• 39889 Citations
  • 101 Scopus h-Index
1976 …2021

Research output per year

If you made any changes in Pure these will be visible here soon.

Research Output

2010

Physiology of Bone Loss

Clarke, B. & Khosla, S., May 2010, In : Radiologic Clinics of North America. 48, 3, p. 483-495 13 p.

Research output: Contribution to journalArticle

127 Scopus citations

Placebo-controlled fracture trials in osteoporosis - Comment on the article by Stein and Ray

Rosen, C. J. & Khosla, S., Sep 30 2010, In : New England Journal of Medicine. 363, 14

Research output: Contribution to journalArticle

1 Scopus citations

Placebo-controlled trials in osteoporosis - Proceeding with caution

Rosen, C. J. & Khosla, S., Sep 30 2010, In : New England Journal of Medicine. 363, 14, p. 1365-1367 3 p.

Research output: Contribution to journalArticle

16 Scopus citations

Relation of serum serotonin levels to bone density and structural parameters in women

Mödder, U. I., Achenbach, S. J., Amin, S., Riggs, B. L., Melton, L. J. & Khosla, S., Feb 2010, In : Journal of Bone and Mineral Research. 25, 2, p. 415-422 8 p.

Research output: Contribution to journalArticle

65 Scopus citations

Relation of vertebral deformities to bone density, structure, and strength

Melton, L. J., Riggs, B. L., Keaveny, T. M., Achenbach, S. J., Kopperdahl, D., Camp, J. J., Rouleau, P. A., Amin, S., Atkinson, E. J., Robb, R. A., Therneau, T. M. & Khosla, S., Sep 2010, In : Journal of Bone and Mineral Research. 25, 9, p. 1922-1930 9 p.

Research output: Contribution to journalArticle

65 Scopus citations

The endogenous selective estrogen receptor modulator 27-hydroxycholesterol is a negative regulator of bone homeostasis

DuSell, C. D., Nelson, E. R., Wang, X., Abdo, J., Mödder, U. I., Umetani, M., Gesty-Palmer, D., Javitt, N. B., Khosla, S. & McDonnell, D. P., Aug 2010, In : Endocrinology. 151, 8, p. 3675-3685 11 p.

Research output: Contribution to journalArticle

61 Scopus citations

Update in male osteoporosis

Khosla, S., Jan 2010, In : Journal of Clinical Endocrinology and Metabolism. 95, 1, p. 3-10 8 p.

Research output: Contribution to journalArticle

119 Scopus citations

Update on estrogens and the skeleton

Khosla, S., Aug 2010, In : Journal of Clinical Endocrinology and Metabolism. 95, 8, p. 3569-3577 9 p.

Research output: Contribution to journalArticle

113 Scopus citations
2009

Androgens and bone

Clarke, B. & Khosla, S., Mar 2009, In : Steroids. 74, 3, p. 296-305 10 p.

Research output: Contribution to journalArticle

115 Scopus citations

Assessing the true impact of recurrent fractures on fracture risk

Clarke, B. & Khosla, S., 2009, In : Journal of Bone and Mineral Research. 24, 9, p. 1512-1514 3 p.

Research output: Contribution to journalArticle

1 Scopus citations

Bisphosphonate associated osteonecrosis of the jaw

Khan, A. A., Sándor, G. K. B., Dore, E., Morrison, A. D., Alsahli, M., Amin, F., Peters, E., Hanley, D. A., Chaudry, S. R., Lentle, B., Dempster, D. W., Glorieux, F. H., Neville, A. J., Talwar, R. M., Clokie, C. M., Al Mardini, M., Paul, T., Khosla, S., Josse, R. G., Sutherland, S. & 10 others, Lam, D. K., Carmichael, R. P., Blanas, N., Kendler, D., Petak, S., Ste-Marie, L. G., Brown, J., Evans, A. W., Rios, L. & Compston, J. E., Mar 2009, In : Journal of Rheumatology. 36, 3, p. 478-490 13 p.

Research output: Contribution to journalArticle

122 Scopus citations

Bone structure at the distal radius during adolescent growth

Kirmani, S., Christen, D., Van Lenthe, G. H., Fischer, P. R., Bouxsein, M. L., McCready, L. K., Melton, L. J., Riggs, B. L., Amin, S., Müller, R. & Khosla, S., Jun 2009, In : Journal of Bone and Mineral Research. 24, 6, p. 1033-1042 10 p.

Research output: Contribution to journalArticle

177 Scopus citations

Estrogen action on bone marrow osteoclast lineage cells of postmenopausal women in vivo

Clowes, J. A., Eghbali-Fatourechi, G. Z., McCready, L., Oursler, M. J., Khosla, S. & Riggs, B. L., May 2009, In : Osteoporosis International. 20, 5, p. 761-769 9 p.

Research output: Contribution to journalArticle

15 Scopus citations

Fatty acid metabolism in the elderly: Effects of dehydroepiandrosterone and testosterone replacement in hormonally deficient men and women

Koutsari, C., Ali, A. H., Nair, K. S., Rizza, R. A., O'Brien, P., Khosla, S. & Jensen, M. D., Sep 2009, In : Journal of Clinical Endocrinology and Metabolism. 94, 9, p. 3414-3423 10 p.

Research output: Contribution to journalArticle

20 Scopus citations
71 Scopus citations

Higher muscle protein synthesis in women than men across the lifespan, and failure of androgen administration to amend age-related decrements

Henderson, G. C., Dhatariya, K., Ford, G. C., Klaus, K. A., Basu, R., Rizza, R. A., Jensen, M. D., Khosla, S., O'Brien, P. & Nair, K. S., Feb 2009, In : FASEB Journal. 23, 2, p. 631-641 11 p.

Research output: Contribution to journalArticle

62 Scopus citations

Increasing options for the treatment of osteoporosis

Khosla, S., Aug 20 2009, In : New England Journal of Medicine. 361, 8, p. 818-820 3 p.

Research output: Contribution to journalArticle

57 Scopus citations

Mesenchymal stem cells for bone repair and metabolic bone diseases

Undale, A. H., Westendorf, J. J., Yaszemski, M. J. & Khosla, S., 2009, In : Mayo Clinic Proceedings. 84, 10, p. 893-902 10 p.

Research output: Contribution to journalArticle

130 Scopus citations

New selective estrogen and androgen receptor modulators

Clarke, B. & Khosla, S., Jul 2009, In : Current Opinion in Rheumatology. 21, 4, p. 374-379 6 p.

Research output: Contribution to journalArticle

28 Scopus citations

Role of Sex Steroids in the Pathogenesis of Osteoporosis

Drake, M. M. & Khosla, S., Dec 23 2009, Primer on the Metabolic Bone Diseases and Disorders of Mineral Metabolism: Seventh Edition. John Wiley & Sons, Inc., p. 208-213 6 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

4 Scopus citations

Skeletal consequences of deletion of steroid receptor coactivator-2/transcription intermediary factor-2

Mödder, U. I., Monroe, D. G., Fraser, D. G., Spelsberg, T. C., Rosen, C. J., Géhin, M., Chambon, P., O'Malley, B. W. & Khosla, S., Jul 10 2009, In : Journal of Biological Chemistry. 284, 28, p. 18767-18777 11 p.

Research output: Contribution to journalArticle

22 Scopus citations

Targeting bone remodeling for the treatment of osteoporosis: summary of the proceedings of an ASBMR workshop

Bilezikian, J. P., Matsumoto, T., Bellido, T., Khosla, S., Martin, J., Recker, R. R., Heaney, R., Seeman, E., Papapoulos, S. & Goldring, S. R., Mar 2009, In : Journal of Bone and Mineral Research. 24, 3, p. 373-385 13 p.

Research output: Contribution to journalArticle

42 Scopus citations

Testosterone: More is not always better

Khosla, S., Dec 2009, In : Journal of Clinical Endocrinology and Metabolism. 94, 12, p. 4665-4667 3 p.

Research output: Contribution to journalArticle

3 Scopus citations
2008

Abdominal aortic calcification, BMD, and bone microstructure: A population-based study

Chow, J. T., Khosla, S., Melton, L. J., Atkinson, E. J., Camp, J. J. & Kearns, A. E., Oct 2008, In : Journal of Bone and Mineral Research. 23, 10, p. 1601-1612 12 p.

Research output: Contribution to journalArticle

33 Scopus citations

A bone structural basis for fracture risk in diabetes

Melton, L. J., Riggs, B. L., Leibson, C. L., Achenbach, S. J., Camp, J. J., Bouxsein, M. L., Atkinson, E. J., Robb, R. A. & Khosla, S., Dec 2008, In : Journal of Clinical Endocrinology and Metabolism. 93, 12, p. 4804-4809 6 p.

Research output: Contribution to journalArticle

107 Scopus citations

A population-based assessment of rates of bone loss at multiple skeletal sites: Evidence for substantial trabecular bone loss in young adult women and men

Riggs, B. L., Melton, L. J., Robb, R. A., Camp, J. J., Atkinson, E. J., McDaniel, L., Amin, S., Rouleau, P. A. & Khosla, S., Feb 2008, In : Journal of Bone and Mineral Research. 23, 2, p. 205-214 10 p.

Research output: Contribution to journalArticle

329 Scopus citations

Bisphosphonates: Mechanism of action and role in clinical practice

Drake, M. M., Clarke, B. & Khosla, S., 2008, In : Mayo Clinic Proceedings. 83, 9, p. 1032-1045 14 p.

Research output: Contribution to journalArticle

622 Scopus citations

Bone growth and turnover in progesterone receptor knockout mice

Rickard, D. J., Iwaniec, U. T., Evans, G., Hefferan, T. E., Hunter, J. C., Waters, K. M., Lydon, J. P., O'Malley, B. W., Khosla, S., Spelsberg, T. C. & Turner, R. T., May 2008, In : Endocrinology. 149, 5, p. 2383-2390 8 p.

Research output: Contribution to journalArticle

24 Scopus citations

Bone-targeted replacement therapy for hypophosphatasia

Drake, M. M. & Khosla, S., Jun 2008, In : Journal of Bone and Mineral Research. 23, 6, p. 775-776 2 p.

Research output: Contribution to journalArticle

5 Scopus citations

Building bone to reverse osteoporosis and repair fractures

Khosla, S., Westendorf, J. J. & Oursler, M. J., Feb 1 2008, In : Journal of Clinical Investigation. 118, 2, p. 421-428 8 p.

Research output: Contribution to journalArticle

273 Scopus citations

Canadian consensus practice guidelines for bisphosphonate associated osteonecrosis of the jaw

Khan, A. A., Sándor, G. K. B., Dore, E., Morrison, A. D., Alsahli, M., Amin, F., Peters, E., Hanley, D. A., Chaudry, S. R., Dempster, D. W., Glorieux, F. H., Neville, A. J., Talwar, R. M., Clokie, C. M., Al Mardini, M., Paul, T., Khosla, S., Josse, R. G., Sutherland, S., Lam, D. K. & 9 others, Carmichael, R. P., Blanas, N., Kendler, D., Petak, S., St.-Marie, L. G., Brown, J., Evans, A. W., Rios, L. & Compston, J. E., Jul 2008, In : Journal of Rheumatology. 35, 7, p. 1391-1397 7 p.

Research output: Contribution to journalArticle

150 Scopus citations
56 Scopus citations

Cost-effective osteoporosis treatment thresholds: The United States perspective

Tosteson, A. N. A., Melton, L. J., Dawson-Hughes, B., Bairn, S., Favus, M. J., Khosla, S. & Lindsay, R. L., Aug 2008, In : Obstetrical and Gynecological Survey. 63, 8, p. 516-517 2 p.

Research output: Contribution to journalArticle

Cost-effective osteoporosis treatment thresholds: The United States perspective

Tosteson, A. N. A., Melton, L. J., Dawson-Hughes, B., Baim, S., Favus, M. J., Khosla, S. & Lindsay, R. L., Apr 2008, In : Osteoporosis International. 19, 4, p. 437-447 11 p.

Research output: Contribution to journalArticle

320 Scopus citations

Effects of estrogen therapy on bone marrow adipocytes in postmenopausal osteoporotic women

Syed, F. A., Oursler, M. J., Hefferanm, T. E., Peterson, J. M., Riggs, B. L. & Khosla, S., Sep 2008, In : Osteoporosis International. 19, 9, p. 1323-1330 8 p.

Research output: Contribution to journalArticle

117 Scopus citations

Estrogen, Bone Homeostasis, and Osteoporosis

Riggs, B. L., Khosla, S. & Melton, L. J., 2008, Osteoporosis, Two-Volume Set. Elsevier Inc., p. 1011-1039 29 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

8 Scopus citations

Estrogen and bone: Insights from estrogen-resistant, aromatase-deficient, and normal men

Khosla, S., Sep 2008, In : Bone. 43, 3, p. 414-417 4 p.

Research output: Contribution to journalArticle

36 Scopus citations

Estrogen and fracture risk in men

Gennari, L., Khosla, S. & Bilezikian, J. P., Oct 2008, In : Journal of Bone and Mineral Research. 23, 10, p. 1548-1551 4 p.

Research output: Contribution to journalArticle

27 Scopus citations

Estrogen Effects on Bone in the Male Skeleton

Gennari, L., Khosla, S. & Bilezikian, J. P., 2008, Principles of Bone Biology, Two-Volume Set. Elsevier Inc., Vol. 2. p. 1801-1818 18 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

3 Scopus citations
37 Scopus citations

Fracture risk in type 2 diabetes: Update of a population-based study

Melton, L. J., Leibson, C. L., Achenbach, S. J., Therneau, T. M. & Khosla, S., Aug 2008, In : Journal of Bone and Mineral Research. 23, 8, p. 1334-1342 9 p.

Research output: Contribution to journalArticle

226 Scopus citations

Implications of absolute fracture risk assessment for osteoporosis practice guidelines in the USA

Dawson-Hughes, B., Tosteson, A. N. A., Melton, L. J., Baim, S., Favus, M. J., Khosla, S. & Lindsay, R. L., Apr 2008, In : Osteoporosis International. 19, 4, p. 449-458 10 p.

Research output: Contribution to journalArticle

304 Scopus citations

Insulin-like growth factor binding protein-2: A novel regulator of skeletal gender differences?

Khosla, S., May 2008, In : Endocrinology. 149, 5, p. 2048-2050 3 p.

Research output: Contribution to journalArticle

1 Scopus citations

Loss of ERE binding activity by estrogen receptor-α alters basal and estrogen-stimulated bone-related gene expression by osteoblastic cells

Rudnik, V., Sanyal, A., Syed, F. A., Monroe, D. G., Spelsberg, T. C., Oursler, M. J. & Khosla, S., Feb 15 2008, In : Journal of Cellular Biochemistry. 103, 3, p. 896-907 12 p.

Research output: Contribution to journalArticle

15 Scopus citations

Osteocalcin Expression by Circulating Endothelial Progenitor Cells in Patients With Coronary Atherosclerosis

Gössl, M., Mödder, U. I., Atkinson, E. J., Lerman, A. & Khosla, S., Oct 14 2008, In : Journal of the American College of Cardiology. 52, 16, p. 1314-1325 12 p.

Research output: Contribution to journalArticle

117 Scopus citations

Osteoporosis in men

Khosla, S., Amin, S. & Orwoll, E., Jun 2008, In : Endocrine Reviews. 29, 4, p. 441-464 24 p.

Research output: Contribution to journalArticle

237 Scopus citations

Receptor activator of nuclear factor κB ligand and osteoprotegerin regulation of bone remodeling in health and disease

Kearns, A. E., Khosla, S. & Kostenuik, P. J., Apr 2008, In : Endocrine Reviews. 29, 2, p. 155-192 38 p.

Research output: Contribution to journalArticle

520 Scopus citations
316 Scopus citations

Regulation of bone turnover by sex steroids in men

Sanyal, A., Hoey, K. A., Mödder, U. I., Lamsam, J. L., McCready, L. K., Peterson, J. M., Achenbach, S. J., Oursler, M. J. & Khosla, S., May 2008, In : Journal of Bone and Mineral Research. 23, 5, p. 705-714 10 p.

Research output: Contribution to journalArticle

22 Scopus citations