• 45551 Citations
  • 100 Scopus h-Index
1978 …2021
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Research Output 1978 2019

  • 45551 Citations
  • 100 Scopus h-Index
  • 491 Article
  • 4 Chapter
  • 4 Comment/debate
  • 1 Review article
2013
38 Citations (Scopus)

Integrated analysis of genome-wide copy number alterations and gene expression in microsatellite stable, CpG island methylator phenotype-negative colon cancer

Loo, L. W. M., Tiirikainen, M., Cheng, I., Lum-Jones, A., Seifried, A., Church, J. M., Gryfe, R., Weisenberger, D. J., Lindor, N. M., Gallinger, S., Haile, R. W., Duggan, D. J., Thibodeau, S. N., Casey, G. & Le Marchand, L., May 2013, In : Genes Chromosomes and Cancer. 52, 5, p. 450-466 17 p.

Research output: Contribution to journalArticle

CpG Islands
Microsatellite Repeats
Colonic Neoplasms
Genome
Phenotype
56 Citations (Scopus)

Multiple Genetic Variant Association Testing by Collapsing and Kernel Methods With Pedigree or Population Structured Data

Schaid, D. J., Mcdonnell, S. K., Sinnwell, J. P. & Thibodeau, S. N., Jul 2013, In : Genetic Epidemiology. 37, 5, p. 409-418 10 p.

Research output: Contribution to journalArticle

Pedigree
Population
Linkage Disequilibrium
X Chromosome
Rare Diseases
53 Citations (Scopus)

Mutation-specific antibody detects mutant BRAFV600E protein expression in human colon carcinomas

Sinicrope, F. A., Smyrk, T. C., Tougeron, D., Thibodeau, S. N., Singh, S., Muranyi, A., Shanmugam, K., Grogan, T. M., Alberts, S. R. & Shi, Q. D., Aug 1 2013, In : Cancer. 119, 15, p. 2765-2770 6 p.

Research output: Contribution to journalArticle

Mutant Proteins
Colon
Carcinoma
Mutation
Antibodies
134 Citations (Scopus)

Prognostic impact of deficient DNA mismatch repair in patients with stage III colon cancer from a randomized trial of FOLFOX-based adjuvant chemotherapy.

Sinicrope, F. A., Mahoney, M. R., Smyrk, T. C., Thibodeau, S. N., Warren, R. S., Bertagnolli, M. M., Nelson, G. D., Goldberg, R. M., Sargent, D. J. & Alberts, S. R., Oct 10 2013, In : Journal of clinical oncology : official journal of the American Society of Clinical Oncology. 31, 29, p. 3664-3672 9 p.

Research output: Contribution to journalArticle

DNA Repair-Deficiency Disorders
DNA Mismatch Repair
Adjuvant Chemotherapy
Colonic Neoplasms
Neoplasms
67 Citations (Scopus)

Telomere length varies by DNA extraction method: Implications for epidemiologic research

Cunningham, J. M., Johnson, R. A., Litzelman, K., Skinner, H. G., Seo, S., Engelman, C. D., Vanderboom, R. J., Kimmel, G. W., Gangnon, R. E., Riegert-Johnson, D. L., Baron, J. A., Potter, J. D., Haile, R., Buchanan, D. D., Jenkins, M. A., Rider, D. N., Thibodeau, S. N., Petersen, G. M. & Boardman, L. A., Nov 2013, In : Cancer Epidemiology Biomarkers and Prevention. 22, 11, p. 2047-2054 8 p.

Research output: Contribution to journalArticle

Epidemiologic Methods
Telomere
DNA
Research
Chloroform
96 Citations (Scopus)

The mayo clinic biobank: A building block for individualized medicine

Olson, J. E., Ryu, E., Johnson, K. J., Koenig, B. A., Maschke, K. J., Morrisette, J. A., Liebow, M., Takahashi, P. Y., Fredericksen, Z. S., Sharma, R. G., Anderson, K. S., Hathcock, M. A., Carnahan, J. A., Pathak, J., Lindor, N. M., Beebe, T. J., Thibodeau, S. N. & Cerhan, J. R., 2013, In : Mayo Clinic Proceedings. 88, 9, p. 952-962 11 p.

Research output: Contribution to journalArticle

Precision Medicine
Electronic Health Records
Skin Neoplasms
Gastroesophageal Reflux
Hyperlipidemias
2012
4 Citations (Scopus)

Analysis of Xq27-28 linkage in the international consortium for prostate cancer genetics (ICPCG) families

Bailey-Wilson, J. E., Childs, E. J., Cropp, C. D., Schaid, D. J., Xu, J., Camp, N. J., Cannon-Albright, L. A., Farnham, J. M., George, A., Powell, I., Carpten, J. D., Giles, G. G., Hopper, J. L., Severi, G., English, D. R., Foulkes, W. D., Mæhle, L., Møller, P., Eeles, R., Easton, D. & 32 others, Guy, M., Edwards, S., Badzioch, M. D., Whittemore, A. S., Oakley-Girvan, I., Hsieh, C. L., Dimitrov, L., Stanford, J. L., Karyadi, D. M., Deutsch, K., McIntosh, L., Ostrander, E. A., Wiley, K. E., Isaacs, S. D., Walsh, P. C., Thibodeau, S. N., McDonnell, S. K., Hebbring, S., Lange, E. M., Cooney, K. A., Tammela, T. L. J., Schleutker, J., Maier, C., Bochum, S., Hoegel, J., Grönberg, H., Wiklund, F., Emanuelsson, M., Cancel-Tassin, G., Valeri, A., Cussenot, O. & Isaacs, W. B., Jun 19 2012, In : BMC Medical Genetics. 13, 46.

Research output: Contribution to journalArticle

Prostatic Neoplasms
Lod Score
Age of Onset
X Chromosome
Meta-Analysis
8 Citations (Scopus)

An American founder mutation in MLH1

Tomsic, J., Liyanarachchi, S., Hampel, H., Morak, M., Thomas, B. C., Raymond, V. M., Chittenden, A., Schackert, H. K., Gruber, S. B., Syngal, S., Viel, A., Holinski-Feder, E., Thibodeau, S. N. & De La Chapelle, A., May 1 2012, In : International Journal of Cancer. 130, 9, p. 2088-2095 8 p.

Research output: Contribution to journalArticle

Hereditary Nonpolyposis Colorectal Neoplasms
Mutation
Haplotypes
Italy
Confidence Intervals
22 Citations (Scopus)

Associations between intake of folate and related micronutrients with molecularly defined colorectal cancer risks in the Iowa Women's Health Study

Razzak, A. A., Oxentenko, A. S., Vierkant, R. A., Tillmans, L. S., Wang, A. H., Weisenberger, D. J., Laird, P. W., Lynch, C. F., Anderson, K. E., French, A. J., Haile, R. W., Harnack, L. J., Potter, J. D., Slager, S. L., Smyrk, T. C., Thibodeau, S. N., Cerhan, J. R. & Limburg, P. J., Oct 1 2012, In : Nutrition and Cancer. 64, 7, p. 899-910 12 p.

Research output: Contribution to journalArticle

Micronutrients
Women's Health
Folic Acid
Colorectal Neoplasms
Methionine
10 Citations (Scopus)

Chromosomes 4 and 8 implicated in a genome wide SNP linkage scan of 762 prostate cancer families collected by the ICPCG

Lu, L., Cancel-Tassin, G., Valeri, A., Cussenot, O., Lange, E. M., Cooney, K. A., Farnham, J. M., Camp, N. J., Cannon-Albright, L. A., Tammela, T. L. J., Schleutker, J., Hoegel, J., Herkommer, K., Maier, C., Vogel, W., Wiklund, F., Emanuelsson, M., Grönberg, H., Wiley, K. E., Isaacs, S. D. & 38 others, Walsh, P. C., Helfand, B. T., Kan, D., Catalona, W. J., Stanford, J. L., Fitzgerald, L. M., Johanneson, B., Deutsch, K., McIntosh, L., Ostrander, E. A., Thibodeau, S. N., McDonnell, S. K., Hebbring, S., Schaid, D. J., Whittemore, A. S., Oakley-Girvan, I., Hsieh, C. L., Powell, I., Bailey-Wilson, J. E., Cropp, C. D., Simpson, C., Carpten, J. D., Seminara, D., Zheng, S. L., Xu, J., Giles, G. G., Severi, G., Hopper, J. L., English, D. R., Foulkes, W. D., Maehle, L., Moller, P., Badzioch, M. D., Edwards, S., Guy, M., Eeles, R., Easton, D. & Isaacs, W. B., Mar 2012, In : Prostate. 72, 4, p. 410-426 17 p.

Research output: Contribution to journalArticle

Chromosomes, Human, Pair 8
Chromosomes, Human, Pair 4
Single Nucleotide Polymorphism
Prostatic Neoplasms
Genome
25 Citations (Scopus)

Cigarette smoking and colorectal cancer risk by KRAS mutation status among older women

Samadder, N. J., Vierkant, R. A., Tillmans, L. S., Wang, A. H., Lynch, C. F., Anderson, K. E., French, A. J., Haile, R. W., Harnack, L. J., Potter, J. D., Slager, S. L., Smyrk, T. C., Thibodeau, S. N., Cerhan, J. R. & Limburg, P. J., May 2012, In : American Journal of Gastroenterology. 107, 5, p. 782-789 8 p.

Research output: Contribution to journalArticle

Colorectal Neoplasms
Smoking
Mutation
Women's Health
Neoplasms
44 Citations (Scopus)

Cis-expression QTL analysis of established colorectal cancer risk variants in colon tumors and adjacent normal tissue

Loo, L. W. M., Cheng, I., Tiirikainen, M., Lum-Jones, A., Seifried, A., Dunklee, L. M., Church, J. M., Gryfe, R., Weisenberger, D. J., Haile, R. W., Gallinger, S., Duggan, D. J., Thibodeau, S. N., Casey, G. & Marchand, L. L., Feb 17 2012, In : PLoS One. 7, 2, e30477.

Research output: Contribution to journalArticle

colorectal neoplasms
colon
Tumors
Colorectal Neoplasms
quantitative trait loci
186 Citations (Scopus)

Colorectal and other cancer risks for carriers and noncarriers from families with a DNA mismatch repair gene mutation: A prospective cohort study

Win, A. K., Young, J. P., Lindor, N. M., Tucker, K. M., Ahnen, D. J., Young, G. P., Buchanan, D. D., Clendenning, M., Giles, G. G., Winship, I., Macrae, F. A., Goldblatt, J., Southey, M. C., Arnold, J., Thibodeau, S. N., Gunawardena, S. R., Bapat, B., Baron, J. A., Casey, G., Gallinger, S. & 5 others, Le Marchand, L., Newcomb, P. A., Haile, R. W., Hopper, J. L. & Jenkins, M. A., Mar 20 2012, In : Journal of Clinical Oncology. 30, 9, p. 958-964 7 p.

Research output: Contribution to journalArticle

DNA Mismatch Repair
Colorectal Neoplasms
Cohort Studies
Prospective Studies
Mutation
18 Citations (Scopus)

Colorectal cancer linkage on chromosomes 4q21, 8q13, 12q24, and 15q22

Cicek, M., Cunningham, J. M., Fridley, B. L., Serie, D. J., Bamlet, W. R., Diergaarde, B., Haile, R. W., Le Marchand, L., Krontiris, T. G., Younghusband, H. B., Gallinger, S., Newcomb, P. A., Hopper, J. L., Jenkins, M. A., Casey, G., Schumacher, F., Chen, Z., DeRycke, M. S., Templeton, A. S., Winship, I. & 13 others, Green, R. C., Green, J. S., Macrae, F. A., Parry, S., Young, G. P., Young, J. P., Buchanan, D., Thomas, D. C., Bishop, D. T., Lindor, N. M., Thibodeau, S. N., Potter, J. D. & Goode, E. L., May 31 2012, In : PLoS One. 7, 5, e38175.

Research output: Contribution to journalArticle

DNA Mismatch Repair
Chromosomes
colorectal neoplasms
linkage (genetics)
Colorectal Neoplasms
301 Citations (Scopus)

Effect of oxaliplatin, fluorouracil, and leucovorin with or without cetuximab on survival among patients with resected stage III colon cancer: A randomized trial

Alberts, S. R., Sargent, D. J., Nair, S., Mahoney, M. R., Mooney, M., Thibodeau, S. N., Smyrk, T. C., Sinicrope, F. A., Chan, E., Gill, S., Kahlenberg, M. S., Shields, A. F., Quesenberry, J. T., Webb, T. A., Farr, G. H., Pockaj, B. A., Grothey, A. F. & Goldberg, R. M., Mar 28 2012, In : JAMA - Journal of the American Medical Association. 307, 13, p. 1383-1393 11 p.

Research output: Contribution to journalArticle

oxaliplatin
Leucovorin
Fluorouracil
Colonic Neoplasms
Survival
225 Citations (Scopus)

Identification of Lynch syndrome among patients with colorectal cancer

Moreira, L., Balaguer, F., Lindor, N. M., De La Chapelle, A., Hampel, H., Aaltonen, L. A., Hopper, J. L., Le Marchand, L., Gallinger, S., Newcomb, P. A., Haile, R., Thibodeau, S. N., Gunawardena, S., Jenkins, M. A., Buchanan, D. D., Potter, J. D., Baron, J. A., Ahnen, D. J., Moreno, V., Andreu, M. & 3 others, De Leon, M. P., Rustgi, A. K. & Castells, A., Oct 17 2012, In : JAMA - Journal of the American Medical Association. 308, 15, p. 1555-1565 11 p.

Research output: Contribution to journalArticle

Hereditary Nonpolyposis Colorectal Neoplasms
DNA Mismatch Repair
Colorectal Neoplasms
Neoplasms
Guidelines
49 Citations (Scopus)

Immunohistochemical testing of conventional adenomas for loss of expression of mismatch repair proteins in Lynch syndrome mutation carriers: A case series from the Australasian site of the colon cancer family registry

Walsh, M. D., Buchanan, D. D., Pearson, S. A., Clendenning, M., Jenkins, M. A., Win, A. K., Walters, R. J., Spring, K. J., Nagler, B., Pavluk, E., Arnold, S. T., Goldblatt, J., George, J., Suthers, G. K., Phillips, K., Hopper, J. L., Jass, J. R., Baron, J. A., Ahnen, D. J., Thibodeau, S. N. & 5 others, Lindor, N. M., Parry, S., Walker, N. I., Rosty, C. & Young, J. P., May 2012, In : Modern Pathology. 25, 5, p. 722-730 9 p.

Research output: Contribution to journalArticle

Hereditary Nonpolyposis Colorectal Neoplasms
DNA Mismatch Repair
Adenoma
Colonic Neoplasms
Registries
3 Citations (Scopus)

Multiple jejunal cancers resulting from combination of germline APC and MLH1 mutations

Lindor, N. M., Smyrk, T. C., Buehler, S., Gunawardena, S. R., Thomas, B. C., Limburg, P. J., Kirmani, S. & Thibodeau, S. N., Dec 2012, In : Familial Cancer. 11, 4, p. 667-669 3 p.

Research output: Contribution to journalArticle

Jejunal Neoplasms
Heterozygote
Phenotype
Mutation
Adenomatous Polyposis Coli
15 Citations (Scopus)

Mutations of SMAD4 account for both LAPS and Myhre syndromes

Lindor, N. M., Gunawardena, S. R. & Thibodeau, S. N., Jun 2012, In : American Journal of Medical Genetics, Part A. 158 A, 6, p. 1520-1521 2 p.

Research output: Contribution to journalArticle

Congenital Hand Deformities
Smad4 Protein
Growth Disorders
Cryptorchidism
Joint Diseases
184 Citations (Scopus)

Next-generation stool DNA test accurately detects colorectal cancer and large adenomas

Ahlquist, D. A., Zou, H., Domanico, M., Mahoney, D. W., Yab, T. C., Taylor, W. R., Butz, M. L., Thibodeau, S. N., Rabeneck, L., Paszat, L. F., Kinzler, K. W., Vogelstein, B., Bjerregaard, N. C., Laurberg, S., Sørensen, H. T., Berger, B. M. & Lidgard, G. P., Feb 2012, In : Gastroenterology. 142, 2, p. 248-256 9 p.

Research output: Contribution to journalArticle

Adenoma
Colorectal Neoplasms
DNA
ROC Curve
Case-Control Studies
24 Citations (Scopus)

Postmenopausal hormone therapy and colorectal cancer risk by molecularly defined subtypes among older women

Limsui, D., Vierkant, R. A., Tillmans, L. S., Wang, A. H., Weisenberger, D. J., Laird, P. W., Lynch, C. F., Anderson, K. E., French, A. J., Haile, R. W., Harnack, L. J., Potter, J. D., Slager, S. L., Smyrk, T. C., Thibodeau, S. N., Cerhan, J. R. & Limburg, P. J., Sep 2012, In : Gut. 61, 9, p. 1299-1305 7 p.

Research output: Contribution to journalArticle

Colorectal Neoplasms
Hormones
Women's Health
Therapeutics
Neoplasms
18 Citations (Scopus)

Postmenopausal hormone therapy and colorectal cancer risk in relation to somatic KRAS mutation status among older women

Limburg, P. J., Limsui, D., Vierkant, R. A., Tillmans, L. S., Wang, A. H., Lynch, C. F., Anderson, K. E., French, A. J., Haile, R. W., Harnack, L. J., Potter, J. D., Slager, S. L., Smyrk, T. C., Thibodeau, S. N. & Cerhan, J. R., Apr 2012, In : Cancer Epidemiology Biomarkers and Prevention. 21, 4, p. 681-684 4 p.

Research output: Contribution to journalArticle

Colorectal Neoplasms
Hormones
Mutation
Confidence Intervals
Women's Health
88 Citations (Scopus)

The Stool DNA Test Is More Accurate Than the Plasma Septin 9 Test in Detecting Colorectal Neoplasia

Ahlquist, D. A., Taylor, W. R., Mahoney, D. W., Zou, H., Domanico, M., Thibodeau, S. N., Boardman, L. A., Berger, B. M. & Lidgard, G. P., Mar 2012, In : Clinical Gastroenterology and Hepatology. 10, 3

Research output: Contribution to journalArticle

Septins
Colorectal Neoplasms
Confidence Intervals
DNA
Adenoma
14 Citations (Scopus)

Validation of prostate cancer risk-related loci identified from genome-wide association studies using family-based association analysis: Evidence from the International Consortium for Prostate Cancer Genetics (ICPCG)

Jin, G., Lu, L., Cooney, K. A., Ray, A. M., Zuhlke, K. A., Lange, E. M., Cannon-Albright, L. A., Camp, N. J., Teerlink, C. C., Fitzgerald, L. M., Stanford, J. L., Wiley, K. E., Isaacs, S. D., Walsh, P. C., Foulkes, W. D., Giles, G. G., Hopper, J. L., Severi, G., Eeles, R., Easton, D. & 25 others, Kote-Jarai, Z., Guy, M., Rinckleb, A., Maier, C., Vogel, W., Cancel-Tassin, G., Egrot, C., Cussenot, O., Thibodeau, S. N., McDonnell, S. K., Schaid, D. J., Wiklund, F., Grönberg, H., Emanuelsson, M., Whittemore, A. S., Oakley-Girvan, I., Hsieh, C. L., Wahlfors, T., Tammela, T., Schleutker, J., Catalona, W. J., Zheng, S. L., Ostrander, E. A., Isaacs, W. B. & Xu, J., Jul 2012, In : Human Genetics. 131, 7, p. 1095-1103 9 p.

Research output: Contribution to journalArticle

Genome-Wide Association Study
Prostatic Neoplasms
Cerebral Palsy
Single Nucleotide Polymorphism
Parents
2011
15 Citations (Scopus)

Alcohol intake and colorectal cancer risk by molecularly defined subtypes in a prospective study of older women

Razzak, A. A., Oxentenko, A. S., Vierkant, R. A., Tillmans, L. S., Wang, A. H., Weisenberger, D. J., Laird, P. W., Lynch, C. F., Anderson, K. E., French, A. J., Haile, R. W., Harnack, L. J., Slager, S. L., Smyrk, T. C., Thibodeau, S. N., Cerhan, J. R. & Limburg, P. J., Dec 2011, In : Cancer Prevention Research. 4, 12, p. 2035-2043 9 p.

Research output: Contribution to journalArticle

Colorectal Neoplasms
Alcohols
Prospective Studies
Confidence Intervals
Microsatellite Instability
31 Citations (Scopus)

Body mass index in early adulthood and colorectal cancer risk for carriers and non-carriers of germline mutations in DNA mismatch repair genes

Win, A. K., Dowty, J. G., English, D. R., Campbell, P. T., Young, J. P., Winship, I., MacRae, F. A., Lipton, L., Parry, S., Young, G. P., Buchanan, D. D., Martínez, M. E., Jacobs, E. T., Ahnen, D. J., Haile, R. W., Casey, G., Baron, J. A., Lindor, N. M., Thibodeau, S. N., Newcomb, P. A. & 5 others, Potter, J. D., Le Marchand, L., Gallinger, S., Hopper, J. L. & Jenkins, M. A., Jun 28 2011, In : British Journal of Cancer. 105, 1, p. 162-169 8 p.

Research output: Contribution to journalArticle

DNA Mismatch Repair
Germ-Line Mutation
Colorectal Neoplasms
Body Mass Index
Mutation
19 Citations (Scopus)

Body mass index in early adulthood and endometrial cancer risk for mismatch repair gene mutation carriers

Win, A. K., Dowty, J. G., Antill, Y. C., English, D. R., Baron, J. A., Young, J. P., Giles, G. G., Southey, M. C., Winship, I., Lipton, L., Parry, S., Thibodeau, S. N., Haile, R. W., Gallinger, S., Le Marchand, L., Lindor, N. M., Newcomb, P. A., Hopper, J. L. & Jenkins, M. A., Apr 2011, In : Obstetrics and Gynecology. 117, 4, p. 899-905 7 p.

Research output: Contribution to journalArticle

DNA Mismatch Repair
Endometrial Neoplasms
Body Mass Index
Mutation
Genes
21 Citations (Scopus)

Characterization of two Ashkenazi Jewish founder mutations in MSH6 gene causing Lynch syndrome

Raskin, L., Schwenter, F., Freytsis, M., Tischkowitz, M., Wong, N., Chong, G., Narod, S. A., Levine, D. A., Bogomolniy, F., Aronson, M., Thibodeau, S. N., Hunt, K. S., Rennert, G., Gallinger, S., Gruber, S. B. & Foulkes, W. D., Jun 2011, In : Clinical Genetics. 79, 6, p. 512-522 11 p.

Research output: Contribution to journalArticle

Hereditary Nonpolyposis Colorectal Neoplasms
Endometrial Neoplasms
Mutation
Colorectal Neoplasms
Genes
21 Citations (Scopus)

Determining the frequency of de novo germline mutations in DNA mismatch repair genes

Win, A. K. O., Jenkins, M. A., Buchanan, D. D., Clendenning, M., Young, J. P., Giles, G. G., Goldblatt, J., Leggett, B. A., Hopper, J. L., Thibodeau, S. N. & Lindor, N. M., Aug 2011, In : Journal of Medical Genetics. 48, 8, p. 530-534 5 p.

Research output: Contribution to journalArticle

DNA Mismatch Repair
Germ-Line Mutation
Mutation
Genes
Hereditary Nonpolyposis Colorectal Neoplasms
293 Citations (Scopus)

DNA mismatch repair status and colon cancer recurrence and survival in clinical trials of 5-fluorouracil-based adjuvant therapy

Sinicrope, F. A., Foster, N. R., Thibodeau, S. N., Marsoni, S., Monges, G., Labianca, R., Yothers, G., Allegra, C., Moore, M. J., Gallinger, S. & Sargent, D. J., 2011, In : Journal of the National Cancer Institute. 103, 11, p. 863-875 13 p.

Research output: Contribution to journalArticle

DNA Mismatch Repair
Fluorouracil
Colonic Neoplasms
Clinical Trials
Recurrence

Erratum: DNA Mismatch Repair Status and Colon Cancer Recurrence and Survival in Clinical Trials of 5-Fluorouracil-Based Adjuvant Therapy (Journal of the National Cancer Institute (2011) 103:11 (863-875))

Sinicrope, F. A., Foster, N. R., Thibodeau, S. N., Marsoni, S., Monges, G., Labianca, R., Kim, G. P., Yothers, G., Allegra, C., Moore, M. J., Gallinger, S. & Sargent, D. J., Nov 2 2011, In : Journal of the National Cancer Institute. 103, 21, p. 1639 1 p.

Research output: Contribution to journalArticle

DNA Mismatch Repair
National Cancer Institute (U.S.)
Fluorouracil
Colonic Neoplasms
Clinical Trials
54 Citations (Scopus)

Frequency of deletions of EPCAM (TACSTD1) in MSH2-associated Lynch syndrome cases

Rumilla, K., Schowalter, K. V., Lindor, N. M., Thomas, B. C., Mensink, K. A., Gallinger, S., Holter, S., Newcomb, P. A., Potter, J. D., Jenkins, M. A., Hopper, J. L., Long, T. I., Weisenberger, D. J., Haile, R. W., Casey, G., Laird, P. W., Le Marchand, L. & Thibodeau, S. N., Jan 2011, In : Journal of Molecular Diagnostics. 13, 1, p. 93-99 7 p.

Research output: Contribution to journalArticle

Hereditary Nonpolyposis Colorectal Neoplasms
Germ-Line Mutation
Mutation
Methylation
DNA Repair Enzymes
58 Citations (Scopus)

Frequent truncating mutation of TFAM induces mitochondrial DNA depletion and apoptotic resistance in microsatellite-unstable colorectal cancer

Guo, J., Zheng, L., Liu, W., Wang, X., Wang, Z., Wang, Z., French, A. J., Kang, D., Chen, L., Thibodeau, S. N. & Liu, W., Apr 15 2011, In : Cancer Research. 71, 8, p. 2978-2987 10 p.

Research output: Contribution to journalArticle

Mitochondrial DNA
Microsatellite Repeats
Colorectal Neoplasms
Microsatellite Instability
Mutation
13 Citations (Scopus)

Germline PKHD1 mutations are protective against colorectal cancer

Ward, C. J., Wu, Y., Johnson, R. A., Woollard, J. R., Bergstralh, E. J., Cicek, M., Bakeberg, J., Rossetti, S., Heyer, C. M., Petersen, G. M., Lindor, N. M., Thibodeau, S. N., Harris, P. C., Torres, V., Hogan, M. C. & Boardman, L. A., Mar 2011, In : Human Genetics. 129, 3, p. 345-349 5 p.

Research output: Contribution to journalArticle

Germ-Line Mutation
Colorectal Neoplasms
Mutation
Autosomal Recessive Polycystic Kidney
Adenocarcinoma
66 Citations (Scopus)

HEF1, a novel target of Wnt signaling, promotes colonic cell migration and cancer progression

Li, Y., Bavarva, J. H., Wang, Z., Guo, J., Qian, C., Thibodeau, S. N., Golemis, E. A. & Liu, W., Jun 9 2011, In : Oncogene. 30, 23, p. 2633-2643 11 p.

Research output: Contribution to journalArticle

Cell Movement
Catenins
Colorectal Neoplasms
Neoplasms
Carcinogenesis
52 Citations (Scopus)

Leukocyte DNA methylation signature differentiates pancreatic cancer patients from healthy controls

Pedersen, K. S., Bamlet, W. R., Oberg, A. L., De Andrade, M., Matsumoto, M. E., Tang, H., Thibodeau, S. N., Petersen, G. M. & Wang, L., 2011, In : PLoS One. 6, 3, e18223.

Research output: Contribution to journalArticle

pancreatic neoplasms
Methylation
DNA methylation
DNA Methylation
adenocarcinoma
43 Citations (Scopus)

Lynch syndrome-associated extracolonic tumors are rare in two extended families with the same EPCAM deletion

Lynch, H. T., Riegert-Johnson, D. L., Snyder, C., Lynch, J. F., Hagenkord, J., Boland, C. R., Rhees, J., Thibodeau, S. N., Boardman, L. A., Davies, J., Kuiper, R. P., Hoogerbrugge, N. & Ligtenberg, M. J. L., Oct 2011, In : American Journal of Gastroenterology. 106, 10, p. 1829-1836 8 p.

Research output: Contribution to journalArticle

Hereditary Nonpolyposis Colorectal Neoplasms
Neoplasms
Colorectal Neoplasms
Mutation
DNA Mismatch Repair
109 Citations (Scopus)

MiRNA expression in colon polyps provides evidence for a Multihit model of colon cancer

Oberg, A. L., French, A. J., Sarver, A. L., Subramanian, S., Morlan, B. W., Riska, S. M., Borralho, P. M., Cunningham, J. M., Boardman, L. A., Wang, L., Smyrk, T. C., Asmann, Y., Steer, C. J. & Thibodeau, S. N., 2011, In : PLoS One. 6, 6, e20465.

Research output: Contribution to journalArticle

DNA Mismatch Repair
Polyps
colorectal neoplasms
Colonic Neoplasms
colon
6 Citations (Scopus)

National cancer institute prostate cancer genetics workshop

Catalona, W. J., Bailey-Wilson, J. E., Camp, N. J., Chanock, S. J., Cooney, K. A., Easton, D. F., Eeles, R. A., FitzGerald, L. M., Freedman, M. L., Gudmundsson, J., Kittles, R. A., Margulies, E. H., McGuire, B. B., Ostrander, E. A., Rebbeck, T. R., Stanford, J. L., Thibodeau, S. N., Witte, J. S. & Isaacs, W. B., May 15 2011, In : Cancer Research. 71, 10, p. 3442-3446 5 p.

Research output: Contribution to journalArticle

National Cancer Institute (U.S.)
Prostatic Neoplasms
Education
Technology
Genetic Research
7 Citations (Scopus)

Pancreatic cancer and a novel MSH2 germline alteration

Lindor, N. M., Petersen, G. M., Spurdle, A. B., Thompson, B., Goldgar, D. E. & Thibodeau, S. N., Oct 2011, In : Pancreas. 40, 7, p. 1138-1140 3 p.

Research output: Contribution to journalArticle

Pancreatic Neoplasms
Hereditary Nonpolyposis Colorectal Neoplasms
DNA Mismatch Repair
Computer Simulation
Observational Studies
45 Citations (Scopus)

Prevalence of Alterations in DNA Mismatch Repair Genes in Patients With Young-Onset Colorectal Cancer

Limburg, P. J., Harmsen, W. S., Chen, H. H., Gallinger, S., Haile, R. W., Baron, J. A., Casey, G., Woods, M. O., Thibodeau, S. N. & Lindor, N. M., Jun 2011, In : Clinical Gastroenterology and Hepatology. 9, 6, p. 497-502 6 p.

Research output: Contribution to journalArticle

DNA Mismatch Repair
Colorectal Neoplasms
Confidence Intervals
Mutation
Hereditary Nonpolyposis Colorectal Neoplasms
62 Citations (Scopus)

Quality assessment and correlation of microsatellite instability and immunohistochemical markers among population- And clinic-based colorectal tumors: Results from the colon cancer family registry

Cicek, M., Lindor, N. M., Gallinger, S., Bapat, B., Hopper, J. L., Jenkins, M. A., Young, J., Buchanan, D., Walsh, M. D., Le Marchand, L., Burnett, T., Newcomb, P. A., Grady, W. M., Haile, R. W., Casey, G., Plummer, S. J., Krumroy, L. A., Baron, J. A. & Thibodeau, S. N., May 2011, In : Journal of Molecular Diagnostics. 13, 3, p. 271-283 13 p.

Research output: Contribution to journalArticle

Microsatellite Instability
Colonic Neoplasms
Registries
Colorectal Neoplasms
DNA Mismatch Repair
209 Citations (Scopus)

Seven prostate cancer susceptibility loci identified by a multi-stage genome-wide association study

Kote-Jarai, Z., Olama, A. A. A., Giles, G. G., Severi, G., Schleutker, J., Weischer, M., Campa, D., Riboli, E., Key, T., Gronberg, H., Hunter, D. J., Kraft, P., Thun, M. J., Ingles, S., Chanock, S., Albanes, D., Hayes, R. B., Neal, D. E., Hamdy, F. C., Donovan, J. L. & 111 others, Pharoah, P., Schumacher, F., Henderson, B. E., Stanford, J. L., Ostrander, E. A., Sorensen, K. D., Dörk, T., Andriole, G., Dickinson, J. L., Cybulski, C., Lubinski, J., Spurdle, A., Clements, J. A., Chambers, S., Aitken, J., Gardiner, R. A. F., Thibodeau, S. N., Schaid, D. J., John, E. M., Maier, C., Vogel, W., Cooney, K. A., Park, J. Y., Cannon-Albright, L., Brenner, H., Habuchi, T., Zhang, H. W., Lu, Y. J., Kaneva, R., Muir, K., Benlloch, S., Leongamornlert, D. A., Saunders, E. J., Tymrakiewicz, M., Mahmud, N., Guy, M., O'Brien, L. T., Wilkinson, R. A., Hall, A. L., Sawyer, E. J., Dadaev, T., Morrison, J., Dearnaley, D. P., Horwich, A., Huddart, R. A., Khoo, V. S., Parker, C. C., Van As, N., Woodhouse, C. J., Thompson, A., Christmas, T., Ogden, C., Cooper, C. S., Lophatonanon, A., Southey, M. C., Hopper, J. L., English, D. R., Wahlfors, T., Tammela, T. L. J., Klarskov, P., Nordestgaard, B. G., Røder, M. A., Tybjarg-Hansen, A., Bojesen, S. E., Travis, R., Canzian, F., Kaaks, R., Wiklund, F., Aly, M., Lindstrom, S., Diver, W. R., Gapstur, S., Stern, M. C., Corral, R., Virtamo, J., Cox, A., Haiman, C. A., Le Marchand, L., Fitzgerald, L., Kolb, S., Kwon, E. M., Karyadi, D. M., Ørntoft, T. F., Borre, M., Meyer, A., Serth, J., Yeager, M., Berndt, S. I., Marthick, J. R., Patterson, B., Wokolorczyk, D., Batra, J., Lose, F., McDonnell, S. K., Joshi, A. D., Shahabi, A., Rinckleb, A. E., Ray, A., Sellers, T. A., Lin, H. Y., Stephenson, R. A., Farnham, J., Muller, H., Rothenbacher, D., Tsuchiya, N., Narita, S., Cao, G. W., Slavov, C., Mitev, V., Easton, D. F. & Eeles, R. A., Aug 2011, In : Nature Genetics. 43, 8, p. 785-791 7 p.

Research output: Contribution to journalArticle

Genome-Wide Association Study
Prostatic Neoplasms
Single Nucleotide Polymorphism
Developed Countries
Neoplasms
127 Citations (Scopus)

The PREMM1,2,6 model predicts risk of MLH1, MSH2, and MSH6 germline mutations based on cancer history

Kastrinos, F., Steyerberg, E. W., Mercado, R., Balmaña, J., Holter, S., Gallinger, S., Siegmund, K. D., Church, J. M., Jenkins, M. A., Lindor, N. M., Thibodeau, S. N., Burbidge, L. A., Wenstrup, R. J. & Syngal, S., Jan 2011, In : Gastroenterology. 140, 1, p. 73-81 9 p.

Research output: Contribution to journalArticle

Germ-Line Mutation
Mutation
Confidence Intervals
DNA Mismatch Repair
Neoplasms
2010
20 Citations (Scopus)

Alpha-1-antitrypsin deficiency and smoking as risk factors for mismatch repair deficient colorectal cancer: A study from the colon cancer family registry

Lindor, N. M., Yang, P., Evans, I., Schowalter, K., De Andrade, M., Li, J., Jeavons, E., Peterson, G., Gallinger, S., Bapat, B., Hopper, J., Jass, J., Jenkins, M., Templeton, A., Potter, J., Newcomb, P. A., LeMarchand, L., Grove, J., Haile, R., Baron, J. & 3 others, Seminara, D., Limburg, P. & Thibodeau, S. N., Feb 2010, In : Molecular Genetics and Metabolism. 99, 2, p. 157-159 3 p.

Research output: Contribution to journalArticle

alpha 1-Antitrypsin Deficiency
alpha 1-Antitrypsin
DNA Mismatch Repair
Colonic Neoplasms
Registries
124 Citations (Scopus)

Case-control study of overweight, obesity, and colorectal cancer risk, overall and by tumor microsatellite instability status

Campbell, P. T., Jacobs, E. T., Ulrich, C. M., Figueiredo, J. C., Poynter, J. N., McLaughlin, J. R., Haile, R. W., Jacobs, E. J., Newcomb, P. A., Potter, J. D., Le Marchand, L., Green, R. C., Parfrey, P., Younghusband, H. B., Cotterchio, M., Gallinger, S., Jenkins, M. A., Hopper, J. L., Baron, J. A., Thibodeau, S. N. & 3 others, Lindor, N. M., Limburg, P. J. & Martínez, M. E., Mar 2010, In : Journal of the National Cancer Institute. 102, 6, p. 391-400 10 p.

Research output: Contribution to journalArticle

Microsatellite Instability
Case-Control Studies
Colorectal Neoplasms
Obesity
Odds Ratio
180 Citations (Scopus)

Cigarette smoking and colorectal cancer risk by molecularly defined subtypes

Limsui, D., Vierkant, R. A., Tillmans, L. S., Wang, A. H., Weisenberger, D. J., Laird, P. W., Lynch, C. F., Anderson, K. E., French, A. J., Haile, R. W., Harnack, L. J., Potter, J. D., Slager, S. L., Smyrk, T. C., Thibodeau, S. N., Cerhan, J. R. & Limburg, P. J., Jul 2010, In : Journal of the National Cancer Institute. 102, 14, p. 1012-1022 11 p.

Research output: Contribution to journalArticle

Microsatellite Instability
Colorectal Neoplasms
Smoking
Confidence Intervals
Mutation
784 Citations (Scopus)

Defective mismatch repair as a predictive marker for lack of efficacy of fluorouracil-based adjuvant therapy in colon cancer

Sargent, D. J., Marsoni, S., Monges, G., Thibodeau, S. N., Labianca, R., Hamilton, S. R., French, A. J., Kabat, B., Foster, N. R., Torri, V., Ribic, C., Grothey, A. F., Moore, M., Zaniboni, A., Seitz, J. F., Sinicrope, F. A. & Gallinger, S., Jul 10 2010, In : Journal of Clinical Oncology. 28, 20, p. 3219-3226 8 p.

Research output: Contribution to journalArticle

DNA Mismatch Repair
Fluorouracil
Colonic Neoplasms
Therapeutics
Disease-Free Survival
9 Citations (Scopus)

Estimation of genotype relative risks from pedigree data by retrospective likelihoods

Schaid, D. J., McDonnell, S. K., Riska, S. M., Carlson, E. E. & Thibodeau, S. N., May 2010, In : Genetic Epidemiology. 34, 4, p. 287-298 12 p.

Research output: Contribution to journalArticle

Pedigree
Genotype
Single Nucleotide Polymorphism
Genome-Wide Association Study
Case-Control Studies
13 Citations (Scopus)

Family-based association analysis of 42 hereditary prostate cancer families identifies the Apolipoprotein L3 region on chromosome 22q12 as a risk locus

Johanneson, B., McDonnell, S. K., Karyadi, D. M., Quignon, P., McIntosh, L., Riska, S. M., FitzGerald, L. M., Johnson, G., Deutsch, K., Williams, G., Tillmans, L. S., Stanford, J. L., Schaid, D. J., Thibodeau, S. N. & Ostrander, E. A., Jul 14 2010, In : Human Molecular Genetics. 19, 19, p. 3852-3862 11 p., ddq283.

Research output: Contribution to journalArticle

Apolipoproteins
Chromosomes
Single Nucleotide Polymorphism
Prostatic Neoplasms
Population Control