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  • 2021

    Analysis in the Prospective Lynch Syndrome Database identifies sarcoma as part of the Lynch syndrome tumor spectrum

    PLSD Collaborators, Jan 15 2021, In: International Journal of Cancer. 148, 2, p. 512-513 2 p.

    Research output: Contribution to journalLetterpeer-review

    1 Scopus citations
  • Automatic segmentation of the left ventricle in echocardiographic images using convolutional neural networks

    Kim, T., Hedayat, M., Vaitkus, V. V., Belohlavek, M., Krishnamurthy, V. & Borazjani, I., May 2021, In: Quantitative Imaging in Medicine and Surgery. 11, 5, p. 1763-1781 19 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
  • Cross-oncopanel study reveals high sensitivity and accuracy with overall analytical performance depending on genomic regions

    Gong, B., Li, D., Kusko, R., Novoradovskaya, N., Zhang, Y., Wang, S., Pabón-Peña, C., Zhang, Z., Lai, K., Cai, W., LoCoco, J. S., Lader, E., Richmond, T. A., Mittal, V. K., Liu, L. C., Johann, D. J., Willey, J. C., Bushel, P. R., Yu, Y., Xu, C. & 131 others, Chen, G., Burgess, D., Cawley, S., Giorda, K., Haseley, N., Qiu, F., Wilkins, K., Arib, H., Attwooll, C., Babson, K., Bao, L., Bao, W., Lucas, A. B., Best, H., Bhandari, A., Bisgin, H., Blackburn, J., Blomquist, T. M., Boardman, L., Burgher, B., Butler, D. J., Chang, C. J., Chaubey, A., Chen, T., Chierici, M., Chin, C. R., Close, D., Conroy, J., Coleman, J. C., Craig, D. J., Crawford, E., del Pozo, A., Deveson, I. W., Duncan, D., Eterovic, A. K., Fan, X., Foox, J., Furlanello, C., Ghosal, A., Glenn, S., Guan, M., Haag, C., Hang, X., Happe, S., Hennigan, B., Hipp, J., Hong, H., Horvath, K., Hu, J., Hung, L. Y., Jarosz, M., Kerkhof, J., Kipp, B., Kreil, D. P., Łabaj, P., Lapunzina, P., Li, P., Li, Q. Z., Li, W., Li, Z., Liang, Y., Liu, S., Liu, Z., Ma, C., Marella, N., Martín-Arenas, R., Megherbi, D. B., Meng, Q., Mieczkowski, P. A., Morrison, T., Muzny, D., Ning, B., Parsons, B. L., Paweletz, C. P., Pirooznia, M., Qu, W., Raymond, A., Rindler, P., Ringler, R., Sadikovic, B., Scherer, A., Schulze, E., Sebra, R., Shaknovich, R., Shi, Q., Shi, T., Silla-Castro, J. C., Smith, M., López, M. S., Song, P., Stetson, D., Strahl, M., Stuart, A., Supplee, J., Szankasi, P., Tan, H., Tang, L. Y., Tao, Y., Thakkar, S., Thierry-Mieg, D., Thierry-Mieg, J., Thodima, V. J., Thomas, D., Tichý, B., Tom, N., Garcia, E. V., Verma, S., Walker, K., Wang, C., Wang, J., Wang, Y., Wen, Z., Wirta, V., Wu, L., Xiao, C., Xiao, W., Xu, S., Yang, M., Ying, J., Yip, S. H., Zhang, G., Zhang, S., Zhao, M., Zheng, Y., Zhou, X., Mason, C. E., Mercer, T., Tong, W., Shi, L., Jones, W. & Xu, J., Dec 2021, In: Genome biology. 22, 1, 109.

    Research output: Contribution to journalArticlepeer-review

    Open Access
  • Doppler-Guided Acoustically Active Injection Catheter: Transendocardial Delivery Assessed by an Efficacy Testing Animal Model

    Katayama, M., Gades, N. M., Singh, V. P., Devick, K. L., Zarbatany, D., Vaitkus, V. V., Belohlavek, D. L., Fortuin, F. D. & Belohlavek, M., 2021, (Accepted/In press) In: Journal of Ultrasound in Medicine.

    Research output: Contribution to journalArticlepeer-review

  • Elevated fibroblast growth factor-inducible 14 expression transforms proneural-like gliomas into more aggressive and lethal brain cancer

    Connolly, N. P., Galisteo, R., Xu, S., Bar, E. E., Peng, S., Tran, N. L., Ames, H. M., Kim, A. J., Woodworth, G. F. & Winkles, J. A., Sep 2021, In: Glia. 69, 9, p. 2199-2214 16 p.

    Research output: Contribution to journalArticlepeer-review

  • Experiences of Latino Participants Receiving Neutral Genomic Screening Results: A Qualitative Study

    Cheema, A. W., Sutton, E. J., Beck, A. T., Cuellar, I., Moreno Garzon, G. G., Hernandez, V., Lindor, N. M., Shaibi, G. Q., Kullo, I. J. & Sharp, R. R., Feb 2021, In: Public health genomics. 24, 1-2, p. 44-53 10 p.

    Research output: Contribution to journalArticlepeer-review

    1 Scopus citations
  • Expression of NrasQ61R and MYC transgene in germinal center B cells induces a highly malignant multiple myeloma in mice

    Wen, Z., Rajagopalan, A., Flietner, E. D., Yun, G., Chesi, M., Furumo, Q., Burns, R. T., Papadas, A., Ranheim, E. A., Pagenkopf, A. C., Morrow, Z. T., Finn, R., Zhou, Y., Li, S., You, X., Jensen, J., Yu, M., Cicala, A., Menting, J., Mitsiades, C. S. & 5 others, Callander, N. S., Leif Bergsagel, P., Wang, D., Asimakopoulos, F. & Zhang, J., Jan 7 2021, In: Blood. 137, 1, p. 61-74 14 p.

    Research output: Contribution to journalArticlepeer-review

    2 Scopus citations
  • Genetic architectures of proximal and distal colorectal cancer are partly distinct

    Huyghe, J. R., Harrison, T. A., Bien, S. A., Hampel, H., Figueiredo, J. C., Schmit, S. L., Conti, D. V., Chen, S., Qu, C., Lin, Y., Barfield, R., Baron, J. A., Cross, A. J., Diergaarde, B., Duggan, D., Harlid, S., Imaz, L., Kang, H. M., Levine, D. M., Perduca, V. & 121 others, Perez-Cornago, A., Sakoda, L. C., Schumacher, F. R., Slattery, M. L., Toland, A. E., Van Duijnhoven, F. J. B., Van Guelpen, B., Agudo, A., Albanes, D., Alonso, M. H., Anderson, K., Arnau-Collell, C., Arndt, V., Banbury, B. L., Bassik, M. C., Berndt, S. I., Bézieau, S., Bishop, D. T., Boehm, J., Boeing, H., Boutron-Ruault, M. C., Brenner, H., Brezina, S., Buch, S., Buchanan, D. D., Burnett-Hartman, A., Caan, B. J., Campbell, P. T., Carr, P. R., Castells, A., Castellví-Bel, S., Chan, A. T., Chang-Claude, J., Chanock, S. J., Curtis, K. R., De La Chapelle, A., Easton, D. F., English, D. R., Feskens, E. J. M., Gala, M., Gallinger, S. J., Gauderman, W. J., Giles, G. G., Goodman, P. J., Grady, W. M., Grove, J. S., Gsur, A., Gunter, M. J., Haile, R. W., Hampe, J., Hoffmeister, M., Hopper, J. L., Hsu, W. L., Huang, W. Y., Hudson, T. J., Jenab, M., Jenkins, M. A., Joshi, A. D., Keku, T. O., Kooperberg, C., Kühn, T., Küry, S., Le Marchand, L., Lejbkowicz, F., Li, C. I., Li, L., Lieb, W., Lindblom, A., Lindor, N. M., Männistö, S., Markowitz, S. D., Milne, R. L., Moreno, L., Murphy, N., Nassir, R., Offit, K., Ogino, S., Panico, S., Parfrey, P. S., Pearlman, R., Pharoah, P. D. P., Phipps, A. I., Platz, E. A., Potter, J. D., Prentice, R. L., Qi, L., Raskin, L., Rennert, G., Rennert, H. S., Riboli, E., Schafmayer, C., Schoen, R. E., Seminara, D., Song, M., Su, Y. R., Tangen, C. M., Thibodeau, S. N., Thomas, D. C., Trichopoulou, A., Ulrich, C. M., Visvanathan, K., Vodicka, P., Vodickova, L., Vymetalkova, V., Weigl, K., Weinstein, S. J., White, E., Wolk, A., Woods, M. O., Wu, A. H., Abecasis, G. R., Nickerson, D. A., Scacheri, P. C., Kundaje, A., Casey, G., Gruber, S. B., Hsu, L., Moreno, V., Hayes, R. B., Newcomb, P. A. & Peters, U., Jul 1 2021, In: Gut. 70, 7, p. 1325-1334 10 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    1 Scopus citations
  • Implication of TIGIT+ human memory B cells in immune regulation

    Hasan, M. M., Nair, S. S., O’Leary, J. G., Thompson-Snipes, L. A., Nyarige, V., Wang, J., Park, W., Stegall, M., Heilman, R., Klintmalm, G. B., Joo, H. M. & Oh, S. K., Dec 2021, In: Nature communications. 12, 1, 1534.

    Research output: Contribution to journalArticlepeer-review

    Open Access
  • Increasing access to individualized medicine: a matched-cohort study examining Latino participant experiences of genomic screening

    Pacyna, J. E., Shaibi, G. Q., Lee, A., Byrne, J. O., Cuellar, I., Sutton, E. J., Hernandez, V., Lindor, N. M., Singh, D., Kullo, I. J. & Sharp, R. R., May 2021, In: Genetics in Medicine. 23, 5, p. 934-941 8 p.

    Research output: Contribution to journalArticlepeer-review

    1 Scopus citations
  • Integrating Genomic Screening into Primary Care: Provider Experiences Caring for Latino Patients at a Community-Based Health Center

    Srinivasan, T., Sutton, E. J., Beck, A. T., Cuellar, I., Hernandez, V., Pacyna, J. E., Shaibi, G. Q., Kullo, I. J., Lindor, N. M., Singh, D. & Sharp, R. R., 2021, In: Journal of Primary Care and Community Health. 12

    Research output: Contribution to journalArticlepeer-review

    Open Access
  • Nanocell-mediated delivery of miR-34a counteracts temozolomide resistance in glioblastoma

    Khan, M. B., Ruggieri, R., Jamil, E., Tran, N. L., Gonzalez, C., Mugridge, N., Gao, S., MacDiarmid, J., Brahmbhatt, H., Sarkaria, J. N., Boockvar, J. & Symons, M., Dec 2021, In: Molecular Medicine. 27, 1, 28.

    Research output: Contribution to journalArticlepeer-review

    Open Access
  • Penetrance and outcomes at 1-year following return of actionable variants identified by genome sequencing

    Lee, C., Elsekaily, O., Kochan, D. C., Alhalabi, L., Faizee, F., Sharp, R., Lindor, N. M. & Kullo, I. J., Jul 2021, In: Genetics in Medicine. 23, 7, p. 1192-1201 10 p.

    Research output: Contribution to journalArticlepeer-review

  • Response to Li and Hopper

    Thomas, M., Sakoda, L. C., Hoffmeister, M., Rosenthal, E. A., Lee, J. K., van Duijnhoven, F. J. B., Platz, E. A., Wu, A. H., Dampier, C. H., de la Chapelle, A., Wolk, A., Joshi, A. D., Burnett-Hartman, A., Gsur, A., Lindblom, A., Castells, A., Win, A. K., Namjou, B., Van Guelpen, B., Tangen, C. M. & 77 others, He, Q., Li, C. I., Schafmayer, C., Joshu, C. E., Ulrich, C. M., Bishop, D. T., Buchanan, D. D., Schaid, D., Drew, D. A., Muller, D. C., Duggan, D., Crosslin, D. R., Albanes, D., Giovannucci, E. L., Larson, E., Qu, F., Mentch, F., Giles, G. G., Hakonarson, H., Hampel, H., Stanaway, I. B., Figueiredo, J. C., Huyghe, J. R., Minnier, J., Chang-Claude, J., Hampe, J., Harley, J. B., Visvanathan, K., Curtis, K. R., Offit, K., Li, L., Le Marchand, L., Vodickova, L., Gunter, M. J., Jenkins, M. A., Slattery, M. L., Lemire, M., Woods, M. O., Song, M., Murphy, N., Lindor, N. M., Dikilitas, O., Pharoah, P. D. P., Campbell, P. T., Newcomb, P. A., Milne, R. L., MacInnis, R. J., Castellví-Bel, S., Ogino, S., Berndt, S. I., Bézieau, S., Thibodeau, S. N., Gallinger, S. J., Zaidi, S. H., Harrison, T. A., Keku, T. O., Hudson, T. J., Vymetalkova, V., Moreno, V., Martín, V., Arndt, V., Wei, W. Q., Chung, W., Su, Y. R., Hayes, R. B., White, E., Vodicka, P., Casey, G., Gruber, S. B., Schoen, R. E., Chan, A. T., Potter, J. D., Brenner, H., Jarvik, G. P., Corley, D. A., Peters, U. & Hsu, L., Mar 4 2021, In: American journal of human genetics. 108, 3, p. 527-529 3 p.

    Research output: Contribution to journalLetterpeer-review

    Open Access
  • Risk-reducing hysterectomy and bilateral salpingo-oophorectomy in female heterozygotes of pathogenic mismatch repair variants: a Prospective Lynch Syndrome Database report

    Dominguez-Valentin, M., Crosbie, E. J., Engel, C., Aretz, S., Macrae, F., Winship, I., Capella, G., Thomas, H., Nakken, S., Hovig, E., Nielsen, M., Sijmons, R. H., Bertario, L., Bonanni, B., Tibiletti, M. G., Cavestro, G. M., Mints, M., Gluck, N., Katz, L., Heinimann, K. & 68 others, Vaccaro, C. A., Green, K., Lalloo, F., Hill, J., Schmiegel, W., Vangala, D., Perne, C., Strauß, H. G., Tecklenburg, J., Holinski-Feder, E., Steinke-Lange, V., Mecklin, J. P., Plazzer, J. P., Pineda, M., Navarro, M., Vidal, J. B., Kariv, R., Rosner, G., Piñero, T. A., Gonzalez, M. L., Kalfayan, P., Ryan, N., ten Broeke, S. W., Jenkins, M. A., Sunde, L., Bernstein, I., Burn, J., Greenblatt, M., de Vos tot Nederveen Cappel, W. H., Della Valle, A., Lopez-Koestner, F., Alvarez, K., Büttner, R., Görgens, H., Morak, M., Holzapfel, S., Hüneburg, R., von Knebel Doeberitz, M., Loeffler, M., Rahner, N., Weitz, J., Pylvänäinen, K., Renkonen-Sinisalo, L., Lepistö, A., Auranen, A., Hopper, J. L., Win, A. K., Haile, R. W., Lindor, N. M., Gallinger, S., Le Marchand, L., Newcomb, P. A., Figueiredo, J. C., Thibodeau, S. N., Therkildsen, C., Okkels, H., Ketabi, Z., Denton, O. G., Rødland, E. A., Vasen, H., Neffa, F., Esperon, P., Tjandra, D., Möslein, G., Sampson, J. R., Evans, D. G., Seppälä, T. T. & Møller, P., Apr 2021, In: Genetics in Medicine. 23, 4, p. 705-712 8 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    1 Scopus citations
  • Uncertainty quantification in the radiogenomics modeling of EGFR amplification in glioblastoma

    Hu, L. S., Wang, L., Hawkins-Daarud, A., Eschbacher, J. M., Singleton, K. W., Jackson, P. R., Clark-Swanson, K., Sereduk, C. P., Peng, S., Wang, P., Wang, J., Baxter, L. C., Smith, K. A., Mazza, G. L., Stokes, A. M., Bendok, B. R., Zimmerman, R. S., Krishna, C., Porter, A. B., Mrugala, M. M. & 5 others, Hoxworth, J. M., Wu, T., Tran, N. L., Swanson, K. R. & Li, J., Dec 2021, In: Scientific reports. 11, 1, 3932.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    1 Scopus citations
  • Uptake of hysterectomy and bilateral salpingo-oophorectomy in carriers of pathogenic mismatch repair variants: a Prospective Lynch Syndrome Database report

    Seppälä, T. T., Dominguez-Valentin, M., Crosbie, E. J., Engel, C., Aretz, S., Macrae, F., Winship, I., Capella, G., Thomas, H., Hovig, E., Nielsen, M., Sijmons, R. H., Bertario, L., Bonanni, B., Tibiletti, M. G., Cavestro, G. M., Mints, M., Gluck, N., Katz, L., Heinimann, K. & 66 others, Vaccaro, C. A., Green, K., Lalloo, F., Hill, J., Schmiegel, W., Vangala, D., Perne, C., Strauß, H. G., Tecklenburg, J., Holinski-Feder, E., Steinke-Lange, V., Mecklin, J. P., Plazzer, J. P., Pineda, M., Navarro, M., Vida, J. B., Kariv, R., Rosner, G., Piñero, T. A., Pavicic, W., Kalfayan, P., ten Broeke, S. W., Jenkins, M. A., Sunde, L., Bernstein, I., Burn, J., Greenblatt, M., de Vos tot Nederveen Cappel, W. H., Della Valle, A., Lopez-Koestner, F., Alvarez, K., Büttner, R., Görgens, H., Morak, M., Holzapfel, S., Hüneburg, R., von Knebel Doeberitz, M., Loeffler, M., Redler, S., Weitz, J., Pylvänäinen, K., Renkonen-Sinisalo, L., Lepistö, A., Hopper, J. L., Win, A. K., Lindor, N. M., Gallinger, S., Le Marchand, L., Newcomb, P. A., Figueiredo, J. C., Thibodeau, S. N., Therkildsen, C., Wadt, K. A. W., Mourits, M. J. E., Ketabi, Z., Denton, O. G., Rødland, E. A., Vasen, H., Neffa, F., Esperon, P., Tjandra, D., Möslein, G., Rokkones, E., Sampson, J. R., Evans, D. G. & Møller, P., May 2021, In: European Journal of Cancer. 148, p. 124-133 10 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
  • 2020

    ADAM10 mediates ectopic proximal tubule development and renal fibrosis through Notch signalling

    Li, B., Zhu, C., Dong, L., Qin, J., Xiang, W., Davidson, A. J., Feng, S., Wang, Y., Shen, X., Weng, C., Wang, C., Zhu, T., Teng, L., Wang, J., Englert, C., Chen, J. & Jiang, H., Nov 1 2020, In: Journal of Pathology. 252, 3, p. 274-289 16 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    1 Scopus citations
  • A Deep Convolutional Neural Network for Annotation of Magnetic Resonance Imaging Sequence Type

    Ranjbar, S., Singleton, K. W., Jackson, P. R., Rickertsen, C. R., Whitmire, S. A., Clark-Swanson, K. R., Mitchell, J. R., Swanson, K. R. & Hu, L. S., Apr 1 2020, In: Journal of Digital Imaging. 33, 2, p. 439-446 8 p.

    Research output: Contribution to journalArticlepeer-review

    1 Scopus citations
  • A general framework for functionally informed set-based analysis: Application to a large-scale colorectal cancer study

    Dong, X., Su, Y. R., Barfield, R., Bien, S. A., He, Q., Harrison, T. A., Huyghe, J. R., Keku, T. O., Lindor, N. M., Schafmayer, C., Chan, A. T., Gruber, S. B., Jenkins, M. A., Kooperberg, C., Peters, U. & Hsu, L., Aug 24 2020, In: PLoS genetics. 16, 8, e1008947.

    Research output: Contribution to journalArticlepeer-review

    Open Access
  • A hybrid echocardiography-CFD framework for ventricular flow simulations

    Hedayat, M., Patel, T. R., Kim, T., Belohlavek, M., Hoffmann, K. R. & Borazjani, I., Jul 1 2020, In: International Journal for Numerical Methods in Biomedical Engineering. 36, 7, e03352.

    Research output: Contribution to journalArticlepeer-review

    2 Scopus citations
  • A new comprehensive colorectal cancer risk prediction model incorporating family history, personal characteristics, and environmental factors

    Zheng, Y., Hua, X., Win, A. K., MacInnis, R. J., Gallinger, S., Le Marchand, L., Lindor, N. M., Baron, J. A., Hopper, J. L., Dowty, J. G., Antoniou, A. C., Zheng, J., Jenkins, M. A. & Newcomb, P. A., 2020, In: Cancer Epidemiology Biomarkers and Prevention. 29, 3, p. 549-557 9 p.

    Research output: Contribution to journalArticlepeer-review

    4 Scopus citations
  • Author Correction: Combination of ERK and autophagy inhibition as a treatment approach for pancreatic cancer (Nature Medicine, (2019), 25, 4, (628-640), 10.1038/s41591-019-0368-8)

    Bryant, K. L., Stalnecker, C. A., Zeitouni, D., Klomp, J. E., Peng, S., Tikunov, A. P., Gunda, V., Pierobon, M., Waters, A. M., George, S. D., Tomar, G., Papke, B., Hobbs, G. A., Yan, L., Hayes, T. K., Diehl, J. N., Goode, G. D., Chaika, N. V., Wang, Y., Zhang, G. F. & 11 others, Witkiewicz, A. K., Knudsen, E. S., Petricoin, E. F., Singh, P. K., Macdonald, J. M., Tran, N. L., Lyssiotis, C. A., Ying, H., Kimmelman, A. C., Cox, A. D. & Der, C. J., Jun 1 2020, In: Nature Medicine. 26, 6, p. 982 1 p.

    Research output: Contribution to journalComment/debatepeer-review

    Open Access
    1 Scopus citations
  • Cancer risks by gene, age, and gender in 6350 carriers of pathogenic mismatch repair variants: findings from the Prospective Lynch Syndrome Database

    Dominguez-Valentin, M., Sampson, J. R., Seppälä, T. T., ten Broeke, S. W., Plazzer, J. P., Nakken, S., Engel, C., Aretz, S., Jenkins, M. A., Sunde, L., Bernstein, I., Capella, G., Balaguer, F., Thomas, H., Evans, D. G., Burn, J., Greenblatt, M., Hovig, E., de Vos tot Nederveen Cappel, W. H., Sijmons, R. H. & 68 others, Bertario, L., Tibiletti, M. G., Cavestro, G. M., Lindblom, A., Della Valle, A., Lopez-Köstner, F., Gluck, N., Katz, L. H., Heinimann, K., Vaccaro, C. A., Büttner, R., Görgens, H., Holinski-Feder, E., Morak, M., Holzapfel, S., Hüneburg, R., Knebel Doeberitz, M. V., Loeffler, M., Rahner, N., Schackert, H. K., Steinke-Lange, V., Schmiegel, W., Vangala, D., Pylvänäinen, K., Renkonen-Sinisalo, L., Hopper, J. L., Win, A. K., Haile, R. W., Lindor, N. M., Gallinger, S., Le Marchand, L., Newcomb, P. A., Figueiredo, J. C., Thibodeau, S. N., Wadt, K., Therkildsen, C., Okkels, H., Ketabi, Z., Moreira, L., Sánchez, A., Serra-Burriel, M., Pineda, M., Navarro, M., Blanco, I., Green, K., Lalloo, F., Crosbie, E. J., Hill, J., Denton, O. G., Frayling, I. M., Rødland, E. A., Vasen, H., Mints, M., Neffa, F., Esperon, P., Alvarez, K., Kariv, R., Rosner, G., Pinero, T. A., Gonzalez, M. L., Kalfayan, P., Tjandra, D., Winship, I. M., Macrae, F., Möslein, G., Mecklin, J. P., Nielsen, M. & Møller, P., Jan 1 2020, In: Genetics in Medicine. 22, 1, p. 15-25 11 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    79 Scopus citations
  • Challenges in returning results in a genomic medicine implementation study: the Return of Actionable Variants Empirical (RAVE) study

    Kochan, D. C., Winkler, E., Lindor, N., Shaibi, G. Q., Olson, J., Caraballo, P. J., Freimuth, R., Pacyna, J. E., Breitkopf, C. R., Sharp, R. R. & Kullo, I. J., Dec 1 2020, In: npj Genomic Medicine. 5, 1, 19.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    2 Scopus citations
  • Circulating bilirubin levels and risk of colorectal cancer: Serological and Mendelian randomization analyses

    Seyed Khoei, N., Jenab, M., Murphy, N., Banbury, B. L., Carreras-Torres, R., Viallon, V., Kühn, T., Bueno-De-Mesquita, B., Aleksandrova, K., Cross, A. J., Weiderpass, E., Stepien, M., Bulmer, A., Tjønneland, A., Boutron-Ruault, M. C., Severi, G., Carbonnel, F., Katzke, V., Boeing, H., Bergmann, M. M. & 78 others, Trichopoulou, A., Karakatsani, A., Martimianaki, G., Palli, D., Tagliabue, G., Panico, S., Tumino, R., Sacerdote, C., Skeie, G., Merino, S., Bonet, C., Rodríguez-Barranco, M., Gil, L., Chirlaque, M. D., Ardanaz, E., Myte, R., Hultdin, J., Perez-Cornago, A., Aune, D., Tsilidis, K. K., Albanes, D., Baron, J. A., Berndt, S. I., Bézieau, S., Brenner, H., Campbell, P. T., Casey, G., Chan, A. T., Chang-Claude, J., Chanock, S. J., Cotterchio, M., Gallinger, S., Gruber, S. B., Haile, R. W., Hampe, J., Hoffmeister, M., Hopper, J. L., Hsu, L., Huyghe, J. R., Jenkins, M. A., Joshi, A. D., Kampman, E., Larsson, S. C., Le Marchand, L., Li, C. I., Li, L., Lindblom, A., Lindor, N. M., Martín, V., Moreno, V., Newcomb, P. A., Offit, K., Ogino, S., Parfrey, P. S., Pharoah, P. D. P., Rennert, G., Sakoda, L. C., Schafmayer, C., Schmit, S. L., Schoen, R. E., Slattery, M. L., Thibodeau, S. N., Ulrich, C. M., Van Duijnhoven, F. J. B., Weigl, K., Weinstein, S. J., White, E., Wolk, A., Woods, M. O., Wu, A. H., Zhang, X., Ferrari, P., Anton, G., Peters, A., Peters, U., Gunter, M. J., Wagner, K. H. & Freisling, H., Sep 3 2020, In: BMC Medicine. 18, 1, 229.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    4 Scopus citations
  • Contribution of mRNA Splicing to Mismatch Repair Gene Sequence Variant Interpretation

    the InSiGHT Variant Interpretation Committee, Jul 27 2020, In: Frontiers in Genetics. 11, 798.

    Research output: Contribution to journalArticlepeer-review

    Open Access
  • Correction: Cancer risks by gene, age, and gender in 6350 carriers of pathogenic mismatch repair variants: findings from the Prospective Lynch Syndrome Database (Genetics in Medicine, (2020), 22, 1, (15-25), 10.1038/s41436-019-0596-9)

    Dominguez-Valentin, M., Sampson, J. R., Seppälä, T. T., ten Broeke, S. W., Plazzer, J. P., Nakken, S., Engel, C., Aretz, S., Jenkins, M. A., Sunde, L., Bernstein, I., Capella, G., Balaguer, F., Thomas, H., Evans, D. G., Burn, J., Greenblatt, M., Hovig, E., de Vos tot Nederveen Cappel, W. H., Sijmons, R. H. & 68 others, Bertario, L., Tibiletti, M. G., Cavestro, G. M., Lindblom, A., Della Valle, A., Lopez-Köstner, F., Gluck, N., Katz, L. H., Heinimann, K., Vaccaro, C. A., Büttner, R., Görgens, H., Holinski-Feder, E., Morak, M., Holzapfel, S., Hüneburg, R., Knebel Doeberitz, M. V., Loeffler, M., Rahner, N., Schackert, H. K., Steinke-Lange, V., Schmiegel, W., Vangala, D., Pylvänäinen, K., Renkonen-Sinisalo, L., Hopper, J. L., Win, A. K., Haile, R. W., Lindor, N. M., Gallinger, S., Le Marchand, L., Newcomb, P. A., Figueiredo, J. C., Thibodeau, S. N., Wadt, K., Therkildsen, C., Okkels, H., Ketabi, Z., Moreira, L., Sánchez, A., Serra-Burriel, M., Pineda, M., Navarro, M., Blanco, I., Green, K., Lalloo, F., Crosbie, E. J., Hill, J., Denton, O. G., Frayling, I. M., Rødland, E. A., Vasen, H., Mints, M., Neffa, F., Esperon, P., Alvarez, K., Kariv, R., Rosner, G., Pinero, T. A., Gonzalez, M. L., Kalfayan, P., Tjandra, D., Winship, I. M., Macrae, F., Möslein, G., Mecklin, J. P., Nielsen, M. & Møller, P., Sep 1 2020, In: Genetics in Medicine. 22, 9, p. 1569 1 p.

    Research output: Contribution to journalComment/debatepeer-review

    Open Access
  • Cumulative Burden of Colorectal Cancer–Associated Genetic Variants Is More Strongly Associated With Early-Onset vs Late-Onset Cancer

    Archambault, A. N., Su, Y. R., Jeon, J., Thomas, M., Lin, Y., Conti, D. V., Win, A. K., Sakoda, L. C., Lansdorp-Vogelaar, I., Peterse, E. F. P., Zauber, A. G., Duggan, D., Holowatyj, A. N., Huyghe, J. R., Brenner, H., Cotterchio, M., Bézieau, S., Schmit, S. L., Edlund, C. K., Southey, M. C. & 114 others, MacInnis, R. J., Campbell, P. T., Chang-Claude, J., Slattery, M. L., Chan, A. T., Joshi, A. D., Song, M., Cao, Y., Woods, M. O., White, E., Weinstein, S. J., Ulrich, C. M., Hoffmeister, M., Bien, S. A., Harrison, T. A., Hampe, J., Li, C. I., Schafmayer, C., Offit, K., Pharoah, P. D., Moreno, V., Lindblom, A., Wolk, A., Wu, A. H., Li, L., Gunter, M. J., Gsur, A., Keku, T. O., Pearlman, R., Bishop, D. T., Castellví-Bel, S., Moreira, L., Vodicka, P., Kampman, E., Giles, G. G., Albanes, D., Baron, J. A., Berndt, S. I., Brezina, S., Buch, S., Buchanan, D. D., Trichopoulou, A., Severi, G., Chirlaque, M. D., Sánchez, M. J., Palli, D., Kühn, T., Murphy, N., Cross, A. J., Burnett-Hartman, A. N., Chanock, S. J., de la Chapelle, A., Easton, D. F., Elliott, F., English, D. R., Feskens, E. J. M., FitzGerald, L. M., Goodman, P. J., Hopper, J. L., Hudson, T. J., Hunter, D. J., Jacobs, E. J., Joshu, C. E., Küry, S., Markowitz, S. D., Milne, R. L., Platz, E. A., Rennert, G., Rennert, H. S., Schumacher, F. R., Sandler, R. S., Seminara, D., Tangen, C. M., Thibodeau, S. N., Toland, A. E., van Duijnhoven, F. J. B., Visvanathan, K., Vodickova, L., Potter, J. D., Männistö, S., Weigl, K., Figueiredo, J., Martín, V., Larsson, S. C., Parfrey, P. S., Huang, W. Y., Lenz, H. J., Castelao, J. E., Gago-Dominguez, M., Muñoz-Garzón, V., Mancao, C., Haiman, C. A., Wilkens, L. R., Siegel, E., Barry, E., Younghusband, B., Van Guelpen, B., Harlid, S., Zeleniuch-Jacquotte, A., Liang, P. S., Du, M., Casey, G., Lindor, N. M., Le Marchand, L., Gallinger, S. J., Jenkins, M. A., Newcomb, P. A., Gruber, S. B., Schoen, R. E., Hampel, H., Corley, D. A., Hsu, L., Peters, U. & Hayes, R. B., Apr 2020, In: Gastroenterology. 158, 5, p. 1274-1286.e12

    Research output: Contribution to journalArticlepeer-review

    21 Scopus citations
  • Decreased nonspecific adhesivity, receptor-targeted therapeutic nanoparticles for primary and metastatic breast cancer

    Dancy, J. G., Wadajkar, A. S., Connolly, N. P., Galisteo, R., Ames, H. M., Peng, S., Tran, N. L., Goloubeva, O. G., Woodworth, G. F., Winkles, J. A. & Kim, A. J., 2020, In: Science Advances. 6, 3, eaax3931.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    16 Scopus citations
  • DNA repair and cancer in colon and rectum: Novel players in genetic susceptibility

    Pardini, B., Corrado, A., Paolicchi, E., Cugliari, G., Berndt, S. I., Bezieau, S., Bien, S. A., Brenner, H., Caan, B. J., Campbell, P. T., Casey, G., Chan, A. T., Chang-Claude, J., Cotterchio, M., Gala, M., Gallinger, S. J., Haile, R. W., Harrison, T. A., Hayes, R. B., Hoffmeister, M. & 21 others, Hopper, J. L., Hsu, L., Huyghe, J., Jenkins, M. A., Le Marchand, L., Lin, Y., Lindor, N. M., Nan, H., Newcomb, P. A., Ogino, S., Potter, J. D., Schoen, R. E., Slattery, M. L., White, E., Vodickova, L., Vymetalkova, V., Vodicka, P., Gemignani, F., Peters, U., Naccarati, A. & Landi, S., Jan 15 2020, In: International Journal of Cancer. 146, 2, p. 363-372 10 p.

    Research output: Contribution to journalArticlepeer-review

    7 Scopus citations
  • Do the risks of Lynch syndrome-related cancers depend on the parent of origin of the mutation?

    Gemechu, S. D., van Vliet, C. M., Win, A. K., Figueiredo, J. C., Le Marchand, L., Gallinger, S., Newcomb, P. A., Hopper, J. L., Lindor, N. M., Jenkins, M. A. & Dowty, J. G., Jul 1 2020, In: Familial Cancer. 19, 3, p. 215-222 8 p.

    Research output: Contribution to journalArticlepeer-review

    1 Scopus citations
  • Dynamic CD138 surface expression regulates switch between myeloma growth and dissemination

    Akhmetzyanova, I., McCarron, M. J., Parekh, S., Chesi, M., Bergsagel, P. L. & Fooksman, D. R., Jan 1 2020, In: Leukemia. 34, 1, p. 245-256 12 p.

    Research output: Contribution to journalArticlepeer-review

    10 Scopus citations
  • Erratum: Tacrolimus dose requirement based on the CYP3A5 genotype in renal transplant patients (Oncotarget (2017) 8 (81285-81294) DOI: 10.18632/oncotarget.18150)

    Qu, L., Lu, Y., Ying, M., Li, B., Weng, C., Xie, Z., Liang, L., Lin, C., Yang, X., Feng, S., Wang, Y., Shen, X., Zhou, Q., Chen, Y., Chen, Z., Wu, J., Lin, W., Shen, Y., Qin, J., Xu, H. & 5 others, Xu, F., Wang, J., Chen, J., Jiang, H. & Huang, H., Apr 21 2020, In: Oncotarget. 11, 16, p. 1474-1477 4 p.

    Research output: Contribution to journalComment/debatepeer-review

  • Functional informed genome-wide interaction analysis of body mass index, diabetes and colorectal cancer risk

    Xia, Z., Su, Y. R., Petersen, P., Qi, L., Kim, A. E., Figueiredo, J. C., Lin, Y., Nan, H., Sakoda, L. C., Albanes, D., Berndt, S. I., Bézieau, S., Bien, S., Buchanan, D. D., Casey, G., Chan, A. T., Conti, D. V., Drew, D. A., Gallinger, S. J., Gauderman, W. J. & 29 others, Giles, G. G., Gruber, S. B., Gunter, M. J., Hoffmeister, M., Jenkins, M. A., Joshi, A. D., Le Marchand, L., Lewinger, J. P., Li, L., Lindor, N. M., Moreno, V., Murphy, N., Nassir, R., Newcomb, P. A., Ogino, S., Rennert, G., Song, M., Wang, X., Wolk, A., Woods, M. O., Brenner, H., White, E., Slattery, M. L., Giovannucci, E. L., Chang-Claude, J., Pharoah, P. D. P., Hsu, L., Campbell, P. T. & Peters, U., May 1 2020, In: Cancer medicine. 9, 10, p. 3563-3573 11 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    3 Scopus citations
  • Genome-wide DNA methylation analysis of KRAS mutant cell lines

    Tew, B. Y., Durand, J. K., Bryant, K. L., Hayes, T. K., Peng, S., Tran, N. L., Gooden, G. C., Buckley, D. N., Der, C. J., Baldwin, A. S. & Salhia, B., Dec 1 2020, In: Scientific reports. 10, 1, 10149.

    Research output: Contribution to journalArticlepeer-review

    Open Access
  • Genome-wide Modeling of Polygenic Risk Score in Colorectal Cancer Risk

    Thomas, M., Sakoda, L. C., Hoffmeister, M., Rosenthal, E. A., Lee, J. K., van Duijnhoven, F. J. B., Platz, E. A., Wu, A. H., Dampier, C. H., de la Chapelle, A., Wolk, A., Joshi, A. D., Burnett-Hartman, A., Gsur, A., Lindblom, A., Castells, A., Win, A. K., Namjou, B., Van Guelpen, B., Tangen, C. M. & 77 others, He, Q., Li, C. I., Schafmayer, C., Joshu, C. E., Ulrich, C. M., Bishop, D. T., Buchanan, D. D., Schaid, D., Drew, D. A., Muller, D. C., Duggan, D., Crosslin, D. R., Albanes, D., Giovannucci, E. L., Larson, E., Qu, F., Mentch, F., Giles, G. G., Hakonarson, H., Hampel, H., Stanaway, I. B., Figueiredo, J. C., Huyghe, J. R., Minnier, J., Chang-Claude, J., Hampe, J., Harley, J. B., Visvanathan, K., Curtis, K. R., Offit, K., Li, L., Le Marchand, L., Vodickova, L., Gunter, M. J., Jenkins, M. A., Slattery, M. L., Lemire, M., Woods, M. O., Song, M., Murphy, N., Lindor, N. M., Dikilitas, O., Pharoah, P. D. P., Campbell, P. T., Newcomb, P. A., Milne, R. L., MacInnis, R. J., Castellví-Bel, S., Ogino, S., Berndt, S. I., Bézieau, S., Thibodeau, S. N., Gallinger, S. J., Zaidi, S. H., Harrison, T. A., Keku, T. O., Hudson, T. J., Vymetalkova, V., Moreno, V., Martín, V., Arndt, V., Wei, W. Q., Chung, W., Su, Y. R., Hayes, R. B., White, E., Vodicka, P., Casey, G., Gruber, S. B., Schoen, R. E., Chan, A. T., Potter, J. D., Brenner, H., Jarvik, G. P., Corley, D. A., Peters, U. & Hsu, L., Sep 3 2020, In: American journal of human genetics. 107, 3, p. 432-444 13 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    6 Scopus citations
  • Genomic and phenotypic characterization of a broad panel of patient-derived xenografts reflects the diversity of glioblastoma

    Vaubel, R. A., Tian, S., Remonde, D., Schroeder, M. A., Mladek, A. C., Kitange, G. J., Caron, A., Kollmeyer, T. M., Grove, R., Peng, S., Carlson, B. L., Ma, D. J., Sarkar, G., Evers, L., Decker, P. A., Yan, H., Dhruv, H. D., Berens, M. E., Wang, Q., Marin, B. M. & 14 others, Klee, E. W., Califano, A., LaChance, D. H., Eckel-Passow, J. E., Verhaak, R. G., Sulman, E. P., Burns, T. C., Meyer, F. B., O'Neill, B. P., Tran, N. L., Giannini, C., Jenkins, R. B., Parney, I. F. & Sarkaria, J. N., Mar 1 2020, In: Clinical Cancer Research. 26, 5, p. 1094-1104 11 p.

    Research output: Contribution to journalArticlepeer-review

    16 Scopus citations
  • Identification of a blood-based protein biomarker panel for lung cancer detection

    El-Khoury, V., Schritz, A., Kim, S. Y., Lesur, A., Sertamo, K., Bernardin, F., Petritis, K., Pirrotte, P., Selinsky, C., Whiteaker, J. R., Zhang, H., Kennedy, J. J., Lin, C., Lee, L. W., Yan, P., Tran, N. L., Inge, L. J., Chalabi, K., Decker, G., Bjerkvig, R. & 3 others, Paulovich, A. G., Berchem, G. & Kim, Y. J., Jun 2020, In: Cancers. 12, 6, p. 1-15 15 p., 1629.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    1 Scopus citations
  • Identification of PIKfyve kinase as a target in multiple myeloma

    De Campos, C. B., Zhu, Y. X., Sepetov, N., Romanov, S., Bruins, L. A., Shi, C. X., Stein, C. K., Petit, J. L., Polito, A. N., Sharik, M. E., Meermeier, E. W., Ahmann, G. J., Armenta, I. D. L., Kruse, J., Bergsagel, P. L., Chesi, M., Meurice, N., Braggio, E. & Stewart, A. K., Jun 1 2020, In: Haematologica. 105, 6, p. 1641-1649 9 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    5 Scopus citations
  • Identifying the spatial and temporal dynamics of molecularly-distinct glioblastoma sub-populations

    Morris, B., Curtin, L., Hawkins-Daarud, A., Hubbard, M. E., Rahman, R., Smith, S. J., Auer, D., Tran, N. L., Hu, L. S., Eschbacher, J. M., Smith, K. A., Stokes, A., Swanson, K. R. & Owen, M. R., Jul 16 2020, In: Mathematical Biosciences and Engineering. 17, 5, p. 4905-4941 37 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
  • Integrating Convolutional Neural Networks and Multi-Task Dictionary Learning for Cognitive Decline Prediction with Longitudinal Images

    Alzheimer’s Disease Neuroimaging Initiative, 2020, In: Journal of Alzheimer's Disease. 75, 3, p. 971-992 22 p.

    Research output: Contribution to journalArticlepeer-review

    4 Scopus citations
  • Leukemia-Associated Rho Guanine Nucleotide Exchange Factor and Ras Homolog Family Member C Play a Role in Glioblastoma Cell Invasion and Resistance

    Ding, Z., Dong, Z., Yang, Y., Fortin Ensign, S. P., Sabit, H., Nakada, M., Ruggieri, R., Kloss, J. M., Symons, M., Tran, N. L. & Loftus, J. C., Oct 2020, In: American Journal of Pathology. 190, 10, p. 2165-2176 12 p.

    Research output: Contribution to journalArticlepeer-review

    1 Scopus citations
  • Localized metabolomic gradients in patient-derived xenograft models of glioblastoma

    Randall, E. C., Lopez, B. G. C., Peng, S., Regan, M. S., Abdelmoula, W. M., Basu, S. S., Santagata, S., Yoon, H., Haigis, M. C., Agar, J. N., Tran, N. L., Elmquist, W. F., White, F. M., Sarkaria, J. N. & Agar, N. Y. R., Mar 15 2020, In: Cancer research. 80, 6, p. 1258-1267 10 p.

    Research output: Contribution to journalArticlepeer-review

    11 Scopus citations
  • Low-Dose Vertical Inhibition of the RAF-MEK-ERK Cascade Causes Apoptotic Death of KRAS Mutant Cancers

    Ozkan-Dagliyan, I., Diehl, J. N., George, S. D., Schaefer, A., Papke, B., Klotz-Noack, K., Waters, A. M., Goodwin, C. M., Gautam, P., Pierobon, M., Peng, S., Gilbert, T. S. K., Lin, K. H., Dagliyan, O., Wennerberg, K., Petricoin, E. F., Tran, N. L., Bhagwat, S. V., Tiu, R. V., Peng, S. B. & 6 others, Herring, L. E., Graves, L. M., Sers, C., Wood, K. C., Cox, A. D. & Der, C. J., Jun 16 2020, In: Cell reports. 31, 11, 107764.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    6 Scopus citations
  • Methods and resources to access mutation-dependent effects on cancer drug treatment

    Yao, H., Liang, Q., Qian, X., Wang, J., Sham, P. C. & Li, M. J., Nov 1 2020, In: Briefings in bioinformatics. 21, 6, p. 1886-1903 18 p.

    Research output: Contribution to journalArticlepeer-review

  • MYC dysregulation in the progression of multiple myeloma

    MMRF CoMMpass Network, Jan 1 2020, In: Leukemia. 34, 1, p. 322-326 5 p.

    Research output: Contribution to journalLetterpeer-review

    24 Scopus citations
  • Physical activity and risks of breast and colorectal cancer: a Mendelian randomisation analysis

    Papadimitriou, N., Dimou, N., Tsilidis, K. K., Banbury, B., Martin, R. M., Lewis, S. J., Kazmi, N., Robinson, T. M., Albanes, D., Aleksandrova, K., Berndt, S. I., Timothy Bishop, D., Brenner, H., Buchanan, D. D., Bueno-de-Mesquita, B., Campbell, P. T., Castellví-Bel, S., Chan, A. T., Chang-Claude, J., Ellingjord-Dale, M. & 62 others, Figueiredo, J. C., Gallinger, S. J., Giles, G. G., Giovannucci, E., Gruber, S. B., Gsur, A., Hampe, J., Hampel, H., Harlid, S., Harrison, T. A., Hoffmeister, M., Hopper, J. L., Hsu, L., María Huerta, J., Huyghe, J. R., Jenkins, M. A., Keku, T. O., Kühn, T., La Vecchia, C., Le Marchand, L., Li, C. I., Li, L., Lindblom, A., Lindor, N. M., Lynch, B., Markowitz, S. D., Masala, G., May, A. M., Milne, R., Monninkhof, E., Moreno, L., Moreno, V., Newcomb, P. A., Offit, K., Perduca, V., Pharoah, P. D. P., Platz, E. A., Potter, J. D., Rennert, G., Riboli, E., Sánchez, M. J., Schmit, S. L., Schoen, R. E., Severi, G., Sieri, S., Slattery, M. L., Song, M., Tangen, C. M., Thibodeau, S. N., Travis, R. C., Trichopoulou, A., Ulrich, C. M., van Duijnhoven, F. J. B., Van Guelpen, B., Vodicka, P., White, E., Wolk, A., Woods, M. O., Wu, A. H., Peters, U., Gunter, M. J. & Murphy, N., Dec 1 2020, In: Nature communications. 11, 1, 597.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    18 Scopus citations
  • Potential impact of family history–based screening guidelines on the detection of early-onset colorectal cancer

    Gupta, S., Bharti, B., Ahnen, D. J., Buchanan, D. D., Cheng, I. C., Cotterchio, M., Figueiredo, J. C., Gallinger, S. J., Haile, R. W., Jenkins, M. A., Lindor, N. M., Macrae, F. A., Le Marchand, L., Newcomb, P. A., Thibodeau, S. N., Win, A. K. & Martinez, M. E., Jul 1 2020, In: Cancer. 126, 13, p. 3013-3020 8 p.

    Research output: Contribution to journalArticlepeer-review

    8 Scopus citations
  • Returning genomic results in a Federally Qualified Health Center: the intersection of precision medicine and social determinants of health

    Shaibi, G. Q., Kullo, I. J., Singh, D. P., Hernandez, V., Sharp, R. R., Cuellar, I., De Filippis, E., Levey, S., Breitkopf, C. R., Mandarino, L. J., Yang, P., Thibodeau, S. N. & Lindor, N. M., Sep 1 2020, In: Genetics in Medicine. 22, 9, p. 1552-1559 8 p.

    Research output: Contribution to journalArticlepeer-review

    6 Scopus citations