Research output per year
Research output per year
Research output
Search results
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2021
Senolytic Drugs: Reducing Senescent Cell Viability to Extend Health Span
Robbins, P. D., Jurk, D., Khosla, S., Kirkland, J. L., LeBrasseur, N. K., Miller, J. D., Passos, J. F., Pignolo, R. J., Tchkonia, T. & Niedernhofer, L. J., Jan 6 2021, In: Annual Review of Pharmacology and Toxicology. 61, p. 779-803 25 p.Research output: Contribution to journal › Review article › peer-review
1 Scopus citations -
2020
Biomechanical Computed Tomography analysis (BCT) for clinical assessment of osteoporosis
Keaveny, T. M., Clarke, B. L., Cosman, F., Orwoll, E. S., Siris, E. S., Khosla, S. & Bouxsein, M. L., Jun 1 2020, In: Osteoporosis International. 31, 6, p. 1025-1048 24 p.Research output: Contribution to journal › Review article › peer-review
Open Access5 Scopus citations -
Estrogen versus FSH effects on bone metabolism: Evidence from interventional human studies
Khosla, S., 2020, In: Endocrinology (United States). 161, 8, p. 1-9 9 p.Research output: Contribution to journal › Review article › peer-review
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Osteocyte Cellular Senescence
Farr, J. N., Kaur, J., Doolittle, M. L. & Khosla, S., Oct 1 2020, In: Current osteoporosis reports. 18, 5, p. 559-567 9 p.Research output: Contribution to journal › Review article › peer-review
Open Access -
Periodontal disease and senescent cells: New players for an old oral health problem?
Aquino-Martinez, R., Khosla, S., Farr, J. N. & Monroe, D. G., Oct 2 2020, In: International journal of molecular sciences. 21, 20, p. 1-22 22 p., 7441.Research output: Contribution to journal › Review article › peer-review
Open Access1 Scopus citations -
Reducing Senescent Cell Burden in Aging and Disease
Pignolo, R. J., Passos, J. F., Khosla, S., Tchkonia, T. & Kirkland, J. L., Jul 2020, In: Trends in Molecular Medicine. 26, 7, p. 630-638 9 p.Research output: Contribution to journal › Review article › peer-review
12 Scopus citations -
The microbiome adds to the complexity of parathyroid hormone action on bone
Khosla, S., Apr 1 2020, In: Journal of Clinical Investigation. 130, 4, p. 1615-1617 3 p.Research output: Contribution to journal › Review article › peer-review
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The role of cellular senescence in ageing and endocrine disease
Khosla, S., Farr, J. N., Tchkonia, T. & Kirkland, J. L., May 1 2020, In: Nature Reviews Endocrinology. 16, 5, p. 263-275 13 p.Research output: Contribution to journal › Review article › peer-review
26 Scopus citations -
2019
Translation to Practice: Accelerating the Cycle of Innovation to Impact
Anderson, J. R., Chung, T. D. Y., Clark, L., Weis, J. A., Danielsen, A. J., Khosla, S., Gores, G. J. & Badley, A. D., Mar 2019, In: Mayo Clinic proceedings. 94, 3, p. 490-499 10 p.Research output: Contribution to journal › Review article › peer-review
1 Scopus citations -
2018
Regulation of bone metabolism by sex steroids
Khosla, S. & Monroe, D. G., Jan 2018, In: Cold Spring Harbor Perspectives in Medicine. 8, 1, a031211.Research output: Contribution to journal › Review article › peer-review
45 Scopus citations -
2017
Cathepsin K inhibitors for osteoporosis: Biology, potential clinical utility, and lessons learned
Drake, M. T., Clarke, B. L., Oursler, M. J. & Khosla, S., 2017, In: Endocrine reviews. 38, 4, p. 325-350 26 p.Research output: Contribution to journal › Review article › peer-review
76 Scopus citations -
Osteoporosis treatment: recent developments and ongoing challenges
Khosla, S. & Hofbauer, L. C., Nov 2017, In: The Lancet Diabetes and Endocrinology. 5, 11, p. 898-907 10 p.Research output: Contribution to journal › Review article › peer-review
171 Scopus citations -
2016
Determinants of bone strength and quality in diabetes mellitus in humans
Farr, J. N. & Khosla, S., Jan 1 2016, In: Bone. 82, p. 28-34 7 p.Research output: Contribution to journal › Review article › peer-review
87 Scopus citations -
Skeletal metabolism, fracture risk, and fracture outcomes in type 1 and type 2 diabetes
Sellmeyer, D. E., Civitelli, R., Hofbauer, L. C., Khosla, S., Lecka-Czernik, B. & Schwartz, A. V., Jul 1 2016, In: Diabetes. 65, 7, p. 1757-1766 10 p.Research output: Contribution to journal › Review article › peer-review
69 Scopus citations -
2015
Skeletal changes through the lifespan - From growth to senescence
Farr, J. N. & Khosla, S., Sep 20 2015, In: Nature Reviews Endocrinology. 11, 9, p. 513-521 9 p.Research output: Contribution to journal › Review article › peer-review
60 Scopus citations -
2012
Benefits and risks of bisphosphonate therapy for osteoporosis
Khosla, S., Bilezikian, J. P., Dempster, D. W., Lewiecki, E. M., Miller, P. D., Neer, R. M., Recker, R. R., Shane, E., Shoback, D. & Potts, J. T., Jul 2012, In: Journal of Clinical Endocrinology and Metabolism. 97, 7, p. 2272-2282 11 p.Research output: Contribution to journal › Review article › peer-review
164 Scopus citations -
Estrogen and the skeleton
Khosla, S., Oursler, M. J. & Monroe, D. G., Nov 2012, In: Trends in Endocrinology and Metabolism. 23, 11, p. 576-581 6 p.Research output: Contribution to journal › Review article › peer-review
301 Scopus citations -
Male Osteoporosis
Drake, M. T. & Khosla, S., Sep 2012, In: Endocrinology and Metabolism Clinics of North America. 41, 3, p. 629-641 13 p.Research output: Contribution to journal › Review article › peer-review
50 Scopus citations -
Sex- and age-related differences in bone microarchitecture in men relative to women assessed by high-resolution peripheral quantitative computed tomography
Amin, S. & Khosla, S., 2012, In: Journal of Osteoporosis. 2012, 129760.Research output: Contribution to journal › Review article › peer-review
23 Scopus citations -
2011
Emerging therapeutic opportunities for skeletal restoration
Kawai, M., Mödder, U. I., Khosla, S. & Rosen, C. J., Feb 2011, In: Nature Reviews Drug Discovery. 10, 2, p. 141-156 16 p.Research output: Contribution to journal › Review article › peer-review
100 Scopus citations -
Forum on aging and skeletal health: Summary of the proceedings of an ASBMR workshop
Khosla, S., Bellido, T. M., Drezner, M. K., Gordon, C. M., Harris, T. B., Kiel, D. P., Kream, B. E., Leboff, M. S., Lian, J. B., Peterson, C. A., Rosen, C. J., Williams, J. P., Winer, K. K. & Sherman, S. S., Nov 2011, In: Journal of Bone and Mineral Research. 26, 11, p. 2565-2578 14 p.Research output: Contribution to journal › Review article › peer-review
21 Scopus citations -
Osteoporosis: Now and the future
Rachner, T. D., Khosla, S. & Hofbauer, L. C., 2011, In: The Lancet. 377, 9773, p. 1276-1287 12 p.Research output: Contribution to journal › Review article › peer-review
1262 Scopus citations -
Osteoporosis Update From the 2010 Santa Fe Bone Symposium
Lewiecki, E. M., Bilezikian, J. P., Khosla, S., Marcus, R., McClung, M. R., Miller, P. D., Watts, N. B. & Maricic, M., Jan 1 2011, In: Journal of Clinical Densitometry. 14, 1, p. 1-21 21 p.Research output: Contribution to journal › Review article › peer-review
19 Scopus citations -
The unitary model for estrogen deficiency and the pathogenesis of osteoporosis: Is a revision needed?
Khosla, S., Melton, L. J. & Riggs, B. L., Mar 2011, In: Journal of Bone and Mineral Research. 26, 3, p. 441-451 11 p.Research output: Contribution to journal › Review article › peer-review
206 Scopus citations -
2010
Concise review: Insights from normal bone remodeling and stem cell-based therapies for bone repair
Khosla, S., Westendorf, J. J. & Mödder, U. I., Dec 2010, In: Stem Cells. 28, 12, p. 2124-2128 5 p.Research output: Contribution to journal › Review article › peer-review
64 Scopus citations -
Fat tissue, aging, and cellular senescence
Tchkonia, T., Morbeck, D. E., Von Zglinicki, T., Van Deursen, J., Lustgarten, J., Scrable, H., Khosla, S., Jensen, M. D. & Kirkland, J. L., Oct 2010, In: Aging Cell. 9, 5, p. 667-684 18 p.Research output: Contribution to journal › Review article › peer-review
523 Scopus citations -
Female reproductive system and bone
Clarke, B. L. & Khosla, S., Nov 2010, In: Archives of Biochemistry and Biophysics. 503, 1, p. 118-128 11 p.Research output: Contribution to journal › Review article › peer-review
106 Scopus citations -
Physiology of Bone Loss
Clarke, B. L. & Khosla, S., May 2010, In: Radiologic Clinics of North America. 48, 3, p. 483-495 13 p.Research output: Contribution to journal › Review article › peer-review
146 Scopus citations -
Update on estrogens and the skeleton
Khosla, S., Aug 2010, In: Journal of Clinical Endocrinology and Metabolism. 95, 8, p. 3569-3577 9 p.Research output: Contribution to journal › Review article › peer-review
122 Scopus citations -
2009
Bisphosphonate associated osteonecrosis of the jaw
Khan, A. A., Sándor, G. K. B., Dore, E., Morrison, A. D., Alsahli, M., Amin, F., Peters, E., Hanley, D. A., Chaudry, S. R., Lentle, B., Dempster, D. W., Glorieux, F. H., Neville, A. J., Talwar, R. M., Clokie, C. M., Al Mardini, M., Paul, T., Khosla, S., Josse, R. G., Sutherland, S. & 10 others, , Mar 2009, In: Journal of Rheumatology. 36, 3, p. 478-490 13 p.Research output: Contribution to journal › Review article › peer-review
124 Scopus citations -
Mesenchymal stem cells for bone repair and metabolic bone diseases
Undale, A. H., Westendorf, J. J., Yaszemski, M. J. & Khosla, S., Oct 2009, In: Mayo Clinic proceedings. 84, 10, p. 893-902 10 p.Research output: Contribution to journal › Review article › peer-review
138 Scopus citations -
New selective estrogen and androgen receptor modulators
Clarke, B. L. & Khosla, S., Jul 2009, In: Current opinion in rheumatology. 21, 4, p. 374-379 6 p.Research output: Contribution to journal › Review article › peer-review
29 Scopus citations -
Targeting bone remodeling for the treatment of osteoporosis: summary of the proceedings of an ASBMR workshop
Bilezikian, J. P., Matsumoto, T., Bellido, T., Khosla, S., Martin, J., Recker, R. R., Heaney, R., Seeman, E., Papapoulos, S. & Goldring, S. R., Mar 2009, In: Journal of Bone and Mineral Research. 24, 3, p. 373-385 13 p.Research output: Contribution to journal › Review article › peer-review
44 Scopus citations -
2008
Bisphosphonates: Mechanism of action and role in clinical practice
Drake, M. T., Clarke, B. L. & Khosla, S., Sep 2008, In: Mayo Clinic proceedings. 83, 9, p. 1032-1045 14 p.Research output: Contribution to journal › Review article › peer-review
714 Scopus citations -
Building bone to reverse osteoporosis and repair fractures
Khosla, S., Westendorf, J. J. & Oursler, M. J., Feb 1 2008, In: Journal of Clinical Investigation. 118, 2, p. 421-428 8 p.Research output: Contribution to journal › Review article › peer-review
293 Scopus citations -
Osteoporosis in men
Khosla, S., Amin, S. & Orwoll, E., Jun 2008, In: Endocrine reviews. 29, 4, p. 441-464 24 p.Research output: Contribution to journal › Review article › peer-review
254 Scopus citations -
Receptor activator of nuclear factor κB ligand and osteoprotegerin regulation of bone remodeling in health and disease
Kearns, A. E., Khosla, S. & Kostenuik, P. J., Apr 2008, In: Endocrine reviews. 29, 2, p. 155-192 38 p.Research output: Contribution to journal › Review article › peer-review
560 Scopus citations -
2007
Bisphosphonate-associated osteonecrosis of the jaw: Report of a Task Force of the American Society for Bone and Mineral Research
Khosla, S., Burr, D., Cauley, J., Dempster, D. W., Ebeling, P. R., Felsenberg, D., Gagel, R. F., Gilsanz, V., Guise, T., Koka, S., McCauley, L. K., McGowan, J., McKee, M. D., Mohla, S., Pendrys, D. G., Raisz, L. G., Ruggiero, S. L., Shafer, D. M., Shum, L., Silverman, S. L. & 4 others, , Oct 2007, In: Journal of Bone and Mineral Research. 22, 10, p. 1479-1491 13 p.Research output: Contribution to journal › Review article › peer-review
1221 Scopus citations -
Remodeling and vascular spaces in bone
Eriksen, E. F., Eghbali-Fatourechi, G. Z. & Khosla, S., Jan 2007, In: Journal of Bone and Mineral Research. 22, 1, p. 1-6 6 p.Research output: Contribution to journal › Review article › peer-review
122 Scopus citations -
2006
Bone fragility in men - Where are we?
Seeman, E., Bianchi, G., Khosla, S., Kanis, J. A. & Orwoll, E., Nov 1 2006, In: Osteoporosis International. 17, 11, p. 1577-1583 7 p.Research output: Contribution to journal › Review article › peer-review
79 Scopus citations -
Systemic assessments utilizing saliva: Part 2 - Osteoporosis and use of saliva to measure bone turnover
Koka, S., Forde, M. D. & Khosla, S., Jan 1 2006, In: International Journal of Prosthodontics. 19, 1, p. 53-60 8 p.Research output: Contribution to journal › Review article › peer-review
16 Scopus citations -
The classical estrogen receptor transcriptional pathway: Implications in human osteoblasts
Monroe, D. G., Secreto, F. J., Khosla, S. & Spelsberg, T. C., 2006, In: Clinical Reviews in Bone and Mineral Metabolism. 4, 2, p. 129-140 12 p.Research output: Contribution to journal › Review article › peer-review
1 Scopus citations -
2005
Evaluation of a prediction model for long-term fracture risk
Melton, L. J., Atkinson, E. J., Khosla, S., Oberg, A. L. & Lawrence Riggs, B., Apr 2005, In: Journal of Bone and Mineral Research. 20, 4, p. 551-556 6 p.Research output: Contribution to journal › Review article › peer-review
26 Scopus citations -
Mechanisms of sex steroid effects on bone
Syed, F. & Khosla, S., Mar 18 2005, In: Biochemical and Biophysical Research Communications. 328, 3, p. 688-696 9 p.Research output: Contribution to journal › Review article › peer-review
281 Scopus citations -
Pathophysiology of age-related bone loss and osteoporosis
Khosla, S. & Riggs, B. L., Dec 1 2005, In: Endocrinology and Metabolism Clinics of North America. 34, 4, p. 1015-1030 16 p.Research output: Contribution to journal › Review article › peer-review
199 Scopus citations -
Potential role of pancreatic and enteric hormones in regulating bone turnover
Clowes, J. A., Khosla, S. & Eastell, R., Sep 1 2005, In: Journal of Bone and Mineral Research. 20, 9, p. 1497-1506 10 p.Research output: Contribution to journal › Review article › peer-review
70 Scopus citations -
The role of the immune system in the pathophysiology of osteoporosis
Clowes, J. A., Riggs, B. L. & Khosla, S., Dec 2005, In: Immunological Reviews. 208, p. 207-227 21 p.Research output: Contribution to journal › Review article › peer-review
248 Scopus citations -
2004
Potential Anabolic Effects of Androgens on Bone
Kearns, A. E. & Khosla, S., Apr 2004, In: Mayo Clinic proceedings. 79, 4 SUPPL., p. S14-S18Research output: Contribution to journal › Review article › peer-review
9 Scopus citations -
2003
The role of estrogens in men and androgens in women
Khosla, S. & Bilezikian, J. P., Feb 2003, In: Endocrinology and Metabolism Clinics of North America. 32, 1, p. 195-218 24 p.Research output: Contribution to journal › Review article › peer-review
33 Scopus citations -
2002
Clinical review 144: Estrogen and the male skeleton
Khosla, S., Joseph Melton, L. & Lawrence Riggs, B., 2002, In: Journal of Clinical Endocrinology and Metabolism. 87, 4, p. 1443-1450 8 p.Research output: Contribution to journal › Review article › peer-review
254 Scopus citations