• 38865 Citations
  • 100 Scopus h-Index
1976 …2021
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Research Output 1980 2019

1998
35 Citations (Scopus)

Effects of gonadal and adrenal androgens in a novel androgen-responsive human osteoblastic cell line

Hofbauer, L. C., Hicok, K. C. & Khosla, S., Oct 1 1998, In : Journal of Cellular Biochemistry. 71, 1, p. 96-108 13 p.

Research output: Contribution to journalArticle

Androgen Receptors
Androgens
Cells
Cell Line
Dihydrotestosterone
67 Citations (Scopus)

Effects of the circadian variation in serum cortisol on markers of bone turnover and calcium homeostasis in normal postmenopausal women

Heshmati, H. M., Riggs, B. L., Burritt, M. F., Mcalister, C. A., Wollan, P. C. & Khosla, S., 1998, In : Journal of Clinical Endocrinology and Metabolism. 83, 3, p. 751-756 6 p.

Research output: Contribution to journalArticle

Bone Remodeling
Hydrocortisone
Bone
Homeostasis
Calcium
110 Citations (Scopus)

Fracture risk among patients with urolithiasis: A population-based cohort study

Melton, L. J., Crowson, C., Khosla, S., Wilson, D. M. & O'Fallon, W. M., 1998, In : Kidney International. 53, 2, p. 459-464 6 p.

Research output: Contribution to journalArticle

Urolithiasis
Cohort Studies
Population
Adrenal Cortex Hormones
Confidence Intervals
1 Citation (Scopus)

Idiopathic osteoporosis: Is the osteoblast to blame? [4] (multiple letters)

Parfitt, A. M., Weinstein, R. S. & Khosla, S., 1998, In : Journal of Clinical Endocrinology and Metabolism. 83, 2, p. 716 1 p.

Research output: Contribution to journalArticle

Osteoblasts
Osteoporosis
15 Citations (Scopus)

Idiopathic osteoporosis: A heterogeneous entity

Heshmati, H. M. & Khosla, S., Mar 1998, In : Annales de Medecine Interne. 149, 2, p. 77-81 5 p.

Research output: Contribution to journalArticle

Osteoporosis
Colles' Fracture
Hypercalciuria
Compression Fractures
Bone and Bones
80 Citations (Scopus)

Insulin-like growth factor system abnormalities in hepatitis C- associated osteosclerosis. Potential insights into increasing bone mass in adults

Khosla, S., Hassoun, A. A. K., Baker, B. K., Liu, F., Zein, N. N., Whyte, M. P., Reasner, C. A., Nippoldt, T. B., Tiegs, R. D., Hintz, R. L. & Conover, C. A., May 15 1998, In : Journal of Clinical Investigation. 101, 10, p. 2165-2173 9 p.

Research output: Contribution to journalArticle

Osteosclerosis
Insulin-Like Growth Factor II
Somatomedins
Hepatitis C
Insulin-Like Growth Factor Binding Protein 2
4 Citations (Scopus)

Interaction between estrogen and vitamin D-endocrine system: A potential addition to the unitary model of osteoporosis

Liel, Y., Shany, S., Schwartz, B., Lawrence Riggs, B., Khosla, S. & Joseph Melton, L., 1998, In : Journal of Bone and Mineral Research. 13, 12, p. 1954-1955 2 p.

Research output: Contribution to journalArticle

Biological Models
Calcitriol Receptors
Endocrine System
Intestinal Mucosa
Vitamin D
258 Citations (Scopus)

Osteoprotegerin production by human osteoblast lineage cells is stimulated by vitamin D, bone morphogenetic protein-2, and cytokines

Hofbauer, L. C., Dunstan, C. R., Spelsberg, T. C., Riggs, B. L. & Khosla, S., Sep 29 1998, In : Biochemical and Biophysical Research Communications. 250, 3, p. 776-781 6 p.

Research output: Contribution to journalArticle

Osteoprotegerin
Bone Morphogenetic Protein 2
Osteoblasts
Vitamin D
Cytokines
790 Citations (Scopus)

Relationship of serum sex steroid levels and bone turnover markers with bone mineral density in men and women: A key role for bioavailable estrogen

Khosla, S., Melton, L. J., Atkinson, E. J., O'Fallon, W. M., Klee, G. G. & Riggs, B. L., 1998, In : Journal of Clinical Endocrinology and Metabolism. 83, 7, p. 2266-2274 9 p.

Research output: Contribution to journalArticle

Bone Remodeling
Bone Density
Minerals
Bone
Estrogens
213 Citations (Scopus)

Survival after the diagnosis of hyperparathyroidism: A population-based study

Wermers, R. A., Khosla, S., Atkinson, E. J., Grant, C. S., Hodgson, S. F., O'Fallon, W. M. & Melton, L. J., Feb 1998, In : American Journal of Medicine. 104, 2, p. 115-122 8 p.

Research output: Contribution to journalArticle

Hyperparathyroidism
Survival
Primary Hyperparathyroidism
Population
Hyperthyroidism
1997
13 Citations (Scopus)

Development and characterization of a conditionally immortalized human osteoblastic cell line stably transfected with the human androgen receptor gene

Hofbauer, L. C., Hicok, K. C., Schroeder, M. J., Harris, S. A., Robinson, J. A. & Khosla, S., Sep 15 1997, In : Journal of Cellular Biochemistry. 66, 4, p. 542-551 10 p.

Research output: Contribution to journalArticle

Androgen Receptors
Genes
Cells
Cell Line
Androgens
28 Citations (Scopus)

Editorial: Idiopathic osteoporosis - Is the osteoblast to blame?

Khosla, S., 1997, In : Journal of Clinical Endocrinology and Metabolism. 82, 9, p. 2792-2794 3 p.

Research output: Contribution to journalArticle

Bone Remodeling
Osteoblasts
Somatomedins
Osteoporosis
200 Citations (Scopus)

Effects of age and estrogen status on serum parathyroid hormone levels and biochemical markers of bone turnover in women: A population-based study

Khosla, S., Atkinson, E. J., Melton, L. J. & Riggs, B. L., 1997, In : Journal of Clinical Endocrinology and Metabolism. 82, 5, p. 1522-1527 6 p.

Research output: Contribution to journalArticle

Bone Remodeling
Parathyroid Hormone
Bone
Estrogens
Biomarkers
38 Citations (Scopus)

Genetic testing in medullary thyroid carcinoma syndromes: Mutation types and clinical significance

Heshmati, H. M., Gharib, H., Khosla, S., Abu-Lebdeh, H. S., Lindor, N. M. & Thibodeau, S. N., 1997, In : Mayo Clinic Proceedings. 72, 5, p. 430-436 7 p.

Research output: Contribution to journalArticle

Multiple Endocrine Neoplasia
Genetic Testing
Codon
Mutation
Germ-Line Mutation
23 Citations (Scopus)

Hepatitis C-associated osteosclerosis: An unusual syndrome of acquired osteosclerosis in adults

Hassoun, A. A. K., Nippoldt, T. B., Tiegs, R. D. & Khosla, S., Jul 1997, In : American Journal of Medicine. 103, 1, p. 70-73 4 p.

Research output: Contribution to journalArticle

Osteosclerosis
Hepatitis C
26 Citations (Scopus)

Is familial hyperparathyroidism a unique disease?

Barry, M. K., Van Heerden, J. A., Grant, C. S., Thompson, G. B. & Khosla, S., Dec 1997, In : Surgery. 122, 6, p. 1028-1033 6 p.

Research output: Contribution to journalArticle

Hyperparathyroidism
Nephrolithiasis
Parathyroid Diseases
Multiple Endocrine Neoplasia
Thymectomy
309 Citations (Scopus)

Relationship of bone turnover to bone density and fractures

Melton, L. J., Khosla, S., Atkinson, E. J., O'Fallon, W. M. & Riggs, B. L., Jul 1997, In : Journal of Bone and Mineral Research. 12, 7, p. 1083-1091 9 p.

Research output: Contribution to journalArticle

Bone Remodeling
Bone Fractures
Bone Density
Osteoporotic Fractures
Osteocalcin
39 Citations (Scopus)

Role of estrogen deficiency in pathogenesis of secondary hyperparathyroidism and increased bone resorption in elderly women

McKane, W. R., Khosla, S., Risteli, J., Robins, S. P., Muhs, J. M. & Riggs, B. L., 1997, In : Proceedings of the Association of American Physicians. 109, 2, p. 174-180 7 p.

Research output: Contribution to journalArticle

Secondary Hyperparathyroidism
Bone Resorption
Estrogens
Urine
Parathyroid Hormone
234 Citations (Scopus)

The rise and fall of primary hyperparathyroidism: A population-based study in Rochester, Minnesota, 1965-1992

Wermers, R. A., Khosla, S., Atkinson, E. J., Hodgson, S. F., O'Fallon, W. M. & Melton, L. J., 1997, In : Annals of Internal Medicine. 126, 6, p. 433-440 8 p.

Research output: Contribution to journalArticle

Primary Hyperparathyroidism
Incidence
Population
Hyperparathyroidism
Hypercalcemia
14 Citations (Scopus)

Update on primary osteoporosis

Hurley, D. L. & Khosla, S., 1997, In : Mayo Clinic Proceedings. 72, 10, p. 943-949 7 p.

Research output: Contribution to journalArticle

Osteoporosis
Life Expectancy
Population
Delivery of Health Care
Bone and Bones
1996
58 Citations (Scopus)

Cytokine production in the bone marrow microenvironment: Failure to demonstrate estrogen regulation in early postmenopausal women

Kassem, M., Khosla, S., Spelsberg, T. C. & Riggs, B. L., 1996, In : Journal of Clinical Endocrinology and Metabolism. 81, 2, p. 513-518 6 p.

Research output: Contribution to journalArticle

Bone
Estrogens
Bone Marrow
Cytokines
Interleukin-1
57 Citations (Scopus)

Non-suppressible parathyroid hormone secretion is related to gland size in uremic secondary hyperparathyroidism

Indridason, O. S., Heath, H., Khosla, S., Yohay, D. A. & Quarles, L. D., Nov 1996, In : Kidney International. 50, 5, p. 1663-1671 9 p.

Research output: Contribution to journalArticle

Secondary Hyperparathyroidism
Parathyroid Hormone
Calcium
Parathyroid Glands
Primary Hyperparathyroidism
255 Citations (Scopus)

Relationship between body composition and bone mass in women

Khosla, S., Atkinson, E. J., Riggs, B. L. & Melton, L. J., Jun 1996, In : Journal of Bone and Mineral Research. 11, 6, p. 857-863 7 p.

Research output: Contribution to journalArticle

Body Composition
Bone Density
Bone and Bones
Fat Body
Pelvic Bones
174 Citations (Scopus)

Role of calcium intake in modulating age-related increases in parathyroid function and bone resorption

Mckane, W. R., Khosla, S., Egan, K. S., Robins, S. P., Burritt, M. F. & Riggs, B. L., 1996, In : Journal of Clinical Endocrinology and Metabolism. 81, 5, p. 1699-1703 5 p.

Research output: Contribution to journalArticle

Bone Resorption
Bone
Calcium
Parathyroid Hormone
Parathyroid Glands
1995
16 Citations (Scopus)

Familial medullary thyroid cancer and prominent corneal nerves: Clinical and genetic analysis

Kane, L. A., Tsai, M. S., Gharib, H., Khosla, S., Robertson, D. M., Schaid, D. J., Honchel, R. & Thibodeau, S. N., 1995, In : Journal of Clinical Endocrinology and Metabolism. 80, 1, p. 289-293 5 p.

Research output: Contribution to journalArticle

Multiple Endocrine Neoplasia
DNA sequences
Exons
Pentagastrin
Calcitonin
84 Citations (Scopus)

Genetic testing in the diagnosis and management of multiple endocrine neoplasia type II

Ledger, G. A., Khosla, S., Lindor, N. M., Thibodeau, S. N. & Gharib, H., 1995, In : Annals of Internal Medicine. 122, 2, p. 118-124 7 p.

Research output: Contribution to journalArticle

Multiple Endocrine Neoplasia
Genetic Testing
Pentagastrin
Information Storage and Retrieval
Calcitonin
103 Citations (Scopus)

Mechanism of renal calcium conservation with estrogen replacement therapy in women in early postmenopause - A clinical research center study

McKane, W. R., Khosla, S., Burritt, M. F., Kao, P. C., Wilson, D. M., Ory, S. J. & Riggs, B. L., 1995, In : Journal of Clinical Endocrinology and Metabolism. 80, 12, p. 3458-3464 7 p.

Research output: Contribution to journalArticle

Postmenopause
Estrogen Replacement Therapy
Conservation
Estrogens
Calcium
61 Citations (Scopus)

Mutations in the RET protooncogene in sporadic pheochromocytomas

Lindor, N. M., Honchel, R., Khosla, S. & Thibodeau, S. N., 1995, In : Journal of Clinical Endocrinology and Metabolism. 80, 2, p. 627-629 3 p.

Research output: Contribution to journalArticle

Pheochromocytoma
Exons
Mutation
Tumors
Multiple Endocrine Neoplasia
7 Citations (Scopus)

Role of biochemical markers in assessment of osteoporosis.

Riggs, B. L. & Khosla, S., Oct 1995, In : Acta orthopaedica Scandinavica. Supplementum. 266, p. 14-18 5 p.

Research output: Contribution to journalArticle

Postmenopausal Osteoporosis
Osteocalcin
Diphosphonates
Bone Density
Osteoporosis
122 Citations (Scopus)

Role of parathyroid hormone in mediating nocturnal and age-related increases in bone resorption

Ledger, G. A., Burritt, M. F., Kao, P. C., O'Fallon, W. M., Riggs, B. L. & Khosla, S., 1995, In : Journal of Clinical Endocrinology and Metabolism. 80, 11, p. 3304-3310 7 p.

Research output: Contribution to journalArticle

Bone Resorption
Parathyroid Hormone
Bone
Calcium
Serum
16 Citations (Scopus)

Treatment options for osteoporosis.

Khosla, S. & Riggs, B. L., Oct 1995, In : Mayo Clinic Proceedings. 70, 10, p. 978-982 5 p.

Research output: Contribution to journalArticle

Osteoporosis
Estradiol Congeners
Postmenopausal Osteoporosis
Estrogen Replacement Therapy
Diphosphonates
1994
71 Citations (Scopus)

Abnormalities of parathyroid hormone secretion in elderly women that are reversible by short term therapy with 1,25-dihydroxyvitamin D3

Ledger, G. A., Burritt, M. F., Kao, P. C., O'Fallon, W. M., Riggs, B. L. & Khosla, S., Jul 1994, In : Journal of Clinical Endocrinology and Metabolism. 79, 1, p. 211-216 6 p.

Research output: Contribution to journalArticle

Calcitriol
Parathyroid Hormone
Aging of materials
Edetic Acid
Bone

Circulating cytokine levels in osteoporotic and normal women

Khosla, S., Peterson, J. M., Egan, K., Jones, J. D. & Riggs, B. L., 1994, In : Journal of Clinical Endocrinology and Metabolism. 79, 3, p. 707-711 5 p.

Research output: Contribution to journalArticle

Interleukin-1
Interleukin-1 Receptors
Cytokines
Bone
Interleukin-6
83 Citations (Scopus)

Circulating cytokine levels in osteoporotic and normal women

Khosla, S., Peterson, J. M., Egan, K., Jones, J. D. & Riggs, B. L., Sep 1994, In : Journal of Clinical Endocrinology and Metabolism. 79, 3, p. 707-711 5 p.

Research output: Contribution to journalArticle

Interleukin-1
Interleukin-1 Receptors
Cytokines
Bone
Interleukin-6
86 Citations (Scopus)

Circulating levels of cytokines that modulate bone resorption: Effects of age and menopause in women

McKane, W. R., Khosla, S., Peterson, J. M., Egan, K. & Riggs, B. L., Aug 1994, In : Journal of Bone and Mineral Research. 9, 8, p. 1313-1318 6 p.

Research output: Contribution to journalArticle

Bone Resorption
Menopause
Interleukin-1
Cytokines
Interleukin-1 Receptors
131 Citations (Scopus)

Epidemiology and clinical features of osteoporosis in young individuals

Khosla, S., Lufkin, E. G., Hodgson, S. F., Fitzpatrick, L. A. & Melton, L. J., 1994, In : Bone. 15, 5, p. 551-555 5 p.

Research output: Contribution to journalArticle

Osteoporosis
Epidemiology
Osteoblasts
Incidence
Delayed Puberty
47 Citations (Scopus)

Identification of multiple endocrine neoplasia, type 2 gene carriers using linkage analysis and analysis of the RET proto-oncogene

Tsai, M. S., Ledger, G. A., Khosla, S., Gharib, H. & Thibodeau, S. N., May 1994, In : Journal of Clinical Endocrinology and Metabolism. 78, 5, p. 1261-1264 4 p.

Research output: Contribution to journalArticle

Multiple Endocrine Neoplasia Type 2a
Proto-Oncogenes
Genes
Exons
DNA sequences
25 Citations (Scopus)
Transforming Growth Factors
RNA
Cell Line
Growth
Messenger RNA
1993
141 Citations (Scopus)

Calcium infusion suggests a "set-point" abnormality of parathyroid gland function in familial benign hypercalcemia and more complex disturbances in primary hyperparathyroidism

Khosla, S., Ebeling, P. R., Firek, A. F., Burritt, M. M., Kao, P. C. & Heath, H., Mar 1993, In : Journal of Clinical Endocrinology and Metabolism. 76, 3, p. 715-720 6 p.

Research output: Contribution to journalArticle

Parathyroid Glands
Primary Hyperparathyroidism
Calcium
Tumors
Plasmas
13 Citations (Scopus)

Expression of a potential metastasis suppressor gene (nm23) in thyroid neoplasms

Farley, D. R., Eberhardt, N. L., Grant, C. S., Schaid, D. J., Van Heerden, J. A., Hay, I. D., Khosla, S. & Backdahl, M., 1993, In : World Journal of Surgery. 17, 5, p. 615-621 7 p.

Research output: Contribution to journalArticle

Follicular Adenocarcinoma
Lymphatic Metastasis
Medullary Carcinoma
Papillary Carcinoma
Tumor Suppressor Genes
72 Citations (Scopus)

Muscle strength in Osteoporotic versus normal women

Sinaki, M., Khosla, S., Limburg, P. J., Rogers, J. W. & Murtaugh, P. A., Jan 1993, In : Osteoporosis International. 3, 1, p. 8-12 5 p.

Research output: Contribution to journalArticle

Muscle Strength
Osteoporosis
Exercise
Back Pain
Posture
1992
69 Citations (Scopus)

Clinical performance of parathyroid hormone immunometric assays

Kao, P. C., Van Heerden, J. A., Grant, C. S., Klee, G. G. & Khosla, S., 1992, In : Mayo Clinic Proceedings. 67, 7, p. 637-645 9 p.

Research output: Contribution to journalArticle

Parathyroid Hormone
Immunoradiometric Assay
Primary Hyperparathyroidism
Hypercalcemia
Radioimmunoassay
84 Citations (Scopus)

In vitro and in vivo detection of somatostatin receptors in pheochromocytomas and paragangliomas

Reubi, J. C., Waser, B., Khosla, S., Kvols, L., Goellner, J. R., Krenning, E. & Lamberts, S., May 1992, In : Journal of Clinical Endocrinology and Metabolism. 74, 5, p. 1082-1089 8 p.

Research output: Contribution to journalArticle

Paraganglioma
Somatostatin Receptors
Pheochromocytoma
Tumors
Loss of Heterozygosity
1991
108 Citations (Scopus)

Loss of heterozygosity suggests multiple Genetic alterations in pheochromocytomas and medullary thyroid carcinomas

Khosla, S., Patel, V. M., Hay, I. D., Schaid, D. J., Grant, C. S., Van Heerden, J. A. & Thibodeau, S. N., May 1991, In : Journal of Clinical Investigation. 87, 5, p. 1691-1699 9 p.

Research output: Contribution to journalArticle

Loss of Heterozygosity
Pheochromocytoma
Multiple Endocrine Neoplasia Type 2a
Genetic Loci
Chromosomes
1990
53 Citations (Scopus)

Parathyroid hormone-related peptide in lactation and in umbilical cord blood

Khosla, S., Johansen, K. L., Ory, S. J., O'Brien, P. C. & Kao, P. C., 1990, In : Mayo Clinic Proceedings. 65, 11, p. 1408-1414 7 p.

Research output: Contribution to journalArticle

Parathyroid Hormone-Related Protein
Fetal Blood
Lactation
Human Milk
Hyperprolactinemia
94 Citations (Scopus)

Parathyroid hormone-related protein and hypercalcemia secondary to massive mammary hyperplasia

Khosla, S., Van Heerden, J. A., Gharib, H., Jackson, I. T., Danks, J., Hayman, J. A. & Martin, T. J., 1990, In : New England Journal of Medicine. 322, 16, p. 1157 1 p.

Research output: Contribution to journalArticle

Parathyroid Hormone-Related Protein
Pregnancy Complications
Hypercalcemia
Hyperplasia
Breast
1989
17 Citations (Scopus)

Adrenal crisis in the setting of high-dose ketoconazole therapy

Khosla, S., Wolfson, J. S., Demerjian, Z. & Godine, J. E., 1989, In : Archives of Internal Medicine. 149, 4, p. 802-804 3 p.

Research output: Contribution to journalArticle

Ketoconazole
Adrenal Insufficiency
Hypothyroidism
Acanthamoeba Keratitis
Therapeutics
1988
39 Citations (Scopus)

Nucleotide sequence of cloned cDNAs encoding chicken preproparathyroid hormone

Khosla, S., Demay, M., Pines, M., Hurwitz, S., Potts, J. T. & Kronenberg, H. M., 1988, In : Journal of Bone and Mineral Research. 3, 6, p. 689-698 10 p.

Research output: Contribution to journalArticle

Chickens
Complementary DNA
Hormones
Nucleotides
Amino Acids
1985
6 Citations (Scopus)

Autoimmune hemolytic anemia with both cold and warm autoantibodies.

Nusbaum, N. J. & Khosla, S., Sep 6 1985, In : Journal of the American Medical Association. 254, 9, p. 1175-1176 2 p.

Research output: Contribution to journalArticle

Autoimmune Hemolytic Anemia
Agglutinins
Autoantibodies
Temperature
1982

ACTH and indomethacin-induced antidiuresis in low salt Brattleboro strain rats: Induction and escape

Khosla, S., Kinter, L. B., Zusman, R. & Beeuwkes, R., 1982, In : Annals of the New York Academy of Sciences. Vol. 394, p. 265-269 5 p.

Research output: Contribution to journalArticle

Brattleboro Rats
Vasopressins
Indomethacin
Adrenocorticotropic Hormone
Rats