Ronald Carl Petersen, MD &ndash; Research Output

2013

The role of apolipoprotein E (APOE) genotype in early mild cognitive impairment (E-MCI)

Risacher, S. L., Kim, S., Shen, L., Nho, K., Foroud, T., Green, R. C., Petersen, R. C., Jack, C. R. J., Aisen, P. S., Koeppe, R. A., Jagust, W. J., Shaw, L. M., Trojanowski, J. Q., Weiner, M. W. & Saykin, A. J., 2013, In : Frontiers in Aging Neuroscience. 5, APR, Article 11.

Research output: Contribution to journal › Article

Apolipoproteins E

Cerebrospinal Fluid

Genotype

Apolipoprotein E4

Amyloid

1579 Citations (Scopus)

Tracking pathophysiological processes in Alzheimer's disease: An updated hypothetical model of dynamic biomarkers

Jack, C. R. J., Knopman, D. S., Jagust, W. J., Petersen, R. C., Weiner, M. W., Aisen, P. S., Shaw, L. M., Vemuri, P. D., Wiste, H. J., Weigand, S. D., Lesnick, T. G., Pankratz, V. S., Donohue, M. C. & Trojanowski, J. Q., Feb 2013, In : The Lancet Neurology. 12, 2, p. 207-216 10 p.

Research output: Contribution to journal › Article

Alzheimer Disease

Biomarkers

Tauopathies

Amyloid

Brain Stem

188 Citations (Scopus)

TREM2 in neurodegeneration: Evidence for association of the p.R47H variant with frontotemporal dementia and Parkinson's disease

Rayaprolu, S., Mullen, B., Baker, M., Lynch, T., Finger, E., Seeley, W. W., Hatanpaa, K. J., Lomen-Hoerth, C., Kertesz, A., Bigio, E. H., Lippa, C., Josephs, K. A., Knopman, D. S., White, C. L., Caselli, R. J., Mackenzie, I. R., Miller, B. L., Boczarska-Jedynak, M., Opala, G., Krygowska-Wajs, A. & 13 others, Barcikowska, M., Younkin, S. G., Petersen, R. C., Taner, N., Uitti, R. J., Meschia, J. F., Boylan, K. B., Boeve, B. F., Graff Radford, N. R., Wszolek, Z. K., Dickson, D. W., Rademakers, R. V. & Ross, O. A., 2013, In : Molecular Neurodegeneration. 8, 1, 19.

Research output: Contribution to journal › Article

Frontotemporal Dementia

Myeloid Cells

Parkinson Disease

Progressive Supranuclear Palsy

Alzheimer Disease

59 Citations (Scopus)

Validation of the Mayo Sleep Questionnaire to screen for REM sleep behavior disorder in a community-based sample

Boeve, B. F., Molano, J. R., Ferman, T. J., Lin, S. C., Bieniek, K., Tippmann-Peikert, M., Boot, B., St Louis, E. K., Knopman, D. S., Petersen, R. C. & Silber, M. H., May 15 2013, In : Journal of Clinical Sleep Medicine. 9, 5, p. 475-480 6 p.

Research output: Contribution to journal › Article

REM Sleep Behavior Disorder

Sleep

Polysomnography

REM Sleep

Parasomnias

11 Citations (Scopus)

Ventricular enlargement and its clinical correlates in the imaging cohort from the adcs mci donepezil/vitamin e study

Apostolova, L. G., Babakchanian, S., Hwang, K. S., Green, A. E., Zlatev, D., Chou, Y. Y., Decarli, C., Jack, C. R. J., Petersen, R. C., Aisen, P. S., Cummings, J. L., Toga, A. W. & Thompson, P. M., Apr 2013, In : Alzheimer Disease and Associated Disorders. 27, 2, p. 174-181 8 p.

Research output: Contribution to journal › Article

Vitamins

Alzheimer Disease

Temporal Lobe

Activities of Daily Living

Lateral Ventricles

48 Citations (Scopus)

Whole-exome sequencing and imaging genetics identify functional variants for rate of change in hippocampal volume in mild cognitive impairment

Nho, K., Corneveaux, J. J., Kim, S., Lin, H., Risacher, S. L., Shen, L., Swaminathan, S., Ramanan, V. K., Liu, Y., Foroud, T., Inlow, M. H., Siniard, A. L., Reiman, R. A., Aisen, P. S., Petersen, R. C., Green, R. C., Jack, C. R. J., Weiner, M. W., Baldwin, C. T., Lunetta, K. & 14 others, Farrer, L. A., Furney, S. J., Lovestone, S., Simmons, A., Mecocci, P., Vellas, B., Tsolaki, M., Kloszewska, I., Soininen, H., McDonald, B. C., Farlow, M. R., Ghetti, B., Huentelman, M. J. & Saykin, A. J., Jul 2013, In : Molecular Psychiatry. 18, 7, p. 781-787 7 p.

Research output: Contribution to journal › Article

Apolipoprotein E3

Exome

Atrophy

Neuroimaging

Alzheimer Disease

2012

1 Citation (Scopus)

Adapting a PET Imaging Agent for Correlative Microscopy of Meningiomas and Other Intracranial Tumors

Lingle, W. L., Negron, V., Johnson, G. B., Nathan, M. A., Parasi, J. E., Johnson, A. J., Hunt, C. H., Peller, P. J., Broski, S., Fauq, A. H., Jack, C. R. J., Petersen, R. C., Klunk, W. E., Mathis, C. A. & Lowe, V., 2012, In : Microscopy and Microanalysis. 18, p. 178-179 2 p.

Research output: Contribution to journal › Article

Tumors

Microscopic examination

tumors

microscopy

Imaging techniques

35 Citations (Scopus)

Advancing Alzheimer's disease diagnosis, treatment, and care: Recommendations from the Ware Invitational Summit

Naylor, M. D., Karlawish, J. H., Arnold, S. E., Khachaturian, A. S., Khachaturian, Z. S., Lee, V. M. Y., Baumgart, M., Banerjee, S., Beck, C., Blennow, K., Brookmeyer, R., Brunden, K. R., Buckwalter, K. C., Comer, M., Covinsky, K., Feinberg, L. F., Frisoni, G., Green, C., Guimaraes, R. M., Gwyther, L. P. & 24 others, Hefti, F. F., Hutton, M., Kawas, C., Kent, D. M., Kuller, L., Langa, K. M., Mahley, R. W., Maslow, K., Masters, C. L., Meier, D. E., Neumann, P. J., Paul, S. M., Petersen, R. C., Sager, M. A., Sano, M., Schenk, D., Soares, H., Sperling, R. A., Stahl, S. M., Van Deerlin, V., Stern, Y., Weir, D., Wolk, D. A. & Trojanowski, J. Q., Sep 2012, In : Alzheimer's and Dementia. 8, 5, p. 445-452 8 p.

Research output: Contribution to journal › Article

Health Services Research

Health Policy

Ethics

Neurodegenerative Diseases

Alzheimer Disease

26 Citations (Scopus)

Alzheimer's disease therapeutic trials: Eu/us task force report on recruitment, retention, and methodology

Vellas, B., Hampel, H., Rouge-Bugat, M. E., Grundman, M., Andrieu, S., Abu-Shakra, S., Bateman, R., Berman, R., Black, R., Carrillo, M., Donohue, M., Mintun, M., Morris, J., Petersen, R. C., Thomas, R. G., Suhy, J., Schneider, L., Seely, L., Tariot, P., Touchon, J. & 3 others, Weiner, M., Sampaio, C. & Aisen, P., Apr 2012, In : Journal of Nutrition, Health and Aging. 16, 4, p. 339-345 7 p.

Research output: Contribution to journal › Article

Advisory Committees

Alzheimer Disease

Prodromal Symptoms

Spinal Puncture

Primary Care Physicians

287 Citations (Scopus)

Amyloid deposition, hypometabolism, and longitudinal cognitive decline

Landau, S. M., Mintun, M. A., Joshi, A. D., Koeppe, R. A., Petersen, R. C., Aisen, P. S., Weiner, M. W. & Jagust, W. J., Oct 2012, In : Annals of Neurology. 72, 4, p. 578-586 9 p.

Research output: Contribution to journal › Article

Amyloid

Alzheimer Disease

Neuroimaging

Positron-Emission Tomography

Cognition

376 Citations (Scopus)

An operational approach to National Institute on Aging-Alzheimer's Association criteria for preclinical Alzheimer disease

Jack, C. R. J., Knopman, D. S., Weigand, S. D., Wiste, H. J., Vemuri, P. D., Lowe, V., Kantarci, K. M., Gunter, J. L., Senjem, M. L., Ivnik, R. J., Roberts, R. O., Rocca, W. A., Boeve, B. F. & Petersen, R. C., Jun 2012, In : Annals of Neurology. 71, 6, p. 765-775 11 p.

Research output: Contribution to journal › Article

National Institute on Aging (U.S.)

Alzheimer Disease

Biomarkers

Positron-Emission Tomography

Population

50 Citations (Scopus)

Ante mortem amyloid imaging and β-amyloid pathology in a case with dementia with Lewy bodies

Kantarci, K. M., Yang, C., Schneider, J. A., Senjem, M. L., Reyes, D. A., Lowe, V., Barnes, L. L., Aggarwal, N. T., Bennett, D. A., Smith, G. E., Petersen, R. C., Jack, C. R. J. & Boeve, B. F., May 2012, In : Neurobiology of Aging. 33, 5, p. 878-885 8 p.

Research output: Contribution to journal › Article

Lewy Body Disease

Amyloid

Pathology

Positron-Emission Tomography

Lewy Bodies

2 Citations (Scopus)

ApoE and Quality of Life in Nonagenarians

Parsaik, A. K., Lapid, M. I., Rummans, T. A., Cha, R. H., Boeve, B. F., Pankratz, V. S., Tangalos, E. G. & Petersen, R. C., Oct 2012, In : Journal of the American Medical Directors Association. 13, 8, p. 704-707 4 p.

Research output: Contribution to journal › Article

Apolipoproteins E

Quality of Life

Dementia

Parkinsonian Disorders

Aptitude

114 Citations (Scopus)

APOE modifies the association between Aβ load and cognition in cognitively normal older adults

Kantarci, K. M., Lowe, V., Przybelski, S. A., Weigand, S. D., Senjem, M. L., Ivnik, R. J., Preboske, G. M., Roberts, R. O., Geda, Y. E., Boeve, B. F., Knopman, D. S., Petersen, R. C. & Jack, C. R. J., Jan 24 2012, In : Neurology. 78, 4, p. 232-240 9 p.

Research output: Contribution to journal › Article

Cognition

Linear Models

Parietal Lobe

Sex Education

Frontal Lobe

13 Citations (Scopus)

Association and heterogeneity at the GAPDH locus in Alzheimer's disease

Allen, M., Cox, C., Belbin, O., Ma, L., Bisceglio, G. D., Wilcox, S. L., Howell, C. C., Hunter, T. A., Culley, O., Walker, L. P., Carrasquillo, M. M., Dickson, D. W., Petersen, R. C., Graff Radford, N. R., Younkin, S. G. & Taner, N., Jan 2012, In : Neurobiology of Aging. 33, 1

Research output: Contribution to journal › Article

Glyceraldehyde-3-Phosphate Dehydrogenases

Alzheimer Disease

Single Nucleotide Polymorphism

Meta-Analysis

Alleles

34 Citations (Scopus)

Aβ imaging: Feasible, pertinent, and vital to progress in Alzheimer's disease

Villemagne, V. L., Klunk, W. E., Mathis, C. A., Rowe, C. C., Brooks, D. J., Hyman, B. T., Ikonomovic, M. D., Ishii, K., Jack, C. R. J., Jagust, W. J., Johnson, K. A., Koeppe, R. A., Lowe, V., Masters, C. L., Montine, T. J., Morris, J. C., Nordberg, A., Petersen, R. C., Reiman, E. M., Selkoe, D. J. & 4 others, Sperling, R. A., Van Laere, K., Weiner, M. W. & Drzezga, A., Feb 2012, In : European Journal of Nuclear Medicine and Molecular Imaging. 39, 2, p. 209-219 11 p.

Research output: Contribution to journal › Article

Amyloid beta-Peptides

Radioisotopes

Positron-Emission Tomography

Alzheimer Disease

131 Citations (Scopus)

Brain expression genome-wide association study (eGWAS) identifies human disease-associated variants

Zou, F., Chai, H. S., Younkin, C. S., Allen, M., Crook, J., Pankratz, V. S., Carrasquillo, M. M., Rowley, C. N., Nair, A. A., Middha, S., Maharjan, S., Nguyen, T., Ma, L., Malphrus, K. G., Palusak, R., Lincoln, S., Bisceglio, G., Georgescu, C., Kouri, N., Kolbert, C. P. & 11 others, Jen, J., Haines, J. L., Mayeux, R., Pericak-Vance, M. A., Farrer, L. A., Schellenberg, G. D., Petersen, R. C., Graff Radford, N. R., Dickson, D. W., Younkin, S. G. & Taner, N., Jun 2012, In : PLoS Genetics. 8, 6, e1002707.

Research output: Contribution to journal › Article

Genome-Wide Association Study

human diseases

brain

genome

Brain

17 Citations (Scopus)

Characterization of a family with c9FTD/ALS associated with the GGGGCC repeat expansion in C9ORF72

Savica, R., Adeli, A., Vemuri, P. D., Knopman, D. S., DeJesus-Hernandez, M., Rademakers, R. V., Fields, J. A., Whitwell, J. L., Jack, C. R. J., Lowe, V., Petersen, R. C. & Boeve, B. F., Sep 2012, In : Archives of Neurology. 69, 9, p. 1164-1169 6 p.

Research output: Contribution to journal › Article

Chromosomes, Human, Pair 9

Amyotrophic Lateral Sclerosis

Open Reading Frames

Neuroimaging

Parkinsonian Disorders

229 Citations (Scopus)

Characterization of frontotemporal dementia and/or amyotrophic lateral sclerosis associated with the GGGGCC repeat expansion in C9ORF72

Boeve, B. F., Boylan, K. B., Graff Radford, N. R., Dejesus-Hernandez, M., Knopman, D. S., Pedraza, O. D., Vemuri, P. D., Jones, D. T., Lowe, V., Murray, M. E., Dickson, D. W., Josephs, K. A., Rush, B. K., Machulda, M. M., Fields, J. A., Ferman, T. J., Baker, M., Rutherford, N. J., Adamson, J., Wszolek, Z. K. & 13 others, Adeli, A., Savica, R., Boot, B., Kuntz, K. M., Gavrilova, R. M., Reeves, A., Whitwell, J. L., Kantarci, K. M., Jack, C. R. J., Parisi, J. E., Lucas, J. A., Petersen, R. C. & Rademakers, R. V., Mar 2012, In : Brain. 135, 3, p. 765-783 19 p.

Research output: Contribution to journal › Article

Parkinsonian Disorders

Age of Onset

Frontotemporal Dementia

Chromosomes, Human, Pair 9

Neuroimaging

139 Citations (Scopus)

Common genetic variants in the CLDN2 and PRSS1-PRSS2 loci alter risk for alcohol-related and sporadic pancreatitis

Whitcomb, D. C., LaRusch, J., Krasinskas, A. M., Klei, L., Smith, J. P., Brand, R. E., Neoptolemos, J. P., Lerch, M. M., Tector, M., Sandhu, B. S., Guda, N. M., Orlichenko, L., Alkaade, S., Amann, S. T., Anderson, M. A., Baillie, J., Banks, P. A., Conwell, D., Coté, G. A., Cotton, P. B. & 178 others, DiSario, J., Farrer, L. A., Forsmark, C. E., Johnstone, M., Gardner, T. B., Gelrud, A., Greenhalf, W., Haines, J. L., Hartman, D. J., Hawes, R. A., Lawrence, C., Lewis, M., Mayerle, J., Mayeux, R., Melhem, N. M., Money, M. E., Muniraj, T., Papachristou, G. I., Pericak-Vance, M. A., Romagnuolo, J., Schellenberg, G. D., Sherman, S., Simon, P., Singh, V. P., Slivka, A., Stolz, D., Sutton, R., Weiss, F. U., Wilcox, C. M., Zarnescu, N. O., Wisniewski, S. R., O'Connell, M. R., Kienholz, M. L., Roeder, K., Barmada, M. M., Yadav, D., Devlin, B., Albert, M. S., Albin, R. L., Apostolova, L. G., Arnold, S. E., Baldwin, C. T., Barber, R., Barnes, L. L., Beach, T. G., Beecham, G. W., Beekly, D., Bennett, D. A., Bigio, E. H., Bird, T. D., Blacker, D., Boxer, A., Burke, J. R., Buxbaum, J. D., Cairns, N. J., Cantwell, L. B., Cao, C., Carney, R. M., Carroll, S. L., Chui, H. C., Clark, D. G., Cribbs, D. H., Crocco, E. A., Cruchaga, C., DeCarli, C., Demirci, F. Y., Dick, M., Dickson, D. W., Duara, R., Taner, N., Faber, K. M., Fallon, K. B., Farlow, M. R., Ferris, S., Foroud, T. M., Frosch, M. P., Galasko, D. R., Ganguli, M., Gearing, M., Geschwind, D. H., Ghetti, B., Gilbert, J. R., Gilman, S., Glass, J. D., Goate, A. M., Graff Radford, N. R., Green, R. C., Growdon, J. H., Hakonarson, H., Hamilton-Nelson, K. L., Hamilton, R. L., Harrell, L. E., Head, E., Honig, L. S., Hulette, C. M., Hyman, B. T., Jicha, G. A., Jin, L. W., Jun, G., Kamboh, M. I., Karydas, A., Kaye, J. A., Kim, R., Koo, E. H., Kowall, N. W., Kramer, J. H., Kramer, P., Kukul, W. A., LaFerla, F. M., Lah, J. J., Leverenz, J. B., Levey, A. I., Li, G., Lin, C. F., Lieberman, A. P., Lopez, O. L., Lunetta, K. L., Lyketsos, C. G., MacK, W. J., Marson, D. C., Martin, E. R., Martiniuk, F., Mash, D. C., Masliah, E., McKee, A. C., Mesulam, M., Miller, B. L., Miller, C. A., Miller, J. W., Montine, T. J., Morris, J. C., Murrel, J. R., Naj, A. C., Olichney, J. M., Parisi, J. E., Peskind, E., Petersen, R. C., Pierce, A., Poon, W. W., Potter, H., Quinn, J. F., Raj, A., Raskind, M., Reiman, E. M., Reisberg, B., Reitz, C., Ringman, J. M., Roberson, E. D., Rosen, H. J., Rosenberg, R. N., Sano, M., Saykin, A. J., Schneider, J. A., Schneider, L. S., Seeley, W. W., Smith, A. G., Sonnen, J. A., Spina, S., Stern, R. A., Tanzi, R. E., Trojanowski, J. Q., Troncoso, J. C., Tsuang, D. W., Valladares, O., Van Deerlin, V. M., Van Eldik, L. J., Vardarajan, B. N., Vinters, H. V., Vonsatte, J. P., Wang, L. S., Weintraub, S., Welsh-Bohmer, K. A., Williamson, J., Woltjer, R. L., Wright, C. B., Younkin, S. G., Yu, C. E. & Yu, L., Dec 2012, In : Nature Genetics. 44, 12, p. 1349-1354 6 p.

Research output: Contribution to journal › Article

Pancreatitis

Alcohols

Claudin-2

Hemizygote

Alleles

36 Citations (Scopus)

Comparison of imaging biomarkers in the Alzheimer Disease Neuroimaging Initiative and the Mayo Clinic Study of Aging

Whitwell, J. L., Wiste, H. J., Weigand, S. D., Rocca, W. A., Knopman, D. S., Roberts, R. O., Boeve, B. F., Petersen, R. C. & Jack, C. R. J., May 2012, In : Archives of Neurology. 69, 5, p. 614-622 9 p.

Research output: Contribution to journal › Article

Neuroimaging

Alzheimer Disease

Biomarkers

Population

Imaging

39 Citations (Scopus)

Computer activities, physical exercise, aging, and mild cognitive impairment: A population-based Study

Geda, Y. E., Silber, T. C., Roberts, R. O., Knopman, D. S., Christianson, T. J. H., Shane Pankratz, V., Boeve, B. F., Tangalos, E. G. & Petersen, R. C., 2012, In : Mayo Clinic Proceedings. 87, 5, p. 437-442 6 p.

Research output: Contribution to journal › Article

Exercise

Energy Intake

Population

Life Style

Logistic Models

11 Citations (Scopus)

Considerations in the design of clinical trials for cognitive aging

Reiman, E. M., Brinton, R. D., Katz, R., Petersen, R. C., Negash, S., Mungas, D. & Aisen, P. S., Jun 15 2012, In : Journals of Gerontology - Series A Biological Sciences and Medical Sciences. 67 A, 7, p. 766-772 7 p.

Research output: Contribution to journal › Article

Alzheimer Disease

Biomarkers

Clinical Trials

Research

Cognitive Aging

69 Citations (Scopus)

CSF biomarker and PIB-PET-derived beta-amyloid signature predicts metabolic, gray matter, and cognitive changes in nondemented subjects

Ewers, M., Insel, P., Jagust, W. J., Shaw, L., Trojanowski J, J. Q., Aisen, P., Petersen, R. C., Schuff, N. & Weiner, M. W., Sep 2012, In : Cerebral Cortex. 22, 9, p. 1993-2004 12 p.

Research output: Contribution to journal › Article

Amyloid

Positron-Emission Tomography

Biomarkers

Brain

Parietal Lobe

907 Citations (Scopus)

Diagnostic criteria for mild cognitive impairment in Parkinson's disease: Movement Disorder Society Task Force guidelines

Litvan, I., Goldman, J. G., Tröster, A. I., Schmand, B. A., Weintraub, D., Petersen, R. C., Mollenhauer, B., Adler, C. H., Marder, K., Williams-Gray, C. H., Aarsland, D., Kulisevsky, J., Rodriguez-Oroz, M. C., Burn, D. J., Barker, R. A. & Emre, M., Mar 2012, In : Movement Disorders. 27, 3, p. 349-356 8 p.

Research output: Contribution to journal › Article

Advisory Committees

Parkinson Disease

Guidelines

Dementia

Neurobiology

21 Citations (Scopus)

Diagnostic validity of age and education corrections for the mini-mental state examination in older African Americans

Pedraza, O. D., Clark, J. H., O'Bryant, S. E., Smith, G. E., Ivnik, R. J., Graff Radford, N. R., Willis, F. B., Petersen, R. C. & Lucas, J. A., Feb 2012, In : Journal of the American Geriatrics Society. 60, 2, p. 328-331 4 p.

Research output: Contribution to journal › Article

African Americans

Dementia

Education

Alzheimer Disease

Independent Living

91 Citations (Scopus)

Effect of lifestyle activities on alzheimer disease biomarkers and cognition

Vemuri, P. D., Lesnick, T. G., Przybelski, S. A., Knopman, D. S., Roberts, R. O., Lowe, V., Kantarci, K. M., Senjem, M. L., Gunter, J. L., Boeve, B. F., Petersen, R. C. & Jack, C. R. J., Nov 2012, In : Annals of Neurology. 72, 5, p. 730-738 9 p.

Research output: Contribution to journal › Article

Cognition

Life Style

Alzheimer Disease

Biomarkers

Positron-Emission Tomography

126 Citations (Scopus)

Evidence for a role of the rare p.A152T variant in mapt in increasing the risk for FTD-spectrum and Alzheimer's diseases

Coppola, G., Chinnathambi, S., Lee, J. J., Dombroski, B. A., Baker, M. C., Soto-ortolaza, A. I., Lee, S. E., Klein, E., Huang, A. Y., Sears, R., Lane, J. R., Karydas, A. M., Kenet, R. O., Biernat, J., Wang, L. S., Cotman, C. W., Decarli, C. S., Levey, A. I., Ringman, J. M., Mendez, M. F. & 210 others, Chui, H. C., Le ber, I., Brice, A., Lupton, M. K., Preza, E., Lovestone, S., Powell, J., Graff Radford, N. R., Petersen, R. C., Boeve, B. F., Lippa, C. F., Bigio, E. H., Mackenzie, I., Finger, E., Kertesz, A., Caselli, R. J., Gearing, M., Juncos, J. L., Ghetti, B., Spina, S., Bordelon, Y. M., Tourtellotte, W. W., Frosch, M. P., Vonsattel, J. P. G., Zarow, C., Beach, T. G., Albin, R. L., Lieberman, A. P., Lee, V. M., Trojanowski, J. Q., Van deerlin, V. M., Bird, T. D., Galasko, D. R., Masliah, E., White, C. L., Troncoso, J. C., Hannequin, D., Boxer, A. L., Geschwind, M. D., Kumar, S., Mandelkow, E. M., Wszolek, Z. K., Uitti, R. J., Dickson, D. W., Haines, J. L., Mayeux, R., Pericak-vance, M. A., Farrer, L. A., Apostolova, L. G., Arnold, S. E., Baldwin, C. T., Barber, R., Barmada, M. M., Beach, T., Beecham, G. W., Beekly, D., Bennett, D. A., Bigio, E. H., Bird, T. D., Blacker, D., Boeve, B. F., Bowen, J. D., Boxer, A., Burke, J. R., Buros, J., Buxbaum, J. D., Cairns, N. J., Cantwell, L. B., Cao, C., Carlson, C. S., Carney, R. M., Carrasquillo, M. M., Carroll, S. L., Chui, H. C., Clark, D. G., Corneveaux, J., Cotman, C. W., Crane, P. K., Cruchaga, C., Cummings, J. L., De Jager, P. L., DeCarli, C., DeKosky, S. T., Demirci, F. Y., Diaz-Arrastia, R., Dick, M., Dickson, D. W., Dombroski, B. A., Duara, R., Ellis, W. G., Taner, N., Evans, D., Faber, K. M., Fallon, K. B., Farlow, M. R., Ferris, S., Foroud, T. M., Frosch, M. P., Galasko, D. R., Gallins, P. J., Ganguli, M., Gearing, M., Geschwind, D. H., Ghetti, B., Gilbert, J. R., Gilman, S., Giordani, B., Glass, J. D., Goate, A. M., Graff-Radford, N. R., Green, R. C., Growdon, J. H., Hakonarson, H., Hamilton, R. L., Hardy, J., Harrell, L. E., Head, E., Honig, L. S., Huentelman, M. J., Hulette, C. M., Hyman, B. T., Jarvik, G. P., Jicha, G. A., Jin, L. W., Johnson, N., Jun, G., Kamboh, M. I., Karlawish, J., Karydas, A., Kauwe, J. S. K., Kaye, J. A., Kim, R., Koo, E. H., Kowall, N. W., Kramer, P., Kukull, W. A., Lah, J. J., Larson, E. B., Levey, A. I., Lieberman, A. P., Lopez, O. L., Lunetta, K. L., Mack, W. J., Marson, D. C., Martin, E. R., Martiniuk, F., Mash, D. C., Masliah, E., McCormick, W. C., McCurry, S. M., McDavid, A. N., McKee, A. C., Mesulam, M., Miller, B. L., Miller, C. A., Miller, J. W., Montine, T. J., Morris, J. C., Myers, A. J., Naj, A. C., Nowotny, P., Parisi, J. E., Perl, D. P., Peskind, E., Petersen, R. C., Poon, W. W., Potter, H., Quinn, J. F., Raj, A., Rajbhandary, R. A., Raskind, M., Reiman, E. M., Reisberg, B., Reitz, C., Ringman, J. M., Roberson, E. D., Rogaeva, E., Rosenberg, R. N., Sano, M., Saykin, A. J., Schneider, J. A., Schneider, L. S., Seeley, W., Shelanski, M. L., Slifer, M. A., Smith, C. D., Sonnen, J. A., Spina, S., George-Hyslop, P. S., Stern, R. A., Tanzi, R. E., Trojanowski, J. Q., Troncoso, J. C., Tsuang, D. W., Van Deerlin, V. M., Vardarajan, B. N., Vinters, H. V., Vonsattel, J. P., Wang, L. S., Weintraub, S., Welsh-Bohmer, K. A., Williamson, J., Woltjer, R. L., Younkin, S. G., Ross, O. A., Rademakers, R. V., Schellenberg, G. D., Miller, B. L., Mandelkow, E. & Geschwind, D. H., 2012, In : Human Molecular Genetics. 21, 15, p. 3500-3512 13 p., dds161.

Research output: Contribution to journal › Article

Progressive Supranuclear Palsy

Frontotemporal Dementia

Microtubule-Associated Proteins

Microtubules

tau Proteins

55 Citations (Scopus)

Focal atrophy on MRI and neuropathologic classification of dementia with Lewy bodies

Kantarci, K. M., Ferman, T. J., Boeve, B. F., Weigand, S. D., Przybelski, S., Vemuri, P. D., Murray, M. E., Senjem, M. L., Smith, G. E., Knopman, D. S., Petersen, R. C., Jack, C. R. J., Parisi, J. E. & Dickson, D. W., Aug 7 2012, In : Neurology. 79, 6, p. 553-560 8 p.

Research output: Contribution to journal › Article

Lewy Body Disease

Atrophy

Alzheimer Disease

Dementia

Lewy Bodies

Functional and genetic analysis of haplotypic sequence variation at the nicastrin genomic locus.

Hamilton, G., Killick, R., Genetic, N. V., Translational Genomics Research Institute Consortium, G. R. I. C., Lambert, J. C., Amouyel, P., European Alzheimer Disease Initiative, A. D. I., Carrasquillo, M. M., Pankratz, V. S., Graff-Radford, N. R., Dickson, D. W., Petersen, R. C., Younkin, S. G., Powell, J. F. & Wade-Martins, R., Aug 2012, In : Neurobiology of Aging. 33, 8

Research output: Contribution to journal › Article

Bacterial Artificial Chromosomes

Sequence Analysis

Haplotypes

Amyloid Precursor Protein Secretases

Alzheimer Disease

44 Citations (Scopus)

Genome-wide pathway analysis of memory impairment in the Alzheimer's Disease Neuroimaging Initiative (ADNI) cohort implicates gene candidates, canonical pathways, and networks

Ramanan, V. K., Kim, S., Holohan, K., Shen, L., Nho, K., Risacher, S. L., Foroud, T. M., Mukherjee, S., Crane, P. K., Aisen, P. S., Petersen, R. C., Weiner, M. W. & Saykin, A. J., 2012, In : Brain Imaging and Behavior. 6, 4, p. 634-648 15 p.

Research output: Contribution to journal › Article

Neuroimaging

Alzheimer Disease

Genome

Genes

Memory Disorders

42 Citations (Scopus)

Glutathione S-transferase omega genes in Alzheimer and Parkinson disease risk, age-at-diagnosis and brain gene expression: An association study with mechanistic implications

Allen, M., Zou, F., Chai, H. S., Younkin, C. S., Miles, R., Nair, A. A., Crook, J., Pankratz, V. S., Carrasquillo, M. M., Rowley, C. N., Nguyen, T., Ma, L., Malphrus, K. G., Bisceglio, G., Ortolaza, A. I., Palusak, R., Middha, S., Maharjan, S., Georgescu, C., Schultz, D. & 14 others, Rakhshan, F., Kolbert, C. P., Jen, J., Sando, S. B., Aasly, J. O., Barcikowska, M., Uitti, R. J., Wszolek, Z. K., Ross, O. A., Petersen, R. C., Graff Radford, N. R., Dickson, D. W., Younkin, S. G. & Taner, N., 2012, In : Molecular Neurodegeneration. 7, 1, 13.

Research output: Contribution to journal › Article

Glutathione Transferase

Parkinson Disease

Alzheimer Disease

Gene Expression

Brain

37 Citations (Scopus)

Imaging and acetylcholinesterase inhibitor response in dementia with Lewy bodies

Graff-Radford, J., Boeve, B. F., Pedraza, O. D., Ferman, T. J., Przybelski, S., Lesnick, T. G., Vemuri, P. D., Senjem, M. L., Smith, G. E., Knopman, D. S., Lowe, V., Jack, C. R. J., Petersen, R. C. & Kantarci, K. M., Aug 2012, In : Brain. 135, 8, p. 2470-2477 8 p.

Research output: Contribution to journal › Article

Lewy Body Disease

Cholinesterase Inhibitors

Positron-Emission Tomography

Dementia

Alzheimer Disease

92 Citations (Scopus)

Indicators of amyloid burden in a population-based study of cognitively normal elderly

Mielke, M. M., Wiste, H. J., Weigand, S. D., Knopman, D. S., Lowe, V., Roberts, R. O., Geda, Y. E., Swenson-Dravis, D. M., Boeve, B. F., Senjem, M. L., Vemuri, P. D., Petersen, R. C. & Jack, C. R. J., Oct 9 2012, In : Neurology. 79, 15, p. 1570-1577 8 p.

Research output: Contribution to journal › Article

Amyloid

Population

ROC Curve

Genotype

Amyloidosis

62 Citations (Scopus)

Length of normal alleles of C9ORF72 GGGGCC repeat do not influence disease phenotype

Rutherford, N. J., Heckman, M. G., DeJesus-Hernandez, M., Baker, M. C., Soto-Ortolaza, A. I., Rayaprolu, S., Stewart, H., Finger, E., Volkening, K., Seeley, W. W., Hatanpaa, K. J., Lomen-Hoerth, C., Kertesz, A., Bigio, E. H., Lippa, C., Knopman, D. S., Kretzschmar, H. A., Neumann, M., Caselli, R. J., White, C. L. & 12 others, Mackenzie, I. R., Petersen, R. C., Strong, M. J., Miller, B. L., Boeve, B. F., Uitti, R. J., Boylan, K. B., Wszolek, Z. K., Graff Radford, N. R., Dickson, D. W., Ross, O. A. & Rademakers, R. V., Dec 2012, In : Neurobiology of Aging. 33, 12

Research output: Contribution to journal › Article

Chromosomes, Human, Pair 9

Open Reading Frames

Alleles

Phenotype

Age of Onset

1 Citation (Scopus)

Limb immobilization and corticobasal syndrome

Graff-Radford, J., Boeve, B. F., Drubach, D., Knopman, D. S., Ahlskog, J. E., Golden, E. C., Drubach, D. I., Petersen, R. C. & Josephs, K. A., Dec 2012, In : Parkinsonism and Related Disorders. 18, 10, p. 1097-1099 3 p.

Research output: Contribution to journal › Article

Immobilization

Extremities

Wounds and Injuries

Age of Onset

Leg

Longitudinal study in cognition and aging

Edland, S. D. & Petersen, R. C., Jan 1 2012, Statistical and Process Models for Cognitive Neuroscience and Aging. Taylor and Francis, p. 1-14 14 p.

Research output: Chapter in Book/Report/Conference proceeding › Chapter

Cognition

Longitudinal Studies

Memory disorders

Geda, Y. E., Cockerill, R. & Petersen, R. C., Mar 28 2012, Principles and Practice of Geriatric Psychiatry. Wolters Kluwer Health Adis (ESP), p. 605-625 21 p.

Research output: Chapter in Book/Report/Conference proceeding › Chapter

Memory Disorders

Mild Cognitive Impairment

Tangalos, E. G. & Petersen, R. C., Mar 12 2012, Pathy's Principles and Practice of Geriatric Medicine: Fifth Edition. John Wiley and Sons, Vol. 2. p. 881-893 13 p.

Research output: Chapter in Book/Report/Conference proceeding › Chapter

Dementia

Executive Function

Activities of Daily Living

Research

Neuroimaging

110 Citations (Scopus)

Multimodality imaging characteristics of dementia with Lewy bodies

Kantarci, K. M., Lowe, V., Boeve, B. F., Weigand, S. D., Senjem, M. L., Przybelski, S. A., Dickson, D. W., Parisi, J. E., Knopman, D. S., Smith, G. E., Ferman, T. J., Petersen, R. C. & Jack, C. R. J., Sep 2012, In : Neurobiology of Aging. 33, 9, p. 2091-2105 15 p.

Research output: Contribution to journal › Article

Lewy Body Disease

Alzheimer Disease

Dementia

Positron-Emission Tomography

Atrophy

260 Citations (Scopus)

Mutations in the colony stimulating factor 1 receptor (CSF1R) gene cause hereditary diffuse leukoencephalopathy with spheroids

Rademakers, R. V., Baker, M., Nicholson, A. M., Rutherford, N. J., Finch, N., Soto-Ortolaza, A., Lash, J., Wider, C., Wojtas, A., Dejesus-Hernandez, M., Adamson, J., Kouri, N., Sundal, C., Shuster, E. A., Aasly, J., MacKenzie, J., Roeber, S., Kretzschmar, H. A., Boeve, B. F., Knopman, D. S. & 18 others, Petersen, R. C., Cairns, N. J., Ghetti, B., Spina, S., Garbern, J., Tselis, A. C., Uitti, R., Das, P., Van Gerpen, J. A., Meschia, J. F., Levy, S., Broderick, D. F., Graff Radford, N. R., Ross, O. A., Miller, B. B., Swerdlow, R. H., Dickson, D. W. & Wszolek, Z. K., Feb 2012, In : Nature Genetics. 44, 2, p. 200-205 6 p.

Research output: Contribution to journal › Article

Colony-Stimulating Factor Receptors

Macrophage Colony-Stimulating Factor

Mutation

Genes

Exome

154 Citations (Scopus)

Neuroimaging correlates of pathologically defined subtypes of Alzheimer's disease: A case-control study

Whitwell, J. L., Dickson, D. W., Murray, M. E., Weigand, S. D., Tosakulwong, N., Senjem, M. L., Knopman, D. S., Boeve, B. F., Parisi, J. E., Petersen, R. C., Jack, C. R. J. & Josephs, K. A., Oct 2012, In : The Lancet Neurology. 11, 10, p. 868-877 10 p.

Research output: Contribution to journal › Article

Neuroimaging

Case-Control Studies

Alzheimer Disease

Neurofibrillary Tangles

Atrophy

251 Citations (Scopus)

Neuroimaging signatures of frontotemporal dementia genetics: C9ORF72, tau, progranulin and sporadics

Whitwell, J. L., Weigand, S. D., Boeve, B. F., Senjem, M. L., Gunter, J. L., Dejesus-Hernandez, M., Rutherford, N. J., Baker, M., Knopman, D. S., Wszolek, Z. K., Parisi, J. E., Dickson, D. W., Petersen, R. C., Rademakers, R. V., Jack, C. R. J. & Josephs, K. A., Mar 2012, In : Brain. 135, 3, p. 794-806 13 p.

Research output: Contribution to journal › Article

Frontotemporal Dementia

Neuroimaging

Mutation

Atrophy

Atlases

5 Citations (Scopus)

New clinical criteria for the Alzheimer's disease spectrum.

Petersen, R. C., Jan 2012, In : Minnesota Medicine. 95, 1, p. 42-45 4 p.

Research output: Contribution to journal › Article

Alzheimer Disease

Biomarkers

Dementia

205 Citations (Scopus)

Non-stationarity in the "resting brain's" modular architecture

Jones, D. T., Vemuri, P. D., Murphy, M., Gunter, J. L., Senjem, M. L., Machulda, M. M., Przybelski, S. A., Gregg, B. E., Kantarci, K. M., Knopman, D. S., Boeve, B. F., Petersen, R. C. & Jack, C. R. J., Jun 28 2012, In : PLoS One. 7, 6, e39731.

Research output: Contribution to journal › Article

magnetic resonance imaging

Brain

dementia

brain

nervous system

89 Citations (Scopus)

Novel late-onset Alzheimer disease loci variants associate with brain gene expression

Allen, M., Zou, F., Chai, H. S., Younkin, C. S., Crook, J., Shane Pankratz, V., Carrasquillo, M. M., Rowley, C. N., Nair, A. A., Middha, S., Maharjan, S., Nguyen, T., Ma, L., Malphrus, K. G., Palusak, R., Lincoln, S., Bisceglio, G., Georgescu, C., Schultz, D., Rakhshan, F. & 12 others, Kolbert, C. P., Jen, J., Haines, J. L., Mayeux, R., Pericak-Vance, M. A., Farrer, L. A., Schellenberg, G. D., Petersen, R. C., Graff Radford, N. R., Dickson, D. W., Younkin, S. G. & Taner, N., Jul 17 2012, In : Neurology. 79, 3, p. 221-228 8 p.

Research output: Contribution to journal › Article

Alzheimer Disease

Gene Expression

Brain

Single Nucleotide Polymorphism

Genes

212 Citations (Scopus)

Prediction of conversion from mild cognitive impairment to Alzheimer's disease dementia based upon biomarkers and neuropsychological test performance

Ewers, M., Walsh, C., Trojanowski, J. Q., Shaw, L. M., Petersen, R. C., Jack, C. R. J., Feldman, H. H., Bokde, A. L. W., Alexander, G. E., Scheltens, P., Vellas, B., Dubois, B., Weiner, M. & Hampel, H., Jul 2012, In : Neurobiology of Aging. 33, 7

Research output: Contribution to journal › Article

Neuropsychological Tests

Alzheimer Disease

Biomarkers

Trail Making Test

Cerebrospinal Fluid

123 Citations (Scopus)

Probable rapid eye movement sleep behavior disorder increases risk for mild cognitive impairment and Parkinson disease: A population-based study

Boot, B. P., Boeve, B. F., Roberts, R. O., Ferman, T. J., Geda, Y. E., Pankratz, V. S., Ivnik, R. J., Smith, G. E., McDade, E., Christianson, T. J. H., Knopman, D. S., Tangalos, E. G., Silber, M. H. & Petersen, R. C., Jan 2012, In : Annals of Neurology. 71, 1, p. 49-56 8 p.

Research output: Contribution to journal › Article

REM Sleep Behavior Disorder

Parkinson Disease

Dementia

Population

Confidence Intervals

60 Citations (Scopus)

Relative intake of macronutrients impacts risk of mild cognitive impairment or dementia

Roberts, R. O., Roberts, L. A., Geda, Y. E., Cha, R. H., Pankratz, V. S., O'Connor, H. M., Knopman, D. S. & Petersen, R. C., 2012, In : Journal of Alzheimer's Disease. 32, 2, p. 329-339 11 p.

Research output: Contribution to journal › Article

Dementia

Energy Intake

Fats

Carbohydrates

Proteins

12 Citations (Scopus)

Reliable change on the Boston naming test

Sachs, B. C., Lucas, J. A., Smith, G. E., Ivnik, R. J., Petersen, R. C., Graff Radford, N. R. & Pedraza, O. D., Mar 2012, In : Journal of the International Neuropsychological Society. 18, 2, p. 375-378 4 p.

Research output: Contribution to journal › Article

Aptitude

human being

genealogy

dementia

Dementia