Research Output

2019

Heterochromatin anomalies and double-stranded RNA accumulation underlie C9orf72 poly(PR) toxicity

Zhang, Y. J., Guo, L., Gonzales, P. K., Gendron, T. F., Wu, Y., Jansen-West, K., O’Raw, A. D., Pickles, S. R., Prudencio, M., Carlomagno, Y., Gachechiladze, M. A., Ludwig, C., Tian, R., Chew, J., DeTure, M., Lin, W. L., Tong, J., Daughrity, L. M., Yue, M., Song, Y. & 15 others, Andersen, J. W., Castanedes-Casey, M., Kurti, A., Datta, A., Antognetti, G., McCampbell, A., Rademakers, R., Oskarsson, B., Dickson, D. W., Kampmann, M., Ward, M. E., Fryer, J. D., Link, C. D., Shorter, J. & Petrucelli, L., Feb 15 2019, In : Science. 363, 6428, eaav2606.

Research output: Contribution to journalArticle

31 Scopus citations

Identification of evolutionarily conserved gene networks mediating neurodegenerative dementia

International Frontotemporal Dementia Genomics Consortium, Jan 1 2019, In : Nature Medicine. 25, 1, p. 152-164 13 p.

Research output: Contribution to journalArticle

10 Scopus citations

Increased Immune Activation by Pathologic α-Synuclein in Parkinson's Disease

Grozdanov, V., Bousset, L., Hoffmeister, M., Bliederhaeuser, C., Meier, C., Madiona, K., Pieri, L., Kiechle, M., McLean, P. J., Kassubek, J., Behrends, C., Ludolph, A. C., Weishaupt, J. H., Melki, R. & Danzer, K. M., Oct 1 2019, In : Annals of neurology. 86, 4, p. 593-606 14 p.

Research output: Contribution to journalArticle

Open Access
5 Scopus citations

Integrative data fusion for comprehensive assessment of a novel CHEK2 variant using combined genomics, imaging, and functional-structural assessments via protein informatics

Hines, S. L., Mohammad, A. N., Jackson, J., Macklin, S. & Caulfield, T., Jan 1 2019, In : Molecular Omics. 15, 1, p. 59-66 8 p.

Research output: Contribution to journalArticle

2 Scopus citations

In vivo binding of a tau imaging probe, [11C]PBB3, in patients with progressive supranuclear palsy

Endo, H., Shimada, H., Sahara, N., Ono, M., Koga, S., Kitamura, S., Niwa, F., Hirano, S., Kimura, Y., Ichise, M., Shinotoh, H., Zhang, M. R., Kuwabara, S., Dickson, D. W., Toda, T., Suhara, T. & Higuchi, M., May 2019, In : Movement Disorders. 34, 5, p. 744-754 11 p.

Research output: Contribution to journalArticle

Open Access
3 Scopus citations

In Vivo Protein Complementation Demonstrates Presynaptic α-Synuclein Oligomerization and Age-Dependent Accumulation of 8–16-mer Oligomer Species

Kiechle, M., von Einem, B., Höfs, L., Voehringer, P., Grozdanov, V., Markx, D., Parlato, R., Wiesner, D., Mayer, B., Sakk, O., Baumann, B., Lukassen, S., Liss, B., Ekici, A. B., Ludolph, A. C., Walther, P., Ferger, B., McLean, P. J., Falkenburger, B. H., Weishaupt, J. H. & 1 others, Danzer, K. M., Nov 26 2019, In : Cell reports. 29, 9, p. 2862-2874.e9

Research output: Contribution to journalArticle

Open Access

Limbic-predominant age-related TDP-43 encephalopathy (LATE): Consensus working group report

Nelson, P. T., Dickson, D. W., Trojanowski, J. Q., Jack, C. R., Boyle, P. A., Arfanakis, K., Rademakers, R., Alafuzoff, I., Attems, J., Brayne, C., Coyle-Gilchrist, I. T. S., Chui, H. C., Fardo, D. W., Flanagan, M. E., Halliday, G., Hokkanen, S. R. K., Hunter, S., Jicha, G. A., Katsumata, Y., Kawas, C. H. & 15 others, Keene, C. D., Kovacs, G. G., Kukull, W. A., Levey, A. I., Makkinejad, N., Montine, T. J., Murayama, S., Murray, M. E., Nag, S., Rissman, R. A., Seeley, W. W., Sperling, R. A., White, C. L., Yu, L. & Schneider, J. A., Jun 1 2019, In : Brain. 142, 6, p. 1503-1527 25 p.

Research output: Contribution to journalReview article

Open Access
106 Scopus citations

Low prevalence of known pathogenic mutations in dominant PD genes: A Swedish multicenter study

Puschmann, A., Jiménez-Ferrer, I., Lundblad-Andersson, E., Mårtensson, E., Hansson, O., Odin, P., Widner, H., Brolin, K., Mzezewa, R., Kristensen, J., Soller, M., Rödström, E. Y., Ross, O. A., Toft, M., Breedveld, G. J., Bonifati, V., Brodin, L., Zettergren, A., Sydow, O., Linder, J. & 6 others, Wirdefeldt, K., Svenningsson, P., Nissbrandt, H., Belin, A. C., Forsgren, L. & Swanberg, M., Sep 2019, In : Parkinsonism and Related Disorders. 66, p. 158-165 8 p.

Research output: Contribution to journalArticle

Open Access
4 Scopus citations

Microglia in frontotemporal lobar degeneration with progranulin or C9ORF72 mutations

Sakae, N., Roemer, S. F., Bieniek, K. F., Murray, M. E., Baker, M. C., Kasanuki, K., Graff-Radford, N. R., Petrucelli, L., Van Blitterswijk, M., Rademakers, R. & Dickson, D. W., Sep 1 2019, In : Annals of Clinical and Translational Neurology. 6, 9, p. 1782-1796 15 p.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations

Miro1 Marks Parkinson's Disease Subset and Miro1 Reducer Rescues Neuron Loss in Parkinson's Models

Hsieh, C. H., Li, L., Vanhauwaert, R., Nguyen, K. T., Davis, M. D., Bu, G., Wszolek, Z. K. & Wang, X., Dec 3 2019, In : Cell Metabolism. 30, 6, p. 1131-1140.e7

Research output: Contribution to journalArticle

8 Scopus citations

Mixed Alzheimer’s and lewy-related pathology can cause corticobasal syndrome with visual hallucinations

Kasanuki, K., Koga, S., Dickson, D. W., Sato, K., Iseki, E., Ichimiya, Y. & Arai, H., 2019, In : Internal Medicine. 58, 12, 1 p.

Research output: Contribution to journalLetter

Open Access

Molecular dynamics simulations suggest a non-doublet decoding model of –1 frameshifting by tRNAser3

Caulfield, T., Coban, M., Tek, A. & Flores, S. C., Nov 2019, In : Biomolecules. 9, 11, 745.

Research output: Contribution to journalArticle

Open Access

Multisite study of the relationships between antemortem [ 11 C]PIB-PET Centiloid values and postmortem measures of Alzheimer's disease neuropathology

La Joie, R., Ayakta, N., Seeley, W. W., Borys, E., Boxer, A. L., DeCarli, C., Doré, V., Grinberg, L. T., Huang, E., Hwang, J. H., Ikonomovic, M. D., Jack, C., Jagust, W. J., Jin, L. W., Klunk, W. E., Kofler, J., Lesman-Segev, O. H., Lockhart, S. N., Lowe, V. J., Masters, C. L. & 15 others, Mathis, C. A., McLean, C. L., Miller, B. L., Mungas, D., O'Neil, J. P., Olichney, J. M., Parisi, J. E., Petersen, R. C., Rosen, H. J., Rowe, C. C., Spina, S., Vemuri, P., Villemagne, V. L., Murray, M. E. & Rabinovici, G. D., Feb 2019, In : Alzheimer's and Dementia. 15, 2, p. 205-216 12 p.

Research output: Contribution to journalArticle

16 Scopus citations

Neuroimaging correlates with neuropathologic schemes in neurodegenerative disease

Lowe, V. J., Lundt, E. S., Albertson, S. M., Przybelski, S. A., Senjem, M. L., Parisi, J. E., Kantarci, K., Boeve, B., Jones, D. T., Knopman, D., Jack, C. R., Dickson, D. W., Petersen, R. C. & Murray, M. E., Jul 2019, In : Alzheimer's and Dementia. 15, 7, p. 927-939 13 p.

Research output: Contribution to journalArticle

3 Scopus citations

Neuropathologic basis of frontotemporal dementia in progressive supranuclear palsy

Sakae, N., Josephs, K. A., Litvan, I., Murray, M. E., Duara, R., Uitti, R. J., Wszolek, Z. K., Graff-Radford, N. R. & Dickson, D. W., Nov 1 2019, In : Movement Disorders. 34, 11, p. 1655-1662 8 p.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations

No evidence for DNM3 as genetic modifier of age at onset in idiopathic Parkinson's disease

Berge-Seidl, V., Pihlstrøm, L., Wszolek, Z. K., Ross, O. A. & Toft, M., Feb 2019, In : Neurobiology of aging. 74, p. 236.e1-236.e5

Research output: Contribution to journalArticle

Nonlinear Z-score modeling for improved detection of cognitive abnormality

ARTFL/LEFFTDS consortium, Dec 2019, In : Alzheimer's and Dementia: Diagnosis, Assessment and Disease Monitoring. 11, p. 797-808 12 p.

Research output: Contribution to journalArticle

Open Access
2 Scopus citations

Ossified blood vessels in primary familial brain calcification elicit a neurotoxic astrocyte response

Zarb, Y., Weber-Stadlbauer, U., Kirschenbaum, D., Kindler, D. R., Richetto, J., Keller, D., Rademakers, R., Dickson, D. W., Pasch, A., Byzova, T., Nahar, K., Voigt, F. F., Helmchen, F., Boss, A., Aguzzi, A., Klohs, J. & Keller, A., Jan 1 2019, In : Brain. 142, 4, p. 885-902 18 p.

Research output: Contribution to journalArticle

Open Access
13 Scopus citations

Parkinson's disease in Nigeria: A review of published studies and recommendations for future research

Oluwole, O. G., Kuivaniemi, H., Carr, J. A., Ross, O. A., Olaogun, M. O. B., Bardien, S. & Komolafe, M. A., May 2019, In : Parkinsonism and Related Disorders. 62, p. 36-43 8 p.

Research output: Contribution to journalReview article

3 Scopus citations

Pathological, imaging and genetic characteristics support the existence of distinct TDP-43 types in non-FTLD brains

Josephs, K. A., Murray, M. E., Tosakulwong, N., Weigand, S. D., Serie, A. M., Perkerson, R. B., Matchett, B. J., Jack, C. R., Knopman, D. S., Petersen, R. C., Parisi, J. E., Petrucelli, L., Baker, M., Rademakers, R., Whitwell, J. L. & Dickson, D. W., Feb 11 2019, In : Acta neuropathologica. 137, 2, p. 227-238 12 p.

Research output: Contribution to journalArticle

10 Scopus citations

Perspectives on ethnic and racial disparities in Alzheimer's disease and related dementias: Update and areas of immediate need

International Society to Advance Alzheimer's Research and Treatment, Alzheimer's Association, Feb 2019, In : Alzheimer's and Dementia. 15, 2, p. 292-312 21 p.

Research output: Contribution to journalShort survey

26 Scopus citations

PET-detectable tau pathology correlates with long-term neuropsychiatric outcomes in patients with traumatic brain injury

Takahata, K., Kimura, Y., Sahara, N., Koga, S., Shimada, H., Ichise, M., Saito, F., Moriguchi, S., Kitamura, S., Kubota, M., Umeda, S., Niwa, F., Mizushima, J., Morimoto, Y., Funayama, M., Tabuchi, H., Bieniek, K. F., Kawamura, K., Zhang, M. R., Dickson, D. W. & 4 others, Mimura, M., Kato, M., Suhara, T. & Higuchi, M., Jan 1 2019, In : Brain. 142, 10, p. 3265-3279 15 p.

Research output: Contribution to journalArticle

Open Access
5 Scopus citations
5 Scopus citations

Preferential Disruption of Auditory Word Representations in Primary Progressive Aphasia with the Neuropathology of FTLD-TDP Type A

Mesulam, M. M., Nelson, M. J., Hyun, J., Rader, B., Hurley, R. S., Rademakers, R. V., Baker, M. C., Bigio, E. H. & Weintraub, S., Mar 1 2019, In : Cognitive and Behavioral Neurology. 32, 1, p. 46-53 8 p.

Research output: Contribution to journalArticle

3 Scopus citations

Progressive supranuclear palsy is not associated with neurogenic orthostatic hypotension

Van Gerpen, J. A., Al-Shaikh, R. H., Tipton, P. W., Wszolek, Z. K., Uitti, R. J., Ferman, T. J., Dickson, D. W., Benarroch, E. E., Singer, W., Cutsforth-Gregory, J. K., Heckman, M. G., Brushaber, D. E., Josephs, K. A., Low, P. A., Ahlskog, J. E. & Cheshire, W. P., Oct 1 2019, In : Neurology. 93, 14, p. E1339-E1347

Research output: Contribution to journalArticle

2 Scopus citations
3 Scopus citations

Protein informatics combined with multiple data sources enriches the clinical characterization of novel TRPV4 variant causing an intermediate skeletal dysplasia

Hines, S. L., Richter, J. E., Mohammad, A. N., Mahim, J., Atwal, P. S. & Caulfield, T., Jan 1 2019, In : Molecular Genetics and Genomic Medicine. e566.

Research output: Contribution to journalArticle

3 Scopus citations

rAAV-based brain slice culture models of Alzheimer’s and Parkinson’s disease inclusion pathologies

Croft, C. L., Cruz, P. E., Ryu, D. H., Ceballos-Diaz, C., Strang, K. H., Woody, B. M., Lin, W. L., Deture, M., Rodríguez-Lebrón, E., Dickson, D. W., Chakrabarty, P., Levites, Y., Giasson, B. I. & Golde, T. E., Mar 1 2019, In : Journal of Experimental Medicine. 216, 3, p. 539-555 17 p.

Research output: Contribution to journalArticle

Open Access
6 Scopus citations

Rates of lobar atrophy in asymptomatic MAPT mutation carriers

Chen, Q., Boeve, B. F., Senjem, M., Tosakulwong, N., Lesnick, T. G., Brushaber, D., Dheel, C., Fields, J., Forsberg, L., Gavrilova, R., Gearhart, D., Graff-Radford, J., Graff-Radford, N. R., Jack, C. R., Jones, D. T., Knopman, D. S., Kremers, W. K., Lapid, M., Rademakers, R., Syrjanen, J. & 4 others, Boxer, A. L., Rosen, H., Wszolek, Z. K. & Kantarci, K., 2019, In : Alzheimer's and Dementia: Translational Research and Clinical Interventions. 5, p. 338-346 9 p.

Research output: Contribution to journalArticle

Open Access
3 Scopus citations

Reply: LATE to the PART-y

Nelson, P. T., Dickson, D. W., Trojanowski, J. Q., Jack, C. R., Boyle, P. A., Arfanakis, K., Rademakers, R., Alafuzoff, I., Attems, J., Brayne, C., Coyle-Gilchrist, I. T. S., Fardo, D. W., Flanagan, M. E., Halliday, G., Hunter, S., Jicha, G. A., Katsumata, Y., Kawas, C. H., Dirk Keene, C., Kovacs, G. G. & 10 others, Kukull, W. A., Levey, A. I., Makkinejad, N., Montine, T. J., Murray, M. E., Nag, S., Seeley, W. W., Sperling, R. A., White, C. L. & Schneider, J. A., Sep 1 2019, In : Brain. 142, 9, p. 1-3 3 p.

Research output: Contribution to journalLetter

Revisiting the utility of TDP-43 immunoreactive (TDP-43-ir) pathology to classify FTLD-TDP subtypes

Nishihira, Y., Gefen, T., Mao, Q., Appin, C., Kohler, M., Walker, J., Rademakers, R., Rademaker, A., Rogalski, E., Weintraub, S., Geula, C., Mesulam, M. M. & Bigio, E. H., Jul 1 2019, In : Acta neuropathologica. 138, 1, p. 167-169 3 p.

Research output: Contribution to journalLetter

3 Scopus citations

RPS23RG1 Is Required for Synaptic Integrity and Rescues Alzheimer's Disease–Associated Cognitive Deficits

Zhao, D., Meng, J., Zhao, Y., Huo, Y., Liu, Y., Zheng, N., Zhang, M., Gao, Y., Chen, Z., Sun, H., Wang, X., Jing, C., Zhang, T., Zhang, X., Luo, H., Wang, X., Zhang, J., Liu, F. R., Li, Y., Bu, G. & 4 others, Wen, L., Huang, T. Y., Xu, H. & Zhang, Y. W., Aug 1 2019, In : Biological psychiatry. 86, 3, p. 171-184 14 p.

Research output: Contribution to journalArticle

3 Scopus citations

RPS25 is required for efficient RAN translation of C9orf72 and other neurodegenerative disease-associated nucleotide repeats

Yamada, S. B., Gendron, T. F., Niccoli, T., Genuth, N. R., Grosely, R., Shi, Y., Glaria, I., Kramer, N. J., Nakayama, L., Fang, S., Dinger, T. J. I., Thoeng, A., Rocha, G., Barna, M., Puglisi, J. D., Partridge, L., Ichida, J. K., Isaacs, A. M., Petrucelli, L. & Gitler, A. D., Sep 1 2019, In : Nature Neuroscience. 22, 9, p. 1383-1388 6 p.

Research output: Contribution to journalArticle

13 Scopus citations

Selective loss of cortical endothelial tight junction proteins during Alzheimer's disease progression

Yamazaki, Y., Shinohara, M., Shinohara, M., Yamazaki, A., Murray, M. E., Liesinger, A. M., Heckman, M. G., Lesser, E. R., Parisi, J. E., Petersen, R. C., Dickson, D. W., Kanekiyo, T. & Bu, G., Jan 1 2019, In : Brain. 142, 4, p. 1077-1092 16 p.

Research output: Contribution to journalArticle

13 Scopus citations

Selective Vulnerability of the Nucleus Basalis of Meynert among Neuropathologic Subtypes of Alzheimer Disease

Hanna Al-Shaikh, F. S., Duara, R., Crook, J. E., Lesser, E. R., Schaeverbeke, J., Hinkle, K. M., Ross, O. A., Ertekin-Taner, N., Pedraza, O., Dickson, D. W., Graff-Radford, N. R. & Murray, M. E., Jan 1 2019, (Accepted/In press) In : JAMA neurology.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations

Sensitivity and Specificity of Diagnostic Criteria for Progressive Supranuclear Palsy

Ali, F., Martin, P. R., Botha, H., Ahlskog, J. E., Bower, J. H., Masumoto, J. Y., Maraganore, D., Hassan, A., Eggers, S., Boeve, B. F., Knopman, D. S., Drubach, D., Petersen, R. C., Dunkley, E. D., van Gerpen, J., Uitti, R., Whitwell, J. L., Dickson, D. W. & Josephs, K. A., 2019, In : Movement Disorders. 34, 8, p. 1144-1153 10 p.

Research output: Contribution to journalArticle

22 Scopus citations

Serum neurofilament dynamics predicts neurodegeneration and clinical progression in presymptomatic Alzheimer’s disease

Dominantly Inherited Alzheimer Network, Feb 1 2019, In : Nature Medicine. 25, 2, p. 277-283 7 p.

Research output: Contribution to journalArticle

111 Scopus citations

Soluble TREM2 ameliorates pathological phenotypes by modulating microglial functions in an Alzheimer’s disease model

Zhong, L., Xu, Y., Zhuo, R., Wang, T., Wang, K., Huang, R., Wang, D., Gao, Y., Zhu, Y., Sheng, X., Chen, K., Wang, N., Zhu, L., Can, D., Marten, Y., Shinohara, M., Liu, C. C., Du, D., Sun, H., Wen, L. & 3 others, Xu, H., Bu, G. & Chen, X. F., Dec 1 2019, In : Nature communications. 10, 1, 1365.

Research output: Contribution to journalArticle

Open Access
29 Scopus citations

Spatiotemporal analysis for detection of pre-symptomatic shape changes in neurodegenerative diseases: Initial application to the GENFI cohort

Cury, C., Durrleman, S., Cash, D. M., Lorenzi, M., Nicholas, J. M., Bocchetta, M., van Swieten, J. C., Borroni, B., Galimberti, D., Masellis, M., Tartaglia, C., Rowe, J. B., Graff, C., Tagliavini, F., Frisoni, G. B., Laforce, R., Finger, E., de Mendonça, A., Sorbi, S., Ourselin, S. & 43 others, Rohrer, J. D., Modat, M., Andersson, C., Archetti, S., Arighi, A., Benussi, L., Black, S., Cosseddu, M., Fallstrm, M., Ferreira, C., Fenoglio, C., Fox, N., Freedman, M., Fumagalli, G., Gazzina, S., Ghidoni, R., Grisoli, M., Jelic, V., Jiskoot, L., Keren, R., Lombardi, G., Maruta, C., Meeter, L., van Minkelen, R., Nacmias, B., ijerstedt, L., Padovani, A., Panman, J., Pievani, M., Polito, C., Premi, E., Prioni, S., Rademakers, R., Redaelli, V., Rogaeva, E., Rossi, G., Rossor, M., Scarpini, E., Tang-Wai, D., Thonberg, H., Tiraboschi, P., Verdelho, A. & Warren, J., Mar 1 2019, In : NeuroImage. 188, p. 282-290 9 p.

Research output: Contribution to journalArticle

3 Scopus citations

Structure-based inhibitors halt prion-like seeding by Alzheimer's disease-and tauopathy-derived brain tissue samples

Seidler, P. M., Boyer, D. R., Murray, K. A., Yang, T. P., Bentzel, M., Sawaya, M. R., Rosenberg, G., Cascio, D., Williams, C. K., Newell, K. L., Ghetti, B., DeTure, M. A., Dickson, D. W., Vinters, H. V. & Eisenberg, D. S., Nov 1 2019, In : Journal of Biological Chemistry. 294, 44, p. 16451-16464 14 p.

Research output: Contribution to journalArticle

3 Scopus citations

Subventricular glial nodules in neurofibromatosis 1 with craniofacial dysmorphism and occipital meningoencephalocele

Hamano, T., Mutoh, T., Naiki, H., Shirafuji, N., Ikawa, M., Yamamura, O., Dickson, D. W., Aiki, S., Kuriyama, M. & Nakamoto, Y., Dec 2019, In : eNeurologicalSci. 17, 100213.

Research output: Contribution to journalArticle

Open Access

Systematic analysis of dark and camouflaged genes reveals disease-relevant genes hiding in plain sight

Ebbert, M. T. W., Jensen, T. D., Jansen-West, K., Sens, J. P., Reddy, J. S., Ridge, P. G., Kauwe, J. S. K., Belzil, V., Pregent, L., Carrasquillo, M. M., Keene, D., Larson, E., Crane, P., Asmann, Y. W., Ertekin-Taner, N., Younkin, S. G., Ross, O. A., Rademakers, R., Petrucelli, L. & Fryer, J. D., May 20 2019, In : Genome biology. 20, 1, 97.

Research output: Contribution to journalArticle

Open Access
8 Scopus citations

Tau exhibits unique seeding properties in globular glial tauopathy

Chung, D. E. C., Carlomagno, Y., Cook, C. N., Jansen-West, K., Daughrity, L., Lewis-Tuffin, L. J., Castanedes-Casey, M., DeTure, M., Dickson, D. W. & Petrucelli, L., Mar 7 2019, In : Acta Neuropathologica Communications. 7, 1, 1 p.

Research output: Contribution to journalArticle

Open Access
6 Scopus citations

Tau Subtypes of Alzheimer's Disease Determined in vivo Using Flortaucipir PET Imaging

Charil, A., Shcherbinin, S., Southekal, S., Devous, M. D., Mintun, M., Murray, M. E., Miller, B. B. & Schwarz, A. J., Jan 1 2019, In : Journal of Alzheimer's Disease. 71, 3, p. 1037-1048 12 p.

Research output: Contribution to journalArticle

Thalamo-cortical network hyperconnectivity in preclinical progranulin mutation carriers

Lee, S. E., Sias, A. C., Kosik, E. L., Flagan, T. M., Deng, J., Chu, S. A., Brown, J. A., Vidovszky, A. A., Ramos, E. M., Gorno-Tempini, M. L., Karydas, A. M., Coppola, G., Geschwind, D. H., Rademakers, R., Boeve, B. F., Boxer, A. L., Rosen, H. J., Miller, B. L. & Seeley, W. W., 2019, In : NeuroImage: Clinical. 22, 101751.

Research output: Contribution to journalArticle

Open Access
4 Scopus citations

The AMPK–Parkin axis negatively regulates necroptosis and tumorigenesis by inhibiting the necrosome

Lee, S. B., Kim, J. J., Han, S. A., Fan, Y., Guo, L. S., Aziz, K., Nowsheen, S., Kim, S. S., Park, S. Y., Luo, Q., Chung, J. O., Choi, S. I., Aziz, A., Yin, P., Tong, S. Y., Fiesel, F. C., Springer, W., Zhang, J. S. & Lou, Z., Aug 1 2019, In : Nature Cell Biology. 21, 8, p. 940-951 12 p.

Research output: Contribution to journalArticle

13 Scopus citations

The Hairpin Form of r(G 4 C 2 ) exp in c9ALS/FTD Is Repeat-Associated Non-ATG Translated and a Target for Bioactive Small Molecules

Wang, Z. F., Ursu, A., Childs-Disney, J. L., Guertler, R., Yang, W. Y., Bernat, V., Rzuczek, S. G., Fuerst, R., Zhang, Y., Gendron, T. D., Yildirim, I., Dwyer, B. G., Rice, J. E., Petrucelli, L. & Disney, M. D., Feb 21 2019, In : Cell Chemical Biology. 26, 2, p. 179-190.e12

Research output: Contribution to journalArticle

19 Scopus citations
18 Scopus citations

The influence of β-amyloid on [ 18 F]AV-1451 in semantic variant of primary progressive aphasia

Whitwell, J. L., Martin, P. R., Duffy, J. R., Clark, H., Machulda, M. M., Schwarz, C., Weigand, S. D., Sintini, I., Senjem, M. L., Taner, N., Botha, H., Utianski, R., Graff-Radford, J., Jones, D. T., Boeve, B. F., Knopman, D. S., Petersen, R. C., Jack, C. R. J., Lowe, V. & Josephs, K. A., Feb 12 2019, In : Neurology. 92, 7, p. e710-e722

Research output: Contribution to journalArticle

3 Scopus citations

The neuropathological diagnosis of Alzheimer's disease

Deture, M. A. & Dickson, D. W., Aug 2 2019, In : Molecular neurodegeneration. 14, 1, 32.

Research output: Contribution to journalReview article

Open Access
25 Scopus citations