Ronald Carl Petersen, MD &ndash; Research Output

2014

APOE and BCHE as modulators of cerebral amyloid deposition: A florbetapir PET genome-wide association study

Ramanan, V. K., Risacher, S. L., Nho, K., Kim, S., Swaminathan, S., Shen, L., Foroud, T. M., Hakonarson, H., Huentelman, M. J., Aisen, P. S., Petersen, R. C., Green, R. C., Jack, C. R. J., Koeppe, R. A., Jagust, W. J., Weiner, M. W. & Saykin, A. J., Mar 2014, In : Molecular Psychiatry. 19, 3, p. 351-357 7 p.

Research output: Contribution to journal › Article

Butyrylcholinesterase

Genome-Wide Association Study

Apolipoproteins E

Amyloid

Positron-Emission Tomography

18 Citations (Scopus)

ApoE variant p.V236E is associated with markedly reduced risk of Alzheimer's disease

Medway, C. W., Abdul-Hay, S., Mims, T., Ma, L., Bisceglio, G., Zou, F., Pankratz, S., Sando, S. B., Aasly, J. O., Barcikowska, M., Siuda, J., Wszolek, Z. K., Ross, O. A., Carrasquillo, M. M., Dickson, D. W., Graff Radford, N. R., Petersen, R. C., Taner, N., Morgan, K., Bu, G. D. & 1 others, Younkin, S. G., Mar 10 2014, In : Molecular Neurodegeneration. 9, 1, 11.

Research output: Contribution to journal › Article

Apolipoproteins E

Alzheimer Disease

Exome

Alleles

Linkage Disequilibrium

59 Citations (Scopus)

A prospective study of chronic obstructive pulmonary disease and the risk for mild cognitive impairment

Singh, B., Mielke, M. M., Parsaik, A. K., Cha, R. H., Roberts, R. O., Scanlon, P. D., Geda, Y. E., Christianson, T. J., Pankratz, V. S. & Petersen, R. C., 2014, In : JAMA Neurology. 71, 5, p. 581-588 8 p.

Research output: Contribution to journal › Article

Chronic Obstructive Pulmonary Disease

Prospective Studies

Cognitive Dysfunction

Mild Cognitive Impairment

Medical Record Linkage

65 Citations (Scopus)

Association of diabetes with amnestic and nonamnestic mild cognitive impairment

Roberts, R. O., Knopman, D. S., Geda, Y. E., Cha, R. H., Pankratz, V. S., Baertlein, L., Boeve, B. F., Tangalos, E. G., Ivnik, R. J., Mielke, M. M. & Petersen, R. C., Jan 2014, In : Alzheimer's and Dementia. 10, 1, p. 18-26 9 p.

Research output: Contribution to journal › Article

Type 2 Diabetes Mellitus

Cognitive Dysfunction

Dementia

Alzheimer Disease

Vascular Diseases

47 Citations (Scopus)

Association of hypometabolism and amyloid levels in aging, normal subjects

Lowe, V., Weigand, S. D., Senjem, M. L., Vemuri, P. D., Jordan, L., Kantarci, K. M., Boeve, B. F., Jack, C. R. J., Knopman, D. S. & Petersen, R. C., Jun 3 2014, In : Neurology. 82, 22, p. 1959-1967 9 p.

Research output: Contribution to journal › Article

Amyloid

Alzheimer Disease

Fluorodeoxyglucose F18

2-(4'-(methylamino)phenyl)-6-hydroxybenzothiazole

Pittsburgh

74 Citations (Scopus)

Association of lifetime intellectual enrichment with cognitive decline in the older population

Vemuri, P. D., Lesnick, T. G., Przybelski, S. A., Machulda, M. M., Knopman, D. S., Mielke, M. M., Roberts, R. O., Geda, Y. E., Rocca, W. A., Petersen, R. C. & Jack, C. R. J., 2014, In : JAMA Neurology. 71, 8, p. 1017-1024 8 p.

Research output: Contribution to journal › Article

Occupations

Education

Population

Cognition

Dementia

47 Citations (Scopus)

Association of MAPT haplotypes with Alzheimer's disease risk and MAPT brain gene expression levels

Allen, M., Kachadoorian, M., Quicksall, Z., Zou, F., Chai, H. S., Younkin, C., Crook, J., Pankratz, V. S., Carrasquillo, M. M., Krishnan, S., Nguyen, T., Ma, L., Malphrus, K., Lincoln, S., Bisceglio, G., Kolbert, C. P., Jen, J., Mukherjee, S., Kauwe, J. K., Crane, P. K. & 11 others, Haines, J. L., Mayeux, R., Pericak-Vance, M. A., Farrer, L. A., Schellenberg, G. D., Parisi, J. E., Petersen, R. C., Graff Radford, N. R., Dickson, D. W., Younkin, S. G. & Taner, N., Jul 1 2014, In : Alzheimer's Research and Therapy. 6, 4, 39.

Research output: Contribution to journal › Article

Haplotypes

Alzheimer Disease

Gene Expression

Brain

Temporal Lobe

228 Citations (Scopus)

Association of Mediterranean diet with mild cognitive impairment and Alzheimer's disease: A systematic review and meta-analysis

Singh, B., Parsaik, A. K., Mielke, M. M., Erwin, P. J., Knopman, D. S., Petersen, R. C. & Roberts, R. O., 2014, In : Journal of Alzheimer's Disease. 39, 2, p. 271-282 12 p.

Research output: Contribution to journal › Article

Mediterranean Diet

Meta-Analysis

Alzheimer Disease

Confidence Intervals

Cohort Studies

24 Citations (Scopus)

Association of plasma and cortical amyloid beta is modulated by APOE ε4 status

Swaminathan, S., Risacher, S. L., Yoder, K. K., West, J. D., Shen, L., Kim, S., Inlow, M., Foroud, T., Jagust, W. J., Koeppe, R. A., Mathis, C. A., Shaw, L. M., Trojanowski, J. Q., Soares, H., Aisen, P. S., Petersen, R. C., Weiner, M. W. & Saykin, A. J., Jan 2014, In : Alzheimer's and Dementia. 10, 1

Research output: Contribution to journal › Article

Apolipoprotein E4

Amyloid

Apolipoproteins E

Alzheimer Disease

Alleles

88 Citations (Scopus)

Association of type 2 diabetes with brain atrophy and cognitive impairment

Roberts, R. O., Knopman, D. S., Przybelski, S. A., Mielke, M. M., Kantarci, K. M., Preboske, G. M., Senjem, M. L., Pankratz, V. S., Geda, Y. E., Boeve, B. F., Ivnik, R. J., Rocca, W. A., Petersen, R. C. & Jack, C. R. J., Apr 1 2014, In : Neurology. 82, 13, p. 1132-1141 10 p.

Research output: Contribution to journal › Article

Type 2 Diabetes Mellitus

Atrophy

Hypertension

Cognition

Brain

52 Citations (Scopus)

Ataxin-2 as potential disease modifier in C9ORF72 expansion carriers

Van Blitterswijk, M., Mullen, B., Heckman, M. G., Baker, M. C., DeJesus-Hernandez, M., Brown, P. H., Murray, M. E., Hsiung, G. Y. R., Stewart, H., Karydas, A. M., Finger, E., Kertesz, A., Bigio, E. H., Weintraub, S., Mesulam, M., Hatanpaa, K. J., White, C. L., Neumann, M., Strong, M. J., Beach, T. G. & 17 others, Wszolek, Z. K., Lippa, C., Caselli, R. J., Petrucelli, L., Josephs, K. A., Parisi, J. E., Knopman, D. S., Petersen, R. C., Mackenzie, I. R., Seeley, W. W., Grinberg, L. T., Miller, B. L., Boylan, K. B., Graff Radford, N. R., Boeve, B. F., Dickson, D. W. & Rademakers, R. V., 2014, In : Neurobiology of Aging. 35, 10

Research output: Contribution to journal › Article

Chromosomes, Human, Pair 9

Open Reading Frames

Motor Neuron Disease

Motor Neurons

Angelman Syndrome

107 Citations (Scopus)

Baseline neuropsychiatric symptoms and the risk of incident mild cognitive impairment: A population-based study

Geda, Y. E., Roberts, R. O., Mielke, M. M., Knopman, D. S., Christianson, T. J. H., Pankratz, V. S., Boeve, B. F., Sochor, O., Tangalos, E. G., Petersen, R. C. & Rocca, W. A., May 1 2014, In : American Journal of Psychiatry. 171, 5, p. 572-581 10 p.

Research output: Contribution to journal › Article

Population

Psychiatry

Cognitive Dysfunction

Mild Cognitive Impairment

Depression

116 Citations (Scopus)

Classifying neurocognitive disorders: The DSM-5 approach

Sachdev, P. S., Blacker, D., Blazer, D. G., Ganguli, M., Jeste, D. V., Paulsen, J. S. & Petersen, R. C., Nov 5 2014, In : Nature Reviews Neurology. 10, 11, p. 634-642 9 p.

Research output: Contribution to journal › Article

Cerebrovascular Disorders

Lewy Body Disease

Delirium

Diagnostic and Statistical Manual of Mental Disorders

Alcoholism

66 Citations (Scopus)

Dementia with Lewy bodies: Basis of cingulate island sign

Graff-Radford, J., Murray, M. E., Lowe, V., Boeve, B. F., Ferman, T. J., Przybelski, S. A., Lesnick, T. G., Senjem, M. L., Gunter, J. L., Smith, G. E., Knopman, D. S., Jack, C. R. J., Dickson, D. W., Petersen, R. C. & Kantarci, K. M., 2014, In : Neurology. 83, 9, p. 801-809 9 p.

Research output: Contribution to journal › Article

Lewy Body Disease

Islands

Neurofibrillary Tangles

Alzheimer Disease

Amyloid

77 Citations (Scopus)

Diabetes and elevated hemoglobin a1c levels are associated with brain hypometabolism but not amyloid accumulation

Roberts, R. O., Knopman, D. S., Cha, R. H., Mielke, M. M., Pankratz, V. S., Boeve, B. F., Kantarci, K. M., Geda, Y. E., Jack, C. R. J., Petersen, R. C. & Lowe, V., May 1 2014, In : Journal of Nuclear Medicine. 55, 5, p. 759-764 6 p.

Research output: Contribution to journal › Article

Amyloid

Fluorodeoxyglucose F18

Alzheimer Disease

Hemoglobins

Brain

53 Citations (Scopus)

Early Alzheimer’s disease neuropathology detected by proton MR spectroscopy

Murray, M. E., Przybelski, S. A., Lesnick, T. G., Liesinger, A. M., Spychalla, A., Zhang, B., Gunter, J. L., Parisi, J. E., Boeve, B. F., Knopman, D. S., Petersen, R. C., Jack, C. R. J., Dickson, D. W. & Kantarci, K. M., Dec 3 2014, In : Journal of Neuroscience. 34, 49, p. 16247-16255 9 p.

Research output: Contribution to journal › Article

Creatine

Protons

Gyrus Cinguli

Alzheimer Disease

Inositol

83 Citations (Scopus)

Effects of multiple genetic loci on age at onset in late-onset Alzheimer disease: A genome-wide association study

Alzheimer Disease Genetics Consortium, Nov 1 2014, In : JAMA Neurology. 71, 11, p. 1394-1404 11 p.

Research output: Contribution to journal › Article

Genetic Loci

Genome-Wide Association Study

Age of Onset

Alzheimer Disease

Genetic Databases

24 Citations (Scopus)

Effects of traumatic brain injury and posttraumatic stress disorder on Alzheimer's disease in veterans, using the Alzheimer's Disease Neuroimaging Initiative

Weiner, M. W., Veitch, D. P., Hayes, J., Neylan, T., Grafman, J., Aisen, P. S., Petersen, R. C., Jack, C. R. J., Jagust, W., Trojanowski, J. Q., Shaw, L. M., Saykin, A. J., Green, R. C., Harvey, D., Toga, A. W., Friedl, K. E., Pacifico, A., Sheline, Y., Yaffe, K. & Mohlenoff, B., 2014, In : Alzheimer's and Dementia. 10, 3 SUPPL.

Research output: Contribution to journal › Article

Veterans

Post-Traumatic Stress Disorders

Neuroimaging

Alzheimer Disease

Dementia

29 Citations (Scopus)

Evaluation of memory endophenotypes for association with CLU, CR1, and PICALM variants in black and white subjects

Pedraza, O. D., Allen, M., Jennette, K., Carrasquillo, M. M., Crook, J., Serie, D., Pankratz, V. S., Palusak, R., Nguyen, T., Malphrus, K., Ma, L., Bisceglio, G., Roberts, R. O., Lucas, J. A., Ivnik, R. J., Smith, G. E., Graff Radford, N. R., Petersen, R. C., Younkin, S. G. & Taner, N., 2014, In : Alzheimer's and Dementia. 10, 2, p. 205-213 9 p.

Research output: Contribution to journal › Article

Endophenotypes

Alzheimer Disease

Short-Term Memory

Reproduction

Single Nucleotide Polymorphism

118 Citations (Scopus)

Frontotemporal dementia and its subtypes: A genome-wide association study

Ferrari, R., Hernandez, D. G., Nalls, M. A., Rohrer, J. D., Ramasamy, A., Kwok, J. B. J., Dobson-Stone, C., Brooks William S., B. S., Schofield, P. R., Halliday, G. M., Hodges, J. R., Piguet, O., Bartley, L., Thompson, E., Haan, E., Hernández, I., Ruiz, A., Boada, M., Borroni, B., Padovani, A. & 138 others, Cruchaga, C., Cairns, N. J., Benussi, L., Binetti, G., Ghidoni, R., Forloni, G., Galimberti, D., Fenoglio, C., Serpente, M., Scarpini, E., Clarimón, J., Lleó, A., Blesa, R., Waldö, M. L., Nilsson, K., Nilsson, C., Mackenzie, I. R. A., Hsiung, G. Y. R., Mann, D. M. A., Grafman, J., Morris, C. M., Attems, J., Griffiths, T. D., McKeith, I. G., Thomas, A. J., Pietrini, P., Huey, E. D., Wassermann, E. M., Baborie, A., Jaros, E., Tierney, M. C., Pastor, P., Razquin, C., Ortega-Cubero, S., Alonso, E., Perneczky, R., Diehl-Schmid, J., Alexopoulos, P., Kurz, A., Rainero, I., Rubino, E., Pinessi, L., Rogaeva, E., St George-Hyslop, P., Rossi, G., Tagliavini, F., Giaccone, G., Rowe, J. B., Schlachetzki, J. C. M., Uphill, J., Collinge, J., Mead, S., Danek, A., Van Deerlin, V. M., Grossman, M., Trojanowski, J. Q., Van der Zee, J., Deschamps, W., Van Langenhove, T., Cruts, M., Van Broeckhoven, C., Cappa, S. F., Le Ber, I., Hannequin, D., Golfier, V., Vercelletto, M., Brice, A., Nacmias, B., Sorbi, S., Bagnoli, S., Piaceri, I., Nielsen, J. E., Hjermind, L. E., Riemenschneider, M., Mayhaus, M., Ibach, B., Gasparoni, G., Pichler, S., Gu, W., Rossor, M. N., Fox, N. C., Warren, J. D., Spillantini, M. G., Morris, H. R., Rizzu, P., Heutink, P., Snowden, J. S., Rollinson, S., Richardson, A., Gerhard, A., Bruni, A. C., Maletta, R., Frangipane, F., Cupidi, C., Bernardi, L., Anfossi, M., Gallo, M., Conidi, M. E., Smirne, N., Rademakers, R. V., Baker, M., Dickson, D. W., Graff Radford, N. R., Petersen, R. C., Knopman, D. S., Josephs, K. A., Boeve, B. F., Parisi, J. E., Seeley, W. W., Miller, B. L., Karydas, A. M., Rosen, H., van Swieten, J. C., Dopper, E. G. P., Seelaar, H., Pijnenburg, Y. A. L., Scheltens, P., Logroscino, G., Capozzo, R., Novelli, V., Puca, A. A., Franceschi, M., Postiglione, A., Milan, G., Sorrentino, P., Kristiansen, M., Chiang, H. H., Graff, C., Pasquier, F., Rollin, A., Deramecourt, V., Lebert, F., Kapogiannis, D., Ferrucci, L., Pickering-Brown, S., Singleton, A. B., Hardy, J. & Momeni, P., 2014, In : The Lancet Neurology. 13, 7, p. 686-699 14 p.

Research output: Contribution to journal › Article

Frontotemporal Dementia

Genome-Wide Association Study

Methylation

Joints

Quantitative Trait Loci

33 Citations (Scopus)

Genetic modifiers in carriers of repeat expansions in the C9ORF72 gene

Van Blitterswijk, M., Mullen, B., Wojtas, A., Heckman, M. G., Diehl, N. N., Baker, M. C., DeJesus-Hernandez, M., Brown, P. H., Murray, M. E., Hsiung, G. Y. R., Stewart, H., Karydas, A. M., Finger, E., Kertesz, A., Bigio, E. H., Weintraub, S., Mesulam, M., Hatanpaa, K. J., White, C. L., Neumann, M. & 19 others, Strong, M. J., Beach, T. G., Wszolek, Z. K., Lippa, C., Caselli, R. J., Petrucelli, L., Josephs, K. A., Parisi, J. E., Knopman, D. S., Petersen, R. C., Mackenzie, I. R., Seeley, W. W., Grinberg, L. T., Miller, B. L., Boylan, K. B., Graff Radford, N. R., Boeve, B. F., Dickson, D. W. & Rademakers, R. V., 2014, In : Molecular Neurodegeneration. 9, p. 38 1 p.

Research output: Contribution to journal › Article

Frontotemporal Dementia

Motor Neuron Disease

Chromosomes, Human, Pair 9

Open Reading Frames

Age of Onset

33 Citations (Scopus)

Genome-wide association interaction analysis for Alzheimer's disease

GERAD1 Consortium, Nov 1 2014, In : Neurobiology of Aging. 35, 11, p. 2436-2443 8 p.

Research output: Contribution to journal › Article

Genome-Wide Association Study

Alzheimer Disease

Gene Expression Profiling

Temporal Lobe

Cerebellum

27 Citations (Scopus)

Head trauma and in vivo measures of amyloid and neurodegeneration in a population-based study

Mielke, M. M., Savica, R., Wiste, H. J., Weigand, S. D., Vemuri, P. D., Knopman, D. S., Lowe, V., Roberts, R. O., Machulda, M. M., Geda, Y. E., Petersen, R. C. & Jack, C. R. J., Jan 7 2014, In : Neurology. 82, 1, p. 70-76 7 p.

Research output: Contribution to journal › Article

Craniocerebral Trauma

Amyloid

Population

Unconsciousness

Neuroimaging

147 Citations (Scopus)

Higher risk of progression to dementia in mild cognitive impairment cases who revert to normal

Roberts, R. O., Knopman, D. S., Mielke, M. M., Cha, R. H., Pankratz, V. S., Christianson, T. J. H., Geda, Y. E., Boeve, B. F., Ivnik, R. J., Tangalos, E. G., Rocca, W. A. & Petersen, R. C., Jan 28 2014, In : Neurology. 82, 4, p. 317-325 9 p.

Research output: Contribution to journal › Article

Dementia

Cognitive Dysfunction

Mild Cognitive Impairment

Progression

Hazard

30 Citations (Scopus)

Hypothyroidism and risk of mild cognitive impairment in elderly persons a population-based study

Parsaik, A. K., Singh, B., Roberts, R. O., Pankratz, S., Edwards, K. K., Geda, Y. E., Gharib, H., Boeve, B. F., Knopman, D. S. & Petersen, R. C., Feb 2014, In : JAMA Neurology. 71, 2, p. 201-207 7 p.

Research output: Contribution to journal › Article

Hypothyroidism

Population

Dementia

Medical Record Linkage

Apolipoprotein E4

87 Citations (Scopus)

Improved DTI registration allows voxel-based analysis that outperforms Tract-Based Spatial Statistics

Schwarz, C., Reid, R. I., Gunter, J. L., Senjem, M. L., Przybelski, S. A., Zuk, S. M., Whitwell, J. L., Vemuri, P. D., Josephs, K. A., Kantarci, K. M., Thompson, P. M., Petersen, R. C. & Jack, C. R. J., Jul 1 2014, In : NeuroImage. 94, p. 65-78 14 p.

Research output: Contribution to journal › Article

Skeleton

Anisotropy

Progressive Supranuclear Palsy

Alzheimer Disease

Software

13 Citations (Scopus)

Incidence of dementia among participants and nonparticipants in a longitudinal study of cognitive aging

Knopman, D. S., Roberts, R. O., Pankratz, V. S., Cha, R. H., Rocca, W. A., Mielke, M. M., Boeve, B. F., Tangalos, E. G., Ivnik, R. J., Geda, Y. E. & Petersen, R. C., 2014, In : American Journal of Epidemiology. 180, 4, p. 414-423 10 p.

Research output: Contribution to journal › Article

Longitudinal Studies

Dementia

Incidence

Medical Record Linkage

Sex Education

14 Citations (Scopus)

Independent comparison of CogState computerized testing and a standard cognitive battery with neuroimaging

Mielke, M. M., Weigand, S. D., Wiste, H. J., Vemuri, P. D., Machulda, M. M., Knopman, D. S., Lowe, V., Roberts, R. O., Kantarci, K. M., Rocca, W. A., Jack, C. R. J. & Petersen, R. C., Nov 1 2014, In : Alzheimer's and Dementia. 10, 6, p. 779-789 11 p.

Research output: Contribution to journal › Article

Neuroimaging

Neuropsychological Tests

Amyloid

Positron-Emission Tomography

Maze Learning

32 Citations (Scopus)

Late-onset Alzheimer disease ge

Carrasquillo, M. M., Khan, Q. U. A., Murray, M. E., Krishnan, S., Aakre, J., Pankratz, V. S., Nguyen, T., Ma, L., Bisceglio, G., Petersen, R. C., Younkin, S. G., Dickson, D. W., Boeve, B. F., Graff Radford, N. R. & Taner, N., Apr 22 2014, In : Neurology. 82, 16, p. 1455-1462 8 p.

Research output: Contribution to journal › Article

Alzheimer Disease

Atrophy

Odds Ratio

Single Nucleotide Polymorphism

Onset

398 Citations (Scopus)

Mild cognitive impairment: A concept in evolution

Petersen, R. C., Caracciolo, B., Brayne, C., Gauthier, S., Jelic, V. & Fratiglioni, L., 2014, In : Journal of Internal Medicine. 275, 3, p. 214-228 15 p.

Research output: Contribution to journal › Article

Biomarkers

Population

Patient Selection

Longitudinal Studies

Dementia

41 Citations (Scopus)

Mild cognitive impairment and mild dementia: A clinical perspective

Knopman, D. S. & Petersen, R. C., Oct 1 2014, In : Mayo Clinic Proceedings. 89, 10, p. 1452-1459 8 p.

Research output: Contribution to journal › Article

Dementia

Alzheimer Disease

Cognitive Dysfunction

Pharmacology

Cerebrovascular Disorders

2 Citations (Scopus)

Predictors of early-onset cognitive impairment

Roberts, R. O. & Petersen, R. C., 2014, In : Brain. 137, 5, p. 1280-1281 2 p.

Research output: Contribution to journal › Article

Cognition Disorders

Physical Fitness

Dementia

Cognitive Dysfunction

Cognitive Impairment

41 Citations (Scopus)

Progranulin protein levels are differently regulated in plasma and CSF

Nicholson, A. M., Finch, N. A., Thomas, C. S., Wojtas, A., Rutherford, N. J., Mielke, M. M., Roberts, R. O., Boeve, B. F., Knopman, D. S., Petersen, R. C. & Rademakers, R. V., May 27 2014, In : Neurology. 82, 21, p. 1871-1878 8 p.

Research output: Contribution to journal › Article

Proteins

Single Nucleotide Polymorphism

Plasma

Protein

Linear Models

1 Citation (Scopus)

Quantitative characterization of brain β-amyloid using a joint PiB/FDG PET image histogram

Camp, J. J., Hanson, D. P., Holmes III, D. R., Kemp, B. J., Senjem, M. L., Murray, M. E., Dickson, D. W., Parisi, J. E., Petersen, R. C., Lowe, V. & Robb, R. A., 2014, Progress in Biomedical Optics and Imaging - Proceedings of SPIE. SPIE, Vol. 9035. 90352A

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Fluorodeoxyglucose F18

Amyloid

histograms

brain

Brain

88 Citations (Scopus)

Rates of β-amyloid accumulation are independent of hippocampal neurodegeneration

Jack, C. R. J., Wiste, H. J., Knopman, D. S., Vemuri, P. D., Mielke, M. M., Weigand, S. D., Senjem, M. L., Gunter, J. L., Lowe, V., Gregg, B. E., Pankratz, V. S. & Petersen, R. C., May 6 2014, In : Neurology. 82, 18, p. 1605-1612 8 p.

Research output: Contribution to journal › Article

Amyloid

Atrophy

Alzheimer Disease

Brain

National Institute on Aging (U.S.)

55 Citations (Scopus)

Regional distribution of synaptic markers and APP correlate with distinct clinicopathological features in sporadic and familial Alzheimer's disease

Shinohara, M., Fujioka, S., Murray, M. E., Wojtas, A., Baker, M., Rovelet-Lecrux, A., Rademakers, R. V., Das, P., Parisi, J. E., Graff Radford, N. R., Petersen, R. C., Dickson, D. W. & Bu, G. D., 2014, In : Brain. 137, 5, p. 1533-1549 17 p.

Research output: Contribution to journal › Article

Amyloid beta-Protein Precursor

Amyloid

Alzheimer Disease

Alzheimer's Disease

Familial

13 Citations (Scopus)

Regional proton magnetic resonance spectroscopy patterns in dementia with Lewy bodies

Graff-Radford, J., Boeve, B. F., Murray, M. E., Ferman, T. J., Tosakulwong, N., Lesnick, T. G., Maroney-Smith, M., Senjem, M. L., Gunter, J., Smith, G. E., Knopman, D. S., Jack, C. R. J., Dickson, D. W., Petersen, R. C. & Kantarci, K. M., Jun 2014, In : Neurobiology of Aging. 35, 6, p. 1483-1490 8 p.

Research output: Contribution to journal › Article

Lewy Body Disease

Alzheimer Disease

Creatine

Gyrus Cinguli

Magnetic Resonance Spectroscopy

18 Citations (Scopus)

Short and long telomeres increase risk of amnestic mild cognitive impairment

Roberts, R. O., Boardman, L. A., Cha, R. H., Pankratz, V. S., Johnson, R. A., Druliner, B. R., Christianson, T. J. H., Roberts, L. R. & Petersen, R. C., Nov 1 2014, In : Mechanisms of Ageing and Development. 141-142, p. 64-69 6 p.

Research output: Contribution to journal › Article

Telomere

Alzheimer Disease

Confidence Intervals

Cognitive Dysfunction

Polymerase Chain Reaction

127 Citations (Scopus)

Staging TDP-43 pathology in Alzheimer's disease

Josephs, K. A., Murray, M. E., Whitwell, J. L., Parisi, J. E., Petrucelli, L., Jack, C. R. J., Petersen, R. C. & Dickson, D. W., Mar 2014, In : Acta Neuropathologica. 127, 3, p. 441-450 10 p.

Research output: Contribution to journal › Article

Alzheimer Disease

Amygdala

Pathology

Hippocampus

Dentate Gyrus

Statement of Ronald C. Petersen, director, Mayo Alzheimer's disease research center. hearing on "the national plan to address Alzheimer's disease: Are we on track to 2025?"

Petersen, R. C., Apr 1 2014, National Plan to Address Alzheimer's Disease: Goals and Progress. Nova Science Publishers, Inc., p. 89-95 7 p.

Research output: Chapter in Book/Report/Conference proceeding › Chapter

dementia

director

15 Citations (Scopus)

TDP-43 in Alzheimer's disease is not associated with clinical FTLD or Parkinsonism

Jung, Y., Dickson, D. W., Murray, M. E., Whitwell, J. L., Knopman, D. S., Boeve, B. F., Jack, C. R. J., Parisi, J. E., Petersen, R. C. & Josephs, K. A., 2014, In : Journal of Neurology. 261, 7, p. 1344-1348 5 p.

Research output: Contribution to journal › Article

Frontotemporal Lobar Degeneration

Parkinsonian Disorders

Basal Ganglia

Alzheimer Disease

Substantia Nigra

132 Citations (Scopus)

TDP-43 is a key player in the clinical features associated with Alzheimer's disease

Josephs, K. A., Whitwell, J. L., Weigand, S. D., Murray, M. E., Tosakulwong, N., Liesinger, A. M., Petrucelli, L., Senjem, M. L., Knopman, D. S., Boeve, B. F., Ivnik, R. J., Smith, G. E., Jack, C. R. J., Parisi, J. E., Petersen, R. C. & Dickson, D. W., 2014, In : Acta Neuropathologica. 127, 6, p. 811-824 14 p.

Research output: Contribution to journal › Article

Alzheimer Disease

Atrophy

Cognition

Pathology

Apolipoproteins

13 Citations (Scopus)

The GGGGCC Repeat Expansion in C9ORF72 in a Case with Discordant Clinical and FDG-PET Findings: PET Trumps Syndrome

Adeli, A., Savica, R., Lowe, V., Vemuri, P. D., Knopman, D. S., DeJesus-Hernandez, M., Rademakers, R. V., Fields, J. A., Crum, B. A., Jack, C. R. J., Petersen, R. C. & Boeve, B. F., Jan 2014, In : Neurocase. 20, 1, p. 110-120 11 p.

Research output: Contribution to journal › Article

Chromosomes, Human, Pair 9

Amyotrophic Lateral Sclerosis

Open Reading Frames

Alzheimer Disease

Temporal Lobe

78 Citations (Scopus)

TMEM106B protects C9ORF72 expansion carriers against frontotemporal dementia

Van Blitterswijk, M., Mullen, B., Nicholson, A. M., Bieniek, K. F., Heckman, M. G., Baker, M. C., Dejesus-Hernandez, M., Finch, N. A., Brown, P. H., Murray, M. E., Hsiung, G. Y. R., Stewart, H., Karydas, A. M., Finger, E., Kertesz, A., Bigio, E. H., Weintraub, S., Mesulam, M., Hatanpaa, K. J., White, C. L. & 19 others, Strong, M. J., Beach, T. G., Wszolek, Z. K., Lippa, C., Caselli, R. J., Petrucelli, L., Josephs, K. A., Parisi, J. E., Knopman, D. S., Petersen, R. C., Mackenzie, I. R., Seeley, W. W., Grinberg, L. T., Miller, B. L., Boylan, K. B., Graff Radford, N. R., Boeve, B. F., Dickson, D. W. & Rademakers, R. V., Mar 2014, In : Acta Neuropathologica. 127, 3, p. 397-406 10 p.

Research output: Contribution to journal › Article

Frontotemporal Dementia

Chromosomes, Human, Pair 9

Open Reading Frames

Motor Neuron Disease

Odds Ratio

19 Citations (Scopus)

Use of diuretics is associated with reduced risk of Alzheimer's disease: The Cache County study

Cache County Investigators, Nov 1 2014, In : Neurobiology of Aging. 35, 11, p. 2429-2435 7 p.

Research output: Contribution to journal › Article

Diuretics

Alzheimer Disease

Potassium Sparing Diuretics

Antihypertensive Agents

Thiazides

26 Citations (Scopus)

White matter integrity determined with diffusion tensor imaging in older adults without dementia: Influence of amyloid load and neurodegeneration

Kantarci, K. M., Schwarz, C., Reid, R. I., Przybelski, S. A., Lesnick, T. G., Zuk, S. M., Senjem, M. L., Gunter, J. L., Lowe, V., Machulda, M. M., Knopman, D. S., Petersen, R. C. & Jack, C. R. J., Dec 1 2014, In : JAMA Neurology. 71, 12, p. 1547-1554 8 p.

Research output: Contribution to journal › Article

Diffusion Tensor Imaging

Amyloid

Dementia

Anisotropy

Biomarkers

2013

20 Citations (Scopus)

Age and apolipoprotein E genotype influence rate of cognitive decline in nondemented elderly

Salmon, D. P., Ferris, S. H., Thomas, R. G., Sano, M., Cummings, J. L., Sperling, R. A., Petersen, R. C. & Aisen, P. S., Jul 2013, In : Neuropsychology. 27, 4, p. 391-401 11 p.

Research output: Contribution to journal › Article

Apolipoproteins E

Alzheimer Disease

Genotype

Primary Prevention

Apolipoprotein E4

119 Citations (Scopus)

Amyloid-first and neurodegeneration-first profiles characterize incident amyloid PET positivity

Jack, C. R. J., Wiste, H. J., Weigand, S. D., Knopman, D. S., Lowe, V., Vemuri, P. D., Mielke, M. M., Jones, D. T., Senjem, M. L., Gunter, J. L., Gregg, B. E., Pankratz, V. S. & Petersen, R. C., Nov 12 2013, In : Neurology. 81, 20, p. 1732-1740 9 p.

Research output: Contribution to journal › Article

Amyloid

Positivity

Alzheimer Disease

Imaging

Incidence

33 Citations (Scopus)

Application of the national institute on aging-alzheimer's association AD criteria to ADNI

Lowe, V., Peller, P. J., Weigand, S. D., Quintero, C. M., Tosakulwong, N., Vemuri, P. D., Senjem, M. L., Jordan, L., Jack, C. R. J., Knopman, D. S. & Petersen, R. C., Jun 4 2013, In : Neurology. 80, 23, p. 2130-2137 8 p.

Research output: Contribution to journal › Article

National Institute on Aging (U.S.)

Neuroimaging

Alzheimer Disease

Biomarkers

Amyloid

167 Citations (Scopus)

Assessing the temporal relationship between cognition and gait: Slow gait predicts cognitive decline in the mayo clinic study of aging

Mielke, M. M., Roberts, R. O., Savica, R., Cha, R., Drubach, D. I., Christianson, T., Pankratz, V. S., Geda, Y. E., Machulda, M. M., Ivnik, R. J., Knopman, D. S., Boeve, B. F., Rocca, W. A. & Petersen, R. C., Aug 2013, In : Journals of Gerontology - Series A Biological Sciences and Medical Sciences. 68, 8, p. 929-937 9 p.

Research output: Contribution to journal › Article

Gait

Cognition

Executive Function

Cognitive Dysfunction

Walking Speed