Richard M Weinshilboum, MD

Professor

  • 26570 Citations
  • 83 h-Index
1968 …2020
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Pharmacogenetics Medicine & Life Sciences
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Projects 1979 2020

thiopurine methyltransferase
Histamine N-Methyltransferase
Enzymes
Pharmaceutical Preparations
Methylation
Genes
Engines
User interfaces
Learning systems
Computational methods
Pharmacogenetics
Adjuvant Chemotherapy
Breast Neoplasms
Genome-Wide Association Study
gemcitabine
Pharmacogenetics
Cytarabine
Acute Myeloid Leukemia
Cell Line
Genetic Association Studies

Research Output 1968 2019

docetaxel
Estrogen Receptors
Single Nucleotide Polymorphism
Estrogens
Breast Neoplasms

Altered serotonergic circuitry in SSRI-resistant major depressive disorder patient-derived neurons

Vadodaria, K. C., Ji, Y., Skime, M., Paquola, A. C., Nelson, T. J., Hall-Flavin, D., Heard, K. J., Fredlender, C., Deng, Y., Elkins, J., Dani, K., Le, A. T., Marchetto, M. C., Weinshilboum, R. M. & Gage, F. H., Jan 1 2019, In : Molecular Psychiatry.

Research output: Contribution to journalArticle

Major Depressive Disorder
Serotonin Uptake Inhibitors
Serotonergic Neurons
Neurons
Induced Pluripotent Stem Cells

Anastrozole Aromatase Inhibitor Plasma Drug Concentration Genome-Wide Association Study: Functional Epistatic Interaction Between SLC38A7 and ALPPL2

Dudenkov, T. M., Liu, D., Cairns, J., Devarajan, S., Zhuang, Y., Ingle, J. N., Buzdar, A. U., Robson, M. E., Kubo, M., Batzler, A., Barman, P., Jenkins, G. D., Carlson, E. E., Goetz, M. P., Northfelt, D. W., Moreno Aspitia, A., Desta, Z., Reid, J. M., Kalari, K. R., Wang, L. M. & 1 othersWeinshilboum, R. M., Jan 1 2019, In : Clinical pharmacology and therapeutics.

Research output: Contribution to journalArticle

Open Access
Aromatase Inhibitors
Genome-Wide Association Study
Single Nucleotide Polymorphism
Pharmaceutical Preparations
Breast Neoplasms

Clopidogrel Pharmacogenetics

Pereira, N. L., Rihal, C. S., So, D. Y. F., Rosenberg, Y., Lennon, R. J., Mathew, V., Goodman, S. G., Weinshilboum, R. M., Wang, L. M., Baudhuin, L. M., Lerman, A., Hasan, A., Iturriaga, E., Fu, Y. P., Geller, N., Bailey, K. R. & Farkouh, M. E., Apr 1 2019, In : Circulation. Cardiovascular interventions. 12, 4, p. e007811

Research output: Contribution to journalArticle

clopidogrel
Pharmacogenetics
Percutaneous Coronary Intervention
Alleles
Drug Labeling

Pharmacogenomic next-generation DNA sequencing: Lessons from the identification and functional characterization of variants of unknown significance in CYP2C9 and CYP2C19

Devarajan, S., Moon, I., Ho, M. F., Larson, N., Neavin, D. R., Moyer, A. M., Black, J. L., Bielinski, S. J., Scherer, S. E., Wang, L. M., Weinshilboum, R. M. & Reid, J. M., Apr 1 2019, In : Drug Metabolism and Disposition. 47, 4, p. 425-435 11 p.

Research output: Contribution to journalArticle

Pharmacogenetics
DNA Sequence Analysis
Cytochrome P-450 Enzyme System
Oxidoreductases
Proteins