Konstantinos N Lazaridis, MD, FACP, AGAF

  • 5475 Citations
  • 38 Scopus h-Index
1993 …2019
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Research Output 1993 2019

2014
19 Citations (Scopus)

Biochemical response to ursodeoxycholic acid predicts survival in a North American cohort of primary biliary cirrhosis patients

Lammert, C., Juran, B. D., Schlicht, E., Chan, L. L., Atkinson, E. J., De Andrade, M. & Lazaridis, K. N., Oct 7 2014, In : Journal of Gastroenterology. 49, 10, p. 1414-1420 7 p.

Research output: Contribution to journalArticle

Ursodeoxycholic Acid
Biliary Liver Cirrhosis
Survival
Transplants
Alkaline Phosphatase
38 Citations (Scopus)

Environmental factors in primary biliary cirrhosis

Juran, B. D. & Lazaridis, K. N., 2014, In : Seminars in Liver Disease. 34, 3, p. 265-272 8 p.

Research output: Contribution to journalArticle

Biliary Liver Cirrhosis
Molecular Mimicry
Autoimmunity
Urinary Tract Infections
Autoimmune Diseases
10 Citations (Scopus)
Incidental Findings
Medical Genetics
Medicine
40 Citations (Scopus)

Implementing individualized medicine into the medical practice

Lazaridis, K. N., MCAllister, T. M., Babovic-Vuksanovic, D., Beck, S. A., Borad, M. J., Bryce, A. H., Chanan Khan, A. A., Ferber, M. J., Fonseca, R., Johnson, K. J., Klee, E. W., Lindor, N. M., MCCormick, J. B., Mc Williams, R. R., Parker, A., Riegert-Johnson, D. L., Rohrer Vitek, C. R., Schahl, K. A., Schultz, C., Stewart, A. K. & 3 others, Then, G. C., Wieben, E. D. & Farrugia, G., 2014, In : American Journal of Medical Genetics, Part C: Seminars in Medical Genetics. 166, 1, p. 15-23 9 p.

Research output: Contribution to journalArticle

Precision Medicine
Medicine
Patient Care
Exome
Workflow
162 Citations (Scopus)

Integrated Genomic Characterization Reveals Novel, Therapeutically Relevant Drug Targets in FGFR and EGFR Pathways in Sporadic Intrahepatic Cholangiocarcinoma

Borad, M. J., Champion, M. D., Egan, J. B., Liang, W. S., Fonseca, R., Bryce, A. H., McCullough, A. E., Barrett, M., Hunt, K., Patel, M. D., Young, S. W., Collins, J. M., Silva, A. C., Condjella, R. M., Block, M. S., Mc Williams, R. R., Lazaridis, K. N., Klee, E. W., Bible, K. C., Harris, P. & 29 others, Oliver, G. R., Bhavsar, J. D., Nair, A. A., Middha, S., Asmann, Y., Kocher, J-P., Schahl, K., Kipp, B. R., Barr Fritcher, E. G., Baker, A., Aldrich, J., Kurdoglu, A., Izatt, T., Christoforides, A., Cherni, I., Nasser, S., Reiman, R., Phillips, L., McDonald, J., Adkins, J., Mastrian, S. D., Placek, P., Watanabe, A. T., LoBello, J., Han, H., Von Hoff, D., Craig, D. W., Stewart, A. K. & Carpten, J. D., Feb 2014, In : PLoS Genetics. 10, 2, e1004135.

Research output: Contribution to journalArticle

Cholangiocarcinoma
tumor
genomics
drug
inhibitor
37 Citations (Scopus)

Lung cancer adrenal gland metastasis: Optimal fine-needle aspirate and touch preparation smear cellularity characteristics for successful theranostic next-generation sequencing

Gleeson, F. C., Kipp, B. R., Levy, M. J., Voss, J. S., Campion, M. B., Minot, D. M., Tu, Z. J., Klee, E. W., Lazaridis, K. N. & Kerr, S. E., Nov 1 2014, In : Cancer cytopathology. 122, 11, p. 822-832 11 p.

Research output: Contribution to journalArticle

Adrenal Gland Neoplasms
Touch
Needles
Lung Neoplasms
Neoplasm Metastasis
13 Citations (Scopus)

Novel de novo heterozygous FGFR1 mutation in two siblings with Hartsfield syndrome: A case of gonadal mosaicism

Dhamija, R., Kirmani, S., Wang, X., Ferber, M. J., Wieben, E. D., Lazaridis, K. N. & Babovic-Vuksanovic, D., 2014, In : American Journal of Medical Genetics, Part A. 164, 9, p. 2356-2359 4 p.

Research output: Contribution to journalArticle

Fibroblast Growth Factor 1
Mosaicism
Siblings
Mutation
Parents
17 Citations (Scopus)

Reduced coffee consumption among individuals with primary sclerosing cholangitis but not primary biliary cirrhosis

Lammert, C., Juran, B. D., Schlicht, E., Xie, X., Atkinson, E. J., De Andrade, M. & Lazaridis, K. N., 2014, In : Clinical Gastroenterology and Hepatology. 12, 9, p. 1562-1568 7 p.

Research output: Contribution to journalArticle

Sclerosing Cholangitis
Biliary Liver Cirrhosis
Coffee
Drinking
Nonparametric Statistics
18 Citations (Scopus)

Small duct primary sclerosing cholangitis without inflammatory bowel disease is genetically different from large duct disease

Næss, S., Björnsson, E., Anmarkrud, J. A., Mamari, S. A., Juran, B. D., Lazaridis, K. N., Chapman, R., Bergquist, A., Melum, E., Marsh, S. G. E., Schrumpf, E., Lie, B. A., Boberg, K. M., Karlsen, T. H. & Hov, J. R., Nov 1 2014, In : Liver International. 34, 10, p. 1488-1495 8 p.

Research output: Contribution to journalArticle

Sclerosing Cholangitis
Inflammatory Bowel Diseases
HLA Antigens
Bile Duct Diseases
2013
195 Citations (Scopus)

Dense genotyping of immune-related disease regions identifies nine new risk loci for primary sclerosing cholangitis

Liu, J. Z., Hov, J. R., Folseraas, T., Ellinghaus, E., Rushbrook, S. M., Doncheva, N. T., Andreassen, O. A., Weersma, R. K., Weismüller, T. J., Eksteen, B., Invernizzi, P., Hirschfield, G. M., Gotthardt, D. N., Pares, A., Ellinghaus, D., Shah, T., Juran, B. D., Milkiewicz, P., Rust, C., Schramm, C. & 64 others, Muler, T., Srivastava, B., Dalekos, G., Nöthen, M. M., Herms, S., Winkelmann, J., Mitrovic, M., Braun, F., Ponsioen, C. Y., Croucher, P. J. P., Sterneck, M., Teufel, A., Andrew L Mason, L. M., Saarela, J., Leppa, V., Dorfman, R., Alvaro, D., Floreani, A., Onengut-Gumuscu, S., Rich, S. S., Thompson, W. K., Schork, A. J., Næss, S., Thomsen, I., Mayr, G., König, I. R., Hveem, K., Cleynen, I., Gutierrez-Achury, J., Ricaño-Ponce, I., Van Heel, D., Björnsson, E., Sandford, R. N., Durie, P. R., Melum, E., Vatn, M. H., Silverberg, M. S., Duerr, R. H., Padyukov, L., Brand, S., Sans, M., Annese, V., Achkar, J. P., Boberg, K. M., Marschall, H. U., Chazouillères, O., Bowlus, C. L., Wijmenga, C., Schrumpf, E., Vermeire, S., Albrecht, M., Rioux, J. D., Alexander, G., Bergquist, A., Cho, J., Schreiber, S., Manns, M. P., Färkkilä, M., Dale, A. M., Chapman, R. W., Lazaridis, K. N., Franke, A., Anderson, C. A. & Karlsen, T. H., Jun 2013, In : Nature Genetics. 45, 6, p. 670-675 6 p.

Research output: Contribution to journalArticle

Sclerosing Cholangitis
Immune System Diseases
Inflammatory Bowel Diseases
Population Control
HLA Antigens
74 Citations (Scopus)

Efficacy and safety of transarterial radioembolization versus chemoembolization in patients with hepatocellular carcinoma

Moreno-Luna, L. E., Yang, J. D., Sanchez, W., Paz-Fumagalli, R., Harnois, D., Mettler, T. A., Gansen, D. N., De Groen, P. C., Lazaridis, K. N., Narayanan Menon, K. V., La Russo, N. F., Alberts, S. R., Gores, G. J., Fleming, C. J., Slettedahl, S. W., Harmsen, W. S., Therneau, T. M., Wiseman, G. A., Andrews, J. C. & Roberts, L. R., Jun 2013, In : CardioVascular and Interventional Radiology. 36, 3, p. 714-723 10 p.

Research output: Contribution to journalArticle

Hepatocellular Carcinoma
Safety
Fatigue
Fever
Therapeutics
196 Citations (Scopus)

Pathogenesis of primary sclerosing cholangitis and advances in diagnosis and management

Eaton, J. E., Talwalkar, J. A., Lazaridis, K. N., Gores, G. J. & Lindor, K. D., Sep 2013, In : Gastroenterology. 145, 3, p. 521-536 16 p.

Research output: Contribution to journalArticle

Sclerosing Cholangitis
Biliary Tract
Fibrosis
Inflammation
Cholestasis
22 Citations (Scopus)

Questionnaire based assessment of risk factors for primary biliary cirrhosis

Lammert, C., Nguyen, D. L., Juran, B. D., Schlicht, E., Larson, J. J., Atkinson, E. J. & Lazaridis, K. N., Jul 2013, In : Digestive and Liver Disease. 45, 7, p. 589-594 6 p.

Research output: Contribution to journalArticle

Biliary Liver Cirrhosis
Urinary Tract Infections
Gene-Environment Interaction
Sex Education
Molecular Epidemiology
88 Citations (Scopus)

The genetics of complex cholestatic disorders

Hirschfield, G. M., Chapman, R. W., Karlsen, T. H., Lammert, F., Lazaridis, K. N. & Mason, A. L., Jun 2013, In : Gastroenterology. 144, 7, p. 1357-1374 18 p.

Research output: Contribution to journalArticle

Sclerosing Cholangitis
Biliary Liver Cirrhosis
Genes
Gallstones
Liver Diseases
2012
50 Citations (Scopus)

Association of primary biliary cirrhosis with variants in the CLEC16A, SOCS1, SPIB and SIAE immunomodulatory genes

Hirschfield, G. M., Xie, G., Lu, E., Sun, Y., Juran, B. D., Chellappa, V., Coltescu, C., Mason, A. L., Milkiewicz, P., Myers, R. P., Odin, J. A., Luketic, V. A., Bacon, B., Bodenheimer, H., Liakina, V., Vincent, C., Levy, C., Pillai, S., Lazaridis, K. N., Amos, C. I. & 1 others, Siminovitch, K. A., Jun 2012, In : Genes and Immunity. 13, 4, p. 328-335 8 p.

Research output: Contribution to journalArticle

Acetylesterase
Biliary Liver Cirrhosis
N-Acetylneuraminic Acid
Single Nucleotide Polymorphism
Cytokines
2 Citations (Scopus)

Cholangiocarcinoma

Lazaridis, K. N. & Gores, G. J., Apr 16 2012, Textbook of Clinical Gastroenterology and Hepatology: Second Edition. Wiley-Blackwell, p. 580-585 6 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Cholangiocarcinoma
Sclerosing Cholangitis
Bile Ducts
Causality
Liver Transplantation
1 Citation (Scopus)

Cholangiocarcinoma

Lazaridis, K. N. & Gores, G. J., 2012, Zakim and Boyer's Hepatology. Elsevier Inc., p. 1032-1044 13 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Cholangiocarcinoma
136 Citations (Scopus)

Extended analysis of a genome-wide association study in primary sclerosing cholangitis detects multiple novel risk loci

Folseraas, T., Melum, E., Rausch, P., Juran, B. D., Ellinghaus, E., Shiryaev, A., Laerdahl, J. K., Ellinghaus, D., Schramm, C., Weismüller, T. J., Gotthardt, D. N., Hov, J. R., Clausen, O. P., Weersma, R. K., Janse, M., Boberg, K. M., Björnsson, E., Marschall, H. U., Cleynen, I., Rosenstiel, P. & 20 others, Holm, K., Teufel, A., Rust, C., Gieger, C., Wichmann, H. E., Bergquist, A., Ryu, E., Ponsioen, C. Y., Runz, H., Sterneck, M., Vermeire, S., Beuers, U., Wijmenga, C., Schrumpf, E., Manns, M. P., Lazaridis, K. N., Schreiber, S., Baines, J. F., Franke, A. & Karlsen, T. H., Aug 2012, In : Journal of Hepatology. 57, 2, p. 366-375 10 p.

Research output: Contribution to journalArticle

Sclerosing Cholangitis
Genome-Wide Association Study
Single Nucleotide Polymorphism
Chromosomes
Genotype
93 Citations (Scopus)

Immunochip analyses identify a novel risk locus for primary biliary cirrhosis at 13q14, multiple independent associations at four established risk loci and epistasis between 1p31 and 7q32 risk Variants

Juran, B. D., Hirschfield, G. M., Invernizzi, P., Atkinson, E. J., Li, Y., Xie, G., Kosoy, R., Ransom, M., Sun, Y., Bianchi, I., Schlicht, E. M., Lleo, A., Coltescu, C., Bernuzzi, F., Podda, M., Lammert, C., Shigeta, R., Chan, L. L., Balschun, T., Marconi, M. & 21 others, Cusi, D., Heathcote, E. J., Mason, A. L., Myers, R. P., Milkiewicz, P., Odin, J. A., Luketic, V. A., Bacon, B. R., Bodenheimer, H. C., Liakina, V., Vincent, C., Levy, C., Franke, A., Gregersen, P. K., Bossa, F., Eric Gershwin, M., De Andrade, M., Amos, C. I., Lazaridis, K. N., Seldin, M. F. & Siminovitch, K. A., Dec 2012, In : Human Molecular Genetics. 21, 23, p. 5209-5221 13 p., dds359.

Research output: Contribution to journalArticle

Biliary Liver Cirrhosis
Haplotypes
Single Nucleotide Polymorphism
Alleles
Genotype
1 Citation (Scopus)

Primary sclerosing cholangitis

Nguyen, D. L., La Russo, N. F. & Lazaridis, K. N., 2012, Blumgart's Surgery of the Liver, Biliary Tract, and Pancreas. Elsevier Inc., Vol. 1. p. 603-614 12 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Sclerosing Cholangitis
2011

At the end of the beginning

Karlsen, T. H. & Lazaridis, K. N., 2011, In : Seminars in Liver Disease. 31, 2, p. 111-113 3 p.

Research output: Contribution to journalArticle

Human Genome Project
Heredity
Genome-Wide Association Study
Pedigree
Genetic Predisposition to Disease
17 Citations (Scopus)

Genetic polymorphisms of matrix metalloproteinase 3 in primary sclerosing cholangitis

Juran, B. D., Atkinson, E. J., Schlicht, E. M., Larson, J. J., Ellinghaus, D., Franke, A. & Lazaridis, K. N., Jul 2011, In : Liver International. 31, 6, p. 787-793 7 p.

Research output: Contribution to journalArticle

Matrix Metalloproteinase 3
Sclerosing Cholangitis
Genetic Polymorphisms
Single Nucleotide Polymorphism
Ulcerative Colitis

Genetic polymorphisms of matrix metalloproteinase 3 in primary sclerosing cholangitis.

Juran, B. D., Atkinson, E. J., Schlicht, E. M., Larson, J. J., Ellinghaus, D., Franke, A. & Lazaridis, K. N., Jul 2011, In : Liver international : official journal of the International Association for the Study of the Liver. 31, 6, p. 785-791 7 p.

Research output: Contribution to journalArticle

Matrix Metalloproteinase 3
Sclerosing Cholangitis
Genetic Polymorphisms
Single Nucleotide Polymorphism
Ulcerative Colitis
159 Citations (Scopus)

Genome-wide association analysis in primary sclerosing cholangitis identifies two non-HLA susceptibility loci

Melum, E., Franke, A., Schramm, C., Weismüller, T. J., Gotthardt, D. N., Offner, F. A., Juran, B. D., Laerdahl, J. K., Labi, V., Bjürnsson, E., Weersma, R. K., Henckaerts, L., Teufel, A., Rust, C., Ellinghaus, E., Balschun, T., Boberg, K. M., Ellinghaus, D., Bergquist, A., Sauer, P. & 23 others, Ryu, E., Hov, J. R., Wedemeyer, J., Lindkvist, B., Wittig, M., Porte, R. J., Holm, K., Gieger, C., Wichmann, H. E., Stokkers, P., Ponsioen, C. Y., Runz, H., Stiehl, A., Wijmenga, C., Sterneck, M., Vermeire, S., Beuers, U., Villunger, A., Schrumpf, E., Lazaridis, K. N., Manns, M. P., Schreiber, S. & Karlsen, T. H., Jan 2011, In : Nature Genetics. 43, 1, p. 17-19 3 p.

Research output: Contribution to journalArticle

Sclerosing Cholangitis
Genome-Wide Association Study
Bile Duct Diseases
Inflammatory Bowel Diseases
Single Nucleotide Polymorphism
30 Citations (Scopus)

Genomics in the post-GWAS era

Juran, B. D. & Lazaridis, K. N., 2011, In : Seminars in Liver Disease. 31, 2, p. 215-222 8 p.

Research output: Contribution to journalArticle

Genome-Wide Association Study
Genomics
Medicine
Genome

Primary Sclerosing Cholangitis

Nguyen, D. L., La Russo, N. F. & Lazaridis, K. N., Oct 31 2011, Schiff's Diseases of the Liver. Wiley-Blackwell, p. 475-489 15 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Sclerosing Cholangitis
Magnetic Resonance Cholangiopancreatography
Cholangiocarcinoma
Biliary Liver Cirrhosis
Endoscopic Retrograde Cholangiopancreatography

Ulcerative colitis and an abnormal cholangiogram

Nguyen, D. L. & Lazaridis, K. N., May 2011, In : Cleveland Clinic Journal of Medicine. 78, 5, p. 306-311 6 p.

Research output: Contribution to journalArticle

Cholagogues and Choleretics
Magnetic Resonance Cholangiopancreatography
Ursodeoxycholic Acid
Sclerosing Cholangitis
Endoscopic Retrograde Cholangiopancreatography
2010
33 Citations (Scopus)

Carriage of a tumor necrosis factor polymorphism amplifies the cytotoxic T-lymphocyte antigen 4 attributed risk of primary biliary cirrhosis: Evidence for a gene-gene interaction

Juran, B. D., Atkinson, E. J., Larson, J. J., Schlicht, E. M., Liu, X., Heathcote, E. J., Hirschfield, G. M., Siminovitch, K. A. & Lazaridis, K. N., Jul 2010, In : Hepatology. 52, 1, p. 223-229 7 p.

Research output: Contribution to journalArticle

CTLA-4 Antigen
Biliary Liver Cirrhosis
Tumor Necrosis Factor-alpha
Genes
Odds Ratio
8 Citations (Scopus)

Emerging genes associated with the progression of nonalcoholic fatty liver disease

Koutsari, C. & Lazaridis, K. N., Sep 2010, In : Hepatology. 52, 3, p. 807-810 4 p.

Research output: Contribution to journalArticle

Severity of Illness Index
Fatty Liver
Genetic Predisposition to Disease
Lipase
Single Nucleotide Polymorphism

Immunology of the Liver and Mechanisms of Inflammation

Lazaridis, K. N., Aug 31 2010, Practical Gastroenterology and Hepatology: Liver and Biliary Disease. Wiley-Blackwell, p. 17-22 6 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Allergy and Immunology
Inflammation
Liver
Autoimmune Hepatitis
Sclerosing Cholangitis
27 Citations (Scopus)

Primary biliary cirrhosis

Nguyen, D. L., Juran, B. D. & Lazaridis, K. N., Oct 2010, In : Best Practice and Research: Clinical Gastroenterology. 24, 5, p. 647-654 8 p.

Research output: Contribution to journalArticle

Biliary Liver Cirrhosis
Ursodeoxycholic Acid
Liver Diseases
Environmental Exposure
Liver Transplantation
27 Citations (Scopus)

Update on the genetics and genomics of PBC

Juran, B. D. & Lazaridis, K. N., Nov 2010, In : Journal of Autoimmunity. 35, 3, p. 181-187 7 p.

Research output: Contribution to journalArticle

Genomics
Genome
Aptitude
Genome-Wide Association Study
Genetic Predisposition to Disease
157 Citations (Scopus)

Variants at IRF5-TNPO3, 17q12-21 and MMEL1 are associated with primary biliary cirrhosis

Hirschfield, G. M., Liu, X., Han, Y., Gorlov, I. P., Lu, Y., Xu, C., Lu, Y., Chen, W., Juran, B. D., Coltescu, C., Mason, A. L., Milkiewicz, P., Myers, R. P., Odin, J. A., Luketic, V. A., Speiciene, D., Vincent, C., Levy, C., Gregersen, P. K., Zhang, J. & 4 others, Heathcote, E. J., Lazaridis, K. N., Amos, C. I. & Siminovitch, K. A., Aug 2010, In : Nature Genetics. 42, 8, p. 655-657 3 p.

Research output: Contribution to journalArticle

Biliary Liver Cirrhosis
Genome-Wide Association Study
Genome
Datasets
2009
16 Citations (Scopus)

Common genetic variation and haplotypes of the anion exchanger SLC4A2 in primary biliary cirrhosis

Juran, B. D., Atkinson, E. J., Larson, J. J., Schlicht, E. M. & Lazaridis, K. N., Jun 2009, In : American Journal of Gastroenterology. 104, 6, p. 1406-1411 6 p.

Research output: Contribution to journalArticle

Biliary Liver Cirrhosis
Haplotypes
Anions
Single Nucleotide Polymorphism
Antibodies
436 Citations (Scopus)

Primary biliary cirrhosis associated with HLA, IL12A, and IL12RB2 variants

Hirschfield, G. M., Liu, X., Xu, C., Lu, Y., Xie, G., Lu, Y., Gu, X., Walker, E. J., Jing, K., Juran, B. D., Mason, A. L., Myers, R. P., Peltekian, K. M., Ghent, C. N., Coltescu, C., Atkinson, E. J., Heathcote, E. J., Lazaridis, K. N., Amos, C. I. & Siminovitch, K. A., Jun 11 2009, In : New England Journal of Medicine. 360, 24, p. 2544-2555 12 p.

Research output: Contribution to journalArticle

Biliary Liver Cirrhosis
Single Nucleotide Polymorphism
Odds Ratio
Interleukin-12
STAT4 Transcription Factor
2008
5 Citations (Scopus)

Dissecting the genetic susceptibility for cholangiocarcinoma in primary sclerosing cholangitis

Lazaridis, K. N., Jan 2008, In : Hepatology. 47, 1, p. 8-10 3 p.

Research output: Contribution to journalArticle

Immunologic Receptors
Bile Duct Neoplasms
Intrahepatic Bile Ducts
Sclerosing Cholangitis
Cholangiocarcinoma
21 Citations (Scopus)

Genetics and Genomics of Primary Biliary Cirrhosis

Juran, B. D. & Lazaridis, K. N., May 2008, In : Clinics in Liver Disease. 12, 2, p. 349-365 17 p.

Research output: Contribution to journalArticle

Biliary Liver Cirrhosis
Genomics
Genes
Genetic Predisposition to Disease
Haplotypes
42 Citations (Scopus)

Interacting alleles of the coinhibitory immunoreceptor genes cytotoxic T-lymphocyte antigen 4 and programmed cell-death 1 influence risk and features of primary biliary cirrhosis

Juran, B. D., Atkinson, E. J., Schlicht, E. M., Fridley, B. L., Petersen, G. M. & Lazaridis, K. N., Feb 2008, In : Hepatology. 47, 2, p. 563-570 8 p.

Research output: Contribution to journalArticle

CTLA-4 Antigen
Biliary Liver Cirrhosis
Cell Death
Alleles
Single Nucleotide Polymorphism
47 Citations (Scopus)

Primary Biliary Cirrhosis Is Associated With a Genetic Variant in the 3′ Flanking Region of the CTLA4 Gene

Juran, B. D., Atkinson, E. J., Schlicht, E. M., Fridley, B. L. & Lazaridis, K. N., Oct 2008, In : Gastroenterology. 135, 4, p. 1200-1206 7 p.

Research output: Contribution to journalArticle

CTLA-4 Antigen
3' Flanking Region
Biliary Liver Cirrhosis
Genes
Single Nucleotide Polymorphism

Sclerosing Cholangitis

Lazaridis, K. N. & La Russo, N. F., Apr 15 2008, Textbook of Hepatology: From Basic Science to Clinical Practice, Third Edition. Blackwell Publishing Ltd, p. 1103-1110 8 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Choledocholithiasis
Sclerosing Cholangitis
12 Citations (Scopus)

Sclerosing cholangitis epidemiology and etiology

Lazaridis, K. N., Mar 2008, In : Journal of Gastrointestinal Surgery. 12, 3, p. 417-419 3 p.

Research output: Contribution to journalArticle

Sclerosing Cholangitis
Epidemiology
Biliary Tract
Chronic Disease
2007
72 Citations (Scopus)

{A figure is presented}The Utility of Lens Culinaris Agglutinin-Reactive α-Fetoprotein in the Diagnosis of Hepatocellular Carcinoma: Evaluation in a United States Referral Population

Leerapun, A., Suravarapu, S. V., Bida, J. P., Clark, R. J., Sanders, E. L., Mettler, T. A., Stadheim, L. M., Aderca, I., Moser, C. D., Nagorney, D. M., La Russo, N. F., de Groen, P. C., Menon, K. V. N., Lazaridis, K. N., Gores, G. J., Charlton, M. R., Roberts, R. O., Therneau, T. M., Katzmann, J. A. & Roberts, L. R., Mar 2007, In : Clinical Gastroenterology and Hepatology. 5, 3, p. 394-402 9 p.

Research output: Contribution to journalArticle

Fetal Proteins
Hepatocellular Carcinoma
Referral and Consultation
Population
lentil lectin
12 Citations (Scopus)

Applying genomics to the study of complex disease

Juran, B. D. & Lazaridis, K. N., Feb 2007, In : Seminars in Liver Disease. 27, 1, p. 3-12 10 p.

Research output: Contribution to journalArticle

Genomics
Liver Diseases
Gallbladder
Epigenomics
Hepatitis
60 Citations (Scopus)

Clinical epidemiology of primary biliary cirrhosis: Incidence, prevalence, and impact of therapy

Lazaridis, K. N. & Talwalkar, J. A., May 2007, In : Journal of Clinical Gastroenterology. 41, 5, p. 494-500 7 p.

Research output: Contribution to journalArticle

Biliary Liver Cirrhosis
Epidemiology
Incidence
Therapeutics
Liver
1 Citation (Scopus)

Genetics and genomics of complex diseases in hepatology: Foreword

Lazaridis, K. N., Feb 2007, In : Seminars in Liver Disease. 27, 1, p. 1-2 2 p.

Research output: Contribution to journalArticle

Gastroenterology
Genomics
51 Citations (Scopus)

Hypothyroidism: A Possible Risk Factor for Liver Cancer in Patients With No Known Underlying Cause of Liver Disease

Reddy, A., Dash, C., Leerapun, A., Mettler, T. A., Stadheim, L. M., Lazaridis, K. N., Roberts, R. O. & Roberts, L. R., Jan 2007, In : Clinical Gastroenterology and Hepatology. 5, 1, p. 118-123 6 p.

Research output: Contribution to journalArticle

Liver Neoplasms
Hypothyroidism
Liver Diseases
Hepatocellular Carcinoma
Alcoholic Liver Diseases
100 Citations (Scopus)

Increased prevalence of antimitochondrial antibodies in first-degree relatives of patients with primary biliary cirrhosis

Lazaridis, K. N., Juran, B. D., Boe, G. M., Slusser, J. P., De Andrade, M., Homburger, H. A., Ghosh, K., Dickson, E. R., Lindor, K. D. & Petersen, G. M., Sep 2007, In : Hepatology. 46, 3, p. 785-792 8 p.

Research output: Contribution to journalArticle

Biliary Liver Cirrhosis
Antibodies
Cholestasis
Pedigree
Nuclear Family
1 Citation (Scopus)

Our New President-Nicholas F. LaRusso, MD

Lazaridis, K. N. & Gores, G. J., May 2007, In : Gastroenterology. 132, 5, p. 2005-2011 7 p.

Research output: Contribution to journalArticle

Governing Board
Mentors
Administrative Personnel
Physicians
2006
1 Citation (Scopus)

Cholangiocarcinoma

Lazaridis, K. N. & Gores, G. J., 2006, Zakim and Boyer's Hepatology. Elsevier Inc., p. 1133-1146 14 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Cholangiocarcinoma
17 Citations (Scopus)

Cloning and expression of SLC10A4, a putative organic anion transport protein

Splinter, P. L., Lazaridis, K. N., Dawson, P. A. & La Russo, N. F., Nov 14 2006, In : World Journal of Gastroenterology. 12, 42, p. 6797-6805 9 p.

Research output: Contribution to journalArticle

Organic Anion Transporters
CHO Cells
Organism Cloning
Taurocholic Acid
Tissue Distribution