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  • 17 Similar Profiles
Adipocytes Medicine & Life Sciences
Fats Medicine & Life Sciences
Cell Aging Medicine & Life Sciences
Adipose Tissue Medicine & Life Sciences
Aging of materials Chemical Compounds
Therapeutics Medicine & Life Sciences
Inflammation Medicine & Life Sciences
Adipogenesis Medicine & Life Sciences

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Projects 1992 2021

AGING EFFECT ON PREADIPOCYTE DIFFERENTIATION

Kirkland, J. L.

National Institutes of Health

5/15/973/31/21

Project: Research projectResearch Project

Adipogenesis
Fats
CCAAT-Enhancer-Binding Protein-alpha
Cytokines
Adipocytes

OBESITY/NUTRITION RESEARCH CENTER

Kirkland, J. L., Must, A., Grand, R., Corkey, B. E., Roberts, S., Istfan, N., Miller, D., Chen, K., Kelly, K., Flier, J., Dietz, W., Colditz, G., Kelly, K., Colditz, G., Hu, F., Lowell, B., Roberts, S., Istfan, N., Chen, K., Flier, J., Dietz, W., Corkey, B. E., Fried, S., Miller, D., Rosen, E. & Corkey, B. E.

National Institutes of Health

9/30/923/31/18

Project: Research projectCenter Core Grants

Adipocytes
Research Personnel
Foster Home Care
Conditioned Culture Medium
Adipose Tissue

Imaging for Cellular Senescence

Kirkland, J. L. & Lowe, V. J.

National Institutes of Health

9/1/155/31/17

Project: Research projectExploratory/Developmental Grants

Cell Aging
Electrons
Luminescence
Autopsy
Leg

Senescent Cell Transplantation Model

Kirkland, J. L.

National Institutes of Health

8/15/155/31/17

Project: Research projectExploratory/Developmental Grants

Cell Transplantation
Cell Aging
Pharmaceutical Preparations
Chronic Disease
Glucose Intolerance

Geroscience Network

Kirkland, J. L.

National Institutes of Health

9/30/136/30/16

Project: Research projectResource-Related Research Projects

Chronic Disease
Curriculum
Geriatricians
Organized Financing
Health Care Costs

Research Output 1973 2018

  • 6834 Citations
  • 43 h-Index
  • 138 Article
  • 4 Chapter
  • 3 Review article
  • 1 Letter

Targeting senescent cholangiocytes and activated fibroblasts with B-cell lymphoma-extra large inhibitors ameliorates fibrosis in multidrug resistance 2 gene knockout (Mdr2−/−) mice

Moncsek, A., Al-Suraih, M. S., Trussoni, C. E., O'Hara, S. P., Splinter, P. L., Zuber, C., Patsenker, E., Valli, P. V., Fingas, C. D., Weber, A., Zhu, Y., Tchkonia, T., Kirkland, J. L., Gores, G. J., Müllhaupt, B., LaRusso, N. F. & Mertens, J. C. Jan 1 2018 In : Hepatology. 67, 1, p. 247-259 13 p.

Research output: Research - peer-reviewArticle

MDR Genes
Gene Knockout Techniques
B-Cell Lymphoma
Fibrosis
Fibroblasts
9 Citations

17α-estradiol alleviates age-related metabolic and inflammatory dysfunction in male mice without inducing feminization

Stout, M. B. , Steyn, F. J. , Jurczak, M. J. , Camporez, J. P. G. , Zhu, Y. , Hawse, J. R. , Jurk, D. , Palmer, A. K. , Xu, M. , Pirtskhalava, T. , Evans, G. L. , De Souza Santos, R. , Frank, A. P. , White, T. A. , Monroe, D. G. , Singh, R. J. , Casaclang-Verzosa, G. , Miller, J. D. , Clegg, D. J. , LeBrasseur, N. K. & 4 others Von Zglinicki, T., Shulman, G. I., Tchkonia, T. & Kirkland, J. L. 2017 In : Journals of Gerontology - Series A Biological Sciences and Medical Sciences. 72, 1, p. 3-15 13 p.

Research output: Research - peer-reviewArticle

Feminization
Intra-Abdominal Fat
Estradiol
Glucose
Adiposity
2 Citations

Bilateral Oophorectomy and Accelerated Aging: Cause or Effect?

Rocca, W. A., Gazzuola Rocca, L., Smith, C. Y., Grossardt, B. R., Faubion, S. S., Shuster, L. T., Kirkland, J. L., Stewart, E. A. & Miller, V. M. Sep 1 2017 In : The journals of gerontology. Series A, Biological sciences and medical sciences. 72, 9, p. 1213-1217 5 p.

Research output: Research - peer-reviewArticle

Ovariectomy
Comorbidity
Epidemiology
Body Mass Index
Cohort Studies
11 Citations

Cellular Senescence: A Translational Perspective

Kirkland, J. L. & Tchkonia, T. Mar 13 2017 (Accepted/In press) In : EBioMedicine.

Research output: Research - peer-reviewArticle

Aging of materials
Tissue
Cell Aging
Phenotype
Geriatrics
11 Citations

Cellular senescence drives age-dependent hepatic steatosis

Ogrodnik, M., Miwa, S., Tchkonia, T., Tiniakos, D., Wilson, C. L., Lahat, A., Day, C. P., Burt, A., Palmer, A., Anstee, Q. M., Grellscheid, S. N., Hoeijmakers, J. H. J., Barnhoorn, S., Mann, D. A., Bird, T. G., Vermeij, W. P., Kirkland, J. L., Passos, J. F., Von Zglinicki, T. & Jurk, D. Jun 13 2017 In : Nature Communications. 8, 15691

Research output: Research - peer-reviewArticle

Cell Aging
Liver
Drive
Fats
Hepatocytes