Research Output per year
Fingerprint Dive into the research topics where Takahisa Kanekiyo is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
- 4 Similar Profiles
Alzheimer Disease
Medicine & Life Sciences
Amyloid
Medicine & Life Sciences
Apolipoproteins E
Medicine & Life Sciences
Brain
Medicine & Life Sciences
Lipoprotein Receptors
Medicine & Life Sciences
Low Density Lipoprotein Receptor-Related Protein-1
Medicine & Life Sciences
prostaglandin R2 D-isomerase
Medicine & Life Sciences
Astrocytes
Medicine & Life Sciences
Network
Recent external collaboration on country level. Dive into details by clicking on the dots.
Projects
Reverse apoE4 effects by apoE2 expression in Alzheimer's disease
Project: Research project
Brain Neurotropic Growth Factor Delivery to Prevent and Treat Alzheimer?s Disease
Project: Research project
Research Output 2005 2019
5-HT3 antagonist ondansetron increases apoE secretion by modulating the LXR-ABCA1 pathway
Shinohara, M., Shinohara, M., Zhao, J., Fu, Y., Liu, C-C., Kanekiyo, T. & Bu, G. D., Mar 2 2019, In : International Journal of Molecular Sciences. 20, 6, 1488.Research output: Contribution to journal › Article
Open Access
Serotonin 5-HT3 Receptor Antagonists
Ondansetron
secretions
Apolipoproteins E
liver
ABCA7 haplodeficiency disturbs microglial immune responses in the mouse brain
Aikawa, T., Ren, Y., Yamazaki, Y., Tachibana, M., Johnson, M. R., Anderson, C. T., Martens, Y. A., Holm, M. L., Asmann, Y. W., Saito, T., Saido, T. C., Fitzgerald, M. L., Bu, G. & Kanekiyo, T., Jan 1 2019, In : Proceedings of the National Academy of Sciences of the United States of America. 116, 47, p. 23790-23796 7 p.Research output: Contribution to journal › Article
Alzheimer Disease
Amyloid
Brain
Nonsense Codon
Microglia
ApoE-2 Brain-Targeted Gene Therapy Through Transferrin and Penetratin Tagged Liposomal Nanoparticles
Dos Santos Rodrigues, B., Kanekiyo, T. & Singh, J., Sep 16 2019, In : Pharmaceutical research. 36, 11, 1 p.Research output: Contribution to journal › Article
Gene therapy
Apolipoproteins E
Transferrin
Liposomes
Genetic Therapy
4
Citations
(Scopus)
APOE4-mediated amyloid-β pathology depends on its neuronal receptor LRP1
Tachibana, M., Holm, M. L., Liu, C-C., Shinohara, M., Aikawa, T., Oue, H., Yamazaki, Y., Martens, Y. A., Murray, M. E., Sullivan, P. M., Weyer, K., Glerup, S., Dickson, D. W., Bu, G. D. & Kanekiyo, T., Mar 1 2019, In : Journal of Clinical Investigation. 129, 3, p. 1272-1277 6 p.Research output: Contribution to journal › Article
LDL Receptors
Amyloid
Apolipoprotein E4
Pathology
Alzheimer Disease
Corrigendum to “Modulation of mitochondrial complex I activity averts cognitive decline in multiple animal models of familial Alzheimer's disease” [EBioMedicine 2 (2015) 294–305] (Modulation of Mitochondrial Complex I Activity Averts Cognitive Decline in Multiple Animal Models of Familial Alzheimer's Disease (2015) 2(4) (294–305), (S2352396415000729), (10.1016/j.ebiom.2015.03.009))
Zhang, L., Zhang, S., Maezawa, I., Trushin, S., Minhas, P., Pinto, M., Jin, L. W., Prasain, K., Nguyen, T. D. T., Yamazaki, Y., Kanekiyo, T., Bu, G. D., Gateno, B., Chang, K. O., Nath, K. A., Nemutlu, E., Dzeja, P. P., Pang, Y-P., Hua, D. H. & Trushina, E. D., Apr 1 2019, In : EBioMedicine. 42, 1 p.Research output: Contribution to journal › Comment/debate
Open Access
Brain
Alzheimer Disease
Animals
Animal Models
Modulation