Konstantinos N Lazaridis, MD, FACP, AGAF

  • 5475 Citations
  • 38 Scopus h-Index
1993 …2019
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Research Output 1993 2019

Article
72 Citations (Scopus)

{A figure is presented}The Utility of Lens Culinaris Agglutinin-Reactive α-Fetoprotein in the Diagnosis of Hepatocellular Carcinoma: Evaluation in a United States Referral Population

Leerapun, A., Suravarapu, S. V., Bida, J. P., Clark, R. J., Sanders, E. L., Mettler, T. A., Stadheim, L. M., Aderca, I., Moser, C. D., Nagorney, D. M., La Russo, N. F., de Groen, P. C., Menon, K. V. N., Lazaridis, K. N., Gores, G. J., Charlton, M. R., Roberts, R. O., Therneau, T. M., Katzmann, J. A. & Roberts, L. R., Mar 2007, In : Clinical Gastroenterology and Hepatology. 5, 3, p. 394-402 9 p.

Research output: Contribution to journalArticle

Fetal Proteins
Hepatocellular Carcinoma
Referral and Consultation
Population
lentil lectin
2 Citations (Scopus)

28-year-old man with renal insufficiency and Jaundice

Lazaridis, K. N. & Kamath, P. S., 1997, In : Mayo Clinic Proceedings. 72, 11, p. 1057-1060 4 p.

Research output: Contribution to journalArticle

Jaundice
Renal Insufficiency
18 Citations (Scopus)

A comprehensive assessment of environmental exposures among 1000 North American patients with primary sclerosing cholangitis, with and without inflammatory bowel disease

Eaton, J. E., Juran, B. D., Atkinson, E. J., Schlicht, E. M., Xie, X., De Andrade, M., Lammert, C. S., Luketic, V. A., Odin, J. A., Koteish, A. A., Kowdley, K. V., Chopra, K. B., Hirschfield, G. M., Chalasani, N. P. & Lazaridis, K. N., May 1 2015, In : Alimentary Pharmacology and Therapeutics. 41, 10, p. 980-990 11 p.

Research output: Contribution to journalArticle

Sclerosing Cholangitis
Environmental Exposure
Inflammatory Bowel Diseases
Urinary Tract Infections
Smoking
53 Citations (Scopus)

A Large Set of Finnish Affected Sibling Pair Families with Type 2 Diabetes Suggests Susceptibility Loci on Chromosomes 6, 11, and 14

Silander, K., Scott, L. J., Valle, T. T., Mohlke, K. L., Stringham, H. M., Wiles, K. R., Duren, W. L., Doheny, K. F., Pugh, E. W., Chines, P., Narisu, N., White, P. P., Fingerlin, T. E., Jackson, A. U., Li, C., Ghosh, S., Magnuson, V. L., Colby, K., Erdos, M. R., Hill, J. E. & 26 others, Hollstein, P., Humphreys, K. M., Kasad, R. A., Lambert, J., Lazaridis, K. N., Lin, G., Morales-Mena, A., Patzkowski, K., Pfahl, C., Porter, R., Rha, D., Segal, L., Suh, Y. D., Tovar, J., Unni, A., Welch, C., Douglas, J. A., Epstein, M. P., Hauser, E. R., Hagopian, W., Buchanan, T. A., Watanabe, R. M., Bergman, R. N., Tuomilehto, J., Collins, F. S. & Boehnke, M., Mar 2004, In : Diabetes. 53, 3, p. 821-829 9 p.

Research output: Contribution to journalArticle

Chromosomes, Human, Pair 14
Chromosomes, Human, Pair 11
Chromosomes, Human, Pair 6
Finland
Type 2 Diabetes Mellitus
98 Citations (Scopus)
Alternative Splicing
Bile Acids and Salts
Sodium
Ileum
Hepatocytes
13 Citations (Scopus)
Gastrointestinal Diseases
Gastroenterology
Genomics
Proteomics
Technology
181 Citations (Scopus)

Analysis of five chronic inflammatory diseases identifies 27 new associations and highlights disease-specific patterns at shared loci

Ellinghaus, D., Jostins, L., Spain, S. L., Cortes, A., Bethune, J., Han, B., Park, Y. R., Raychaudhuri, S., Pouget, J. G., Hübenthal, M., Folseraas, T., Wang, Y., Esko, T., Metspalu, A., Westra, H. J., Franke, L., Pers, T. H., Weersma, R. K., Collij, V., D'Amato, M. & 25 others, Halfvarson, J., Jensen, A. B., Lieb, W., Degenhardt, F., Forstner, A. J., Hofmann, A., Schreiber, S., Mrowietz, U., Juran, B. D., Lazaridis, K. N., Brunak, SØ., Dale, A. M., Trembath, R. C., Weidinger, S., Weichenthal, M., Ellinghaus, E., Elder, J. T., Barker, J. N. W. N., Andreassen, O. A., McGovern, D. P., Karlsen, T. H., Barrett, J. C., Parkes, M., Brown, M. A. & Franke, A., May 1 2016, In : Nature Genetics. 48, 5, p. 510-518 9 p.

Research output: Contribution to journalArticle

Comorbidity
Sclerosing Cholangitis
Chronic Disease
Inflammatory Bowel Diseases
Molecular Pathology
43 Citations (Scopus)

Analysis of transforming growth factor β and other cytokines in autoimmune exocrinopathy (Sjogren's syndrome)

Ogawa, N., Dang, H., Lazaridis, K. N., McGuff, H. S., Aufdemorte, T. B. & Talal, N., 1995, In : Journal of Interferon and Cytokine Research. 15, 9, p. 759-767 9 p.

Research output: Contribution to journalArticle

Sjogren's Syndrome
Transforming Growth Factors
Salivary Glands
Cytokines
Interleukin-10
12 Citations (Scopus)

Applying genomics to the study of complex disease

Juran, B. D. & Lazaridis, K. N., Feb 2007, In : Seminars in Liver Disease. 27, 1, p. 3-12 10 p.

Research output: Contribution to journalArticle

Genomics
Liver Diseases
Gallbladder
Epigenomics
Hepatitis
23 Citations (Scopus)

Association between HLA haplotypes and increased serum levels of IgG4 in patients with primary sclerosing cholangitis

Berntsen, N. L., Klingenberg, O., Juran, B. D., Benito De Valle, M., Lindkvist, B., Lazaridis, K. N., Boberg, K. M., Karlsen, T. H. & Hov, J. R., May 1 2015, In : Gastroenterology. 148, 5, p. 924-927.e2

Research output: Contribution to journalArticle

Sclerosing Cholangitis
Haplotypes
Immunoglobulin G
Serum
Norway
4 Citations (Scopus)

Association between variants in inflammation and cancer-associated genes and risk and survival of cholangiocarcinoma

Chaiteerakij, R., Juran, B. D., Aboelsoud, M. M., Harmsen, W. S., Moser, C. D., Giama, N. H., Allotey, L. K., Mettler, T. A., Baichoo, E., Zhang, X., Therneau, T. M., Lazaridis, K. N. & Roberts, L. R., Oct 1 2015, In : Cancer Medicine. 4, 10, p. 1599-1602 4 p.

Research output: Contribution to journalArticle

Cholangiocarcinoma
Neoplasm Genes
Inflammation
Survival
Single Nucleotide Polymorphism
50 Citations (Scopus)

Association of primary biliary cirrhosis with variants in the CLEC16A, SOCS1, SPIB and SIAE immunomodulatory genes

Hirschfield, G. M., Xie, G., Lu, E., Sun, Y., Juran, B. D., Chellappa, V., Coltescu, C., Mason, A. L., Milkiewicz, P., Myers, R. P., Odin, J. A., Luketic, V. A., Bacon, B., Bodenheimer, H., Liakina, V., Vincent, C., Levy, C., Pillai, S., Lazaridis, K. N., Amos, C. I. & 1 others, Siminovitch, K. A., Jun 2012, In : Genes and Immunity. 13, 4, p. 328-335 8 p.

Research output: Contribution to journalArticle

Acetylesterase
Biliary Liver Cirrhosis
N-Acetylneuraminic Acid
Single Nucleotide Polymorphism
Cytokines

At the end of the beginning

Karlsen, T. H. & Lazaridis, K. N., 2011, In : Seminars in Liver Disease. 31, 2, p. 111-113 3 p.

Research output: Contribution to journalArticle

Human Genome Project
Heredity
Genome-Wide Association Study
Pedigree
Genetic Predisposition to Disease
19 Citations (Scopus)

Biochemical response to ursodeoxycholic acid predicts survival in a North American cohort of primary biliary cirrhosis patients

Lammert, C., Juran, B. D., Schlicht, E., Chan, L. L., Atkinson, E. J., De Andrade, M. & Lazaridis, K. N., Oct 7 2014, In : Journal of Gastroenterology. 49, 10, p. 1414-1420 7 p.

Research output: Contribution to journalArticle

Ursodeoxycholic Acid
Biliary Liver Cirrhosis
Survival
Transplants
Alkaline Phosphatase
33 Citations (Scopus)

Carriage of a tumor necrosis factor polymorphism amplifies the cytotoxic T-lymphocyte antigen 4 attributed risk of primary biliary cirrhosis: Evidence for a gene-gene interaction

Juran, B. D., Atkinson, E. J., Larson, J. J., Schlicht, E. M., Liu, X., Heathcote, E. J., Hirschfield, G. M., Siminovitch, K. A. & Lazaridis, K. N., Jul 2010, In : Hepatology. 52, 1, p. 223-229 7 p.

Research output: Contribution to journalArticle

CTLA-4 Antigen
Biliary Liver Cirrhosis
Tumor Necrosis Factor-alpha
Genes
Odds Ratio
15 Citations (Scopus)

Characterization of endoscopic ultrasound fine-needle aspiration cytology by targeted next-generation sequencing and theranostic potential

Gleeson, F. C., Kipp, B. R., Kerr, S. E., Voss, J. S., Lazaridis, K. N., Katzka, D. A. & Levy, M. J., Jan 1 2015, In : Clinical Gastroenterology and Hepatology. 13, 1, p. 37-41 5 p.

Research output: Contribution to journalArticle

Fine Needle Biopsy
Cell Biology
Neoplasms
High-Throughput Nucleotide Sequencing
Neoplasm Genes
358 Citations (Scopus)

Cholangiocarcinoma

Lazaridis, K. N. & Gores, G. J., May 2005, In : Gastroenterology. 128, 6, p. 1655-1667 13 p.

Research output: Contribution to journalArticle

Bile Duct Neoplasms
Intrahepatic Bile Ducts
Cholangiocarcinoma
1 Citation (Scopus)

Clinical Applications and Utility of a Precision Medicine Approach for Patients With Unexplained Cytopenias

Mangaonkar, A. A., Ferrer, A., Pinto e Vairo, F., Cousin, M. A., Kuisle, R. J., Gangat, N., Hogan, W. J., Litzow, M. R., McAllister, T. M., Klee, E. W., Lazaridis, K. N., Stewart, A. K. & Patnaik, M. M., Jan 1 2019, In : Mayo Clinic proceedings.

Research output: Contribution to journalArticle

Precision Medicine
Exome
Poisons
Hematopoietic Stem Cell Transplantation
Cell Lineage
5 Citations (Scopus)

Clinical characteristics and platelet phenotype in a family with RUNX1 mutated thrombocytopenia

Perez Botero, J., Chen, D., Cousin, M. A., Majerus, J. A., Coon, L. M., Kruisselbrink, T. M., Klee, E. W., Lazaridis, K. N., Pruthi, R. K. & Patnaik, M. M., Dec 8 2016, (Accepted/In press) In : Leukemia and Lymphoma. p. 1-5 5 p.

Research output: Contribution to journalArticle

Thrombocytopenia
Blood Platelets
Phenotype
60 Citations (Scopus)

Clinical epidemiology of primary biliary cirrhosis: Incidence, prevalence, and impact of therapy

Lazaridis, K. N. & Talwalkar, J. A., May 2007, In : Journal of Clinical Gastroenterology. 41, 5, p. 494-500 7 p.

Research output: Contribution to journalArticle

Biliary Liver Cirrhosis
Epidemiology
Incidence
Therapeutics
Liver
10 Citations (Scopus)

Clinical Implementation of Integrated Genomic Profiling in Patients with Advanced Cancers

Borad, M. J., Egan, J. B., Condjella, R. M., Liang, W. S., Fonseca, R., Ritacca, N. R., McCullough, A. E., Barrett, M., Hunt, K. S., Champion, M. D., Patel, M. D., Young, S. W., Silva, A. C., Ho, T. H., Halfdanarson, T. R., Mc Williams, R. R., Lazaridis, K. N., Ramanathan, R. K., Baker, A., Aldrich, J. & 17 others, Kurdoglu, A., Izatt, T., Christoforides, A., Cherni, I., Nasser, S., Reiman, R., Cuyugan, L., McDonald, J., Adkins, J., Mastrian, S. D., Valdez, R., Jaroszewski, D. E., Von Hoff, D. D., Craig, D. W., Stewart, A. K., Carpten, J. D. & Bryce, A. H., 2016, In : Scientific Reports. 6, 1, 25.

Research output: Contribution to journalArticle

Neoplasms
Therapeutics
DNA Fingerprinting
Patient Preference
Pharmaceutical Preparations
17 Citations (Scopus)

Cloning and expression of SLC10A4, a putative organic anion transport protein

Splinter, P. L., Lazaridis, K. N., Dawson, P. A. & La Russo, N. F., Nov 14 2006, In : World Journal of Gastroenterology. 12, 42, p. 6797-6805 9 p.

Research output: Contribution to journalArticle

Organic Anion Transporters
CHO Cells
Organism Cloning
Taurocholic Acid
Tissue Distribution
2 Citations (Scopus)

Cloning of a Human IgM Autoantibody Bearing a Cross-Reactive Idiotype in a λ. Expression Vector: A New Approach to Studying Autoantibodies

Dang, H., Lazaridis, K. N., Talal, N., Fischbach, M. & Sanz, I., Jun 1993, In : Clinical Immunology and Immunopathology. 67, 3, p. 249-256 8 p.

Research output: Contribution to journalArticle

Autoantibodies
Immunoglobulin M
Immunoglobulins
Organism Cloning
Immunoglobulin Fragments
16 Citations (Scopus)

Common genetic variation and haplotypes of the anion exchanger SLC4A2 in primary biliary cirrhosis

Juran, B. D., Atkinson, E. J., Larson, J. J., Schlicht, E. M. & Lazaridis, K. N., Jun 2009, In : American Journal of Gastroenterology. 104, 6, p. 1406-1411 6 p.

Research output: Contribution to journalArticle

Biliary Liver Cirrhosis
Haplotypes
Anions
Single Nucleotide Polymorphism
Antibodies
195 Citations (Scopus)

Dense genotyping of immune-related disease regions identifies nine new risk loci for primary sclerosing cholangitis

Liu, J. Z., Hov, J. R., Folseraas, T., Ellinghaus, E., Rushbrook, S. M., Doncheva, N. T., Andreassen, O. A., Weersma, R. K., Weismüller, T. J., Eksteen, B., Invernizzi, P., Hirschfield, G. M., Gotthardt, D. N., Pares, A., Ellinghaus, D., Shah, T., Juran, B. D., Milkiewicz, P., Rust, C., Schramm, C. & 64 others, Muler, T., Srivastava, B., Dalekos, G., Nöthen, M. M., Herms, S., Winkelmann, J., Mitrovic, M., Braun, F., Ponsioen, C. Y., Croucher, P. J. P., Sterneck, M., Teufel, A., Andrew L Mason, L. M., Saarela, J., Leppa, V., Dorfman, R., Alvaro, D., Floreani, A., Onengut-Gumuscu, S., Rich, S. S., Thompson, W. K., Schork, A. J., Næss, S., Thomsen, I., Mayr, G., König, I. R., Hveem, K., Cleynen, I., Gutierrez-Achury, J., Ricaño-Ponce, I., Van Heel, D., Björnsson, E., Sandford, R. N., Durie, P. R., Melum, E., Vatn, M. H., Silverberg, M. S., Duerr, R. H., Padyukov, L., Brand, S., Sans, M., Annese, V., Achkar, J. P., Boberg, K. M., Marschall, H. U., Chazouillères, O., Bowlus, C. L., Wijmenga, C., Schrumpf, E., Vermeire, S., Albrecht, M., Rioux, J. D., Alexander, G., Bergquist, A., Cho, J., Schreiber, S., Manns, M. P., Färkkilä, M., Dale, A. M., Chapman, R. W., Lazaridis, K. N., Franke, A., Anderson, C. A. & Karlsen, T. H., Jun 2013, In : Nature Genetics. 45, 6, p. 670-675 6 p.

Research output: Contribution to journalArticle

Sclerosing Cholangitis
Immune System Diseases
Inflammatory Bowel Diseases
Population Control
HLA Antigens
10 Citations (Scopus)

Differential expression of cholangiocyte and ileal bile acid transporters following bile acid supplementation and depletion

Kip, N. S., Lazaridis, K. N., Masyuk, A. I., Splinter, P. L., Huebert, R. C. & La Russo, N. F., May 15 2004, In : World Journal of Gastroenterology. 10, 10, p. 1440-1446 7 p.

Research output: Contribution to journalArticle

Taurocholic Acid
Bile Acids and Salts
Cholestyramine Resin
Diet
Intrahepatic Bile Ducts
5 Citations (Scopus)

Dissecting the genetic susceptibility for cholangiocarcinoma in primary sclerosing cholangitis

Lazaridis, K. N., Jan 2008, In : Hepatology. 47, 1, p. 8-10 3 p.

Research output: Contribution to journalArticle

Immunologic Receptors
Bile Duct Neoplasms
Intrahepatic Bile Ducts
Sclerosing Cholangitis
Cholangiocarcinoma
1 Citation (Scopus)

Doublecortin domain containing protein 2 (DCDC2) genetic variants in primary sclerosing cholangitis

Cheung, A. C., Juran, B. D., Moore, R. M., La Russo, N. F. & Lazaridis, K. N., 2017, (Accepted/In press) In : Journal of Hepatology.

Research output: Contribution to journalArticle

Sclerosing Cholangitis
Protein Domains
30 Citations (Scopus)

Duration of inflammatory bowel disease is associated with increased risk of cholangiocarcinoma in patients with primary sclerosing cholangitis and IBD

Gulamhusein, A. F., Eaton, J. E., Tabibian, J. H., Atkinson, E. J., Juran, B. D. & Lazaridis, K. N., May 1 2016, In : American Journal of Gastroenterology. 111, 5, p. 705-711 7 p.

Research output: Contribution to journalArticle

Sclerosing Cholangitis
Cholangiocarcinoma
Inflammatory Bowel Diseases
Colectomy
Proportional Hazards Models
7 Citations (Scopus)
Ursodeoxycholic Acid
Cholangitis
Transplants
Survival
Therapeutics
74 Citations (Scopus)

Efficacy and safety of transarterial radioembolization versus chemoembolization in patients with hepatocellular carcinoma

Moreno-Luna, L. E., Yang, J. D., Sanchez, W., Paz-Fumagalli, R., Harnois, D., Mettler, T. A., Gansen, D. N., De Groen, P. C., Lazaridis, K. N., Narayanan Menon, K. V., La Russo, N. F., Alberts, S. R., Gores, G. J., Fleming, C. J., Slettedahl, S. W., Harmsen, W. S., Therneau, T. M., Wiseman, G. A., Andrews, J. C. & Roberts, L. R., Jun 2013, In : CardioVascular and Interventional Radiology. 36, 3, p. 714-723 10 p.

Research output: Contribution to journalArticle

Hepatocellular Carcinoma
Safety
Fatigue
Fever
Therapeutics
8 Citations (Scopus)

Emerging genes associated with the progression of nonalcoholic fatty liver disease

Koutsari, C. & Lazaridis, K. N., Sep 2010, In : Hepatology. 52, 3, p. 807-810 4 p.

Research output: Contribution to journalArticle

Severity of Illness Index
Fatty Liver
Genetic Predisposition to Disease
Lipase
Single Nucleotide Polymorphism
4 Citations (Scopus)

Emerging pharmacologic therapies for primary sclerosing cholangitis

Cheung, A. C., Lazaridis, K. N., La Russo, N. F. & Gores, G. J., Mar 2 2017, (Accepted/In press) In : Current Opinion in Gastroenterology.

Research output: Contribution to journalArticle

Sclerosing Cholangitis
Immunomodulation
Microbiota
Pharmaceutical Preparations
Liver Transplantation
27 Citations (Scopus)

Endoscopic ultrasound fine-needle aspiration cytology mutation profiling using targeted next-generation sequencing: personalized care for rectal cancer

Gleeson, F. C., Kipp, B. R., Voss, J. S., Campion, M. B., Minot, D. M., Tu, Z. J., Klee, E. W., Sciallis, A. P., Graham, R., Lazaridis, K. N., Henry, M. R. & Levy, M. J., Jun 1 2015, In : American Journal of Clinical Pathology. 143, 6, p. 879-888 10 p.

Research output: Contribution to journalArticle

Rectal Neoplasms
Fine Needle Biopsy
Cell Biology
Mutation
Lymph Nodes
38 Citations (Scopus)

Environmental factors in primary biliary cirrhosis

Juran, B. D. & Lazaridis, K. N., 2014, In : Seminars in Liver Disease. 34, 3, p. 265-272 8 p.

Research output: Contribution to journalArticle

Biliary Liver Cirrhosis
Molecular Mimicry
Autoimmunity
Urinary Tract Infections
Autoimmune Diseases
9 Citations (Scopus)

Epigenetics in the Primary Biliary Cholangitis and Primary Sclerosing Cholangitis

Cheung, A. C., La Russo, N. F., Gores, G. J. & Lazaridis, K. N., May 1 2017, In : Seminars in Liver Disease. 37, 2, p. 159-174 16 p.

Research output: Contribution to journalArticle

Sclerosing Cholangitis
Cholangitis
Epigenomics
Genes
Genome-Wide Association Study
1 Citation (Scopus)

Erratum: Cholangiocarcinoma (Gastroenterology (2005) 128 (1655-1667))

Lazaridis, K. N. & Gores, G. J., Jul 2005, In : Gastroenterology. 129, 1, p. 400 1 p.

Research output: Contribution to journalArticle

Cholangiocarcinoma
Gastroenterology
2 Citations (Scopus)

Examining the increased IgM production and ursodeoxycholic acid treatment in PBC

Lazaridis, K. N. & La Russo, N. F., Feb 2005, In : Gastroenterology. 128, 2, p. 498-500 3 p.

Research output: Contribution to journalArticle

Cholagogues and Choleretics
Immunologic Memory
Ursodeoxycholic Acid
Biliary Liver Cirrhosis
Immunoglobulin M
15 Citations (Scopus)

Experience with precision genomics and tumor board, indicates frequent target identification, but barriers to delivery

Bryce, A. H., Egan, J. B., Borad, M. J., Stewart, A. K., Nowakowski, G. S., Chanan Khan, A. A., Patnaik, M. M., Ansell, S. M., Banck, M. S., Robinson, S., Mansfield, A., Klee, E. W., Oliver, G. R., McCormick, J. B., Huneke, N. E., Tagtow, C. M., Jenkins, R. B., Rumilla, K. M., Kerr, S. E., Kocher, J-P. & 5 others, Beck, S. A., Fernandez-Zapico, M. E., Farrugia, G., Lazaridis, K. N. & Mc Williams, R. R., 2017, In : Oncotarget. 8, 16, p. 27145-27154 10 p.

Research output: Contribution to journalArticle

Genomics
Neoplasms
Precision Medicine
Standard of Care
Therapeutics
136 Citations (Scopus)

Extended analysis of a genome-wide association study in primary sclerosing cholangitis detects multiple novel risk loci

Folseraas, T., Melum, E., Rausch, P., Juran, B. D., Ellinghaus, E., Shiryaev, A., Laerdahl, J. K., Ellinghaus, D., Schramm, C., Weismüller, T. J., Gotthardt, D. N., Hov, J. R., Clausen, O. P., Weersma, R. K., Janse, M., Boberg, K. M., Björnsson, E., Marschall, H. U., Cleynen, I., Rosenstiel, P. & 20 others, Holm, K., Teufel, A., Rust, C., Gieger, C., Wichmann, H. E., Bergquist, A., Ryu, E., Ponsioen, C. Y., Runz, H., Sterneck, M., Vermeire, S., Beuers, U., Wijmenga, C., Schrumpf, E., Manns, M. P., Lazaridis, K. N., Schreiber, S., Baines, J. F., Franke, A. & Karlsen, T. H., Aug 2012, In : Journal of Hepatology. 57, 2, p. 366-375 10 p.

Research output: Contribution to journalArticle

Sclerosing Cholangitis
Genome-Wide Association Study
Single Nucleotide Polymorphism
Chromosomes
Genotype
3 Citations (Scopus)

Frequency of mitogen-activated protein kinase and phosphoinositide 3-kinase signaling pathway pathogenic alterations in EUS-FNA sampled malignant lymph nodes in rectal cancer with theranostic potential

Gleeson, F. C., Kipp, B. R., Voss, J. S., Campion, M. B., Minot, D. M., Tu, Z. J., Klee, E. W., Graham, R., Lazaridis, K. N., Henry, M. R. & Levy, M. J., Sep 1 2015, In : Gastrointestinal Endoscopy. 82, 3, p. 550-556 7 p.

Research output: Contribution to journalArticle

MAP Kinase Kinase 3
Endoscopic Ultrasound-Guided Fine Needle Aspiration
1-Phosphatidylinositol 4-Kinase
Rectal Neoplasms
Lymph Nodes
14 Citations (Scopus)

Genetic association analysis identifies variants associated with disease progression in primary sclerosing cholangitis

Müller, T., Alberts, R., De Vries, E. M. G., Goode, E. C., Jiang, X., Sampaziotis, F., Rombouts, K., Böttcher, K., Folseraas, T., Weismüller, T. J., Mason, A. L., Wang, W., Alexander, G., Alvaro, D., Bergquist, A., Björkström, N. K., Beuers, U., Björnsson, E., Boberg, K. M., Bowlus, C. L. & 54 others, Bragazzi, M. C., Carbone, M., Chazouillères, O., Cheung, A., Dalekos, G., Eaton, J., Eksteen, B., Ellinghaus, D., Färkkilä, M., Festen, E. A. M., Floreani, A., Franceschet, I., Gotthardt, D. N., Hirschfield, G. M., Hoek, B. V., Holm, K., Hohenester, S., Hov, J. R., Imhann, F., Invernizzi, P., Juran, B. D., Lenzen, H., Lieb, W., Liu, J. Z., Marschall, H. U., Marzioni, M., Melum, E., Milkiewicz, P., Pares, A., Rupp, C., Rust, C., Sandford, R. N., Schramm, C., Schreiber, S., Schrumpf, E., Silverberg, M. S., Srivastava, B., Sterneck, M., Teufel, A., Vallier, L., Verheij, J., Vila, A. V., De Vries, B., Zachou, K., Chapman, R. W., Manns, M. P., Pinzani, M., Rushbrook, S. M., Lazaridis, K. N., Franke, A., Anderson, C. A., Karlsen, T. H., Ponsioen, C. Y. & Weersma, R. K., Aug 1 2018, In : Gut. 67, 8, p. 1517-1524 8 p.

Research output: Contribution to journalArticle

Sclerosing Cholangitis
Disease Progression
Liver
Transplants
Survival
17 Citations (Scopus)

Genetic polymorphisms of matrix metalloproteinase 3 in primary sclerosing cholangitis

Juran, B. D., Atkinson, E. J., Schlicht, E. M., Larson, J. J., Ellinghaus, D., Franke, A. & Lazaridis, K. N., Jul 2011, In : Liver International. 31, 6, p. 787-793 7 p.

Research output: Contribution to journalArticle

Matrix Metalloproteinase 3
Sclerosing Cholangitis
Genetic Polymorphisms
Single Nucleotide Polymorphism
Ulcerative Colitis

Genetic polymorphisms of matrix metalloproteinase 3 in primary sclerosing cholangitis.

Juran, B. D., Atkinson, E. J., Schlicht, E. M., Larson, J. J., Ellinghaus, D., Franke, A. & Lazaridis, K. N., Jul 2011, In : Liver international : official journal of the International Association for the Study of the Liver. 31, 6, p. 785-791 7 p.

Research output: Contribution to journalArticle

Matrix Metalloproteinase 3
Sclerosing Cholangitis
Genetic Polymorphisms
Single Nucleotide Polymorphism
Ulcerative Colitis
1 Citation (Scopus)

Genetics and genomics of complex diseases in hepatology: Foreword

Lazaridis, K. N., Feb 2007, In : Seminars in Liver Disease. 27, 1, p. 1-2 2 p.

Research output: Contribution to journalArticle

Gastroenterology
Genomics
21 Citations (Scopus)

Genetics and Genomics of Primary Biliary Cirrhosis

Juran, B. D. & Lazaridis, K. N., May 2008, In : Clinics in Liver Disease. 12, 2, p. 349-365 17 p.

Research output: Contribution to journalArticle

Biliary Liver Cirrhosis
Genomics
Genes
Genetic Predisposition to Disease
Haplotypes
7 Citations (Scopus)

Genetics of Hepatobiliary Diseases

Juran, B. D. & Lazaridis, K. N., May 2006, In : Clinical Gastroenterology and Hepatology. 4, 5, p. 548-557 10 p.

Research output: Contribution to journalArticle

Inborn Genetic Diseases
Liver Diseases
HapMap Project
Alcoholic Liver Diseases
Medical Genetics
159 Citations (Scopus)

Genome-wide association analysis in primary sclerosing cholangitis identifies two non-HLA susceptibility loci

Melum, E., Franke, A., Schramm, C., Weismüller, T. J., Gotthardt, D. N., Offner, F. A., Juran, B. D., Laerdahl, J. K., Labi, V., Bjürnsson, E., Weersma, R. K., Henckaerts, L., Teufel, A., Rust, C., Ellinghaus, E., Balschun, T., Boberg, K. M., Ellinghaus, D., Bergquist, A., Sauer, P. & 23 others, Ryu, E., Hov, J. R., Wedemeyer, J., Lindkvist, B., Wittig, M., Porte, R. J., Holm, K., Gieger, C., Wichmann, H. E., Stokkers, P., Ponsioen, C. Y., Runz, H., Stiehl, A., Wijmenga, C., Sterneck, M., Vermeire, S., Beuers, U., Villunger, A., Schrumpf, E., Lazaridis, K. N., Manns, M. P., Schreiber, S. & Karlsen, T. H., Jan 2011, In : Nature Genetics. 43, 1, p. 17-19 3 p.

Research output: Contribution to journalArticle

Sclerosing Cholangitis
Genome-Wide Association Study
Bile Duct Diseases
Inflammatory Bowel Diseases
Single Nucleotide Polymorphism
27 Citations (Scopus)

Genome-Wide Association Studies in Primary Biliary Cirrhosis

Gulamhusein, A. F., Juran, B. D. & Lazaridis, K. N., Nov 1 2015, In : Seminars in Liver Disease. 35, 4, p. 392-401 10 p.

Research output: Contribution to journalArticle

Biliary Liver Cirrhosis
Genome-Wide Association Study
HLA Antigens
Inborn Genetic Diseases
Linkage Disequilibrium
52 Citations (Scopus)

Genome-wide association study of primary sclerosing cholangitis identifies new risk loci and quantifies the genetic relationship with inflammatory bowel disease

The UK-PSC Consortium, The International IBD Genetics Consortium & The International PSC Study Group, Dec 19 2016, (Accepted/In press) In : Nature Genetics.

Research output: Contribution to journalArticle

Sclerosing Cholangitis
Genetic Loci
Genome-Wide Association Study
Inflammatory Bowel Diseases
Ulcerative Colitis