Research Output

2020

Interaction between APOE genotype and diabetes in cognitive decline

Shinohara, M., Tashiro, Y., Suzuki, K., Fukumori, A., Bu, G. & Sato, N., 2020, In : Alzheimer's and Dementia: Diagnosis, Assessment and Disease Monitoring. 12, 1, e12006.

Research output: Contribution to journalArticle

Open Access

Large-scale proteomic analysis of Alzheimer’s disease brain and cerebrospinal fluid reveals early changes in energy metabolism associated with microglia and astrocyte activation

Johnson, E. C. B., Dammer, E. B., Duong, D. M., Ping, L., Zhou, M., Yin, L., Higginbotham, L. A., Guajardo, A., White, B., Troncoso, J. C., Thambisetty, M., Montine, T. J., Lee, E. B., Trojanowski, J. Q., Beach, T. G., Reiman, E. M., Haroutunian, V., Wang, M., Schadt, E., Zhang, B. & 13 others, Dickson, D. W., Ertekin-Taner, N., Golde, T. E., Petyuk, V. A., De Jager, P. L., Bennett, D. A., Wingo, T. S., Rangaraju, S., Hajjar, I., Shulman, J. M., Lah, J. J., Levey, A. I. & Seyfried, N. T., May 1 2020, In : Nature Medicine. 26, 5, p. 769-780 12 p.

Research output: Contribution to journalArticle

9 Scopus citations

Longitudinal amyloid-β PET in atypical Alzheimer's disease and frontotemporal lobar degeneration

Whitwell, J. L., Tosakulwong, N., Weigand, S. D., Graff-Radford, J., Duffy, J. R., Clark, H. M., Machulda, M. M., Botha, H., Utianski, R. L., Schwarz, C. G., Senjem, M. L., Strand, E., Ertekin-Taner, N., Jack, C. R., Lowe, V. J. & Josephs, K. A., Jan 1 2020, In : Journal of Alzheimer's Disease. 74, 1, p. 377-389 13 p.

Research output: Contribution to journalArticle

Loss of homeostatic microglial phenotype in CSF1R-related Leukoencephalopathy

Kempthorne, L., Yoon, H., Madore, C., Smith, S., Wszolek, Z. K., Rademakers, R., Kim, J., Butovsky, O. & Dickson, D. W., May 19 2020, In : Acta Neuropathologica Communications. 8, 1, 72.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations

Loss of TMEM106B leads to myelination deficits: implications for frontotemporal dementia treatment strategies

Zhou, X., Nicholson, A. M., Ren, Y., Brooks, M., Jiang, P., Zuberi, A., Phuoc, H. N., Perkerson, R. B., Matchett, B., Parsons, T. M., Finch, N. C. A., Lin, W., Qiao, W., Castanedes-Casey, M., Phillips, V., Librero, A. L., Asmann, Y., Bu, G., Murray, M. E., Lutz, C. & 2 others, Dickson, D. W. & Rademakers, R., Jun 1 2020, In : Brain : a journal of neurology. 143, 6, p. 1905-1919 15 p.

Research output: Contribution to journalArticle

LRP10 variants in progressive supranuclear palsy

Vergouw, L. J. M., Melhem, S., Donker Kaat, L., Chiu, W. Z., Kuipers, D. J. S., Breedveld, G., Boon, A. J. W., Wang, L. S., Naj, A. C., Mlynarksi, E., Cantwell, L., Quadri, M., Ross, O. A., Dickson, D. W., Schellenberg, G. D., van Swieten, J. C., Bonifati, V. & de Jong, F. J., Jan 1 2020, (Accepted/In press) In : Neurobiology of aging.

Research output: Contribution to journalArticle

MAPT haplotype–stratified GWAS reveals differential association for AD risk variants

Strickland, S. L., Reddy, J. S., Allen, M., N'songo, A., Burgess, J. D., Corda, M. M., Ballard, T., Wang, X., Carrasquillo, M. M., Biernacka, J. M., Jenkins, G. D., Mukherjee, S., Boehme, K., Crane, P., Kauwe, J. S. & Ertekin-Taner, N., Jul 1 2020, In : Alzheimer's and Dementia. 16, 7, p. 983-1002 20 p.

Research output: Contribution to journalArticle

Open Access

Microglial Homeostasis Requires Balanced CSF-1/CSF-2 Receptor Signaling

Chitu, V., Biundo, F., Shlager, G. G. L., Park, E. S., Wang, P., Gulinello, M. E., Gokhan, Ş., Ketchum, H. C., Saha, K., DeTure, M. A., Dickson, D. W., Wszolek, Z. K., Zheng, D., Croxford, A. L., Becher, B., Sun, D., Mehler, M. F. & Stanley, E. R., Mar 3 2020, In : Cell reports. 30, 9, p. 3004-3019.e5

Research output: Contribution to journalArticle

Open Access

Molecular inhibitor of QSOX1 suppresses tumor growth in vivo

Fifield, A. L., Hanavan, P. D., Faigel, D. O., Sergienko, E., Bobkov, A., Meurice, N., Petit, J. L., Polito, A., Caulfield, T. R., Castle, E. P., Copland, J. A., Mukhopadhyay, D., Pal, K., Dutta, S. K., Luo, H., Ho, T. H. & Lake, D. F., 2020, In : Molecular cancer therapeutics. 19, 1, p. 112-122 11 p.

Research output: Contribution to journalArticle

1 Scopus citations
Open Access

Nucleocytoplasmic Proteomic Analysis Uncovers eRF1 and Nonsense-Mediated Decay as Modifiers of ALS/FTD C9orf72 Toxicity

Ortega, J. A., Daley, E. L., Kour, S., Samani, M., Tellez, L., Smith, H. S., Hall, E. A., Esengul, Y. T., Tsai, Y. H., Gendron, T. F., Donnelly, C. J., Siddique, T., Savas, J. N., Pandey, U. B. & Kiskinis, E., Apr 8 2020, In : Neuron. 106, 1, p. 90-107.e13

Research output: Contribution to journalArticle

3 Scopus citations

Pathology-Proven Corticobasal Degeneration Presenting as Richardson's Syndrome

Bayram, E., Dickson, D. W., Reich, S. G. & Litvan, I., Apr 1 2020, In : Movement Disorders Clinical Practice. 7, 3, p. 267-272 6 p.

Research output: Contribution to journalArticle

Pick’s disease: clinicopathologic characterization of 21 cases

Choudhury, P., Scharf, E. L., Paolini, M. A., Graff-Radford, J., Alden, E. C., Machulda, M. M., Jones, D. T., Fields, J. A., Murray, M. E., Graff-Radford, N. R., Constantopoulos, E., Reichard, R. R., Knopman, D. S., Duffy, J. R., Dickson, D. W., Parisi, J. E., Josephs, K. A., Petersen, R. C. & Boeve, B. F., 2020, (Accepted/In press) In : Journal of Neurology.

Research output: Contribution to journalArticle

4 Scopus citations

Posttranslational Modifications Mediate the Structural Diversity of Tauopathy Strains

Arakhamia, T., Lee, C. E., Carlomagno, Y., Duong, D. M., Kundinger, S. R., Wang, K., Williams, D., DeTure, M., Dickson, D. W., Cook, C. N., Seyfried, N. T., Petrucelli, L. & Fitzpatrick, A. W. P., Feb 20 2020, In : Cell. 180, 4, p. 633-644.e12

Research output: Contribution to journalArticle

12 Scopus citations

Premature termination codon readthrough upregulates progranulin expression and improves lysosomal function in preclinical models of GRN deficiency

Frew, J., Baradaran-Heravi, A., Balgi, A. D., Wu, X., Yan, T. D., Arns, S., Shidmoossavee, F. S., Tan, J., Jaquith, J. B., Jansen-West, K. R., Lynn, F. C., Gao, F. B., Petrucelli, L., Feldman, H. H., MacKenzie, I. R., Roberge, M. & Nygaard, H. B., Mar 16 2020, In : Molecular neurodegeneration. 15, 1, 21.

Research output: Contribution to journalArticle

Open Access

Prevalence of GBA p.K198E mutation in Colombian and Hispanic populations

Tipton, P. W., Soto-Beasley, A. I., Walton, R. L., Soler-Rangel, S., Romero-Osorio, Ó., Díaz, C., Moreno-López, C. L., Ross, O. A., Wszolek, Z. K. & Cerquera-Cleves, C., Apr 2020, In : Parkinsonism and Related Disorders. 73, p. 16-18 3 p.

Research output: Contribution to journalLetter

Prominent amyloid plaque pathology and cerebral amyloid angiopathy in APP V717I (London) carrier - Phenotypic variability in autosomal dominant Alzheimer's disease

Lloyd, G. M., Trejo-Lopez, J. A., Xia, Y., McFarland, K. N., Lincoln, S. J., Ertekin-Taner, N., Giasson, B. I., Yachnis, A. T. & Prokop, S., Mar 12 2020, In : Acta Neuropathologica Communications. 8, 1, 31.

Research output: Contribution to journalArticle

Open Access

Publisher Correction: Exome sequencing in amyotrophic lateral sclerosis implicates a novel gene, DNAJC7, encoding a heat-shock protein (Nature Neuroscience, (2019), 22, 12, (1966-1974), 10.1038/s41593-019-0530-0)

ALSGENS Consortium, FALS Consortium, Project MinE Consortium & CReATe Consortium, Feb 1 2020, In : Nature Neuroscience. 23, 2, 1 p.

Research output: Contribution to journalComment/debate

Open Access
1 Scopus citations

Reduced C9ORF72 function exacerbates gain of toxicity from ALS/FTD-causing repeat expansion in C9orf72

Zhu, Q., Jiang, J., Gendron, T. F., McAlonis-Downes, M., Jiang, L., Taylor, A., Diaz Garcia, S., Ghosh Dastidar, S., Rodriguez, M. J., King, P., Zhang, Y., La Spada, A. R., Xu, H., Petrucelli, L., Ravits, J., Da Cruz, S., Lagier-Tourenne, C. & Cleveland, D. W., May 1 2020, In : Nature Neuroscience. 23, 5, p. 615-624 10 p.

Research output: Contribution to journalArticle

6 Scopus citations

Screening of the glucocerebrosidase (GBA) gene in South Africans of African ancestry with Parkinson's disease

Mahungu, A. C., Anderson, D. G., Rossouw, A. C., van Coller, R., Carr, J. A., Ross, O. A. & Bardien, S., Apr 2020, In : Neurobiology of aging. 88, p. 156.e11-156.e14

Research output: Contribution to journalArticle

1 Scopus citations

Targeted next-generation sequencing identifies novel variants in candidate genes for Parkinson's disease in Black South African and Nigerian patients

Oluwole, O. G., Kuivaniemi, H., Abrahams, S., Haylett, W. L., Vorster, A. A., Van Heerden, C. J., Kenyon, C. P., Tabb, D. L., Fawale, M. B., Sunmonu, T. A., Ajose, A., Olaogun, M. O., Rossouw, A. C., Van Hillegondsberg, L. S., Carr, J., Ross, O. A., Komolafe, M. A., Tromp, G. & Bardien, S., Feb 4 2020, In : BMC medical genetics. 21, 1, 23.

Research output: Contribution to journalArticle

Open Access
3 Scopus citations

Tau-positron emission tomography correlates with neuropathology findings

Lowe, V. J., Lundt, E. S., Albertson, S. M., Min, H. K., Fang, P., Przybelski, S. A., Senjem, M. L., Schwarz, C. G., Kantarci, K., Boeve, B., Jones, D. T., Reichard, R. R., Tranovich, J. F., Hanna Al-Shaikh, F. S., Knopman, D. S., Jack, C. R., Dickson, D. W., Petersen, R. C. & Murray, M. E., Mar 1 2020, In : Alzheimer's and Dementia. 16, 3, p. 561-571 11 p.

Research output: Contribution to journalArticle

4 Scopus citations

The longitudinal evaluation of familial frontotemporal dementia subjects protocol: Framework and methodology

on Behalf of the LEFFTDS Consortium, Jan 1 2020, In : Alzheimer's and Dementia. 16, 1, p. 22-36 15 p.

Research output: Contribution to journalArticle

Open Access
4 Scopus citations

Traffic jam at the nuclear pore: All roads lead to nucleocytoplasmic transport defects in ALS/FTD

Fallini, C., Khalil, B., Smith, C. L. & Rossoll, W., Jul 2020, In : Neurobiology of Disease. 140, 104835.

Research output: Contribution to journalReview article

Open Access

Trajectory of lobar atrophy in asymptomatic and symptomatic GRN mutation carriers: a longitudinal MRI study

Chen, Q., Boeve, B. F., Senjem, M., Tosakulwong, N., Lesnick, T., Brushaber, D., Dheel, C., Fields, J., Forsberg, L., Gavrilova, R., Gearhart, D., Graff-Radford, J., Graff-Radford, N., Jack, C. R., Jones, D., Knopman, D., Kremers, W. K., Lapid, M., Rademakers, R., Ramos, E. M. & 5 others, Syrjanen, J., Boxer, A. L., Rosen, H., Wszolek, Z. K. & Kantarci, K., Apr 2020, In : Neurobiology of aging. 88, p. 42-50 9 p.

Research output: Contribution to journalArticle

1 Scopus citations

Utility of the global CDR® plus NACC FTLD rating and development of scoring rules: Data from the ARTFL/LEFFTDS Consortium

Miyagawa, T., Brushaber, D., Syrjanen, J., Kremers, W., Fields, J., Forsberg, L. K., Heuer, H. W., Knopman, D., Kornak, J., Boxer, A., Rosen, H. J., Boeve, B. F., Appleby, B., Bordelon, Y., Bove, J., Brannelly, P., Caso, C., Coppola, G., Dever, R., Dheel, C. & 65 others, Dickerson, B., Dickinson, S., Dominguez, S., Domoto-Reilly, K., Faber, K., Ferrell, J., Fishman, A., Fong, J., Foroud, T., Gavrilova, R., Gearhart, D., Ghazanfari, B., Ghoshal, N., Goldman, J. S., Graff-Radford, J., Graff-Radford, N., Grant, I., Grossman, M., Haley, D., Hsiung, R., Huey, E., Irwin, D., Jones, D., Jones, L., Kantarci, K., Karydas, A., Kaufer, D., Kerwin, D., Kraft, R., Kramer, J., Kukull, W., Litvan, I., Lucente, D., Lungu, C., Mackenzie, I., Maldonado, M., Manoochehri, M., McGinnis, S., McKinley, E., Mendez, M. F., Miller, B., Multani, N., Onyike, C., Padmanabhan, J., Pantelyat, A., Pearlman, R., Petrucelli, L., Potter, M., Rademakers, R. V., Ramos, E. M., Rankin, K., Rascovsky, K., Roberson, E. D., Rogalski, E., Sengdy, P., Shaw, L., Tartaglia, M. C., Tatton, N., Taylor, J., Toga, A., Trojanowski, J. Q., Wang, P., Weintraub, S., Wong, B. & Wszolek, Z. K., Jan 1 2020, In : Alzheimer's and Dementia. 16, 1, p. 106-117 12 p.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations

Validation of the movement disorder society criteria for the diagnosis of 4-repeat tauopathies

for the Movement Disorder Society–Endorsed Progressive Supranuclear Palsy Study Group, Jan 1 2020, In : Movement Disorders. 35, 1, p. 171-176 6 p.

Research output: Contribution to journalArticle

4 Scopus citations

α-Synuclein filaments from transgenic mouse and human synucleinopathy-containing brains are major seed-competent species

Morgan, S. A., Lavenir, I., Fan, J., Masuda-Suzukake, M., Passarella, D., DeTure, M. A., Dickson, D. W., Bernardino Ghetti, X. & Goedert, M., May 8 2020, In : Journal of Biological Chemistry. 295, 19, p. 6652-6664 13 p.

Research output: Contribution to journalArticle

Open Access

β-Amyloid PET and neuropathology in dementia with Lewy bodies

Kantarci, K., Lowe, V. J., Chen, Q., Przybelski, S. A., Lesnick, T. G., Schwarz, C. G., Senjem, M. L., Gunter, J. L., Jack, C. R., Graff-Radford, J., Jones, D. T., Knopman, D. S., Graff-Radford, N., Ferman, T. J., Parisi, J. E., Dickson, D. W., Petersen, R. C., Boeve, B. F. & Murray, M. E., Jan 21 2020, In : Neurology. 94, 3, p. e282-e291

Research output: Contribution to journalArticle

Open Access
2019

5-HT3 antagonist ondansetron increases apoE secretion by modulating the LXR-ABCA1 pathway

Shinohara, M., Shinohara, M., Zhao, J., Fu, Y., Liu, C. C., Kanekiyo, T. & Bu, G., Mar 2 2019, In : International journal of molecular sciences. 20, 6, 1488.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations

ABCA7 haplodeficiency disturbs microglial immune responses in the mouse brain

Aikawa, T., Ren, Y., Yamazaki, Y., Tachibana, M., Johnson, M. R., Anderson, C. T., Martens, Y. A., Holm, M. L., Asmann, Y. W., Saito, T., Saido, T. C., Fitzgerald, M. L., Bu, G. & Kanekiyo, T., 2019, In : Proceedings of the National Academy of Sciences of the United States of America. 116, 47, p. 23790-23796 7 p.

Research output: Contribution to journalArticle

1 Scopus citations

Aberrant deposition of stress granule-resident proteins linked to C9orf72-associated TDP-43 proteinopathy

Chew, J., Cook, C., Gendron, T. F., Jansen-West, K., Del Rosso, G., Daughrity, L. M., Castanedes-Casey, M., Kurti, A., Stankowski, J. N., Disney, M. D., Rothstein, J. D., Dickson, D. W., Fryer, J. D., Zhang, Y. J. & Petrucelli, L., Feb 15 2019, In : Molecular neurodegeneration. 14, 1, 9.

Research output: Contribution to journalArticle

14 Scopus citations

A brain somatic RHEB doublet mutation causes focal cortical dysplasia type II

Zhao, S., Li, Z., Zhang, M., Zhang, L., Zheng, H., Ning, J., Wang, Y., Wang, F., Zhang, X., Gan, H., Wang, Y., Zhang, X., Luo, H., Bu, G., Xu, H., Yao, Y. & Zhang, Y. W., Jul 1 2019, In : Experimental and Molecular Medicine. 51, 7, 84.

Research output: Contribution to journalArticle

Open Access
3 Scopus citations

A comprehensive screening of copy number variability in dementia with Lewy bodies

Kun-Rodrigues, C., Orme, T., Carmona, S., Hernandez, D. G., Ross, O. A., Eicher, J. D., Shepherd, C., Parkkinen, L., Darwent, L., Heckman, M. G., Scholz, S. W., Troncoso, J. C., Pletnikova, O., Dawson, T., Rosenthal, L., Ansorge, O., Clarimon, J., Lleo, A., Morenas-Rodriguez, E., Clark, L. & 48 others, Honig, L. S., Marder, K., Lemstra, A., Rogaeva, E., St. George-Hyslop, P., Londos, E., Zetterberg, H., Barber, I., Braae, A., Brown, K., Morgan, K., Troakes, C., Al-Sarraj, S., Lashley, T., Holton, J., Compta, Y., Van Deerlin, V., Serrano, G. E., Beach, T. G., Lesage, S., Galasko, D., Masliah, E., Santana, I., Pastor, P., Diez-Fairen, M., Aguilar, M., Tienari, P. J., Myllykangas, L., Oinas, M., Revesz, T., Lees, A., Boeve, B. F., Petersen, R. C., Ferman, T. J., Escott-Price, V., Graff-Radford, N., Cairns, N. J., Morris, J. C., Pickering-Brown, S., Mann, D., Halliday, G. M., Hardy, J., Trojanowski, J. Q., Dickson, D. W., Singleton, A., Stone, D. J., Guerreiro, R. & Bras, J., Mar 2019, In : Neurobiology of aging. 75, p. 223.e1-223.e10

Research output: Contribution to journalArticle

7 Scopus citations

ADAR2 mislocalization and widespread RNA editing aberrations in C9orf72-mediated ALS/FTD

Moore, S., Alsop, E., Lorenzini, I., Starr, A., Rabichow, B. E., Mendez, E., Levy, J. L., Burciu, C., Reiman, R., Chew, J., Belzil, V. V., W. Dickson, D., Robertson, J., Staats, K. A., Ichida, J. K., Petrucelli, L., Van Keuren-Jensen, K. & Sattler, R., Jan 1 2019, In : Acta neuropathologica.

Research output: Contribution to journalArticle

10 Scopus citations

Akt Phosphorylates NQO1 and Triggers its Degradation, Abolishing Its Antioxidative Activities in Parkinson's Disease

Luo, S., Kang, S. S., Wang, Z. H., Liu, X., Day, J. X., Wu, Z., Peng, J., Xiang, D., Springer, W. & Ye, K., Sep 11 2019, In : The Journal of neuroscience : the official journal of the Society for Neuroscience. 39, 37, p. 7291-7305 15 p.

Research output: Contribution to journalArticle

5 Scopus citations

A nonsynonymous mutation in PLCG2 reduces the risk of Alzheimer’s disease, dementia with Lewy bodies and frontotemporal dementia, and increases the likelihood of longevity

DESGESCO (Dementia Genetics Spanish Consortium), EADB (Alzheimer Disease European DNA biobank), EADB (Alzheimer Disease European DNA biobank), IFGC (International FTD-Genomics Consortium), IPDGC (The International Parkinson Disease Genomics Consortium), IPDGC (The International Parkinson Disease Genomics Consortium), RiMod-FTD (Risk and Modifying factors in Fronto-Temporal Dementia), Netherlands Brain Bank (NBB) & The GIFT (Genetic Investigation in Frontotemporal Dementia and Alzheimer’s Disease) Study Group, Aug 1 2019, In : Acta neuropathologica. 138, 2, p. 237-250 14 p.

Research output: Contribution to journalArticle

Open Access
15 Scopus citations

Antemortem volume loss mirrors TDP-43 staging in older adults with non-frontotemporal lobar degeneration

Bejanin, A., Murray, M. E., Martin, P., Botha, H., Tosakulwong, N., Schwarz, C. G., Senjem, M. L., Chételat, G., Kantarci, K., Jack, C. R., Boeve, B. F., Knopman, D. S., Petersen, R. C., Giannini, C., Parisi, J. E., Dickson, D. W., Whitwell, J. L. & Josephs, K. A., Nov 1 2019, In : Brain. 142, 11, p. 3621-3635 15 p.

Research output: Contribution to journalArticle

4 Scopus citations

ApoE-2 Brain-Targeted Gene Therapy Through Transferrin and Penetratin Tagged Liposomal Nanoparticles

dos Santos Rodrigues, B., Kanekiyo, T. & Singh, J., Nov 1 2019, In : Pharmaceutical research. 36, 11, 161.

Research output: Contribution to journalArticle

2 Scopus citations

APOE4-mediated amyloid-β pathology depends on its neuronal receptor LRP1

Tachibana, M., Holm, M. L., Liu, C. C., Shinohara, M., Aikawa, T., Oue, H., Yamazaki, Y., Martens, Y. A., Murray, M. E., Sullivan, P. M., Weyer, K., Glerup, S., Dickson, D. W., Bu, G. & Kanekiyo, T., Mar 2019, In : Journal of Clinical Investigation. 129, 3, p. 1272-1277 6 p.

Research output: Contribution to journalArticle

14 Scopus citations

Apolipoprotein E and Alzheimer disease: pathobiology and targeting strategies

Yamazaki, Y., Zhao, N., Caulfield, T., Liu, C-C. & Bu, G. D., Sep 1 2019, In : Nature Reviews Neurology. 15, 9, p. 501-518 18 p.

Research output: Contribution to journalReview article

45 Scopus citations

Association of MAPT H1 subhaplotypes with neuropathology of lewy body disease

Heckman, M. G., Kasanuki, K., Brennan, R. R., Labbé, C., Vargas, E. R., Soto, A. I., Murray, M. E., Koga, S., Dickson, D. W. & Ross, O. A., Sep 1 2019, In : Movement Disorders. 34, 9, p. 1325-1332 8 p.

Research output: Contribution to journalArticle

3 Scopus citations

Association of mapt subhaplotypes with risk of progressive supranuclear palsy and severity of tau pathology

Heckman, M. G., Brennan, R. R., Labbé, C., Soto, A. I., Koga, S., Deture, M. A., Murray, M. E., Petersen, R. C., Boeve, B. F., Van Gerpen, J. A., Uitti, R. J., Wszolek, Z. K., Rademakers, R., Dickson, D. W. & Ross, O. A., Jun 2019, In : JAMA neurology. 76, 6, p. 710-717 8 p.

Research output: Contribution to journalArticle

7 Scopus citations

Author Correction: Genetic meta-analysis of diagnosed Alzheimer’s disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing (Nature Genetics, (2019), 51, 3, (414-430), 10.1038/s41588-019-0358-2)

Alzheimer Disease Genetics Consortium (ADGC), The European Alzheimer’s Disease Initiative (EADI), Cohorts for Heart and Aging Research in Genomic Epidemiology Consortium (CHARGE) & Genetic and Environmental Risk in AD/Defining Genetic, Polygenic and Environmental Risk for Alzheimer’s Disease Consortium (GERAD/PERADES), Sep 1 2019, In : Nature Genetics. 51, 9, p. 1423-1424 2 p.

Research output: Contribution to journalComment/debate

Open Access
2 Scopus citations

Author Correction: Soluble TREM2 ameliorates pathological phenotypes by modulating microglial functions in an Alzheimer’s disease model (Nature Communications, (2019), 10, 1, (1365), 10.1038/s41467-019-09118-9)

Zhong, L., Xu, Y., Zhuo, R., Wang, T., Wang, K., Huang, R., Wang, D., Gao, Y., Zhu, Y., Sheng, X., Chen, K., Wang, N., Zhu, L., Can, D., Marten, Y., Shinohara, M., Liu, C. C., Du, D., Sun, H., Wen, L. & 3 others, Xu, H., Bu, G. & Chen, X. F., Dec 1 2019, In : Nature communications. 10, 1, 2923.

Research output: Contribution to journalComment/debate

Open Access
1 Scopus citations
5 Scopus citations

Brain MR Spectroscopy Changes Precede Frontotemporal Lobar Degeneration Phenoconversion in Mapt Mutation Carriers

Chen, Q., Boeve, B. F., Tosakulwong, N., Lesnick, T., Brushaber, D., Dheel, C., Fields, J., Forsberg, L., Gavrilova, R., Gearhart, D., Haley, D., Gunter, J. L., Graff-Radford, J., Jones, D., Knopman, D., Graff-Radford, N., Kraft, R., Lapid, M., Rademakers, R., Wszolek, Z. K. & 3 others, Rosen, H., Boxer, A. L. & Kantarci, K., Sep 1 2019, In : Journal of Neuroimaging. 29, 5, p. 624-629 6 p.

Research output: Contribution to journalArticle

2 Scopus citations