Jacksonville, FL

Research Output 1976 2020

2020

Molecular and phenotypic characterization of an early T-cell precursor acute lymphoblastic lymphoma harboring PICALM-MLLT10 fusion with aberrant expression of B-cell antigens

Khurana, S., Melody, M. E., Ketterling, R. P., Peterson, J. F., Luoma, I. M., Vazmatzis, G., Tun, H. W., Foran, J. M. & Jiang, L., Jan 2020, In : Cancer Genetics. 240, p. 40-44 5 p.

Research output: Contribution to journalArticle

Precursor T-Cell Lymphoblastic Leukemia-Lymphoma
DNA Nucleotidylexotransferase
B-Lymphocytes
Antigens
Diagnostic Errors
2019
4 Citations (Scopus)

3D porous chitosan-alginate scaffold stiffness promotes differential responses in prostate cancer cell lines

Xu, K., Ganapathy, K., Andl, T., Wang, Z., Copland, J. A. III., Chakrabarti, R. & Florczyk, S. J., Oct 1 2019, In : Biomaterials. 217, 119311.

Research output: Contribution to journalArticle

Alginate
Chitosan
Scaffolds
Prostatic Neoplasms
Cells
10 Citations (Scopus)

3D-printed flexible polymer stents for potential applications in inoperable esophageal malignancies

Lin, M., Firoozi, N., Tsai, C. T., Wallace, M. B. & Kang, Y., Jan 1 2019, In : Acta Biomaterialia. 83, p. 119-129 11 p.

Research output: Contribution to journalArticle

Stents
Polymers
Neoplasms
Esophagus
Cytotoxicity
1 Citation (Scopus)

4-Repeat tau seeds and templating subtypes as brain and CSF biomarkers of frontotemporal lobar degeneration

Saijo, E., Metrick, M. A., Koga, S., Parchi, P., Litvan, I., Spina, S., Boxer, A., Rojas, J. C., Galasko, D., Kraus, A., Rossi, M., Newell, K., Zanusso, G., Grinberg, L. T., Seeley, W. W., Ghetti, B., Dickson, D. W. & Caughey, B., Jan 1 2019, (Accepted/In press) In : Acta neuropathologica.

Research output: Contribution to journalArticle

Frontotemporal Lobar Degeneration
Tauopathies
Progressive Supranuclear Palsy
Cerebrospinal Fluid
Seeds

5-HT3 antagonist ondansetron increases apoE secretion by modulating the LXR-ABCA1 pathway

Shinohara, M., Shinohara, M., Zhao, J., Fu, Y., Liu, C-C., Kanekiyo, T. & Bu, G. D., Mar 2 2019, In : International Journal of Molecular Sciences. 20, 6, 1488.

Research output: Contribution to journalArticle

Open Access
Serotonin 5-HT3 Receptor Antagonists
Ondansetron
secretions
Apolipoproteins E
liver
1 Citation (Scopus)

Abdominal Pain in Patients with Gastroparesis: Associations with Gastroparesis Symptoms, Etiology of Gastroparesis, Gastric Emptying, Somatization, and Quality of Life

Parkman, H. P., Wilson, L. A., Hasler, W. L., McCallum, R. W., Sarosiek, I., Koch, K. L., Abell, T. L., Schey, R., Kuo, B., Snape, W. J., Nguyen, L., Farrugia, G., Grover, M., Clarke, J., Miriel, L., Tonascia, J., Hamilton, F. & Pasricha, P. J., Jan 1 2019, In : Digestive Diseases and Sciences.

Research output: Contribution to journalArticle

Gastroparesis
Gastric Emptying
Abdominal Pain
Quality of Life
Opiate Alkaloids
8 Citations (Scopus)

Aberrant deposition of stress granule-resident proteins linked to C9orf72-associated TDP-43 proteinopathy

Chew, J., Cook, C., Gendron, T. D., Jansen-West, K., Del Rosso, G., Daughrity, L. M., Castanedes-Casey, M., Kurti, A., Stankowski, J. N., Disney, M. D., Rothstein, J. D., Dickson, D. W., Fryer, J. D., Zhang, Y. & Petrucelli, L., Feb 15 2019, In : Molecular neurodegeneration. 14, 1, 1 p.

Research output: Contribution to journalArticle

TDP-43 Proteinopathies
Dipeptides
RNA
Proteins
Antisense RNA
1 Citation (Scopus)

Aberrant lipid metabolism as a therapeutic target in liver cancer

Pope, E. D., Kimbrough, E. O., Vemireddy, L. P., Surapaneni, P. K., Copland, J. A. III. & Mody, K., Jun 3 2019, In : Expert opinion on therapeutic targets. 23, 6, p. 473-483 11 p.

Research output: Contribution to journalArticle

Liver Neoplasms
Lipid Metabolism
Liver
Hepatocellular Carcinoma
Fatty Acids
3 Citations (Scopus)

A blood-based signature of cerebrospinal fluid Aβ 1–42 status

Alzheimer’s Disease Metabolomics Consortium & Alzheimer’s Disease Neuroimaging Initiative, Dec 1 2019, In : Scientific reports. 9, 1, 4163.

Research output: Contribution to journalArticle

Open Access
Cerebrospinal Fluid
Amyloid
Alzheimer Disease
Positron-Emission Tomography
Area Under Curve

A brain somatic RHEB doublet mutation causes focal cortical dysplasia type II

Zhao, S., Li, Z., Zhang, M., Zhang, L., Zheng, H., Ning, J., Wang, Y., Wang, F., Zhang, X., Gan, H., Wang, Y., Zhang, X., Luo, H., Bu, G. D., Xu, H., Yao, Y. & Zhang, Y. W., Jul 1 2019, In : Experimental and Molecular Medicine. 51, 7, 84.

Research output: Contribution to journalArticle

Open Access
Phosphorylation
Brain
Mutation
Electroencephalography
Neurons

A care process model to deliver177Lu-DOTATATE peptide receptor radionuclide therapy for patients with neuroendocrine tumors

Kasi, P. M., Maige, C. L., Shahjehan, F., Rodgers, J. M., Aloszka, D. L., Ritter, A., Andrus, M. L., Mcmillan, J. M., Mody, K., Sharma, A. & Jain, M. K., Jan 1 2019, In : Frontiers in Oncology. 9, JAN, 663.

Research output: Contribution to journalArticle

Open Access
Peptide Receptors
Neuroendocrine Tumors
Radioisotopes
Therapeutics
Clinical Trials

A community health case for psychiatric care: A cross-sectional study of county health rankings

Spaulding, A., Stallings-Smith, S., Hamadi, H., Park, S., Niazi, S. & Apatu, E., Mar 1 2019, In : General Hospital Psychiatry. 57, p. 1-6 6 p.

Research output: Contribution to journalArticle

Psychiatry
Cross-Sectional Studies
Mental Health Services
Health
Logistic Models
1 Citation (Scopus)

A comprehensive screening of copy number variability in dementia with Lewy bodies

Kun-Rodrigues, C., Orme, T., Carmona, S., Hernandez, D. G., Ross, O. A., Eicher, J. D., Shepherd, C., Parkkinen, L., Darwent, L., Heckman, M. G., Scholz, S. W., Troncoso, J. C., Pletnikova, O., Dawson, T., Rosenthal, L., Ansorge, O., Clarimon, J., Lleo, A., Morenas-Rodriguez, E., Clark, L. & 48 others, Honig, L. S., Marder, K., Lemstra, A., Rogaeva, E., St. George-Hyslop, P., Londos, E., Zetterberg, H., Barber, I., Braae, A., Brown, K., Morgan, K., Troakes, C., Al-Sarraj, S., Lashley, T., Holton, J., Compta, Y., Van Deerlin, V., Serrano, G. E., Beach, T. G., Lesage, S., Galasko, D., Masliah, E., Santana, I., Pastor, P., Diez-Fairen, M., Aguilar, M., Tienari, P. J., Myllykangas, L., Oinas, M., Revesz, T., Lees, A., Boeve, B. F., Petersen, R. C., Ferman, T. J., Escott-Price, V., Graff Radford, N. R., Cairns, N. J., Morris, J. C., Pickering-Brown, S., Mann, D., Halliday, G. M., Hardy, J., Trojanowski, J. Q., Dickson, D. W., Singleton, A., Stone, D. J., Guerreiro, R. & Bras, J., Mar 1 2019, In : Neurobiology of Aging. 75, p. 223.e1-223.e10

Research output: Contribution to journalArticle

Lewy Body Disease
Genome
Neurodegenerative Diseases
Genes
Dementia

A Cross-Sectional Analysis of Migraine-Related Disability in CADASIL: A Mayo Clinic Cohort

Goldstein, E. D., Badi, M. K., Klaas, J. P., Glover, P., Rozen, T. D., Huang, J. F., Lin, M. P. & Meschia, J. F., Nov 1 2019, In : Neurologist. 24, 6, p. 161-164 4 p.

Research output: Contribution to journalArticle

CADASIL
Migraine Disorders
Cross-Sectional Studies
Epilepsy
Migraine with Aura
8 Citations (Scopus)

Acute myeloid leukemia, version 3.2019

Tallman, M. S., Wang, E. S., Altman, J. K., Appelbaum, F. R., Bhatt, V. R., Bixby, D., Coutre, S. E., De Lima, M., Fathi, A. T., Fiorella, M., Foran, J. M., Hall, A. C., Jacoby, M., Lancet, J., LeBlanc, T. W., Mannis, G., Marcucci, G., Martin, M. G., Mims, A., O'Donnell, M. R. & 14 others, Olin, R., Peker, D., Perl, A., Pollyea, D. A., Pratz, K., Prebet, T., Ravandi, F., Shami, P. J., Stone, R. M., Strickland, S. A., Wieduwilt, M., Gregory, K. M., Hammond, L. & Ogba, N., Jan 1 2019, In : JNCCN Journal of the National Comprehensive Cancer Network. 17, 6, p. 721-749 29 p.

Research output: Contribution to journalArticle

Open Access
Acute Myeloid Leukemia
Leukemia
Practice Guidelines
Therapeutics
Guidelines

Acute pancreatitis in end-stage renal disease patients in the USA: A nationwide, propensity score-matched analysis

Cheungpasitporn, W., Thongprayoon, C., Ungprasert, P., Wijarnpreecha, K., Raimondo, M. & Kroner, P. T., Aug 1 2019, In : European Journal of Gastroenterology and Hepatology. 31, 8, p. 968-972 5 p.

Research output: Contribution to journalArticle

Propensity Score
Pancreatitis
Chronic Kidney Failure
Kidney
Inpatients
6 Citations (Scopus)

ADAR2 mislocalization and widespread RNA editing aberrations in C9orf72-mediated ALS/FTD

Moore, S., Alsop, E., Lorenzini, I., Starr, A., Rabichow, B. E., Mendez, E., Levy, J. L., Burciu, C., Reiman, R., Chew, J., Belzil, V., W. Dickson, D., Robertson, J., Staats, K. A., Ichida, J. K., Petrucelli, L., Van Keuren-Jensen, K. & Sattler, R., Jan 1 2019, In : Acta neuropathologica.

Research output: Contribution to journalArticle

RNA Editing
Adenosine Deaminase
RNA
Amyotrophic Lateral Sclerosis
Eukaryotic Initiation Factor-2

Addressing gender in gastroenterology: opportunities for change

Rabinowitz, L. G., Anandasabapathy, S., Sethi, A., Siddiqui, U. D., Wallace, M. B. & Kim, M. K., Jan 1 2019, (Accepted/In press) In : Gastrointestinal endoscopy.

Research output: Contribution to journalArticle

Gastroenterology
1 Citation (Scopus)

Adipose-derived cellular and cell-derived regenerative therapies in dermatology and aesthetic rejuvenation

Suh, A., Pham, A., Cress, M. J., Pincelli, T., TerKonda, S. P., Bruce, A., Zubair, A., Wolfram, J. & Shapiro, S. A., Sep 1 2019, In : Ageing Research Reviews. 54, 100933.

Research output: Contribution to journalReview article

Dermatology
Rejuvenation
Esthetics
Tissue
Cellular Structures
12 Citations (Scopus)

Adjuvant Anti-HER2 Therapy, Treatment-Related Amenorrhea, and Survival in Premenopausal HER2-Positive Early Breast Cancer Patients

Lambertini, M., Campbell, C., Bines, J., Korde, L. A., Izquierdo, M., Fumagalli, D., Del Mastro, L., Ignatiadis, M., Pritchard, K., Wolff, A. C., Jackisch, C., Lang, I., Untch, M., Smith, I., Boyle, F., Xu, B., Barrios, C. H., Baselga, J., Moreno Aspitia, A., Piccart, M. & 2 others, Gelber, R. D. & de Azambuja, E., Jan 1 2019, In : Journal of the National Cancer Institute. 111, 1, p. 86-94 9 p.

Research output: Contribution to journalArticle

Amenorrhea
Breast Neoplasms
Survival
Hormones
Therapeutics

Adult EEG

Feyissa, A. & Tatum, W. O., Jan 1 2019, Handbook of Clinical Neurology. Elsevier B.V., p. 103-124 22 p. (Handbook of Clinical Neurology; vol. 160).

Research output: Chapter in Book/Report/Conference proceedingChapter

Electroencephalography
Epilepsy
Seizures
Brain
Brain Diseases
1 Citation (Scopus)

AFM study: Cell cycle and probe geometry influences nanomechanical characterization of Panc1 cells

Kulkarni, T., Tam, A., Mukhopadhyay, D. & Bhattacharya, S., May 1 2019, In : Biochimica et Biophysica Acta - General Subjects. 1863, 5, p. 802-812 11 p.

Research output: Contribution to journalArticle

Cell Cycle
Microscopes
Cells
Geometry
Cell Cycle Resting Phase
3 Citations (Scopus)

A Human iPSC-derived 3D platform using primary brain cancer cells to study drug development and personalized medicine

Plummer, S., Wallace, S., Ball, G., Lloyd, R., Schiapparelli, P., Quinones-Hinojosa, A., Hartung, T. & Pamies, D., Dec 1 2019, In : Scientific reports. 9, 1, 1407.

Research output: Contribution to journalArticle

Open Access
temozolomide
Precision Medicine
Glioblastoma
Brain Neoplasms
Doxorubicin

AI-assisted in situ detection of human glioma infiltration using a novel computational method for optical coherence tomography

Juarez-Chambi, R. M., Kut, C., Rico-Jimenez, J. J., Chaichana, K. L., Xi, J., Campos-Delgado, D. U., Rodriguez, F. J., Quinones-Hinojosa, A., Li, X. & Jo, J. A., Nov 1 2019, In : Clinical Cancer Research. 25, 21, p. 6329-6338 10 p.

Research output: Contribution to journalArticle

Artificial Intelligence
Optical Coherence Tomography
Glioma
Brain
Calibration
1 Citation (Scopus)

Akt Phosphorylates NQO1 and Triggers its Degradation, Abolishing Its Antioxidative Activities in Parkinson's Disease

Luo, S., Kang, S. S., Wang, Z. H., Liu, X., Day, J. X., Wu, Z., Peng, J., Xiang, D., Springer, W. & Ye, K., Sep 11 2019, In : The Journal of neuroscience : the official journal of the Society for Neuroscience. 39, 37, p. 7291-7305 15 p.

Research output: Contribution to journalArticle

Parkinson Disease
Oxidoreductases
Ubiquitin-Protein Ligases
Dopamine
Oxidative Stress
1 Citation (Scopus)

Allogeneic hematopoietic cell transplantation compared to chemotherapy consolidation in older acute myeloid leukemia (AML) patients 60–75 years in first complete remission (CR1): an alliance (A151509), SWOG, ECOG-ACRIN, and CIBMTR study

Ustun, C., Le-Rademacher, J., Wang, H. L., Othus, M., Sun, Z., Major, B., Zhang, M. J., Storrick, E., Lafky, J. M., Chow, S., Mrózek, K., Attar, E. C., Nand, S., Bloomfield, C. D., Cripe, L. D., Tallman, M. S., Appelbaum, F., Larson, R. A., Marcucci, G., Roboz, G. J. & 12 others, Uy, G. L., Stone, R. M., Jatoi, A., Shea, T. C., de Lima, M., Foran, J. M., Sandmaier, B. M., Litzow, M. R., Erba, H. P., Hurria, A., Weisdorf, D. J. & Artz, A. S., Jan 1 2019, In : Leukemia.

Research output: Contribution to journalArticle

Open Access
Consolidation Chemotherapy
Cell Transplantation
Acute Myeloid Leukemia
Drug Therapy
Survival

Ambulatory Blood Pressure Monitoring: Profiles in Chronic Kidney Disease Patients and Utility in Management

Aslam, N., Missick, S. & Haley, W. E., Mar 1 2019, In : Advances in Chronic Kidney Disease. 26, 2, p. 92-98 7 p.

Research output: Contribution to journalReview article

Ambulatory Monitoring
Ambulatory Blood Pressure Monitoring
Chronic Renal Insufficiency
Blood Pressure
Masked Hypertension

A microphysiological model of the bronchial airways reveals the interplay of mechanical and biochemical signals in bronchospasm

Kilic, O., Yoon, A., Shah, S. R., Yong, H. M., Ruiz-Valls, A., Chang, H., Panettieri, R. A., Liggett, S. B., Quinones-Hinojosa, A., An, S. S. & Levchenko, A., Jan 1 2019, In : Nature Biomedical Engineering.

Research output: Contribution to journalArticle

Bronchial Spasm
Asthma
Smooth Muscle
Epithelial Cells
Molecular Models

Amplification of 9p24.1 in diffuse large B-cell lymphoma identifies a unique subset of cases that resemble primary mediastinal large B-cell lymphoma

Wang, Y., Wenzl, K., Manske, M. K., Asmann, Y., Sarangi, V., Greipp, P. T., Krull, J. E., Hartert, K., He, R., Feldman, A. L., Maurer, M. J., Slager, S. L., Nowakowski, G. S., Habermann, T. M., Witzig, T. E., Link, B. K., Ansell, S. M., Cerhan, J. R. & Novak, A. J., Sep 1 2019, In : Blood cancer journal. 9, 9, 73.

Research output: Contribution to journalArticle

Open Access
Lymphoma, Large B-Cell, Diffuse
B-Cell Lymphoma
Immunotherapy
Lymphoma
Hodgkin Disease

Analysis of Melanoma in African American Patients in the United States

Boczar, D., Restrepo, D. J., Sisti, A., Huayllani, M. T., Saleem, H. Y., Lu, X., Cinotto, G., Manrique, O. J., Spaulding, A. C. & Forte, A. J., Nov 1 2019, In : Anticancer research. 39, 11, p. 6333-6337 5 p.

Research output: Contribution to journalArticle

African Americans
Melanoma
Neoplasm Staging
Autopsy
Neoplasms

Anastrozole Aromatase Inhibitor Plasma Drug Concentration Genome-Wide Association Study: Functional Epistatic Interaction Between SLC38A7 and ALPPL2

Dudenkov, T. M., Liu, D., Cairns, J., Devarajan, S., Zhuang, Y., Ingle, J. N., Buzdar, A. U., Robson, M. E., Kubo, M., Batzler, A., Barman, P., Jenkins, G. D., Carlson, E. E., Goetz, M. P., Northfelt, D. W., Moreno Aspitia, A., Desta, Z., Reid, J. M., Kalari, K. R., Wang, L. M. & 1 others, Weinshilboum, R. M., Jan 1 2019, In : Clinical pharmacology and therapeutics.

Research output: Contribution to journalArticle

Open Access
Aromatase Inhibitors
Genome-Wide Association Study
Single Nucleotide Polymorphism
Pharmaceutical Preparations
Breast Neoplasms

An atlas of cortical circular RNA expression in Alzheimer disease brains demonstrates clinical and pathological associations

the Dominantly Inherited Alzheimer Network (DIAN), Nov 1 2019, In : Nature Neuroscience. 22, 11, p. 1903-1912 10 p.

Research output: Contribution to journalArticle

Atlases
Alzheimer Disease
RNA
MicroRNAs
Brain
3 Citations (Scopus)

A nonsynonymous mutation in PLCG2 reduces the risk of Alzheimer’s disease, dementia with Lewy bodies and frontotemporal dementia, and increases the likelihood of longevity

DESGESCO (Dementia Genetics Spanish Consortium), EADB (Alzheimer Disease European DNA biobank), EADB (Alzheimer Disease European DNA biobank), IFGC (International FTD-Genomics Consortium), IPDGC (The International Parkinson Disease Genomics Consortium), IPDGC (The International Parkinson Disease Genomics Consortium), RiMod-FTD (Risk and Modifying factors in Fronto-Temporal Dementia), Netherlands Brain Bank (NBB) & The GIFT (Genetic Investigation in Frontotemporal Dementia and Alzheimer’s Disease) Study Group, Aug 1 2019, In : Acta neuropathologica. 138, 2, p. 237-250 14 p.

Research output: Contribution to journalArticle

Open Access
Lewy Body Disease
Frontotemporal Dementia
Alzheimer Disease
Mutation
Neurodegenerative Diseases

A novel multi-target small molecule, LCC-09, inhibits stemness and therapy-resistant phenotypes of glioblastoma cells by increasing MIR-34a and deregulating the DRD4/AKT/MTOR signaling axis

Wen, Y. T., Wu, A. T., Bamodu, O. A., Wei, L., Lin, C. M., Yen, Y., Chao, T. Y., Mukhopadhyay, D., Hsiao, M. & Huang, H. S., Oct 2019, In : Cancers. 11, 10, 1442.

Research output: Contribution to journalArticle

Open Access
temozolomide
Glioblastoma
Phenotype
Glioma
Stem Cells

A novel muscle cramp scale (MCS) in amyotrophic lateral sclerosis (ALS)

Mitsumoto, H., Chiuzan, C., Gilmore, M., Zhang, Y., Ibagon, C., McHale, B., Hupf, J. & Oskarsson, B., Jan 1 2019, In : Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration.

Research output: Contribution to journalArticle

Muscle Cramp
Amyotrophic Lateral Sclerosis
Telephone

A novel variant in FN1 in a family with fibronectin glomerulopathy

Aslam, N., Singh, A., Cortese, C. & Riegert-Johnson, D. L., Dec 1 2019, In : Human Genome Variation. 6, 1, 11.

Research output: Contribution to journalArticle

Open Access
Fibronectins
Exome
Deposits
Genes
Mutation
2 Citations (Scopus)

An RCVS Spectrum Disorder? New Daily Persistent Headache Starting as a Single Thunderclap Headache (3 New Cases)

Jamali, S. A. & Rozen, T., Jan 1 2019, In : Headache.

Research output: Contribution to journalArticle

Primary Headache Disorders
Headache
Nimodipine
Intracranial Vasospasm
Headache Disorders

Antemortem volume loss mirrors TDP-43 staging in older adults with non-frontotemporal lobar degeneration

Bejanin, A., Murray, M. E., Martin, P., Botha, H., Tosakulwong, N., Schwarz, C. G., Senjem, M. L., Chételat, G., Kantarci, K., Jack, C. R., Boeve, B. F., Knopman, D. S., Petersen, R. C., Giannini, C., Parisi, J. E., Dickson, D. W., Whitwell, J. L. & Josephs, K. A., Nov 1 2019, In : Brain : a journal of neurology. 142, 11, p. 3621-3635 15 p.

Research output: Contribution to journalArticle

Temporal Lobe
Pathology
Alzheimer Disease
Frontotemporal Lobar Degeneration
Lewy Bodies
9 Citations (Scopus)

Antibodies Against Chlamydia trachomatis and Ovarian Cancer Risk in Two Independent Populations

Trabert, B., Waterboer, T., Idahl, A., Brenner, N., Brinton, L. A., Butt, J., Coburn, S. B., Hartge, P., Hufnagel, K., Inturrisi, F., Lissowska, J., Mentzer, A., Peplonska, B., Sherman, M. E., Wills, G. S., Woodhall, S. C., Pawlita, M. & Wentzensen, N., Feb 1 2019, In : Journal of the National Cancer Institute. 111, 2, p. 129-136 8 p.

Research output: Contribution to journalArticle

Open Access
Chlamydia trachomatis
Ovarian Neoplasms
Antibodies
Odds Ratio
Population

A phase 1 and randomized, placebo-controlled phase 2 trial of bevacizumab plus dasatinib in patients with recurrent glioblastoma: Alliance/North Central Cancer Treatment Group N0872

Galanis, E., Anderson, S. K., Twohy, E. L., Carrero, X. W., Dixon, J. G., Tran, D. D., Jeyapalan, S. A., Anderson, D. M., Kaufmann, T. J., Feathers, R. W., Giannini, C., Buckner, J. C., Anastasiadis, P. Z. & Schiff, D., Jan 1 2019, In : Cancer.

Research output: Contribution to journalArticle

Glioblastoma
Placebos
Neoplasms
Therapeutics
National Cancer Institute (U.S.)
1 Citation (Scopus)

A phase 1 and randomized controlled phase 2 trial of the safety and efficacy of the combination of gemcitabine and docetaxel with ontuxizumab (MORAb-004) in metastatic soft-tissue sarcomas

Jones, R. L., Chawla, S. P., Attia, S., Schöffski, P., Gelderblom, H., Chmielowski, B., Le Cesne, A., Van Tine, B. A., Trent, J. C., Patel, S., Wagner, A. J., Chugh, R., Heyburn, J. W., Weil, S. C., Wang, W., Viele, K. & Maki, R. G., Jan 1 2019, In : Cancer.

Research output: Contribution to journalArticle

Open Access
docetaxel
gemcitabine
Sarcoma
Confidence Intervals
Safety

ApoE-2 Brain-Targeted Gene Therapy Through Transferrin and Penetratin Tagged Liposomal Nanoparticles

Dos Santos Rodrigues, B., Kanekiyo, T. & Singh, J., Sep 16 2019, In : Pharmaceutical research. 36, 11, 1 p.

Research output: Contribution to journalArticle

Gene therapy
Apolipoproteins E
Transferrin
Liposomes
Genetic Therapy
3 Citations (Scopus)

APOE4-mediated amyloid-β pathology depends on its neuronal receptor LRP1

Tachibana, M., Holm, M. L., Liu, C-C., Shinohara, M., Aikawa, T., Oue, H., Yamazaki, Y., Martens, Y. A., Murray, M. E., Sullivan, P. M., Weyer, K., Glerup, S., Dickson, D. W., Bu, G. D. & Kanekiyo, T., Mar 1 2019, In : Journal of Clinical Investigation. 129, 3, p. 1272-1277 6 p.

Research output: Contribution to journalArticle

LDL Receptors
Amyloid
Apolipoprotein E4
Pathology
Alzheimer Disease
1 Citation (Scopus)

Apolipoprotein E and Alzheimer disease: pathobiology and targeting strategies

Yamazaki, Y., Zhao, N., Caulfield, T., Liu, C-C. & Bu, G. D., Sep 1 2019, In : Nature Reviews Neurology. 15, 9, p. 501-518 18 p.

Research output: Contribution to journalReview article

Apolipoproteins E
Alzheimer Disease
Apolipoprotein E4
Alleles
Pathology

A pooled analysis of the cardiac events in the trastuzumab adjuvant trials

de Azambuja, E., Ponde, N., Procter, M., Rastogi, P., Cecchini, R. S., Lambertini, M., Ballman, K., Aspitia, A. M., Zardavas, D., Roca, L., Gelber, R. D., Piccart-Gebhart, M. & Suter, T., Jan 1 2019, (Accepted/In press) In : Breast Cancer Research and Treatment.

Research output: Contribution to journalArticle

Stroke Volume
Trastuzumab
Anthracyclines
Therapeutics
Heart Failure
1 Citation (Scopus)

A proteomic signature for dementia with Lewy bodies

O'Bryant, S. E., Ferman, T. J., Zhang, F., Hall, J., Pedraza, O. D., Wszolek, Z. K., Como, T., Julovich, D., Mattevada, S., Johnson, L. A., Edwards, M. & Graff Radford, N. R., Dec 1 2019, In : Alzheimer's and Dementia: Diagnosis, Assessment and Disease Monitoring. 11, p. 270-276 7 p.

Research output: Contribution to journalArticle

Open Access
Lewy Body Disease
Proteomics
Parkinson Disease
Dementia
Sensitivity and Specificity

Aqueductal Cerebrospinal Fluid Stroke Volume Flow in a Rodent Model of Chronic Communicating Hydrocephalus: Establishing a Homogeneous Study Population for Cerebrospinal Fluid Dynamics Exploration

Vivas-Buitrago, T., Lokossou, A., Jusué-Torres, I., Pinilla-Monsalve, G., Blitz, A. M., Herzka, D. A., Robison, J., Xu, J., Guerrero Cazares, H., Mori, S., Quinones-Hinojosa, A., Baledént, O. & Rigamonti, D., Jan 1 2019, In : World neurosurgery.

Research output: Contribution to journalArticle

Hydrodynamics
Hydrocephalus
Stroke Volume
Cerebrospinal Fluid
Rodentia
1 Citation (Scopus)

Are we assuming too much with our statistical assumptions? Lessons learned from the ALTTO trial

Holmes, E. M., Bradbury, I., Williams, L. S., Korde, L., De Azambuja, E., Fumagalli, D., Moreno-Aspitia, A., Baselga, J., Piccart-Gebhart, M., Dueck, A. C. & Gelber, R. D., Sep 1 2019, In : Annals of Oncology. 30, 9, p. 1507-1513 7 p.

Research output: Contribution to journalArticle

Randomized Controlled Trials
Medical Futility
Therapeutics
Patient Safety
Proportional Hazards Models

Arterial Blood Pressure at Liver Transplant Evaluation Predicts Renal Histology in Candidates With Renal Dysfunction

Wadei, H. M., Abader, P., Alsaad, A. A., Croome, K., Cortese, C., Geiger, X. J., Khouzam, S., Mai, M. L., Taner, C. B. & Keaveny, A. P., Dec 1 2019, In : Liver Transplantation. 25, 12, p. 1756-1767 12 p.

Research output: Contribution to journalArticle

Histology
Arterial Pressure
Blood Pressure
Transplants
Kidney
Open Access
Channelopathies
Migraine Disorders
Sleep
Chromosomes, Human, Pair 19
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