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Timothy J Nelson, MD, PhD

  • 3070 Citations
  • 29 Scopus h-Index
20022019
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  • 12 Similar Profiles
Induced Pluripotent Stem Cells Medicine & Life Sciences
Stem Cells Medicine & Life Sciences
Regenerative Medicine Medicine & Life Sciences
Pluripotent Stem Cells Medicine & Life Sciences
Stem cells Chemical Compounds
Embryonic Stem Cells Medicine & Life Sciences
Cardiac Myocytes Medicine & Life Sciences
Regeneration Medicine & Life Sciences

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Projects 2010 2015

Dysfunctional regeneration in cardiomyopathy: iPS-based diagnosis and therapy

Nelson, T. J.

National Institutes of Health

9/30/10 → 6/30/15

Project: Research project

Cardiomyopathies
Regeneration
Stem Cells
Induced Pluripotent Stem Cells
Myocardium

Research Output 2002 2019

  • 3070 Citations
  • 29 Scopus h-Index
  • 84 Article
  • 3 Chapter
  • 3 Review article
  • 1 Comment/debate
2 Citations (Scopus)

Altered serotonergic circuitry in SSRI-resistant major depressive disorder patient-derived neurons

Vadodaria, K. C., Ji, Y., Skime, M., Paquola, A. C., Nelson, T. J., Hall-Flavin, D., Heard, K. J., Fredlender, C., Deng, Y., Elkins, J., Dani, K., Le, A. T., Marchetto, M. C., Weinshilboum, R. M. & Gage, F. H., Jan 1 2019, In : Molecular Psychiatry.

Research output: Contribution to journal › Article

Major Depressive Disorder
Serotonin Uptake Inhibitors
Serotonergic Neurons
Neurons
Induced Pluripotent Stem Cells
1 Citation (Scopus)

Serotonin-induced hyperactivity in SSRI-resistant major depressive disorder patient-derived neurons

Vadodaria, K. C., Ji, Y., Skime, M., Paquola, A., Nelson, T. J., Hall-Flavin, D., Fredlender, C., Heard, K. J., Deng, Y., Le, A. T., Dave, S., Fung, L., Li, X., Marchetto, M. C., Weinshilboum, R. M. & Gage, F. H., Jan 1 2019, In : Molecular Psychiatry.

Research output: Contribution to journal › Article

Major Depressive Disorder
Serotonin Uptake Inhibitors
Serotonin
Neurons
Synaptic Transmission

Single-Cell RNA-Sequencing and Optical Electrophysiology of Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes Reveal Discordance between Cardiac Subtype-Associated Gene Expression Patterns and Electrophysiological Phenotypes

Biendarra-Tiegs, S. M., Li, X., Ye, D., Brandt, E. B., Ackerman, M. J. & Nelson, T. J., May 15 2019, In : Stem Cells and Development. 28, 10, p. 659-673 15 p.

Research output: Contribution to journal › Article

Open Access
RNA Sequence Analysis
Induced Pluripotent Stem Cells
Electrophysiology
Cardiac Myocytes
Phenotype

Studying treatment resistance in depression using patient derived neurons in vitro

Vadodaria, K. C., Ji, Y., Skime, M., Paquola, A., Nelson, T. J., Hall-Flavin, D., Fredlender, C., Heard, K. J., Deng, Y., Le, A. T., Dave, S., Fung, L., Li, X., Marchetto, M. C., Weinshilboum, R. M. & Gage, F. H., Jun 1 2019, In : Molecular Psychiatry. 24, 6, 1 p.

Research output: Contribution to journal › Comment/debate

Neurons
Therapeutics
In Vitro Techniques
11 Citations (Scopus)

Current Interventional and Surgical Management of Congenital Heart Disease: Specific Focus on Valvular Disease and Cardiac Arrhythmias

Holst, K. A., Said, S. M., Nelson, T. J., Cannon, B. C. & Dearani, J. A., Mar 17 2017, In : Circulation Research. 120, 6, p. 1027-1044 18 p.

Research output: Contribution to journal › Review article

Cardiac Arrhythmias
Heart Diseases
Thoracic Surgery
Critical Care
Reoperation