Research Output 1976 2020

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Review article
2019
8 Citations (Scopus)

Apolipoprotein E and Alzheimer disease: pathobiology and targeting strategies

Yamazaki, Y., Zhao, N., Caulfield, T., Liu, C-C. & Bu, G. D., Sep 1 2019, In : Nature Reviews Neurology. 15, 9, p. 501-518 18 p.

Research output: Contribution to journalReview article

Apolipoproteins E
Alzheimer Disease
Apolipoprotein E4
Alleles
Pathology
1 Citation (Scopus)

Cellular models of alpha-synuclein toxicity and aggregation

Delenclos, M., Burgess, J. D., Lamprokostopoulou, A., Outeiro, T. F., Vekrellis, K. & McLean, P. J., Jan 1 2019, In : Journal of neurochemistry. 150, 5, p. 566-576 11 p.

Research output: Contribution to journalReview article

Open Access
Synucleins
alpha-Synuclein
Toxicity
Agglomeration
Neurons
5 Citations (Scopus)

CNS small vessel disease: A clinical review

Cannistraro, R. J., Badi, M., Eidelman, B. H., Dickson, D. W., Middlebrooks, E. H. & Meschia, J. F., Jun 11 2019, In : Neurology. 92, 24, p. 1146-1156 11 p.

Research output: Contribution to journalReview article

Dementia
Cerebral Amyloid Angiopathy
Hypertension
Inborn Genetic Diseases
Diffusion Tensor Imaging
9 Citations (Scopus)

Genetic Convergence Brings Clarity to the Enigmatic Red Line in ALS

Cook, C. & Petrucelli, L., Mar 20 2019, In : Neuron. 101, 6, p. 1057-1069 13 p.

Research output: Contribution to journalReview article

Amyotrophic Lateral Sclerosis
Neurodegenerative Diseases
Quality Control
Nervous System
Genes
6 Citations (Scopus)

The neuropathological diagnosis of Alzheimer's disease

Deture, M. & Dickson, D. W., Aug 2 2019, In : Molecular neurodegeneration. 14, 1, 32.

Research output: Contribution to journalReview article

Open Access
Alzheimer Disease
Cerebrovascular Disorders
Lewy Body Disease
Pathology
TDP-43 Proteinopathies
1 Citation (Scopus)

The unresolved role of mitochondrial DNA in Parkinson's disease: An overview of published studies, their limitations, and future prospects

Müller-Nedebock, A. C., Brennan, R. R., Venter, M., Pienaar, I. S., van der Westhuizen, F. H., Elson, J. L., Ross, O. A. & Bardien, S., Oct 1 2019, In : Neurochemistry International. 129, 104495.

Research output: Contribution to journalReview article

Mitochondrial DNA
Parkinson Disease
Mitochondria
Adenosine Triphosphate
Mitochondrial Genome
2018
16 Citations (Scopus)

ABCA7 and pathogenic pathways of Alzheimer’s disease

Aikawa, T., Holm, M. L. & Kanekiyo, T., Feb 1 2018, In : Brain Sciences. 8, 2, 27.

Research output: Contribution to journalReview article

Alzheimer Disease
Amyloid beta-Protein Precursor
Nonsense Codon
Medical Genetics
Brain
74 Citations (Scopus)

Age and age-related diseases: Role of inflammation triggers and cytokines

Rea, I. M., Gibson, D. S., McGilligan, V., McNerlan, S. E., Denis Alexander, H. & Ross, O. A., Apr 9 2018, In : Frontiers in Immunology. 9, APR, 586.

Research output: Contribution to journalReview article

Cytokines
Inflammation
Rheumatoid Arthritis
Inflammasomes
Phenotype
7 Citations (Scopus)
Amyloid
Alzheimer Disease
Infection
Disease Progression
Microbial Interactions
7 Citations (Scopus)

Atypical parkinsonian syndromes: a general neurologist's perspective

Deutschländer, A. B., Ross, O. A., Dickson, D. W. & Wszolek, Z. K., Jan 1 2018, In : European Journal of Neurology. 25, 1, p. 41-58 18 p.

Research output: Contribution to journalReview article

Frontotemporal Lobar Degeneration
Parkinsonian Disorders
Frontotemporal Dementia
Primary Progressive Aphasia
Progressive Supranuclear Palsy
30 Citations (Scopus)

Converging pathways in neurodegeneration, from genetics to mechanisms

Gan, L., Cookson, M. R., Petrucelli, L. & La Spada, A. R., Oct 1 2018, In : Nature Neuroscience. 21, 10, p. 1300-1309 10 p.

Research output: Contribution to journalReview article

Neurodegenerative Diseases
Medical Genetics
Rare Diseases
Innate Immunity
Quality Control
8 Citations (Scopus)

CSF1R-related leukoencephalopathy: A major player in primary microgliopathies

Konno, T., Kasanuki, K., Ikeuchi, T., Dickson, D. W. & Wszolek, Z. K., Dec 11 2018, In : Neurology. 91, 24, p. 1092-1104 13 p.

Research output: Contribution to journalReview article

Colony-Stimulating Factor Receptors
Leukoencephalopathies
Macrophage Colony-Stimulating Factor
Microglia
Mutation
15 Citations (Scopus)

Potentially Modifiable Risk Factors for Long-Term Cognitive Impairment After Critical Illness: A Systematic Review

Sakusic, A., O'Horo, J. C., Dziadzko, M., Volha, D., Ali, R., Singh, T. D., Kashyap, R., Farrell, A. M., Fryer, J. D., Petersen, R. C., Gajic, O. & Rabinstein, A., Jan 1 2018, In : Mayo Clinic Proceedings. 93, 1, p. 68-82 15 p.

Research output: Contribution to journalReview article

Critical Illness
Intensive Care Units
Delirium
Critical Care
Survivors
18 Citations (Scopus)

Recent advances in neuropathology, biomarkers and therapeutic approach of multiple system atrophy

Koga, S. & Dickson, D. W., Feb 1 2018, In : Journal of Neurology, Neurosurgery and Psychiatry. 89, 2, p. 175-184 10 p.

Research output: Contribution to journalReview article

Multiple System Atrophy
Biomarkers
Inclusion Bodies
Striatonigral Degeneration
Therapeutics
5 Citations (Scopus)

Slowly progressive dementia caused by MAPT R406W mutations: Longitudinal report on a new kindred and systematic review

Ygland, E., Van Westen, D., Englund, E., Rademakers, R. V., Wszolek, Z. K., Nilsson, K., Nilsson, C., Landqvist Waldö, M., Alafuzoff, I., Hansson, O., Gustafson, L. & Puschmann, A., Jan 9 2018, In : Alzheimer's Research and Therapy. 10, 1, 2.

Research output: Contribution to journalReview article

Dementia
Temporal Lobe
Mutation
Tauopathies
Behavioral Symptoms
2017
22 Citations (Scopus)

Alzheimer's Disease-Related Dementias Summit 2016: National research priorities

Corriveau, R. A., Koroshetz, W. J., Gladman, J. T., Jeon, S., Babcock, D., Bennett, D. A., Carmichael, S. T., Dickinson, S. L. J., Dickson, D. W., Emr, M., Fillit, H., Greenberg, S. M., Hutton, M. L., Knopman, D. S., Manly, J. J., Marder, K. S., Moy, C. S., Phelps, C. H., Scott, P. A., Seeley, W. W. & 8 others, Sieber, B. A., Silverberg, N. B., Sutherland, M. L., Taylor, A., Torborg, C. L., Waddy, S. P., Gubitz, A. K. & Holtzman, D. M., Dec 5 2017, In : Neurology. 89, 23, p. 2381-2391 11 p.

Research output: Contribution to journalReview article

Dementia
Alzheimer Disease
Research
Lewy Body Disease
Terminology
33 Citations (Scopus)

Apolipoprotein e metabolism and functions in brain and its role in Alzheimer's disease

Liao, F., Yoon, H. & Kim, J., 2017, In : Current Opinion in Lipidology. 28, 1, p. 60-67 8 p.

Research output: Contribution to journalReview article

Apolipoproteins
Apolipoproteins E
Amyloid
Alzheimer Disease
Brain
42 Citations (Scopus)

Blood-brain barrier dysfunction and the pathogenesis of alzheimer’s disease

Yamazaki, Y. & Kanekiyo, T., Sep 13 2017, In : International Journal of Molecular Sciences. 18, 9, 1965.

Research output: Contribution to journalReview article

blood-brain barrier
pathogenesis
Blood-Brain Barrier
Alzheimer Disease
brain
11 Citations (Scopus)

LRRK2 mouse models: Dissecting the behavior, striatal neurochemistry and neurophysiology of PD pathogenesis

Volta, M. & Melrose, H. L., Feb 8 2017, In : Biochemical Society Transactions. 45, 1, p. 113-122 10 p.

Research output: Contribution to journalReview article

Neurophysiology
Neurochemistry
Corpus Striatum
Leucine
Parkinson Disease
37 Citations (Scopus)

Pathology of neurodegenerative diseases

Dugger, B. N. & Dickson, D. W., Jan 1 2017, In : Cold Spring Harbor perspectives in biology. 9, 7, a028035.

Research output: Contribution to journalReview article

Neurodegenerative diseases
Pathology
Neurodegenerative Diseases
Neurons
Poisons
54 Citations (Scopus)

PINK1, Parkin, and Mitochondrial Quality Control: What can we Learn about Parkinson's Disease Pathobiology?

Truban, D., Hou, X., Caulfield, T., Fiesel, F. & Springer, W., 2017, In : Journal of Parkinson's Disease. 7, 1, p. 13-29 17 p.

Research output: Contribution to journalReview article

Quality Control
Parkinson Disease
Phosphotransferases
Mitochondrial Degradation
Ubiquitin-Protein Ligases
32 Citations (Scopus)

Role of LRP1 in the pathogenesis of Alzheimer's disease: Evidence from clinical and preclinical studies

Shinohara, M., Tachibana, M., Kanekiyo, T. & Bu, G. D., 2017, In : Journal of Lipid Research. 58, 7, p. 1267-1281 15 p.

Research output: Contribution to journalReview article

Alzheimer Disease
Brain
Low Density Lipoprotein Receptor-Related Protein-1
Clinical Studies
LDL Receptors
2016
55 Citations (Scopus)

Genetics of FTLD: overview and what else we can expect from genetic studies

Pottier, C., Ravenscroft, T. A., Sanchez-Contreras, M. & Rademakers, R. V., Aug 1 2016, In : Journal of Neurochemistry. p. 32-53 22 p.

Research output: Contribution to journalReview article

Frontotemporal Lobar Degeneration
Genes
Genetic Research
Genetics
Microtubule-Associated Proteins
5 Citations (Scopus)
Clinical Pathology
Pathology
Dementia
Craniocerebral Trauma
Sex Characteristics
34 Citations (Scopus)

Insights into the pathogenic mechanisms of Chromosome 9 open reading frame 72 (C9orf72) repeat expansions

Todd, T. W. & Petrucelli, L., Aug 1 2016, In : Journal of Neurochemistry. p. 145-162 18 p.

Research output: Contribution to journalReview article

Chromosomes, Human, Pair 9
Chromosomes
Open Reading Frames
Neurology
RNA
10 Citations (Scopus)

TREMs in Alzheimer's disease: Genetic and clinical investigations

Cheng, J., Guo, X. F., Zhang, T., Zhong, L., Bu, G. D. & Chen, X. F., Dec 1 2016, In : Clinica Chimica Acta. 463, p. 88-95 8 p.

Research output: Contribution to journalReview article

Alzheimer Disease
Cerebrospinal fluid
Myeloid Cells
Multigene Family
Innate Immunity
2014
61 Citations (Scopus)

Apolipoprotein E in synaptic plasticity and alzheimer’s disease: Potential cellular and molecular mechanisms

Kim, J., Yoon, H., Basak, J. & Kim, J., Nov 1 2014, In : Molecules and Cells. 37, 11, p. 833-840 8 p.

Research output: Contribution to journalReview article

Neuronal Plasticity
Apolipoproteins E
Alzheimer Disease
Apolipoprotein E4
Memory Disorders
53 Citations (Scopus)

Dysregulation of protein trafficking in neurodegeneration

Wang, X., Huang, T., Bu, G. D. & Xu, H., 2014, In : Molecular Neurodegeneration. 9, p. 31 1 p.

Research output: Contribution to journalReview article

Protein Transport
Alzheimer Disease
Down Syndrome
Amyloid beta-Protein Precursor
Neurodegenerative Diseases
2004
146 Citations (Scopus)

Apoptotic mechanisms in Alzheimer neurofibrillary degeneration: Cause or effect?

Dickson, D. W., Jan 1 2004, In : Journal of Clinical Investigation. 114, 1, p. 23-27 5 p.

Research output: Contribution to journalReview article

Aspartic Acid Proteases
Cysteine Proteases
Amyloidogenic Proteins
tau Proteins
Cytoskeletal Proteins
2002
32 Citations (Scopus)

The clinical relevance of antidepressant interaction with neurotransmitter transporters and receptors

Richelson, E., Sep 1 2002, In : Psychopharmacology Bulletin. 36, 4, p. 133-150 18 p.

Research output: Contribution to journalReview article

Neurotransmitter Transport Proteins
Neurotransmitter Receptor
Antidepressive Agents
Pharmacology
Norepinephrine Plasma Membrane Transport Proteins