Jacksonville, FL

Research Output 1976 2019

1998
16 Citations (Scopus)

Phase I trial of edatrexate plus carboplatin in advanced solid tumors: Amelioration of dose-limiting mucositis by ice chip cryotherapy

Edelman, M. J., Gandara, D. R., Perez, E. A., Lau, D., Lauder, I., Turrell, C., Uhrich, M. & Meyers, F., 1998, In : Investigational New Drugs. 16, 1, p. 69-75 7 p.

Research output: Contribution to journalArticle

Mucositis
Cryotherapy
Carboplatin
Ice
Neoplasms
168 Citations (Scopus)

Phenotypic variability of Gerstmann-Straussler-Scheinker disease is associated with prion protein heterogeneity

Piccardo, P., Dlouhy, S. R., Lievens, P. M. J., Young, K., Bird, T. D., Nochlin, D., Dickson, D. W., Vinters, H. V., Zimmerman, T. R., Mackenzie, I. R. A., Kish, S. J., Ang, L. C., De Carli, C., Pocchiari, M., Brown, P., Gibbs, C. J., Gajdusek, D. C., Bugiani, O., Ironside, J., Tagliavini, F. & 1 others, Ghetti, B., Oct 1998, In : Journal of Neuropathology and Experimental Neurology. 57, 10, p. 979-988 10 p.

Research output: Contribution to journalArticle

Gerstmann-Straussler-Scheinker Disease
Protein Isoforms
Prion Proteins
Endopeptidase K
Creutzfeldt-Jakob Syndrome
148 Citations (Scopus)

Pick's disease: A modern approach

Dickson, D. W., 1998, In : Brain Pathology. 8, 2, p. 339-354 16 p.

Research output: Contribution to journalArticle

Pick Disease of the Brain
tau Proteins
Neuroglia
Hippocampus
Alzheimer Disease
243 Citations (Scopus)

Pilot evaluation of venlafaxine hydrochloride for the therapy of hot flashes in cancer survivors

Loprinzi, C. L., Pisansky, T. M., Fonseca, R., Sloan, J. A., Zahasky, K. M., Quella, S. K., Novotny, P. J., Rummans, T. A., Dumesic, D. A. & Perez, E. A., Jul 1998, In : Journal of Clinical Oncology. 16, 7, p. 2377-2381 5 p.

Research output: Contribution to journalArticle

Hot Flashes
Survivors
Neoplasms
Therapeutics
Phase II Clinical Trials
41 Citations (Scopus)

Polymerase chain reaction-based microsatellite polymorphism analysis of follicular and Hurthle cell neoplasms of the thyroid

Segev, D. L., Saji, M., Phillips, G. S., Westra, W. H., Takiyama, Y., Piantadosi, S., Smallridge, R. C., Nishiyama, R. H., Udelsman, R. & Zeiger, M. A., 1998, In : Journal of Clinical Endocrinology and Metabolism. 83, 6, p. 2036-2042 7 p.

Research output: Contribution to journalArticle

Oxyphil Cells
Polymerase chain reaction
Polymorphism
Thyroid Neoplasms
Microsatellite Repeats
6 Citations (Scopus)

Post-stroke complications: Epidemiology and prospects for pharmacological intervention during rehabilitation

Meschia, J. F. & Bruno, A., 1998, In : CNS Drugs. 9, 5, p. 357-370 14 p.

Research output: Contribution to journalArticle

Epidemiology
Rehabilitation
Stroke
Pharmacology
Nortriptyline
28 Citations (Scopus)

Prospects for a prophylactic HPV vaccine: Rationale and future implications for cervical cancer screening

Sherman, M. E., Schiffman, M. H., Strickler, H. & Hildesheim, A., 1998, In : Diagnostic Cytopathology. 18, 1, p. 5-9 5 p.

Research output: Contribution to journalArticle

Papillomavirus Vaccines
Early Detection of Cancer
Uterine Cervical Neoplasms
Health Services Accessibility
Papillomavirus Infections
14 Citations (Scopus)

Purkinje cells in olivopontocerebellar atrophy and granule cell-type cerebellar degeneration: An immunohistochemical study

Kato, S., Hayashi, H., Mikoshiba, K., Hirano, A., Yen, S. H. & Ohama, E., Jul 1998, In : Acta Neuropathologica. 96, 1, p. 67-74 8 p.

Research output: Contribution to journalArticle

Olivopontocerebellar Atrophies
Purkinje Cells
Dendritic Spines
Neurofilament Proteins
Synaptophysin
9 Citations (Scopus)

Radiographic assessment of hyperinflation: Correlation with objective chest radiographic measurements and mechanical ventilator parameters

Johnson, M., Ely, E. W., Chiles, C., Bowton, D. L., Friemanas, R. I., Choplin, R. H. & Haponik, E. F., Jan 1 1998, In : Chest. 113, 6, p. 1698-1704 7 p.

Research output: Contribution to journalArticle

Barotrauma
Mechanical Ventilators
Thorax
Positive-Pressure Respiration
Incidence
51 Citations (Scopus)

Receptors for advanced glycosylation endproducts in human brain: Role in brain homeostasis

Li, J. J., Dickson, D. W., Hof, P. R. & Vlassara, H., 1998, In : Molecular Medicine. 4, 1, p. 46-60 15 p.

Research output: Contribution to journalArticle

Glycosylation
Homeostasis
Carrier Proteins
Brain
Neuroglia
331 Citations (Scopus)

REM sleep behavior disorder and degenerative dementia: An association likely reflecting Lewy body disease

Boeve, B. F., Silber, M. H., Ferman, T. J., Kokmen, E., Smith, G. E., Ivnik, R. J., Parisi, J. E., Olson, E. J. & Petersen, R. C., Aug 1998, In : Neurology. 51, 2, p. 363-370 8 p.

Research output: Contribution to journalArticle

REM Sleep Behavior Disorder
Lewy Body Disease
Dementia
Parkinsonian Disorders
Lewy Bodies
62 Citations (Scopus)

Reversible segmental cerebral arterial vasospasm and cerebral infarction: Possible association with excessive use of sumatriptan and Midrin

Meschia, J. F., Malkoff, M. D. & Biller, J., May 1998, In : Archives of Neurology. 55, 5, p. 712-714 3 p.

Research output: Contribution to journalArticle

Sumatriptan
Intracranial Vasospasm
Cerebral Infarction
Tablets
Nicardipine
26 Citations (Scopus)

Sequence-dependent cytotoxicity of etoposide and paclitaxel in human breast and lung cancer cell lines

Perez, E. A. & Buckwalter, C. A., 1998, In : Cancer Chemotherapy and Pharmacology. 41, 6, p. 448-452 5 p.

Research output: Contribution to journalArticle

Etoposide
Cytotoxicity
Paclitaxel
Lung Neoplasms
Cells
57 Citations (Scopus)

Sequential intrahepatic fluorodeoxyuridine and systemic fluorouracil plus leucovorin for the treatment of metastatic colorectal cancer confined to the liver

O'Connell, M. J., Nagorney, D. M., Bernath, A. M., Schroeder, G., Fitzgibbons, R. J., Mailliard, J. A., Burch, P., Bolton, J. S., Colon-Otero, G. & Krook, J. E., Jul 1998, In : Journal of Clinical Oncology. 16, 7, p. 2528-2533 6 p.

Research output: Contribution to journalArticle

Floxuridine
Leucovorin
Fluorouracil
Colorectal Neoplasms
Neoplasm Metastasis
62 Citations (Scopus)

Ser-262 in human recombinant tau protein is a markedly more favorable site for phosphorylation by CaMKII than PKA or PhK

Sironi, J. J., Yen, S. H., Gondal, J. A., Wu, Q., Grundke-Iqbal, I. & Iqbal, K., Oct 9 1998, In : FEBS Letters. 436, 3, p. 471-475 5 p.

Research output: Contribution to journalArticle

Calcium-Calmodulin-Dependent Protein Kinase Type 2
tau Proteins
Recombinant proteins
Phosphorylation
Recombinant Proteins
3 Citations (Scopus)

Serotonin: And what about its side effects?

Richelson, E., 1998, In : Depression and Anxiety. 7, SUPPL. 1, p. 18-20 3 p.

Research output: Contribution to journalArticle

Drug Interactions
Antidepressive Agents
Serotonin
Neurotransmitter Receptor
Drug-Related Side Effects and Adverse Reactions
81 Citations (Scopus)

Specific gene blockade shows that peptide nucleic acids readily enter neuronal cells in vivo

Tyler, B. M., Mc Cormick, D. J., Hoshall, C. V., Douglas, C. L., Jansen, K., Lacy, B. W., Cusack, B. & Richelson, E., Jan 16 1998, In : FEBS Letters. 421, 3, p. 280-284 5 p.

Research output: Contribution to journalArticle

Peptide Nucleic Acids
Neurotensin
Genes
Hypothermia
Periaqueductal Gray
6 Citations (Scopus)

Spinal cord localization in the treatment of lung cancer: Use of radiographic landmarks

Miller, R. C., Bonner, J. A., Wenger, D. E., Foote, R. L., Kisrow, K. L. & Shaw, E. G., Jan 15 1998, In : International Journal of Radiation Oncology Biology Physics. 40, 2, p. 347-351 5 p.

Research output: Contribution to journalArticle

spinal cord
landmarks
lungs
Lung Neoplasms
Spinal Cord
3 Citations (Scopus)

Surgically responsive focal tremor associated with a frontal convexity meningioma

Evidente, V. G. H., Gwinn, K. A., Caviness, J. N., Hirschorn, K. & Deen, H. G., Aug 1998, In : European Neurology. 40, 2, p. 107-108 2 p.

Research output: Contribution to journalArticle

Meningeal Neoplasms
Frontal Lobe
Meningioma
Tremor
Magnetic Resonance Imaging
29 Citations (Scopus)

Synergistic therapy of breast cancer with Y90-chimeric L6 and paclitaxel in the xenografted mouse model: Development of a clinical protocol

DeNardo, S. J., Richman, C. M., Kukis, D. L., Shen, S., Lamborn, K. R., Miers, L. A., Kroger, L. A., Perez, E. A. & Denardo, G. L., 1998, In : Anticancer Research. 18, 6 A, p. 4011-4018 8 p.

Research output: Contribution to journalArticle

Radioimmunotherapy
Clinical Protocols
Paclitaxel
Breast Neoplasms
Therapeutics
26 Citations (Scopus)

Synthesis of (2S)-2-amino-3-(1H-4-indolyl)propanoic acid, a novel tryptophan analog for structural modification of bioactive peptides

Fauq, A. H., Hong, F., Cusack, B., Tyler, B. M., Pang, Y-P. & Richelson, E., Dec 11 1998, In : Tetrahedron Asymmetry. 9, 23, p. 4127-4134 8 p.

Research output: Contribution to journalArticle

Aromatic Amino Acids
Solid-Phase Synthesis Techniques
tryptophan
activity (biology)
Tryptophan
50 Citations (Scopus)

Synthesis of a potent wide-spectrum serotonin-, norepinephrine-, dopamine-reuptake inhibitor (SNDRI) and a species-selective dopamine-reuptake inhibitor based on the gamma-amino alcohol functional group

Carlier, P. R., Lo, M. M. C., Lo, P. C. K., Richelson, E., Tatsumi, M., Reynolds, I. J. & Sharma, T. A., Mar 3 1998, In : Bioorganic and Medicinal Chemistry Letters. 8, 5, p. 487-492 6 p.

Research output: Contribution to journalArticle

Dopamine Uptake Inhibitors
Amino Alcohols
N-Methylaspartate
Functional groups
Antidepressive Agents
5 Citations (Scopus)

The effect of flufenamic acid on gastrointestinal myoelectrical activity and transit time in dogs

Farrugia, G., Nitecki, S., Harty, G. J., Camilleri, M. & Szurszewski, J. H., 1998, In : Gut. 42, 2, p. 258-265 8 p.

Research output: Contribution to journalArticle

Flufenamic Acid
Dogs
Small Intestine
Gastrointestinal Transit
Motor Activity
214 Citations (Scopus)

The role of Aβ42 in Alzheimer's disease

Younkin, S. G., Jun 1998, In : Journal of Physiology Paris. 92, 3-4, p. 289-292 4 p.

Research output: Contribution to journalArticle

Alzheimer Disease
Mutation
Foster Home Care
Amyloid Plaques
Cholinergic Agents
8 Citations (Scopus)

Tremor: How to determine if the patient has Parkinson's disease

Uitti, R. J., May 1998, In : Geriatrics. 53, 5, p. 30-36 7 p.

Research output: Contribution to journalArticle

Tremor
Parkinson Disease
Essential Tremor
Neurologic Manifestations
Primary Dysautonomias
13 Citations (Scopus)

Truncated presenilin 2 derived from differentially spliced mRNAs does not affect the ratio of amyloid β-peptide 1-42/1-40

Grünberg, J., Walter, J., Eckman, C., Capell, A., Schindzielorz, A., Younkin, S. G., Mehta, N., Hardy, J. & Haass, C., Oct 5 1998, In : NeuroReport. 9, 14, p. 3293-3299 7 p.

Research output: Contribution to journalArticle

Presenilin-2
Amyloid
Messenger RNA
Peptides
Presenilins
74 Citations (Scopus)

Twofold overexpression of human β-amyloid precursor proteins in transgenic mice does not affect the neuromotor, cognitive, or neurodegenerative sequelae following experimental brain injury

Murai, H., Pierce, J. E. S., Raghupathi, R., Smith, D. H., Saatman, K. E., Trojanowski, J. Q., Lee, V. M. Y., Loring, J. F., Eckman, C., Younkin, S. G. & Mcintosh, T. K., Mar 23 1998, In : Journal of Comparative Neurology. 392, 4, p. 428-438 11 p.

Research output: Contribution to journalArticle

Amyloid beta-Protein Precursor
Brain Injuries
Transgenic Mice
Yeast Artificial Chromosomes
Alzheimer Disease
17 Citations (Scopus)

Use of dexamethasone with 5-HT3-receptor antagonists for chemotherapy- induced nausea and vomiting

Perez, E. A., 1998, In : Cancer Journal from Scientific American. 4, 2, p. 72-77 6 p.

Research output: Contribution to journalArticle

Serotonin 5-HT3 Receptor Antagonists
Receptors, Serotonin, 5-HT3
Nausea
Dexamethasone
Vomiting
52 Citations (Scopus)

Use of the exercise treadmill to measure baseline functional status and surgical outcome in patients with severe lumbar spinal stenosis

Deen, H. G., Zimmerman, R. S., Lyons, M. K., McPhee, M. C., Verheijde, J. L. & Lemens, S. M., Jan 15 1998, In : Spine. 23, 2, p. 244-248 5 p.

Research output: Contribution to journalArticle

Spinal Stenosis
Exercise
Walking
Laminectomy
Exercise Tolerance

Valvular heart disease, pulmonary hypertension, and fenfluramine/phentermine use

Bruce, C. J. & Connolly, H. M., 1998, In : Cardiology Review. 15, 11, p. 17-19 3 p.

Research output: Contribution to journalArticle

Phentermine
United States Dept. of Health and Human Services
Fenfluramine
Heart Valve Diseases
Pulmonary Hypertension
9 Citations (Scopus)

Why, How, and When the cytological diagnosis of ASCUS should be eliminated

Schiffman, M., Solomon, D., Liaw, K. L. & Sherman, M. E., 1998, In : Journal of Lower Genital Tract Disease. 2, 3, p. 165-169 5 p.

Research output: Contribution to journalEditorial

Atypical Squamous Cells of the Cervix
1997
2 Citations (Scopus)
Vinblastine
Granulocyte Colony-Stimulating Factor
Non-Small Cell Lung Carcinoma
Antineoplastic Agents
Cisplatin
97 Citations (Scopus)

Altered metabolism of familial Alzheimer's disease linked amyloid precursor protein variants in yeast artificial chromosome transgenic mice

Lamb, B. T., Call, L. M., Slunt, H. H., Bardel, K. A., Lawler, A. M., Eckman, C. B., Younkin, S. G., Holtz, G., Wagner, S. L., Price, D. L., Sisodia, S. S. & Gearhart, J. D., Sep 1997, In : Human Molecular Genetics. 6, 9, p. 1535-1541 7 p.

Research output: Contribution to journalArticle

Yeast Artificial Chromosomes
Amyloid beta-Protein Precursor
Transgenic Mice
Alzheimer Disease
Genes
3 Citations (Scopus)

Altered thyroid axis function in Lewis rats with genetically defective hypothalamic CRH/VP neurosecretory cells

Whitnall, M. H. & Smallridge, R. C., 1997, In : Endocrine Research. 23, 4, p. 365-376 12 p.

Research output: Contribution to journalArticle

Pituitary Hormone-Releasing Hormones
Corticotropin-Releasing Hormone
Vasopressins
Thyroid Gland
Sprague Dawley Rats

Amntadin-Therapie - Ein unabhangiger Pradiktor einer verbesserten Uberlebensrate bei Morbus Parkinson

Translated title of the contribution: Amantadine treatment is an independent predictor of improved survival in Parkinson's diseaseUitti, R. J., Rajput, A. H., Ahlskog, J. E., Offord, K. P., Schroeder, D. R., Ho, M. M., Prasad, M., Rajput, A. & Basran, P., Sep 1997, In : Nervenheilkunde. 16, 7, p. 417-423 7 p.

Research output: Contribution to journalArticle

Amantadine
Parkinson Disease
Survival
Parkinsonian Disorders
Neuroprotective Agents
34 Citations (Scopus)

Anaphylactic reaction after cisatracurium

Clendenen, S. R., Harper, J. V., Wharen, R. E. & Guarderas, J. C., 1997, In : Anesthesiology. 87, 3, p. 690-692 3 p.

Research output: Contribution to journalArticle

Atracurium
Neuromuscular Blocking Agents
Anaphylaxis
cisatracurium
154 Citations (Scopus)

A new pathogenic mutation in the APP gene (1716V) increases the relative proportion of Aβ42(43)

Eckman, C. B., Mehta, N. D., Crook, R., Perez-tur, J., Prihar, G., Pfeiffer, E., Graff Radford, N. R., Hinder, P., Yager, D., Zenk, B., Refolo, L. M., Prada, C. M., Younkin, S. G., Hutton, M. & Hardy, J., Nov 1997, In : Human Molecular Genetics. 6, 12, p. 2087-2089 3 p.

Research output: Contribution to journalArticle

Mutation
Genes
Amyloid beta-Protein Precursor
Age of Onset
Alzheimer Disease
87 Citations (Scopus)

Apoptosis is inhibited early in the dysplasia-carcinoma sequence of Barrett esophagus

Katada, N., Hinder, R. A., Smyrk, T. C., Hirabayashi, N., Perdikis, G., Lund, R. J., Woodward, T. & Klingler, P. J., 1997, In : Archives of Surgery. 132, 7, p. 728-733 6 p.

Research output: Contribution to journalArticle

Barrett Esophagus
Adenocarcinoma
Apoptosis
Carcinoma
Esophagitis
75 Citations (Scopus)

Are patients with cirrhotic stage primary sclerosing cholangitis at risk for the development of hepatocellular cancer?

Harnois, D., Gores, G. J., Ludwig, J., Steers, J. L., La Russo, N. F. & Wiesner, R. H., Sep 1997, In : Journal of Hepatology. 27, 3, p. 512-516 5 p.

Research output: Contribution to journalArticle

Sclerosing Cholangitis
Liver Neoplasms
Hepatocellular Carcinoma
Liver Transplantation
Cholangiocarcinoma
104 Citations (Scopus)

Bcl-2 is overexpressed and alters the threshold for apoptosis in a cholangiocarcinoma cell line

Harnois, D., Que, F., Celli, A., La Russo, N. F. & Gores, G. J., Oct 1997, In : Hepatology. 26, 4, p. 884-890 7 p.

Research output: Contribution to journalArticle

B-Cell Leukemia
Cholangiocarcinoma
B-Cell Lymphoma
Apoptosis
Cell Line
135 Citations (Scopus)

Ceramide induces hepatocyte cell death through disruption of mitochondrial function in the rat

Arora, A. S., Jones, B. J., Patel, T. C., Bronk, S. F. & Gores, G. J., 1997, In : Hepatology. 25, 4, p. 958-963 6 p.

Research output: Contribution to journalArticle

Ceramides
Hepatocytes
Cell Death
Mitochondrial Membranes
Permeability
103 Citations (Scopus)

Cervical specimens collected in liquid buffer are suitable for both cytologic screening and ancillary human papillomavirus testing

Sherman, M. E., Schiffman, M. H., Lorincz, A. T., Herrero, R., Hutchinson, M. L., Bratti, C., Zahniser, D., Morales, J., Hildesheim, A., Helgesen, K., Kelly, D., Alfaro, M., Mena, F., Balmaceda, I., Mango, L. & Greenberg, M., Apr 25 1997, In : Cancer. 81, 2, p. 89-97 9 p.

Research output: Contribution to journalArticle

Buffers
Carcinoma
Colposcopy
Referral and Consultation
DNA
32 Citations (Scopus)

Characterization of the genomic structure, promoter region, and a tetranucleotide repeat polymorphism of the human neurotensin receptor gene

Le, F., Groshan, K., Zeng, X. P. & Richelson, E., 1997, In : Journal of Biological Chemistry. 272, 2, p. 1315-1322 8 p.

Research output: Contribution to journalArticle

Neurotensin Receptors
Polymorphism
Genetic Promoter Regions
Microsatellite Repeats
Genes
1 Citation (Scopus)

Chronic pancreatitis

Raimondo, M. & DiMagno, E. P., 1997, In : Current Opinion in Gastroenterology. 13, 5, p. 386-391 6 p.

Research output: Contribution to journalArticle

Chronic Pancreatitis
Genetic Markers
Pancreatitis
Abdominal Pain
Pancreas
84 Citations (Scopus)

Comparison of the hybrid capture tube test and PCR for detection of human papillomavirus DNA in cervical specimens

Cope, J. U., Hildesheim, A., Schiffman, M. H., Manos, M. M., Lörincz, A. T., Burk, R. D., Glass, A. G., Greer, C., Buckland, J., Helgesen, K., Scott, D. R., Sherman, M. E., Kurman, R. J. & Liaw, K. L., Sep 1997, In : Journal of Clinical Microbiology. 35, 9, p. 2262-2265 4 p.

Research output: Contribution to journalArticle

Polymerase Chain Reaction
DNA
Uterine Cervical Neoplasms
Cell Biology
Papanicolaou Test
14 Citations (Scopus)

Design, synthesis and pharmacological evaluation of active pyrrole based, nonpeptidic analogues of neurotensin(8-13)

Hong, F., Zaidi, J., Pang, Y-P., Cusack, B. & Richelson, E., Oct 21 1997, In : Journal of the Chemical Society - Perkin Transactions 1. 20, p. 2997-3003 7 p.

Research output: Contribution to journalArticle

neurotensin (8-13)
Pyrroles
Neurotensin Receptors
Neurotensin
Neuropeptides
6 Citations (Scopus)

Design, synthesis and pharmacological test of a quinoline based, nonpeptidic analogue of neurotensin(8-13)

Hong, F., Pang, Y-P., Cusack, B. & Richelson, E., Jul 21 1997, In : Journal of the Chemical Society - Perkin Transactions 1. 14, p. 2083-2088 6 p.

Research output: Contribution to journalArticle

neurotensin (8-13)
Neurotensin Receptors
Alkylation
Neuropeptides
Testing
48 Citations (Scopus)

Detection of albumin messenger RNA in hepatic and extrahepatic neoplasms: A marker of hepatocellular differentiation

Krishna, M., Lloyd, R. V. & Batts, K. P., 1997, In : American Journal of Surgical Pathology. 21, 2, p. 147-152 6 p.

Research output: Contribution to journalArticle

Differentiation Antigens
Liver Neoplasms
Albumins
Messenger RNA
Liver Cell Adenoma
148 Citations (Scopus)
Pathology
Amyloid Plaques
Neurofibrillary Tangles
Alzheimer Disease
Fats
16 Citations (Scopus)

Distal upper extremity function following proximal humeral resection and reconstruction for tumors: Contralateral comparison

Damron, T. A., Rock, M. G., O'Connor, M. I., Johnson, M. E., An, K. N., Pritchard, D. J., Sim, F. H. & Shives, T. C., Apr 1997, In : Annals of Surgical Oncology. 4, 3, p. 237-246 10 p.

Research output: Contribution to journalArticle

Forearm
Upper Extremity
Elbow
Pronation
Hand Strength