Research Output 1991 2019

2019

Accurate patient-specific machine learning models of glioblastoma invasion using transfer learning

Hu, L. S., Yoon, H., Eschbacher, J. M., Baxter, L. C., Dueck, A. C., Nespodzany, A., Smith, K. A., Nakaji, P., Xu, Y., Wang, L., Karis, J. P., Hawkins-Daarud, A. J., Singleton, K. W., Jackson, P. R., Anderies, B. J., Bendok, B. R., Zimmerman, R. S., Quarles, C., Porter-Umphrey, A. B., Mrugala, M. M. & 11 others, Sharma, A., Hoxworth, J. M., Sattur, M. G., Sanai, N., Koulemberis, P. E., Krishna, C., Mitchell, J. R., Wu, T., Tran, N. L., Swanson, K. R. & Li, J., Jan 1 2019, In : American Journal of Neuroradiology. 40, 3, p. 418-425 8 p.

Research output: Contribution to journalArticle

Open Access
Glioblastoma
Cell Count
Neoplasms
Image-Guided Biopsy
Diffusion Tensor Imaging
1 Citation (Scopus)

A real-time color doppler marker for echocardiographic guidance of an acoustically active extracorporeal membrane oxygenation cannula

Belohlavek, M., Katayama, M., Vaitkus, V. V., Kumar, V., Fatemi, M., Grabham, J. & Sandweiss, B., Jan 1 2019, In : Journal of Ultrasound in Medicine. 38, 7, p. 1875-1885 11 p.

Research output: Contribution to journalArticle

Extracorporeal Membrane Oxygenation
Color
Artifacts
Noise
Ultrasonography
7 Citations (Scopus)

Bone marrow transplantation generates T cell-dependent control of myeloma in mice

Vuckovic, S., Minnie, S. A., Smith, D., Gartlan, K. H., Watkins, T. S., Markey, K. A., Mukhopadhyay, P., Guillerey, C., Kuns, R. D., Locke, K. R., Pritchard, A. L., Johansson, P. A., Varelias, A., Zhang, P., Huntington, N. D., Waddell, N., Chesi, M., Miles, J. J., Smyth, M. J. & Hill, G. R., Jan 2 2019, In : Journal of Clinical Investigation. 129, 1, CI98888.

Research output: Contribution to journalArticle

Bone Marrow Transplantation
T-Lymphocytes
Autologous Transplantation
Tissue Donors
Multiple Myeloma
1 Citation (Scopus)

Chemotherapy followed by anti-CD137 mAb immunotherapy improves disease control in a mouse myeloma model

Guillerey, C., Nakamura, K., Pichler, A. C., Barkauskas, D., Krumeich, S., Stannard, K., Miles, K., Harjunpää, H., Yu, Y., Casey, M., Doban, A. I., Lazar, M., Hartel, G., Smith, D., Vuckovic, S., Teng, M. W. L., Bergsagel, P. L., Chesi, M., Hill, G. R., Martinet, L. & 1 others, Smyth, M. J., Jul 25 2019, In : JCI Insight. 4, 14, :e125932.

Research output: Contribution to journalArticle

Open Access
Multiple Myeloma
Immunotherapy
Drug Therapy
T-Lymphocytes
Therapeutics
41 Citations (Scopus)

Combination of ERK and autophagy inhibition as a treatment approach for pancreatic cancer

Bryant, K. L., Stalnecker, C. A., Zeitouni, D., Klomp, J. E., Peng, S., Tikunov, A. P., Gunda, V., Pierobon, M., Waters, A. M., George, S. D., Tomar, G., Papke, B., Hobbs, G. A., Yan, L., Hayes, T. K., Diehl, J. N., Goode, G. D., Chaika, N. V., Wang, Y., Zhang, G. F. & 11 others, Witkiewicz, A. K., Knudsen, E. S., Petricoin, E. F., Singh, P. K., Macdonald, J. M., Tran, N., Lyssiotis, C. A., Ying, H., Kimmelman, A. C., Cox, A. D. & Der, C. J., Apr 1 2019, In : Nature Medicine. 25, 4, p. 628-640 13 p.

Research output: Contribution to journalArticle

Autophagy
Chloroquine
Pancreatic Neoplasms
Fluxes
Adenocarcinoma
1 Citation (Scopus)

Dynamic CD138 surface expression regulates switch between myeloma growth and dissemination

Akhmetzyanova, I., McCarron, M. J., Parekh, S., Chesi, M., Bergsagel, P. L. & Fooksman, D. R., Jan 1 2019, (Accepted/In press) In : Leukemia.

Research output: Contribution to journalArticle

Growth
Syndecan-1
Bone and Bones
Plasma Cells
Cell Movement
2 Citations (Scopus)

Germline predisposition and copy number alteration in pre-stage lung adenocarcinomas presenting as ground-glass nodules

Ren, Y., Huang, S., Dai, C., Xie, D., Zheng, L., Xie, H., Zheng, H., She, Y., Zhou, F., Wang, Y., Li, P., Fei, K., Jiang, G., Zhang, Y., Su, B., Alejandro Sweet-Cordero, E., Tran, N., Yang, Y. D., Patel, J. N., Rolfo, C. & 7 others, Rocco, G., Cardona, A. F., Tuzi, A., Suter, M. B., Yang, P., Xu, W. & Chen, C., Jan 1 2019, In : Frontiers in Oncology. 9, MAR, 288.

Research output: Contribution to journalArticle

Open Access
Glass
Germ-Line Mutation
Mutation
Exome
Mutagens

Inhibition of phosphatidylinositol 3-kinase by PX-866 suppresses temozolomide-induced autophagy and promotes apoptosis in glioblastoma cells

Harder, B. G., Peng, S., Sereduk, C. P., Sodoma, A. M., Kitange, G. J., Loftus, J. C., Sarkaria, J. N. & Tran, N. L., Nov 14 2019, In : Molecular Medicine. 25, 1, 49.

Research output: Contribution to journalArticle

Open Access
temozolomide
Phosphatidylinositol 3-Kinase
Autophagy
Glioblastoma
Apoptosis
1 Citation (Scopus)

Integrated RNA-seq and ChIP-seq analysis reveals a feed-forward loop regulating H3K9ac and key labor drivers in human placenta

Wang, B., Wang, P., Parobchak, N., Treff, N., Tao, X., Wang, J. & Rosen, T., Jan 15 2019, In : Placenta. 76, p. 40-50 11 p.

Research output: Contribution to journalArticle

RNA Sequence Analysis
Placenta
Chromatin
Trophoblasts
Genes
2 Citations (Scopus)

Leveraging spatial variation in tumor purity for improved somatic variant calling of archival tumor only samples

Halperin, R. F., Liang, W. S., Kulkarni, S., Tassone, E. E., Adkins, J., Enriquez, D., Tran, N., Hank, N. C., Newell, J., Kodira, C., Korn, R., Berens, M. E., Kim, S. & Byron, S. A., Jan 1 2019, In : Frontiers in Oncology. 9, MAR

Research output: Contribution to journalArticle

Open Access
Neoplasms
Exome
Translational Medical Research
Glioblastoma
Genomics

MetaMarker: A pipeline for de novo discovery of novel metagenomic biomarkers

Koohi-Moghadam, M., Borad, M. J., Tran, N. L., Swanson, K. R., Boardman, L. A., Sun, H. & Wang, J., Oct 1 2019, In : Bioinformatics. 35, 19, p. 3812-3814 3 p.

Research output: Contribution to journalArticle

Metagenomics
Biomarkers
Colorectal Cancer
Pipelines
Metagenome

MYC dysregulation in the progression of multiple myeloma

MMRF CoMMpass Network, Jan 1 2019, (Accepted/In press) In : Leukemia.

Research output: Contribution to journalLetter

Multiple Myeloma

Next-Generation Sequencing in Human Genetic Studies: Genome Technologies and Applications to Human Genetic Studies

Wang, J., Wang, K., Liu, X., Sham, P. & Zhao, Z., Feb 1 2019, In : Human Heredity. 83, 3, p. 105-106 2 p.

Research output: Contribution to journalEditorial

Open Access
Medical Genetics
Genome
Technology
1 Citation (Scopus)

Oncolytic immunotherapy and bortezomib synergy improves survival of refractory multiple myeloma in a preclinical model

Thirukkumaran, C. M., Shi, Z. Q., Nuovo, G. J., Luider, J., Kopciuk, K. A., Dong, Y., Mostafa, A. A., Thakur, S., Gratton, K., Yang, A., Chin, A. C., Coffey, M. C., Jimenez-Zepeda, V. H., Stewart, D., Chesi, M., Bergsagel, P. L. & Morris, D., Mar 12 2019, In : Blood advances. 3, 5, p. 797-812 16 p.

Research output: Contribution to journalArticle

Open Access
Multiple Myeloma
Immunotherapy
Survival
Neoplasms
Therapeutics

Real-Time Visualization of an Acoustically Active Injection Catheter with Ultrasound Imaging: Algorithm and in Vivo Validation in a Swine Model

Kumar, V., Katayama, M., Peavler, R., Alizad, A., Belohlavek, M. & Fatemi, M., Jan 1 2019, In : IEEE Transactions on Biomedical Engineering. 66, 11, p. 3212-3219 8 p., 8656513.

Research output: Contribution to journalArticle

Catheters
Needles
Visualization
Ultrasonics
Imaging techniques
2018

Acoustic navigation of intramyocardial injection needle catheter using color doppler echocardiography

Katayama, M., Kumar, V., Zarbatany, D., Vaitkus, V., Fortuin, F. D., Fatemi, M. & Belohlavek, M., Jan 1 2018, In : IEEE International Ultrasonics Symposium, IUS. 2018-January, 8579717.

Research output: Contribution to journalConference article

echocardiography
navigation
needles
injection
color
3 Citations (Scopus)

An Interposed Pad in Open-Chest Echocardiographic Porcine Scans for Mimicking Ultrasound Signal Attenuation in a Human Chest

Kinnick, R. R., Katayama, M. & Belohlavek, M., Feb 1 2018, In : Journal of Ultrasound in Medicine. 37, 2, p. 501-509 9 p.

Research output: Contribution to journalArticle

Swine
Thorax
Urethane
Thoracic Wall
Transducers
4 Citations (Scopus)

A Novel Signaling Complex between TROY and EGFR Mediates Glioblastoma Cell Invasion

Ding, Z., Roos, A., Kloss, J., Dhruv, H., Peng, S., Pirrotte, P., Eschbacher, J. M., Tran, N. & Loftus, J. C., Feb 1 2018, In : Molecular Cancer Research. 16, 2, p. 322-332 11 p.

Research output: Contribution to journalArticle

Glioblastoma
temozolomide
Neoplasms
Epidermal Growth Factor
Survival
5 Citations (Scopus)

Antigen-mediated regulation in monoclonal gammopathies and myeloma

Nair, S., Sng, J., Boddupalli, C. S., Seckinger, A., Chesi, M., Fulciniti, M., Zhang, L., Rauniyar, N., Lopez, M., Neparidze, N., Parker, T., Munshi, N. C., Sexton, R., Barlogie, B., Orlowski, R., Bergsagel, P. L., Hose, D., Flavell, R. A., Mistry, P. K., Meffre, E. & 1 others, Dhodapkar, M. V., Apr 19 2018, In : JCI insight. 3, 8

Research output: Contribution to journalArticle

Open Access
Paraproteinemias
Antigens
Gaucher Disease
Plasma Cells
Multiple Myeloma
17 Citations (Scopus)

Assessment of the Clinical Relevance of BRCA2 Missense Variants by Functional and Computational Approaches

Guidugli, L., Shimelis, H., Masica, D. L., Pankratz, V. S., Lipton, G. B., Singh, N., Hu, C., Monteiro, A. N. A., Lindor, N. M., Goldgar, D. E., Karchin, R., Iversen, E. S. & Couch, F. J., Jan 1 2018, (Accepted/In press) In : American Journal of Human Genetics.

Research output: Contribution to journalArticle

Virulence
Homologous Recombination
Endophenotypes
Recombinational DNA Repair
DNA
2 Citations (Scopus)
genetic research
Genetic Research
Spouses
research results
spouse
12 Citations (Scopus)

Blocking IFNAR1 inhibits multiple myeloma-driven Treg expansion and immunosuppression

Kawano, Y., Zavidij, O., Park, J., Moschetta, M., Kokubun, K., Mouhieddine, T. H., Manier, S., Mishima, Y., Murakami, N., Bustoros, M., Pistofidis, R. S., Reidy, M., Shen, Y. J., Rahmat, M., Lukyanchykov, P., Karreci, E. S., Tsukamoto, S., Shi, J., Takagi, S., Huynh, D. & 7 others, Sacco, A., Tai, Y. T., Chesi, M., Bergsagel, P. L., Roccaro, A. M., Azzi, J. & Ghobrial, I. M., Jun 1 2018, In : Journal of Clinical Investigation. 128, 6, p. 2487-2499 13 p.

Research output: Contribution to journalArticle

Interferon Type I
Immunosuppressive Agents
Multiple Myeloma
Immunosuppression
Regulatory T-Lymphocytes
61 Citations (Scopus)

Canadian Association of Radiologists White Paper on Artificial Intelligence in Radiology

Canadian Association of Radiologists (CAR) Artificial Intelligence Working Group, Jan 1 2018, (Accepted/In press) In : Canadian Association of Radiologists Journal.

Research output: Contribution to journalArticle

Artificial Intelligence
Radiology
Learning
Patient Care
Workflow
4 Citations (Scopus)

Cohort Profile: The Colon Cancer Family Registry Cohort (CCFRC)

Colon Cancer Family Registry Cohort Investigators , Apr 1 2018, In : International Journal of Epidemiology. 47, 2

Research output: Contribution to journalArticle

Medical History Taking
Preschool Children
New Zealand
Colonic Neoplasms
Canada
4 Citations (Scopus)

Colonoscopy surveillance for high risk polyps does not always prevent colorectal cancer

Mouchli, M. A., Ouk, L., Scheitel, M. R., Chaudhry, A. P., Felmlee-Devine, D., Grill, D. E., Rashtak, S., Wang, P., Wang, J., Chaudhry, R., Smyrk, T. C., Oberg, A. L., Druliner, B. R. & Boardman, L. A., Feb 28 2018, In : World Journal of Gastroenterology. 24, 8, p. 905-916 12 p.

Research output: Contribution to journalArticle

Colonoscopy
Polyps
Adenoma
Colorectal Neoplasms
Risk Management
6 Citations (Scopus)

Comprehensive annotation of BRCA1 and BRCA2 missense variants by functionally validated sequence-based computational prediction models

Hart, S., Hoskin, T., Shimelis, H., Moore, R. M., Feng, B., Thomas, A., Lindor, N. M., Polley, E., Goldgar, D. E., Iversen, E., Monteiro, A. N. A., Suman, V. J. & Couch, F. J., Jun 8 2018, (Accepted/In press) In : Genetics in Medicine. p. 1-10 10 p.

Research output: Contribution to journalArticle

Politics
Computer Simulation
Area Under Curve
BRCA2 Protein
Confidence Intervals
4 Citations (Scopus)

Computed Tomography-Based Texture Analysis to Determine Human Papillomavirus Status of Oropharyngeal Squamous Cell Carcinoma

Ranjbar, S., Ning, S., Zwart, C. M., Wood, C. P., Weindling, S. M., Wu, T., Mitchell, J. R., Li, J. & Hoxworth, J. M., Mar 1 2018, In : Journal of Computer Assisted Tomography. 42, 2, p. 299-305 7 p.

Research output: Contribution to journalArticle

Squamous Cell Carcinoma
Tomography
Papillomavirus Infections
Neck
Machine Learning
11 Citations (Scopus)

Computer-aided diagnosis of contrast-enhanced spectral mammography: A feasibility study

Patel, B., Ranjbar, S., Wu, T., Pockaj, B. A., Li, J., Zhang, N., Lobbes, M., Zhang, B. & Mitchell, J. R., Jan 1 2018, In : European Journal of Radiology. 98, p. 207-213 7 p.

Research output: Contribution to journalArticle

Feasibility Studies
Mammography
Breast
Research Ethics Committees
Radiologists
1 Citation (Scopus)

Current Approaches to Cancer Genetic Counseling Services for Spanish-Speaking Patients

Augusto, B., Kasting, M. L., Couch, F. J., Lindor, N. M. & Vadaparampil, S. T., Jun 7 2018, (Accepted/In press) In : Journal of Immigrant and Minority Health. p. 1-4 4 p.

Research output: Contribution to journalArticle

Genetic Services
Genetic Counseling
Hispanic Americans
Neoplasms
Communication Barriers
2 Citations (Scopus)

Developing a Process for Returning Medically Actionable Genomic Variants to Latino Patients in a Federally Qualified Health Center

Shaibi, G. Q., Kullo, I. J., Singh, D. P., Sharp, R. R., De Filippis, E. A., Cuellar, I., Hernandez, V., Levey, S., Radecki Breitkopf, C., Olson, J. E., Cerhan, J. R., Mandarino, L. J., Thibodeau, S. N. & Lindor, N. M., Jan 1 2018, (Accepted/In press) In : Public Health Genomics.

Research output: Contribution to journalArticle

Hyperlipidemias
Hispanic Americans
Community Health Planning
Clinical Decision Support Systems
Community Health Centers
1 Citation (Scopus)

Differential expression of the TWEAK receptor Fn14 in IDH1 wild-type and mutant gliomas

Hersh, D. S., Peng, S., Dancy, J. G., Galisteo, R., Eschbacher, J. M., Castellani, R. J., Heath, J. E., Legesse, T., Kim, A. J., Woodworth, G. F., Tran, N. & Winkles, J. A., Feb 16 2018, (Accepted/In press) In : Journal of Neuro-Oncology. p. 1-10 10 p.

Research output: Contribution to journalArticle

Isocitrate Dehydrogenase
Glioma
Glioblastoma
decitabine
TWEAK receptor

Discovery of surface target proteins linking drugs, molecular markers, gene regulation, protein networks, and disease by using a web-based platform targets-search

Yan, B., Wang, P., Wang, J. & Boheler, K. R., Jan 1 2018, Methods in Molecular Biology. Humana Press Inc., Vol. 1722. p. 331-344 14 p. (Methods in Molecular Biology; vol. 1722).

Research output: Chapter in Book/Report/Conference proceedingChapter

Membrane Proteins
Ewing's Sarcoma
Pharmaceutical Preparations
Proteins
Drug Repositioning
6 Citations (Scopus)

DNA mismatch repair protein deficient non-neoplastic colonic crypts: a novel indicator of Lynch syndrome

Pai, R., Dudley, B., Karloski, E., Brand, R. E., O’Callaghan, N., Rosty, C., Buchanan, D. D., Jenkins, M. A., Thibodeau, S. N., French, A. J., Lindor, N. M. & Pai, R. K., Jun 8 2018, (Accepted/In press) In : Modern Pathology. p. 1-11 11 p.

Research output: Contribution to journalArticle

Hereditary Nonpolyposis Colorectal Neoplasms
DNA Mismatch Repair
Colorectal Neoplasms
Proteins
Protein Deficiency
15 Citations (Scopus)

Dysregulated IL-18 Is a Key Driver of Immunosuppression and a Possible Therapeutic Target in the Multiple Myeloma Microenvironment

Nakamura, K., Kassem, S., Cleynen, A., Chrétien, M. L., Guillerey, C., Putz, E. M., Bald, T., Förster, I., Vuckovic, S., Hill, G. R., Masters, S. L., Chesi, M., Bergsagel, P. L., Avet-Loiseau, H., Martinet, L. & Smyth, M. J., Jan 1 2018, (Accepted/In press) In : Cancer Cell.

Research output: Contribution to journalArticle

Interleukin-18
Multiple Myeloma
Immunosuppression
Therapeutics
T-Lymphocytes
5 Citations (Scopus)

EGFRvIII–Stat5 signaling enhances glioblastoma cell migration and survival

Roos, A., Dhruv, H. D., Peng, S., Inge, L. J., Tuncali, S., Pineda, M., Millard, N., Mayo, Z., Eschbacher, J. M., Loftus, J. C., Winkles, J. A. & Tran, N., Jul 1 2018, In : Molecular Cancer Research. 16, 7, p. 1185-1195 11 p.

Research output: Contribution to journalArticle

Glioblastoma
Cell Movement
Cell Survival
Neoplasms
Pimozide
1 Citation (Scopus)

Erratum: Author Correction: UClncR: Ultrafast and comprehensive long non-coding RNA detection from RNA-seq (Scientific reports (2017) 7 1 (14196))

Sun, Z., Nair, A., Chen, X., Prodduturi, N., Wang, J. & Kocher, J. P., Mar 20 2018, In : Scientific reports. 8, 1, 1 p.

Research output: Contribution to journalComment/debate

Open Access
Long Noncoding RNA
RNA
26 Citations (Scopus)

Evaluation of pre-analytical factors affecting plasma DNA analysis

Markus, H., Contente-Cuomo, T., Farooq, M., Liang, W. S., Borad, M. J., Sivakumar, S., Gollins, S., Tran, N., Dhruv, H. D., Berens, M. E., Bryce, A. H., Sekulic, A. D., Ribas, A., Trent, J. M., Lorusso, P. M. & Murtaza, M., Dec 1 2018, In : Scientific Reports. 8, 1, 7375.

Research output: Contribution to journalArticle

DNA
cells
sampling
droplets
blood
11 Citations (Scopus)

Evaluation of tools for highly variable gene discovery from single-cell RNA-seq data

Yip, S. H., Sham, P. C. & Wang, J., Mar 27 2018, In : Briefings in bioinformatics. 20, 4, p. 1583-1589 7 p.

Research output: Contribution to journalArticle

Open Access
RNA Sequence Analysis
Genetic Association Studies
RNA
Genes
Gene expression

Genetic susceptibility markers for a breast-colorectal cancer phenotype: Exploratory results from genome-wide association studies

Pande, M., Joon, A., Brewster, A. M., Chen, W. V., Hopper, J. L., Eng, C., Shete, S., Casey, G., Schumacher, F., Lin, Y., Harrison, T. A., White, E., Ahsan, H., Andrulis, I. L., Whittemore, A. S., John, E. M., Win, A. K., Makalic, E., Schmidt, D. F., Kapuscinski, M. K. & 8 others, Ochs-Balcom, H. M., Gallinger, S., Jenkins, M. A., Newcomb, P. A., Lindor, N. M., Peters, U., Amos, C. I. & Lynch, P. M., Apr 1 2018, In : PLoS One. 13, 4, e0196245.

Research output: Contribution to journalArticle

Genome-Wide Association Study
Genetic Predisposition to Disease
colorectal neoplasms
Genetic Markers
breast neoplasms
6 Citations (Scopus)

Genomic characterization of upper-tract urothelial carcinoma in patients with Lynch syndrome

Donahue, T. F., Bagrodia, A., Audenet, F., Donoghue, M. T. A., Cha, E. K., Sfakianos, J. P., Sperling, D., Al-Ahmadie, H., Clendenning, M., Rosty, C., Buchanan, D. D., Jenkins, M., Hopper, J., Winship, I., Templeton, A. S., Walsh, M. F., Stadler, Z. K., Iyer, G., Taylor, B., Coleman, J. & 3 others, Lindor, N. M., Solit, D. B. & Bochner, B. H., Jan 1 2018, In : JCO Precision Oncology. 2

Research output: Contribution to journalArticle

Open Access
Hereditary Nonpolyposis Colorectal Neoplasms
Carcinoma
Mutation
Neoplasms
Germ-Line Mutation
5 Citations (Scopus)

GWAS4D: Multidimensional analysis of context-specific regulatory variant for human complex diseases and traits

Huang, D., Yi, X., Zhang, S., Zheng, Z., Wang, P., Xuan, C., Sham, P. C., Wang, J. & Li, M. J., Jul 2 2018, In : Nucleic Acids Research. 46, W1, p. W114-W120

Research output: Contribution to journalArticle

Genome-Wide Association Study
Genomics
Epigenomics
Single Nucleotide Polymorphism
Coronary Artery Disease
15 Citations (Scopus)

Hybrid-denovo: A de novo OTU-picking pipeline integrating single-end and paired-end 16S sequence tags

Chen, X., Johnson, S., Jeraldo, P., Wang, J., Chia, N., Kocher, J. P. A. & Chen, J., Mar 1 2018, In : GigaScience. 7, 3, p. 1-7 7 p.

Research output: Contribution to journalComment/debate

Pipelines
Genes
Quality control
rRNA Genes
Rheumatoid Arthritis
1 Citation (Scopus)

Importin-β and exportin-5 are strong biomarkers of productive reoviral infection of cancer cells

Nuovo, G., Tran, H., Gutierrez, A., Fadda, P., Pichiorri, F., Caserta, E., Hofmeister, C. C., Chesi, M., Bergsagel, P. L., Morris, D., Shi, Q., Coffey, M. & Thirukkumaran, C., Feb 1 2018, In : Annals of Diagnostic Pathology. 32, p. 28-34 7 p.

Research output: Contribution to journalArticle

Karyopherins
Biomarkers
Capsid Proteins
Infection
Caspase 3

Inferring RNA sequence preferences for poorly studied RNA-binding proteins based on co-evolution

Yang, S., Wang, J. & Ng, R. T., Mar 12 2018, In : BMC Bioinformatics. 19, 1, 96.

Research output: Contribution to journalArticle

RNA-Binding Proteins
Coevolution
RNA
Protein
Computational methods
3 Citations (Scopus)

Inhibitors of the protein disulfide isomerase family for the treatment of multiple myeloma

Robinson, R. M., Reyes, L., Duncan, R. M., Bian, H., Reitz, A. B., Manevich, Y., McClure, J. J., Champion, M. M., Chou, C. J., Sharik, M. E., Chesi, M., Bergsagel, P. L. & Dolloff, N. G., Jan 1 2018, (Accepted/In press) In : Leukemia.

Research output: Contribution to journalArticle

Protein Disulfide-Isomerases
Multiple Myeloma
Proteasome Inhibitors
Click Chemistry
Small Molecule Libraries
10 Citations (Scopus)

Integrated mapping of pharmacokinetics and pharmacodynamics in a patient-derived xenograft model of glioblastoma

Randall, E. C., Emdal, K. B., Laramy, J. K., Kim, M., Roos, A., Calligaris, D., Regan, M. S., Gupta, S. K., Mladek, A. C., Carlson, B. L., Johnson, A. J., Lu, F. K., Xie, X. S., Joughin, B. A., Reddy, R. J., Peng, S., Abdelmoula, W. M., Jackson, P. R., Kolluri, A., Kellersberger, K. A. & 8 others, Agar, J. N., Lauffenburger, D. A., Swanson, K., Tran, N., Elmquist, W. F., White, F. M., Sarkaria, J. N. & Agar, N. Y. R., Dec 1 2018, In : Nature Communications. 9, 1, 4904.

Research output: Contribution to journalArticle

Pharmacodynamics
Pharmacokinetics
Glioblastoma
Heterografts
drugs
6 Citations (Scopus)

Integrated transcriptomic and regulatory network analyses identify microRNA-200c as a novel repressor of human pluripotent stem cell-derived cardiomyocyte differentiation and maturation

Poon, E. N. Y., Hao, B., Guan, D., Jun Li, M., Lu, J., Yang, Y., Wu, B., Wu, S. C. M., Webb, S. E., Liang, Y., Miller, A. L., Yao, X., Wang, J., Yan, B. & Boheler, K. R., May 1 2018, In : Cardiovascular Research. 114, 6, p. 894-906 13 p.

Research output: Contribution to journalArticle

Pluripotent Stem Cells
MicroRNAs
Cardiac Myocytes
Transcription Factors
Gene Regulatory Networks
2 Citations (Scopus)

Interaction between polymorphisms in aspirin metabolic pathways, regular aspirin use and colorectal cancer risk: A case-control study in unselected white European populations

Sheth, H., Northwood, E., Ulrich, C. M., Scherer, D., Elliott, F., Barrett, J. H., Forman, D., Roland Wolf, C., Smith, G., Jackson, M. S., Santibanez-Koref, M., Haile, R., Casey, G., Jenkins, M., Win, A. K., Hopper, J. L., Le Marchand, L., Lindor, N. M., Thibodeau, S. N., Potter, J. D. & 2 others, Burn, J. & Timothy Bishop, D., Feb 1 2018, In : PLoS One. 13, 2, e0192223.

Research output: Contribution to journalArticle

aspirin
Metabolic Networks and Pathways
case-control studies
Polymorphism
colorectal neoplasms
11 Citations (Scopus)

Metallochaperone UreG serves as a new target for design of urease inhibitor: A novel strategy for development of antimicrobials

Yang, X., Koohi-Moghadam, M., Wang, R., Chang, Y. Y., Woo, P. C. Y., Wang, J., Li, H. & Sun, H., Jan 1 2018, In : PLoS Biology. 16, 1, e2003887.

Research output: Contribution to journalArticle

Metallochaperones
urease inhibitors
Urease
urease
anti-infective agents
13 Citations (Scopus)

Microbiota-driven interleukin-17-producing cells and eosinophils synergize to accelerate multiple myeloma progression

Calcinotto, A., Brevi, A., Chesi, M., Ferrarese, R., Garcia Perez, L., Grioni, M., Kumar, S. K., Garbitt, V. M., Sharik, M. E., Henderson, K. J., Tonon, G., Tomura, M., Miwa, Y., Esplugues, E., Flavell, R. A., Huber, S., Canducci, F., Rajkumar, S. V., Bergsagel, P. L. & Bellone, M., Dec 1 2018, In : Nature Communications. 9, 1, 4832.

Research output: Contribution to journalArticle

eosinophils
interleukins
Interleukin-17
Microbiota
Multiple Myeloma