Jacksonville, FL

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Alzheimer Disease Medicine & Life Sciences
Neoplasms Medicine & Life Sciences
Breast Neoplasms Medicine & Life Sciences
Therapeutics Medicine & Life Sciences
Parkinson Disease Medicine & Life Sciences
Mutation Medicine & Life Sciences
Stroke Medicine & Life Sciences
Frontotemporal Dementia Medicine & Life Sciences

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Projects 1975 2021

Tauopathies
Genes
Progressive Supranuclear Palsy
Research
Parkinsonian Disorders

Zinc-targeting inhibitors of insulin-degrading enzyme

Leissring, M. A.

National Institutes of Health

9/1/167/31/21

Project: Research project

Insulysin
Zinc
Enzyme Inhibitors
Metals
Insulin
Neoplastic Stem Cells
Lung Neoplasms
Phenotype
Therapeutics
Neoplasms

Research Output 1976 2019

5-HT3 antagonist ondansetron increases apoE secretion by modulating the LXR-ABCA1 pathway

Shinohara, M., Shinohara, M., Zhao, J., Fu, Y., Liu, C-C., Kanekiyo, T. & Bu, G. D., Mar 2 2019, In : International Journal of Molecular Sciences. 20, 6, 1488.

Research output: Contribution to journalArticle

Open Access
Serotonin 5-HT3 Receptor Antagonists
Ondansetron
secretions
Apolipoproteins E
liver

Abdominal Pain in Patients with Gastroparesis: Associations with Gastroparesis Symptoms, Etiology of Gastroparesis, Gastric Emptying, Somatization, and Quality of Life

Parkman, H. P., Wilson, L. A., Hasler, W. L., McCallum, R. W., Sarosiek, I., Koch, K. L., Abell, T. L., Schey, R., Kuo, B., Snape, W. J., Nguyen, L., Farrugia, G., Grover, M., Clarke, J., Miriel, L., Tonascia, J., Hamilton, F. & Pasricha, P. J., Jan 1 2019, In : Digestive Diseases and Sciences.

Research output: Contribution to journalArticle

Gastroparesis
Gastric Emptying
Abdominal Pain
Quality of Life
Opiate Alkaloids
3 Citations (Scopus)

Aberrant deposition of stress granule-resident proteins linked to C9orf72-associated TDP-43 proteinopathy

Chew, J., Cook, C., Gendron, T. D., Jansen-West, K., Del Rosso, G., Daughrity, L. M., Castanedes-Casey, M., Kurti, A., Stankowski, J. N., Disney, M. D., Rothstein, J. D., Dickson, D. W., Fryer, J. D., Zhang, Y. & Petrucelli, L., Feb 15 2019, In : Molecular neurodegeneration. 14, 1, 1 p.

Research output: Contribution to journalArticle

TDP-43 Proteinopathies
Dipeptides
RNA
Proteins
Antisense RNA