 1994, In : Journal of Clinical Endocrinology and Metabolism. 78, 5, p. 1261-1264 4 p.

Research output: Contribution to journalArticle

47 Scopus citations
25 Scopus citations
1993

Calcium infusion suggests a "set-point" abnormality of parathyroid gland function in familial benign hypercalcemia and more complex disturbances in primary hyperparathyroidism

Khosla, S., Ebeling, P. R., Firek, A. F., Burritt, M. M., Kao, P. C. & Heath, H., Mar 1993, In : Journal of Clinical Endocrinology and Metabolism. 76, 3, p. 715-720 6 p.

Research output: Contribution to journalArticle

141 Scopus citations

Expression of a potential metastasis suppressor gene (nm23) in thyroid neoplasms

Farley, D. R., Eberhardt, N. L., Grant, C. S., Schaid, D. J., Van Heerden, J. A., Hay, I. D., Khosla, S. & Backdahl, M., 1993, In : World Journal of Surgery. 17, 5, p. 615-621 7 p.

Research output: Contribution to journalArticle

13 Scopus citations

Muscle strength in Osteoporotic versus normal women

Sinaki, M., Khosla, S., Limburg, P. J., Rogers, J. W. & Murtaugh, P. A., Jan 1993, In : Osteoporosis International. 3, 1, p. 8-12 5 p.

Research output: Contribution to journalArticle

72 Scopus citations
1992

Clinical performance of parathyroid hormone immunometric assays

Kao, P. C., Van Heerden, J. A., Grant, C. S., Klee, G. G. & Khosla, S., 1992, In : Mayo Clinic Proceedings. 67, 7, p. 637-645 9 p.

Research output: Contribution to journalArticle

70 Scopus citations

In vitro and in vivo detection of somatostatin receptors in pheochromocytomas and paragangliomas

Reubi, J. C., Waser, B., Khosla, S., Kvols, L., Goellner, J. R., Krenning, E. & Lamberts, S., May 1992, In : Journal of Clinical Endocrinology and Metabolism. 74, 5, p. 1082-1089 8 p.

Research output: Contribution to journalArticle

84 Scopus citations
1991

Loss of heterozygosity suggests multiple Genetic alterations in pheochromocytomas and medullary thyroid carcinomas

Khosla, S., Patel, V. M., Hay, I. D., Schaid, D. J., Grant, C. S., Van Heerden, J. A. & Thibodeau, S. N., May 1991, In : Journal of Clinical Investigation. 87, 5, p. 1691-1699 9 p.

Research output: Contribution to journalArticle

108 Scopus citations
1990

Parathyroid hormone-related peptide in lactation and in umbilical cord blood

Khosla, S., Johansen, K. L., Ory, S. J., O'Brien, P. C. & Kao, P. C., 1990, In : Mayo Clinic Proceedings. 65, 11, p. 1408-1414 7 p.

Research output: Contribution to journalArticle

53 Scopus citations

Parathyroid hormone-related protein and hypercalcemia secondary to massive mammary hyperplasia

Khosla, S., Van Heerden, J. A., Gharib, H., Jackson, I. T., Danks, J., Hayman, J. A. & Martin, T. J., 1990, In : New England Journal of Medicine. 322, 16, p. 1157 1 p.

Research output: Contribution to journalArticle

94 Scopus citations
1989

Adrenal crisis in the setting of high-dose ketoconazole therapy

Khosla, S., Wolfson, J. S., Demerjian, Z. & Godine, J. E., 1989, In : Archives of Internal Medicine. 149, 4, p. 802-804 3 p.

Research output: Contribution to journalArticle

17 Scopus citations