Research Output

2014

CD28-mediated pro-survival signaling induces chemotherapeutic resistance in multiple myeloma

Murray, M. E., Gavile, C. M., Nair, J. R., Koorella, C., Carlson, L. M., Buac, D., Utley, A., Chesi, M., Bergsagel, P. L., Boise, L. H. & Lee, K. P., Jun 12 2014, In : Blood. 123, 24, p. 3770-3779 10 p.

Research output: Contribution to journalArticle

45 Scopus citations

Characterisation of Familial Colorectal Cancer Type X, Lynch syndrome, and non-familial colorectal cancer

Shiovitz, S., Copeland, W. K., Passarelli, M. N., Burnett-Hartman, A. N., Grady, W. M., Potter, J. D., Gallinger, S., Buchanan, D. D., Rosty, C., Win, A. K., Jenkins, M., Thibodeau, S. N., Haile, R., Baron, J. A., Marchand, L. L., Newcomb, P. A. & Lindor, N. M., Jul 29 2014, In : British journal of cancer. 111, 3, p. 598-602 5 p.

Research output: Contribution to journalArticle

27 Scopus citations

Clinical characteristics of ovarian cancer classified by BRCA1, BRCA2, and RAD51C status

Cunningham, J. M., Cicek, M. S., Larson, N. B., Davila, J., Wang, C., Larson, M. C., Song, H., Dicks, E. M., Harrington, P., Wick, M., Winterhoff, B. J., Hamidi, H., Konecny, G. E., Chien, J., Bibikova, M., Fan, J. B., Kalli, K. R., Lindor, N. M., Fridley, B. L., Pharoah, P. P. D. & 1 others, Goode, E. L., Feb 7 2014, In : Scientific reports. 4, 4026.

Research output: Contribution to journalArticle

62 Scopus citations

CMGRN: A web server for constructing multilevel gene regulatory networks using ChIP-seq and gene expression data

Guan, D., Shao, J., Deng, Y., Wang, P., Zhao, Z., Liang, Y., Wang, J. & Yan, B., Jan 1 2014, In : Bioinformatics. 30, 8, p. 1190-1192 3 p.

Research output: Contribution to journalArticle

18 Scopus citations

Colorectal cancer and self-reported tooth agenesis

Lindor, N. M., Win, A. K., Gallinger, S., Daftary, D., Thibodeau, S. N., Silva, R. & Letra, A., Mar 10 2014, In : Hereditary Cancer in Clinical Practice. 12, 1, 7.

Research output: Contribution to journalArticle

9 Scopus citations

Combination anti-CD137 and anti-CD40 antibody therapy in murine myc-driven hematological cancers

Westwood, J. A., Matthews, G. M., Shortt, J., Faulkner, D., Pegram, H. J., Duong, C. P. M., Chesi, M., Bergsagel, P. L., Sharp, L. L., Huhn, R. D., Darcy, P. K., Johnstone, R. W. & Kershaw, M. H., Aug 2014, In : Leukemia Research. 38, 8, p. 948-954 7 p.

Research output: Contribution to journalArticle

8 Scopus citations

Communication of genetic test results to family and health-care providers following disclosure of research results

Graves, K. D., Sinicrope, P. S., Esplen, M. J., Peterson, S. K., Patten, C. A., Lowery, J., Sinicrope, F. A., Nigon, S. K., Borgen, J., Gorin, S. S., Keogh, L. A. & Lindor, N. M., Apr 2014, In : Genetics in Medicine. 16, 4, p. 294-301 8 p.

Research output: Contribution to journalArticle

21 Scopus citations

CTCF controls HOXA cluster silencing and mediates PRC2-repressive higher-order chromatin structure in NT2/D1 cells

Xu, M., Zhao, G. N., Lv, X., Liu, G., Wang, L. Y., Hao, D. L., Wang, J., Liu, D. P. & Liang, C. C., Jan 1 2014, In : Molecular and cellular biology. 34, 20, p. 3867-3879 13 p.

Research output: Contribution to journalArticle

20 Scopus citations

Current approaches to the treatment of metastatic brain tumours

Owonikoko, T. K., Arbiser, J., Zelnak, A., Shu, H. K. G., Shim, H., Robin, A. M., Kalkanis, S. N., Whitsett, T. G., Salhia, B., Tran, N. L., Ryken, T., Moore, M. K., Egan, K. M. & Olson, J. J., Apr 25 2014, In : Nature Reviews Clinical Oncology. 11, 4, p. 203-222 20 p.

Research output: Contribution to journalReview article

135 Scopus citations

DbPSHP: A database of recent positive selection across human populations

Li, M. J., Wang, L. Y., Xia, Z., Wong, M. P., Sham, P. C. & Wang, J., Jan 1 2014, In : Nucleic acids research. 42, D1, p. D910-D916

Research output: Contribution to journalArticle

29 Scopus citations

DDGni: Dynamic delay gene-network inference from high-temporal data using gapped local alignment

Yalamanchili, H. K., Yan, B., Li, M. J., Qin, J., Zhao, Z., Chin, F. Y. L. & Wang, J., Feb 1 2014, In : Bioinformatics. 30, 3, p. 377-383 7 p.

Research output: Contribution to journalArticle

18 Scopus citations

Development of human serine protease-based therapeutics targeting Fn14 and identification of Fn14 as a new target overexpressed in TNBC

Zhou, H., Mohamedali, K. A., Gonzalez-Angulo, A. M., Cao, Y., Migliorini, M., Cheung, L. H., LoBello, J., Lei, X., Qi, Y., Hittelman, W. N., Winkles, J. A., Tran, N. L. & Rosenblum, M. G., Nov 1 2014, In : Molecular cancer therapeutics. 13, 11, p. 2688-2705 18 p.

Research output: Contribution to journalArticle

11 Scopus citations

DNA Glycosylases Involved in Base Excision Repair May Be Associated with Cancer Risk in BRCA1 and BRCA2 Mutation Carriers

Osorio, A., Milne, R. L., Kuchenbaecker, K., Vaclová, T., Pita, G., Alonso, R., Peterlongo, P., Blanco, I., de la Hoya, M., Duran, M., Díez, O., Ramón y Cajal, T., Konstantopoulou, I., Martínez-Bouzas, C., Andrés Conejero, R., Soucy, P., McGuffog, L., Barrowdale, D., Lee, A., Arver, B. & 177 others, Rantala, J., Loman, N., Ehrencrona, H., Olopade, O. I., Beattie, M. S., Domchek, S. M., Nathanson, K., Rebbeck, T. R., Arun, B. K., Karlan, B. Y., Walsh, C., Lester, J., John, E. M., Whittemore, A. S., Daly, M. B., Southey, M., Hopper, J., Terry, M. B., Buys, S. S., Janavicius, R., Dorfling, C. M., van Rensburg, E. J., Steele, L., Neuhausen, S. L., Ding, Y. C., Hansen, T. V. O., Jønson, L., Ejlertsen, B., Gerdes, A. M., Infante, M., Herráez, B., Moreno, L. T., Weitzel, J. N., Herzog, J., Weeman, K., Manoukian, S., Peissel, B., Zaffaroni, D., Scuvera, G., Bonanni, B., Mariette, F., Volorio, S., Viel, A., Varesco, L., Papi, L., Ottini, L., Tibiletti, M. G., Radice, P., Yannoukakos, D., Garber, J., Ellis, S., Frost, D., Platte, R., Fineberg, E., Evans, G., Lalloo, F., Izatt, L., Eeles, R., Adlard, J., Davidson, R., Cole, T., Eccles, D., Cook, J., Hodgson, S., Brewer, C., Tischkowitz, M., Douglas, F., Porteous, M., Side, L., Walker, L., Morrison, P., Donaldson, A., Kennedy, J., Foo, C., Godwin, A. K., Schmutzler, R. K., Wappenschmidt, B., Rhiem, K., Engel, C., Meindl, A., Ditsch, N., Arnold, N., Plendl, H. J., Niederacher, D., Sutter, C., Wang-Gohrke, S., Steinemann, D., Preisler-Adams, S., Kast, K., Varon-Mateeva, R., Gehrig, A., Stoppa-Lyonnet, D., Sinilnikova, O. M., Mazoyer, S., Damiola, F., Poppe, B., Claes, K., Piedmonte, M., Tucker, K., Backes, F., Rodríguez, G., Brewster, W., Wakeley, K., Rutherford, T., Caldés, T., Nevanlinna, H., Aittomäki, K., Rookus, M. A., van Os, T. A. M., van der Kolk, L., de Lange, J. L., Meijers-Heijboer, H. E. J., van der Hout, A. H., van Asperen, C. J., Gómez Garcia, E. B., Hoogerbrugge, N., Collée, J. M., van Deurzen, C. H. M., van der Luijt, R. B., Devilee, P., Olah, E., Lázaro, C., Teulé, A., Menéndez, M., Jakubowska, A., Cybulski, C., Gronwald, J., Lubinski, J., Durda, K., Jaworska-Bieniek, K., Johannsson, O. T., Maugard, C., Montagna, M., Tognazzo, S., Teixeira, M. R., Healey, S., Olswold, C., Guidugli, L., Lindor, N., Slager, S., Szabo, C. I., Vijai, J., Robson, M., Kauff, N., Zhang, L., Rau-Murthy, R., Fink-Retter, A., Singer, C. F., Rappaport, C., Geschwantler Kaulich, D., Pfeiler, G., Tea, M. K., Berger, A., Phelan, C. M., Greene, M. H., Mai, P. L., Lejbkowicz, F., Andrulis, I., Mulligan, A. M., Glendon, G., Toland, A. E., Bojesen, A., Pedersen, I. S., Sunde, L., Thomassen, M., Kruse, T. A., Jensen, U. B., Friedman, E., Laitman, Y., Shimon, S. P., Simard, J., Easton, D. F., Offit, K., Couch, F. J., Chenevix-Trench, G., Antoniou, A. C. & Benitez, J., Apr 2014, In : PLoS genetics. 10, 4, e1004256.

Research output: Contribution to journalArticle

23 Scopus citations

Does risk of endometrial cancer for women without a germline mutation in a DNA mismatch repair gene depend on family history of endometrial cancer or colorectal cancer?

Bharati, R., Jenkins, M. A., Lindor, N. M., Le Marchand, L., Gallinger, S., Haile, R. W., Newcomb, P. A., Hopper, J. L. & Win, A. K., May 2014, In : Gynecologic oncology. 133, 2, p. 287-292 6 p.

Research output: Contribution to journalArticle

17 Scopus citations

Echocardiographic particle imaging velocimetry data assimilation with least square finite element methods

Rajaraman, P. K., Manteuffel, T. A., Belohlavek, M., McMahon, E. & Heys, J. J., Dec 1 2014, In : Computers and Mathematics with Applications. 68, 11, p. 1569-1580 12 p.

Research output: Contribution to journalArticle

5 Scopus citations

Enter protein m

Grover, R. K., Zhu, X., Nieusma, T., Jones, T., Boero, I., MacLeod, A. S., Mark, A., Niessen, S., Kim, H. J., Kong, L., Assad-Garcia, N., Kwon, K., Chesi, M., Smider, V. V., Salomon, D. R., Jelinek, D. F., Kyle, R. A., Pyles, R. B., Glass, J. I., Ward, A. B. & 2 others, Wilson, I. A. & Lerner, R. A., May 1 2014, In : Assay and Drug Development Technologies. 12, 4, p. 204-206 3 p.

Research output: Contribution to journalComment/debate

Exploring the function of genetic variants in the non-coding genomic regions: Approaches for identifying human regulatory variants affecting gene expression

Li, M. J., Yan, B., Sham, P. C. & Wang, J., Aug 2 2014, In : Briefings in bioinformatics. 16, 3, p. 393-412 20 p., bbu018.

Research output: Contribution to journalArticle

25 Scopus citations

Family history of colorectal cancer is not associated with colorectal cancer survival regardless of microsatellite instability status

Phipps, A. I., Ahnen, D. J., Campbell, P. T., Win, A. K., Jenkins, M. A., Lindor, N. M., Gryfe, R., Potter, J. D. & Newcomb, P. A., Aug 2014, In : Cancer Epidemiology Biomarkers and Prevention. 23, 8, p. 1700-1704 5 p.

Research output: Contribution to journalReview article

7 Scopus citations

FaSD-somatic: A fast and accurate somatic SNV detection algorithm for cancer genome sequencing data

Wang, W., Wang, P., Xu, F., Luo, R., Wong, M. P., Lam, T. W. & Wang, J., Sep 1 2014, In : Bioinformatics. 30, 17, p. 2498-2500 3 p.

Research output: Contribution to journalArticle

10 Scopus citations

FN14 expression correlates with MET in NSCLC and promotes MET-driven cell invasion

Whitsett, T. G., Fortin Ensign, S. P., Dhruv, H. D., Inge, L. J., Kurywchak, P., Wolf, K. K., LoBello, J., Kingsley, C. B., Allen, J. W., Weiss, G. J. & Tran, N. L., Aug 2014, In : Clinical and Experimental Metastasis. 31, 6, p. 613-623 11 p.

Research output: Contribution to journalArticle

14 Scopus citations

Fragile X syndrome due to a missense mutation

Myrick, L. K., Nakamoto-Kinoshita, M., Lindor, N. M., Kirmani, S., Cheng, X. & Warren, S. T., Oct 11 2014, In : European Journal of Human Genetics. 22, 10, p. 1185-1189 5 p.

Research output: Contribution to journalArticle

42 Scopus citations

Genetic variation in prostaglandin synthesis and related pathways, NSAID use and colorectal cancer risk in the colon Cancer Family Registry

Resler, A. J., Makar, K. W., Heath, L., Whitton, J., Potter, J. D., Poole, E. M., Habermann, N., Scherer, D., Duggan, D., Wang, H., Lindor, N. M., Passarelli, M. N., Baron, J. A., Newcomb, P. A., Le Marchand, L. & Ulrich, C. M., Sep 2014, In : Carcinogenesis. 35, 9, p. 2121-2126 6 p., bgu119.

Research output: Contribution to journalArticle

10 Scopus citations
10 Scopus citations

Growth differentiating factor 15 enhances the tumor-initiating and self-renewal potential of multiple myeloma cells

Tanno, T., Lim, Y., Wang, Q., Chesi, M., Bergsagel, P. L., Matthews, G., Johnstone, R. W., Ghosh, N., Borrello, I., Huff, C. A. & Matsui, W., Jan 30 2014, In : Blood. 123, 5, p. 725-733 9 p.

Research output: Contribution to journalArticle

38 Scopus citations

Guanine nucleotide exchange factor Dock7 mediates HGF-induced glioblastoma cell invasion via Rac activation

Murray, D. W., Didier, S., Chan, A., Paulino, V., Van Aelst, L., Ruggieri, R., Tran, N. L., Byrne, A. T. & Symons, M., Mar 4 2014, In : British journal of cancer. 110, 5, p. 1307-1315 9 p.

Research output: Contribution to journalArticle

16 Scopus citations

High prevalence of mismatch repair deficiency in prostate cancers diagnosed in mismatch repair gene mutation carriers from the colon cancer family registry

Rosty, C., Walsh, M. D., Lindor, N. M., Thibodeau, S. N., Mundt, E., Gallinger, S., Aronson, M., Pollett, A., Baron, J. A., Pearson, S., Clendenning, M., Walters, R. J., Nagler, B. N., Crawford, W. J., Young, J. P., Winship, I., Win, A. K., Hopper, J. L., Jenkins, M. A. & Buchanan, D. D., Jan 1 2014, In : Familial Cancer. 13, 4, p. 573-582 10 p.

Research output: Contribution to journalArticle

30 Scopus citations

How do researchers manage genetic results in practice? The experience of the multinational Colon Cancer Family Registry

Keogh, L. A., Fisher, D., Sheinfeld Gorin, S., Schully, S. D., Lowery, J. T., Ahnen, D. J., Maskiell, J. A., Lindor, N. M., Hopper, J. L., Burnett, T., Holter, S., Arnold, J. L., Gallinger, S., Laurino, M., Esplen, M. J. & Sinicrope, P. S., Apr 2014, In : Journal of Community Genetics. 5, 2, p. 99-108 10 p.

Research output: Contribution to journalArticle

15 Scopus citations

Identification and validation of an anthracycline/cyclophosphamide-based chemotherapy response assay in breast cancer

Mulligan, J. M., Hill, L. A., Deharo, S., Irwin, G., Boyle, D., Keating, K. E., Raji, O. Y., McDyer, F. A., O'Brien, E., Bylesjo, M., Quinn, J. E., Lindor, N. M., Mullan, P. B., James, C. R., Walker, S. M., Kerr, P., James, J., Davison, T. S., Proutski, V., Salto-Tellez, M. & 4 others, Johnston, P. G., Couch, F. J., Paul Harkin, D. & Kennedy, R. D., 2014, In : Journal of the National Cancer Institute. 106, 1, djt335.

Research output: Contribution to journalArticle

55 Scopus citations

Identification of susceptibility loci for colorectal cancer in a genome-wide meta-analysis

Whiffin, N., Hosking, F. J., Farrington, S. M., Palles, C., Dobbins, S. E., Zgaga, L., Lloyd, A., Kinnersley, B., Gorman, M., Tenesa, A., Broderick, P., Wang, Y., Barclay, E., Hayward, C., Martin, L., Buchanan, D. D., Win, A. K., Hopper, J., Jenkins, M., Lindor, N. M. & 11 others, Newcomb, P. A., Gallinger, S., Conti, D., Schumacher, F., Casey, G., Liu, T., Campbell, H., Lindblom, A., Houlston, R. S., Tomlinson, I. P. & Dunlop, M. G., Sep 2014, In : Human molecular genetics. 23, 17, p. 4729-4737 9 p., ddu177.

Research output: Contribution to journalArticle

86 Scopus citations

Implementing individualized medicine into the medical practice

Lazaridis, K. N., MCAllister, T. M., Babovic-Vuksanovic, D., Beck, S. A., Borad, M. J., Bryce, A. H., Chanan-Khan, A. A., Ferber, M. J., Fonseca, R., Johnson, K. J., Klee, E. W., Lindor, N. M., McCormick, J. B., MCWilliams, R. R., Parker, A. S., Riegert-Johnson, D. L., Rohrer Vitek, C. R., Schahl, K. A., Schultz, C., Stewart, K. & 3 others, Then, G. C., Wieben, E. D. & Farrugia, G., Mar 2014, In : American Journal of Medical Genetics, Part C: Seminars in Medical Genetics. 166, 1, p. 15-23 9 p.

Research output: Contribution to journalArticle

40 Scopus citations

Imputation and subset-based association analysis across different cancer types identifies multiple independent risk loci in the TERT-CLPTM1L region on chromosome 5p15.33

Wang, Z., Zhu, B., Zhang, M., Parikh, H., Jia, J., Chung, C. C., Sampson, J. N., Hoskins, J. W., Hutchinson, A., Burdette, L., Ibrahim, A., Hautman, C., Raj, P. S., Abnet, C. C., Adjei, A. A., Ahlbom, A., Albanes, D., Allen, N. E., Ambrosone, C. B., Aldrich, M. & 331 others, Amiano, P., Amos, C., Andersson, U., Gerald Andriole, G. A., Andrulis, I. L., Arici, C., Arslan, A. A., Austin, M. A., Baris, D., Barkauskas, D. A., Bassig, B. A., Freeman, L. E. B., Berg, C. D., Berndt, S. I., Bertazzi, P. A., Biritwum, R. B., Black, A., Blot, W., Boeing, H., Boffetta, P., Bolton, K., Boutron-Ruault, M. C., Bracci, P. M., Brennan, P., Brinton, L. A., Brotzman, M., Bueno-de-Mesquita, H. B., Buring, J. E., Butler, M. A., Cai, Q., Cancel-Tassin, G., Canzian, F., Cao, G., Caporaso, N. E., Carrato, A., Carreon, T., Carta, A., Chang, G. C., Chang, I. S., Chang-Claude, J., Che, X., Chen, C. J., Chen, C. Y., Chen, C. H., Chen, C., Chen, K. Y., Chen, Y. M., Chokkalingam, A. P., Chu, L. W., Clavel-Chapelon, F., Colditz, G. A., Colt, J. S., Conti, D., Cook, M. B., Cortessis, V. K., Crawford, E. D., Cussenot, O., Davis, F. G., De Vivo, I., Deng, X., Ding, T., Dinney, C. P., Di Stefano, A. L., Diver, W. R., Duell, E. J., Elena, J. W., Fan, J. H., Feigelson, H. S., Feychting, M., Figueroa, J. D., Flanagan, A. M., Fraumeni, J. F., Freedman, N. D., Fridley, B. L., Fuchs, C. S., Gago-Dominguez, M., Gallinger, S., Gao, Y. T., Gapstur, S. M., Garcia-Closas, M., Garcia-Closas, R., Gastier-Foster, J. M., Gaziano, J. M., Gerhard, D. S., Giffen, C. A., Giles, G. G., Gillanders, E. M., Giovannucci, E. L., Goggins, M., Gokgoz, N., Goldstein, A. M., Gonzalez, C., Gorlick, R., Greene, M. H., Gross, M., Grossman, H. B., Grubb, R., Gu, J., Guan, P., Haiman, C. A., Hallmans, G., Hankinson, S. E., Harris, C. C., Hartge, P., Hattinger, C., Hayes, R. B., He, Q., Helman, L., Henderson, B. E., Henriksson, R., Hoffman-Bolton, J., Hohensee, C., Holly, E. A., Hong, Y. C., Hoover, R. N., Dean Hosgood, H., Hsiao, C. F., Hsing, A. W., Hsiung, C. A., Hu, N., Hu, W., Hu, Z., Huang, M. S., Hunter, D. J., Inskip, P. D., Ito, H., Jacobs, E. J., Jacobs, K. B., Jenab, M., Ji, B. T., Johansen, C., Johansson, M., Johnson, A., Kaaks, R., Kamat, A. M., Kamineni, A., Karagas, M., Khanna, C., Khaw, K. T., Kim, C., Kim, I. S., Kim, J. H., Kim, Y. H., Kim, Y. C., Kim, Y. T., Kang, C. H., Jung, Y. J., Kitahara, C. M., Klein, A. P., Klein, R., Kogevinas, M., Koh, W. P., Kohno, T., Kolonel, L. N., Kooperberg, C., Kratz, C. P., Krogh, V., Kunitoh, H., Kurtz, R. C., Kurucu, N., Lan, Q., Lathrop, M., Lau, C. C., Lecanda, F., Lee, K. M., Lee, M. P., Marchand, L. L., Lerner, S. P., Li, D., Liao, L. M., Lim, W. Y., Lin, D., Lin, J., Lindstrom, S., Linet, M. S., Lissowska, J., Liu, J., Ljungberg, B., Lloreta, J., Lu, D., Ma, J., Malats, N., Mannisto, S., Marina, N., Mastrangelo, G., Matsuo, K., McGlynn, K. A., McKean-Cowdin, R., McNeil, L. H., McWilliams, R. R., Melin, B. S., Meltzer, P. S., Mensah, J. E., Miao, X., Michaud, D. S., Mondul, A. M., Moore, L. E., Muir, K., Niwa, S., Olson, S. H., Orr, N., Panico, S., Park, J. Y., Patel, A. V., Patino-Garcia, A., Pavanello, S., Peeters, P. H. M., Peplonska, B., Peters, U., Petersen, G. M., Picci, P., Pike, M. C., Porru, S., Prescott, J., Pu, X., Purdue, M. P., Qiao, Y. L., Rajaraman, P., Riboli, E., Risch, H. A., Rodabough, R. J., Rothman, N., Ruder, A. M., Ryu, J. S., Sanson, M., Schned, A., Schumacher, F. R., Schwartz, A. G., Schwartz, K. L., Schwenn, M., Scotlandi, K., Seow, A., Serra, C., Serra, M., Sesso, H. D., Severi, G., Shen, H., Shen, M., Shete, S., Shiraishi, K., Shu, X. O., Siddiq, A., Sierrasesumaga, L., Sierri, S., Sihoe, A. D. L., Silverman, D. T., Simon, M., Southey, M. C., Spector, L., Spitz, M., Stampfer, M., Stattin, P., Stern, M. C., Stevens, V. L., Stolzenberg-Solomon, R. Z., Stram, D. O., Strom, S. S., Su, W. C., Sund, M., Sung, S. W., Swerdlow, A., Tan, W., Tanaka, H., Tang, W., Tang, Z. Z., Tardon, A., Tay, E., Taylor, P. R., Tettey, Y., Thomas, D. M., Tirabosco, R., Tjonneland, A., Tobias, G. S., Toro, J. R., Travis, R. C., Trichopoulos, D., Troisi, R., Truelove, A., Tsai, Y. H., Tucker, M. A., Tumino, R., Van Den Berg, D., Van Den Eeden, S. K., Vermeulen, R., Vineis, P., Visvanathan, K., Vogel, U., Wang, C., Wang, C., Wang, J., Wang, S. S., Weiderpass, E., Weinstein, S. J., Wentzensen, N., Wheeler, W., White, E., Wiencke, J. K., Wolk, A., Wolpin, B. M., Wong, M. P., Wrensch, M., Wu, C., Wu, T., Wu, X., Wu, Y. L., Wunder, J. S., Xiang, Y. B., Xu, J., Yang, H. P., Yang, P. C., Yatabe, Y., Ye, Y., Yeboah, E. D., Yin, Z., Ying, C., Yu, C. J., Yu, K., Yuan, J. M., Zanetti, K. A., Zeleniuch-Jacquotte, A., Zheng, W., Zhou, B., Mirabello, L., Savage, S. A., Kraft, P., Chanock, S. J., Yeager, M., Landi, M. T., Shi, J., Chatterjee, N. & Amundadottir, L. T., Nov 15 2014, In : Human molecular genetics. 23, 24, p. 6616-6633 18 p.

Research output: Contribution to journalArticle

62 Scopus citations

Inferring gene regulatory networks by integrating ChIP-seq/chip and transcriptome data via LASSO-type regularization methods

Qin, J., Hu, Y., Xu, F., Yalamanchili, H. K. & Wang, J., Jun 1 2014, In : Methods. 67, 3, p. 294-303 10 p.

Research output: Contribution to journalArticle

25 Scopus citations

Inhibition of KAP1 enhances hypoxia-induced Kaposi's sarcoma-associated herpesvirus reactivation through RBP-Jk

Zhang, L., Zhu, C., Guo, Y., Wei, F., Lu, J., Qin, J., Banerjee, S., Wang, J., Shang, H., Verma, S. C., Yuan, Z., Robertson, E. S. & Cai, Q., Jun 2014, In : Journal of virology. 88, 12, p. 6873-6884 12 p.

Research output: Contribution to journalArticle

34 Scopus citations

Integrated genomic and epigenomic analysis of breast cancer brain metastasis

Salhia, B., Kiefer, J., Ross, J. T. D., Metapally, R., Martinez, R. A., Johnson, K. N., DiPerna, D. M., Paquette, K. M., Jung, S., Nasser, S., Wallstrom, G., Tembe, W., Baker, A., Carpten, J., Resau, J., Ryken, T., Sibenaller, Z., Petricoin, E. F., Liotta, L. A., Ramanathan, R. K. & 2 others, Berens, M. E. & Tran, N. L., Jan 29 2014, In : PloS one. 9, 1, e85448.

Research output: Contribution to journalArticle

63 Scopus citations

LKB1 inactivation sensitizes non-small cell lung cancer to pharmacological aggravation of ER stress

Inge, L. J., Friel, J. M., Richer, A. L., Fowler, A. J., Whitsett, T., Smith, M. A., Tran, N. L. & Bremner, R. M., Oct 1 2014, In : Cancer Letters. 352, 2, p. 187-195 9 p.

Research output: Contribution to journalArticle

12 Scopus citations
5 Scopus citations

Mcl-1 mediates TWEAK/Fn14-induced non-small cell lung cancer survival and therapeutic response

Whitsett, T. G., Mathews, I. T., Cardone, M. H., Lena, R. J., Pierceall, W. E., Bittner, M., Sima, C., LoBello, J., Weiss, G. J. & Tran, N. L., Apr 2014, In : Molecular Cancer Research. 12, 4, p. 550-559 10 p.

Research output: Contribution to journalArticle

22 Scopus citations

Pathogenesis of multiple myeloma

Chesi, M. & Bergsagel, P. L., Jan 1 2014, Multiple Myeloma: Diagnosis and Treatment. Springer New York, p. 35-46 12 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

1 Scopus citations

Pilot Study: Evaluation of Dual-Energy Computed Tomography Measurement Strategies for Positron Emission Tomography Correlation in Pancreatic Adenocarcinoma

Oldan, J., He, M., Wu, T., Silva, A. C., Li, J., Mitchell, J. R., Pavlicek, W. M., Roarke, M. C. & Hara, A. K., Nov 6 2014, In : Journal of Digital Imaging. 27, 6, p. 824-832 9 p.

Research output: Contribution to journalArticle

5 Scopus citations

Pleiotropic effects of genetic risk variants for other cancers on colorectal cancer risk: PAGE, GECCO and CCFR consortia

Cheng, I., Kocarnik, J. M., Dumitrescu, L., Lindor, N. M., Chang-Claude, J., Avery, C. L., Caberto, C. P., Love, S. A., Slattery, M. L., Chan, A. T., Baron, J. A., Hindorff, L. A., Park, S. L., Schumacher, F. R., Hoffmeister, M., Kraft, P., Butler, A. M., Duggan, D. J., Hou, L., Carlson, C. S. & 47 others, Monroe, K. R., Lin, Y., Carty, C. L., Mann, S., Ma, J., Giovannucci, E. L., Fuchs, C. S., Newcomb, P. A., Jenkins, M. A., Hopper, J. L., Haile, R. W., Conti, D. V., Campbell, P. T., Potter, J. D., Caan, B. J., Schoen, R. E., Hayes, R. B., Chanock, S. J., Berndt, S. I., Küry, S., Bézieau, S., Ambite, J. L., Kumaraguruparan, G., Richardson, D. M., Goodloe, R. J., Dilks, H. H., Baker, P., Zanke, B. W., Lemire, M., Gallinger, S., Hsu, L., Jiao, S., Harrison, T. A., Seminara, D., Haiman, C. A., Kooperberg, C., Wilkens, L. R., Hutter, C. M., White, E., Crawford, D. C., Heiss, G., Hudson, T. J., Brenner, H., Bush, W. S., Casey, G., Le Marchand, L. & Peters, U., May 1 2014, In : Gut. 63, 5, p. 800-807 8 p.

Research output: Contribution to journalArticle

21 Scopus citations

Promiscuous MYC locus rearrangements hijack enhancers but mostly super-enhancers to dysregulate MYC expression in multiple myeloma

Affer, M., Chesi, M., Chen, W. D., Keats, J. J., Demchenko, Y. N., Tamizhmani, K., Garbitt, V. M., Riggs, D. L., Brents, L. A., Roschke, A. V., Van Wier, S., Fonseca, R., Bergsagel, P. L. & Kuehl, W. M., Aug 2014, In : Leukemia. 28, 8, p. 1725-1735 11 p.

Research output: Contribution to journalArticle

132 Scopus citations

PTHGRN: Unraveling post-translational hierarchical gene regulatory networks using PPI, ChIP-seq and gene expression data

Guan, D., Shao, J., Zhao, Z., Wang, P., Qin, J., Deng, Y., Boheler, K. R., Wang, J. & Yan, B., Jul 1 2014, In : Nucleic acids research. 42, W1, p. W130-W136

Research output: Contribution to journalArticle

16 Scopus citations

Refined histopathological predictors of BRCA1 and BRCA2 mutation status: A large-scale analysis of breast cancer characteristics from the BCAC, CIMBA, and ENIGMA consortia

ABCTB Investigators, EMBRACE Group, GENICA-Network, HEBON Group & KConFab investigators, Dec 23 2014, In : Breast Cancer Research. 16, 1, 3419.

Research output: Contribution to journalArticle

Open Access
49 Scopus citations

Rho GTPases and their activators, guanine nucleotide exchange factors (GEFs): Their roles in glioma cell invasion

Hu, B., Symons, M., Salhia, B., Fortin, S. P., Tran, N. L., Rutka, J. & Cheng, S. Y., Jan 1 2014, Signaling Pathways and Molecular Mediators in Metastasis. Springer Netherlands, p. 143-169 27 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

1 Scopus citations

Risk of colorectal cancer for carriers of mutations in MUTYH, with and without a family history of cancer

Win, A. K., Dowty, J. G., Cleary, S. P., Kim, H., Buchanan, D. D., Young, J. P., Clendenning, M., Rosty, C., Macinnis, R. J., Giles, G. G., Boussioutas, A., Macrae, F. A., Parry, S., Goldblatt, J., Baron, J. A., Burnett, T., Le Marchand, L., Newcomb, P. A., Haile, R. W., Hopper, J. L. & 6 others, Cotterchio, M., Gallinger, S., Lindor, N. M., Tucker, K. M., Winship, I. M. & Jenkins, M. A., May 2014, In : Gastroenterology. 146, 5, p. 1208-1211.e5

Research output: Contribution to journalArticle

82 Scopus citations

SpliceNet: Recovering splicing isoform-specific differential gene networks from RNA-Seq data of normal and diseased samples

Yalamanchili, H. K., Li, Z., Wang, P., Wong, M. P., Yao, J. & Wang, J., 2014, In : Nucleic acids research. 42, 15, p. e121

Research output: Contribution to journalArticle

12 Scopus citations

The drug vehicle and solvent N-Methylpyrrolidone is an immunomodulator and antimyeloma compound

Shortt, J., Hsu, A. K., Martin, B. P., Doggett, K., Matthews, G. M., Doyle, M. A., Ellul, J., Jockel, T. E., Andrews, D. M., Hogg, S. J., Reitsma, A., Faulkner, D., Bergsagel, P. L., Chesi, M., Heath, J. K., Denny, W. A., Thompson, P. E., Neeson, P. J., Ritchie, D. S., McArthur, G. A. & 1 others, Johnstone, R. W., May 22 2014, In : Cell reports. 7, 4, p. 1009-1019 11 p.

Research output: Contribution to journalArticle

23 Scopus citations

The PI3K inhibitor GDC-0941 combines with existing clinical regimens for superior activity in multiple myeloma

Munugalavadla, V., Mariathasan, S., Slaga, D., Du, C., Berry, L., Del Rosario, G., Yan, Y., Boe, M., Sun, L., Friedman, L. S., Chesi, M., Leif Bergsagel, P. & Ebens, A., Jan 16 2014, In : Oncogene. 33, 3, p. 316-325 10 p.

Research output: Contribution to journalArticle

27 Scopus citations

TPL2 kinase regulates the inflammatory milieu of the myeloma niche

Hope, C., Ollar, S. J., Heninger, E., Hebron, E., Jensen, J. L., Kim, J., Maroulakou, I., Miyamoto, S., Leith, C., Yang, D. T., Callander, N., Hematti, P., Chesi, M., Bergsagel, P. L. & Asimakopoulos, F., May 22 2014, In : Blood. 123, 21, p. 3305-3315 11 p.

Research output: Contribution to journalArticle

50 Scopus citations

Trans-ethnic genome-wide association study of colorectal cancer identifies a new susceptibility locus in VTI1A

Wang, H., Burnett, T., Kono, S., Haiman, C. A., Iwasaki, M., Wilkens, L. R., Loo, L. W. M., Van Den Berg, D., Kolonel, L. N., Henderson, B. E., Keku, T. O., Sandler, R. S., Signorello, L. B., Blot, W. J., Newcomb, P. A., Pande, M., Amos, C. I., West, D. W., Bézieau, S., Berndt, S. I. & 15 others, Zanke, B. W., Hsu, L., Lindor, N. M., Haile, R. W., Hopper, J. L., Jenkins, M. A., Gallinger, S., Casey, G., Stenzel, S. L., Schumacher, F. R., Peters, U., Gruber, S. B., Tsugane, S., Stram, D. O. & Le Marchand, L., Aug 8 2014, In : Nature communications. 5, 4613.

Research output: Contribution to journalArticle

50 Scopus citations