• 44957 Citations
  • 100 Scopus h-Index
1978 …2021
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Research Output 1978 2019

  • 44957 Citations
  • 100 Scopus h-Index
  • 487 Article
  • 4 Chapter
  • 3 Comment/debate
  • 1 Review article
2016
17 Citations (Scopus)

Chromatin interactions and candidate genes at ten prostate cancer risk loci

Du, M., Tillmans, L., Gao, J., Gao, P., Yuan, T., Dittmar, R. L., Song, W., Yang, Y., Sahr, N., Wang, T., Wei, G. H., Thibodeau, S. N. & Wang, L., Mar 16 2016, In : Scientific Reports. 6, 23202.

Research output: Contribution to journalArticle

Chromatin
Prostatic Neoplasms
Single Nucleotide Polymorphism
Quantitative Trait Loci
Genes
17 Citations (Scopus)

Comparison of Prediction Models for Lynch Syndrome among Individuals with Colorectal Cancer

Lynch Syndrome prediction model validation study group, Feb 1 2016, In : Journal of the National Cancer Institute. 108, 2, djv308.

Research output: Contribution to journalArticle

Hereditary Nonpolyposis Colorectal Neoplasms
Colorectal Neoplasms
Mutation
Population
Area Under Curve
29 Citations (Scopus)

Cross-cancer genome-wide analysis of lung, ovary, breast, prostate, and colorectal cancer reveals novel pleiotropic associations

Colorectal Transdisciplinary (CORECT) Study, Ovarian Cancer Association Consortium (OCAC), The PRACTICAL Consortium, Hereditary Breast and Ovarian Cancer Research Group Netherlands (HEBON), African American Breast Cancer Consortium (AABC) & African Ancestry Prostate Cancer Consortium (AAPC), Sep 1 2016, In : Cancer Research. 76, 17, p. 5103-5114 12 p.

Research output: Contribution to journalArticle

Ovarian Neoplasms
Colorectal Neoplasms
Lung Neoplasms
Prostatic Neoplasms
Genome
10 Citations (Scopus)

CYP24A1 variant modifies the association between use of oestrogen plus progestogen therapy and colorectal cancer risk

Garcia-Albeniz, X., Rudolph, A., Hutter, C., White, E., Lin, Y., Rosse, S. A., Figueiredo, J. C., Harrison, T. A., Jiao, S., Brenner, H., Casey, G., Hudson, T. J., Thornquist, M., Le Marchand, L., Potter, J., Slattery, M. L., Zanke, B., Baron, J. A., Caan, B. J., Chanock, S. J. & 36 others, Berndt, S. I., Stelling, D., Fuchs, C. S., Hoffmeister, M., Butterbach, K., Du, M., James Gauderman, W., Gunter, M. J., Lemire, M., Ogino, S., Lin, J., Hayes, R. B., Haile, R. W., Schoen, R. E., Warnick, G. S., Jenkins, M. A., Thibodeau, S. N., Schumacher, F. R., Lindor, N. M., Kolonel, L. N., Hopper, J. L., Gong, J., Seminara, D., Pflugeisen, B. M., Ulrich, C. M., Qu, C., Duggan, D., Cotterchio, M., Campbell, P. T., Carlson, C. S., Newcomb, P. A., Giovannucci, E., Hsu, L., Chan, A. T., Peters, U. & Chang-Claude, J., Jan 19 2016, In : British Journal of Cancer. 114, 2, p. 221-229 9 p.

Research output: Contribution to journalArticle

Progestins
Colorectal Neoplasms
Estrogens
Hormones
Therapeutics
9 Citations (Scopus)

Gene and pathway level analyses of germline DNA-repair gene variants and prostate cancer susceptibility using the iCOGS-genotyping array

Saunders, E. J., Dadaev, T., Leongamornlert, D. A., Al Olama, A. A., Benlloch, S., Giles, G. G., Wiklund, F., Grönberg, H., Haiman, C. A., Schleutker, J., Nordestgaard, BØ. G., Travis, R. C., Neal, D., Pasayan, N., Khaw, K. T., Stanford, J. L., Blot, W. J., Thibodeau, S. N., Maier, C., Kibel, A. S. & 13 others, Cybulski, C., Cannon-Albright, L., Brenner, H., Park, J. Y., Kaneva, R., Batra, J., Teixeira, M. R., Pandha, H., Govindasami, K., Muir, K., Easton, D. F., Eeles, R. A. & Kote-Jarai, Z., Apr 12 2016, In : British Journal of Cancer. 114, 8, p. 945-952 8 p.

Research output: Contribution to journalArticle

DNA Repair
Prostatic Neoplasms
Genes
Single Nucleotide Polymorphism
Genome
12 Citations (Scopus)

Genome-wide association of familial prostate cancer cases identifies evidence for a rare segregating haplotype at 8q24.21

The PRACTICAL Consortium & International Consortium for Prostate Cancer Genetics, Aug 1 2016, In : Human Genetics. 135, 8, p. 923-938 16 p.

Research output: Contribution to journalArticle

Haplotypes
Single Nucleotide Polymorphism
Genome
Genome-Wide Association Study
Prostatic Neoplasms
12 Citations (Scopus)

Genome-Wide Interaction Analyses between Genetic Variants and Alcohol Consumption and Smoking for Risk of Colorectal Cancer

CCFR and GECCO, Oct 1 2016, In : PLoS Genetics. 12, 10, e1006296.

Research output: Contribution to journalArticle

smoking
colorectal neoplasms
Alcohol Drinking
alcohol
Colorectal Neoplasms
56 Citations (Scopus)

Genome-wide meta-analyses of breast, ovarian, and prostate cancer association studies identify multiple new susceptibility loci shared by at least two cancer types

Kar, S. P., Beesley, J., Al Olama, A. A., Michailidou, K., Tyrer, J., Kote-Jarai, Z. A., Lawrenson, K., Lindstrom, S., Ramus, S. J., Thompson, D. J., Kibel, A. S., Dansonka-Mieszkowska, A., Michael, A., Dieffenbach, A. K., Gentry-Maharaj, A., Whittemore, A. S., Wolk, A., Monteiro, A., Peixoto, A., Kierzek, A. & 260 others, Cox, A., Rudolph, A., Gonzalez-Neira, A., Wu, A. H., Lindblom, A., Swerdlow, A., Ziogas, A., Ekici, A. B., Burwinkel, B., Karlan, B. Y., Nordestgaard, B. G., Blomqvist, C., Phelan, C., McLean, C., Pearce, C. L., Vachon, C. M., Cybulski, C., Slavov, C., Stegmaier, C., Maier, C., Ambrosone, C. B., Hogdall, C. K., Teerlink, C. C., Kang, D., Tessier, D. C., Schaid, D. J., Stram, D. O., Cramer, D. W., Neal, D. E., Eccles, D., Flesch-Janys, D., Velez Edwards, D. R., Wokozorczyk, D., Levine, D. A., Yannoukakos, D., Sawyer, E. J., Bandera, E. V., Poole, E. M., Goode, E. L., Khusnutdinova, E., Hogdall, E., Song, F., Bruinsma, F., Heitz, F., Modugno, F., Hamdy, F. C., Wiklund, F., Giles, G. G., Olsson, H., Wildiers, H., Ulmer, H. U., Pandha, H., Risch, H. A., Darabi, H., Salvesen, H. B., Nevanlinna, H., Gronberg, H., Brenner, H., Brauch, H., Anton-Culver, H., Song, H., Lim, H. Y., McNeish, I., Campbell, I., Vergote, I., Gronwald, J., Lubiński, J., Stanford, J. L., Benitez, J., Doherty, J. A., Permuth, J. B., Chang-Claude, J., Donovan, J. L., Dennis, J., Schildkraut, J. M., Schleutker, J., Hopper, J. L., Kupryjanczyk, J., Park, J. Y., Figueroa, J., Clements, J. A., Knight, J. A., Peto, J., Cunningham, J. M., Pow-Sang, J., Batra, J., Czene, K., Lu, K. H., Herkommer, K., Khaw, K. T., Matsuo, K., Muir, K., Offitt, K., Chen, K., Moysich, K. B., Aittomaki, K., Odunsi, K., Kiemeney, L. A., Massuger, L. F. A. G., Fitzgerald, L. M., Cook, L. S., Cannon-Albright, L., Hooning, M. J., Pike, M. C., Bolla, M. K., Luedeke, M., Teixeira, M. R., Goodman, M. T., Schmidt, M. K., Riggan, M., Aly, M., Rossing, M. A., Beckmann, M. W., Moisse, M., Sanderson, M., Southey, M. C., Jones, M., Lush, M., Hildebrandt, M. A. T., Hou, M. F., Schoemaker, M. J., Garcia-Closas, M., Bogdanova, N., Rahman, N., Le, N. D., Orr, N., Wentzensen, N., Pashayan, N., Peterlongo, P., Guenel, P., Brennan, P., Paulo, P., Webb, P. M., Broberg, P., Fasching, P. A., Devilee, P., Wang, Q., Cai, Q., Li, Q., Kaneva, R., Butzow, R., Kopperud, R. K., Schmutzler, R. K., Stephenson, R. A., Macinnis, R. J., Hoover, R. N., Winqvist, R., Ness, R., Milne, R. L., Travis, R. C., Benlloch, S., Olson, S. H., McDonnell, S. K., Tworoger, S. S., Maia, S., Berndt, S., Lee, S. C., Teo, S. H., Thibodeau, S. N., Bojesen, S. E., Gapstur, S. M., Kjar, S. K., Pejovic, T., Tammela, T. L. J., Eeles, A., Easton, D., Kote-Jarai, Z. S., Al Olama, A. A., Benlloch, S., Muir, K., Giles, G. G., Southey, M. C., Fitzgerald, L. M., Gronberg, H., Wiklund, F., Aly, M., Henderson, B. E., Schumacher, F., Haiman, C. A., Schleutker, J., Wahlfors, T., Tammela, T. L. J., Nordestgaard, B. G., Key, T. J., Travis, R. C., Neal, D. E., Donovan, J. L., Hamdy, F. C., Pharoah, P., Pashayan, N., Khaw, K. T., Stanford, J. L., Thibodeau, S. N., McDonnell, S. K., Schaid, D. J., Couch, F. J., Vogel, W., Luedeke, M., Herkommer, K., Kibel, A. S., Cybulski, C., Wokozorczyk, D., Kluzniak, W., Cannon-Albright, L., Brenner, H., Dieffenbach, A. K., Arndt, V., Park, J. Y., Sellers, T., Lim, H. Y., Slavov, C., Kaneva, R., Mitev, V., Batra, J., Spurdle, A., Teixeira, M. R., Paulo, P., Maia, S., Pandha, H., Michael, A., Kierzek, A., Dork, T., Bruning, T., Wahlfors, T., Key, T. J., Edwards, T. L., Menon, U., Hamann, U., Mitev, V., Kosma, V. M., Setiawan, V. W., Kristensen, V., Arndt, V., Vogel, W., Zheng, W., Sieh, W., Blot, W. J., Kluzniak, W., Shu, X. O., Gao, Y. T., Schumacher, F., Freedman, M. L., Berchuck, A., Dunning, A. M., Simard, J., Haiman, C. A., Spurdle, A., Sellers, T. A., Hunter, D. J., Henderson, B. E., Kraft, P., Chanock, S. J., Couch, F. J., Hall, P., Gayther, S. A., Easton, D. F., Chenevix-Trench, G., Eeles, R., Pharoah, P. D. P. & Lambrechts, D., Sep 1 2016, In : Cancer Discovery. 6, 9, p. 1052-1067 16 p.

Research output: Contribution to journalArticle

Ovarian Neoplasms
Meta-Analysis
Prostatic Neoplasms
Genome
Breast Neoplasms
17 Citations (Scopus)

Germline mutations in PMS2 and MLH1 in individuals with solitary loss of PMS2 expression in colorectal carcinomas from the colon cancer family registry cohort

Rosty, C., Clendenning, M., Walsh, M. D., Eriksen, S. V., Southey, M. C., Winship, I. M., Macrae, F. A., Boussioutas, A., Poplawski, N. K., Parry, S., Arnold, J., Young, J. P., Casey, G., Haile, R. W., Gallinger, S., Le Marchand, L., Newcomb, P. A., Potter, J. D., Derycke, M., Lindor, N. M. & 6 others, Thibodeau, S. N., Baron, J. A., Win, A. K., Hopper, J. L., Jenkins, M. A. & Buchanan, D. D., 2016, In : BMJ Open. 6, 2, e010293.

Research output: Contribution to journalArticle

Germ-Line Mutation
Colonic Neoplasms
Registries
Colorectal Neoplasms
Mutation
36 Citations (Scopus)

Identification of Susceptibility Loci and Genes for Colorectal Cancer Risk

Zeng, C., Matsuda, K., Jia, W. H., Chang, J., Kweon, S. S., Xiang, Y. B., Shin, A., Jee, S. H., Kim, D. H., Zhang, B., Cai, Q., Guo, X., Long, J., Wang, N., Courtney, R., Pan, Z. Z., Wu, C., Takahashi, A., Shin, M. H., Matsuo, K. & 87 others, Matsuda, F., Gao, Y. T., Oh, J. H., Kim, S., Jung, K. J., Ahn, Y. O., Ren, Z., Li, H. L., Wu, J., Shi, J., Wen, W., Yang, G., Li, B., Ji, B. T., Gruber, S. B., Schumacher, F. R., Stenzel, S. L., Casey, G., Hopper, J. L., Jenkins, M. A., Kim, H. R., Jeong, J. Y., Park, J. W., Tajima, K., Cho, S. H., Kubo, M., Shu, X. O., Lin, D., Zeng, Y. X., Zheng, W., Brenner, H., Schoen, R. E., Küry, S., Baron, J. A., Berndt, S. I., Bezieau, S., Caan, B. J., Carlson, C. S., Chan, A. T., Chang-Claude, J., Chanock, S. J., Conti, D. V., Curtis, K., Duggan, D., Fuchs, C. S., Gallinger, S., Giovannucci, E. L., Haile, R. W., Harrison, T. A., Hayes, R. B., Hoffmeister, M., Hsu, L., Hudson, T. J., Hunter, D. J., Hutter, C. M., Jackson, R. D., Jiao, S., Le Marchand, L., Lemire, M., Lindor, N. M., Ma, J., Newcomb, P. A., Peters, U., Potter, J. D., Qu, C., Seminara, D., Slattery, M. L., Thibodeau, S. N., White, E., Zanke, B. W., Blalock, K., Campbell, P. T., Edlund, C. K., Figueiredo, J., Gauderman, W. J., Gong, J., Green, R. C., Harju, J. F., Jacobs, E. J., Li, L., Lin, Y., Manion, F. J., Moreno, V., Mukherjee, B., Raskin, L., Severi, G. & Thomas, D. C., Jun 1 2016, In : Gastroenterology. 150, 7, p. 1633-1645 13 p.

Research output: Contribution to journalArticle

Colorectal Neoplasms
Genes
Prokaryotic Initiation Factor-3
Eukaryotic Initiation Factor-3
Eukaryotic Initiation Factors
14 Citations (Scopus)

Incorporating functional annotations for fine-mapping causal variants in a bayesian framework using summary statistics

Chen, W., McDonnell, S. K., Thibodeau, S. N., Tillmans, L. S. & Schaid, D. J., Nov 1 2016, In : Genetics. 204, 3, p. 933-958 26 p.

Research output: Contribution to journalArticle

Quantitative Trait Loci
Genome-Wide Association Study
Meta-Analysis
Prostate
Lipids
8 Citations (Scopus)

Multivitamin, calcium and folic acid supplements and the risk of colorectal cancer in Lynch syndrome

Chau, R., Dashti, S. G., Ait Ouakrim, D., Buchanan, D. D., Clendenning, M., Rosty, C., Winship, I. M., Young, J. P., Giles, G. G., Macrae, F. A., Boussioutas, A., Parry, S., Figueiredo, J. C., Levine, A. J., Ahnen, D. J., Casey, G., Haile, R. W., Gallinger, S., Le Marchand, L., Thibodeau, S. N. & 7 others, Lindor, N. M., Newcomb, P. A., Potter, J. D., Baron, J. A., Hopper, J. L., Jenkins, M. A. & Win, A. K., Jun 1 2016, In : International Journal of Epidemiology. 45, 3, p. 940-953 14 p.

Research output: Contribution to journalArticle

Hereditary Nonpolyposis Colorectal Neoplasms
Folic Acid
Colorectal Neoplasms
Calcium
DNA Mismatch Repair
49 Citations (Scopus)

Outcome of Whole Exome Sequencing for Diagnostic Odyssey Cases of an Individualized Medicine Clinic: The Mayo Clinic Experience

Lazaridis, K. N., Schahl, K. A., Cousin, M. A., Babovic-Vuksanovic, D., Riegert-Johnson, D. L., Gavrilova, R. M., McAllister, T. M., Lindor, N. M., Abraham, R. S., Ackerman, M. J., Pichurin, P. N., Deyle, D. R., Gavrilov, D. K., Hand, J. L., Klee, E. W., Stephens, M. C., Wick, M. J., Atkinson, E. J., Linden, D. R., Ferber, M. J. & 19 others, Wieben, E. D., Farrugia, G., Baudhuin, L. M., Beck, S. A., Beek, G. J., Go, R. S., Guthrie, K. J., Hovan, M. J., Hunt, K. S., Kemppainen, J. L., Kruisselbrink, T. M., McCormick, J. B., McLaughlin, B. M., Murphree, M. I., Niewold, T. B., Oglesbee, D., Reed, A., Thibodeau, S. N. & Thorland, E. C., Mar 1 2016, In : Mayo Clinic Proceedings. 91, 3, p. 297-307 11 p.

Research output: Contribution to journalArticle

Exome
Precision Medicine
Inborn Genetic Diseases
Insurance Coverage
Medicaid
56 Citations (Scopus)

PALB2, CHEK2 and ATM rare variants and cancer risk: Data from COGS

KConFab investigators & Australian Ovarian Cancer Study Group, Sep 2 2016, (Accepted/In press) In : Journal of Medical Genetics.

Research output: Contribution to journalArticle

Neoplasms
Breast Neoplasms
Mutation
Ovarian Neoplasms
Case-Control Studies
25 Citations (Scopus)

PMS2 monoallelic mutation carriers: The known unknown

Goodenberger, M. L., Thomas, B. C., Riegert-Johnson, D., Boland, C. R., Plon, S. E., Clendenning, M., Win, A. K., Senter, L., Lipkin, S. M., Stadler, Z. K., Macrae, F. A., Lynch, H. T., Weitzel, J. N., De La Chapelle, A., Syngal, S., Lynch, P., Parry, S., Jenkins, M. A., Gallinger, S., Holter, S. & 10 others, Aronson, M., Newcomb, P. A., Burnett, T., Le Marchand, L., Pichurin, P., Hampel, H., Terdiman, J. P., Lu, K. H., Thibodeau, S. N. & Lindor, N. M., Jan 1 2016, In : Genetics in Medicine. 18, 1, p. 13-19 7 p.

Research output: Contribution to journalArticle

Guidelines
Penetrance
Germ-Line Mutation
Mutation
DNA Mismatch Repair
11 Citations (Scopus)

Polyunsaturated fatty acids and prostate cancer risk: A Mendelian randomisation analysis from the PRACTICAL consortium

Khankari, N. K., Murff, H. J., Zeng, C., Wen, W., Eeles, R. A., Easton, D. F., Kote-Jarai, Z., Al Olama, A. A., Benlloch, S., Muir, K., Giles, G. G., Wiklund, F., Gronberg, H., Haiman, C. A., Schleutker, J., Nordestgaard, BØ. G., Travis, R. C., Donovan, J. L., Pashayan, N., Khaw, K. T. & 14 others, Stanford, J. L., Blot, W. J., Thibodeau, S. N., Maier, C., Kibel, A. S., Cybulski, C., Cannon-Albright, L., Brenner, H., Park, J., Kaneva, R., Batra, J., Teixeira, M. R., Pandha, H. & Zheng, W., Aug 23 2016, In : British Journal of Cancer. 115, 5, p. 624-631 8 p.

Research output: Contribution to journalArticle

Mendelian Randomization Analysis
Unsaturated Fatty Acids
Prostatic Neoplasms
Linolenic Acids
Eicosapentaenoic Acid
3 Citations (Scopus)

Post hoc Analysis for Detecting Individual Rare Variant Risk Associations Using Probit Regression Bayesian Variable Selection Methods in Case-Control Sequencing Studies

Larson, N., McDonnell, S., Albright, L. C., Teerlink, C., Stanford, J., Ostrander, E. A., Isaacs, W. B., Xu, J., Cooney, K. A., Lange, E., Schleutker, J., Carpten, J. D., Powell, I., Bailey-Wilson, J., Cussenot, O., Cancel-Tassin, G., Giles, G., MacInnis, R., Maier, C., Whittemore, A. S. & 12 others, Hsieh, C. L., Wiklund, F., Catolona, W. J., Foulkes, W., Mandal, D., Eeles, R., Kote-Jarai, Z., Ackerman, M. J., Olson, T. M., Klein, C. J., Thibodeau, S. N. & Schaid, D. J., Sep 1 2016, In : Genetic Epidemiology. 40, 6, p. 461-469 9 p.

Research output: Contribution to journalArticle

Case-Control Studies
Gene Frequency
Sample Size
Prostatic Neoplasms
Genome
13 Citations (Scopus)

Pubertal development and prostate cancer risk: Mendelian randomization study in a population-based cohort

The PRACTICAL Consortium, 2016, In : BMC Medicine. 14, 1, 66.

Research output: Contribution to journalArticle

Random Allocation
Prostatic Neoplasms
Population
Puberty
Sexual Maturation
145 Citations (Scopus)

REVEL: An Ensemble Method for Predicting the Pathogenicity of Rare Missense Variants

Ioannidis, N. M., Rothstein, J. H., Pejaver, V., Middha, S., McDonnell, S. K., Baheti, S., Musolf, A., Li, Q., Holzinger, E., Karyadi, D., Cannon-Albright, L. A., Teerlink, C. C., Stanford, J. L., Isaacs, W. B., Xu, J., Cooney, K. A., Lange, E. M., Schleutker, J., Carpten, J. D., Powell, I. J. & 21 others, Cussenot, O., Cancel-Tassin, G., Giles, G. G., MacInnis, R. J., Maier, C., Hsieh, C. L., Wiklund, F., Catalona, W. J., Foulkes, W. D., Mandal, D., Eeles, R. A., Kote-Jarai, Z., Bustamante, C. D., Schaid, D. J., Hastie, T., Ostrander, E. A., Bailey-Wilson, J. E., Radivojac, P., Thibodeau, S. N., Whittemore, A. S. & Sieh, W., Oct 6 2016, In : American Journal of Human Genetics. 99, 4, p. 877-885 9 p.

Research output: Contribution to journalArticle

Exome
Virulence
Area Under Curve
Gene Frequency
ROC Curve
24 Citations (Scopus)

Risk of extracolonic cancers for people with biallelic and monoallelic mutations in MUTYH

Win, A. K., Reece, J. C., Dowty, J. G., Buchanan, D. D., Clendenning, M., Rosty, C., Southey, M. C., Young, J. P., Cleary, S. P., Kim, H., Cotterchio, M., Macrae, F. A., Tucker, K. M., Baron, J. A., Burnett, T., Le Marchand, L., Casey, G., Haile, R. W., Newcomb, P. A., Thibodeau, S. N. & 5 others, Hopper, J. L., Gallinger, S., Winship, I. M., Lindor, N. M. & Jenkins, M. A., Oct 1 2016, In : International Journal of Cancer. 139, 7, p. 1557-1563 7 p.

Research output: Contribution to journalArticle

Mutation
Neoplasms
Confidence Intervals
Endometrial Neoplasms
Urinary Bladder Neoplasms
67 Citations (Scopus)

The histone H3.3K36M mutation reprograms the epigenome of chondroblastomas

Fang, D., Gan, H., Lee, J. H., Han, J., Wang, Z., Riester, S. M., Jin, L., Chen, J., Zhou, H., Wang, J., Zhang, H., Yang, N., Bradley, E., Ho, T. H., Rubin, B. P., Bridge, J. A., Thibodeau, S. N., Ordog, T., Chen, Y., van Wijnen, A. J. & 4 others, Oliveira, A. M., Xu, R. M., Westendorf, J. J. & Zhang, Z., Jun 10 2016, In : Science. 352, 6291, p. 1344-1348 5 p.

Research output: Contribution to journalArticle

Chondroblastoma
Chondrocytes
Histones
Methylation
Mutation
3 Citations (Scopus)

The sangre por salud biobank: Facilitating genetic research in an underrepresented latino community

Shaibi, G., Singh, D., De Filippis, E. A., Hernandez, V., Rosenfeld, B., Otu, E., De Oca, G. M., Levey, S., Radecki Breitkopf, C., Sharp, R. R., Olson, J. E., Cerhan, J. R., Thibodeau, S. N., Winkler, E. & Mandarino, L., Aug 1 2016, In : Public Health Genomics. 19, 4, p. 229-238 10 p.

Research output: Contribution to journalArticle

Genetic Research
Hispanic Americans
Health
Precision Medicine
Prehypertension
12 Citations (Scopus)

Tumor eosinophil infiltration and improved survival of colorectal cancer patients: Iowa Women’s Health Study

Prizment, A. E., Vierkant, R. A., Smyrk, T. C., Tillmans, L. S., Lee, J. J., Sriramarao, P., Nelson, H. H., Lynch, C. F., Thibodeau, S. N., Church, T. R., Cerhan, J. R., Anderson, K. E. & Limburg, P. J., Feb 26 2016, (Accepted/In press) In : Modern Pathology.

Research output: Contribution to journalArticle

Women's Health
Eosinophils
Colorectal Neoplasms
Survival
Neoplasms
2015
24 Citations (Scopus)

Aberrant MEK5/ERK5 signalling contributes to human colon cancer progression via NF-κB activation

Simões, A., Pereira, D. M., Gomes, S. E., Brito, H., Carvalho, T., French, A., Castro, R. E., Steer, C. J., Thibodeau, S. N., Rodrigues, C. M. P. & Borralho, P. M., Apr 9 2015, In : Cell Death and Disease. 6, 4, e1718.

Research output: Contribution to journalArticle

Colonic Neoplasms
Cell Movement
Neoplasms
Cell Cycle
Adenocarcinoma
50 Citations (Scopus)

A large multiethnic genome-wide association study of prostate cancer identifies novel risk variants and substantial ethnic differences

Hoffmann, T. J., Van Den Eeden, S. K., Sakoda, L. C., Jorgenson, E., Habel, L. A., Graff, R. E., Passarelli, M. N., Cario, C. L., Emami, N. C., Chao, C. R., Ghai, N. R., Shan, J., Ranatunga, D. K., Quesenberry, C. P., Aaronson, D., Presti, J., Wang, Z., Berndt, S. I., Chanock, S. J., McDonnell, S. K. & 15 others, French, A. J., Schaid, D. J., Thibodeau, S. N., Li, Q., Freedman, M. L., Penney, K. L., Mucci, L. A., Haiman, C. A., Henderson, B. E., Seminara, D., Kvale, M. N., Kwok, P. Y., Schaefer, C., Risch, N. & Witte, J. S., Aug 1 2015, In : Cancer Discovery. 5, 8, p. 878-891 14 p.

Research output: Contribution to journalArticle

Genome-Wide Association Study
Prostatic Neoplasms
Single Nucleotide Polymorphism
Hispanic Americans
African Americans
26 Citations (Scopus)

A large-scale analysis of genetic variants within putative miRNA binding sites in prostate cancer

PRACTICAL Consortium & Australian Prostate Cancer BioResource, Apr 1 2015, In : Cancer Discovery. 5, 4, p. 368-379 12 p.

Research output: Contribution to journalArticle

MicroRNAs
Prostatic Neoplasms
Binding Sites
Genome-Wide Association Study
Alleles
30 Citations (Scopus)

Analysis of Molecular Markers by Anatomic Tumor Site in Stage III Colon Carcinomas from Adjuvant Chemotherapy Trial NCCTG N0147 (Alliance)

for the Alliance for Clinical Trials in Oncology & Sargent, D. J., Dec 1 2015, In : Clinical Cancer Research. 21, 23, p. 5294-5304 11 p.

Research output: Contribution to journalArticle

Adjuvant Chemotherapy
Tumor Biomarkers
Colon
Carcinoma
Neoplasms
26 Citations (Scopus)

Aspirin, Ibuprofen, and the Risk of Colorectal Cancer in Lynch Syndrome

Ouakrim, D. A., Dashti, S. G., Chau, R., Buchanan, D. D., Clendenning, M., Rosty, C., Winship, I. M., Young, J. P., Giles, G. G., Leggett, B., Macrae, F. A., Ahnen, D. J., Casey, G., Gallinger, S., Haile, R. W., Le Marchand, L., Thibodeau, S. N., Lindor, N. M., Newcomb, P. A., Potter, J. D. & 4 others, Baron, J. A., Hopper, J. L., Jenkins, M. A. & Win, A. K., Sep 1 2015, In : Journal of the National Cancer Institute. 107, 9

Research output: Contribution to journalArticle

Hereditary Nonpolyposis Colorectal Neoplasms
Ibuprofen
DNA Mismatch Repair
Aspirin
Colorectal Neoplasms
29 Citations (Scopus)

Association between body mass index and mortality for colorectal cancer survivors: Overall and by tumor molecular phenotype

Campbell, P. T., Newton, C. C., Newcomb, P. A., Phipps, A. I., Ahnen, D. J., Baron, J. A., Buchanan, D. D., Casey, G., Cleary, S. P., Cotterchio, M., Farris, A. B., Figueiredo, J. C., Gallinger, S., Green, R. C., Haile, R. W., Hopper, J. L., Jenkins, M. A., Le Marchand, L., Makar, K. W., McLaughlin, J. R. & 8 others, Potter, J. D., Renehan, A. G., Sinicrope, F. A., Thibodeau, S. N., Ulrich, C. M., Win, A. K., Lindor, N. M. & Limburg, P. J., Aug 1 2015, In : Cancer Epidemiology Biomarkers and Prevention. 24, 8, p. 1229-1238 10 p.

Research output: Contribution to journalArticle

Microsatellite Instability
Survivors
Colorectal Neoplasms
Body Mass Index
Phenotype
103 Citations (Scopus)

Association of aspirin and NSAID use with risk of colorectal cancer according to genetic variants

Nan, H., Hutter, C. M., Lin, Y., Jacobs, E. J., Ulrich, C. M., White, E., Baron, J. A., Berndt, S. I., Brenner, H., Butterbach, K., Caan, B. J., Campbell, P. T., Carlson, C. S., Casey, G., Chang-Claude, J., Chanock, S. J., Cotterchio, M., Duggan, D., Figueiredo, J. C., Fuchs, C. S. & 33 others, Giovannucci, E. L., Gong, J., Haile, R. W., Harrison, T. A., Hayes, R. B., Hoffmeister, M., Hopper, J. L., Hudson, T. J., Jenkins, M. A., Jiao, S., Lindor, N. M., Lemire, M., Le Marchand, L., Newcomb, P. A., Ogino, S., Pflugeisen, B. M., Potter, J. D., Qu, C., Rosse, S. A., Rudolph, A., Schoen, R. E., Schumacher, F. R., Seminara, D., Slattery, M. L., Thibodeau, S. N., Thomas, F., Thornquist, M., Warnick, G. S., Zanke, B. W., Gauderman, W. J., Peters, U., Hsu, L. & Chan, A. T., Mar 17 2015, In : JAMA - Journal of the American Medical Association. 313, 11, p. 1133-1142 10 p.

Research output: Contribution to journalArticle

Aspirin
Colorectal Neoplasms
Anti-Inflammatory Agents
Pharmaceutical Preparations
Single Nucleotide Polymorphism
8 Citations (Scopus)

Associations between environmental exposures and incident colorectal cancer by ESR2 protein expression level in a population-based cohort of older women

Tillmans, L. S., Vierkant, R. A., Wang, A. H., Samadder, N. J., Lynch, C. F., Anderson, K. E., French, A. J., Haile, R. W., Harnack, L. J., Potter, J. D., Slager, S. L., Smyrk, T. C., Thibodeau, S. N., Cerhan, J. R. & Limburg, P. J., Apr 1 2015, In : Cancer Epidemiology Biomarkers and Prevention. 24, 4, p. 713-719 7 p.

Research output: Contribution to journalArticle

Environmental Exposure
Colorectal Neoplasms
Smoking
Population
Folic Acid
20 Citations (Scopus)

Associations of prostate cancer risk variants with disease aggressiveness: results of the NCI-SPORE Genetics Working Group analysis of 18,343 cases

Helfand, B. T., Roehl, K. A., Cooper, P. R., McGuire, B. B., Fitzgerald, L. M., Cancel-Tassin, G., Cornu, J. N., Bauer, S., Van Blarigan, E. L., Chen, X., Duggan, D., Ostrander, E. A., Gwo-Shu, M., Zhang, Z. F., Chang, S. C., Jeong, S., Fontham, E. T. H., Smith, G., Mohler, J. L., Berndt, S. I. & 25 others, McDonnell, S. K., Kittles, R., Rybicki, B. A., Freedman, M., Kantoff, P. W., Pomerantz, M., Breyer, J. P., Smith, J. R., Rebbeck, T. R., Mercola, D., Isaacs, W. B., Wiklund, F., Cussenot, O., Thibodeau, S. N., Schaid, D. J., Cannon-Albright, L., Cooney, K. A., Chanock, S. J., Stanford, J. L., Chan, J. M., Witte, J., Xu, J., Bensen, J. T., Taylor, J. A. & Catalona, W. J., 2015, In : Human Genetics. 134, 4, p. 439-450 12 p.

Research output: Contribution to journalArticle

Single Nucleotide Polymorphism
Prostatic Neoplasms
African Americans
Neoplasm Grading
Genome-Wide Association Study
14 Citations (Scopus)

Biallelic BRCA2 Mutations Shape the Somatic Mutational Landscape of Aggressive Prostate Tumors

Decker, B., Karyadi, D. M., Davis, B. W., Karlins, E., Tillmans, L. S., Stanford, J. L., Thibodeau, S. N. & Ostrander, E. A., Nov 5 2015, (Accepted/In press) In : American Journal of Human Genetics.

Research output: Contribution to journalArticle

Prostate
Mutation
Prostatic Neoplasms
Neoplasms
Biomarkers

Childhood cancers in families with and without Lynch syndrome

Heath, J. A., Reece, J. C., Buchanan, D. D., Casey, G., Durno, C. A., Gallinger, S., Haile, R. W., Newcomb, P. A., Potter, J. D., Thibodeau, S. N., Le Marchand, L., Lindor, N. M., Hopper, J. L., Jenkins, M. A. & Win, A. K., May 12 2015, In : Familial Cancer. 14, 4, p. 545-551 7 p.

Research output: Contribution to journalArticle

Hereditary Nonpolyposis Colorectal Neoplasms
Neoplasms
DNA Mismatch Repair
Colorectal Neoplasms
Genes
206 Citations (Scopus)

Exosomal miR-1290 and miR-375 as prognostic markers in castration-resistant prostate cancer

Huang, X., Yuan, T., Liang, M., Du, M., Xia, S., Dittmar, R., Wang, D., See, W., Costello, B., Quevedo, F., Tan, W., Nandy, D., Bevan, G. H., Longenbach, S., Sun, Z. D., Lu, Y., Wang, T., Thibodeau, S. N., Boardman, L. A., Kohli, M. & 1 others, Wang, L., Jan 1 2015, In : European Urology. 67, 1, p. 33-41 9 p.

Research output: Contribution to journalArticle

Castration
MicroRNAs
Prostatic Neoplasms
Survival
RNA Sequence Analysis
26 Citations (Scopus)

Female hormonal factors and the risk of endometrial cancer in Lynch syndrome

Dashti, S. G., Chau, R., Ouakrim, D. A., Buchanan, D. D., Clendenning, M., Young, J. P., Winship, I. M., Arnold, J., Ahnen, D. J., Haile, R. W., Casey, G., Gallinger, S., Thibodeau, S. N., Lindor, N. M., Le Marchand, L., Newcomb, P. A., Potter, J. D., Baron, J. A., Hopper, J. L., Jenkins, M. A. & 1 others, Win, A. K., Jul 7 2015, In : JAMA - Journal of the American Medical Association. 314, 1, p. 61-71 11 p.

Research output: Contribution to journalArticle

Hereditary Nonpolyposis Colorectal Neoplasms
Endometrial Neoplasms
DNA Mismatch Repair
Live Birth
Mutation
15 Citations (Scopus)

Genome-wide association study of prostate cancer-specific survival

Szulkin, R., Karlsson, R., Whitington, T., Aly, M., Gronberg, H., Eeles, R. A., Easton, D. F., Kote-Jarai, Z., Al Olama, A. A., Benlloch, S., Muir, K., Giles, G. G., Southey, M. C., Fitzgerald, L. M., Henderson, B. E., Schumacher, F. R., Haiman, C. A., Sipeky, C., Tammela, T. J., Nordestgaard, B. G. & 62 others, Key, T. J., Travis, R. C., Neal, D. E., Donovan, J. L., Hamdy, F. C., Pharoah, P. D. P., Pashayan, N., Khaw, K. T., Stanford, J. L., Thibodeau, S. N., McDonnell, S. K., Schaid, D. J., Maier, C., Vogel, W., Luedeke, M., Herkommer, K., Kibel, A. S., Cybulski, C., Lubinski, J., Kluzniak, W., Cannon-Albright, L., Brenner, H., Herrmann, V., Holleczek, B., Park, J. Y., Sellers, T. A., Lim, H. Y., Slavov, C., Kaneva, R. P., Mitev, V. I., Spurdle, A., Teixeira, M. R., Paulo, P., Maia, S., Pandha, H., Michael, A., Kierzek, A., Batra, J., Clements, J. A., Albanes, D., Andriole, G. L., Berndt, S. I., Chanock, S., Gapstur, S. M., Giovannucci, E. L., Hunter, D. J., Kraft, P., Le Marchand, L., Ma, J., Mondul, A. M., Penney, K. L., Stampfer, M. J., Stevens, V. L., Weinstein, S. J., Trichopoulou, A., Bueno-De-mesquita, B. H., Tjønneland, A., Cox, D. G., Maehle, L., Schleutker, J., Lindstrom, S. & Wiklund, F., Nov 1 2015, In : Cancer Epidemiology Biomarkers and Prevention. 24, 11, p. 1796-1800 5 p.

Research output: Contribution to journalArticle

Genome-Wide Association Study
Prostatic Neoplasms
Survival
Survival Analysis
Cause of Death
21 Citations (Scopus)

Heterogenous MSH6 loss is a result of microsatellite instability within MSH6 and occurs in sporadic and hereditary colorectal and endometrial carcinomas

Graham, R., Kerr, S. E., Butz, M. L., Thibodeau, S. N., Halling, K. C., Smyrk, T. C., Dina, M. A., Waugh, V. M. & Rumilla, K. M., Oct 1 2015, In : American Journal of Surgical Pathology. 39, 10, p. 1370-1376 7 p.

Research output: Contribution to journalArticle

Microsatellite Instability
Endometrial Neoplasms
Colorectal Neoplasms
Hereditary Nonpolyposis Colorectal Neoplasms
DNA Mismatch Repair
6 Citations (Scopus)
Exome
Medical Records
Phenotype
Electronic Health Records
Genetic Association Studies
19 Citations (Scopus)

Identification of a common variant with potential pleiotropic effect on risk of inflammatory bowel disease and colorectal cancer

GECCO & CCFR, Mar 24 2015, In : Carcinogenesis. 36, 9, p. 999-1007 9 p.

Research output: Contribution to journalArticle

Inflammatory Bowel Diseases
Colorectal Neoplasms
Ulcerative Colitis
Single Nucleotide Polymorphism
Microsatellite Instability
26 Citations (Scopus)

Identification of candidate genes for prostate cancer-risk SNPs utilizing a normal prostate tissue eQTL data set

Thibodeau, S. N., French, A. J., McDonnell, S. K., Cheville, J., Middha, S., Tillmans, L., Riska, S., Baheti, S., Larson, M. C., Fogarty, Z., Zhang, Y., Larson, N., Nair, A., O'Brien, D., Wang, L. & Schaid, D. J., Nov 27 2015, In : Nature Communications. 6, 8653.

Research output: Contribution to journalArticle

Genetic Association Studies
genes
Single Nucleotide Polymorphism
Prostate
Prostatic Neoplasms
32 Citations (Scopus)

Mendelian randomization study of body mass index and colorectal cancer risk

Thrift, A. P., Gong, J., Peters, U., Chang-Claude, J., Rudolph, A., Slattery, M. L., Chan, A. T., Locke, A. E., Kahali, B., Justice, A. E., Pers, T. H., Gallinger, S., Hayes, R. B., Baron, J. A., J.caan, B., Ogino, S., Berndt, S. I., Chanock, S. J., Casey, G., Haile, R. W. & 22 others, Du, M., Harrison, T. A., Thornquist, M., Duggan, D. J., Le Marchand, L., Lindor, N. M., Seminara, D., Song, M., Wu, K., Thibodeau, S. N., Cotterchio, M., Win, A. K., Jenkins, M. A., Hopper, J., Ulrich, C. M., Potter, J. D., Newcomb, P. A., Hoffmeister, M., Brenner, H., White, E., Hsu, L. & Campbell, P. T., Jul 1 2015, In : Cancer Epidemiology Biomarkers and Prevention. 24, 7, p. 1024-1031 8 p.

Research output: Contribution to journalArticle

Random Allocation
Colorectal Neoplasms
Body Mass Index
Confidence Intervals
Mendelian Randomization Analysis
30 Citations (Scopus)

Mendelian randomization study of height and risk of colorectal cancer

GIANT Consortium, May 27 2015, In : International Journal of Epidemiology. 44, 2, p. 662-672 11 p., dyv082.

Research output: Contribution to journalArticle

Random Allocation
Colorectal Neoplasms
Odds Ratio
Confidence Intervals
Observational Studies
160 Citations (Scopus)

Molecular markers identify subtypes of stage III colon cancer associated with patient outcomes

Sinicrope, F. A., Shi, Q. D., Smyrk, T. C., Thibodeau, S. N., Dienstmann, R., Guinney, J., Bot, B. M., Tejpar, S., Delorenzi, M., Goldberg, R. M., Mahoney, M., Sargent, D. J. & Alberts, S. R., Jan 1 2015, In : Gastroenterology. 148, 1, p. 88-99 12 p.

Research output: Contribution to journalArticle

DNA Mismatch Repair
Colonic Neoplasms
Mutation
Neoplasms
Disease-Free Survival
39 Citations (Scopus)

Multiple novel prostate cancer susceptibility signals identified by fine-mapping of known risk loci among Europeans

The PRACTICAL Consortium, COGS-CRUK GWAS-ELLIPSE (Part of GAME-ON) Initiative, The Australian Prostate Cancer Bioresource, The UK Genetic Prostate Cancer Study Collaborators & The UK ProtecT Study Collaborators, Oct 1 2015, In : Human Molecular Genetics. 24, 19, p. 5589-5602 14 p., ddv203.

Research output: Contribution to journalArticle

Prostatic Neoplasms
Genome-Wide Association Study
Single Nucleotide Polymorphism
Linkage Disequilibrium
Cell Line
28 Citations (Scopus)

Prediction of individual genetic risk to prostate cancer using a polygenic score

The Australian Prostate Cancer Bioresource & The PRACTICAL Consortium, Sep 1 2015, In : Prostate. 75, 13, p. 1467-1474 8 p.

Research output: Contribution to journalArticle

Prostatic Neoplasms
Area Under Curve
Genetic Markers
Genome
Population
28 Citations (Scopus)

Prostate cancer risk locus at 8q24 as a regulatory hub by physical interactions with multiple genomic loci across the genome

Du, M., Yuan, T., Schilter, K. F., Dittmar, R. L., Mackinnon, A., Huang, X., Tschannen, M., Worthey, E., Jacob, H., Xia, S., Gao, J., Tillmans, L., Lu, Y., Liu, P., Thibodeau, S. N. & Wang, L., Jan 1 2015, In : Human Molecular Genetics. 24, 1, p. 154-166 13 p., ddu426.

Research output: Contribution to journalArticle

Prostatic Neoplasms
Genome
Cell Line
Genes
Chromosomes
35 Citations (Scopus)
Mutation Rate
Colonic Neoplasms
Survival
Neoplasms
Adjuvant Chemotherapy
38 Citations (Scopus)

Risk analysis of prostate cancer in practical, a multinational consortium, using 25 known prostate cancer susceptibility loci

UK Genetic Prostate Cancer Study Collaborators/ British Association of Urological Surgeons' Section of Oncology, UK Protect Study Collaborators, PRACTICAL Consortium, Jul 1 2015, In : Cancer Epidemiology Biomarkers and Prevention. 24, 7, p. 1121-1129 9 p.

Research output: Contribution to journalArticle

Prostatic Neoplasms
Odds Ratio
Genome-Wide Association Study
Single Nucleotide Polymorphism
6 Citations (Scopus)

Risk of colorectal cancer for people with a mutation in both a MUTYH and a DNA mismatch repair gene

Win, A. K., Reece, J. C., Buchanan, D. D., Clendenning, M., Young, J. P., Cleary, S. P., Kim, H., Cotterchio, M., Dowty, J. G., MacInnis, R. J., Tucker, K. M., Winship, I. M., Macrae, F. A., Burnett, T., Le Marchand, L., Casey, G., Haile, R. W., Newcomb, P. A., Thibodeau, S. N., Lindor, N. M. & 3 others, Hopper, J. L., Gallinger, S. & Jenkins, M. A., Jul 23 2015, In : Familial Cancer. 14, 4, p. 575-583 9 p.

Research output: Contribution to journalArticle

DNA Mismatch Repair
Colorectal Neoplasms
Mutation
Genes
Exome