Konstantinos N Lazaridis, MD, FACP, AGAF

  • 5475 Citations
  • 38 Scopus h-Index
1993 …2019
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Research Output 1993 2019

2006
7 Citations (Scopus)

Genetics of Hepatobiliary Diseases

Juran, B. D. & Lazaridis, K. N., May 2006, In : Clinical Gastroenterology and Hepatology. 4, 5, p. 548-557 10 p.

Research output: Contribution to journalArticle

Inborn Genetic Diseases
Liver Diseases
HapMap Project
Alcoholic Liver Diseases
Medical Genetics
23 Citations (Scopus)

Genomics and complex liver disease: Challenges and opportunities

Juran, B. D. & Lazaridis, K. N., Dec 2006, In : Hepatology. 44, 6, p. 1380-1390 11 p.

Research output: Contribution to journalArticle

Genomics
Liver Diseases
Genetic Predisposition to Disease
HapMap Project
Aptitude
3 Citations (Scopus)

Polluting the pathogenesis of primary biliary cirrhosis

Talwalkar, J. A. & Lazaridis, K. N., Mar 2006, In : Hepatology. 43, 3, p. 398-400 3 p.

Research output: Contribution to journalArticle

Environmental Illness
Hazardous Waste
Biliary Liver Cirrhosis
Environmental Exposure
England

Primary Sclerosing Cholangitis

Lazaridis, K. N. & La Russo, N. F., 2006, Therapy of Digestive Disorders. Elsevier Inc., p. 409-415 7 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Sclerosing Cholangitis
95 Citations (Scopus)

Primary sclerosing cholangitis and cholangiocarcinoma

Lazaridis, K. N. & Gores, G. J., Feb 2006, In : Seminars in Liver Disease. 26, 1, p. 42-51 10 p.

Research output: Contribution to journalArticle

Sclerosing Cholangitis
Cholangiocarcinoma
Early Diagnosis
Biliary Tract
Chemoprevention
15 Citations (Scopus)

The AmpliChip CYP450 Test: Principles, Challenges, and Future Clinical Utility in Digestive Disease

Juran, B. D., Egan, L. J. & Lazaridis, K. N., Jul 2006, In : Clinical Gastroenterology and Hepatology. 4, 7, p. 822-830 9 p.

Research output: Contribution to journalArticle

Cytochrome P-450 Enzyme System
Pharmaceutical Preparations
Cytochrome P-450 CYP2D6
Gastrointestinal Diseases
Therapeutic Uses
2005
13 Citations (Scopus)
Gastrointestinal Diseases
Gastroenterology
Genomics
Proteomics
Technology
358 Citations (Scopus)

Cholangiocarcinoma

Lazaridis, K. N. & Gores, G. J., May 2005, In : Gastroenterology. 128, 6, p. 1655-1667 13 p.

Research output: Contribution to journalArticle

Bile Duct Neoplasms
Intrahepatic Bile Ducts
Cholangiocarcinoma
1 Citation (Scopus)

Erratum: Cholangiocarcinoma (Gastroenterology (2005) 128 (1655-1667))

Lazaridis, K. N. & Gores, G. J., Jul 2005, In : Gastroenterology. 129, 1, p. 400 1 p.

Research output: Contribution to journalArticle

Cholangiocarcinoma
Gastroenterology
2 Citations (Scopus)

Examining the increased IgM production and ursodeoxycholic acid treatment in PBC

Lazaridis, K. N. & La Russo, N. F., Feb 2005, In : Gastroenterology. 128, 2, p. 498-500 3 p.

Research output: Contribution to journalArticle

Cholagogues and Choleretics
Immunologic Memory
Ursodeoxycholic Acid
Biliary Liver Cirrhosis
Immunoglobulin M
7 Citations (Scopus)

Genomics, genetic epidemiology, and genomic medicine

Lazaridis, K. N. & Petersen, G. M., Apr 2005, In : Clinical Gastroenterology and Hepatology. 3, 4, p. 320-328 9 p.

Research output: Contribution to journalArticle

Molecular Epidemiology
Genomics
Medicine
Human Genome
Physicians
3 Citations (Scopus)

Hematological malignancy manifesting as ascites

Lazaridis, K. N., Abraham, S. C. & Kamath, P. S., Feb 2005, In : Nature Clinical Practice Gastroenterology and Hepatology. 2, 2, p. 112-116 5 p.

Research output: Contribution to journalArticle

Hematologic Neoplasms
Ascites
Splenectomy
Surgical Splenorenal Shunt
Digestive System Endoscopy
5 Citations (Scopus)

Is the FXR the fix for cholesterol gallstone disease?

Juran, B. D. & Lazaridis, K. N., Jul 2005, In : Hepatology. 42, 1, p. 218-221 4 p.

Research output: Contribution to journalArticle

Gallstones
Cholesterol

Series of clinical genomics in gastroenterology and hepatology

Lazaridis, K. N. & Camilleri, M., Apr 2005, In : Clinical Gastroenterology and Hepatology. 3, 4, p. 319 1 p.

Research output: Contribution to journalArticle

Gastroenterology
Genomics
2004
53 Citations (Scopus)

A Large Set of Finnish Affected Sibling Pair Families with Type 2 Diabetes Suggests Susceptibility Loci on Chromosomes 6, 11, and 14

Silander, K., Scott, L. J., Valle, T. T., Mohlke, K. L., Stringham, H. M., Wiles, K. R., Duren, W. L., Doheny, K. F., Pugh, E. W., Chines, P., Narisu, N., White, P. P., Fingerlin, T. E., Jackson, A. U., Li, C., Ghosh, S., Magnuson, V. L., Colby, K., Erdos, M. R., Hill, J. E. & 26 others, Hollstein, P., Humphreys, K. M., Kasad, R. A., Lambert, J., Lazaridis, K. N., Lin, G., Morales-Mena, A., Patzkowski, K., Pfahl, C., Porter, R., Rha, D., Segal, L., Suh, Y. D., Tovar, J., Unni, A., Welch, C., Douglas, J. A., Epstein, M. P., Hauser, E. R., Hagopian, W., Buchanan, T. A., Watanabe, R. M., Bergman, R. N., Tuomilehto, J., Collins, F. S. & Boehnke, M., Mar 2004, In : Diabetes. 53, 3, p. 821-829 9 p.

Research output: Contribution to journalArticle

Chromosomes, Human, Pair 14
Chromosomes, Human, Pair 11
Chromosomes, Human, Pair 6
Finland
Type 2 Diabetes Mellitus
10 Citations (Scopus)

Differential expression of cholangiocyte and ileal bile acid transporters following bile acid supplementation and depletion

Kip, N. S., Lazaridis, K. N., Masyuk, A. I., Splinter, P. L., Huebert, R. C. & La Russo, N. F., May 15 2004, In : World Journal of Gastroenterology. 10, 10, p. 1440-1446 7 p.

Research output: Contribution to journalArticle

Taurocholic Acid
Bile Acids and Salts
Cholestyramine Resin
Diet
Intrahepatic Bile Ducts
259 Citations (Scopus)

The cholangiopathies: Disorders of biliary epithelia

Lazaridis, K. N., Strazzabosco, M. & La Russo, N. F., Nov 2004, In : Gastroenterology. 127, 5, p. 1565-1577 13 p.

Research output: Contribution to journalArticle

Bile Duct Diseases
Intrahepatic Bile Ducts
Biological Models
Epithelium
Epithelial Cells
74 Citations (Scopus)

Variation in the resistin gene is associated with obesity and insulin-related phenotypes in Finnish subjects

Conneely, K. N., Silander, K., Scott, L. J., Mohlke, K. L., Lazaridis, K. N., Valle, T. T., Tuomilehto, J., Bergman, R. N., Watanabe, R. M., Buchanan, T. A., Collins, F. S. & Boehnke, M., Oct 2004, In : Diabetologia. 47, 10, p. 1782-1788 7 p.

Research output: Contribution to journalArticle

Resistin
Type 2 Diabetes Mellitus
Obesity
Single Nucleotide Polymorphism
Insulin Resistance
2001
270 Citations (Scopus)

Ursodeoxycholic acid "mechanisms of action and clinical use in hepatobiliary disorders"

Lazaridis, K. N., Gores, G. J. & Lindor, K. D., 2001, In : Journal of Hepatology. 35, 1, p. 134-146 13 p.

Research output: Contribution to journalArticle

Ursodeoxycholic Acid
Alcoholic Liver Diseases
Liver
Cholestasis
Cystic Fibrosis
2000
98 Citations (Scopus)
Alternative Splicing
Bile Acids and Salts
Sodium
Ileum
Hepatocytes
1 Citation (Scopus)

Management of primary biliary cirrhosis: from diagnosis to end-stage disease.

Lazaridis, K. N. & Lindor, K. D., Apr 2000, In : Current Gastroenterology Reports. 2, 2, p. 94-98 5 p.

Research output: Contribution to journalArticle

Biliary Liver Cirrhosis
Liver Failure
Liver Diseases
Therapeutics
Ursodeoxycholic Acid
1999
151 Citations (Scopus)

Hepatic hydrothorax: Pathogenesis, diagnosis, and management

Lazaridis, K. N., Frank, J. W., Krowka, M. J. & Kamath, P. S., Sep 1999, In : American Journal of Medicine. 107, 3, p. 262-267 6 p.

Research output: Contribution to journalArticle

Hydrothorax
Liver
Liver Cirrhosis
Transjugular Intrahepatic Portasystemic Shunt
End Stage Liver Disease
1 Citation (Scopus)

Image of the month

Lazaridis, K. N. & Kamath, P. S., 1999, In : Gastroenterology. 116, 2

Research output: Contribution to journalArticle

Bile Duct Diseases
Glucagonoma
Therapeutic Embolization
Gallbladder Diseases
Hepatic Artery

Images in hepatology

Lazaridis, K. N. & Gores, G. J., 1999, In : Journal of Hepatology. 31, 6, p. 1086 1 p.

Research output: Contribution to journalArticle

Gastroenterology

Liver mass in a patient with primary sclerosing cholangitis.

Lazaridis, K. N. & Gores, G. J., Dec 1999, In : Journal of Hepatology. 31, 6, p. 1086 1 p.

Research output: Contribution to journalArticle

Sclerosing Cholangitis
X Ray Computed Tomography
Liver
1998
16 Citations (Scopus)

Images in hepatology. Arterio-portal fistula causing recurrent variceal bleeding.

Lazaridis, K. N. & Kamath, P. S., Jul 1998, In : Journal of Hepatology. 29, 1, p. 142 1 p.

Research output: Contribution to journalArticle

Gastrointestinal Hemorrhage
Biliary Liver Cirrhosis
Hepatic Artery
Arteriovenous Fistula
Gastroenterology
1997
2 Citations (Scopus)

28-year-old man with renal insufficiency and Jaundice

Lazaridis, K. N. & Kamath, P. S., 1997, In : Mayo Clinic Proceedings. 72, 11, p. 1057-1060 4 p.

Research output: Contribution to journalArticle

Jaundice
Renal Insufficiency
1 Citation (Scopus)

Image of the month

Lazaridis, K. N. & Kamath, P. S., 1997, In : Gastroenterology. 113, 1, p. 6 1 p.

Research output: Contribution to journalArticle

Peritoneal Neoplasms
Cystadenocarcinoma
Bile Duct Neoplasms
Intrahepatic Bile Ducts
X Ray Computed Tomography
52 Citations (Scopus)
Sodium-Glucose Transport Proteins
Monosaccharides
Reverse Transcriptase Polymerase Chain Reaction
Glucose
Bile
203 Citations (Scopus)

Rat cholangiocytes absorb bile acids at their apical domain via the ileal sodium-dependent bile acid transporter

Lazaridis, K. N., Pham, L., Tietz, P., Marinelli, R. A., DeGroen, P. C., Levine, S., Dawson, P. A. & La Russo, N. F., Dec 1 1997, In : Journal of Clinical Investigation. 100, 11, p. 2714-2721 8 p.

Research output: Contribution to journalArticle

Bile Acids and Salts
Taurocholic Acid
Liver
Transcytosis
sodium-bile acid cotransporter
1995
43 Citations (Scopus)

Analysis of transforming growth factor β and other cytokines in autoimmune exocrinopathy (Sjogren's syndrome)

Ogawa, N., Dang, H., Lazaridis, K. N., McGuff, H. S., Aufdemorte, T. B. & Talal, N., 1995, In : Journal of Interferon and Cytokine Research. 15, 9, p. 759-767 9 p.

Research output: Contribution to journalArticle

Sjogren's Syndrome
Transforming Growth Factors
Salivary Glands
Cytokines
Interleukin-10
1993
2 Citations (Scopus)

Cloning of a Human IgM Autoantibody Bearing a Cross-Reactive Idiotype in a λ. Expression Vector: A New Approach to Studying Autoantibodies

Dang, H., Lazaridis, K. N., Talal, N., Fischbach, M. & Sanz, I., Jun 1993, In : Clinical Immunology and Immunopathology. 67, 3, p. 249-256 8 p.

Research output: Contribution to journalArticle

Autoantibodies
Immunoglobulin M
Immunoglobulins
Organism Cloning
Immunoglobulin Fragments

Human κ chain expression in a λ phage vector: Methods of isolating amplified cDNA affects cloning efficiency

Lazaridis, K. N., Dang, H. & Talal, N., 1993, In : Human Antibodies and Hybridomas. 4, 3, p. 104-106 3 p.

Research output: Contribution to journalArticle

Bacteriophages
Organism Cloning
Complementary DNA
Chloroform
Phenol
37 Citations (Scopus)

Induction of lupus-associated autoantibodies by immunization with native and recombinant Ig polypeptides expressing a cross-reactive idiotype 4B4

Dang, H., Ogawa, N., Takei, M., Lazaridis, K. N. & Talal, N., Dec 15 1993, In : Journal of Immunology. 151, 12, p. 7260-7267 8 p.

Research output: Contribution to journalArticle

Autoantibodies
Immunization
Peptides
Antibodies
Immunoglobulin G