• 127480 Citations
  • 160 Scopus h-Index
1974 …2020

Research output per year

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Research Output

2018

Statins and Brain Health: Alzheimer's Disease and Cerebrovascular Disease Biomarkers in Older Adults

Ramanan, V. K., Przybelski, S. A., Graff-Radford, J., Castillo, A. M., Lowe, V. J., Mielke, M. M., Roberts, R. O., Reid, R. I., Knopman, D. S., Jack, C. R., Petersen, R. C. & Vemuri, P., 2018, In : Journal of Alzheimer's Disease. 65, 4, p. 1345-1352 8 p.

Research output: Contribution to journalArticle

6 Scopus citations

Subjective cognitive decline and risk of MCI: The Mayo Clinic Study of Aging

van Harten, A. C., Mielke, M. M., Swenson-Dravis, D. M., Hagen, C. E., Edwards, K. K., Roberts, R. O., Geda, Y. E., Knopman, D. S. & Petersen, R. C., Jul 24 2018, In : Neurology. 91, 4, p. e300-e312

Research output: Contribution to journalArticle

27 Scopus citations

Tau-negative amnestic dementia masquerading as Alzheimer disease dementia

Botha, H., Mantyh, W. G., Graff-Radford, J., Machulda, M. M., Przybelski, S. A., Wiste, H. J., Senjem, M. L., Parisi, J. E., Petersen, R. C., Murray, M. E., Boeve, B. F., Lowe, V., Knopman, D. S., Jack, C. R. J. & Jones, D. T., Mar 13 2018, In : Neurology. 90, 11, p. e940-e946

Research output: Contribution to journalArticle

8 Scopus citations

Tau-PET imaging with [18F]AV-1451 in primary progressive apraxia of speech

Utianski, R. L., Whitwell, J. L., Schwarz, C. G., Senjem, M. L., Tosakulwong, N., Duffy, J. R., Clark, H. M., Machulda, M. M., Petersen, R. C., Jack, C. R., Lowe, V. J. & Josephs, K. A., Feb 2018, In : Cortex. 99, p. 358-374 17 p.

Research output: Contribution to journalArticle

17 Scopus citations
7 Scopus citations

TDP-43 and Alzheimer's Disease Pathologic Subtype in Non-Amnestic Alzheimer's Disease Dementia

Sahoo, A., Bejanin, A., Murray, M. E., Tosakulwong, N., Weigand, S. D., Serie, A. M., Senjem, M. L., MacHulda, M. M., Parisi, J. E., Boeve, B. F., Knopman, D. S., Petersen, R. C., Dickson, D. W., Whitwell, J. L. & Josephs, K. A., 2018, In : Journal of Alzheimer's Disease. 64, 4, p. 1227-1233 7 p.

Research output: Contribution to journalArticle

6 Scopus citations

The association between peripheral total IGF-1, IGFBP-3, and IGF-1/IGFBP-3 and functional and cognitive outcomes in the Mayo Clinic Study of Aging

Wennberg, A. M. V., Hagen, C. E., Machulda, M. M., Hollman, J. H., Roberts, R. O., Knopman, D. S., Petersen, R. C. & Mielke, M. M., Jun 2018, In : Neurobiology of aging. 66, p. 68-74 7 p.

Research output: Contribution to journalArticle

7 Scopus citations

The National Institute on Aging and the Alzheimer's Association Research Framework for Alzheimer's disease: Perspectives from the Research Roundtable

Knopman, D. S., Haeberlein, S. B., Carrillo, M. C., Hendrix, J. A., Kerchner, G., Margolin, R., Maruff, P., Miller, D. S., Tong, G., Tome, M. B., Murray, M. E., Nelson, P. T., Sano, M., Mattsson, N., Sultzer, D. L., Montine, T. J., Jack, C. R., Kolb, H., Petersen, R. C., Vemuri, P. & 8 others, Canniere, M. Z., Schneider, J. A., Resnick, S. M., Romano, G., van Harten, A. C., Wolk, D. A., Bain, L. J. & Siemers, E., Apr 2018, In : Alzheimer's and Dementia. 14, 4, p. 563-575 13 p.

Research output: Contribution to journalShort survey

34 Scopus citations

Trajectories of plasma IGF-1, IGFBP-3, and their ratio in the Mayo Clinic Study of Aging

Wennberg, A. M. V., Hagen, C. E., Petersen, R. C. & Mielke, M. M., Jun 2018, In : Experimental Gerontology. 106, p. 67-73 7 p.

Research output: Contribution to journalArticle

5 Scopus citations

Uncovering the heterogeneity and temporal complexity of neurodegenerative diseases with Subtype and Stage Inference

The Genetic FTD Initiative (GENFI) & The Alzheimer’S Disease Neuroimaging Initiative (ADNI), Dec 1 2018, In : Nature communications. 9, 1, 4273.

Research output: Contribution to journalArticle

32 Scopus citations

White matter reference region in PET studies of 11C-Pittsburgh compound B uptake: Effects of age and amyloid-β deposition

Lowe, V. J., Lundt, E. S., Senjem, M. L., Schwarz, C. G., Min, H. K., Przybelski, S. A., Kantarci, K., Knopman, D., Petersen, R. C. & Jack, C. R., Oct 1 2018, In : Journal of Nuclear Medicine. 59, 10, p. 1583-1589 7 p.

Research output: Contribution to journalArticle

9 Scopus citations
62 Scopus citations
2019
5 Scopus citations

A blood-based signature of cerebrospinal fluid Aβ 1–42 status

Alzheimer’s Disease Metabolomics Consortium & Alzheimer’s Disease Neuroimaging Initiative, Dec 1 2019, In : Scientific reports. 9, 1, 4163.

Research output: Contribution to journalArticle

Open Access
4 Scopus citations

A brief history of "Alzheimer disease": Multiple meanings separated by a common name

Knopman, D. S., Petersen, R. C. & Jack, C. R., May 28 2019, In : Neurology. 92, 22, p. 1053-1059 7 p.

Research output: Contribution to journalReview article

12 Scopus citations

A Comparison of Partial Volume Correction Techniques for Measuring Change in Serial Amyloid PET SUVR

Schwarz, C. G., Gunter, J. L., Lowe, V. J., Weigand, S., Vemuri, P., Senjem, M. L., Petersen, R. C., Knopman, D. S. & Jack, C. R., 2019, In : Journal of Alzheimer's Disease. 67, 1, p. 181-195 15 p.

Research output: Contribution to journalArticle

7 Scopus citations

A comprehensive screening of copy number variability in dementia with Lewy bodies

Kun-Rodrigues, C., Orme, T., Carmona, S., Hernandez, D. G., Ross, O. A., Eicher, J. D., Shepherd, C., Parkkinen, L., Darwent, L., Heckman, M. G., Scholz, S. W., Troncoso, J. C., Pletnikova, O., Dawson, T., Rosenthal, L., Ansorge, O., Clarimon, J., Lleo, A., Morenas-Rodriguez, E., Clark, L. & 48 others, Honig, L. S., Marder, K., Lemstra, A., Rogaeva, E., St. George-Hyslop, P., Londos, E., Zetterberg, H., Barber, I., Braae, A., Brown, K., Morgan, K., Troakes, C., Al-Sarraj, S., Lashley, T., Holton, J., Compta, Y., Van Deerlin, V., Serrano, G. E., Beach, T. G., Lesage, S., Galasko, D., Masliah, E., Santana, I., Pastor, P., Diez-Fairen, M., Aguilar, M., Tienari, P. J., Myllykangas, L., Oinas, M., Revesz, T., Lees, A., Boeve, B. F., Petersen, R. C., Ferman, T. J., Escott-Price, V., Graff-Radford, N., Cairns, N. J., Morris, J. C., Pickering-Brown, S., Mann, D., Halliday, G. M., Hardy, J., Trojanowski, J. Q., Dickson, D. W., Singleton, A., Stone, D. J., Guerreiro, R. & Bras, J., Mar 2019, In : Neurobiology of aging. 75, p. 223.e1-223.e10

Research output: Contribution to journalArticle

7 Scopus citations

A Joint Model for Predicting Structural and Functional Brain Health in Elderly Individuals

Varatharajah, Y., Saboo, K., Iyer, R., Przybelski, S., Schwarz, C., Petersen, R., Jack, C. & Vemuri, P., Nov 2019, Proceedings - 2019 IEEE International Conference on Bioinformatics and Biomedicine, BIBM 2019. Yoo, I., Bi, J. & Hu, X. T. (eds.). Institute of Electrical and Electronics Engineers Inc., p. 1657-1664 8 p. 8983291. (Proceedings - 2019 IEEE International Conference on Bioinformatics and Biomedicine, BIBM 2019).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

1 Scopus citations

Amyloid, Vascular, and Resilience Pathways Associated with Cognitive Aging

Vemuri, P., Lesnick, T. G., Knopman, D. S., Przybelski, S. A., Reid, R. I., Mielke, M. M., Graff-Radford, J., Lowe, V. J., Machulda, M. M., Petersen, R. C. & Jack, C. R., Dec 1 2019, In : Annals of neurology. 86, 6, p. 866-877 12 p.

Research output: Contribution to journalArticle

Open Access
2 Scopus citations
3 Scopus citations

A nonsynonymous mutation in PLCG2 reduces the risk of Alzheimer’s disease, dementia with Lewy bodies and frontotemporal dementia, and increases the likelihood of longevity

DESGESCO (Dementia Genetics Spanish Consortium), EADB (Alzheimer Disease European DNA biobank), EADB (Alzheimer Disease European DNA biobank), IFGC (International FTD-Genomics Consortium), IPDGC (The International Parkinson Disease Genomics Consortium), IPDGC (The International Parkinson Disease Genomics Consortium), RiMod-FTD (Risk and Modifying factors in Fronto-Temporal Dementia), Netherlands Brain Bank (NBB) & The GIFT (Genetic Investigation in Frontotemporal Dementia and Alzheimer’s Disease) Study Group, Aug 1 2019, In : Acta neuropathologica. 138, 2, p. 237-250 14 p.

Research output: Contribution to journalArticle

Open Access
15 Scopus citations

A Novel Joint Brain Network Analysis Using Longitudinal Alzheimer’s Disease Data

The Alzheimer’s Disease Neuroimaging Initiative, Dec 1 2019, In : Scientific reports. 9, 1, 19589.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations

Antemortem volume loss mirrors TDP-43 staging in older adults with non-frontotemporal lobar degeneration

Bejanin, A., Murray, M. E., Martin, P., Botha, H., Tosakulwong, N., Schwarz, C. G., Senjem, M. L., Chételat, G., Kantarci, K., Jack, C. R., Boeve, B. F., Knopman, D. S., Petersen, R. C., Giannini, C., Parisi, J. E., Dickson, D. W., Whitwell, J. L. & Josephs, K. A., Nov 1 2019, In : Brain. 142, 11, p. 3621-3635 15 p.

Research output: Contribution to journalArticle

5 Scopus citations

Association Between Critical Care Admissions and Cognitive Trajectories in Older Adults∗

Schulte, P. J., Warner, D. O., Martin, D. P., Deljou, A., Mielke, M. M., Knopman, D. S., Petersen, R. C., Weingarten, T. N., Warner, M. A., Rabinstein, A. A., Hanson, A. C., Schroeder, D. R. & Sprung, J., Aug 1 2019, In : Critical care medicine. 47, 8, p. 1116-1124 9 p.

Research output: Contribution to journalArticle

2 Scopus citations
Open Access
2 Scopus citations

Association of Bilateral Salpingo-Oophorectomy before Menopause Onset with Medial Temporal Lobe Neurodegeneration

Zeydan, B., Tosakulwong, N., Schwarz, C. G., Senjem, M. L., Gunter, J. L., Reid, R. I., Gazzuola Rocca, L., Lesnick, T. G., Smith, C. Y., Bailey, K. R., Lowe, V. J., Roberts, R. O., Jack, C. R., Petersen, R. C., Miller, V. M., Mielke, M. M., Rocca, W. A. & Kantarci, K., Jan 2019, In : JAMA neurology. 76, 1, p. 95-100 6 p.

Research output: Contribution to journalArticle

8 Scopus citations

Association of Cerebrospinal Fluid Neurofilament Light Protein with Risk of Mild Cognitive Impairment among Individuals Without Cognitive Impairment

Kern, S., Syrjanen, J. A., Blennow, K., Zetterberg, H., Skoog, I., Waern, M., Hagen, C. E., Van Harten, A. C., Knopman, D. S., Jack, C. R., Petersen, R. C. & Mielke, M. M., Feb 2019, In : JAMA neurology. 76, 2, p. 187-193 7 p.

Research output: Contribution to journalArticle

11 Scopus citations
Open Access

Association of mapt subhaplotypes with risk of progressive supranuclear palsy and severity of tau pathology

Heckman, M. G., Brennan, R. R., Labbé, C., Soto, A. I., Koga, S., Deture, M. A., Murray, M. E., Petersen, R. C., Boeve, B. F., Van Gerpen, J. A., Uitti, R. J., Wszolek, Z. K., Rademakers, R., Dickson, D. W. & Ross, O. A., Jun 2019, In : JAMA neurology. 76, 6, p. 710-717 8 p.

Research output: Contribution to journalArticle

9 Scopus citations

Association of non-exercise physical activity in mid- and late-life with cognitive trajectories and the impact of APOE ε4 genotype status: the Mayo Clinic Study of Aging

Krell-Roesch, J., Syrjanen, J. A., Vassilaki, M., Barisch-Fritz, B., Trautwein, S., Boes, K., Woll, A., Kremers, W. K., Machulda, M. M., Mielke, M. M., Knopman, D. S., Petersen, R. C. & Geda, Y. E., Dec 1 2019, In : European Journal of Ageing. 16, 4, p. 491-502 12 p.

Research output: Contribution to journalArticle

Open Access
24 Scopus citations

Author Correction: Genetic meta-analysis of diagnosed Alzheimer’s disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing (Nature Genetics, (2019), 51, 3, (414-430), 10.1038/s41588-019-0358-2)

Alzheimer Disease Genetics Consortium (ADGC), The European Alzheimer’s Disease Initiative (EADI), Cohorts for Heart and Aging Research in Genomic Epidemiology Consortium (CHARGE) & Genetic and Environmental Risk in AD/Defining Genetic, Polygenic and Environmental Risk for Alzheimer’s Disease Consortium (GERAD/PERADES), Sep 1 2019, In : Nature Genetics. 51, 9, p. 1423-1424 2 p.

Research output: Contribution to journalComment/debate

Open Access
3 Scopus citations

Automated and manual hippocampal segmentation techniques: Comparison of results, reproducibility and clinical applicability

Hurtz, S., Chow, N., Watson, A. E., Somme, J. H., Goukasian, N., Hwang, K. S., Morra, J., Elashoff, D., Gao, S., Petersen, R. C., Aisen, P. S., Thompson, P. M. & Apostolova, L. G., 2019, In : NeuroImage: Clinical. 21, 101574.

Research output: Contribution to journalArticle

2 Scopus citations
5 Scopus citations
6 Scopus citations

Cardiometabolic Health and Longitudinal Progression of White Matter Hyperintensity: The Mayo Clinic Study of Aging

Scharf, E. L., Graff-Radford, J., Przybelski, S. A., Lesnick, T. G., Mielke, M. M., Knopman, D. S., Preboske, G. M., Schwarz, C. G., Senjem, M. L., Gunter, J. L., Machulda, M., Kantarci, K., Petersen, R. C., Jack, C. R. & Vemuri, P., Nov 1 2019, In : Stroke. 50, 11, p. 3037-3044 8 p.

Research output: Contribution to journalArticle

1 Scopus citations

Cerebral microbleeds: Prevalence and relationship to amyloid burden

Graff-Radford, J., Botha, H., Rabinstein, A. A., Gunter, J. L., Przybelski, S. A., Lesnick, T., Huston, J., Flemming, K. D., Preboske, G. M., Senjem, M. L., Brown, R. D., Mielke, M. M., Roberts, R. O., Lowe, V. J., Knopman, D. S., Petersen, R. C., Kremers, W., Vemuri, P., Jack, C. R. & Kantarci, K., Jan 15 2019, In : Neurology. 92, 3, p. E253-E262

Research output: Contribution to journalArticle

9 Scopus citations

Cerebrospinal fluid dynamics disorders: Relationship to Alzheimer biomarkers and cognition

Graff-Radford, J., Gunter, J. L., Jones, D. T., Przybelski, S. A., Schwarz, C. G., Huston, J., Lowe, V., Elder, B. D., MacHulda, M. M., Gunter, N. B., Petersen, R. C., Kantarci, K., Vemuri, P., Mielke, M. M., Knopman, D. S., Graff-Radford, N. R. & Jack, C. R., Dec 10 2019, In : Neurology. 93, 24, p. E2237-E2246

Research output: Contribution to journalArticle

Cognitive function after surgery with regional or general anesthesia: A population-based study

Sprung, J., Schulte, P. J., Knopman, D. S., Mielke, M. M., Petersen, R. C., Weingarten, T. N., Martin, D. P., Hanson, A. C., Schroeder, D. R. & Warner, D. O., Oct 2019, In : Alzheimer's and Dementia. 15, 10, p. 1243-1252 10 p.

Research output: Contribution to journalArticle

1 Scopus citations
1 Scopus citations
2 Scopus citations

Comparison of variables associated with cerebrospinal fluid neurofilament, total-tau, and neurogranin

Mielke, M. M., Syrjanen, J. A., Blennow, K., Zetterberg, H., Skoog, I., Vemuri, P., Machulda, M. M., Graff-Radford, J., Knopman, D. S., Jack, C. R., Petersen, R. C. & Kern, S., Nov 2019, In : Alzheimer's and Dementia. 15, 11, p. 1437-1447 11 p.

Research output: Contribution to journalArticle

1 Scopus citations

Cortical β-amyloid burden, neuropsychiatric symptoms, and cognitive status: the Mayo Clinic Study of Aging

Krell-Roesch, J., Vassilaki, M., Mielke, M. M., Kremers, W. K., Lowe, V. J., Vemuri, P., Machulda, M. M., Christianson, T. J., Syrjanen, J. A., Stokin, G. B., Butler, L. M., Traber, M., Jack, C. R., Knopman, D. S., Roberts, R. O., Petersen, R. C. & Geda, Y. E., Dec 1 2019, In : Translational psychiatry. 9, 1, 123.

Research output: Contribution to journalArticle

Open Access
8 Scopus citations

Cross-sectional associations of tau-PET signal with cognition in cognitively unimpaired adults

Lowe, V. J., Bruinsma, T. J., Wiste, H. J., Min, H. K., Weigand, S. D., Fang, P., Senjem, M. L., Therneau, T. M., Boeve, B. F., Josephs, K. A., Pandey, M. K., Murray, M. E., Kantarci, K., Jones, D. T., Vemuri, P., Graff-Radford, J., Schwarz, C. G., Machulda, M. M., Mielke, M. M., Roberts, R. O. & 3 others, Knopman, D. S., Petersen, R. C. & Jack, C. R., Jul 2 2019, In : Neurology. 93, 1, p. E29-E39

Research output: Contribution to journalArticle

7 Scopus citations

CSF1R mutation presenting as dementia with Lewy bodies

Sharma, R., Graff-Radford, J., Rademakers, R. V., Boeve, B. F., Petersen, R. C. & Jones, D. T., Jan 1 2019, In : Neurocase.

Research output: Contribution to journalArticle

2 Scopus citations

Deep Learning Prediction of Mild Cognitive Impairment using Electronic Health Records

Fouladvand, S., Mielke, M. M., Vassilaki, M., St Sauver, J., Petersen, R. C. & Sohn, S., Nov 2019, Proceedings - 2019 IEEE International Conference on Bioinformatics and Biomedicine, BIBM 2019. Yoo, I., Bi, J. & Hu, X. T. (eds.). Institute of Electrical and Electronics Engineers Inc., p. 799-806 8 p. 8982955. (Proceedings - 2019 IEEE International Conference on Bioinformatics and Biomedicine, BIBM 2019).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Distinct cytokine profiles in human brains resilient to Alzheimer's pathology

Barroeta-Espar, I., Weinstock, L. D., Perez-Nievas, B. G., Meltzer, A. C., Siao Tick Chong, M., Amaral, A. C., Murray, M. E., Moulder, K. L., Morris, J. C., Cairns, N. J., Parisi, J. E., Lowe, V. J., Petersen, R. C., Kofler, J., Ikonomovic, M. D., López, O., Klunk, W. E., Mayeux, R. P., Frosch, M. P., Wood, L. B. & 1 others, Gomez-Isla, T., Jan 2019, In : Neurobiology of Disease. 121, p. 327-337 11 p.

Research output: Contribution to journalArticle

16 Scopus citations
21 Scopus citations
1 Scopus citations