Richard M Weinshilboum, MD

  • 28270 Citations
  • 85 Scopus h-Index
1968 …2020

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Article
2020

Acylcarnitine metabolomic profiles inform clinically-defined major depressive phenotypes

The Mood Disorders Precision Medicine Consortium (MDPMC), Mar 1 2020, In : Journal of Affective Disorders. 264, p. 90-97 8 p.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations

Anastrozole has an association between degree of estrogen suppression and outcomes in early breast cancer and is a ligand for estrogen receptor

Ingle, J. N., Cairns, J., Suman, V. J., Shepherd, L. E., Fasching, P. A., Hoskin, T. L., Singh, R. J., Desta, Z., Kalari, K. R., Ellis, M. J., Goss, P. E., Chen, B. E., Volz, B., Barman, P., Carlson, E. E., Haddad, T., Goetz, M. P., Goodnature, B., Cuellar, M. E., Walters, M. A. & 4 others, Correia, C., Kaufmann, S. H., Weinshilboum, R. M. & Wang, L., Jun 15 2020, In : Clinical Cancer Research. 26, 12, p. 2986-2996 11 p.

Research output: Contribution to journalArticle

Open Access

Cohort Profile: The Right Drug, Right Dose, Right Time: Using Genomic Data to Individualize Treatment Protocol (RIGHT Protocol)

Bielinski, S. J., St Sauver, J. L., Olson, J. E., Larson, N. B., Black, J. L., Scherer, S. E., Bernard, M. E., Boerwinkle, E., Borah, B. J., Caraballo, P. J., Curry, T. B., Doddapaneni, H. V., Formea, C. M., Freimuth, R. R., Gibbs, R. A., Giri, J., Hathcock, M. A., Hu, J., Jacobson, D. J., Jones, L. A. & 28 others, Kalla, S., Koep, T. H., Korchina, V., Kovar, C. L., Lee, S., Liu, H., Matey, E. T., McGree, M. E., McAllister, T. M., Moyer, A. M., Muzny, D. M., Nicholson, W. T., Oyen, L. J., Qin, X., Raj, R., Roger, V. L., Rohrer Vitek, C. R., Ross, J. L., Sharp, R. R., Takahashi, P. Y., Venner, E., Walker, K., Wang, L., Wang, Q., Wright, J. A., Wu, T. J., Wang, L. & Weinshilboum, R. M., Feb 1 2020, In : International journal of epidemiology. 49, 1, p. 23-24K

Research output: Contribution to journalArticle

5 Scopus citations
Open Access

CYP2C9 and CYP2C19: Deep Mutational Scanning and Functional Characterization of Genomic Missense Variants

Zhang, L., Sarangi, V., Moon, I., Yu, J., Liu, D., Devarajan, S., Reid, J. M., Kalari, K. R., Wang, L. & Weinshilboum, R., Jul 1 2020, In : Clinical and translational science. 13, 4, p. 727-742 16 p.

Research output: Contribution to journalArticle

Open Access

Knowledge-guided analysis of "omics" data using the KnowEnG cloud platform

Blatti, C., Emad, A., Berry, M. J., Gatzke, L., Epstein, M., Lanier, D., Rizal, P., Ge, J., Liao, X., Sobh, O., Lambert, M., Post, C. S., Xiao, J., Groves, P., Epstein, A. T., Chen, X., Srinivasan, S., Lehnert, E., Kalari, K. R., Wang, L. & 8 others, Weinshilboum, R. M., Song, J. S., Jongeneel, C. V., Han, J., Ravaioli, U., Sobh, N., Bushell, C. B. & Sinha, S., 2020, In : PLoS biology. 18, 1, e3000583.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations

Next-Generation Sequencing of CYP2C19 in Stent Thrombosis: Implications for Clopidogrel Pharmacogenomics

Morales-Rosado, J. A., Goel, K., Zhang, L., Åkerblom, A., Baheti, S., Black, J. L., Eriksson, N., Wallentin, L., James, S., Storey, R. F., Goodman, S. G., Jenkins, G. D., Eckloff, B. W., Bielinski, S. J., Sicotte, H., Johnson, S., Roger, V. L., Wang, L., Weinshilboum, R. M., Klee, E. W. & 2 others, Rihal, C. S. & Pereira, N. L., 2020, (Accepted/In press) In : Cardiovascular Drugs and Therapy.

Research output: Contribution to journalArticle

Regulation of sister chromatid cohesion by nuclear PD-L1

Yu, J., Qin, B., Moyer, A. M., Nowsheen, S., Tu, X., Dong, H., Boughey, J. C., Goetz, M. P., Weinshilboum, R., Lou, Z. & Wang, L., 2020, (Accepted/In press) In : Cell Research.

Research output: Contribution to journalArticle

Open Access
2019
2 Scopus citations

Altered serotonergic circuitry in SSRI-resistant major depressive disorder patient-derived neurons

Vadodaria, K. C., Ji, Y., Skime, M., Paquola, A. C., Nelson, T. J., Hall-Flavin, D., Heard, K. J., Fredlender, C., Deng, Y., Elkins, J., Dani, K., Le, A. T., Marchetto, M. C., Weinshilboum, R. M. & Gage, F. H., Jan 1 2019, In : Molecular Psychiatry.

Research output: Contribution to journalArticle

7 Scopus citations

Anastrozole Aromatase Inhibitor Plasma Drug Concentration Genome-Wide Association Study: Functional Epistatic Interaction Between SLC38A7 and ALPPL2

Dudenkov, T. M., Liu, D., Cairns, J., Devarajan, S., Zhuang, Y., Ingle, J. N., Buzdar, A. U., Robson, M. E., Kubo, M., Batzler, A., Barman, P., Jenkins, G. D., Carlson, E. E., Goetz, M. P., Northfelt, D. W., Moreno-Aspitia, A., Desta, Z., Reid, J. M., Kalari, K. R., Wang, L. & 1 others, Weinshilboum, R. M., Jul 2019, In : Clinical pharmacology and therapeutics. 106, 1, p. 219-227 9 p.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations

Clopidogrel pharmacogenetics state-of-the-art review and the TAILOR-PCI study

Pereira, N. L., Rihal, C. S., So, D. Y. F., Rosenberg, Y., Lennon, R. J., Mathew, V., Goodman, S. G., Weinshilboum, R. M., Wang, L., Baudhuin, L. M., Lerman, A., Hasan, A., Iturriaga, E., Fu, Y. P., Geller, N., Bailey, K. & Farkouh, M. E., Apr 1 2019, In : Circulation: Cardiovascular Interventions. 12, 4

Research output: Contribution to journalArticle

11 Scopus citations

Comparison of 99mTc-sestamibi molecular breast imaging and breast MRI in patients with invasive breast cancer receiving neoadjuvant chemotherapy

Hunt, K. N., Conners, A. L., Goetz, M. P., O’Connor, M. K., Suman, V., Kalari, K., Weinshilboum, R., Wang, L., Carter, J., McLaughlin, S. A., Aspitia, A. M., Gray, R. J., Northfelt, D. & Boughey, J. C., Jan 1 2019, In : American Journal of Roentgenology. 213, 4, p. 932-943 12 p.

Research output: Contribution to journalArticle

2 Scopus citations

Deep sequencing across germline genome-wide association study signals relating to breast cancer events in women receiving aromatase inhibitors for adjuvant therapy of early breast cancer

Ingle, J. N., Kalari, K. R., Momozawa, Y., Kubo, M., Furukawa, Y., Shepherd, L. E., Ellis, M. J., Goss, P. E., Barman, P., Carlson, E. E., Sinnwell, J. P., Tang, X., Goetz, M. P., Chen, B. E., Cairns, J., Weinshilboum, R. M. & Wang, L., Oct 1 2019, In : Pharmacogenetics and genomics. 29, 8, p. 183-191 9 p.

Research output: Contribution to journalArticle

Open Access
2 Scopus citations

Genetic predictors of chemotherapy-related amenorrhea in women with breast cancer

Ruddy, K. J., Schaid, D. J., Partridge, A. H., Larson, N. B., Batzler, A., Häberle, L., Dittrich, R., Widschwendter, P., Fink, V., Bauer, E., Schwitulla, J., Rübner, M., Ekici, A. B., Aivazova-Fuchs, V., Stewart, E. A., Beckmann, M. W., Ginsburg, E., Wang, L., Weinshilboum, R. M., Couch, F. J. & 4 others, Janni, W., Rack, B., Vachon, C. & Fasching, P. A., Jan 1 2019, (Accepted/In press) In : Fertility and Sterility.

Research output: Contribution to journalArticle

Open Access
3 Scopus citations

Metabolomic signature of exposure and response to citalopram/escitalopram in depressed outpatients

Bhattacharyya, S., Ahmed, A. T., Arnold, M., Liu, D., Luo, C., Zhu, H., Mahmoudiandehkordi, S., Neavin, D., Louie, G., Dunlop, B. W., Frye, M. A., Wang, L., Weinshilboum, R. M., Krishnan, R. R., Rush, A. J. & Kaddurah-Daouk, R., Dec 1 2019, In : Translational psychiatry. 9, 1, 173.

Research output: Contribution to journalArticle

Open Access
4 Scopus citations
4 Scopus citations

Pharmacogenomics-Driven Prediction of Antidepressant Treatment Outcomes: A Machine-Learning Approach With Multi-trial Replication

Athreya, A. P., Neavin, D., Carrillo-Roa, T., Skime, M., Biernacka, J., Frye, M. A., Rush, A. J., Wang, L., Binder, E. B., Iyer, R. K., Weinshilboum, R. M. & Bobo, W. V., Oct 1 2019, In : Clinical pharmacology and therapeutics. 106, 4, p. 855-865 11 p.

Research output: Contribution to journalArticle

14 Scopus citations
4 Scopus citations

Pilot Study of Metabolomic Clusters as State Markers of Major Depression and Outcomes to CBT Treatment

Bhattacharyya, S., Dunlop, B. W., Mahmoudiandehkordi, S., Ahmed, A. T., Louie, G., Frye, M. A., Weinshilboum, R. M., Krishnan, R. R., Rush, A. J., Mayberg, H. S., Craighead, W. E. & Kaddurah-Daouk, R., Sep 12 2019, In : Frontiers in Neuroscience. 13, 926.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations

Serotonin-induced hyperactivity in SSRI-resistant major depressive disorder patient-derived neurons

Vadodaria, K. C., Ji, Y., Skime, M., Paquola, A., Nelson, T. J., Hall-Flavin, D., Fredlender, C., Heard, K. J., Deng, Y., Le, A. T., Dave, S., Fung, L., Li, X., Marchetto, M. C., Weinshilboum, R. M. & Gage, F. H., Jan 1 2019, In : Molecular Psychiatry.

Research output: Contribution to journalArticle

7 Scopus citations
Open Access
1 Scopus citations

Targeted Treatment of Individuals With Psychosis Carrying a Copy Number Variant Containing a Genomic Triplication of the Glycine Decarboxylase Gene

Bodkin, J. A., Coleman, M. J., Godfrey, L. J., Carvalho, C. M. B., Morgan, C. J., Suckow, R. F., Anderson, T., Öngür, D., Kaufman, M. J., Lewandowski, K. E., Siegel, A. J., Waldstreicher, E., Grochowski, C. M., Javitt, D. C., Rujescu, D., Hebbring, S., Weinshilboum, R., Rodriguez, S. B., Kirchhoff, C., Visscher, T. & 11 others, Vuckovic, A., Fialkowski, A., McCarthy, S., Malhotra, D., Sebat, J., Goff, D. C., Hudson, J. I., Lupski, J. R., Coyle, J. T., Rudolph, U. & Levy, D. L., Oct 1 2019, In : Biological psychiatry. 86, 7, p. 523-535 13 p.

Research output: Contribution to journalArticle

6 Scopus citations

The association of obesity and coronary artery disease genes with response to SSRIs treatment in major depression

Amare, A. T., Schubert, K. O., Tekola-Ayele, F., Hsu, Y. H., Sangkuhl, K., Jenkins, G., Whaley, R. M., Barman, P., Batzler, A., Altman, R. B., Arolt, V., Brockmöller, J., Chen, C. H., Domschke, K., Hall-Flavin, D. K., Hong, C. J., Illi, A., Ji, Y., Kampman, O., Kinoshita, T. & 17 others, Leinonen, E., Liou, Y. J., Mushiroda, T., Nonen, S., Skime, M. K., Wang, L. M., Kato, M., Liu, Y. L., Praphanphoj, V., Stingl, J. C., Bobo, W. V., Tsai, S. J., Kubo, M., Klein, T. E., Weinshilboum, R. M., Biernacka, J. M. & Baune, B. T., Jan 1 2019, (Accepted/In press) In : Journal of Neural Transmission.

Research output: Contribution to journalArticle

3 Scopus citations

The lncRNA MIR2052HG regulates ERα levels and aromatase inhibitor resistance through LMTK3 by recruiting EGR1

Cairns, J., Ingle, J. N., Kalari, K. R., Shepherd, L. E., Kubo, M., Goetz, M. P., Weinshilboum, R. M. & Wang, L. M., Apr 3 2019, In : Breast Cancer Research. 21, 1, 47.

Research output: Contribution to journalArticle

Open Access
8 Scopus citations
2018

A prospective genome-wide study of prostate cancer metastases reveals association of wnt pathway activation and increased cell cycle proliferation with primary resistance to abiraterone acetate-prednisone

Wang, L., Dehm, S. M., Hillman, D. W., Sicotte, H., Tan, W., Gormley, M., Bhargava, V., Jimenez, R., Xie, F., Yin, P., Qin, S., Quevedo, F., Costello, B. A., Pitot, H. C., Ho, T., Bryce, A. H., Ye, Z., Li, Y., Eiken, P., Vedell, P. T. & 16 others, Barman, P., McMenomy, B. P., Atwell, T. D., Carlson, R. E., Ellingson, M., Eckloff, B. W., Qin, R., Ou, F., Hart, S. N., Huang, H., Jen, J., Wieben, E. D., Kalari, K. R., Weinshilboum, R. M., Wang, L. & Kohli, M., Feb 1 2018, In : Annals of Oncology. 29, 2, p. 352-360 9 p.

Research output: Contribution to journalArticle

21 Scopus citations

Association of the polygenic scores for personality traits and response to selective serotonin reuptake inhibitors in patients with major depressive disorder

Amare, A. T., Schubert, K. O., Tekola-Ayele, F., Hsu, Y. H., Sangkuhl, K., Jenkins, G., Whaley, R. M., Barman, P., Batzler, A., Altman, R. B., Arolt, V., Brockmöller, J., Chen, C. H., Domschke, K., Hall-Flavin, D. K., Hong, C. J., Illi, A., Ji, Y., Kampman, O., Kinoshita, T. & 17 others, Leinonen, E., Liou, Y. J., Mushiroda, T., Nonen, S., Skime, M. K., Wang, L. M., Kato, M., Liu, Y. L., Praphanphoj, V., Stingl, J. C., Bobo, W. V., Tsai, S. J., Kubo, M., Klein, T. E., Weinshilboum, R. M., Biernacka, J. M. & Baune, B. T., Mar 6 2018, In : Frontiers in Psychiatry. 9, MAR, 65.

Research output: Contribution to journalArticle

8 Scopus citations

Augmentation of physician assessments with multi-omics enhances predictability of drug response: A case study of major depressive disorder

Athreya, A., Iyer, R., Neavin, D., Wang, L. M., Weinshilboum, R. M., Kaddurah-Daouk, R., Rush, J., Frye, M. A. & Bobo, W. V., Aug 1 2018, In : IEEE Computational Intelligence Magazine. 13, 3, p. 20-31 12 p., 8416980.

Research output: Contribution to journalArticle

10 Scopus citations

Benefits of and Barriers to Pharmacogenomics-Guided Treatment for Major Depressive Disorder

Ahmed, A. T., Weinshilboum, R. M. & Frye, M. A., Jan 1 2018, (Accepted/In press) In : Clinical Pharmacology and Therapeutics.

Research output: Contribution to journalArticle

6 Scopus citations

Beta-defensin 1, aryl hydrocarbon receptor and plasma kynurenine in major depressive disorder: Metabolomics-informed genomics

Liu, D., Ray, B., Neavin, D. R., Zhang, J., Athreya, A. P., Biernacka, J. M., Bobo, W. V., Hall-Flavin, D. K., Skime, M. K., Zhu, H., Jenkins, G. D., Batzler, A., Kalari, K. R., Boakye-Agyeman, F., Matson, W. R., Bhasin, S. S., Mushiroda, T., Nakamura, Y., Kubo, M., Iyer, R. K. & 4 others, Wang, L. M., Frye, M. A., Kaddurah-Daouk, R. & Weinshilboum, R. M., Dec 1 2018, In : Translational Psychiatry. 8, 1, 56.

Research output: Contribution to journalArticle

15 Scopus citations

BRCA1/2 Mutations and bevacizumab in the neoadjuvant treatment of breast cancer: Response and prognosis results in patients with triple-negative breast cancer From the geparquinto study

Fasching, P. A., Loibl, S., Hu, C., Hart, S. N., Shimelis, H., Moore, R., Schem, C., Tesch, H., Untch, M., Hilfrich, J., Rezai, M., Gerber, B., Costa, S. D., Blohmer, J. U., Fehm, T., Huober, J., Liedtke, C., Weinshilboum, R. M., Wang, L., Ingle, J. N. & 7 others, Müller, V., Nekljudova, V., Weber, K. E., Rack, B., Rübner, M., Von Minckwitz, G. & Couch, F. J., Aug 1 2018, In : Journal of Clinical Oncology. 36, 22, p. 2281-2287 7 p.

Research output: Contribution to journalArticle

30 Scopus citations

DNA methyltransferase expression in triple-negative breast cancer predicts sensitivity to decitabine

Yu, J., Qin, B., Moyer, A. M., Nowsheen, S., Liu, T., Qin, S., Zhuang, Y., Liu, D., Lu, S. W., Kalari, K. R., Visscher, D. W., Copland, J. A., McLaughlin, S. A., Moreno-Aspitia, A., Northfelt, D. W., Gray, R. J., Lou, Z., Suman, V. J., Weinshilboum, R., Boughey, J. C. & 2 others, Goetz, M. P. & Wang, L., Jun 1 2018, In : Journal of Clinical Investigation. 128, 6, p. 2376-2388 13 p.

Research output: Contribution to journalArticle

28 Scopus citations

Effect of cytochrome CYP2C19 metabolizing activity on antidepressant response and side effects: Meta-analysis of data from genome-wide association studies

Fabbri, C., Tansey, K. E., Perlis, R. H., Hauser, J., Henigsberg, N., Maier, W., Mors, O., Placentino, A., Rietschel, M., Souery, D., Breen, G., Curtis, C., Lee, S. H., Newhouse, S., Patel, H., O'Donovan, M., Lewis, G., Jenkins, G., Weinshilboum, R. M., Farmer, A. & 7 others, Aitchison, K. J., Craig, I., McGuffin, P., Schruers, K., Biernacka, J. M., Uher, R. & Lewis, C. M., Aug 2018, In : European Neuropsychopharmacology. 28, 8, p. 945-954 10 p.

Research output: Contribution to journalArticle

12 Scopus citations

Germline genome-wide association studies in women receiving neoadjuvant chemotherapy with or without bevacizumab

Ingle, J. N., Kalari, K. R., Wickerham, D. L., Von Minckwitz, G., Fasching, P. A., Furukawa, Y., Mushiroda, T., Goetz, M. P., Barman, P., Carlson, E. E., Rastogi, P., Costantino, J. P., Cairns, J., Paik, S., Bear, H. D., Kubo, M., Wang, L. M., Wolmark, N. & Weinshilboum, R. M., Jan 1 2018, In : Pharmacogenetics and Genomics. 28, 6, p. 147-152 6 p.

Research output: Contribution to journalArticle

Ketamine and ketamine metabolites as novel estrogen receptor ligands: Induction of cytochrome P450 and AMPA glutamate receptor gene expression

Ho, M. F., Correia, C., Ingle, J. N., Kaddurah-Daouk, R., Wang, L. M., Kaufmann, S. H. & Weinshilboum, R. M., Jun 1 2018, In : Biochemical Pharmacology. 152, p. 279-292 14 p.

Research output: Contribution to journalArticle

8 Scopus citations

Machine learning helps identify new drug mechanisms in triple-negative breast cancer

Athreya, A. P., Gaglio, A. J., Cairns, J., Kalari, K. R., Weinshilboum, R. M., Wang, L., Kalbarczyk, Z. T. & Iyer, R. K., Jul 2018, In : IEEE Transactions on Nanobioscience. 17, 3, p. 251-259 9 p., 8401331.

Research output: Contribution to journalArticle

3 Scopus citations

Mapping depression rating scale phenotypes onto research domain criteria (RDoC) to inform biological research in mood disorders

The Mood Disorders Precision Medicine Consortium (MDPMC), Oct 1 2018, In : Journal of Affective Disorders. 238, p. 1-7 7 p.

Research output: Contribution to journalArticle

6 Scopus citations

New insights into the pharmacogenomics of antidepressant response from the GENDEP and STAR∗D studies: Rare variant analysis and high-density imputation

Fabbri, C., Tansey, K. E., Perlis, R. H., Hauser, J., Henigsberg, N., Maier, W., Mors, O., Placentino, A., Rietschel, M., Souery, D., Breen, G., Curtis, C., Sang-Hyuk, L., Newhouse, S., Patel, H., Guipponi, M., Perroud, N., Bondolfi, G., O'Donovan, M., Lewis, G. & 8 others, Biernacka, J. M., Weinshilboum, R. M., Farmer, A., Aitchison, K. J., Craig, I., McGuffin, P., Uher, R. & Lewis, C. M., May 22 2018, In : Pharmacogenomics Journal. 18, 3, p. 413-421 9 p.

Research output: Contribution to journalArticle

12 Scopus citations

PANOPLY: Omics-guided drug prioritization method tailored to an individual patient

Kalari, K. R., Sinnwell, J. P., Thompson, K. J., Tang, X., Carlson, E. E., Yu, J., Vedell, P. T., Ingle, J. N., Weinshilboum, R. M., Boughey, J. C., Wang, L., Goetz, M. P. & Suman, V., Jan 1 2018, In : JCO Clinical Cancer Informatics. 2018, 2, p. 1-12 12 p.

Research output: Contribution to journalArticle

Pathway-based analysis of genome-wide association data identified SNPs in HMMR as biomarker for chemotherapy- induced neutropenia in breast cancer patients

Bidadi, B., Liu, D., Kalari, K. R., Rubner, M., Hein, A., Beckmann, M. W., Rack, B., Janni, W., Fasching, P. A., Weinshilboum, R. M. & Wang, L., Mar 13 2018, In : Frontiers in Pharmacology. 9, MAR, 158.

Research output: Contribution to journalArticle

5 Scopus citations

Polygenic risk scores for major depressive disorder and neuroticism as predictors of antidepressant response: Meta-analysis of three treatment cohorts

Ward, J., Graham, N., Strawbridge, R. J., Ferguson, A., Jenkins, G., Chen, W., Hodgson, K., Frye, M., Weinshilboum, R., Uher, R., Lewis, C. M., Biernacka, J. & Smith, D. J., Sep 2018, In : PloS one. 13, 9, e0203896.

Research output: Contribution to journalArticle

10 Scopus citations

Research Directions in the Clinical Implementation of Pharmacogenomics: An Overview of US Programs and Projects

Volpi, S., Bult, C. J., Chisholm, R. L., Deverka, P. A., Ginsburg, G. S., Jacob, H. J., Kasapi, M., McLeod, H. L., Roden, D. M., Williams, M. S., Green, E. D., Rodriguez, L. L., Aronson, S., Cavallari, L. H., Denny, J. C., Dressler, L. G., Johnson, J. A., Klein, T. E., Leeder, J. S., Piquette-Miller, M. & 12 others, Perera, M., Rasmussen-Torvik, L. J., Rehm, H. L., Ritchie, M. D., Skaar, T. C., Wagle, N., Weinshilboum, R., Weitzel, K. W., Wildin, R., Wilson, J., Manolio, T. A. & Relling, M. V., May 2018, In : Clinical pharmacology and therapeutics. 103, 5, p. 778-786 9 p.

Research output: Contribution to journalArticle

31 Scopus citations
2 Scopus citations

SLCO1B1 genetic variation and hormone therapy in menopausal women

Moyer, A., De Andrade, M., Faubion, S. S., Kapoor, E., Dudenkov, T., Weinshilboum, R. M. & Miller, V. M., Aug 1 2018, In : Menopause (New York, N.Y.). 25, 8, p. 877-882 6 p.

Research output: Contribution to journalArticle

3 Scopus citations

TCL1A, a novel transcription factor and a coregulator of nuclear factor kB p65: Single nucleotide polymorphism and estrogen dependences

Ho, M. F., Lummertz da Rocha, E., Zhang, C., Ingle, J. N., Goss, P. E., Shepherd, L. E., Kubo, M., Wang, L., Li, H. & Weinshilboum, R. M., Jun 2018, In : Journal of Pharmacology and Experimental Therapeutics. 365, 3, p. 700-710 11 p.

Research output: Contribution to journalArticle

2 Scopus citations
2017

A comprehensive analysis of breast cancer microbiota and host gene expression

Thompson, K. J., Ingle, J. N., Tang, X., Chia, N., Jeraldo, P. R., Walther-Antonio, M. R., Kandimalla, K. K., Johnson, S., Yao, J. Z., Harrington, S. C., Suman, V. J., Wang, L., Weinshilboum, R. L., Boughey, J. C., Kocher, J. P., Nelson, H., Goetz, M. P. & Kalari, K. R., Nov 2017, In : PloS one. 12, 11, e0188873.

Research output: Contribution to journalArticle

18 Scopus citations

Calmodulin-like protein 3 is an estrogen receptor alpha coregulator for gene expression and drug response in a SNP, estrogen, and SERM-dependent fashion

Qin, S., Ingle, J. N., Liu, M., Yu, J., Wickerham, D. L., Kubo, M., Weinshilboum, R. M. & Wang, L., Aug 18 2017, In : Breast Cancer Research. 19, 1, 95.

Research output: Contribution to journalArticle

11 Scopus citations

Clinical validation of genetic variants associated with in vitro chemotherapy-related lymphoblastoid cell toxicity

Fasching, P. A., Häberle, L., Rack, B., Li, L., Hein, A., Ekici, A. B., Reis, A., Lux, M. P., Cunningham, J. M., Ruebner, M., Jenkins, G., Fridley, B., Schneeweiss, A., Tesch, H., Lichtenegger, W., Fehm, T., Heinrich, G., Rezai, M., Beckmann, M. W., Janni, W. & 2 others, Weinshilboum, R. M. & Wang, L., Jan 1 2017, In : Oncotarget. 8, 44, p. 78133-78143 11 p.

Research output: Contribution to journalArticle

2 Scopus citations