• 113826 Citations
  • 149 Scopus h-Index
1974 …2019
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Research Output 1974 2019

Functional Activity and Neuropsychiatric Symptoms in Normal Aging and Mild Cognitive Impairment: The Mayo Clinic Study of Aging

Krell-Roesch, J., Cerhan, L. P., Machulda, M. M., Roberts, R. O., Mielke, M. M., Knopman, D. S., Syrjanen, J. A., Christianson, T. J., Petersen, R. C. & Geda, Y. E., Jan 1 2018, (Accepted/In press) In : Alzheimer Disease and Associated Disorders.

Research output: Contribution to journalArticle

Case-Control Studies
Cognitive Dysfunction

Functional and genetic analysis of haplotypic sequence variation at the nicastrin genomic locus.

Hamilton, G., Killick, R., Genetic, N. V., Translational Genomics Research Institute Consortium, G. R. I. C., Lambert, J. C., Amouyel, P., European Alzheimer Disease Initiative, A. D. I., Carrasquillo, M. M., Pankratz, V. S., Graff-Radford, N. R., Dickson, D. W., Petersen, R. C., Younkin, S. G., Powell, J. F. & Wade-Martins, R., Aug 2012, In : Neurobiology of Aging. 33, 8

Research output: Contribution to journalArticle

Bacterial Artificial Chromosomes
Sequence Analysis
Haplotypes
Amyloid Precursor Protein Secretases
Alzheimer Disease
43 Citations (Scopus)
Single Nucleotide Polymorphism
Alzheimer Disease
DNA
Apolipoproteins E
Proteins
105 Citations (Scopus)

Functional impact of white matter hyperintensities in cognitively normal elderly subjects

Murray, M. E., Senjem, M. L., Petersen, R. C., Hollman, J. H., Preboske, G. M., Weigand, S. D., Knopman, D. S., Ferman, T. J., Dickson, D. W. & Jack, C. R. J., Nov 2010, In : Archives of Neurology. 67, 11, p. 1379-1385 7 p.

Research output: Contribution to journalArticle

Parietal Lobe
Executive Function
Gait
Parkinson Disease
Dementia
60 Citations (Scopus)
Parietal Lobe
Magnetic Resonance Imaging
Aptitude
Gyrus Cinguli
Executive Function
164 Citations (Scopus)

FUS pathology defines the majority of tau-and TDP-43-negative frontotemporal lobar degeneration

Urwin, H., Josephs, K. A., Rohrer, J. D., MacKenzie, I. R., Neumann, M., Authier, A., Seelaar, H., Van Swieten, J. C., Brown, J. M., Johannsen, P., Nielsen, J. E., Holm, I. E., Dickson, D. W., Rademakers, R. V., Graff Radford, N. R., Parisi, J. E., Petersen, R. C., Hatanpaa, K. J., White, C. L., Weiner, M. F. & 27 others, Geser, F., Van Deerlin, V. M., Trojanowski, J. Q., Miller, B. L., Seeley, W. W., Van Der Zee, J., Kumar-Singh, S., Engelborghs, S., De Deyn, P. P., Van Broeckhoven, C., Bigio, E. H., Deng, H. X., Halliday, G. M., Kril, J. J., Munoz, D. G., Mann, D. M., Pickering-Brown, S. M., Doodeman, V., Adamson, G., Ghazi-Noori, S., Fisher, E. M. C., Holton, J. L., Revesz, T., Rossor, M. N., Collinge, J., Mead, S. & Isaacs, A. M., Jul 2010, In : Acta Neuropathologica. 120, 1, p. 33-41 9 p.

Research output: Contribution to journalArticle

Frontotemporal Lobar Degeneration
DNA-Binding Proteins
Sarcoma
Pathology
Multivesicular Bodies
391 Citations (Scopus)

GAB2 Alleles Modify Alzheimer's Risk in APOE ε4 Carriers

Reiman, E. M., Webster, J. A., Myers, A. J., Hardy, J., Dunckley, T., Zismann, V. L., Joshipura, K. D., Pearson, J. V., Hu-Lince, D., Huentelman, MJ., Craig, D. W., Coon, K. D., Liang, W. S., Herbert, R. H., Beach, T., Rohrer, K. C., Zhao, A. S., Leung, D., Bryden, L., Marlowe, L. & 14 others, Kaleem, M., Mastroeni, D., Grover, A., Heward, C. B., Ravid, R., Rogers, J., Hutton, M. L., Melquist, S., Petersen, R. C., Alexander, G. E., Caselli, R. J., Kukull, W., Papassotiropoulos, A. & Stephan, D. A., Jun 7 2007, In : Neuron. 54, 5, p. 713-720 8 p.

Research output: Contribution to journalArticle

Apolipoprotein E4
Carrier Proteins
Alleles
Single Nucleotide Polymorphism
Alzheimer Disease
25 Citations (Scopus)

Gene expression levels as endophenotypes in genome-wide association studies of Alzheimer disease

Zou, F., Carrasquillo, M. M., Pankratz, V. S., Belbin, O., Morgan, K., Allen, M., Wilcox, S. L., Ma, L., Walker, L. P., Kouri, N., Burgess, J. D., Younkin, L. H., Younkin, S. G., Younkin, C. S., Bisceglio, G. D., Crook, J., Dickson, D. W., Petersen, R. C., Graff Radford, N. R., Younkin, S. G. & 1 others, Taner, N., Feb 2010, In : Neurology. 74, 6, p. 480-486 7 p.

Research output: Contribution to journalArticle

Endophenotypes
Genome-Wide Association Study
Insulysin
Alzheimer Disease
Single Nucleotide Polymorphism
5 Citations (Scopus)

Genetically-controlled Vesicle-Associated Membrane Protein 1 expression may contribute to Alzheimer's pathophysiology and susceptibility

Sevlever, D., Zou, F., Ma, L., Carrasquillo, S., Crump, M. G., Culley, O. J., Hunter, T. A., Bisceglio, G. D., Younkin, L., Allen, M., Carrasquillo, M. M., Sando, S. B., Aasly, J. O., Dickson, D. W., Graff Radford, N. R., Petersen, R. C., Morgan, K. & Belbin, O., Apr 9 2015, In : Molecular Neurodegeneration. 10, 1, 18.

Research output: Contribution to journalArticle

Vesicle-Associated Membrane Protein 1
Alzheimer Disease
SNARE Proteins
Memory Disorders
Exocytosis

Genetically elevated high-density lipoprotein cholesterol through the cholesteryl ester transfer protein gene does not associate with risk of Alzheimer's disease

International Genomics of Alzheimer's Project (IGAP), ARUK Consortium & GERAD/PERADES, CHARGE, ADGC, EADI, Jan 1 2018, In : Alzheimer's and Dementia: Diagnosis, Assessment and Disease Monitoring. 10, p. 595-598 4 p.

Research output: Contribution to journalArticle

Cholesterol Ester Transfer Proteins
HDL Cholesterol
Alzheimer Disease
Genes
Single Nucleotide Polymorphism
19 Citations (Scopus)

Genetically predicted body mass index and Alzheimer's disease-related phenotypes in three large samples: Mendelian randomization analyses

Adult Changes in Thought Study Investigators, Religious Orders Study/Memory and Aging Project Investigators & Alzheimer's Disease Genetics Consortium, Dec 1 2015, In : Alzheimer's and Dementia. 11, 12, p. 1439-1451 13 p.

Research output: Contribution to journalArticle

Mendelian Randomization Analysis
Alzheimer Disease
Body Mass Index
Phenotype
Odds Ratio
33 Citations (Scopus)

Genetic architecture of sporadic frontotemporal dementia and overlap with Alzheimer's and Parkinson's diseases

The IFGC and IPDGC members, Feb 1 2017, In : Journal of Neurology, Neurosurgery and Psychiatry. 88, 2, p. 152-164 13 p.

Research output: Contribution to journalArticle

Frontotemporal Dementia
Parkinson Disease
Alzheimer Disease
Genetic Pleiotropy
Single Nucleotide Polymorphism
41 Citations (Scopus)

Genetic meta-analysis of diagnosed Alzheimer’s disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing

Alzheimer Disease Genetics Consortium (ADGC), The European Alzheimer’s Disease Initiative (EADI), Cohorts for Heart and Aging Research in Genomic Epidemiology Consortium (CHARGE), & Genetic and Environmental Risk in AD/Defining Genetic, Polygenic and Environmental Risk for Alzheimer’s Disease Consortium (GERAD/PERADES), Mar 1 2019, In : Nature Genetics. 51, 3, p. 414-430 17 p.

Research output: Contribution to journalArticle

Meta-Analysis
Immunity
Alzheimer Disease
Lipids
Serum Amyloid A Protein
32 Citations (Scopus)

Genetic modifiers in carriers of repeat expansions in the C9ORF72 gene

Van Blitterswijk, M., Mullen, B., Wojtas, A., Heckman, M. G., Diehl, N. N., Baker, M. C., DeJesus-Hernandez, M., Brown, P. H., Murray, M. E., Hsiung, G. Y. R., Stewart, H., Karydas, A. M., Finger, E., Kertesz, A., Bigio, E. H., Weintraub, S., Mesulam, M., Hatanpaa, K. J., White, C. L., Neumann, M. & 19 others, Strong, M. J., Beach, T. G., Wszolek, Z. K., Lippa, C., Caselli, R. J., Petrucelli, L., Josephs, K. A., Parisi, J. E., Knopman, D. S., Petersen, R. C., Mackenzie, I. R., Seeley, W. W., Grinberg, L. T., Miller, B. L., Boylan, K. B., Graff Radford, N. R., Boeve, B. F., Dickson, D. W. & Rademakers, R. V., 2014, In : Molecular Neurodegeneration. 9, p. 38 1 p.

Research output: Contribution to journalArticle

Frontotemporal Dementia
Motor Neuron Disease
Chromosomes, Human, Pair 9
Open Reading Frames
Age of Onset
26 Citations (Scopus)

Genetic risk factors for the posterior cortical atrophy variant of Alzheimer's disease

Schott, J. M., Crutch, S. J., Carrasquillo, M. M., Uphill, J., Shakespeare, T. J., Ryan, N. S., Yong, K. X., Lehmann, M., Taner, N., Graff Radford, N. R., Boeve, B. F., Murray, M. E., Khan, Q. U. A., Petersen, R. C., Dickson, D. W., Knopman, D. S., Rabinovici, G. D., Miller, B. L., González, A. S., Gil-Néciga, E. & 24 others, Snowden, J. S., Harris, J., Pickering-Brown, S. M., Louwersheimer, E., van der Flier, W. M., Scheltens, P., Pijnenburg, Y. A., Galasko, D., Sarazin, M., Dubois, B., Magnin, E., Galimberti, D., Scarpini, E., Cappa, S. F., Hodges, J. R., Halliday, G. M., Bartley, L., Carrillo, M. C., Bras, J. T., Hardy, J., Rossor, M. N., Collinge, J., Fox, N. C. & Mead, S., Aug 1 2016, In : Alzheimer's and Dementia. 12, 8, p. 862-871 10 p.

Research output: Contribution to journalArticle

Atrophy
Alzheimer Disease
Odds Ratio
Genome-Wide Association Study
84 Citations (Scopus)

Genetic Variants in a Haplotype Block Spanning IDE are Significantly Associated with Plasma Aβ42 Levels and Risk for Alzheimer Disease

Taner, N., Allen, M., Fadale, D., Scanlin, L., Younkin, L., Petersen, R. C., Graff Radford, N. R. & Younkin, S. G., 2004, In : Human Mutation. 23, 4, p. 334-342 9 p.

Research output: Contribution to journalArticle

Haplotypes
Alzheimer Disease
Odds Ratio
Phenotype
Chromosomes

Genetic variation in PCDH11X is associated with susceptibility to late onset alzheimer's disease

Carrasquillo, M. M., Zou, F., Pankratz, V. S., Wilcox, S. L., Ma, L., Walker, L. P., Younkin, C. S., Younkin, L. H., Bisceglio, G. D., Taner, N., Crook, J., Dickson, D. W., Petersen, R. C., Graff Radford, N. R. & Younkin, S. G., Jul 8 2010, In : Hirosaki Medical Journal. 61, SUPPL.

Research output: Contribution to journalArticle

Homozygote
Alzheimer Disease
Single Nucleotide Polymorphism
Hemizygote
Alleles
209 Citations (Scopus)

Genetic variation in PCDH11X is associated with susceptibility to late-onset Alzheimer's disease

Carrasquillo, M. M., Zou, F., Pankratz, V. S., Wilcox, S. L., Ma, L., Walker, L. P., Younkin, S. G., Younkin, C. S., Younkin, L. H., Bisceglio, G. D., Taner, N., Crook, J., Dickson, D. W., Petersen, R. C., Graff Radford, N. R. & Younkin, S. G., Feb 2009, In : Nature Genetics. 41, 2, p. 192-198 7 p.

Research output: Contribution to journalArticle

Single Nucleotide Polymorphism
Alzheimer Disease
Hemizygote
Odds Ratio
Genome-Wide Association Study
12 Citations (Scopus)

Genome-wide, high-content siRNA screening identifies the Alzheimer’s genetic risk factor FERMT2 as a major modulator of APP metabolism

ADGC, Alzheimer’s Disease Neuroimaging Initiative, Jun 1 2017, In : Acta Neuropathologica. 133, 6, p. 955-966 12 p.

Research output: Contribution to journalArticle

Small Interfering RNA
Alzheimer Disease
Genome
Genes
Genome-Wide Association Study
6 Citations (Scopus)

Genome-wide analyses as part of the international FTLD-TDP whole-genome sequencing consortium reveals novel disease risk factors and increases support for immune dysfunction in FTLD

Pottier, C., Ren, Y., Perkerson, R. B., Baker, M., Jenkins, G. D., Van Blitterswijk, M., DeJesus-Hernandez, M., van Rooij, J. G. J., Murray, M. E., Christopher, E., McDonnell, S. K., Fogarty, Z., Batzler, A., Tian, S., Vicente, C. T., Matchett, B., Karydas, A. M., Hsiung, G. Y. R., Seelaar, H., Mol, M. O. & 85 others, Finger, E. C., Graff, C., Öijerstedt, L., Neumann, M., Heutink, P., Synofzik, M., Wilke, C., Prudlo, J., Rizzu, P., Simon-Sanchez, J., Edbauer, D., Roeber, S., Diehl-Schmid, J., Evers, B. M., King, A., Mesulam, M. M., Weintraub, S., Geula, C., Bieniek, K. F., Petrucelli, L., Ahern, G. L., Reiman, E. M., Woodruff, B. K., Caselli, R. J., Huey, E. D., Farlow, M. R., Grafman, J., Mead, S., Grinberg, L. T., Spina, S., Grossman, M., Irwin, D. J., Lee, E. B., Suh, E. R., Snowden, J., Mann, D., Taner, N., Uitti, R. J., Wszolek, Z. K., Josephs, K. A., Parisi, J. E., Knopman, D. S., Petersen, R. C., Hodges, J. R., Piguet, O., Geier, E. G., Yokoyama, J. S., Rissman, R. A., Rogaeva, E., Keith, J., Zinman, L., Tartaglia, M. C., Cairns, N. J., Cruchaga, C., Ghetti, B., Kofler, J., Lopez, O. L., Beach, T. G., Arzberger, T., Herms, J., Honig, L. S., Vonsattel, J. P., Halliday, G. M., Kwok, J. B., White, C. L., Gearing, M., Glass, J., Rollinson, S., Pickering-Brown, S., Rohrer, J. D., Trojanowski, J. Q., Van Deerlin, V., Bigio, E. H., Troakes, C., Al-Sarraj, S., Asmann, Y., Miller, B. L., Graff Radford, N. R., Boeve, B. F., Seeley, W. W., Mackenzie, I. R. A., van Swieten, J. C., Dickson, D. W., Biernacka, J. M. & Rademakers, R. V., Jan 1 2019, In : Acta neuropathologica.

Research output: Contribution to journalArticle

Frontotemporal Lobar Degeneration
Frontotemporal Dementia
Genome
Genes
Mutation
779 Citations (Scopus)

Genome-wide analysis of genetic loci associated with Alzheimer disease

Seshadri, S., Fitzpatrick, A. L., Ikram, M. A., DeStefano, A. L., Gudnason, V., Boada, M., Bis, J. C., Smith, A. V., Carassquillo, M. M., Lambert, J. C., Harold, D., Schrijvers, E. M. C., Ramirez-Lorca, R., Debette, S., Longstreth, W. T., Janssens, A. C. J. W., Pankratz, V. S., Dartigues, J. F., Hollingworth, P., Aspelund, T. & 43 others, Hernandez, I., Beiser, A., Kuller, L. H., Koudstaal, P. J., Dickson, D. W., Tzourio, C., Abraham, R., Antunez, C., Du, Y., Rotter, J. I., Aulchenko, Y. S., Harris, T. B., Petersen, R. C., Berr, C., Owen, M. J., Lopez-Arrieta, J., Varadarajan, B. N., Becker, J. T., Rivadeneira, F., Nalls, M. A., Graff Radford, N. R., Campion, D., Auerbach, S., Rice, K., Hofman, A., Jonsson, P. V., Schmidt, H., Lathrop, M., Mosley, T. H., Au, R., Psaty, B. M., Uitterlinden, A. G., Farrer, L. A., Lumley, T., Ruiz, A., Williams, J., Amouyel, P., Younkin, S. G., Wolf, P. A., Launer, L. J., Lopez, O. L., Van Duijn, C. M. & Breteler, M. M. B., May 12 2010, In : JAMA - Journal of the American Medical Association. 303, 18, p. 1832-1840 9 p.

Research output: Contribution to journalArticle

Genetic Loci
Alzheimer Disease
Genome
Genome-Wide Association Study
Single Nucleotide Polymorphism
33 Citations (Scopus)

Genome-wide association interaction analysis for Alzheimer's disease

GERAD1 Consortium, Nov 1 2014, In : Neurobiology of Aging. 35, 11, p. 2436-2443 8 p.

Research output: Contribution to journalArticle

Genome-Wide Association Study
Alzheimer Disease
Gene Expression Profiling
Temporal Lobe
Cerebellum
32 Citations (Scopus)

Genome-wide association study identifies four novel loci associated with Alzheimer’s endophenotypes and disease modifiers

Alzheimer’s Disease Neuroimaging Initiative (ADNI) & The Alzheimer Disease Genetic Consortium (ADGC), May 1 2017, In : Acta Neuropathologica. 133, 5, p. 839-856 18 p.

Research output: Contribution to journalArticle

Endophenotypes
Genome-Wide Association Study
Alzheimer Disease
Cerebrospinal Fluid
Genome
134 Citations (Scopus)

Genome-wide association study of CSF biomarkers Aβ1-42, t-tau, and p-tau181p in the ADNI cohort

Kim, S., Swaminathan, S., Shen, L., Risacher, S. L., Nho, K., Foroud, T., Shaw, L. M., Trojanowski, J. Q., Potkin, S. G., Huentelman, M. J., Craig, D. W., Dechairo, B. M., Aisen, P. S., Petersen, R. C., Weiner, M. W. & Saykin, A. J., Jan 4 2011, In : Neurology. 76, 1, p. 69-79 11 p.

Research output: Contribution to journalArticle

Genome-Wide Association Study
Single Nucleotide Polymorphism
Biomarkers
Genes
Alzheimer Disease
1 Citation (Scopus)

Genome-wide association study of prolactin levels in blood plasma and cerebrospinal fluid

for the Alzheimer's Disease Neuroimaging Initiative, Jun 29 2016, In : BMC Genomics. 17, 436.

Research output: Contribution to journalArticle

Genome-Wide Association Study
Prolactin
Cerebrospinal Fluid
Immune System Phenomena
Single Nucleotide Polymorphism
44 Citations (Scopus)

Genome-wide pathway analysis of memory impairment in the Alzheimer's Disease Neuroimaging Initiative (ADNI) cohort implicates gene candidates, canonical pathways, and networks

Ramanan, V. K., Kim, S., Holohan, K., Shen, L., Nho, K., Risacher, S. L., Foroud, T. M., Mukherjee, S., Crane, P. K., Aisen, P. S., Petersen, R. C., Weiner, M. W. & Saykin, A. J., 2012, In : Brain Imaging and Behavior. 6, 4, p. 634-648 15 p.

Research output: Contribution to journalArticle

Neuroimaging
Alzheimer Disease
Genome
Genes
Memory Disorders
84 Citations (Scopus)

Genome-wide screen identifies rs646776 near sortilin as a regulator of progranulin levels in human plasma

Carrasquillo, M. M., Nicholson, A. M., Finch, N., Gibbs, J. R., Baker, M., Rutherford, N. J., Hunter, T. A., Dejesus-Hernandez, M., Bisceglio, G. D., MacKenzie, I. R., Singleton, A., Cookson, M. R., Crook, J., Dillman, A., Hernandez, D., Petersen, R. C., Graff Radford, N. R., Younkin, S. G. & Rademakers, R. V., Dec 10 2010, In : American Journal of Human Genetics. 87, 6, p. 890-897 8 p.

Research output: Contribution to journalArticle

Single Nucleotide Polymorphism
Genome
Frontotemporal Lobar Degeneration
Neurodegenerative Diseases
Mutation

Glaucoma and dementia: More than meets the eye?

Ward, M. E. & Petersen, R. C., Aug 2013, In : Annals of Neurology. 74, 2, p. 155-157 3 p.

Research output: Contribution to journalArticle

Open Angle Glaucoma
Glaucoma
Dementia
42 Citations (Scopus)

Glutathione S-transferase omega genes in Alzheimer and Parkinson disease risk, age-at-diagnosis and brain gene expression: An association study with mechanistic implications

Allen, M., Zou, F., Chai, H. S., Younkin, C. S., Miles, R., Nair, A. A., Crook, J., Pankratz, V. S., Carrasquillo, M. M., Rowley, C. N., Nguyen, T., Ma, L., Malphrus, K. G., Bisceglio, G., Ortolaza, A. I., Palusak, R., Middha, S., Maharjan, S., Georgescu, C., Schultz, D. & 14 others, Rakhshan, F., Kolbert, C. P., Jen, J., Sando, S. B., Aasly, J. O., Barcikowska, M., Uitti, R. J., Wszolek, Z. K., Ross, O. A., Petersen, R. C., Graff Radford, N. R., Dickson, D. W., Younkin, S. G. & Taner, N., 2012, In : Molecular Neurodegeneration. 7, 1, 13.

Research output: Contribution to journalArticle

Glutathione Transferase
Parkinson Disease
Alzheimer Disease
Gene Expression
Brain
158 Citations (Scopus)

Gray and white matter water diffusion in the syndromic variants of frontotemporal dementia

Whitwell, J. L., Avula, R., Senjem, M. L., Kantarci, K. M., Weigand, S. D., Samikoglu, A., Edmonson, H. A., Vemuri, P. D., Knopman, D. S., Boeve, B. F., Petersen, R. C., Josephs, K. A. & Jack, C. R. J., Apr 2010, In : Neurology. 74, 16, p. 1279-1287 9 p.

Research output: Contribution to journalArticle

Frontotemporal Dementia
Primary Progressive Nonfluent Aphasia
Water
Diffusion Tensor Imaging
Frontal Lobe
6 Citations (Scopus)

Guamanian neurodegenerative disease: Electrophysiologic findings

Ahlskog, J. E., Litchya, W. J., Petersen, R. C., Waring, S. C., Esteban-Santillan, C., Chen, K. M., Harper, C. M., Craig, U. K. & Kurland, L. T., Jun 15 1999, In : Journal of the Neurological Sciences. 166, 1, p. 28-35 8 p.

Research output: Contribution to journalArticle

Neurodegenerative Diseases
Amyotrophic Lateral Sclerosis
Parkinsonian Disorders
Somatosensory Evoked Potentials
Dementia
42 Citations (Scopus)

Guamanian neurodegenerative disease: Investigation of the calcium metabolism/heavy metal hypothesis

Ahlskog, J. E., Waring, S. C., Kurland, L. T., Petersen, R. C., Moyer, T. P., Harmsen, W. S., Maraganore, D. M., O'Brien, P. C., Esteban-Santillan, C. & Bush, V., 1995, In : Neurology. 45, 7, p. 1340-1344 5 p.

Research output: Contribution to journalArticle

Heavy Metals
Neurodegenerative Diseases
Calcium
Guam
Magnesium
8 Citations (Scopus)

Guamanian neurodegenerative disease: Ultrastructural studies of skin

Ono, S., Waring, S. C., Kurland, L. L., Katrina-Craig, U. & Petersen, R. C., Feb 27 1997, In : Journal of the Neurological Sciences. 146, 1, p. 35-40 6 p.

Research output: Contribution to journalArticle

Neurodegenerative Diseases
Amyotrophic Lateral Sclerosis
Parkinsonian Disorders
Skin
Dementia
11 Citations (Scopus)

Guamanian neurodegenerative disease: Are diabetes mellitus and altered humoral immunity clues to pathogenesis?

Ahlskog, J. E., Petersen, R. C., Waring, S. C., Esteban-Santillan, C., Craig, U. K., Maraganore, D. M., Lennon, V. A. & Kurland, L. T., May 1997, In : Neurology. 48, 5, p. 1356-1362 7 p.

Research output: Contribution to journalArticle

Humoral Immunity
Neurodegenerative Diseases
Diabetes Mellitus
Immunoglobulin A
Immunoglobulin G
47 Citations (Scopus)

GWAS of longitudinal amyloid accumulation on 18F-florbetapir PET in Alzheimer's disease implicates microglial activation gene IL1RAP

Ramanan, V. K., Risacher, S. L., Nho, K., Kim, S., Shen, L., McDonald, B. C., Yoder, K. K., Hutchins, G. D., West, J. D., Tallman, E. F., Gao, S., Foroud, T. M., Farlow, M. R., De Jager, P. L., Bennett, D. A., Aisen, P. S., Petersen, R. C., Jack, C. R. J., Toga, A. W., Green, R. C. & 3 others, Jagust, W. J., Weiner, M. W. & Saykin, A. J., Oct 1 2015, In : Brain. 138, 10, p. 3076-3088 13 p.

Research output: Contribution to journalArticle

Genome-Wide Association Study
Amyloid
Transcriptional Activation
Alzheimer Disease
Interleukin-1 Receptor Accessory Protein
27 Citations (Scopus)

Head trauma and in vivo measures of amyloid and neurodegeneration in a population-based study

Mielke, M. M., Savica, R., Wiste, H. J., Weigand, S. D., Vemuri, P. D., Knopman, D. S., Lowe, V., Roberts, R. O., Machulda, M. M., Geda, Y. E., Petersen, R. C. & Jack, C. R. J., Jan 7 2014, In : Neurology. 82, 1, p. 70-76 7 p.

Research output: Contribution to journalArticle

Craniocerebral Trauma
Amyloid
Population
Unconsciousness
Neuroimaging
2 Citations (Scopus)

Heritability and genetic variance of dementia with Lewy bodies

for the International Parkinson's Disease Genomics Consortium, Jul 1 2019, In : Neurobiology of Disease. 127, p. 492-501 10 p.

Research output: Contribution to journalArticle

Lewy Body Disease
Alzheimer Disease
Single Nucleotide Polymorphism
Parkinson Disease
Inborn Genetic Diseases
145 Citations (Scopus)

Higher risk of progression to dementia in mild cognitive impairment cases who revert to normal

Roberts, R. O., Knopman, D. S., Mielke, M. M., Cha, R. H., Pankratz, V. S., Christianson, T. J. H., Geda, Y. E., Boeve, B. F., Ivnik, R. J., Tangalos, E. G., Rocca, W. A. & Petersen, R. C., Jan 28 2014, In : Neurology. 82, 4, p. 317-325 9 p.

Research output: Contribution to journalArticle

Dementia
Cognitive Dysfunction
Mild Cognitive Impairment
Progression
Hazard
16 Citations (Scopus)

High normal fasting blood glucose is associated with dementia in Chinese elderly

Mortimer, J. A., Borenstein, A. R., Ding, D., Decarli, C., Zhao, Q., Copenhaver, C., Guo, Q., Chu, S., Galasko, D., Salmon, D. P., Dai, Q., Wu, Y., Petersen, R. C. & Hong, Z., Nov 2010, In : Alzheimer's and Dementia. 6, 6, p. 440-447 8 p.

Research output: Contribution to journalArticle

Dementia
Blood Glucose
Fasting
Magnetic Resonance Imaging
Education
147 Citations (Scopus)

Hippocampal atrophy and apolipoprotein E genotype are independently associated with Alzheimer's disease

Jack, C. R. J., Petersen, R. C., Xu, Y. C., O'Brien, P. C., Waring, S. C., Tangalos, E. G., Smith, G. E., Ivnik, R. J., Thibodeau, S. N. & Kokmen, E., Mar 1998, In : Annals of Neurology. 43, 3, p. 303-310 8 p.

Research output: Contribution to journalArticle

Apolipoproteins E
Atrophy
Alzheimer Disease
Genotype
Apolipoprotein E4
20 Citations (Scopus)

Hippocampal atrophy correlates with clinical features of Alzheimer disease in African Americans

Sencakova, D., Graff Radford, N. R., Willis, F. B., Lucas, J. A., Parfitt, F., Cha, R. H., O'Brien, P. C., Petersen, R. C. & Jack, C. R. J., 2001, In : Archives of Neurology. 58, 10, p. 1593-1597 5 p.

Research output: Contribution to journalArticle

African Americans
Atrophy
Alzheimer Disease
Healthy Volunteers
Neuropsychological Tests
50 Citations (Scopus)

Hippocampal atrophy rates and CSF biomarkers in elderly APOE2 normal subjects

Chiang, G. C., Insel, P. S., Tosun, D., Schuff, N., Truran-Sacrey, D., Raptentsetsang, S. T., Jack, C. R. J., Aisen, P. S., Petersen, R. C. & Weiner, M. W., Nov 30 2010, In : Neurology. 75, 22, p. 1976-1981 6 p.

Research output: Contribution to journalArticle

Atrophy
Biomarkers
Confidence Intervals
Pathology
Episodic Memory
26 Citations (Scopus)

Hippocampal transverse relaxation times in patients with Alzheimer disease

Campeau, N. G., Petersen, R. C., Felmlee, J. P., O'Brien, P. C. & Jack, C. R. J., Oct 1997, In : Radiology. 205, 1, p. 197-201 5 p.

Research output: Contribution to journalArticle

Alzheimer Disease
Dementia
Hippocampus
Head
Magnetic Resonance Imaging
55 Citations (Scopus)

Hippocampal Volume Is Associated with Memory but not Nonmemory Cognitive Performance in Patients with Mild Cognitive Impairment

Grundman, M., Jack, C. R. J., Petersen, R. C., Kim, H. T., Taylor, C., Datvian, M., Weiner, M. F., DeCarli, C., DeKosky, S. J., Van Dyck, C., Darvesh, S., Yaffe, K., Kaye, J., Ferris, S. H., Thomas, R. G. & Thal, L. J., 2003, In : Journal of Molecular Neuroscience. 20, 3, p. 241-248 8 p.

Research output: Contribution to journalArticle

Alzheimer Disease
Data storage equipment
Atrophy
Pathology
Cognitive Dysfunction
64 Citations (Scopus)

Hippocampal volumes, proton magnetic resonance spectroscopy metabolites, and cerebrovascular disease in mild cognitive impairment subtypes

Kantarci, K. M., Petersen, R. C., Przybelski, S. A., Weigand, S. D., Shiung, M. M., Whitwell, J. L., Negash, S., Ivnik, R. J., Boeve, B. F., Knopman, D. S., Smith, G. E. & Jack, C. R. J., Dec 2008, In : Archives of Neurology. 65, 12, p. 1621-1628 8 p.

Research output: Contribution to journalArticle

Cerebrovascular Disorders
Magnetic Resonance Imaging
Alzheimer Disease
Proton Magnetic Resonance Spectroscopy
Cognitive Dysfunction
14 Citations (Scopus)

Hippocampal volumes predict risk of dementia with Lewy bodies in mild cognitive impairment

Kantarci, K. M., Lesnick, T., Ferman, T. J., Przybelski, S. A., Boeve, B. F., Smith, G. E., Kremers, W. K., Knopman, D. S., Jack, C. R. J. & Petersen, R. C., Nov 29 2016, In : Neurology. 87, 22, p. 2317-2323 7 p.

Research output: Contribution to journalArticle

Lewy Body Disease
Alzheimer Disease
Atrophy
Cognitive Dysfunction
27 Citations (Scopus)

HMGCR is a genetic modifier for risk, age of onset and MCI conversion to Alzheimer's disease in a three cohorts study

Leduc, V., De Beaumont, L., Théroux, L., Dea, D., Aisen, P., Petersen, R. C., Dufour, R. & Poirier, J., Jul 24 2015, In : Molecular Psychiatry. 20, 7, p. 867-873 7 p.

Research output: Contribution to journalArticle

Coenzyme A
Age of Onset
Alzheimer Disease
Oxidoreductases
Cohort Studies
4 Citations (Scopus)

How can we best categorize cognitive impairment in nondemented older adults?

Sachdev, P. S., Ganguli, M. & Petersen, R. C., Aug 2010, In : American Journal of Geriatric Psychiatry. 18, 8, p. 657-661 5 p.

Research output: Contribution to journalArticle

Cognitive Dysfunction
8 Citations (Scopus)

How early can we diagnose Alzheimer disease (and is it sufficient)?

Petersen, R. C., Aug 28 2018, In : Neurology. 91, 9, p. 395-402 8 p.

Research output: Contribution to journalArticle

Early Diagnosis
Alzheimer Disease
Aptitude
Dementia
Pathology

Human state-dependent learning processes involving scopolamine

Petersen, R. C., 1977, In : Federation Proceedings. 36, 3

Research output: Contribution to journalArticle

Scopolamine Hydrobromide
Learning