Konstantinos N Lazaridis, MD, FACP, AGAF

  • 5790 Citations
  • 39 Scopus h-Index
1993 …2020

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2020

An update on primary sclerosing cholangitis epidemiology, outcomes and quantification of alkaline phosphatase variability in a population-based cohort

Bakhshi, Z., Hilscher, M. B., Gores, G. J., Harmsen, W. S., Viehman, J. K., LaRusso, N. F., Gossard, A. A., Lazaridis, K. N., Lindor, K. D. & Eaton, J. E., May 1 2020, In : Journal of gastroenterology. 55, 5, p. 523-532 10 p.

Research output: Contribution to journalArticle

Changes in Liver Stiffness, Measured by Magnetic Resonance Elastography, Associated With Hepatic Decompensation in Patients With Primary Sclerosing Cholangitis

Eaton, J. E., Sen, A., Hoodeshenas, S., Schleck, C. D., Harmsen, W. S., Gores, G. J., LaRusso, N. F., Gossard, A. A., Lazaridis, K. N. & Venkatesh, S. K., Jun 2020, In : Clinical Gastroenterology and Hepatology. 18, 7, p. 1576-1583.e1

Research output: Contribution to journalArticle

2 Scopus citations

Metabolomic biomarkers are associated with mortality in patients with cirrhosis caused by primary biliary cholangitis or primary sclerosing cholangitis

Mindikoglu, A. L., Coarfa, C., Opekun, A. R., Shah, V. H., Arab, J. P., Lazaridis, K. N., Putluri, N., Ambati, C. R., Robertson, M. J., Devaraj, S., Jalal, P. K., Rana, A., Goss, J. A., Dowling, T. C., Weir, M. R., Seliger, S. L., Raufman, J. P., Bernard, D. W. & Vierling, J. M., 2020, In : Future Science OA. 6, 2

Research output: Contribution to journalArticle

Open Access
1 Scopus citations

Primary Sclerosing Cholangitis Risk Estimate Tool (PREsTo) Predicts Outcomes of the Disease: A Derivation and Validation Study Using Machine Learning

Eaton, J. E., Vesterhus, M., McCauley, B. M., Atkinson, E. J., Schlicht, E. M., Juran, B. D., Gossard, A. A., LaRusso, N. F., Gores, G. J., Karlsen, T. H. & Lazaridis, K. N., Jan 1 2020, In : Hepatology. 71, 1, p. 214-224 11 p.

Research output: Contribution to journalArticle

10 Scopus citations
2019

Clinical Applications and Utility of a Precision Medicine Approach for Patients With Unexplained Cytopenias

Mangaonkar, A. A., Ferrer, A., Pinto e Vairo, F., Cousin, M. A., Kuisle, R. J., Gangat, N., Hogan, W. J., Litzow, M. R., McAllister, T. M., Klee, E. W., Lazaridis, K. N., Stewart, A. K. & Patnaik, M. M., Sep 2019, In : Mayo Clinic proceedings. 94, 9, p. 1753-1768 16 p.

Research output: Contribution to journalArticle

2 Scopus citations
8 Scopus citations
1 Scopus citations
2018

Genetic association analysis identifies variants associated with disease progression in primary sclerosing cholangitis

Müller, T., Alberts, R., De Vries, E. M. G., Goode, E. C., Jiang, X., Sampaziotis, F., Rombouts, K., Böttcher, K., Folseraas, T., Weismüller, T. J., Mason, A. L., Wang, W., Alexander, G., Alvaro, D., Bergquist, A., Björkström, N. K., Beuers, U., Björnsson, E., Boberg, K. M., Bowlus, C. L. & 54 others, Bragazzi, M. C., Carbone, M., Chazouillères, O., Cheung, A., Dalekos, G., Eaton, J., Eksteen, B., Ellinghaus, D., Färkkilä, M., Festen, E. A. M., Floreani, A., Franceschet, I., Gotthardt, D. N., Hirschfield, G. M., Hoek, B. V., Holm, K., Hohenester, S., Hov, J. R., Imhann, F., Invernizzi, P., Juran, B. D., Lenzen, H., Lieb, W., Liu, J. Z., Marschall, H. U., Marzioni, M., Melum, E., Milkiewicz, P., Pares, A., Rupp, C., Rust, C., Sandford, R. N., Schramm, C., Schreiber, S., Schrumpf, E., Silverberg, M. S., Srivastava, B., Sterneck, M., Teufel, A., Vallier, L., Verheij, J., Vila, A. V., De Vries, B., Zachou, K., Chapman, R. W., Manns, M. P., Pinzani, M., Rushbrook, S. M., Lazaridis, K. N., Franke, A., Anderson, C. A., Karlsen, T. H., Ponsioen, C. Y. & Weersma, R. K., Aug 1 2018, In : Gut. 67, 8, p. 1517-1524 8 p.

Research output: Contribution to journalArticle

17 Scopus citations

Metabolomic profiling of portal blood and bile reveals metabolic signatures of primary sclerosing cholangitis

Tietz-Bogert, P. S., Kim, M., Cheung, A., Tabibian, J. H., Heimbach, J. K., Rosen, C. B., Nandakumar, M., Lazaridis, K. N., Larusso, N. F., Sung, J. & O’hara, S. P., Oct 16 2018, In : International journal of molecular sciences. 19, 10, 3188.

Research output: Contribution to journalArticle

6 Scopus citations

PNPLA3 association with alcoholic liver disease in a cohort of heavy drinkers

Kolla, B. P., Schneekloth, T. D., Biernacka, J. M., Shah, V., Lazaridis, K. N., Geske, J. & Karpyak, V. M., Jan 1 2018, In : Alcohol and Alcoholism. 53, 4, p. 357-360 4 p.

Research output: Contribution to journalArticle

6 Scopus citations

Primary biliary cholangitis, DNA, and beyond: The Relative contribution of genes

Gulamhusein, A. F. & Lazaridis, K. N., Jan 1 2018, (Accepted/In press) In : Hepatology.

Research output: Contribution to journalArticle

1 Scopus citations
2017

Doublecortin domain containing protein 2 (DCDC2) genetic variants in primary sclerosing cholangitis

Cheung, A. C., Juran, B. D., Moore, R. M., La Russo, N. F. & Lazaridis, K. N., 2017, (Accepted/In press) In : Journal of Hepatology.

Research output: Contribution to journalArticle

1 Scopus citations

Emerging pharmacologic therapies for primary sclerosing cholangitis

Cheung, A. C., Lazaridis, K. N., La Russo, N. F. & Gores, G. J., Mar 2 2017, (Accepted/In press) In : Current Opinion in Gastroenterology.

Research output: Contribution to journalArticle

6 Scopus citations

Epigenetics in the Primary Biliary Cholangitis and Primary Sclerosing Cholangitis

Cheung, A. C., La Russo, N. F., Gores, G. J. & Lazaridis, K. N., May 1 2017, In : Seminars in Liver Disease. 37, 2, p. 159-174 16 p.

Research output: Contribution to journalArticle

10 Scopus citations

Experience with precision genomics and tumor board, indicates frequent target identification, but barriers to delivery

Bryce, A. H., Egan, J. B., Borad, M. J., Keith Stewart, A., Nowakowski, G. S., Chanan-Khan, A., Patnaik, M. M., Ansell, S. M., Banck, M. S., Robinson, S. I., Mansfield, A. S., Klee, E. W., Oliver, G. R., McCormick, J. B., Huneke, N. E., Tagtow, C. M., Jenkins, R. B., Rumilla, K. M., Kerr, S. E., Kocher, J. P. A. & 5 others, Beck, S. A., Fernandez-Zapico, M. E., Farrugia, G., Lazaridis, K. N. & McWilliams, R. R., 2017, In : Oncotarget. 8, 16, p. 27145-27154 10 p.

Research output: Contribution to journalArticle

20 Scopus citations

Genome-wide association study of primary sclerosing cholangitis identifies new risk loci and quantifies the genetic relationship with inflammatory bowel disease

Ji, S. G., Juran, B. D., Mucha, S., Folseraas, T., Jostins, L., Melum, E., Kumasaka, N., Atkinson, E. J., Schlicht, E. M., Liu, J. Z., Shah, T., Gutierrez-Achury, J., Boberg, K. M., Bergquist, A., Vermeire, S., Eksteen, B., Durie, P. R., Farkkila, M., Müller, T., Schramm, C. & 50 others, Sterneck, M., Weismüller, T. J., Gotthardt, D. N., Ellinghaus, D., Braun, F., Teufel, A., Laudes, M., Lieb, W., Jacobs, G., Beuers, U., Weersma, R. K., Wijmenga, C., Marschall, H. U., Milkiewicz, P., Pares, A., Kontula, K., Chazouillères, O., Invernizzi, P., Goode, E., Spiess, K., Moore, C., Sambrook, J., Ouwehand, W. H., Roberts, D. J., Danesh, J., Floreani, A., Gulamhusein, A. F., Eaton, J. E., Schreiber, S., Coltescu, C., Bowlus, C. L., Luketic, V. A., Odin, J. A., Chopra, K. B., Kowdley, K. V., Chalasani, N., Manns, M. P., Srivastava, B., Mells, G., Sandford, R. N., Alexander, G., Gaffney, D. J., Chapman, R. W., Hirschfield, G. M., De Andrade, M., Rushbrook, S. M., Franke, A., Karlsen, T. H., Lazaridis, K. N. & Anderson, C. A., Jan 31 2017, In : Nature Genetics. 49, 2, p. 269-273 5 p.

Research output: Contribution to journalArticle

64 Scopus citations

HLA haplotypes in primary sclerosing cholangitis patients of admixed and non-European ancestry

The UK-PSC Consortium, Oct 2017, In : HLA. 90, 4, p. 228-233 6 p.

Research output: Contribution to journalArticle

Improving Therapeutic Odyssey: Preemptive Pharmacogenomics Utility in Patient Care

Lazaridis, K. N., Jan 1 2017, In : Clinical Pharmacology and Therapeutics. 101, 1, p. 39-41 3 p.

Research output: Contribution to journalArticle

4 Scopus citations

Molecular modeling and functional analysis of exome sequencing-derived variants of unknown significance identify a novel, constitutively active FGFR2 mutant in cholangiocarcinoma

Egan, J. B., Marks, D. L., Hogenson, T. L., Vrabel, A. M., Sigafoos, A. N., Tolosa, E. J., Carr, R. M., Safgren, S. L., Hesles, E. E., Almada, L. L., Romecin-Duran, P. A., Iguchi, E., Ala'Aldeen, A., Kocher, J. P. A., Oliver, G. R., Prodduturi, N., Mead, D. W., Hossain, A., Huneke, N. E., Tagtow, C. M. & 43 others, Ailawadhi, S., Ansell, S. M., Banck, M. S., Bryce, A. H., Carballido, E. M., Chanan-Khan, A. A., Curtis, K. K., Resnik, E., Gawryletz, C. D., Go, R. S., Halfdanarson, T. R., Ho, T. H., Joseph, R. W., Kapoor, P., Mansfield, A. S., Meurice, N., Rao, A. A. N., Nowakowski, G. S., Pardanani, A., Parikh, S. A., Cheville, J. C., Feldman, A. L., Ramanathan, R. K., Robinson, S. I., Tibes, R., Finnes, H. D., McCormick, J. B., McWilliams, R. R., Jatoi, A., Patnaik, M. M., Silva, A. C., Wieben, E. D., McAllister, T. M., Rumilla, K. M., Kerr, S. E., Lazaridis, K. N., Farrugia, G., Keith Stewart, A., Clark, K. J., Kennedy, E. J., Klee, E. W., Borad, M. J. & Fernandez-Zapico, M. E., Jan 1 2017, In : JCO Precision Oncology. 2017, 1, p. 1-13 13 p.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations

Patient Age, Sex, and Inflammatory Bowel Disease Phenotype Associate With Course of Primary Sclerosing Cholangitis

on behalf of the & International PSC Study Group, Jun 2017, In : Gastroenterology. 152, 8, p. 1975-1984.e8

Research output: Contribution to journalArticle

121 Scopus citations

Pharmacogenomic findings from clinical whole exome sequencing of diagnostic odyssey patients

Cousin, M. A., Matey, E. T., Blackburn, P. R., Boczek, N. J., McAllister, T. M., Kruisselbrink, T. M., Babovic-Vuksanovic, D., Lazaridis, K. N. & Klee, E. W., Jan 1 2017, In : Molecular Genetics and Genomic Medicine. 5, 3, p. 269-279 11 p.

Research output: Contribution to journalArticle

5 Scopus citations
5 Scopus citations

The prevalence of diseases caused by lysosome-related genes in a cohort of undiagnosed patients

Vairo, F. P., Boczek, N. J., Cousin, M. A., Kaiwar, C., Blackburn, P. R., Conboy, E., Lanpher, B. C., Gavrilova, R. H., Pichurin, P. N., Lazaridis, K. N., Babovic-Vuksanovic, D. & Klee, E. W., Dec 1 2017, In : Molecular Genetics and Metabolism Reports. 13, p. 46-51 6 p.

Research output: Contribution to journalArticle

8 Scopus citations

Variations in primary sclerosing cholangitis across the age spectrum

Eaton, J. E., McCauley, B. M., Atkinson, E. J., Juran, B. D., Schlicht, E. M., De Andrade, M. & Lazaridis, K. N., Oct 1 2017, In : Journal of Gastroenterology and Hepatology (Australia). 32, 10, p. 1763-1768 6 p.

Research output: Contribution to journalArticle

9 Scopus citations
2016

Analysis of five chronic inflammatory diseases identifies 27 new associations and highlights disease-specific patterns at shared loci

Ellinghaus, D., Jostins, L., Spain, S. L., Cortes, A., Bethune, J., Han, B., Park, Y. R., Raychaudhuri, S., Pouget, J. G., Hübenthal, M., Folseraas, T., Wang, Y., Esko, T., Metspalu, A., Westra, H. J., Franke, L., Pers, T. H., Weersma, R. K., Collij, V., D'Amato, M. & 25 others, Halfvarson, J., Jensen, A. B., Lieb, W., Degenhardt, F., Forstner, A. J., Hofmann, A., Schreiber, S., Mrowietz, U., Juran, B. D., Lazaridis, K. N., Brunak, SØ., Dale, A. M., Trembath, R. C., Weidinger, S., Weichenthal, M., Ellinghaus, E., Elder, J. T., Barker, J. N. W. N., Andreassen, O. A., McGovern, D. P., Karlsen, T. H., Barrett, J. C., Parkes, M., Brown, M. A. & Franke, A., May 1 2016, In : Nature Genetics. 48, 5, p. 510-518 9 p.

Research output: Contribution to journalArticle

217 Scopus citations

Clinical characteristics and platelet phenotype in a family with RUNX1 mutated thrombocytopenia

Perez Botero, J., Chen, D., Cousin, M. A., Majerus, J. A., Coon, L. M., Kruisselbrink, T. M., Klee, E. W., Lazaridis, K. N., Pruthi, R. K. & Patnaik, M. M., Dec 8 2016, (Accepted/In press) In : Leukemia and Lymphoma. p. 1-5 5 p.

Research output: Contribution to journalArticle

6 Scopus citations

Clinical Implementation of Integrated Genomic Profiling in Patients with Advanced Cancers

Borad, M. J., Egan, J. B., Condjella, R. M., Liang, W. S., Fonseca, R., Ritacca, N. R., McCullough, A. E., Barrett, M., Hunt, K. S., Champion, M. D., Patel, M. D., Young, S. W., Silva, A. C., Ho, T. H., Halfdanarson, T. R., Mc Williams, R. R., Lazaridis, K. N., Ramanathan, R. K., Baker, A., Aldrich, J. & 17 others, Kurdoglu, A., Izatt, T., Christoforides, A., Cherni, I., Nasser, S., Reiman, R., Cuyugan, L., McDonald, J., Adkins, J., Mastrian, S. D., Valdez, R., Jaroszewski, D. E., Von Hoff, D. D., Craig, D. W., Stewart, A. K., Carpten, J. D. & Bryce, A. H., 2016, In : Scientific Reports. 6, 1, 25.

Research output: Contribution to journalArticle

11 Scopus citations

Duration of inflammatory bowel disease is associated with increased risk of cholangiocarcinoma in patients with primary sclerosing cholangitis and IBD

Gulamhusein, A. F., Eaton, J. E., Tabibian, J. H., Atkinson, E. J., Juran, B. D. & Lazaridis, K. N., May 1 2016, In : American Journal of Gastroenterology. 111, 5, p. 705-711 7 p.

Research output: Contribution to journalArticle

38 Scopus citations

Low incidence of primary biliary cirrhosis (PBC) in the first-degree relatives of PBC probands after 8 years of follow-up

Gulamhusein, A. F., Juran, B. D., Atkinson, E. J., Mccauley, B., Schlicht, E. & Lazaridis, K. N., 2016, (Accepted/In press) In : Liver International.

Research output: Contribution to journalArticle

10 Scopus citations

Molecular cytology genotyping of primary and metastatic GI stromal tumors by using a custom two-gene targeted next-generation sequencing panel with therapeutic intent

Gleeson, F. C., Kerr, S. E., Kipp, B. R., Voss, J. S., Minot, D. M., Tu, Z. J., Henry, M. R., Vasmatzis, G., Cheville, J. C., Lazaridis, K. N. & Levy, M. J., Jan 24 2016, (Accepted/In press) In : Gastrointestinal Endoscopy.

Research output: Contribution to journalArticle

4 Scopus citations

Outcome of Whole Exome Sequencing for Diagnostic Odyssey Cases of an Individualized Medicine Clinic: The Mayo Clinic Experience

Lazaridis, K. N., Schahl, K. A., Cousin, M. A., Babovic-Vuksanovic, D., Riegert-Johnson, D. L., Gavrilova, R. H., McAllister, T. M., Lindor, N. M., Abraham, R. S., Ackerman, M. J., Pichurin, P. N., Deyle, D. R., Gavrilov, D. K., Hand, J. L., Klee, E. W., Stephens, M. C., Wick, M. J., Atkinson, E. J., Linden, D. R., Ferber, M. J. & 19 others, Wieben, E. D., Farrugia, G., Baudhuin, L. M., Beck, S. A., Beek, G. J., Go, R. S., Guthrie, K. J., Hovan, M. J., Hunt, K. S., Kemppainen, J. L., Kruisselbrink, T. M., McCormick, J. B., McLaughlin, B. M., Murphree, M. I., Niewold, T. B., Oglesbee, D., Reed, A., Thibodeau, S. N. & Thorland, E. C., Mar 1 2016, In : Mayo Clinic Proceedings. 91, 3, p. 297-307 11 p.

Research output: Contribution to journalArticle

58 Scopus citations

Performance of magnetic resonance elastography in primary sclerosing cholangitis

Eaton, J. E., Dzyubak, B., Venkatesh, S. K., Smyrk, T. C., Gores, G. J., Ehman, R. L., La Russo, N. F., Gossard, A. A. & Lazaridis, K. N., Jun 1 2016, In : Journal of Gastroenterology and Hepatology (Australia). 31, 6, p. 1184-1190 7 p.

Research output: Contribution to journalArticle

40 Scopus citations

Targeted next generation sequencing of endoscopic ultrasound acquired cytology from ampullary and pancreatic adenocarcinoma has the potential to aid patient stratification for optimal therapy selection

Gleeson, F. C., Kerr, S. E., Kipp, B. R., Voss, J. S., Minot, D. M., Tu, Z. J., Henry, M. R., Graham, R. P., Vasmatzis, G., Cheville, J. C., Lazaridis, K. N. & Levy, M. J., 2016, In : Oncotarget. 7, 34, p. 54526-54536 11 p.

Research output: Contribution to journalArticle

39 Scopus citations
2015

A comprehensive assessment of environmental exposures among 1000 North American patients with primary sclerosing cholangitis, with and without inflammatory bowel disease

Eaton, J. E., Juran, B. D., Atkinson, E. J., Schlicht, E. M., Xie, X., De Andrade, M., Lammert, C. S., Luketic, V. A., Odin, J. A., Koteish, A. A., Kowdley, K. V., Chopra, K. B., Hirschfield, G. M., Chalasani, N. P. & Lazaridis, K. N., May 1 2015, In : Alimentary Pharmacology and Therapeutics. 41, 10, p. 980-990 11 p.

Research output: Contribution to journalArticle

19 Scopus citations

Association between HLA haplotypes and increased serum levels of IgG4 in patients with primary sclerosing cholangitis

Berntsen, N. L., Klingenberg, O., Juran, B. D., Benito De Valle, M., Lindkvist, B., Lazaridis, K. N., Boberg, K. M., Karlsen, T. H. & Hov, J. R., May 1 2015, In : Gastroenterology. 148, 5, p. 924-927.e2

Research output: Contribution to journalArticle

26 Scopus citations

Association between variants in inflammation and cancer-associated genes and risk and survival of cholangiocarcinoma

Chaiteerakij, R., Juran, B. D., Aboelsoud, M. M., Harmsen, W. S., Moser, C. D., Giama, N. H., Allotey, L. K., Mettler, T. A., Baichoo, E., Zhang, X., Therneau, T. M., Lazaridis, K. N. & Roberts, L. R., Oct 1 2015, In : Cancer Medicine. 4, 10, p. 1599-1602 4 p.

Research output: Contribution to journalArticle

5 Scopus citations

Endoscopic ultrasound fine-needle aspiration cytology mutation profiling using targeted next-generation sequencing: personalized care for rectal cancer

Gleeson, F. C., Kipp, B. R., Voss, J. S., Campion, M. B., Minot, D. M., Tu, Z. J., Klee, E. W., Sciallis, A. P., Graham, R., Lazaridis, K. N., Henry, M. R. & Levy, M. J., Jun 1 2015, In : American Journal of Clinical Pathology. 143, 6, p. 879-888 10 p.

Research output: Contribution to journalArticle

28 Scopus citations

Frequency of mitogen-activated protein kinase and phosphoinositide 3-kinase signaling pathway pathogenic alterations in EUS-FNA sampled malignant lymph nodes in rectal cancer with theranostic potential

Gleeson, F. C., Kipp, B. R., Voss, J. S., Campion, M. B., Minot, D. M., Tu, Z. J., Klee, E. W., Graham, R., Lazaridis, K. N., Henry, M. R. & Levy, M. J., Sep 1 2015, In : Gastrointestinal Endoscopy. 82, 3, p. 550-556 7 p.

Research output: Contribution to journalArticle

3 Scopus citations

Genome-Wide Association Studies in Primary Biliary Cirrhosis

Gulamhusein, A. F., Juran, B. D. & Lazaridis, K. N., Nov 1 2015, In : Seminars in Liver Disease. 35, 4, p. 392-401 10 p.

Research output: Contribution to journalArticle

29 Scopus citations

International genome-wide meta-analysis identifies new primary biliary cirrhosis risk loci and targetable pathogenic pathways

Cordell, H. J., Han, Y., Mells, G. F., Li, Y., Hirschfield, G. M., Greene, C. S., Xie, G., Juran, B. D., Zhu, D., Qian, D. C., Floyd, J. A. B., Morley, K. I., Prati, D., Lleo, A., Cusi, D., Gershwin, M. E., Anderson, C. A., Lazaridis, K. N., Invernizzi, P., Seldin, M. F. & 441 others, Sandford, R. N., Amos, C. I., Siminovitch, K. A., Schlicht, E. M., Lammert, C., Atkinson, E. J., Chan, L. L., De Andrade, M., Balschun, T., Mason, A. L., Myers, R. P., Zhang, J., Milkiewicz, P., Qu, J., Odin, J. A., Luketic, V. A., Bacon, B. R., Bodenheimer, H. C., Liakina, V., Vincent, C., Levy, C., Gregersen, P. K., Almasio, P. L., Alvaro, D., Andreone, P., Andriulli, A., Barlassina, C., Battezzati, P. M., Benedetti, A., Bernuzzi, F., Bianchi, I., Bragazzi, M. C., Brunetto, M., Bruno, S., Casella, G., Coco, B., Colli, A., Colombo, M., Colombo, S., Cursaro, C., Crocè, L. S., Crosignani, A., Donato, M. F., Elia, G., Fabris, L., Ferrari, C., Floreani, A., Foglieni, B., Fontana, R., Galli, A., Lazzari, R., Macaluso, F., Malinverno, F., Marra, F., Marzioni, M., Mattalia, A., Montanari, R., Morini, L., Morisco, F., Mousa Hani, S., Muratori, L., Muratori, P., Niro, G. A., Palmieri, V. O., Picciotto, A., Podda, M., Portincasa, P., Ronca, V., Rosina, F., Rossi, S., Sogno, I., Spinzi, G., Spreafico, M., Strazzabosco, M., Tarallo, S., Tarocchi, M., Tiribelli, C., Toniutto, P., Vinci, M., Zuin, M., Ch'Ng, C. 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105 Scopus citations

Kinase genotype analysis of gastric gastrointestinal stromal tumor cytology samples using targeted next-generation sequencing

Gleeson, F. C., Kipp, B. R., Kerr, S. E., Voss, J. S., Graham, R. P., Campion, M. B., Minot, D. M., Tu, Z. J., Klee, E. W., Lazaridis, K. N., Henry, M. R. & Levy, M. J., Jan 1 2015, In : Clinical Gastroenterology and Hepatology. 13, 1, p. 202-206 5 p.

Research output: Contribution to journalArticle

23 Scopus citations

Somatic STK11 and concomitant STK11/KRAS mutational frequency in stage IV lung adenocarcinoma adrenal metastases

Gleeson, F. C., Kipp, B. R., Levy, M. J., Voss, J. S., Campion, M. B., Minot, D. M., Tu, Z. J., Klee, E. W., Lazaridis, K. N. & Kerr, S. E., Mar 30 2015, In : Journal of Thoracic Oncology. 10, 3, p. 531-534 4 p.

Research output: Contribution to journalArticle

6 Scopus citations

The cholangiopathies

Lazaridis, K. N. & La Russo, N. F., Jun 1 2015, In : Mayo Clinic Proceedings. 90, 6, p. 791-800 10 p.

Research output: Contribution to journalArticle

97 Scopus citations
2014

Biochemical response to ursodeoxycholic acid predicts survival in a North American cohort of primary biliary cirrhosis patients

Lammert, C., Juran, B. D., Schlicht, E., Chan, L. L., Atkinson, E. J., de Andrade, M. & Lazaridis, K. N., Oct 7 2014, In : Journal of gastroenterology. 49, 10, p. 1414-1420 7 p.

Research output: Contribution to journalArticle

19 Scopus citations

Environmental factors in primary biliary cirrhosis

Juran, B. D. & Lazaridis, K. N., Aug 2014, In : Seminars in Liver Disease. 34, 3, p. 265-272 8 p.

Research output: Contribution to journalArticle

45 Scopus citations

Implementing individualized medicine into the medical practice

Lazaridis, K. N., MCAllister, T. M., Babovic-Vuksanovic, D., Beck, S. A., Borad, M. J., Bryce, A. H., Chanan-Khan, A. A., Ferber, M. J., Fonseca, R., Johnson, K. J., Klee, E. W., Lindor, N. M., McCormick, J. B., MCWilliams, R. R., Parker, A. S., Riegert-Johnson, D. L., Rohrer Vitek, C. R., Schahl, K. A., Schultz, C., Stewart, K. & 3 others, Then, G. C., Wieben, E. D. & Farrugia, G., Mar 2014, In : American Journal of Medical Genetics, Part C: Seminars in Medical Genetics. 166, 1, p. 15-23 9 p.

Research output: Contribution to journalArticle

40 Scopus citations

Integrated Genomic Characterization Reveals Novel, Therapeutically Relevant Drug Targets in FGFR and EGFR Pathways in Sporadic Intrahepatic Cholangiocarcinoma

Borad, M. J., Champion, M. D., Egan, J. B., Liang, W. S., Fonseca, R., Bryce, A. H., McCullough, A. E., Barrett, M. T., Hunt, K., Patel, M. D., Young, S. W., Collins, J. M., Silva, A. C., Condjella, R. M., Block, M., McWilliams, R. R., Lazaridis, K. N., Klee, E. W., Bible, K. C., Harris, P. & 29 others, Oliver, G. R., Bhavsar, J. D., Nair, A. A., Middha, S., Asmann, Y., Kocher, J. P., Schahl, K., Kipp, B. R., Barr Fritcher, E. G., Baker, A., Aldrich, J., Kurdoglu, A., Izatt, T., Christoforides, A., Cherni, I., Nasser, S., Reiman, R., Phillips, L., McDonald, J., Adkins, J., Mastrian, S. D., Placek, P., Watanabe, A. T., LoBello, J., Han, H., Von Hoff, D., Craig, D. W., Stewart, A. K. & Carpten, J. D., Feb 2014, In : PLoS genetics. 10, 2, e1004135.

Research output: Contribution to journalArticle

174 Scopus citations

Lung cancer adrenal gland metastasis: Optimal fine-needle aspirate and touch preparation smear cellularity characteristics for successful theranostic next-generation sequencing

Gleeson, F. C., Kipp, B. R., Levy, M. J., Voss, J. S., Campion, M. B., Minot, D. M., Tu, Z. J., Klee, E. W., Lazaridis, K. N. & Kerr, S. E., Nov 1 2014, In : Cancer Cytopathology. 122, 11, p. 822-832 11 p.

Research output: Contribution to journalArticle

41 Scopus citations

Novel de novo heterozygous FGFR1 mutation in two siblings with Hartsfield syndrome: A case of gonadal mosaicism

Dhamija, R., Kirmani, S. B., Wang, X., Ferber, M. J., Wieben, E. D., Lazaridis, K. N. & Babovic-Vuksanovic, D., Sep 2014, In : American Journal of Medical Genetics, Part A. 164, 9, p. 2356-2359 4 p.

Research output: Contribution to journalArticle

14 Scopus citations

Reduced coffee consumption among individuals with primary sclerosing cholangitis but not primary biliary cirrhosis

Lammert, C., Juran, B. D., Schlicht, E., Xie, X., Atkinson, E. J., De Andrade, M. & Lazaridis, K. N., Sep 2014, In : Clinical Gastroenterology and Hepatology. 12, 9, p. 1562-1568 7 p.

Research output: Contribution to journalArticle

19 Scopus citations