Jacksonville, FL

Projects 1975 2021

Active

Identifying genes and Pathways that impact Tau Toxicity in FTD

Dickson, D. W. & Petrucelli, L.

National Institutes of Health

9/30/166/30/21

Project: Research projectSpecialized Center--Cooperative Agreements

Tauopathies
Genes
Progressive Supranuclear Palsy
Research
Parkinsonian Disorders

Zinc-targeting inhibitors of insulin-degrading enzyme

Leissring, M. A.

National Institutes of Health

9/1/167/31/21

Project: Research projectResearch Project

Insulysin
Zinc
Enzyme Inhibitors
Metals
Insulin
Neoplastic Stem Cells
Lung Neoplasms
Phenotype
Therapeutics
Neoplasms

PKD1 signaling in the initiation of pancreatic cancer

Storz, P.

National Institutes of Health

12/1/1511/30/20

Project: Research projectResearch Project

Metaplasia
Pancreatic Neoplasms
Stem Cells
Neoplasms
Acinar Cells

Integrative translational discovery of vascular risk factors in aging and dementia

Bu, G. D., Mangravite, L. & Ertekin-Taner, N.

National Institutes of Health

9/30/158/31/20

Project: Research projectMulti-Year Funded Research Project Grant

Cerebral Amyloid Angiopathy
Dementia
Alzheimer Disease
Apolipoproteins E
Amyloid Plaques

The role of Clusterin in cerebral amyloid angiopathy

Fryer, J. D.

National Institutes of Health

9/30/158/31/20

Project: Research projectResearch Project

Cerebral Amyloid Angiopathy
Clusterin
Alzheimer Disease
Blood Vessels
Brain
Dipeptides
Proteins
Yeasts
Karyopherins
Neurons
Epithelial-Mesenchymal Transition
Extracellular Matrix
Breast
Epithelial Cells
NADPH Oxidase

Pathobiology of Neurodegeneration in C9ORF72 Repeat Expansion

Boylan, K. B., Petrucelli, L. & Dickson, D. W.

National Institutes of Health

9/30/146/30/19

Project: Research projectResearch Program Projects

Amyotrophic Lateral Sclerosis
Frontotemporal Lobar Degeneration
Methylation
RNA-Binding Proteins
Histones

The role of acetylation in regulating pathophysiology of tau

Petrucelli, L. & Wolozin, B.

National Institutes of Health

9/1/148/31/19

Project: Research projectResearch Project

Histone Deacetylases
Acetylation
Tauopathies
Antisense Oligonucleotides
Pathology
Quality Control
Unfolded Protein Response
Ubiquitin
Energy Metabolism
Parkinson Disease

Alliance for Clinical Trials in Oncology Operations Center

Perez, E. A., Bertagnolli, M. M., Bertagnolli, M. M., Fleming, G., George, S. & Bertagnolli, M. M.

National Institutes of Health, National Cancer Institute United States

4/17/142/28/19

Project: Research projectCooperative Clinical Research--Cooperative Agreements

Clinical Trials
Neoplasms
Research
National Academies of Science, Engineering, and Medicine (U.S.) Health and Medicine Division
Translational Medical Research

CREST-2 Clinical Coordinating Center

Meschia, J. F., Lal, B. & Brott, T.

National Institutes of Health

3/15/142/28/21

Project: Research projectResearch Project--Cooperative Agreements

Endarterectomy
Stroke
Carotid Stenosis
Carotid Endarterectomy
Hyperlipidemias
Apolipoprotein E4
Apolipoproteins E
Dendrites
Lipid Metabolism
Alzheimer Disease

Mayo Center for Cell Signaling in Gastroenterology

Boardman, L. A., Ekker, S. C., Mc Niven, M. A., Shah, V., La Russo, N. F., Mc Niven, M. A., Farrugia, G. & Mc Niven, M. A.

National Institutes of Health

9/1/098/31/19

Project: Research projectCenter Core Grants

Gastroenterology
Research
Technology
Research Personnel
Microscopy

Poisoning of PARP and Topoisomerase I to Treat Ovarian Cancer

Shridhar, V., Kaufmann, S. H., Cliby, W. A., Bible, K. C., Goode, E. L., Peng, K., Galanis, E., Knutson, K. L., Hartmann, L. C., Lingle, W. L., Oberg, A. L., Couch, F. J., Fields, A. P., Haluska, P. R. J., Long, H., Bell, D., Keeney, G., Lengyel, E. & Keeney, G.

National Institutes of Health

10/1/088/31/20

Project: Research projectSpecialized Center

Ovarian Neoplasms
alvocidib
Registries
Research
Translational Medical Research

Pathobiology of Diabetic Gastroenteropathy

Ordog, T., Robb, R. A., Bharucha, A. E., Szurszewski, J. H., Farrugia, G., Linden, D. R., Zhang, Z., Zhang, Z. H., Vernino, S., Jeong-Heon, L. & Lee, J. H.

National Institutes of Health

7/1/046/30/20

Project: Research projectResearch Program Projects

Gastric Emptying
Stomach
Interstitial Cells of Cajal
Gastroparesis
Glucagon-Like Peptide 1

C/EBPbeta Affects Mammary Epithelial Cell Phenotype

Radisky, D. C.

National Institutes of Health

11/16/01 → …

Project: Research projectPostdoctoral Individual National Research Service Award

Structural Investigations of Productive Enzyme Complexes

Radisky, E. S.

National Institutes of Health

8/1/01 → …

Project: Research projectPostdoctoral Individual National Research Service Award

Serine Proteases
Subtilisin
Enzymes
Catalysis
Substrates

MAYO ALZHEIMERS DISEASE RESEARCH CENTER

Petrucelli, L., Tangalos, E. G., Jack, C. R. J., Dickson, D. W., Boeve, B. F., Younkin, S. G., Kantarci, K. M., Smith, G. E., Rademakers, R. V., Petersen, R. C., Pankratz, V. S., Yen, S. C., Tangalos, E. G., Jack, C. R. J., Dickson, D. W., Vemuri, P. D., Lucas, J. A., Knopman, D. S., Hutton, M. L., Bu, G. D., Edland, S. D., Hutton, M. L., Clifford, J., Kokman, E., Ertekin-Taner, N., Hutton, M. L. & Ertekin-Taner, N.

National Institutes of Health

5/1/994/30/19

Project: Research projectSpecialized Center

Alzheimer Disease
Research
Dementia
Lewy Body Disease
Brain

BETA AMYLOID EFFECTS ON NEUROTROPHIC RECEPTORS

Petrucelli, L.

National Institutes of Health

3/1/99 → …

Project: Research projectPredoctoral Individual National Research Service Award

Cholinergic Neurons
Nerve Growth Factor
Amyloid
Alzheimer Disease
Cholinergic Agents
Kidney Neoplasms
Vascular Endothelial Growth Factor A
Renal Cell Carcinoma
Neoplasms
Carcinogenesis

NITRIC OXIDE, MUCINS AND CHOLELITHIASIS

Keaveny, A. P.

National Institutes of Health

4/10/98 → …

Project: Research projectPostdoctoral Individual National Research Service Award

NEUROBIOLOGY OF MILD COGNITIVE IMPAIRMENT IN THE ELDERLY

Dickson, D. W., Lah, J., Counts, S., Ikonomovic, M. D., Leurgans, S. E., Beckett, L., Trojanowski, J. Q., Levey, A., Binder, L. I., Dekosky, S., Mufson, E., Lah, J., Counts, S., Ikonomovic, M. D., Leurgans, S. E., Trojanowski, J. Q., Ikonomovic, M. D., Beckett, L. & Trojanowski, J. Q.

National Institutes of Health

9/1/971/31/19

Project: Research projectResearch Program Projects

Amyloid Plaques
Ubiquitin
Brain
Alzheimer Disease
Apolipoproteins E

STROMELYSIN-1 IN SQUAMOUS CELL CARCINOMA PROGRESSION

Crawford, H. H.

National Institutes of Health

9/27/95 → …

Project: Research projectPostdoctoral Individual National Research Service Award

POSTTRANSLATIONAL PROCESSING AND ACETYLCHOLINESTERASE

Rosenberry, T. L.

National Institutes of Health

3/12/87 → …

Project: Research project

ALZHEIMER'S DISEASE RESEARCH CENTER

Bu, G. D., Robins, L. E. E., Miller, T. M., Miller, J. P., Mintun, M. A., Harris, D., Snider, W., Edwards, D., Hale, S., Storandt, M., Schwartz, A., Miller, J. P., Mann Koepke, K., McKeel, D., Goate, A., Morris, J., Edwards, D., Hale, S., Schwartz, A., Merlie, J., Schmidt, D., Botwinick, J., Fagan, A., Denny, A., Willard, M., Toga, A., Musiek, E. S., Fulling, K., Cirrito, J., Robins, L. E. E., Schlesinger, M., Carr, D., O'Malley, K., Fischbach, G., Peck, W., Price, J., Olney, J., Berg, L., Snider, W., Miller, J. P., Mann Koepke, K., Buckner, R., Johnson, E., Holtzman, D., Cairns, N. J., Perrin, R. J., Galvin, J., Xiong, C., Miller, T. M., Goate, A., Morris, J., Kopan, R., Miller, J. P., Mintun, M. A., Meuser, T., Harris, D., McKeel, D., Miller, T. M. & Mintun, M. A.

National Institutes of Health

9/30/854/30/20

Project: Research projectSpecialized Center

TEACHING NURSING HOME

Dickson, D. W., Dickson, D. W., Lee, S., Hall, C., Verghese, J. O. E., Lipton, R., Sliwinski, M. J., Lee, S., Verghese, J. O. E., Sliwinski, M. J., Marantz, P., Grober, E., Cohen, D., Ritter, W., Hamerman, D., Golden, R., Katzman, R., Wolfson, L., Crystal, H., Buschke, H., Lipton, R., Crystal, H. & Buschke, H.

National Institutes of Health

9/29/825/31/21

Project: Research projectResearch Program Projects

Amyloid
Pathology
Dementia
Nursing Homes
Alzheimer Disease

CANCER CENTER SUPPORT GRANT (COMPREHENSIVE)

David, C. S., Jenkins, R. B., Cunningham, J. M., Wettstein, P. J., Buckner, J. C., Lingle, W. L., Kocher, J., Highsmith, W. E. J., Beebe, T. J., Vile, R. G., Okuno, S. H., Sarkaria, J. N., Alberts, S. R., Salisbury, J. L., Van Deursen, J., Diasio, R. B., Sargent, D. J., Thibodeau, S. N., Ingle, J. N., Reid, J. M., Colon-Otero, G., Galanis, E., Weinshilboum, R. M., Jenkins, R. B., Banks, P., Flotte, T., Kwon, E. D., Federspiel, M. J., Pitot, H. C., Dewald, G., Held, K., Liebson, P., Banks, P., Prendergast, F., Weiland, L., Wiebeu, E., Moertel, C., Clapham, D., Burnham, N., O'Connell, M., Spelsburg, T., Maihle, N., Katzmann, J., Wieand, H., Kovach, J., Wold, L., Grendahl, D., McCormick, D., Leibson, P., O'Fallon, J., Ames, M., Kline, B., Prendergast, F., Adjei, A., Chute, C., McKean, D., Highsmith, E., Raghavakaimal, S., Pitot, H., Greipp, P., Wieben, E., Roche, P., Leibson, P., Lawson, M., Grendahl, D., McCormick, D., Ames, M., Wieben, E. D., Flotte, T. J. & Adjei, A.

National Institutes of Health

3/1/802/28/19

Project: Research projectCenter Core Grants

Neoplasms
Research
Research Personnel
Cytogenetics
Biostatistics

MEDICAL SCIENTIST TRAINING PROGRAM

Younkin, S. G., Webster, L. T., Nilson, J. H., Webster, L. T., Nilson, J. H. & Harding, C.

National Institutes of Health

7/1/756/30/19

Project: Research projectInstitutional National Research Service Award

Suppressor CD8+ T cells in HIV infection

Elrefaei, M.

Project: Research project