• 41264 Citations
  • 103 Scopus h-Index
1980 …2020

Research output per year

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Research Output

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Review article
2020

Biomechanical Computed Tomography analysis (BCT) for clinical assessment of osteoporosis

Keaveny, T. M., Clarke, B. L., Cosman, F., Orwoll, E. S., Siris, E. S., Khosla, S. & Bouxsein, M. L., Jun 1 2020, In : Osteoporosis International. 31, 6, p. 1025-1048 24 p.

Research output: Contribution to journalReview article

Open Access
2 Scopus citations

Reducing Senescent Cell Burden in Aging and Disease

Pignolo, R. J., Passos, J. F., Khosla, S., Tchkonia, T. & Kirkland, J. L., Jul 2020, In : Trends in Molecular Medicine. 26, 7, p. 630-638 9 p.

Research output: Contribution to journalReview article

1 Scopus citations

The microbiome adds to the complexity of parathyroid hormone action on bone

Khosla, S., Apr 1 2020, In : Journal of Clinical Investigation. 130, 4, p. 1615-1617 3 p.

Research output: Contribution to journalReview article

The role of cellular senescence in ageing and endocrine disease

Khosla, S., Farr, J. N., Tchkonia, T. & Kirkland, J. L., May 1 2020, In : Nature Reviews Endocrinology. 16, 5, p. 263-275 13 p.

Research output: Contribution to journalReview article

6 Scopus citations
2019

Translation to Practice: Accelerating the Cycle of Innovation to Impact

Anderson, J. R., Chung, T. D. Y., Clark, L., Weis, J. A., Danielsen, A. J., Khosla, S., Gores, G. J. & Badley, A. D., Jan 1 2019, In : Mayo Clinic proceedings.

Research output: Contribution to journalReview article

1 Scopus citations
2018

Regulation of bone metabolism by sex steroids

Khosla, S. & Monroe, D. G., Jan 2018, In : Cold Spring Harbor Perspectives in Medicine. 8, 1, a031211.

Research output: Contribution to journalReview article

30 Scopus citations
2017

Cathepsin K Inhibitors for Osteoporosis: Biology, Potential Clinical Utility, and Lessons Learned

Drake, M. M., Clarke, B., Oursler, M. J. & Khosla, S., Aug 1 2017, In : Endocrine Reviews. 38, 4, p. 325-350 26 p.

Research output: Contribution to journalReview article

59 Scopus citations
2016

Skeletal metabolism, fracture risk, and fracture outcomes in type 1 and type 2 diabetes

Sellmeyer, D. E., Civitelli, R., Hofbauer, L. C., Khosla, S., Lecka-Czernik, B. & Schwartz, A. V., Jul 1 2016, In : Diabetes. 65, 7, p. 1757-1766 10 p.

Research output: Contribution to journalReview article

60 Scopus citations
2012

Benefits and risks of bisphosphonate therapy for osteoporosis

Khosla, S., Bilezikian, J. P., Dempster, D. W., Lewiecki, E. M., Miller, P. D., Neer, R. M., Recker, R. R., Shane, E., Shoback, D. & Potts, J. T., Jul 1 2012, In : Journal of Clinical Endocrinology and Metabolism. 97, 7, p. 2272-2282 11 p.

Research output: Contribution to journalReview article

157 Scopus citations

Estrogen and the skeleton

Khosla, S., Oursler, M. J. & Monroe, D. G., Nov 1 2012, In : Trends in Endocrinology and Metabolism. 23, 11, p. 576-581 6 p.

Research output: Contribution to journalReview article

253 Scopus citations

Male Osteoporosis

Drake, M. T. & Khosla, S., Sep 1 2012, In : Endocrinology and Metabolism Clinics of North America. 41, 3, p. 629-641 13 p.

Research output: Contribution to journalReview article

47 Scopus citations
21 Scopus citations
2011

Emerging therapeutic opportunities for skeletal restoration

Kawai, M., Mödder, U. I., Khosla, S. & Rosen, C. J., Feb 1 2011, In : Nature Reviews Drug Discovery. 10, 2, p. 141-156 16 p.

Research output: Contribution to journalReview article

92 Scopus citations

Forum on aging and skeletal health: Summary of the proceedings of an ASBMR workshop

Khosla, S., Bellido, T. M., Drezner, M. K., Gordon, C. M., Harris, T. B., Kiel, D. P., Kream, B. E., Leboff, M. S., Lian, J. B., Peterson, C. A., Rosen, C. J., Williams, J. P., Winer, K. K. & Sherman, S. S., Nov 1 2011, In : Journal of Bone and Mineral Research. 26, 11, p. 2565-2578 14 p.

Research output: Contribution to journalReview article

20 Scopus citations

Osteoporosis: Now and the future

Rachner, T. D., Khosla, S. & Hofbauer, L. C., Jan 1 2011, In : The Lancet. 377, 9773, p. 1276-1287 12 p.

Research output: Contribution to journalReview article

1156 Scopus citations

Osteoporosis Update From the 2010 Santa Fe Bone Symposium

Lewiecki, E. M., Bilezikian, J. P., Khosla, S., Marcus, R., McClung, M. R., Miller, P. D., Watts, N. B. & Maricic, M., Jan 1 2011, In : Journal of Clinical Densitometry. 14, 1, p. 1-21 21 p.

Research output: Contribution to journalReview article

19 Scopus citations

The unitary model for estrogen deficiency and the pathogenesis of osteoporosis: Is a revision needed?

Khosla, S., Melton, L. J. & Riggs, B. L., Mar 1 2011, In : Journal of Bone and Mineral Research. 26, 3, p. 441-451 11 p.

Research output: Contribution to journalReview article

190 Scopus citations
2010

Concise review: Insights from normal bone remodeling and stem cell-based therapies for bone repair

Khosla, S., Westendorf, J. J. & Mödder, U. I., Dec 1 2010, In : Stem Cells. 28, 12, p. 2124-2128 5 p.

Research output: Contribution to journalReview article

64 Scopus citations

Fat tissue, aging, and cellular senescence

Tchkonia, T., Morbeck, D. E., Von Zglinicki, T., Van Deursen, J., Lustgarten, J., Scrable, H., Khosla, S., Jensen, M. D. & Kirkland, J. L., Oct 2010, In : Aging Cell. 9, 5, p. 667-684 18 p.

Research output: Contribution to journalReview article

462 Scopus citations

Female reproductive system and bone

Clarke, B. L. & Khosla, S., Nov 1 2010, In : Archives of Biochemistry and Biophysics. 503, 1, p. 118-128 11 p.

Research output: Contribution to journalReview article

99 Scopus citations

Physiology of Bone Loss

Clarke, B. L. & Khosla, S., May 1 2010, In : Radiologic Clinics of North America. 48, 3, p. 483-495 13 p.

Research output: Contribution to journalReview article

133 Scopus citations

Update on estrogens and the skeleton

Khosla, S., Aug 2010, In : Journal of Clinical Endocrinology and Metabolism. 95, 8, p. 3569-3577 9 p.

Research output: Contribution to journalReview article

117 Scopus citations
2009

Bisphosphonate associated osteonecrosis of the jaw

Khan, A. A., Sándor, G. K. B., Dore, E., Morrison, A. D., Alsahli, M., Amin, F., Peters, E., Hanley, D. A., Chaudry, S. R., Lentle, B., Dempster, D. W., Glorieux, F. H., Neville, A. J., Talwar, R. M., Clokie, C. M., Al Mardini, M., Paul, T., Khosla, S., Josse, R. G., Sutherland, S. & 10 others, Lam, D. K., Carmichael, R. P., Blanas, N., Kendler, D., Petak, S., Ste-Marie, L. G., Brown, J., Evans, A. W., Rios, L. & Compston, J. E., Mar 1 2009, In : Journal of Rheumatology. 36, 3, p. 478-490 13 p.

Research output: Contribution to journalReview article

122 Scopus citations

Mesenchymal stem cells for bone repair and metabolic bone diseases

Undale, A. H., Westendorf, J. J., Yaszemski, M. J. & Khosla, S., Oct 2009, In : Mayo Clinic proceedings. 84, 10, p. 893-902 10 p.

Research output: Contribution to journalReview article

133 Scopus citations

New selective estrogen and androgen receptor modulators

Clarke, B. L. & Khosla, S., Jul 1 2009, In : Current opinion in rheumatology. 21, 4, p. 374-379 6 p.

Research output: Contribution to journalReview article

29 Scopus citations

Targeting bone remodeling for the treatment of osteoporosis: summary of the proceedings of an ASBMR workshop

Bilezikian, J. P., Matsumoto, T., Bellido, T., Khosla, S., Martin, J., Recker, R. R., Heaney, R., Seeman, E., Papapoulos, S. & Goldring, S. R., Mar 1 2009, In : Journal of Bone and Mineral Research. 24, 3, p. 373-385 13 p.

Research output: Contribution to journalReview article

43 Scopus citations
2008

Bisphosphonates: Mechanism of action and role in clinical practice

Drake, M. T., Clarke, B. L. & Khosla, S., Sep 2008, In : Mayo Clinic proceedings. 83, 9, p. 1032-1045 14 p.

Research output: Contribution to journalReview article

649 Scopus citations

Building bone to reverse osteoporosis and repair fractures

Khosla, S., Westendorf, J. J. & Oursler, M. J., Feb 1 2008, In : Journal of Clinical Investigation. 118, 2, p. 421-428 8 p.

Research output: Contribution to journalReview article

282 Scopus citations

Osteoporosis in men

Khosla, S., Amin, S. & Orwoll, E., Jun 2008, In : Endocrine reviews. 29, 4, p. 441-464 24 p.

Research output: Contribution to journalReview article

241 Scopus citations

Receptor activator of nuclear factor κB ligand and osteoprotegerin regulation of bone remodeling in health and disease

Kearns, A. E., Khosla, S. & Kostenuik, P. J., Apr 1 2008, In : Endocrine reviews. 29, 2, p. 155-192 38 p.

Research output: Contribution to journalReview article

536 Scopus citations
2007

Bisphosphonate-associated osteonecrosis of the jaw: Report of a Task Force of the American Society for Bone and Mineral Research

Khosla, S., Burr, D., Cauley, J., Dempster, D. W., Ebeling, P. R., Felsenberg, D., Gagel, R. F., Gilsanz, V., Guise, T., Koka, S., McCauley, L. K., McGowan, J., McKee, M. D., Mohla, S., Pendrys, D. G., Raisz, L. G., Ruggiero, S. L., Shafer, D. M., Shum, L., Silverman, S. L. & 4 others, Van Poznak, C. H., Watts, N., Woo, S. B. & Shane, E., Oct 1 2007, In : Journal of Bone and Mineral Research. 22, 10, p. 1479-1491 13 p.

Research output: Contribution to journalReview article

1190 Scopus citations

Remodeling and vascular spaces in bone

Eriksen, E. F., Eghbali-Fatourechi, G. Z. & Khosla, S., Jan 1 2007, In : Journal of Bone and Mineral Research. 22, 1, p. 1-6 6 p.

Research output: Contribution to journalReview article

120 Scopus citations
2006

Bone fragility in men - Where are we?

Seeman, E., Bianchi, G., Khosla, S., Kanis, J. A. & Orwoll, E., Nov 1 2006, In : Osteoporosis International. 17, 11, p. 1577-1583 7 p.

Research output: Contribution to journalReview article

77 Scopus citations

Systemic assessments utilizing saliva: Part 2 - Osteoporosis and use of saliva to measure bone turnover

Koka, S., Forde, M. D. & Khosla, S., Jan 1 2006, In : International Journal of Prosthodontics. 19, 1, p. 53-60 8 p.

Research output: Contribution to journalReview article

16 Scopus citations

The classical estrogen receptor transcriptional pathway: Implications in human osteoblasts

Monroe, D. G., Secreto, F. J., Khosla, S. & Spelsberg, T. C., May 31 2006, In : Clinical Reviews in Bone and Mineral Metabolism. 4, 2, p. 129-140 12 p.

Research output: Contribution to journalReview article

1 Scopus citations
2005

Evaluation of a prediction model for long-term fracture risk

Melton, L. J., Atkinson, E. J., Khosla, S., Oberg, A. L. & Lawrence Riggs, B., Apr 1 2005, In : Journal of Bone and Mineral Research. 20, 4, p. 551-556 6 p.

Research output: Contribution to journalReview article

25 Scopus citations

Mechanisms of sex steroid effects on bone

Syed, F. & Khosla, S., Mar 18 2005, In : Biochemical and Biophysical Research Communications. 328, 3, p. 688-696 9 p.

Research output: Contribution to journalReview article

277 Scopus citations

Pathophysiology of age-related bone loss and osteoporosis

Khosla, S. & Riggs, B. L., Dec 1 2005, In : Endocrinology and Metabolism Clinics of North America. 34, 4, p. 1015-1030 16 p.

Research output: Contribution to journalReview article

191 Scopus citations

Potential role of pancreatic and enteric hormones in regulating bone turnover

Clowes, J. A., Khosla, S. & Eastell, R., Sep 1 2005, In : Journal of Bone and Mineral Research. 20, 9, p. 1497-1506 10 p.

Research output: Contribution to journalReview article

69 Scopus citations

The role of the immune system in the pathophysiology of osteoporosis

Clowes, J. A., Riggs, B. L. & Khosla, S., Dec 1 2005, In : Immunological Reviews. 208, p. 207-227 21 p.

Research output: Contribution to journalReview article

238 Scopus citations
2004

Potential Anabolic Effects of Androgens on Bone

Kearns, A. E. & Khosla, S., Apr 2004, In : Mayo Clinic proceedings. 79, 4 SUPPL., p. S14-S18

Research output: Contribution to journalReview article

9 Scopus citations
2003

The role of estrogens in men and androgens in women

Khosla, S. & Bilezikian, J. P., Feb 2003, In : Endocrinology and Metabolism Clinics of North America. 32, 1, p. 195-218 24 p.

Research output: Contribution to journalReview article

32 Scopus citations
2002

Clinical review 144: Estrogen and the male skeleton

Khosla, S., Joseph Melton, L. & Lawrence Riggs, B., Jun 20 2002, In : Journal of Clinical Endocrinology and Metabolism. 87, 4, p. 1443-1450 8 p.

Research output: Contribution to journalReview article

248 Scopus citations

Sex steroids and the construction and conservation of the adult skeleton

Riggs, B. L., Khosla, S. & Melton, L. J., Jan 1 2002, In : Endocrine Reviews. 23, 3, p. 279-302 24 p.

Research output: Contribution to journalReview article

1261 Scopus citations
2000

The roles of osteoprotegerin and osteoprotegerin ligand in the paracrine regulation of bone resorption

Hofbauer, L. C., Khosla, S., Dunstan, C. R., Lacey, D. L., Boyle, W. J. & Riggs, B. L., Jan 1 2000, In : Journal of Bone and Mineral Research. 15, 1, p. 2-12 11 p.

Research output: Contribution to journalReview article

950 Scopus citations
1999

Androgen effects on bone metabolism: Recent progress and controversies

Hofbauer, L. C. & Khosla, S., Apr 1 1999, In : European journal of endocrinology. 140, 4, p. 271-286 16 p.

Research output: Contribution to journalReview article

115 Scopus citations
1998

Idiopathic osteoporosis: A heterogeneous entity

Heshmati, H. M. & Khosla, S., Mar 1 1998, In : Annales de Medecine Interne. 149, 2, p. 77-81 5 p.

Research output: Contribution to journalReview article

16 Scopus citations
1997

Update on primary osteoporosis

Hurley, D. L. & Khosla, S., 1997, In : Mayo Clinic proceedings. 72, 10, p. 943-949 7 p.

Research output: Contribution to journalReview article

14 Scopus citations