Research Output

1995

Correlations of synaptic and pathological markers with cognition of the elderly

Dickson, D. W., Crystal, H. A., Bevona, C., Honer, W., Vincent, I. & Davies, P., 1995, In : Neurobiology of aging. 16, 3, p. 285-298 14 p.

Research output: Contribution to journalArticle

338 Scopus citations

Cryptococcus neoformans survive and replicate in human microglia

Lee, S. C., Kress, Y., Zhao, M. L., Dickson, D. W. & Casadevall, A., 1995, In : Laboratory Investigation. 73, 6, p. 871-879 9 p.

Research output: Contribution to journalArticle

64 Scopus citations

Electron microscopic localization of ATPase activity in tobacco cells infected by tobacco etch potyvirus and tobacco mosaic virus

Chen, S., Das, P., Abdel Ghaffar, M. H. & Hari, V., Jan 1 1995, In : Archives of Virology. 140, 1, p. 173-178 6 p.

Research output: Contribution to journalArticle

Evidence that Aβ42 is the real culprit in alzheimer's disease

Younkin, S. G., Mar 1995, In : Annals of neurology. 37, 3, p. 287-288 2 p.

Research output: Contribution to journalEditorial

289 Scopus citations

Fasciculin 2 binds to the peripheral site on acetylcholinesterase and inhibits substrate hydrolysis by slowing a step involving proton transfer during enzyme acylation

Eastman, J., Wilson, E. J., Cervenansky, C. & Rosenberry, T. L., Jan 1 1995, In : Journal of Biological Chemistry. 270, 34, p. 19694-19701 8 p.

Research output: Contribution to journalArticle

95 Scopus citations

Heterogeneity of melanized neurons expressing neurotensin receptor messenger RNA in the substantia nigra and the nucleus paranigralis of control and Parkinson's disease brain

Yamada, M., Yamada, M. & Richelson, E., Jan 1995, In : Neuroscience. 64, 2, p. 405-417 13 p.

Research output: Contribution to journalArticle

25 Scopus citations

In Human Fetal Astrocytes Exposure to Interleukin‐1β Stimulates Acquisition of the GD3+ Phenotype and Inhibits Cell Division

Lee, S. C., Liu, W., Dickson, D. W. & Brosnan, C. F., Apr 1995, In : Journal of neurochemistry. 64, 4, p. 1800-1807 8 p.

Research output: Contribution to journalArticle

18 Scopus citations

Low density lipoprotein receptor-related protein mediates apolipoprotein E-dependent neurite outgrowth in a central nervous system-derived neuronal cell line

Holtzman, D. M., Pitas, R. E., Kilbridge, J., Nathan, B., Mahley, R. W., Bu, G. & Schwartz, A. L., Oct 10 1995, In : Proceedings of the National Academy of Sciences of the United States of America. 92, 21, p. 9480-9484 5 p.

Research output: Contribution to journalArticle

315 Scopus citations
53 Scopus citations

Pharmacological and biochemical profiles of unique neurotensin 8-13 analogs exhibiting species selectivity, stereoselectivity, and superagonism

Cusack, B., McCormick, D. J., Pang, Y. P., Souder, T., Garcia, R., Fauq, A. & Richelson, E., 1995, In : Journal of Biological Chemistry. 270, 31, p. 18359-18366 8 p.

Research output: Contribution to journalArticle

50 Scopus citations

Pharmacological characterization of SR 48692 sensitive neurotensin receptor in human pancreatic cancer cells, MIA Paca-2

Yamada, M., Ohata, H., Momose, K., Yamada, M. & Richelson, E., 1995, In : Research Communications in Molecular Pathology and Pharmacology. 90, 1, p. 37-47 11 p.

Research output: Contribution to journalArticle

26 Scopus citations

Protein Denaturation by Addition and Removal of Acetonitrile: Application to Tryptic Digestion of Acetylcholinesterase

Haas, R. & Rosenberry, T. L., Jan 1995, In : Analytical Biochemistry. 224, 1, p. 425-427 3 p.

Research output: Contribution to journalArticle

11 Scopus citations

Regulation of daily rhythm of body temperature by neurotensin receptor in rats

Yamada, M., Cho, T., Coleman, N. J., Yamada, M. & Richelson, E., 1995, In : Research Communications in Molecular Pathology and Pharmacology. 87, 3, p. 323-332 10 p.

Research output: Contribution to journalArticle

10 Scopus citations

Regulation of neurotensin receptor mRNA expression by neuroleptics in the rat midbrain dopaminergic neurons

Cho, T., Yamada, M., Yamada, M. & Richelson, E., 1995, In : Research Communications in Biological Psychology, Psychiatry and Neurosciences. 20, 1-2, p. 1-5 5 p.

Research output: Contribution to journalArticle

Regulation of neurotensin receptor mRNA expression by the receptor antagonist SR 48692 in the rat midbrain dopaminergic neurons

Yamada, M., Bolden-Watson, C., Watson, M. A., Cho, T., Coleman, N. J., Yamada, M. & Richelson, E., 1995, In : Molecular Brain Research. 33, 2, p. 343-346 4 p.

Research output: Contribution to journalArticle

11 Scopus citations

Serum anticholinergic activity in hospitalized older persons with delirium: A preliminary study

Mach, J. R., Dysken, M. W., Kuskowski, M., Richelson, E., Holden, L. & Jilk, K. M., 1995, In : Journal of the American Geriatrics Society. 43, 5, p. 491-495 5 p.

Research output: Contribution to journalArticle

98 Scopus citations

Sites Within the 39-kDa Protein Important for Regulating Ligand Binding to the Low-Density Lipoprotein Receptor-Related Protein

Warshawsky, I., Bu, G. & Schwartz, A. L., Jan 1 1995, In : Biochemistry. 34, 10, p. 3404-3415 12 p.

Research output: Contribution to journalArticle

33 Scopus citations

Synthesis of partial nonpeptidic peptide mimetics as potential neurotensin agonists and antagonists

Kozikowski, A. P., Dodd, D. S., Zaidi, J., Pang, Y. P., Cusack, B. & Richelson, E., Jan 1 1995, In : Journal of the Chemical Society, Perkin Transactions 1. 12, p. 1615-1621 7 p.

Research output: Contribution to journalArticle

16 Scopus citations

The carboxy terminus of tissue factor pathway inhibitor is required for interacting with hepatoma cells in vitro and in vivo

Warshawsky, I., Bu, G., Mast, A., Saffitz, J. E., Broze, G. J. & Schwartz, A. L., Apr 1995, In : Journal of Clinical Investigation. 95, 4, p. 1773-1781 9 p.

Research output: Contribution to journalArticle

Open Access
65 Scopus citations

The Distribution and Biochemical Properties of a Cdc2‐Related Kinase, KKIALRE, in Normal and Alzheimer Brains

Yen, SH. H., Kenessey, A., Lee, S. C. & Dickson, D. W., Dec 1995, In : Journal of neurochemistry. 65, 6, p. 2577-2584 8 p.

Research output: Contribution to journalArticle

30 Scopus citations

The structure of the presenilin 1 (S182) gene and identification of six novel mutations in early onset AD families

The Alzheimer’s Disease Collaborative Group, Oct 1995, In : Nature Genetics. 11, 2, p. 219-222 4 p.

Research output: Contribution to journalArticle

433 Scopus citations

Two receptor systems are involved in the plasma clearance of tissue factor pathway inhibitor in vivo

Narita, M., Bu, G., Olins, G. M., Higuchi, D. A., Herz, J., Broze, G. J. & Schwartz, A. L., Jan 1 1995, In : Journal of Biological Chemistry. 270, 42, p. 24800-24804 5 p.

Research output: Contribution to journalArticle

74 Scopus citations

Two receptor systems are involved in the plasma clearance of tissue-type plasminogen activator (t-PA) in vivo

Narita, M., Bu, G., Herz, J. & Schwarte, A. L., Aug 1995, In : Journal of Clinical Investigation. 96, 2, p. 1164-1168 5 p.

Research output: Contribution to journalArticle

Open Access
71 Scopus citations

Uptake of exogenous sn-1-acyl-2-lyso-phosphatidylinositol into HeLa S3 cells: Reacylation on the cell surface and metabolism to glucosaminyl(acyl)phosphatidylinositol

Wongkajornsilp, A. & Rosenberry, T. L., Apr 21 1995, In : Journal of Biological Chemistry. 270, 16, p. 9147-9153 7 p.

Research output: Contribution to journalArticle

9 Scopus citations
1996

Accumulation of β-amyloid fibrils in pancreas of transgenic mice

Kawarabayashi, T., Shoji, M., Sato, M., Sasaki, A., Ho, L., Eckman, C. B., Prada, C. M., Younkin, S. G., Kobayashi, T., Tada, N., Matsubara, E., Iizuka, T., Harigaya, Y., Kasai, K. & Hirai, S., Jan 1 1996, In : Neurobiology of aging. 17, 2, p. 215-222 8 p.

Research output: Contribution to journalArticle

65 Scopus citations

Amyloids β40 and β42 are generated intracellularly in cultured human neurons and their secretion increases with maturation

Turner, R. S., Suzuki, N., Chyung, A. S. C., Younkin, S. G. & Lee, V. M. Y., Apr 12 1996, In : Journal of Biological Chemistry. 271, 15, p. 8966-8970 5 p.

Research output: Contribution to journalArticle

Open Access
158 Scopus citations

Apolipoprotein E-containing high density lipoprotein promotes neurite outgrowth and is a ligand for the low density lipoprotein receptor-related protein

Fagan, A. M., Bu, G., Sun, Y., Daugherty, A. & Holtzman, D. M., 1996, In : Journal of Biological Chemistry. 271, 47, p. 30121-30125 5 p.

Research output: Contribution to journalArticle

181 Scopus citations

Associations of status and change measures of neuropsychological function with pathologic changes in elderly, originally nondemented subjects

Crystal, H. A., Dickson, D., Sliwinski, M., Masur, D., Blau, A. & Lipton, R. B., Jan 1996, In : Archives of neurology. 53, 1, p. 82-87 6 p.

Research output: Contribution to journalArticle

27 Scopus citations
30 Scopus citations

Consensus guidelines for the clinical and pathologic diagnosis of dementia with Lewy bodies (DLB): Report of the consortium on DLB international workshop

McKeith, I. G., Galasko, D., Kosaka, K., Perry, E. K., Dickson, D. W., Hansen, L. A., Salmon, D. P., Lowe, J., Mirra, S. S., Byrne, E. J., Lennox, G., Quinn, N. P., Edwardson, J. A., Ince, P. G., Bergeron, C., Burns, A., Miller, B. L., Lovestone, S., Collerton, D., Jansen, E. N. H. & 5 others, Ballard, C., De Vos, R. A. I., Wilcock, G. K., Jellinger, K. A. & Perry, R. H., Nov 1996, In : Neurology. 47, 5, p. 1113-1124 12 p.

Research output: Contribution to journalReview article

3431 Scopus citations
19 Scopus citations

Correlative memory deficits, Aβ elevation, and amyloid plaques in transgenic mice

Hsiao, K., Chapman, P., Nilsen, S., Eckman, C., Harigaya, Y., Younkin, S., Yang, F. & Cole, G., Oct 15 1996, In : Science. 274, 5284, p. 99-102 4 p.

Research output: Contribution to journalArticle

3418 Scopus citations

Cytoskeletal pathology in non-Alzheimer degenerative dementia: New lesions in diffuse Lewy body disease, Pick's disease, and corticobasal degeneration

Dickson, D. W., Feany, M. B., Yen, S. H., Mattiace, L. A. & Davies, P., 1996, In : Journal of Neural Transmission, Supplement. 47, p. 31-46 16 p.

Research output: Contribution to journalArticle

57 Scopus citations

Enhanced binding of advanced glycation endproducts (age) by apo e4 isotype linkt mechanisms of plaque deposition in alzheimer's disease

Li, Y. M., Dickson, D. & Vlassara, H., Dec 1 1996, In : FASEB Journal. 10, 3, p. A677

Research output: Contribution to journalArticle

3 Scopus citations

Erratum: Accumulation of β-amyloid fibrils in pancreas of transgenic mice (Neurobiology of Aging (1996) 17 (215-222))

Kawarabayashi, T., Shoji, M., Sato, M., Sasaki, A., Ho, L., Eckman, C. B., Prada, M., Younkin, S. G., Kobayashi, T., Tada, N., Matsubara, E., Iizuka, T., Harigaya, Y., Kasai, K. & Hirai, S., Jan 1 1996, In : Neurobiology of aging. 17, 4, 1 p.

Research output: Contribution to journalComment/debate

Familial Alzheimer's disease-linked presenilin I variants elevate aβ1- 42/1-40 ratio in vitro and in vivo

Borchelt, D. R., Thinakaran, G., Eckman, C. B., Lee, M. K., Davenport, F., Ratovitsky, T., Prada, C. M., Kim, G., Seekins, S., Yager, D., Slunt, H. H., Wang, R., Seeger, M., Levey, A. I., Gandy, S. E., Copeland, N. G., Jenkins, N. A., Price, D. L., Younkin, S. G. & Sisodia, S. S., Nov 1996, In : Neuron. 17, 5, p. 1005-1013 9 p.

Research output: Contribution to journalArticle

1267 Scopus citations

Glycation and microglial reaction in lesions of Alzheimer's disease

Dickson, D. W., Sinicropi, S., Yen, S. H., Ko, L. W., Mattiace, L. A., Bucala, R. & Vlassara, H., Jan 1 1996, In : Neurobiology of aging. 17, 5, p. 733-743 11 p.

Research output: Contribution to journalArticle

75 Scopus citations

Glycoinositol phospholipid anchor and protein C-terminus of bovine erythrocyte acetylcholinesterase: Analysis by mass spectrometry and by protein and DNA sequencing

Haas, R., Jackson, B. C., Reinhold, B., Foster, J. D. & Rosenberry, T. L., Mar 15 1996, In : Biochemical Journal. 314, 3, p. 817-825 9 p.

Research output: Contribution to journalArticle

23 Scopus citations

High levels of circulating β-amyloid peptide do not cause cerebral β- amyloidosis in transgenic mice

Fukuchi, K. I., Ho, L., Younkin, S. G., Kunkel, D. D., Ogburn, C. E., LeBoeuf, R. C., Furlong, C. E., Deeb, S. S., Nochlin, D., Wegiel, J., Wisniewski, H. M. & Martin, G. M., Jul 1 1996, In : American Journal of Pathology. 149, 1, p. 219-227 9 p.

Research output: Contribution to journalArticle

65 Scopus citations

Immunohistochemical localization of capsular polysaccharide antigen in the central nervous system cells in cryptococcal meningoencephalitis

Lee, S. C., Casadevall, A. & Dickson, D. W., Apr 1996, In : American Journal of Pathology. 148, 4, p. 1267-1274 8 p.

Research output: Contribution to journalArticle

63 Scopus citations

Increased amyloid-β42(43) in brains of mice expressing mutant presenilin 1

Duff, K., Eckman, C., Zehr, C., Yu, X., Prada, C. M., Perez-Tur, J., Hutton, M., Buee, L., Harigaya, Y., Yager, D., Morgan, D., Gordon, M. N., Holcomb, L., Refolo, L., Zenk, B., Hardy, J. & Younkin, S., Jan 1 1996, In : Nature. 383, 6602, p. 710-713 4 p.

Research output: Contribution to journalArticle

1273 Scopus citations

In vitro polymerization of embryonic MAP-2c and fragments of the MAP-2 microtubule binding region into structures resembling paired helical filaments

DeTure, M. A., Zhang, E. Y., Bubb, M. R. & Purich, D. L., Dec 1 1996, In : Journal of Biological Chemistry. 271, 51, p. 32702-32706 5 p.

Research output: Contribution to journalArticle

14 Scopus citations

Involvement of D-aspartic acid in the synthesis of testosterone in rat testes

D'Aniello, A., Di Cosmo, A., Di Cristo, C., Annunziato, L., Petrucelli, L. & Fisher, G., Jul 7 1996, In : Life Sciences. 59, 2, p. 97-104 8 p.

Research output: Contribution to journalArticle

147 Scopus citations

Microglial nodule encephalitis: Limited CNS infection despite disseminated systemic cryptococcosis

Edelman, M., Birkenhauer, M. C., Steinberg, J. J., Dickson, D. W., Casadevall, A. & Lee, S. C., 1996, In : Clinical Neuropathology. 15, 1, p. 30-33 4 p.

Research output: Contribution to journalArticle

11 Scopus citations

Modulated induction of tau proteins in cultured human neuroblastoma cells

Ko, L. W., Liu, W. K., Georgieff, I. S. & Yen, S. H. C., Jan 29 1996, In : Brain Research. 707, 2, p. 256-265 10 p.

Research output: Contribution to journalArticle

5 Scopus citations

Neurodegenerative disorders with extensive tau pathology: A comparative study and review

Feany, M. B. & Dickson, D. W., Aug 1996, In : Annals of neurology. 40, 2, p. 139-148 10 p.

Research output: Contribution to journalReview article

244 Scopus citations

Neuropathologic overlap of progressive supranuclear palsy, Pick's disease and corticobasal degeneration

Feany, M. B., Mattiace, L. A. & Dickson, D. W., Jan 1996, In : Journal of Neuropathology and Experimental Neurology. 55, 1, p. 53-67 15 p.

Research output: Contribution to journalArticle

Open Access
242 Scopus citations

New thiazolo[3,2-a] pyrimidine derivatives, synthesis and calcium antagonistic activities

Balkan, A., Tozkoparan, B., Ertan, M., Sara, Y. & Ertekin, N., Dec 1 1996, In : Bollettino Chimico Farmaceutico. 135, 11, p. 648-652 5 p.

Research output: Contribution to journalArticle

5 Scopus citations