Richard M Weinshilboum, MD

  • 28270 Citations
  • 85 Scopus h-Index
1968 …2020

Research output per year

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Research Output

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Review article

Systematic review of the evidence on the cost-effectiveness of pharmacogenomics-guided treatment for cardiovascular diseases

Zhu, Y., Swanson, K. M., Rojas, R. L., Wang, Z., St. Sauver, J. L., Visscher, S. L., Prokop, L. J., Bielinski, S. J., Wang, L., Weinshilboum, R. & Borah, B. J., Jan 1 2019, (Accepted/In press) In : Genetics in Medicine.

Research output: Contribution to journalReview article

Open Access
6 Scopus citations
2018

Genome-wide association study of response to methotrexate in early rheumatoid arthritis patients

on behalf of the MATURA, and PAMERA & Consortia, Jul 1 2018, In : Pharmacogenomics Journal. 18, 4, p. 528-538 11 p.

Research output: Contribution to journalReview article

17 Scopus citations

The role of the aryl hydrocarbon receptor (AHR) in immune and inflammatory diseases

Neavin, D. R., Liu, D., Ray, B. & Weinshilboum, R. M., Dec 2018, In : International journal of molecular sciences. 19, 12, 3851.

Research output: Contribution to journalReview article

17 Scopus citations
2017
26 Scopus citations

Pharmacogenomics: Precision Medicine and Drug Response

Weinshilboum, R. M. & Wang, L., Nov 2017, In : Mayo Clinic proceedings. 92, 11, p. 1711-1722 12 p.

Research output: Contribution to journalReview article

37 Scopus citations
2013

Genome-wide association studies in pharmacogenomics: Successes and lessons

Motsinger-Reif, A. A., Jorgenson, E., Relling, M. V., Kroetz, D. L., Weinshilboum, R., Cox, N. J. & Roden, D. M., Aug 1 2013, In : Pharmacogenetics and genomics. 23, 8, p. 383-394 12 p.

Research output: Contribution to journalReview article

76 Scopus citations

Implementing genomic medicine in the clinic: The future is here

Manolio, T. A., Chisholm, R. L., Ozenberger, B., Roden, D. M., Williams, M. S., Wilson, R., Bick, D., Bottinger, E. P., Brilliant, M. H., Eng, C., Frazer, K. A., Korf, B., Ledbetter, D. H., Lupski, J. R., Marsh, C., Mrazek, D., Murray, M. F., O'Donnell, P. H., Rader, D. J., Relling, M. V. & 5 others, Shuldiner, A. R., Valle, D., Weinshilboum, R., Green, E. D. & Ginsburg, G. S., Apr 1 2013, In : Genetics in Medicine. 15, 4, p. 258-267 10 p.

Research output: Contribution to journalReview article

320 Scopus citations
2012

Pharmacogenomics and patient care: One size does not fit all

Giacomini, K. M., Yee, S. W., Ratain, M. J., Weinshilboum, R. M., Kamatani, N. & Nakamura, Y., Sep 26 2012, In : Science translational medicine. 4, 153, 153ps18.

Research output: Contribution to journalReview article

27 Scopus citations
2011

CYP2C19 variation and citalopram response

Mrazek, D. A., Biernacka, J. M., O'Kane, D. J., Black, J. L., Cunningham, J. M., Drews, M. S., Snyder, K. A., Stevens, S. R., Rush, A. J. & Weinshilboum, R. M., Jan 1 2011, In : Pharmacogenetics and genomics. 21, 1, p. 1-9 9 p.

Research output: Contribution to journalReview article

86 Scopus citations

Genomics and drug response

Wang, L., McLeod, H. L. & Weinshilboum, R. M., Mar 24 2011, In : New England Journal of Medicine. 364, 12, p. 1144-1153 10 p.

Research output: Contribution to journalReview article

429 Scopus citations

The impact of pharmacogenomics on the management of cardiac disease

Pereira, N. L. & Weinshilboum, R. M., Oct 1 2011, In : Clinical pharmacology and therapeutics. 90, 4, p. 493-495 3 p.

Research output: Contribution to journalReview article

13 Scopus citations
2010

Coprescription of tamoxifen and medications that inhibit CYP2D6

Sideras, K., Ingle, J. N., Ames, M. M., Loprinzi, C. L., Mrazek, D. P., Black, J. L., Weinshilboum, R. M., Hawse, J. R., Spelsberg, T. C. & Goetz, M. P., Jun 1 2010, In : Journal of Clinical Oncology. 28, 16, p. 2768-2776 9 p.

Research output: Contribution to journalReview article

100 Scopus citations

Very important pharmacogene summary: Thiopurine S-methyltransferase

Wang, L., Pelleymounter, L., Weinshilboum, R., Johnson, J. A., Hebert, J. M., Altman, R. B. & Klein, T. E., Jun 1 2010, In : Pharmacogenetics and genomics. 20, 6, p. 401-405 5 p.

Research output: Contribution to journalReview article

28 Scopus citations
2009

Endocrine therapy in 2009: Consideration of the tumor and the host

Goetz, M. P., Ames, M. M., Weinshilboum, R. M. & Ingle, J. N., Feb 1 2009, In : Oncology. 23, 2, p. 150-151+154

Research output: Contribution to journalReview article

Sulfotransferase gene copy number variation: Pharmacogenetics and function

Hebbring, S. J., Moyer, A. M. & Weinshilboum, R. M., Mar 1 2009, In : Cytogenetic and Genome Research. 123, 1-4, p. 205-210 6 p.

Research output: Contribution to journalReview article

24 Scopus citations

Very important pharmacogene summary: Sulfotransferase 1A1

Hildebrandt, M., Adjei, A., Weinshilboum, R., Johnson, J. A., Berlin, D. S., Klein, T. E. & Altman, R. B., Jun 1 2009, In : Pharmacogenetics and genomics. 19, 6, p. 404-406 3 p.

Research output: Contribution to journalReview article

13 Scopus citations
2008

Metabolomics: A global biochemical approach to drug response and disease

Kaddurah-Daouk, R., Kristal, B. S. & Weinshilboum, R. M., Jun 2 2008, In : Annual Review of Pharmacology and Toxicology. 48, p. 653-683 31 p.

Research output: Contribution to journalReview article

453 Scopus citations
2007

The Pharmacogenetics Research Network: From SNP discovery to clinical drug response

Giacomini, K. M., Brett, C. M., Altman, R. B., Benowitz, N. L., Dolan, M. E., Flockhart, D. A., Johnson, J. A., Hayes, D. F., Klein, T., Krauss, R. M., Kroetz, D. L., McLeod, H. L., Nguyen, A. T., Ratain, M. J., Relling, M. V., Reus, V., Roden, D. M., Schaefer, C. A., Shuldiner, A. R., Skaar, T. & 6 others, Tantisira, K., Tyndale, R. F., Wang, L., Weinshilboum, R. M., Weiss, S. T. & Zineh, I., Mar 1 2007, In : Clinical pharmacology and therapeutics. 81, 3, p. 328-345 18 p.

Research output: Contribution to journalReview article

182 Scopus citations
2006

Pharmacogenomics: Challenges and opportunities

Roden, D. M., Altman, R. B., Benowitz, N. L., Flockhart, D. A., Giacomini, K. M., Johnson, J. A., Krauss, R. M., McLeod, H. L., Ratain, M. J., Relling, M. V., Ring, H. Z., Shuldiner, A. R., Weinshilboum, R. M. & Weiss, S. T., May 15 2006, In : Annals of internal medicine. 145, 10, p. 749-757 9 p.

Research output: Contribution to journalReview article

189 Scopus citations

Pharmacogenomics: catechol O-methyltransferase to thiopurine S-methyltransferase.

Weinshilboum, R. M., Jan 1 2006, In : Cellular and molecular neurobiology. 26, 4-6, p. 539-561 23 p.

Research output: Contribution to journalReview article

47 Scopus citations

Role of the glutathione metabolic pathway in lung cancer treatment and prognosis: A review

Yang, P., Ebbert, J. O., Sun, Z. & Weinshilboum, R. M., Apr 10 2006, In : Journal of Clinical Oncology. 24, 11, p. 1761-1769 9 p.

Research output: Contribution to journalReview article

94 Scopus citations

Thiopurine S-methyltransferase pharmacogenetics: Insights, challenges and future directions

Wang, L. & Weinshilboum, R., Mar 13 2006, In : Oncogene. 25, 11, p. 1629-1638 10 p.

Research output: Contribution to journalReview article

161 Scopus citations
2004

Pharmacogenomics: Bench to bedside

Weinshilboum, R. & Wang, L., Sep 1 2004, In : Nature Reviews Drug Discovery. 3, 9, p. 739-748 10 p.

Research output: Contribution to journalReview article

217 Scopus citations
2003

Inheritance and drug response

Weinshilboum, R., Feb 6 2003, In : New England Journal of Medicine. 348, 6, p. 529-537 9 p.

Research output: Contribution to journalReview article

853 Scopus citations
2000

Estrogen metabolism by conjugation.

Raftogianis, R., Creveling, C., Weinshilboum, R. & Weisz, J., 2000, In : Journal of the National Cancer Institute. Monographs. 27, p. 113-124 12 p.

Research output: Contribution to journalReview article

Open Access
215 Scopus citations
1999

Methylation pharmacogenetics: Catechol O-methyltransferase, thiopurine methyltransferase, and histamine N-methyltransferase

Weinshilboum, R. M., Otterness, D. M. & Szumlanski, C. L., May 22 1999, In : Annual Review of Pharmacology and Toxicology. 39, p. 19-52 34 p.

Research output: Contribution to journalReview article

434 Scopus citations
1997

Sulfotransferase molecular biology: cDNAs and genes

Weinshilboum, R. M., Otterness, D. M., Aksoy, I. A., Wood, T. C., Her, C. & Raftogianis, R. B., Jan 1997, In : FASEB Journal. 11, 1, p. 3-14 12 p.

Research output: Contribution to journalReview article

376 Scopus citations
1988

Phenol sulfotransferase inheritance

Weinshilboum, R., Mar 1 1988, In : Cellular and molecular neurobiology. 8, 1, p. 27-34 8 p.

Research output: Contribution to journalReview article

15 Scopus citations
1987

Pharmacogenetics of methyl conjugation and thiopurine drug toxicity

Weinshilboum, R., Aug 1987, In : BioEssays. 7, 2, p. 78-82 5 p.

Research output: Contribution to journalReview article

4 Scopus citations
1983

Pharmacogenetics of methyl conjugation.

Weinshilboum, R. M., Dec 1 1983, In : Progress in clinical and biological research. 135, p. 167-181 15 p.

Research output: Contribution to journalReview article

6 Scopus citations
1979

Hypertension, a biomedical genetic approach.

Weinshilboum, R., Dec 1 1979, In : Progress in clinical and biological research. 32, p. 157-181 25 p.

Research output: Contribution to journalReview article

2 Scopus citations
1978

Serum dopamine β-hydroxylase

Weinshilboum, R. M., Dec 1 1978, In : Pharmacological Reviews. 30, 2, p. 133-166 34 p.

Research output: Contribution to journalReview article

107 Scopus citations
1972

Catecholamines

Axelrod, J. & Weinshilboum, R., Aug 3 1972, In : New England Journal of Medicine. 287, 5, p. 237-242 6 p.

Research output: Contribution to journalReview article

119 Scopus citations