• 124938 Citations
  • 157 Scopus h-Index
1974 …2020

Research output per year

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Research Output

Genetic variation across RNA metabolism and cell death gene networks is implicated in the semantic variant of primary progressive aphasia

International FTD-Genomics Consortium (IFGC), Dec 1 2019, In : Scientific reports. 9, 1, 10854.

Research output: Contribution to journalArticle

Open Access

Genetic variation in PCDH11X is associated with susceptibility to late onset alzheimer's disease

Carrasquillo, M. M., Zou, F., Pankratz, V. S., Wilcox, S. L., Ma, L., Walker, L. P., Younkin, C. S., Younkin, L. H., Bisceglio, G. D., Ertekin-Taner, N., Crook, J. E., Dickson, D. W., Petersen, R. C., Graff-Radford, N. R. & Younkin, S. G., Jul 8 2010, In : Hirosaki Medical Journal. 61, SUPPL., p. S125-S134

Research output: Contribution to journalArticle

Genetic variation in PCDH11X is associated with susceptibility to late-onset Alzheimer's disease

Carrasquillo, M. M., Zou, F., Pankratz, V. S., Wilcox, S. L., Ma, L., Walker, L. P., Younkin, S. G., Younkin, C. S., Younkin, L. H., Bisceglio, G. D., Ertekin-Taner, N., Crook, J. E., Dickson, D. W., Petersen, R. C., Graff-Radford, N. R. & Younkin, S. G., Feb 2009, In : Nature Genetics. 41, 2, p. 192-198 7 p.

Research output: Contribution to journalArticle

213 Scopus citations

Genome-wide, high-content siRNA screening identifies the Alzheimer’s genetic risk factor FERMT2 as a major modulator of APP metabolism

ADGC, Alzheimer’s Disease Neuroimaging Initiative, Jun 1 2017, In : Acta neuropathologica. 133, 6, p. 955-966 12 p.

Research output: Contribution to journalArticle

16 Scopus citations

Genome-wide analyses as part of the international FTLD-TDP whole-genome sequencing consortium reveals novel disease risk factors and increases support for immune dysfunction in FTLD

Pottier, C., Ren, Y., Perkerson, R. B., Baker, M., Jenkins, G. D., van Blitterswijk, M., DeJesus-Hernandez, M., van Rooij, J. G. J., Murray, M. E., Christopher, E., McDonnell, S. K., Fogarty, Z., Batzler, A., Tian, S., Vicente, C. T., Matchett, B., Karydas, A. M., Hsiung, G. Y. R., Seelaar, H., Mol, M. O. & 85 others, Finger, E. C., Graff, C., Öijerstedt, L., Neumann, M., Heutink, P., Synofzik, M., Wilke, C., Prudlo, J., Rizzu, P., Simon-Sanchez, J., Edbauer, D., Roeber, S., Diehl-Schmid, J., Evers, B. M., King, A., Mesulam, M. M., Weintraub, S., Geula, C., Bieniek, K. F., Petrucelli, L., Ahern, G. L., Reiman, E. M., Woodruff, B. K., Caselli, R. J., Huey, E. D., Farlow, M. R., Grafman, J., Mead, S., Grinberg, L. T., Spina, S., Grossman, M., Irwin, D. J., Lee, E. B., Suh, E. R., Snowden, J., Mann, D., Ertekin-Taner, N., Uitti, R. J., Wszolek, Z. K., Josephs, K. A., Parisi, J. E., Knopman, D. S., Petersen, R. C., Hodges, J. R., Piguet, O., Geier, E. G., Yokoyama, J. S., Rissman, R. A., Rogaeva, E., Keith, J., Zinman, L., Tartaglia, M. C., Cairns, N. J., Cruchaga, C., Ghetti, B., Kofler, J., Lopez, O. L., Beach, T. G., Arzberger, T., Herms, J., Honig, L. S., Vonsattel, J. P., Halliday, G. M., Kwok, J. B., White, C. L., Gearing, M., Glass, J., Rollinson, S., Pickering-Brown, S., Rohrer, J. D., Trojanowski, J. Q., Van Deerlin, V., Bigio, E. H., Troakes, C., Al-Sarraj, S., Asmann, Y., Miller, B. L., Graff-Radford, N. R., Boeve, B. F., Seeley, W. W., Mackenzie, I. R. A., van Swieten, J. C., Dickson, D. W., Biernacka, J. M. & Rademakers, R., Jun 1 2019, In : Acta neuropathologica. 137, 6, p. 879-899 21 p.

Research output: Contribution to journalArticle

13 Scopus citations

Genome-wide analysis of genetic loci associated with Alzheimer disease

Seshadri, S., Fitzpatrick, A. L., Ikram, M. A., DeStefano, A. L., Gudnason, V., Boada, M., Bis, J. C., Smith, A. V., Carassquillo, M. M., Lambert, J. C., Harold, D., Schrijvers, E. M. C., Ramirez-Lorca, R., Debette, S., Longstreth, W. T., Janssens, A. C. J. W., Pankratz, V. S., Dartigues, J. F., Hollingworth, P., Aspelund, T. & 43 others, Hernandez, I., Beiser, A., Kuller, L. H., Koudstaal, P. J., Dickson, D. W., Tzourio, C., Abraham, R., Antunez, C., Du, Y., Rotter, J. I., Aulchenko, Y. S., Harris, T. B., Petersen, R. C., Berr, C., Owen, M. J., Lopez-Arrieta, J., Varadarajan, B. N., Becker, J. T., Rivadeneira, F., Nalls, M. A., Graff-Radford, N. R., Campion, D., Auerbach, S., Rice, K., Hofman, A., Jonsson, P. V., Schmidt, H., Lathrop, M., Mosley, T. H., Au, R., Psaty, B. M., Uitterlinden, A. G., Farrer, L. A., Lumley, T., Ruiz, A., Williams, J., Amouyel, P., Younkin, S. G., Wolf, P. A., Launer, L. J., Lopez, O. L., Van Duijn, C. M. & Breteler, M. M. B., May 12 2010, In : JAMA - Journal of the American Medical Association. 303, 18, p. 1832-1840 9 p.

Research output: Contribution to journalArticle

813 Scopus citations

Genome-wide association analysis of hippocampal volume identifies enrichment of neurogenesis-related pathways

Alzheimer’s Disease Neuroimaging Initiative (ADNI), Dec 1 2019, In : Scientific reports. 9, 1, 14498.

Research output: Contribution to journalArticle

Open Access
2 Scopus citations

Genome-wide association interaction analysis for Alzheimer's disease

GERAD1 Consortium, Nov 1 2014, In : Neurobiology of aging. 35, 11, p. 2436-2443 8 p.

Research output: Contribution to journalArticle

38 Scopus citations

Genome-wide association study identifies four novel loci associated with Alzheimer’s endophenotypes and disease modifiers

Alzheimer’s Disease Neuroimaging Initiative (ADNI) & The Alzheimer Disease Genetic Consortium (ADGC), May 1 2017, In : Acta neuropathologica. 133, 5, p. 839-856 18 p.

Research output: Contribution to journalArticle

45 Scopus citations

Genome-wide association study of CSF biomarkers Aβ1-42, t-tau, and p-tau181p in the ADNI cohort

Kim, S., Swaminathan, S., Shen, L., Risacher, S. L., Nho, K., Foroud, T., Shaw, L. M., Trojanowski, J. Q., Potkin, S. G., Huentelman, M. J., Craig, D. W., Dechairo, B. M., Aisen, P. S., Petersen, R. C., Weiner, M. W. & Saykin, A. J., Jan 4 2011, In : Neurology. 76, 1, p. 69-79 11 p.

Research output: Contribution to journalArticle

137 Scopus citations

Genome-wide association study of prolactin levels in blood plasma and cerebrospinal fluid

for the Alzheimer's Disease Neuroimaging Initiative, Jun 29 2016, In : BMC genomics. 17, 436.

Research output: Contribution to journalArticle

2 Scopus citations

Genome-wide pathway analysis of memory impairment in the Alzheimer's Disease Neuroimaging Initiative (ADNI) cohort implicates gene candidates, canonical pathways, and networks

Ramanan, V. K., Kim, S., Holohan, K., Shen, L., Nho, K., Risacher, S. L., Foroud, T. M., Mukherjee, S., Crane, P. K., Aisen, P. S., Petersen, R. C., Weiner, M. W. & Saykin, A. J., Aug 6 2012, In : Brain Imaging and Behavior. 6, 4, p. 634-648 15 p.

Research output: Contribution to journalArticle

48 Scopus citations

Genome-wide screen identifies rs646776 near sortilin as a regulator of progranulin levels in human plasma

Carrasquillo, M. M., Nicholson, A. M., Finch, N., Gibbs, J. R., Baker, M., Rutherford, N. J., Hunter, T. A., Dejesus-Hernandez, M., Bisceglio, G. D., MacKenzie, I. R., Singleton, A., Cookson, M. R., Crook, J. E., Dillman, A., Hernandez, D., Petersen, R. C., Graff-Radford, N. R., Younkin, S. G. & Rademakers, R., Dec 10 2010, In : American journal of human genetics. 87, 6, p. 890-897 8 p.

Research output: Contribution to journalArticle

90 Scopus citations

Glaucoma and dementia: More than meets the eye?

Ward, M. E. & Petersen, R. C., Aug 1 2013, In : Annals of neurology. 74, 2, p. 155-157 3 p.

Research output: Contribution to journalEditorial

Glutathione S-transferase omega genes in Alzheimer and Parkinson disease risk, age-at-diagnosis and brain gene expression: An association study with mechanistic implications

Allen, M., Zou, F., Chai, H. S., Younkin, C. S., Miles, R., Nair, A. A., Crook, J. E., Pankratz, V. S., Carrasquillo, M. M., Rowley, C. N., Nguyen, T., Ma, L., Malphrus, K. G., Bisceglio, G., Ortolaza, A. I., Palusak, R., Middha, S., Maharjan, S., Georgescu, C., Schultz, D. & 14 others, Rakhshan, F., Kolbert, C. P., Jen, J., Sando, S. B., Aasly, J. O., Barcikowska, M., Uitti, R. J., Wszolek, Z. K., Ross, O. A., Petersen, R. C., Graff-Radford, N. R., Dickson, D. W., Younkin, S. G. & Ertekin-Taner, N., Apr 12 2012, In : Molecular neurodegeneration. 7, 1, 13.

Research output: Contribution to journalArticle

47 Scopus citations

Gray and white matter water diffusion in the syndromic variants of frontotemporal dementia

Whitwell, J. L., Avula, R., Senjem, M. L., Kantarci, K., Weigand, S. D., Samikoglu, A., Edmonson, H. A., Vemuri, P., Knopman, D. S., Boeve, B. F., Petersen, R. C., Josephs, K. A. & Jack, C. R., Apr 2010, In : Neurology. 74, 16, p. 1279-1287 9 p.

Research output: Contribution to journalArticle

168 Scopus citations

Guamanian neurodegenerative disease: Electrophysiologic findings

Ahlskog, J. E., Litchya, W. J., Petersen, R. C., Waring, S. C., Esteban-Santillan, C., Chen, K. M., Harper, C. M., Craig, U. K. & Kurland, L. T., Jun 15 1999, In : Journal of the neurological sciences. 166, 1, p. 28-35 8 p.

Research output: Contribution to journalArticle

6 Scopus citations

Guamanian neurodegenerative disease: Ultrastructural studies of skin

Ono, S., Waring, S. C., Kurland, L. L., Katrina-Craig, U. & Petersen, R. C., Feb 27 1997, In : Journal of the neurological sciences. 146, 1, p. 35-40 6 p.

Research output: Contribution to journalArticle

8 Scopus citations

Guamanian neurodegenerative disease: Investigation of the calcium metabolism/heavy meta1 hypothesis

Ahlskog, J. E., Waring, S. C., Kurland, L. T., Petersen, R. C., Moyer, T. P., Harmsen, W. S., Maraganore, D. M., O’brien, P. C., Esteban-Santillan, C. & Bush, V., Jul 1995, In : Neurology. 45, 7, p. 1340-1344 5 p.

Research output: Contribution to journalArticle

45 Scopus citations

Guamanian neurodegenerative disease: Are diabetes mellitus and altered humoral immunity clues to pathogenesis?

Ahlskog, J. E., Petersen, R. C., Waring, S. C., Esteban-Santillan, C., Craig, U. K., Maraganore, D. M., Lennon, V. A. & Kurland, L. T., May 1997, In : Neurology. 48, 5, p. 1356-1362 7 p.

Research output: Contribution to journalArticle

11 Scopus citations

GWAS of longitudinal amyloid accumulation on 18F-florbetapir PET in Alzheimer's disease implicates microglial activation gene IL1RAP

Ramanan, V. K., Risacher, S. L., Nho, K., Kim, S., Shen, L., McDonald, B. C., Yoder, K. K., Hutchins, G. D., West, J. D., Tallman, E. F., Gao, S., Foroud, T. M., Farlow, M. R., De Jager, P. L., Bennett, D. A., Aisen, P. S., Petersen, R. C., Jack, C. R., Toga, A. W., Green, R. C. & 3 others, Jagust, W. J., Weiner, M. W. & Saykin, A. J., Oct 1 2015, In : Brain. 138, 10, p. 3076-3088 13 p.

Research output: Contribution to journalArticle

59 Scopus citations

Head trauma and in vivo measures of amyloid and neurodegeneration in a population-based study

Mielke, M. M., Savica, R., Wiste, H. J., Weigand, S. D., Vemuri, P., Knopman, D. S., Lowe, V. J., Roberts, R. O., Machulda, M. M., Geda, Y. E., Petersen, R. C. & Jack, C. R., Jan 7 2014, In : Neurology. 82, 1, p. 70-76 7 p.

Research output: Contribution to journalArticle

32 Scopus citations

Heritability and genetic variance of dementia with Lewy bodies

for the International Parkinson's Disease Genomics Consortium, Jul 2019, In : Neurobiology of Disease. 127, p. 492-501 10 p.

Research output: Contribution to journalArticle

9 Scopus citations

Higher risk of progression to dementia in mild cognitive impairment cases who revert to normal

Roberts, R. O., Knopman, D. S., Mielke, M. M., Cha, R. H., Pankratz, V. S., Christianson, T. J. H., Geda, Y. E., Boeve, B. F., Ivnik, R. J., Tangalos, E. G., Rocca, W. A. & Petersen, R. C., Jan 28 2014, In : Neurology. 82, 4, p. 317-325 9 p.

Research output: Contribution to journalArticle

169 Scopus citations

High normal fasting blood glucose is associated with dementia in Chinese elderly

Mortimer, J. A., Borenstein, A. R., Ding, D., Decarli, C., Zhao, Q., Copenhaver, C., Guo, Q., Chu, S., Galasko, D., Salmon, D. P., Dai, Q., Wu, Y., Petersen, R. & Hong, Z., Nov 2010, In : Alzheimer's and Dementia. 6, 6, p. 440-447 8 p.

Research output: Contribution to journalArticle

16 Scopus citations

Hippocampal atrophy and apolipoprotein E genotype are independently associated with Alzheimer's disease

Jack, C. R., Petersen, R. C., Xu, Y. C., O'Brien, P. C., Waring, S. C., Tangalos, E. G., Smith, G. E., Ivnik, R. J., Thibodeau, S. N. & Kokmen, E., Mar 1 1998, In : Annals of neurology. 43, 3, p. 303-310 8 p.

Research output: Contribution to journalArticle

148 Scopus citations

Hippocampal atrophy correlates with clinical features of Alzheimer disease in African Americans

Sencakova, D., Graff-Radford, N. R., Willis, F. B., Lucas, J. A., Parfitt, F., Cha, R. H., O'Brien, P. C., Petersen, R. C. & Jack, C. R., Jan 1 2001, In : Archives of neurology. 58, 10, p. 1593-1597 5 p.

Research output: Contribution to journalArticle

Open Access
21 Scopus citations

Hippocampal atrophy rates and CSF biomarkers in elderly APOE2 normal subjects

Chiang, G. C., Insel, P. S., Tosun, D., Schuff, N., Truran-Sacrey, D., Raptentsetsang, S. T., Jack, C. R., Aisen, P. S., Petersen, R. C. & Weiner, M. W., Nov 30 2010, In : Neurology. 75, 22, p. 1976-1981 6 p.

Research output: Contribution to journalArticle

54 Scopus citations

Hippocampal transverse relaxation times in patients with Alzheimer disease

Campeau, N. G., Petersen, R. C., Felmlee, J. P., O'Brien, P. C. & Jack, C. R., Oct 1997, In : Radiology. 205, 1, p. 197-201 5 p.

Research output: Contribution to journalArticle

26 Scopus citations

Hippocampal Volume Is Associated with Memory but not Nonmemory Cognitive Performance in Patients with Mild Cognitive Impairment

Grundman, M., Jack, C. R., Petersen, R. C., Kim, H. T., Taylor, C., Datvian, M., Weiner, M. F., DeCarli, C., DeKosky, S. J., Van Dyck, C., Darvesh, S., Yaffe, K., Kaye, J., Ferris, S. H., Thomas, R. G. & Thal, L. J., Dec 1 2003, In : Journal of Molecular Neuroscience. 20, 3, p. 241-248 8 p.

Research output: Contribution to journalArticle

57 Scopus citations

Hippocampal volumes, proton magnetic resonance spectroscopy metabolites, and cerebrovascular disease in mild cognitive impairment subtypes

Kantarci, K., Petersen, R. C., Przybelski, S. A., Weigand, S. D., Shiung, M. M., Whitwell, J. L., Negash, S., Ivnik, R. J., Boeve, B. F., Knopman, D. S., Smith, G. E. & Jack, C. R., Dec 1 2008, In : Archives of neurology. 65, 12, p. 1621-1628 8 p.

Research output: Contribution to journalArticle

66 Scopus citations

Hippocampal volumes predict risk of dementia with Lewy bodies in mild cognitive impairment

Kantarci, K. M., Lesnick, T., Ferman, T. J., Przybelski, S. A., Boeve, B. F., Smith, G. E., Kremers, W. K., Knopman, D. S., Jack, C. R. J. & Petersen, R. C., Nov 29 2016, In : Neurology. 87, 22, p. 2317-2323 7 p.

Research output: Contribution to journalArticle

20 Scopus citations

HMGCR is a genetic modifier for risk, age of onset and MCI conversion to Alzheimer's disease in a three cohorts study

Leduc, V., De Beaumont, L., Théroux, L., Dea, D., Aisen, P., Petersen, R. C., Dufour, R. & Poirier, J., Jul 24 2015, In : Molecular Psychiatry. 20, 7, p. 867-873 7 p.

Research output: Contribution to journalArticle

27 Scopus citations

How can we best categorize cognitive impairment in nondemented older adults?

Sachdev, P. S., Ganguli, M. & Petersen, R. C., Aug 2010, In : American Journal of Geriatric Psychiatry. 18, 8, p. 657-661 5 p.

Research output: Contribution to journalEditorial

4 Scopus citations

How early can we diagnose Alzheimer disease (and is it sufficient)?

Petersen, R. C., Aug 28 2018, In : Neurology. 91, 9, p. 395-402 8 p.

Research output: Contribution to journalArticle

15 Scopus citations

Human state-dependent learning processes involving scopolamine

Petersen, R. C., Jan 1 1977, In : Federation Proceedings. 36, 3, p. No. 4083

Research output: Contribution to journalArticle

Human whole genome genotype and transcriptome data for Alzheimer's and other neurodegenerative diseases

Allen, M., Carrasquillo, M. M., Funk, C., Heavner, B. D., Zou, F., Younkin, C. S., Burgess, J. D., Chai, H. S., Crook, J., Eddy, J. A., Li, H., Logsdon, B., Peters, M. A., Dang, K. K., Wang, X., Serie, D., Wang, C., Nguyen, T., Lincoln, S., Malphrus, K. & 11 others, Bisceglio, G., Li, M., Golde, T. E., Mangravite, L. M., Asmann, Y., Price, N. D., Petersen, R. C., Graff Radford, N. R., Dickson, D. W., Younkin, S. G. & Taner, N., Oct 11 2016, In : Scientific data. 3, 160089.

Research output: Contribution to journalArticle

49 Scopus citations

Hypothetical model of dynamic biomarkers of the Alzheimer's pathological cascade

Jack, C. R., Knopman, D. S., Jagust, W. J., Shaw, L. M., Aisen, P. S., Weiner, M. W., Petersen, R. C. & Trojanowski, J. Q., Jan 2010, In : The Lancet Neurology. 9, 1, p. 119-128 10 p.

Research output: Contribution to journalComment/debate

2520 Scopus citations

Hypothyroidism and risk of mild cognitive impairment in elderly persons a population-based study

Parsaik, A. K., Singh, B., Roberts, R. O., Pankratz, S., Edwards, K. K., Geda, Y. E., Gharib, H., Boeve, B. F., Knopman, D. S. & Petersen, R. C., Feb 2014, In : JAMA neurology. 71, 2, p. 201-207 7 p.

Research output: Contribution to journalArticle

31 Scopus citations
204 Scopus citations
8 Scopus citations

Identification of evolutionarily conserved gene networks mediating neurodegenerative dementia

International Frontotemporal Dementia Genomics Consortium, Jan 1 2019, In : Nature Medicine. 25, 1, p. 152-164 13 p.

Research output: Contribution to journalArticle

10 Scopus citations

Identification of functional variants from whole-exome sequencing, combined with neuroimaging genetics

Nho, K., Corneveaux, J. J., Kim, S., Lin, H., Risacher, S. L., Shen, L., Swaminathan, S., Ramanan, V. K., Liu, Y., Foroud, T., Inlow, M. H., Siniard, A. L., Reiman, R. A., Aisen, P. S., Petersen, R. C., Green, R. C., Jack, C. R., Weiner, M. W., Baldwin, C. T., Lunetta, K. & 14 others, Farrer, L. A., Furney, S. J., Lovestone, S., Simmons, A., Mecocci, P., Vellas, B., Tsolaki, M., Kloszewska, I., Soininen, H., McDonald, B. C., Farlow, M. R., Ghetti, B., Huentelman, M. J. & Saykin, A. J., Jul 1 2013, In : Molecular Psychiatry. 18, 7, 1 p.

Research output: Contribution to journalComment/debate

6 Scopus citations

Identification of preclinical Alzheimer's disease by a profile of pathogenic proteins in neurally derived blood exosomes: A case-control study

Fiandaca, M. S., Kapogiannis, D., Mapstone, M., Boxer, A., Eitan, E., Schwartz, J. B., Abner, E. L., Petersen, R. C., Federoff, H. J., Miller, B. L. & Goetzl, E. J., Jun 1 2015, In : Alzheimer's and Dementia. 11, 6, p. 600-607.e1

Research output: Contribution to journalArticle

276 Scopus citations

Imagery and cued recall: Concreteness or context?

Petersen, R. C., May 1 1974, In : Journal of Experimental Psychology. 102, 5, p. 841-844 4 p.

Research output: Contribution to journalArticle

10 Scopus citations

Imaging and acetylcholinesterase inhibitor response in dementia with Lewy bodies

Graff-Radford, J., Boeve, B. F., Pedraza, O., Ferman, T. J., Przybelski, S., Lesnick, T. G., Vemuri, P., Senjem, M. L., Smith, G. E., Knopman, D. S., Lowe, V., Jack, C. R., Petersen, R. C. & Kantarci, K., Aug 2012, In : Brain. 135, 8, p. 2470-2477 8 p.

Research output: Contribution to journalArticle

40 Scopus citations
36 Scopus citations

Imaging Biomarkers of Alzheimer Disease in Multiple Sclerosis

Zeydan, B., Lowe, V. J., Reichard, R. R., Przybelski, S. A., Lesnick, T. G., Schwarz, C. G., Senjem, M. L., Gunter, J. L., Parisi, J. E., Machulda, M. M., Vemuri, P., Mielke, M. M., Knopman, D. S., Petersen, R. C., Jack, C. R., Kantarci, O. H. & Kantarci, K., Apr 1 2020, In : Annals of neurology. 87, 4, p. 556-567 12 p.

Research output: Contribution to journalArticle

Open Access
4 Scopus citations

Imaging correlates of pathology in corticobasal syndrome

Whitwell, J. L., Jack, C. R., Boeve, B. F., Parisi, J. E., Ahlskog, J. E., Drubach, D. A., Senjem, M. L., Knopman, D. S., Petersen, R. C., Dickson, D. W. & Josephs, K. A., Nov 23 2010, In : Neurology. 75, 21, p. 1879-1887 9 p.

Research output: Contribution to journalArticle

132 Scopus citations