Ronald Carl Petersen, MD &ndash; Research Output

2018

[¹⁸F]AV-1451 tau-PET and primary progressive aphasia

Josephs, K. A., Martin, P. R., Botha, H., Schwarz, C., Duffy, J. R., Clark, H., Machulda, M. M., Graff-Radford, J., Weigand, S. D., Senjem, M. L., Utianski, R., Drubach, D., Boeve, B. F., Jones, D. T., Knopman, D. S., Petersen, R. C., Jack, C. R. J., Lowe, V. & Whitwell, J. L., Jan 1 2018, (Accepted/In press) In : Annals of Neurology.

Research output: Contribution to journal › Article

Primary Progressive Aphasia

Semantics

Principal Component Analysis

4 Citations (Scopus)

[¹⁸F] AV-1451 uptake in corticobasal syndrome: the influence of beta-amyloid and clinical presentation

Ali, F., Whitwell, J. L., Martin, P. R., Senjem, M. L., Knopman, D. S., Jack, C. R. J., Lowe, V., Petersen, R. C., Boeve, B. F. & Josephs, K. A., Mar 1 2018, (Accepted/In press) In : Journal of Neurology. p. 1-10 10 p.

Research output: Contribution to journal › Article

Amyloid

Apraxias

Alzheimer Disease

Tauopathies

Pathology

5 Citations (Scopus)

¹⁸F-FDG PET-CT pattern in idiopathic normal pressure hydrocephalus

Townley, R. A., Botha, H., Graff-Radford, J., Boeve, B. F., Petersen, R. C., Senjem, M. L., Knopman, D. S., Lowe, V., Jack, C. R. J. & Jones, D. T., Jan 1 2018, In : NeuroImage: Clinical. 18, p. 897-902 6 p.

Research output: Contribution to journal › Article

Normal Pressure Hydrocephalus

Fluorodeoxyglucose F18

Dementia

Alzheimer Disease

Frontotemporal Dementia

2 Citations (Scopus)

ABI3 and PLCG2 missense variants as risk factors for neurodegenerative diseases in Caucasians and African Americans 11 Medical and Health Sciences 1109 Neurosciences 06 Biological Sciences 0604 Genetics

Conway, O. J., Carrasquillo, M. M., Wang, X., Bredenberg, J. M., Reddy, J. S., Strickland, S. L., Younkin, C. S., Burgess, J. D., Allen, M., Lincoln, S. J., Nguyen, T., Malphrus, K. G., Soto, A. I., Walton, R. L., Boeve, B. F., Petersen, R. C., Lucas, J. A., Ferman, T. J., Cheshire, W. P., Van Gerpen, J. A. & 6 others, Uitti, R. J., Wszolek, Z. K., Ross, O. A., Dickson, D. W., Graff Radford, N. R. & Taner, N., Oct 11 2018, In : Molecular Neurodegeneration. 13, 1, 53.

Research output: Contribution to journal › Article

Biological Science Disciplines

Neurosciences

Neurodegenerative Diseases

African Americans

Alzheimer Disease

6 Citations (Scopus)

A C6orf10/LOC101929163 locus is associated with age of onset in C9orf72 carriers

Zhang, M., Ferrari, R., Tartaglia, M. C., Keith, J., Surace, E. I., Wolf, U., Sato, C., Grinberg, M., Liang, Y., Xi, Z., Dupont, K., McGoldrick, P., Weichert, A., McKeever, P. M., Schneider, R., McCorkindale, M. D., Manzoni, C., Rademakers, R. V., Graff Radford, N. R., Dickson, D. W. & 60 others, Parisi, J. E., Boeve, B. F., Petersen, R. C., Miller, B. L., Seeley, W. W., Van Swieten, J. C., Van Rooij, J., Pijnenburg, Y., Van Der Zee, J., Van Broeckhoven, C., Le Ber, I., Van Deerlin, V., Suh, E. R., Rohrer, J. D., Mead, S., Graff, C., Öijerstedt, L., Pickering-Brown, S., Rollinson, S., Rossi, G., Tagliavini, F., Brooks, W. S., Dobson-Stone, C., Halliday, G. M., Hodges, J. R., Piguet, O., Binetti, G., Benussi, L., Ghidoni, R., Nacmias, B., Sorbi, S., Bruni, A. C., Galimberti, D., Scarpini, E., Rainero, I., Rubino, E., Clarimon, J., Lleó, A., Ruiz, A., Hernández, I., Pastor, P., Diez-Fairen, M., Borroni, B., Pasquier, F., Deramecourt, V., Lebouvier, T., Perneczky, R., Diehl-Schmid, J., Grafman, J., Huey, E. D., Mayeux, R., Nalls, M. A., Hernandez, D., Singleton, A., Momeni, P., Zeng, Z., Hardy, J., Robertson, J., Zinman, L. & Rogaeva, E., Oct 1 2018, In : Brain. 141, 10, p. 2895-2907 13 p.

Research output: Contribution to journal › Article

Age of Onset

DNA Methylation

HLA-DRB1 Chains

Alleles

Single Nucleotide Polymorphism

Amyloid- and tau-PET imaging in a familial prion kindred

Jones, D. T., Townley, R. A., Graff-Radford, J., Botha, H., Knopman, D. S., Petersen, R. C., Jack, C. R. J., Lowe, V. & Boeve, B. F., Dec 1 2018, In : Neurology: Genetics. 4, 6, e290.

Research output: Contribution to journal › Article

Prions

Amyloid

Alzheimer Disease

Neurobiology

Amyloid Plaques

14 Citations (Scopus)

APOE ε4 is associated with severity of Lewy body pathology independent of Alzheimer pathology

Dickson, D. W., Heckman, M. G., Murray, M. E., Soto, A. I., Walton, R. L., Diehl, N. N., Van Gerpen, J. A., Uitti, R. J., Wszolek, Z. K., Taner, N., Knopman, D. S., Petersen, R. C., Graff Radford, N. R., Boeve, B. F., Bu, G. D., Ferman, T. J. & Ross, O. A., Sep 18 2018, In : Neurology. 91, 12, p. e1182-e1195

Research output: Contribution to journal › Article

Lewy Bodies

Pathology

Alzheimer Disease

Dementia

Odds Ratio

10 Citations (Scopus)

Association between exposure to anaesthesia and surgery and long-term cognitive trajectories in older adults: report from the Mayo Clinic Study of Aging

Schulte, P., Roberts, R. O., Knopman, D. S., Petersen, R. C., Hanson, A. C., Schroeder, D. R., Weingarten, T. N., Martin, D. P., Warner, D. O. & Sprung, J., Aug 1 2018, In : British Journal of Anaesthesia. 121, 2, p. 398-405 8 p.

Research output: Contribution to journal › Article

Anesthesia

Cognition

General Anesthesia

Confidence Intervals

Cognitive Dysfunction

2 Citations (Scopus)

Association Between Functional Performance and Alzheimer's Disease Biomarkers in Individuals Without Dementia

Vassilaki, M., Aakre, J. A., Kremers, W. K., Mielke, M. M., Geda, Y. E., Machulda, M. M., Knopman, D. S., Coloma, P. M., Schauble, B., Vemuri, P. D., Lowe, V., Jack, C. R. J., Petersen, R. C. & Roberts, R. O., Dec 1 2018, In : Journal of the American Geriatrics Society. 66, 12, p. 2274-2281 8 p.

Research output: Contribution to journal › Article

Dementia

Alzheimer Disease

Biomarkers

Amyloid

Neuroimaging

8 Citations (Scopus)

Association between microinfarcts and blood pressure trajectories

Graff-Radford, J., Raman, M. R., Rabinstein, A., Przybelski, S. A., Lesnick, T. G., Boeve, B. F., Murray, M. E., Dickson, D. W., Ross Reichard, R., Parisi, J. E., Knopman, D. S., Petersen, R. C., Jack, C. R. J. & Kantarci, K. M., Feb 1 2018, In : JAMA Neurology. 75, 2, p. 212-218 7 p.

Research output: Contribution to journal › Article

Blood Pressure

Autopsy

Cohort Studies

Logistic Models

Regression Analysis

4 Citations (Scopus)

Association of antidiabetic medication use, cognitive decline, and risk of cognitive impairment in older people with type 2 diabetes: Results from the population-based Mayo Clinic Study of Aging

Wennberg, A. M. V., Hagen, C. E., Edwards, K., Roberts, R. O., Machulda, M. M., Knopman, D. S., Petersen, R. C. & Mielke, M. M., Aug 1 2018, In : International Journal of Geriatric Psychiatry. 33, 8, p. 1114-1120 7 p.

Research output: Contribution to journal › Article

Metformin

Hypoglycemic Agents

Type 2 Diabetes Mellitus

Population

Propensity Score

7 Citations (Scopus)

Association of Apolipoprotein e ϵ4 with Transactive Response DNA-Binding Protein 43

Wennberg, A. M., Tosakulwong, N., Lesnick, T. G., Murray, M. E., Whitwell, J. L., Liesinger, A. M., Petrucelli, L., Boeve, B. F., Parisi, J. E., Knopman, D. S., Petersen, R. C., Dickson, D. W. & Josephs, K. A., Jan 1 2018, (Accepted/In press) In : JAMA Neurology. p. E1-E8

Research output: Contribution to journal › Article

Apolipoproteins

DNA-Binding Proteins

Apolipoprotein E4

Alzheimer Disease

Apolipoproteins E

4 Citations (Scopus)

Association of Bilateral Salpingo-Oophorectomy before Menopause Onset with Medial Temporal Lobe Neurodegeneration

Zeydan, B., Tosakulwong, N., Schwarz, C., Senjem, M. L., Gunter, J. L., Reid, R. I., Gazzuola Rocca, L., Lesnick, T. G., Smith, C. Y., Bailey, K. R., Lowe, V., Roberts, R. O., Jack, C. R. J., Petersen, R. C., Miller, V. M., Mielke, M. M., Rocca, W. A. & Kantarci, K. M., Jan 1 2018, (Accepted/In press) In : JAMA Neurology.

Research output: Contribution to journal › Article

Ovariectomy

Temporal Lobe

Menopause

Control Groups

Anisotropy

2 Citations (Scopus)

Association of Cerebrospinal Fluid Neurofilament Light Protein with Risk of Mild Cognitive Impairment among Individuals Without Cognitive Impairment

Kern, S., Syrjanen, J. A., Blennow, K., Zetterberg, H., Skoog, I., Waern, M., Hagen, C. E., Van Harten, A. C., Knopman, D. S., Jack, C. R. J., Petersen, R. C. & Mielke, M. M., Jan 1 2018, (Accepted/In press) In : JAMA Neurology.

Research output: Contribution to journal › Article

Cerebrospinal Fluid Proteins

Intermediate Filaments

Cerebrospinal Fluid

Light

Neurogranin

26 Citations (Scopus)

Association of excessive daytime sleepiness with longitudinal β-Amyloid accumulation in elderly persons without dementia

Carvalho, D. Z., St Louis, E. K., Knopman, D. S., Boeve, B. F., Lowe, V., Roberts, R. O., Mielke, M. M., Przybelski, S. A., Machulda, M. M., Petersen, R. C., Jack, C. R. J. & Vemuri, P. D., Jun 1 2018, In : JAMA Neurology. 75, 6, p. 672-680 9 p.

Research output: Contribution to journal › Article

Gyrus Cinguli

Amyloid

Dementia

Parietal Lobe

Sleep

5 Citations (Scopus)

Association of telomere length with general cognitive trajectories: a meta-analysis of four prospective cohort studies

Zhan, Y., Clements, M. S., Roberts, R. O., Vassilaki, M., Druliner, B. R., Boardman, L. A., Petersen, R. C., Reynolds, C. A., Pedersen, N. L. & Hägg, S., Sep 1 2018, In : Neurobiology of Aging. 69, p. 111-116 6 p.

Research output: Contribution to journal › Article

Aptitude

Telomere

Meta-Analysis

Cohort Studies

Prospective Studies

4 Citations (Scopus)

Author response: Practice guideline update summary: Mild cognitive impairment: Report of the Guideline Development, Dissemination, and Implementation Subcommittee of the American Academy of Neurology

Petersen, R. C., Lopez, O., Armstrong, M. J., Getchius, T. S. D., Ganguli, M., Gloss, D., Gronseth, G. S., Marson, D., Pringsheim, T., Day, G. S., Sager, M., Stevens, J. & Rae-Grant, A., Aug 21 2018, In : Neurology. 91, 8, p. 373-374 2 p.

Research output: Contribution to journal › Comment/debate

Practice Guidelines

Guidelines

Cognitive Dysfunction

Automated and manual hippocampal segmentation techniques: Comparison of results, reproducibility and clinical applicability

Hurtz, S., Chow, N., Watson, A. E., Somme, J. H., Goukasian, N., Hwang, K. S., Morra, J., Elashoff, D., Gao, S., Petersen, R. C., Aisen, P. S., Thompson, P. M. & Apostolova, L. G., Jan 1 2018, (Accepted/In press) In : NeuroImage: Clinical. 101574.

Research output: Contribution to journal › Article

Reproducibility of Results

Atrophy

Alzheimer Disease

Aptitude

Vitamin E

Automated detection of imaging features of disproportionately enlarged subarachnoid space hydrocephalus using machine learning methods

Gunter, N. B., Schwarz, C., Graff-Radford, J., Gunter, J. L., Jones, D. T., Graff Radford, N. R., Petersen, R. C., Knopman, D. S. & Jack, C. R. J., Jan 1 2018, (Accepted/In press) In : NeuroImage: Clinical.

Research output: Contribution to journal › Article

Subarachnoid Space

Hydrocephalus

Cerebrospinal Fluid

ROC Curve

Normal Pressure Hydrocephalus

14 Citations (Scopus)

Brain multiplexes reveal morphological connectional biomarkers fingerprinting late brain dementia states

Mahjoub, I., Mahjoub, M. A., Rekik, I., Weiner, M., Aisen, P., Petersen, R. C., Jack, C. R. J., Jagust, W., Trojanowki, J., Toga, A., Beckett, L., Green, R., Saykin, A., Morris, J., Shaw, L., Kaye, J., Quinn, J., Silbert, L., Lind, B., Carter, R. & 221 others, Dolen, S., Schneider, L., Pawluczyk, S., Beccera, M., Teodoro, L., Spann, B., Brewer, J., Vanderswag, H., Fleisher, A., Heidebrink, J., Lord, J., Mason, S., Albers, C., Knopman, D. S., Johnson, K., Doody, R., Villanueva-Meyer, J., Chowdhury, M., Rountree, S., Dang, M., Stern, Y., Honig, L., Bell, K., Ances, B., Carroll, M., Creech, M., Franklin, E., Mintun, M., Schneider, S., Oliver, A., Marson, D., Grifth, R., Clark, D., Geldmacher, D., Brockington, J., Roberson, E., Natelson Love, M., Grossman, H., Mitsis, E., Shah, R., Detoledo-Morrell, L., Duara, R., Varon, D., Greig, M., Roberts, P., Albert, M., Onyike, C., D'Agostino, D., Kielb, S., Galvin, J., Cerbone, B., Michel, C., Pogorelec, D., Rusinek, H., De Leon, M., Glodzik, L., De Santi, S., Doraiswamy, P., Petrella, J., Borges-Neto, S., Wong, T., Coleman, E., Smith, C., Jicha, G., Hardy, P., Sinha, P., Oates, E., Conrad, G., Porsteinsson, A., Goldstein, B., Martin, K., Makino, K., Ismail, M., Brand, C., Mulnard, R., Thai, G., Mc-Adams-Ortiz, C., Womack, K., Mathews, D., Quiceno, M., Levey, A., Lah, J., Cellar, J., Burns, J., Swerdlow, R., Brooks, W., Apostolova, L., Tingus, K., Woo, E., Silverman, D., Lu, P., Bartzokis, G., Graf-Radford, N., Parftt, F., Kendall, T., Johnson, H., Farlow, M., Hake, A. M., Matthews, B., Brosch, J., Herring, S., Hunt, C., Dyck, C., Carson, R., MacAvoy, M., Varma, P., Chertkow, H., Bergman, H., Hosein, C., Black, S., Stefanovic, B., Caldwell, C., Robin Hsiung, G. Y., Feldman, H., Mudge, B., Assaly, M., Finger, E., Pasternack, S., Rachisky, I., Trost, D., Kertesz, A., Bernick, C., Munic, D., Mesulam, M. M., Lipowski, K., Weintraub, S., Bonakdarpour, B., Kerwin, D., Wu, C. K., Johnson, N., Sadowsky, C., Villena, T., Turner, R. S., Johnson, K., Reynolds, B., Sperling, R., Johnson, K., Marshall, G., Yesavage, J., Taylor, J., Lane, B., Rosen, A., Tinklenberg, J., Sabbagh, M., Belden, C., Jacobson, S., Sirrel, S., Kowall, N., Killiany, R., Budson, A., Norbash, A., Johnson, P. L., Obisesan, T., Wolday, S., Allard, J., Lerner, A., Ogrocki, P., Tatsuoka, C., Fatica, P., Fletcher, E., Maillard, P., Olichney, J., Decarli, C., Carmichael, O., Kittur, S., Borrie, M., Lee, T. Y., Bartha, R., Johnson, S., Asthana, S., Carlsson, C., Potkin, S., Preda, A., Nguyen, D., Tariot, P., Burke, A., Trncic, N., Reeder, S., Bates, V., Capote, H., Rainka, M., Scharre, D., Kataki, M., Adeli, A., Zimmerman, E., Celmins, D., Brown, A., Pearlson, G., Blank, K., Anderson, K., Flashman, L., Seltzer, M., Hynes, M., Santulli, R., Sink, K., Gordineer, L., Williamson, J., Garg, P., Watkins, F., Ott, B., Querfurth, H., Tremont, G., Salloway, S., Malloy, P., Correia, S., Rosen, H., Miller, B., Perry, D., Mintzer, J., Spicer, K., Bachman, D., Pomara, N., Hernando, R., Sarrael, A., Relkin, N., Chaing, G., Lin, M., Ravdin, L., Smith, A., Raj, B. A. & Fargher, K., Dec 1 2018, In : Scientific Reports. 8, 1, 4103.

Research output: Contribution to journal › Article

Biomarkers

Brain

Patient treatment

Electric network analysis

Magnetic resonance imaging

20 Citations (Scopus)

Cellular senescence in brain aging and neurodegenerative diseases: Evidence and perspectives

Baker, D. J. & Petersen, R. C., Apr 2 2018, In : Journal of Clinical Investigation. 128, 4, p. 1208-1216 9 p.

Research output: Contribution to journal › Review article

Cell Aging

Brain Diseases

Neurodegenerative Diseases

Cell Cycle Checkpoints

Parkinson Disease

1 Citation (Scopus)

Characteristic patterns of inter- and intra-hemispheric metabolic connectivity in patients with stable and progressive mild cognitive impairment and Alzheimer’s disease

For the Alzheimer’s Disease Neuroimaging Initiative, Dec 1 2018, In : Scientific Reports. 8, 1, 13807.

Research output: Contribution to journal › Article

Alzheimer Disease

Metabolic Networks and Pathways

Brain

Fluorodeoxyglucose F18

Occipital Lobe

1 Citation (Scopus)

Clinicopathological and ¹²³I-FP-CIT SPECT correlations in patients with dementia

Jung, Y., Jordan, L. G., Lowe, V., Kantarci, K. M., Parisi, J. E., Dickson, D. W., Murray, M. E., Reichard, R. R., Ferman, T. J., Jones, D. T., Graff-Radford, J., Savica, R., Machulda, M. M., Fields, J. A., Allen, L. A., Drubach, D., St Louis, E. K., Silber, M. H., Jack, C. R. J., Knopman, D. S. & 2 others, Petersen, R. C. & Boeve, B. F., Jan 1 2018, (Accepted/In press) In : Annals of Clinical and Translational Neurology.

Research output: Contribution to journal › Article

Lewy Body Disease

Single-Photon Emission-Computed Tomography

Dementia

Corpus Striatum

Putamen

Comparison of PC and iPad administrations of the Cogstate Brief Battery in the Mayo Clinic Study of Aging: assessing cross-modality equivalence of computerized neuropsychological tests

Stricker, N., Lundt, E. S., Edwards, K. K., Machulda, M. M., Kremers, W. K., Roberts, R. O., Knopman, D. S., Petersen, R. C. & Mielke, M. M., Jan 1 2018, (Accepted/In press) In : Clinical Neuropsychologist.

Research output: Contribution to journal › Article

Neuropsychological Tests

Microcomputers

Maze Learning

Equivalence

Battery

10 Citations (Scopus)

CXCR4 involvement in neurodegenerative diseases

International FTD-Genomics Consortium (IFGC), International Parkinson's Disease Genetics Consortium (IPDGC), International Genomics of Alzheimer's Project (IGAP), Dec 1 2018, In : Translational Psychiatry. 8, 1, 73.

Research output: Contribution to journal › Article

Progressive Supranuclear Palsy

Neurodegenerative Diseases

Parkinson Disease

Frontotemporal Dementia

Brain

3 Citations (Scopus)

Development of a cerebrovascular magnetic resonance imaging biomarker for cognitive aging

Vemuri, P. D., Lesnick, T. G., Przybelski, S. A., Graff-Radford, J., Reid, R. I., Lowe, V., Zuk, S. M., Senjem, M. L., Schwarz, C., Gunter, J. L., Kantarci, K. M., Machulda, M. M., Mielke, M. M., Petersen, R. C., Knopman, D. S. & Jack, C. R. J., Jan 1 2018, (Accepted/In press) In : Annals of Neurology.

Research output: Contribution to journal › Article

Biomarkers

Magnetic Resonance Imaging

Health

Blood Vessels

Amyloid

1 Citation (Scopus)

Disrupted functional connectivity in primary progressive apraxia of speech

Botha, H., Utianski, R., Whitwell, J. L., Duffy, J. R., Clark, H., Strand, E. A., Machulda, M. M., Tosakulwong, N., Knopman, D. S., Petersen, R. C., Jack, C. R. J., Josephs, K. A. & Jones, D. T., Jan 1 2018, In : NeuroImage: Clinical. 18, p. 617-629 13 p.

Research output: Contribution to journal › Article

Apraxias

Motor Cortex

Language

Short-Term Memory

Speech Disorders

3 Citations (Scopus)

Effect of Cognitive Status on the Receipt of Procedures Requiring Anesthesia and Critical Care Admissions in Older Adults

Schulte, P., Martin, D. P., Deljou, A., Sabov, M., Roberts, R. O., Knopman, D. S., Petersen, R. C., Weingarten, T. N., Hanson, A. C., Schroeder, D. R., Warner, D. O. & Sprung, J., Jan 1 2018, (Accepted/In press) In : Mayo Clinic Proceedings.

Research output: Contribution to journal › Article

Critical Care

Dementia

Anesthesia

Intensive Care Units

Cognitive Dysfunction

3 Citations (Scopus)

Elevated medial temporal lobe and pervasive brain tau-PET signal in normal participants

Lowe, V., Bruinsma, T. J., Min, H. K., Lundt, E. S., Fang, P., Senjem, M. L., Boeve, B. F., Josephs, K. A., Pandey, M., Murray, M. E., Kantarci, K. M., Jones, D. T., Schwarz, C., Knopman, D. S., Petersen, R. C. & Jack, C. R. J., Jan 1 2018, In : Alzheimer's and Dementia: Diagnosis, Assessment and Disease Monitoring. 10, p. 210-216 7 p.

Research output: Contribution to journal › Article

Temporal Lobe

Alzheimer Disease

Brain

Neurofibrillary Tangles

Tomography

7 Citations (Scopus)

FDG-PET in tau-negative amnestic dementia resembles that of autopsy-proven hippocampal sclerosis

Botha, H., Mantyh, W. G., Murray, M. E., Knopman, D. S., Przybelski, S. A., Wiste, H. J., Graff-Radford, J., Josephs, K. A., Schwarz, C., Kremers, W. K., Boeve, B. F., Petersen, R. C., Machulda, M. M., Parisi, J. E., Dickson, D. W., Lowe, V., Jack, C. R. J. & Jones, D. T., Apr 1 2018, In : Brain. 141, 4, p. 1201-1217 17 p.

Research output: Contribution to journal › Article

Sclerosis

Dementia

Autopsy

Amyloid

Fluorodeoxyglucose F18

1 Citation (Scopus)

Frequency of Acute and Subacute Infarcts in a Population-Based Study

Arnold Fiebelkorn, C., Vemuri, P. D., Rabinstein, A., Mielke, M. M., Przybelski, S. A., Kantarci, K. M., Jones, D. T., Brown, R. D. J., Knopman, D. S., Petersen, R. C., Jack, C. R. J. & Graff-Radford, J., Mar 1 2018, In : Mayo Clinic Proceedings. 93, 3, p. 300-306 7 p.

Research output: Contribution to journal › Article

Cerebral Infarction

Population

Magnetic Resonance Imaging

Diffusion Tensor Imaging

Incidental Findings

Functional Activity and Neuropsychiatric Symptoms in Normal Aging and Mild Cognitive Impairment: The Mayo Clinic Study of Aging

Krell-Roesch, J., Cerhan, L. P., Machulda, M. M., Roberts, R. O., Mielke, M. M., Knopman, D. S., Syrjanen, J. A., Christianson, T. J., Petersen, R. C. & Geda, Y. E., Jan 1 2018, (Accepted/In press) In : Alzheimer Disease and Associated Disorders.

Research output: Contribution to journal › Article

Case-Control Studies

Cognitive Dysfunction

Genetically elevated high-density lipoprotein cholesterol through the cholesteryl ester transfer protein gene does not associate with risk of Alzheimer's disease

International Genomics of Alzheimer's Project (IGAP), ARUK Consortium & GERAD/PERADES, CHARGE, ADGC, EADI, Jan 1 2018, In : Alzheimer's and Dementia: Diagnosis, Assessment and Disease Monitoring. 10, p. 595-598 4 p.

Research output: Contribution to journal › Article

Cholesterol Ester Transfer Proteins

HDL Cholesterol

Alzheimer Disease

Genes

Single Nucleotide Polymorphism

7 Citations (Scopus)

How early can we diagnose Alzheimer disease (and is it sufficient)?

Petersen, R. C., Aug 28 2018, In : Neurology. 91, 9, p. 395-402 8 p.

Research output: Contribution to journal › Article

Early Diagnosis

Alzheimer Disease

Aptitude

Dementia

Pathology

11 Citations (Scopus)

Imaging correlations of tau, amyloid, metabolism, and atrophy in typical and atypical Alzheimer's disease

Whitwell, J. L., Graff-Radford, J., Tosakulwong, N., Weigand, S. D., Machulda, M. M., Senjem, M. L., Spychalla, A. J., Vemuri, P. D., Jones, D. T., Drubach, D., Knopman, D. S., Boeve, B. F., Taner, N., Petersen, R. C., Lowe, V., Jack, C. R. J. & Josephs, K. A., Jan 1 2018, (Accepted/In press) In : Alzheimer's and Dementia.

Research output: Contribution to journal › Article

Amyloid

Positron-Emission Tomography

Atrophy

Alzheimer Disease

Neuroimaging

21 Citations (Scopus)

Immune-related genetic enrichment in frontotemporal dementia: An analysis of genome-wide association studies

International FTD-Genomics Consortium, Jan 1 2018, In : PLoS Medicine. 15, 1, e1002487.

Research output: Contribution to journal › Article

Frontotemporal Dementia

Genome-Wide Association Study

Immune System Diseases

HLA Antigens

Progressive Supranuclear Palsy

43 Citations (Scopus)

Investigating the genetic architecture of dementia with Lewy bodies: a two-stage genome-wide association study

Guerreiro, R., Ross, O. A., Kun-Rodrigues, C., Hernandez, D. G., Orme, T., Eicher, J. D., Shepherd, C. E., Parkkinen, L., Darwent, L., Heckman, M. G., Scholz, S. W., Troncoso, J. C., Pletnikova, O., Ansorge, O., Clarimon, J., Lleo, A., Morenas-Rodriguez, E., Clark, L., Honig, L. S., Marder, K. & 45 others, Lemstra, A., Rogaeva, E., St George-Hyslop, P., Londos, E., Zetterberg, H., Barber, I., Braae, A., Brown, K., Morgan, K., Troakes, C., Al-Sarraj, S., Lashley, T., Holton, J., Compta, Y., Van Deerlin, V., Serrano, G. E., Beach, T. G., Lesage, S., Galasko, D., Masliah, E., Santana, I., Pastor, P., Diez-Fairen, M., Aguilar, M., Tienari, P. J., Myllykangas, L., Oinas, M., Revesz, T., Lees, A., Boeve, B. F., Petersen, R. C., Ferman, T. J., Escott-Price, V., Graff Radford, N. R., Cairns, N. J., Morris, J. C., Pickering-Brown, S., Mann, D., Halliday, G. M., Hardy, J., Trojanowski, J. Q., Dickson, D. W., Singleton, A., Stone, D. J. & Bras, J., Jan 1 2018, In : The Lancet Neurology. 17, 1, p. 64-74 11 p.

Research output: Contribution to journal › Article

Lewy Body Disease

Genome-Wide Association Study

Odds Ratio

Dementia

Lewy Bodies

11 Citations (Scopus)

In vivo ¹⁸F-AV-1451 tau PET signal in MAPT mutation carriers varies by expected tau isoforms

Jones, D. T., Knopman, D. S., Graff-Radford, J., Syrjanen, J. A., Senjem, M. L., Schwarz, C., Dheel, C., Wszolek, Z. K., Rademakers, R. V., Kantarci, K. M., Petersen, R. C., Jack, C. R. J., Lowe, V. & Boeve, B. F., Mar 13 2018, In : Neurology. 90, 11, p. e947-e954

Research output: Contribution to journal › Article

Microtubule-Associated Proteins

Protein Isoforms

Mutation

Exons

Alzheimer Disease

11 Citations (Scopus)

Japanese and North American Alzheimer's Disease Neuroimaging Initiative studies: Harmonization for international trials

Japanese Alzheimer's Disease Neuroimaging Initiative & Alzheimer's Disease Neuroimaging Initiative, Jan 1 2018, (Accepted/In press) In : Alzheimer's and Dementia.

Research output: Contribution to journal › Article

Neuroimaging

Alzheimer Disease

Amyloid

Cognition

Western Asia

7 Citations (Scopus)