• 114774 Citations
  • 149 Scopus h-Index
1974 …2019
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Research Output 1974 2019

2017
16 Citations (Scopus)

Targeted neurogenesis pathway-based gene analysis identifies ADORA2A associated with hippocampal volume in mild cognitive impairment and Alzheimer's disease

Alzheimer's Disease Neuroimaging Initiative (ADNI), Dec 1 2017, In : Neurobiology of Aging. 60, p. 92-103 12 p.

Research output: Contribution to journalArticle

Neurogenesis
Alzheimer Disease
Genes
Social Adjustment
Parahippocampal Gyrus
27 Citations (Scopus)

Tau, amyloid, and cascading network failure across the Alzheimer's disease spectrum

Jones, D. T., Graff-Radford, J., Lowe, V., Wiste, H. J., Gunter, J. L., Senjem, M. L., Botha, H., Kantarci, K. M., Boeve, B. F., Knopman, D. S., Petersen, R. C. & Jack, C. R. J., 2017, (Accepted/In press) In : Cortex.

Research output: Contribution to journalArticle

Amyloid
Alzheimer Disease
Brain
Phenotype
Molecular Imaging
44 Citations (Scopus)
Tauopathies
Neurofibrillary Tangles
Amyloid
Cognition
Atrophy
29 Citations (Scopus)
Amyloid
Positron-Emission Tomography
Alzheimer Disease
Neurofibrillary Tangles
Brain
136 Citations (Scopus)

TIA1 Mutations in Amyotrophic Lateral Sclerosis and Frontotemporal Dementia Promote Phase Separation and Alter Stress Granule Dynamics

Mackenzie, I. R., Nicholson, A. M., Sarkar, M., Messing, J., Purice, M. D., Pottier, C., Annu, K., Baker, M., Perkerson, R. B., Kurti, A., Matchett, B. J., Mittag, T., Temirov, J., Hsiung, G. Y. R., Krieger, C., Murray, M. E., Kato, M., Fryer, J. D., Petrucelli, L., Zinman, L. & 22 others, Weintraub, S., Mesulam, M., Keith, J., Zivkovic, S. A., Hirsch-Reinshagen, V., Roos, R. P., Züchner, S., Graff Radford, N. R., Petersen, R. C., Caselli, R. J., Wszolek, Z. K., Finger, E., Lippa, C., Lacomis, D., Stewart, H., Dickson, D. W., Kim, H. J., Rogaeva, E., Bigio, E., Boylan, K. B., Taylor, J. P. & Rademakers, R. V., Aug 16 2017, In : Neuron. 95, 4, p. 808-816.e9

Research output: Contribution to journalArticle

Mutation
DNA-Binding Proteins
Hyalin
Phase Transition
Amyotrophic Lateral Sclerosis
33 Citations (Scopus)

Transethnic genome-wide scan identifies novel Alzheimer's disease loci

Jun, G. R., Chung, J., Mez, J., Barber, R., Beecham, G. W., Bennett, D. A., Buxbaum, J. D., Byrd, G. S., Carrasquillo, M. M., Crane, P. K., Cruchaga, C., De Jager, P., Ertekin-Taner, N., Evans, D., Fallin, M. D., Foroud, T. M., Friedland, R. P., Goate, A. M., Carrasquillo, M. M., Taner, N. & 31 others, Graff Radford, N. R., Younkin, S. G., Inzelberg, R., Kamboh, M. I., Kauwe, J. S. K., Kukull, W. A., Kunkle, B. W., Kuwano, R., Larson, E. B., Logue, M. W., Manly, J. J., Martin, E. R., Montine, T. J., Mukherjee, S., Naj, A., Reiman, E. M., Reitz, C., Sherva, R., St. George-Hyslop, P. H., Thornton, T., Younkin, S. G., Vardarajan, B. N., Wang, L. S., Wendlund, J. R., Winslow, A. R., Haines, J., Mayeux, R., Pericak-Vance, M. A., Schellenberg, G., Lunetta, K. L. & Petersen, R. C., 2017, (Accepted/In press) In : Alzheimer's and Dementia.

Research output: Contribution to journalArticle

Alzheimer Disease
Genome
Single Nucleotide Polymorphism
Genome-Wide Association Study
Genetic Loci
3 Citations (Scopus)

Uptake of AV-1451 in meningiomas

Bruinsma, T. J., Johnson, D. R., Fang, P., Senjem, M., Josephs, K. A., Whitwell, J. L., Boeve, B. F., Pandey, M., Kantarci, K. M., Jones, D. T., Vemuri, P. D., Murray, M. E., Graff-Radford, J., Schwarz, C., Knopman, D. S., Petersen, R. C., Jack, C. R. J. & Lowe, V., Sep 8 2017, (Accepted/In press) In : Annals of Nuclear Medicine. p. 1-8 8 p.

Research output: Contribution to journalArticle

Meningioma
Neoplasms
Students
Fluorine
Alzheimer Disease
8 Citations (Scopus)

Weighting and standardization of frequencies to determine prevalence of AD imaging biomarkers

Roberts, R. O., Knopman, D. S., Syrjanen, J. A., Aakre, J. A., Vassilaki, M., Kremers, W. K., Mielke, M. M., Machulda, M. M., Graff-Radford, J., Geda, Y. E., Vemuri, P. D., Lowe, V., Jack, C. R. J. & Petersen, R. C., Nov 14 2017, In : Neurology. 89, 20, p. 2039-2048 10 p.

Research output: Contribution to journalArticle

Alzheimer Disease
Biomarkers
Amyloid
Population
Brain
34 Citations (Scopus)

White-matter integrity on DTI and the pathologic staging of Alzheimer's disease

Kantarci, K. M., Murray, M. E., Schwarz, C., Reid, R. I., Przybelski, S. A., Lesnick, T., Zuk, S. M., Raman, M. R., Senjem, M. L., Gunter, J. L., Boeve, B. F., Knopman, D. S., Parisi, J. E., Petersen, R. C., Jack, C. R. J. & Dickson, D. W., Aug 1 2017, In : Neurobiology of Aging. 56, p. 172-179 8 p.

Research output: Contribution to journalArticle

Neurofibrillary Tangles
Diffusion Magnetic Resonance Imaging
Alzheimer Disease
Parietal Lobe
Anisotropy
2 Citations (Scopus)

Zeroing out preventable disability: Daring to dream the impossible dream for dementia care: Recommendations for a national plan to advance dementia care and maximize functioning

Khachaturian, A. S., Hoffman, D. P., Frank, L., Petersen, R. C., Carson, B. R. & Khachaturian, Z. S., Oct 1 2017, In : Alzheimer's and Dementia. 13, 10, p. 1077-1080 4 p.

Research output: Contribution to journalEditorial

Dementia
2016
60 Citations (Scopus)

[18F]AV-1451 tau positron emission tomography in progressive supranuclear palsy

Whitwell, J. L., Lowe, V., Tosakulwong, N., Weigand, S. D., Senjem, M. L., Schwarz, C., Spychalla, A. J., Petersen, R. C., Jack, C. R. J. & Josephs, K. A., 2016, (Accepted/In press) In : Movement Disorders.

Research output: Contribution to journalArticle

Progressive Supranuclear Palsy
Positron-Emission Tomography
Alzheimer Disease
Globus Pallidus
Tauopathies
264 Citations (Scopus)

A/T/N: An unbiased descriptive classification scheme for Alzheimer disease biomarkers

Jack, C. R. J., Bennett, D. A., Blennow, K., Carrillo, M. C., Feldman, H. H., Frisoni, G. B., Hampel, H., Jagust, W. J., Johnson, K. A., Knopman, D. S., Petersen, R. C., Scheltens, P., Sperling, R. A. & Dubois, B., Aug 2 2016, In : Neurology. 87, 5, p. 539-547 9 p.

Research output: Contribution to journalReview article

Alzheimer Disease
Biomarkers
Amyloid
Fluorodeoxyglucose F18
Research
10 Citations (Scopus)

ABCA7 loss-of-function variants, expression, and neurologic disease risk

Allen, M., Lincoln, S. J., Corda, M., Watzlawik, J. O., Carrasquillo, M. M., Reddy, J. S., Burgess, J. D., Nguyen, T., Malphrus, K., Petersen, R. C., Graff Radford, N. R., Dickson, D. W. & Taner, N., Jan 1 2016, In : Neurology: Genetics. 3, 1, e126.

Research output: Contribution to journalArticle

Nervous System Diseases
Adenosine Triphosphate
Alzheimer Disease
Messenger RNA
Proteins
19 Citations (Scopus)

A candidate regulatory variant at the TREM gene cluster associates with decreased Alzheimer's disease risk and increased TREML1 and TREM2 brain gene expression

Carrasquillo, M. M., Allen, M., Burgess, J. D., Wang, X., Strickland, S. L., Aryal, S., Siuda, J., Kachadoorian, M. L., Medway, C., Younkin, C. S., Nair, A., Wang, C., Chanana, P., Serie, D., Nguyen, T., Lincoln, S., Malphrus, K. G., Morgan, K., Golde, T. E., Price, N. D. & 10 others, White, C. C., De Jager, P. L., Bennett, D. A., Asmann, Y., Crook, J., Petersen, R. C., Graff Radford, N. R., Dickson, D. W., Younkin, S. G. & Taner, N., 2016, (Accepted/In press) In : Alzheimer's and Dementia.

Research output: Contribution to journalArticle

Multigene Family
Alzheimer Disease
Quantitative Trait Loci
Gene Expression
Meta-Analysis
14 Citations (Scopus)

Age and neurodegeneration imaging biomarkers in persons with Alzheimer disease dementia

Knopman, D. S., Jack, C. R. J., Wiste, H. J., Weigand, S. D., Vemuri, P. D., Lowe, V., Kantarci, K. M., Gunter, J. L., Senjem, M. L., Mielke, M. M., Machulda, M. M., Roberts, R. O., Boeve, B. F., Jones, D. T. & Petersen, R. C., Aug 16 2016, In : Neurology. 87, 7, p. 691-698 8 p.

Research output: Contribution to journalArticle

Alzheimer Disease
Biomarkers
Fluorodeoxyglucose F18
Amyloid
Research Design
50 Citations (Scopus)

A large-scale comparison of cortical thickness and volume methods for measuring Alzheimer's disease severity

Schwarz, C., Gunter, J. L., Wiste, H. J., Przybelski, S. A., Weigand, S. D., Ward, C. P., Senjem, M. L., Vemuri, P. D., Murray, M. E., Dickson, D. W., Parisi, J. E., Kantarci, K. M., Weiner, M. W., Petersen, R. C. & Jack, C. R. J., 2016, In : NeuroImage: Clinical. 11, p. 802-812 11 p.

Research output: Contribution to journalArticle

Alzheimer Disease
Neurofibrillary Tangles
Head
Autopsy
Parietal Lobe
30 Citations (Scopus)

Alzheimer's disease risk polymorphisms regulate gene expression in the ZCWPW1 and the CELF1 loci

Alzheimer's Disease Genetics Consortium (ADGC), Feb 1 2016, In : PLoS One. 11, 2, e0148717.

Research output: Contribution to journalArticle

Genome-Wide Association Study
Alzheimer disease
Polymorphism
Gene expression
Alzheimer Disease
26 Citations (Scopus)

Amyloid-β deposition and regional grey matter atrophy rates in dementia with Lewy bodies

Sarro, L., Senjem, M. L., Lundt, E. S., Przybelski, S. A., Lesnick, T. G., Graff-Radford, J., Boeve, B. F., Lowe, V., Ferman, T. J., Knopman, D. S., Comi, G., Filippi, M., Petersen, R. C., Jack, C. R. J. & Kantarci, K. M., Oct 1 2016, In : Brain. 139, 10, p. 2740-2750 11 p.

Research output: Contribution to journalArticle

Lewy Body Disease
Amyloid
Atrophy
Magnetic Resonance Imaging
Positron-Emission Tomography
167 Citations (Scopus)
DNA-Binding Proteins
Tauopathies
Neurofibrillary Tangles
Dementia
Alzheimer Disease
9 Citations (Scopus)

An investigation of cerebrovascular lesions in dementia with Lewy bodies compared to Alzheimer's disease

Sarro, L., Tosakulwong, N., Schwarz, C., Graff-Radford, J., Przybelski, S. A., Lesnick, T. G., Zuk, S. M., Reid, R. I., Raman, M. R., Boeve, B. F., Ferman, T. J., Knopman, D. S., Comi, G., Filippi, M., Murray, M. E., Parisi, J. E., Dickson, D. W., Petersen, R. C., Jack, C. R. J. & Kantarci, K. M., 2016, (Accepted/In press) In : Alzheimer's and Dementia.

Research output: Contribution to journalArticle

Lewy Body Disease
Alzheimer Disease
Vascular Diseases
Cardiovascular Diseases
White Matter
78 Citations (Scopus)

A novel Alzheimer disease locus located near the gene encoding tau protein

Jun, G., Ibrahim-Verbaas, C. A., Vronskaya, M., Lambert, J. C., Chung, J., Naj, A. C., Kunkle, B. W., Wang, L. S., Bis, J. C., Bellenguez, C., Harold, D., Lunetta, K. L., Destefano, A. L., Grenier-Boley, B., Sims, R., Beecham, G. W., Smith, A. V., Chouraki, V., Hamilton-Nelson, K. L., Ikram, M. A. & 97 others, Fievet, N., Denning, N., Martin, E. R., Schmidt, H., Kamatani, Y., Dunstan, M. L., Valladares, O., Laza, A. R., Zelenika, D., Ramirez, A., Foroud, T. M., Choi, S. H., Boland, A., Becker, T., Kukull, W. A., Van Der Lee, S. J., Pasquier, F., Cruchaga, C., Beekly, D., Fitzpatrick, A. L., Hanon, O., Gill, M., Barber, R., Gudnason, V., Campion, D., Love, S., Bennett, D. A., Amin, N., Berr, C., Tsolaki, M., Buxbaum, J. D., Lopez, O. L., Deramecourt, V., Fox, N. C., Cantwell, L. B., Tárraga, L., Dufouil, C., Hardy, J., Crane, P. K., Eiriksdottir, G., Hannequin, D., Clarke, R., Evans, D., Mosley, T. H., Letenneur, L., Brayne, C., Maier, W., De Jager, P., Emilsson, V., Dartigues, J. F., Hampel, H., Kamboh, M. I., De Bruijn, R. F. A. G., Tzourio, C., Pastor, P., Larson, E. B., Rotter, J. I., O'Donovan, M. C., Montine, T. J., Nalls, M. A., Mead, S., Reiman, E. M., Jonsson, P. V., Holmes, C., St George-Hyslop, P. H., Boada, M., Passmore, P., Wendland, J. R., Schmidt, R., Morgan, K., Winslow, A. R., Powell, J. F., Carrasquillo, M. M., Younkin, S. G., Jakobsdóttir, J., Kauwe, J. S. K., Wilhelmsen, K. C., Rujescu, D., Nöthen, M. M., Hofman, A., Jones, L., Haines, J. L., Psaty, B. M., Van Broeckhoven, C., Holmans, P., Launer, L. J., Mayeux, R., Lathrop, M., Goate, A. M., Escott-Price, V., Seshadri, S., Pericak-Vance, M. A., Amouyel, P., Williams, J., Van Duijn, C. M., Schellenberg, G. D. & Petersen, R. C., Jan 1 2016, In : Molecular Psychiatry. 21, 1, p. 108-117 10 p.

Research output: Contribution to journalArticle

tau Proteins
Single Nucleotide Polymorphism
Alzheimer Disease
Genes
Exons
19 Citations (Scopus)

Assessment of the genetic variance of late-onset Alzheimer's disease

Alzheimer's Disease Genetics Consortium (ADGC), May 1 2016, In : Neurobiology of Aging. 41, p. 200.e13-200.e20

Research output: Contribution to journalArticle

Alzheimer Disease
Single Nucleotide Polymorphism
Inborn Genetic Diseases
Amyloid beta-Protein Precursor
Myeloid Cells
81 Citations (Scopus)

Association between anticholinergic medication use and cognition, brain metabolism, and brain atrophy in cognitively normal older adults

Alzheimer's Disease Neuroimaging Initiative, Jun 1 2016, In : JAMA Neurology. 73, 6, p. 721-732 12 p.

Research output: Contribution to journalArticle

Cholinergic Antagonists
Cognition
Atrophy
Brain
Neuroimaging
92 Citations (Scopus)

Association between olfactory dysfunction and amnestic mild cognitive impairment and Alzheimer disease dementia

Roberts, R. O., Christianson, T. J. H., Kremers, W. K., Mielke, M. M., Machulda, M. M., Vassilaki, M., Alhurani, R. E., Geda, Y. E., Knopman, D. S. & Petersen, R. C., Jan 1 2016, In : JAMA Neurology. 73, 1, p. 93-101 9 p.

Research output: Contribution to journalArticle

Alzheimer Disease
Smell
Cognitive Dysfunction
Lost to Follow-Up
Cognition
71 Citations (Scopus)

Association of elevated amyloid levels with cognition and biomarkers in cognitively normal people from the community

Petersen, R. C., Wiste, H. J., Weigand, S. D., Rocca, W. A., Roberts, R. O., Mielke, M. M., Lowe, V., Knopman, D. S., Pankratz, V. S., Machulda, M. M., Geda, Y. E. & Jack, C. R. J., Jan 1 2016, In : JAMA Neurology. 73, 1, p. 85-92 8 p.

Research output: Contribution to journalArticle

Amyloid
Cognition
Biomarkers
Positron-Emission Tomography
Alzheimer Disease
28 Citations (Scopus)

Association of Mild Cognitive Impairment With Exposure to General Anesthesia for Surgical and Nonsurgical Procedures: A Population-Based Study

Sprung, J., Roberts, R. O., Knopman, D. S., Olive, D. M., Gappa, J. L., Sifuentes, V. L., Behrend, T. L., Farmer, J. D., Weingarten, T. N., Hanson, A. C., Schroeder, D. R., Petersen, R. C. & Warner, D. O., Feb 1 2016, In : Mayo Clinic Proceedings. 91, 2, p. 208-217 10 p.

Research output: Contribution to journalArticle

General Anesthesia
Population
Anesthesia
Cognitive Dysfunction
Nervous System
56 Citations (Scopus)

AV-1451 tau and β-amyloid positron emission tomography imaging in dementia with Lewy bodies

Kantarci, K. M., Lowe, V., Boeve, B. F., Senjem, M. L., Tosakulwong, N., Lesnick, T. G., Spychalla, A. J., Gunter, J. L., Fields, J. A., Graff-Radford, J., Ferman, T. J., Jones, D. T., Murray, M. E., Knopman, D. S., Jack, C. R. J. & Petersen, R. C., 2016, (Accepted/In press) In : Annals of Neurology.

Research output: Contribution to journalArticle

Lewy Body Disease
Amyloid
Positron-Emission Tomography
Alzheimer Disease
Occipital Lobe
67 Citations (Scopus)

CCNF mutations in amyotrophic lateral sclerosis and frontotemporal dementia

Williams, K. L., Topp, S., Yang, S., Smith, B., Fifita, J. A., Warraich, S. T., Zhang, K. Y., Farrawell, N., Vance, C., Hu, X., Chesi, A., Leblond, C. S., Lee, A., Rayner, S. L., Sundaramoorthy, V., Dobson-Stone, C., Molloy, M. P., Van Blitterswijk, M., Dickson, D. W., Petersen, R. C. & 48 others, Graff Radford, N. R., Boeve, B. F., Murray, M. E., Pottier, C., Don, E., Winnick, C., McCann, E. P., Hogan, A., Daoud, H., Levert, A., Dion, P. A., Mitsui, J., Ishiura, H., Takahashi, Y., Goto, J., Kost, J., Gellera, C., Gkazi, A. S., Miller, J., Stockton, J., Brooks, W. S., Boundy, K., Polak, M., Muñoz-Blanco, J. L., Esteban-Pérez, J., Rábano, A., Hardiman, O., Morrison, K. E., Ticozzi, N., Silani, V., De Belleroche, J., Glass, J. D., Kwok, J. B. J., Guillemin, G. J., Chung, R. S., Tsuji, S., Brown, R. H., García-Redondo, A., Rademakers, R. V., Landers, J. E., Gitler, A. D., Rouleau, G. A., Cole, N. J., Yerbury, J. J., Atkin, J. D., Shaw, C. E., Nicholson, G. A. & Blair, I. P., Apr 15 2016, In : Nature Communications. 7, 11253.

Research output: Contribution to journalArticle

Ubiquitinated Proteins
mutations
Ubiquitin-Protein Ligase Complexes
proteins
Mutation
17 Citations (Scopus)

Cerebral Amyloid Deposition Is Associated with Gait Parameters in the Mayo Clinic Study of Aging

Wennberg, A. M. V., Savica, R., Hagen, C. E., Roberts, R. O., Knopman, D. S., Hollman, J. H., Vemuri, P. D., Jack, C. R. J., Petersen, R. C. & Mielke, M. M., 2016, (Accepted/In press) In : Journal of the American Geriatrics Society.

Research output: Contribution to journalArticle

Gait
Amyloid
Gyrus Cinguli
Linear Models
Normal Pressure Hydrocephalus
14 Citations (Scopus)

Characterizing white matter tract degeneration in syndromic variants of Alzheimer's disease: A diffusion tensor imaging study

Madhavan, A., Schwarz, C., Duffy, J. R., Strand, E. A., Machulda, M. M., Drubach, D., Kantarci, K. M., Przybelski, S. A., Reid, R. I., Senjem, M. L., Gunter, J. L., Apostolova, L. G., Lowe, V., Petersen, R. C., Jack, C. R. J., Josephs, K. A. & Whitwell, J. L., 2016, In : Journal of Alzheimer's Disease. 49, 3, p. 633-643 11 p.

Research output: Contribution to journalArticle

Diffusion Tensor Imaging
Alzheimer Disease
Atrophy
Corpus Callosum
Primary Progressive Aphasia
34 Citations (Scopus)

Chronic depressive symptomatology in mild cognitive impairment is associated with frontal atrophy rate which hastens conversion to Alzheimer dementia

Sacuiu, S., Insel, P. S., Mueller, S., Tosun, D., Mattsson, N., Jack, C. R. J., DeCarli, C., Petersen, R. C., Aisen, P. S., Weiner, M. W. & Scott MacKin, R., Feb 1 2016, In : American Journal of Geriatric Psychiatry. 24, 2, p. 126-135 10 p.

Research output: Contribution to journalArticle

Atrophy
Alzheimer Disease
Depression
Cognitive Dysfunction
Gyrus Cinguli

Corrigendum to “Genome-wide association interaction analysis for Alzheimer's disease.” [Neurobiol. Aging (2014) 35 (2436–2443)] (S0197458014003777)(10.1016/j.neurobiolaging.2014.05.014)

Gusareva, E. S., Carrasquillo, M. M., Bellenguez, C., Cuyvers, E., Colon, S., Graff Radford, N. R., Petersen, R. C., Dickson, D. W., Mahachie John, J. M., Bessonov, K., Van Broeckhoven, C., Ramirez, A., Harold, D., Williams, J., Amouyel, P., Sleegers, K., Taner, N., Lambert, J. C. & Van Steen, K., Jan 1 2016, In : Neurobiology of Aging. 37, p. 211 1 p.

Research output: Contribution to journalComment/debate

Genome-Wide Association Study
Germany
Psychiatry
Alzheimer Disease
corrigendum
24 Citations (Scopus)

Decline in weight and incident mild cognitive impairment Mayo Clinic study of aging

Alhurani, R. E., Vassilaki, M., Aakre, J. A., Mielke, M. M., Kremers, W. K., Machulda, M. M., Geda, Y. E., Knopman, D. S., Petersen, R. C. & Roberts, R. O., Apr 1 2016, In : JAMA Neurology. 73, 4, p. 439-446 8 p.

Research output: Contribution to journalArticle

Weights and Measures
Dementia
Body Mass Index
Medical Record Linkage
Prodromal Symptoms
108 Citations (Scopus)

Defining imaging biomarker cut points for brain aging and Alzheimer's disease

Jack, C. R. J., Wiste, H. J., Weigand, S. D., Therneau, T. M., Lowe, V., Knopman, D. S., Gunter, J. L., Senjem, M. L., Jones, D. T., Kantarci, K. M., Machulda, M. M., Mielke, M. M., Roberts, R. O., Vemuri, P. D., Reyes, D. A. & Petersen, R. C., 2016, (Accepted/In press) In : Alzheimer's and Dementia.

Research output: Contribution to journalArticle

Brain Diseases
Positron-Emission Tomography
Alzheimer Disease
Biomarkers
Deoxyglucose
217 Citations (Scopus)

Early role of vascular dysregulation on late-onset Alzheimer's disease based on multifactorial data-driven analysis

The Alzheimer's Disease Neuroimaging Initiative, Jun 21 2016, In : Nature Communications. 7, 11934.

Research output: Contribution to journalArticle

Blood Vessels
Alzheimer Disease
Biomarkers
biomarkers
Disease Progression
37 Citations (Scopus)

Effect of intellectual enrichment on AD biomarker trajectories

Vemuri, P. D., Lesnick, T. G., Przybelski, S. A., Knopman, D. S., Machulda, M. M., Lowe, V., Mielke, M. M., Roberts, R. O., Gunter, J. L., Senjem, M. L., Geda, Y. E., Rocca, W. A., Petersen, R. C. & Jack, C. R. J., Mar 22 2016, In : Neurology. 86, 12, p. 1128-1135 8 p.

Research output: Contribution to journalArticle

Dementia
Alzheimer Disease
Biomarkers
Exercise
Occupations
7 Citations (Scopus)

Evolution of neurodegeneration-imaging biomarkers from clinically normal to dementia in the Alzheimer disease spectrum

Knopman, D. S., Jack, C. R. J., Lundt, E. S., Weigand, S. D., Vemuri, P. D., Lowe, V., Kantarci, K. M., Gunter, J. L., Senjem, M. L., Mielke, M. M., Machulda, M. M., Roberts, R. O., Boeve, B. F., Jones, D. T. & Petersen, R. C., Oct 1 2016, In : Neurobiology of Aging. 46, p. 32-42 11 p.

Research output: Contribution to journalArticle

Dementia
Alzheimer Disease
Biomarkers
Positron-Emission Tomography
Parietal Lobe
19 Citations (Scopus)
Fatigue
Brain
Linear Models
Temporal Lobe
Atrophy
14 Citations (Scopus)

FDG-PET and Neuropsychiatric Symptoms among Cognitively Normal Elderly Persons: The Mayo Clinic Study of Aging

Krell-Roesch, J., Ruider, H., Lowe, V., Stokin, G. B., Pink, A., Roberts, R. O., Mielke, M. M., Knopman, D. S., Christianson, T. J., Machulda, M. M., Jack, C. R. J., Petersen, R. C. & Geda, Y. E., 2016, In : Journal of Alzheimer's Disease. 53, 4, p. 1609-1616 8 p.

Research output: Contribution to journalArticle

Asymptomatic Diseases
Equipment and Supplies
Alzheimer Disease
Odds Ratio
Depression
8 Citations (Scopus)

First PET imaging studies with 63Zn-zinc citrate in healthy human participants and patients with Alzheimer disease

DeGrado, T. R., Kemp, B. J., Pandey, M., Jiang, H., Gunderson, T. M., Linscheid, L. R., Woodwick, A. R., McConnell, D. M., Fletcher, J. G., Johnson, G. B., Petersen, R. C., Knopman, D. S. & Lowe, V., 2016, In : Molecular Imaging. 15, p. 1-10 10 p.

Research output: Contribution to journalArticle

Positron emission tomography
citrates
Citric Acid
Positron-Emission Tomography
Zinc
18 Citations (Scopus)

Frailty and Mortality Outcomes in Cognitively Normal Older People: Sex Differences in a Population-Based Study

Bartley, M. M., Geda, Y. E., Christianson, T. J. H., Shane Pankratz, V., Roberts, R. O. & Petersen, R. C., Jan 1 2016, In : Journal of the American Geriatrics Society. 64, 1, p. 132-137 6 p.

Research output: Contribution to journalArticle

Sex Characteristics
Mortality
Confidence Intervals
Population
Proportional Hazards Models
4 Citations (Scopus)

FTDP-17 with Pick body-like inclusions associated with a novel tau mutation, p.E372G

Tacik, P., Deture, M., Carlomagno, Y., Lin, W. L., Murray, M. E., Baker, M. C., Josephs, K. A., Boeve, B. F., Wszolek, Z. K., Graff Radford, N. R., Parisi, J. E., Petrucelli, L., Rademakers, R. V., Isaacson, R. S., Heilman, K. M., Petersen, R. C., Dickson, D. W. & Kouri, N., 2016, (Accepted/In press) In : Brain Pathology.

Research output: Contribution to journalArticle

Frontotemporal Dementia
Inclusion Bodies
Mutation
Microtubule-Associated Proteins
Exons
26 Citations (Scopus)

Genetic risk factors for the posterior cortical atrophy variant of Alzheimer's disease

Schott, J. M., Crutch, S. J., Carrasquillo, M. M., Uphill, J., Shakespeare, T. J., Ryan, N. S., Yong, K. X., Lehmann, M., Taner, N., Graff Radford, N. R., Boeve, B. F., Murray, M. E., Khan, Q. U. A., Petersen, R. C., Dickson, D. W., Knopman, D. S., Rabinovici, G. D., Miller, B. L., González, A. S., Gil-Néciga, E. & 24 others, Snowden, J. S., Harris, J., Pickering-Brown, S. M., Louwersheimer, E., van der Flier, W. M., Scheltens, P., Pijnenburg, Y. A., Galasko, D., Sarazin, M., Dubois, B., Magnin, E., Galimberti, D., Scarpini, E., Cappa, S. F., Hodges, J. R., Halliday, G. M., Bartley, L., Carrillo, M. C., Bras, J. T., Hardy, J., Rossor, M. N., Collinge, J., Fox, N. C. & Mead, S., Aug 1 2016, In : Alzheimer's and Dementia. 12, 8, p. 862-871 10 p.

Research output: Contribution to journalArticle

Atrophy
Alzheimer Disease
Odds Ratio
Genome-Wide Association Study
1 Citation (Scopus)

Genome-wide association study of prolactin levels in blood plasma and cerebrospinal fluid

for the Alzheimer's Disease Neuroimaging Initiative, Jun 29 2016, In : BMC Genomics. 17, 436.

Research output: Contribution to journalArticle

Genome-Wide Association Study
Prolactin
Cerebrospinal Fluid
Immune System Phenomena
Single Nucleotide Polymorphism
14 Citations (Scopus)

Hippocampal volumes predict risk of dementia with Lewy bodies in mild cognitive impairment

Kantarci, K. M., Lesnick, T., Ferman, T. J., Przybelski, S. A., Boeve, B. F., Smith, G. E., Kremers, W. K., Knopman, D. S., Jack, C. R. J. & Petersen, R. C., Nov 29 2016, In : Neurology. 87, 22, p. 2317-2323 7 p.

Research output: Contribution to journalArticle

Lewy Body Disease
Alzheimer Disease
Atrophy
Cognitive Dysfunction
33 Citations (Scopus)

Human whole genome genotype and transcriptome data for Alzheimer's and other neurodegenerative diseases

Allen, M., Carrasquillo, M. M., Funk, C., Heavner, B. D., Zou, F., Younkin, C. S., Burgess, J. D., Chai, H. S., Crook, J., Eddy, J. A., Li, H., Logsdon, B., Peters, M. A., Dang, K. K., Wang, X., Serie, D., Wang, C., Nguyen, T., Lincoln, S., Malphrus, K. & 11 others, Bisceglio, G., Li, M., Golde, T. E., Mangravite, L. M., Asmann, Y., Price, N. D., Petersen, R. C., Graff Radford, N. R., Dickson, D. W., Younkin, S. G. & Taner, N., Oct 11 2016, In : Scientific data. 3, 160089.

Research output: Contribution to journalArticle

Neurodegenerative diseases
Genotype
Brain
Genome
Genes
22 Citations (Scopus)

Impact of sex and APOE4 on cerebral amyloid angiopathy in Alzheimer’s disease

Shinohara, M., Murray, M. E., Frank, R. D., Shinohara, M., Deture, M., Yamazaki, Y., Tachibana, M., Atagi, Y., Davis, M. D., Liu, C-C., Zhao, N., Painter, M. M., Petersen, R. C., Fryer, J. D., Crook, J., Dickson, D. W., Bu, G. D. & Kanekiyo, T., May 14 2016, (Accepted/In press) In : Acta Neuropathologica. p. 1-10 10 p.

Research output: Contribution to journalArticle

Cerebral Amyloid Angiopathy
Alzheimer Disease
Apolipoproteins E
Temporal Lobe
Amyloid
8 Citations (Scopus)

Integration of bioinformatics and imaging informatics for identifying rare PSEN1 variants in Alzheimer's disease

Nho, K., Horgusluoglu, E., Kim, S., Risacher, S. L., Kim, D., Foroud, T., Aisen, P. S., Petersen, R. C., Jack, C. R. J., Shaw, L. M., Trojanowski, J. Q., Weiner, M. W., Green, R. C., Toga, A. W. & Saykin, A. J., Aug 12 2016, In : BMC Medical Genomics. 9, 30.

Research output: Contribution to journalArticle

Informatics
Computational Biology
Endophenotypes
Cerebrospinal Fluid
Alzheimer Disease
31 Citations (Scopus)

Levels of tau protein in plasma are associated with neurodegeneration and cognitive function in a population-based elderly cohort

Dage, J. L., Wennberg, A. M. V., Airey, D. C., Hagen, C. E., Knopman, D. S., Machulda, M. M., Roberts, R. O., Jack, C. R. J., Petersen, R. C. & Mielke, M. M., Dec 1 2016, In : Alzheimer's and Dementia. 12, 12, p. 1226-1234 9 p.

Research output: Contribution to journalArticle

tau Proteins
Cognition
Population
Positron-Emission Tomography
Alzheimer Disease
8 Citations (Scopus)

Longitudinal decline in mild-to-moderate Alzheimer's disease: Analyses of placebo data from clinical trials

Thomas, R. G., Albert, M., Petersen, R. C. & Aisen, P. S., 2016, (Accepted/In press) In : Alzheimer's and Dementia.

Research output: Contribution to journalArticle

Alzheimer Disease
Placebos
Clinical Trials
Population Characteristics
Dementia