James L Kirkland, MD, PhD

Professor, Rochester, MN, General Internal Medicine

Emailkirkland.james@mayo.edu

Source: Scopus
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3 Not started
8 Finished

Sen-Survivors: An open-label intervention trial for frailty and senescence
Kirkland, J. L.
Project: Research project
Translational Geroscience Network
Kirkland, J. L.
National Institute on Aging
Project: Research project
Administrative and Biostatistics
LeBrasseur, N. K., Kirkland, J. L., Kirkland, J. L. & Khosla, S.
National Institute on Aging
Project: Research project
Senescent Cell Transplantation Model
Kirkland, J. L.
8/15/15 → 5/31/17
Project: Research project
Geroscience Network
Kirkland, J. L.
National Institutes of Health
9/30/13 → 6/30/16
Project: Research project

16664 Citations
68 Scopus h-Index
154 Article
37 Review article
6 Comment/debate
5 Chapter
More

Increased cellular senescence in the murine and human stenotic kidney: Effect of mesenchymal stem cells
Kim, S. R., Zou, X., Tang, H., Puranik, A. S., Abumoawad, A. M., Zhu, X. Y., Hickson, L. T. J., Tchkonia, T., Textor, S. C., Kirkland, J. L. & Lerman, L. O., Feb 2021, In: Journal of Cellular Physiology. 236, 2, p. 1332-1344 13 p.
Research output: Contribution to journal › Article › peer-review
Mechanisms of vascular dysfunction in the interleukin-10–deficient murine model of preeclampsia indicate nitric oxide dysregulation
Cubro, H., Nath, K. A., Suvakov, S., Garcia-Valencia, O., Parashuram, S., White, W. M., Weissgerber, T. L., Nath, M. C., Milic, N. M., Sontag, F., d'Uscio, L. V., Zhu, Y., Kirkland, J. L., Tchkonia, T., Alexander, M. P., Quinton, R. A., Katusic, Z. S., Grande, J. P. & Garovic, V. D., Mar 2021, In: Kidney international. 99, 3, p. 646-656 11 p.
Research output: Contribution to journal › Article › peer-review
Quercetin Reverses Cardiac Systolic Dysfunction in Mice Fed with a High-Fat Diet: Role of Angiogenesis
Yu, S., Kim, S. R., Jiang, K., Ogrodnik, M., Zhu, X. Y., Ferguson, C. M., Tchkonia, T., Lerman, A., Kirkland, J. L. & Lerman, L. O., 2021, In: Oxidative Medicine and Cellular Longevity. 2021, 8875729.
Research output: Contribution to journal › Article › peer-review

Open Access
Senolytic Drugs: Reducing Senescent Cell Viability to Extend Health Span
Robbins, P. D., Jurk, D., Khosla, S., Kirkland, J. L., LeBrasseur, N. K., Miller, J. D., Passos, J. F., Pignolo, R. J., Tchkonia, T. & Niedernhofer, L. J., Jan 6 2021, In: Annual Review of Pharmacology and Toxicology. 61, p. 779-803 25 p.
Research output: Contribution to journal › Review article › peer-review
2 Scopus citations
SMAD4 mutations and cross-talk between TGF-β/IFNγ signaling accelerate rates of DNA damage and cellular senescence, resulting in a segmental progeroid syndrome—the Myhre syndrome
Kandhaya-Pillai, R., Hou, D., Zhang, J., Yang, X., Compoginis, G., Mori, T., Tchkonia, T., Martin, G. M., Hisama, F. M., Kirkland, J. L. & Oshima, J., 2021, (Accepted/In press) In: GeroScience.
Research output: Contribution to journal › Article › peer-review
1 Scopus citations