• 45389 Citations
  • 100 Scopus h-Index
1978 …2021
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Research Output 1978 2019

  • 45389 Citations
  • 100 Scopus h-Index
  • 489 Article
  • 4 Chapter
  • 3 Comment/debate
  • 1 Review article
2010
16 Citations (Scopus)

Model-based prediction of defective DNA mismatch repair using clinicopathological variables in sporadic colon cancer patients

Sinicrope, F. A., Foster, N. R., Sargent, D. J., Thibodeau, S. N., Smyrk, T. C. & O'Connell, M. J., Apr 1 2010, In : Cancer. 116, 7, p. 1691-1698 8 p.

Research output: Contribution to journalArticle

DNA Mismatch Repair
Colonic Neoplasms
Tumor-Infiltrating Lymphocytes
Neoplasms
Sex Differentiation
6 Citations (Scopus)

Parent of origin effects on age at colorectal cancer diagnosis

Lindor, N. M., Rabe, K. G., Petersen, G. M., Chen, H., Bapat, B., Hopper, J., Young, J., Jenkins, M., Potter, J., Newcomb, P., Templeton, A., LeMarchand, L., Grove, J., Burgio, M. R., Haile, R., Green, J., Woods, M. O., Seminara, D., Limburg, P. J. & Thibodeau, S. N., Jul 15 2010, In : International Journal of Cancer. 127, 2, p. 361-366 6 p.

Research output: Contribution to journalArticle

Nuclear Family
Colorectal Neoplasms
Fathers
Genomic Imprinting
Organized Financing
154 Citations (Scopus)

Pharmacogenetic predictors of adverse events and response to chemotherapy in metastatic colorectal cancer: Results from North American Gastrointestinal Intergroup Trial N9741

McLeod, H. L., Sargent, D. J., Marsh, S., Green, E. M., King, C. R., Fuchs, C. S., Ramanathan, R. K., Williamson, S. K., Findlay, B. P., Thibodeau, S. N., Grothey, A. F., Morton, R. F. & Goldberg, R. M., Jul 10 2010, In : Journal of Clinical Oncology. 28, 20, p. 3227-3233 7 p.

Research output: Contribution to journalArticle

oxaliplatin
Pharmacogenetics
irinotecan
Colorectal Neoplasms
Drug Therapy
206 Citations (Scopus)

Risks of lynch syndrome cancers for msh6 mutation carriers

Baglietto, L., Lindor, N. M., Dowty, J. G., White, D. M., Wagner, A., Gomez Garcia, E. B., Vriends, A. H. J. T., Cartwright, N. R., Barnetson, R. A., Farrington, S. M., Tenesa, A., Hampel, H., Buchanan, D., Arnold, S., Young, J., Walsh, M. D., Jass, J., MacRae, F., Antill, Y., Winship, I. M. & 19 others, Giles, G. G., Goldblatt, J., Parry, S., Suthers, G., Leggett, B., Butz, M., Aronson, M., Poynter, J. N., Baron, J. A., Le Marchand, L., Haile, R., Gallinger, S., Hopper, J. L., Potter, J., De La Chapelle, A., Vasen, H. F., Dunlop, M. G., Thibodeau, S. N. & Jenkins, M. A., Feb 2010, In : Journal of the National Cancer Institute. 102, 3, p. 193-201 9 p.

Research output: Contribution to journalArticle

Hereditary Nonpolyposis Colorectal Neoplasms
Confidence Intervals
Mutation
Neoplasms
Colorectal Neoplasms
31 Citations (Scopus)

Specific variants in the MLH1 gene region may drive DNA methylation, loss of protein expression, and MSI-H colorectal cancer

Mrkonjic, M., Roslin, N. M., Greenwood, C. M., Raptis, S., Pollett, A., Laird, P. W., Pethe, V. V., Chiang, T., Daftary, D., Dicks, E., Thibodeau, S. N., Gallinger, S., Parfrey, P. S., Younghusband, H. B., Potter, J. D., Hudson, T. J., McLaughlin, J. R., Green, R. C., Zanke, B. W., Newcomb, P. A. & 2 others, Paterson, A. D. & Bapat, B., Oct 13 2010, In : PLoS One. 5, 10, e13314.

Research output: Contribution to journalArticle

DNA methylation
DNA Methylation
colorectal neoplasms
Colorectal Neoplasms
protein synthesis
44 Citations (Scopus)

The genetic basis of colorectal cancer in a population-based incident cohort with a high rate of familial disease

Woods, M. O., Younghusband, H. B., Parfrey, P. S., Gallinger, S., McLaughlin, J., Dicks, E., Stuckless, S., Pollett, A., Bapat, B., Mrkonjic, M., De La Chapelle, A., Clendenning, M., Thibodeau, S. N., Simms, M., Dohey, A., Williams, P., Robb, D., Searle, C., Green, J. S. & Green, R. C., 2010, In : Gut. 59, 10, p. 1369-1377 9 p.

Research output: Contribution to journalArticle

Colorectal Neoplasms
Mutation
Population
Microsatellite Instability
DNA Mismatch Repair
2009
91 Citations (Scopus)

Associations between smoking, alcohol consumption, and colorectal cancer, overall and by tumor microsatellite instability status

Poynter, J. N., Haile, R. W., Siegmund, K. D., Campbell, P. T., Figueiredo, J. C., Limburg, P. J., Young, J., Le Marchand, L., Potter, J. D., Cotterchio, M., Casey, G., Hopper, J. L., Jenkins, M. A., Thibodeau, S. N., Newcomb, P. A. & Baron, J. A., Oct 2009, In : Cancer Epidemiology Biomarkers and Prevention. 18, 10, p. 2745-2750 6 p.

Research output: Contribution to journalArticle

Microsatellite Instability
Alcohol Drinking
Colorectal Neoplasms
Smoking
Neoplasms
246 Citations (Scopus)

A transposon-based genetic screen in mice identifies genes altered in colorectal cancer

Starr, T. K., Allaei, R., Silverstein, K. A. T., Staggs, R. A., Sarver, A. L., Bergemann, T. L., Gupta, M., Gerard O'Sullivan, M., Matise, I., Dupuy, A. J., Collier, L. S., Powers, S., Oberg, A. L., Asmann, Y., Thibodeau, S. N., Tessarollo, L., Copeland, N. G., Jenkins, N. A., Cormier, R. T. & Largaespada, D. A., Mar 27 2009, In : Science. 323, 5922, p. 1747-1750 4 p.

Research output: Contribution to journalArticle

Colorectal Neoplasms
Beauty
Genes
Carcinogenesis
APC Genes
22 Citations (Scopus)

Deficiencies in Chfr and Mlh1 synergistically enhance tumor susceptibility in mice

Fu, Z., Regan, K., Zhang, L., Muders, M. H., Thibodeau, S. N., French, A., Wu, Y., Kaufmann, S. H., Lingle, W. L., Chen, J. & Tindall, D. J., Sep 1 2009, In : Journal of Clinical Investigation. 119, 9, p. 2714-2724 11 p.

Research output: Contribution to journalArticle

Colonic Neoplasms
Carcinogenesis
M Phase Cell Cycle Checkpoints
Microsatellite Instability
DNA Mismatch Repair
318 Citations (Scopus)

EGAPP supplementary evidence review: DNA testing strategies aimed at reducing morbidity and mortality from Lynch syndrome

Palomaki, G. E., McClain, M. R., Melillo, S., Hampel, H. L. & Thibodeau, S. N., Jan 2009, In : Genetics in Medicine. 11, 1, p. 42-65 24 p.

Research output: Contribution to journalArticle

Hereditary Nonpolyposis Colorectal Neoplasms
Centers for Disease Control and Prevention (U.S.)
Genomics
Blue Cross Blue Shield Insurance Plans
Morbidity
14 Citations (Scopus)

Epitope-positive truncating MLH1 mutation and loss of PMS2: Implications for IHC-directed genetic testing for lynch syndrome

Zighelboim, I., Powell, M. A., Babb, S. A., Whelan, A. J., Schmidt, A. P., Clendenning, M., Senter, L., Thibodeau, S. N., De La Chapelle, A. & Goodfellow, P. J., Dec 2009, In : Familial Cancer. 8, 4, p. 501-504 4 p.

Research output: Contribution to journalArticle

Hereditary Nonpolyposis Colorectal Neoplasms
Genetic Testing
Microsatellite Instability
Epitopes
Immunohistochemistry
22 Citations (Scopus)

Evaluation of a new high-dimensional miRNA profiling platform

Cunningham, J. M., Oberg, A. L., Borralho, P. M., Kren, B. T., French, A. J., Wang, L., Bot, B. M., Morlan, B. W., Silverstein, K. A., Staggs, R., Zeng, Y., Lamblin, A. F., Hilker, C. A., Fan, J. B., Steer, C. J. & Thibodeau, S. N., 2009, In : BMC Medical Genomics. 2, 57.

Research output: Contribution to journalArticle

MicroRNAs
RNA
Eukaryota
Colonic Neoplasms
Nucleotides
33 Citations (Scopus)

Functional and clinical significance of variants localized to 8q24 in colon cancer

Cicek, M., Slager, S. L., Achenbach, S. J., French, A. J., Blair, H. E., Fink, S. R., Foster, N. R., Kabat, B. F., Halling, K. C., Cunningham, J. M., Cerhan, J. R., Jenkins, R. B., Boardman, L. A., Petersen, G. M., Sargent, D. J., Alberts, S. R., Limburg, P. J. & Thibodeau, S. N., Sep 2009, In : Cancer Epidemiology Biomarkers and Prevention. 18, 9, p. 2492-2500 9 p.

Research output: Contribution to journalArticle

Chromosome Fragility
Colonic Neoplasms
Fluorescence In Situ Hybridization
Alleles
Odds Ratio
104 Citations (Scopus)

Gene networks and microRNAs implicated in aggressive prostate cancer

Wang, L., Tang, H., Thayanithy, V., Subramanian, S., Oberg, A. L., Cunningham, J. M., Cerhan, J. R., Steer, C. J. & Thibodeau, S. N., Dec 15 2009, In : Cancer Research. 69, 24, p. 9490-9497 8 p.

Research output: Contribution to journalArticle

Gene Regulatory Networks
MicroRNAs
Prostatic Neoplasms
Genes
Phenotype
62 Citations (Scopus)

Genome-wide transcriptional profiling reveals microRNA-correlated genes and biological processes in human lymphoblastoid cell lines

Wang, L., Oberg, A. L., Asmann, Y., Sicotte, H., McDonnell, S. K., Riska, S. M., Liu, W., Steer, C. J., Subramanian, S., Cunningham, J. M., Cerhan, J. R. & Thibodeau, S. N., Jun 11 2009, In : PLoS One. 4, 6, e5878.

Research output: Contribution to journalArticle

Biological Phenomena
human cell lines
MicroRNAs
microRNA
Genes
243 Citations (Scopus)

Human colon cancer profiles show differential microRNA expression depending on mismatch repair status and are characteristic of undifferentiated proliferative states

Sarver, A. L., French, A. J., Borralho, P. M., Thayanithy, V., Oberg, A. L., Silverstein, K. A. T., Morlan, B. W., Riska, S. M., Boardman, L. A., Cunningham, J. M., Subramanian, S., Wang, L., Smyrk, T. C., Rodrigues, C. M. P., Thibodeau, S. N. & Steer, C. J., Nov 18 2009, In : BMC Cancer. 9, 401.

Research output: Contribution to journalArticle

DNA Mismatch Repair
MicroRNAs
Colonic Neoplasms
Neoplasms
Colon
329 Citations (Scopus)

Identification of seven new prostate cancer susceptibility loci through a genome-wide association study

Eeles, R. A., Kote-Jarai, Z., Al Olama, A. A., Giles, G. G., Guy, M., Severi, G., Muir, K., Hopper, J. L., Henderson, B. E., Haiman, C. A., Schleutker, J., Hamdy, F. C., Neal, D. E., Donovan, J. L., Stanford, J. L., Ostrander, E. A., Ingles, S. A., John, E. M., Thibodeau, S. N., Schaid, D. J. & 81 others, Park, J. Y., Spurdle, A., Clements, J., Dickinson, J. L., Maier, C., Vogel, W., Dörk, T., Rebbeck, T. R., Cooney, K. A., Cannon-Albright, L., Chappuis, P. O., Hutter, P., Zeegers, M., Kaneva, R., Zhang, H. W., Lu, Y. J., Foulkes, W. D., English, D. R., Leongamornlert, D. A., Tymrakiewicz, M., Morrison, J., Ardern-Jones, A. T., Hall, A. L., O'Brien, L. T., Wilkinson, R. A., Saunders, E. J., Page, E. C., Sawyer, E. J., Edwards, S. M., Dearnaley, D. P., Horwich, A., Huddart, R. A., Khoo, V. S., Parker, C. C., Van As, N., Woodhouse, C. J., Thompson, A., Christmas, T., Ogden, C., Cooper, C. S., Southey, M. C., Lophatananon, A., Liu, J. F., Kolonel, L. N., Le Marchand, L., Wahlfors, T., Tammela, T. L., Auvinen, A., Lewis, S. J., Cox, A., Fitzgerald, L. M., Koopmeiners, J. S., Karyadi, D. M., Kwon, E. M., Stern, M. C., Corral, R., Joshi, A. D., Shahabi, A., McDonnell, S. K., Sellers, T. A., Pow-Sang, J., Chambers, S., Aitken, J., Gardiner, R. A., Batra, J., Kedda, M. A., Lose, F., Polanowski, A., Patterson, B., Serth, J., Meyer, A., Luedeke, M., Stefflova, K., Ray, A. M., Lange, E. M., Farnham, J., Khan, H., Slavov, C., Mitkova, A., Cao, G. & Easton, D. F., Oct 2009, In : Nature Genetics. 41, 10, p. 1116-1121 6 p.

Research output: Contribution to journalArticle

Genome-Wide Association Study
Prostatic Neoplasms
Single Nucleotide Polymorphism
Chromosomes, Human, Pair 4
Chromosomes, Human, Pair 2
31 Citations (Scopus)

Lymphocyte recruitment into the tumor site is altered in patients with MSI-H colon cancer

Drescher, K. M., Sharma, P., Watson, P., Gatalica, Z., Thibodeau, S. N. & Lynch, H. T., Sep 2009, In : Familial Cancer. 8, 3, p. 231-239 9 p.

Research output: Contribution to journalArticle

Colonic Neoplasms
Lymphocytes
Neoplasms
Colorectal Neoplasms
Peripheral Tolerance
29 Citations (Scopus)

Mutations in the human naked cuticle homolog NKD1 found in colorectal cancer alter Wnt/Dvl/β-catenin signaling

Guo, J., Cagatay, T., Zhou, G., Chan, C. C., Blythe, S., Suyama, K., Zheng, L., Pan, K., Qian, C., Hamelin, R., Thibodeau, S. N., Klein, P. S., Wharton, K. A. & Liu, W., Nov 24 2009, In : PLoS One. 4, 11, e7982.

Research output: Contribution to journalArticle

Catenins
colorectal neoplasms
Colorectal Neoplasms
Genes
mutation
7 Citations (Scopus)

Pediatric duodenal cancer and biallelic mismatch repair gene mutations

Roy, S., Raskin, L., Raymond, V. M., Thibodeau, S. N., Mody, R. J. & Gruber, S. B., Jul 15 2009, In : Pediatric Blood and Cancer. 53, 1, p. 116-120 5 p.

Research output: Contribution to journalArticle

Duodenal Neoplasms
DNA Mismatch Repair
Pediatrics
Intestinal Neoplasms
Mutation
19 Citations (Scopus)

The association of tumor microsatellite instability phenotype with family history of colorectal cancer

Bapat, B., Lindor, N. M., Baron, J., Siegmund, K., Li, L., Zheng, Y., Haile, R., Gallinger, S., Jass, J. R., Young, J. P., Cotterchio, M., Jenkins, M., Grove, J., Casey, G., Thibodeau, S. N., Bishop, D. T., Hopper, J. L., Ahnen, D., Newcomb, P. A., Le Marchand, L. & 2 others, Potter, J. D. & Seminara, D., Mar 2009, In : Cancer Epidemiology Biomarkers and Prevention. 18, 3, p. 967-975 9 p.

Research output: Contribution to journalArticle

Microsatellite Instability
Colorectal Neoplasms
Phenotype
Neoplasms
Guidelines
2008
102 Citations (Scopus)

Alpha1-antitrypsin deficiency carriers, tobacco smoke, chronic obstructive pulmonary disease, and lung cancer risk

Yang, P., Sun, Z. D., Krowka, M. J., Aubry, M. C., Bamlet, W. R., Wampfler, J. A., Thibodeau, S. N., Katzmann, J. A., Allen, M. S., Midthun, D. E., Marks, R. S. & De Andrade, M., May 26 2008, In : Archives of Internal Medicine. 168, 10, p. 1097-1103 7 p.

Research output: Contribution to journalArticle

Smoke
Chronic Obstructive Pulmonary Disease
Tobacco
Lung Neoplasms
Siblings
16 Citations (Scopus)

Altered DNA Mismatch Repair Expression in Synchronous and Metachronous Colorectal Cancers

Aslanian, H. R., Burgart, L. J., Harrington, J. J., Mahoney, D. W., Zinsmeister, A. R., Thibodeau, S. N. & Ahlquist, D. A., Dec 2008, In : Clinical Gastroenterology and Hepatology. 6, 12, p. 1385-1388 4 p.

Research output: Contribution to journalArticle

DNA Mismatch Repair
Colorectal Neoplasms
Hereditary Nonpolyposis Colorectal Neoplasms
Staining and Labeling
Neoplasms
110 Citations (Scopus)

BRAF V600E disrupts AZD6244-induced abrogation of negative feedback pathways between extracellular signal-regulated kinase and Raf proteins

Friday, B. B., Yu, C., Dy, G. K., Smith, P. D., Wang, L., Thibodeau, S. N. & Adjei, A., Aug 1 2008, In : Cancer Research. 68, 15, p. 6145-6153 9 p.

Research output: Contribution to journalArticle

Extracellular Signal-Regulated MAP Kinases
Proteins
Mitogen-Activated Protein Kinase Kinases
Cell Line
Gastrin-Secreting Cells
4 Citations (Scopus)

Clustering of Lynch syndrome malignancies with no evidence for a role of DNA mismatch repair

Case, A. S., Zighelboim, I., Mutch, D. G., Babb, S. A., Schmidt, A. P., Whelan, A. J., Thibodeau, S. N. & Goodfellow, P. J., Feb 2008, In : Gynecologic Oncology. 108, 2, p. 438-444 7 p.

Research output: Contribution to journalArticle

Hereditary Nonpolyposis Colorectal Neoplasms
DNA Mismatch Repair
Cluster Analysis
Neoplasms
Microsatellite Instability
291 Citations (Scopus)

Common sequence variants on 2p15 and Xp11.22 confer susceptibility to prostate cancer

Gudmundsson, J., Sulem, P., Rafnar, T., Bergthorsson, J. T., Manolescu, A., Gudbjartsson, D., Agnarsson, B. A., Sigurdsson, A., Benediktsdottir, K. R., Blondal, T., Jakobsdottir, M., Stacey, S. N., Kostic, J., Kristinsson, K. T., Birgisdottir, B., Ghosh, S., Magnusdottir, D. N., Thorlacius, S., Thorleifsson, G., Zheng, S. L. & 51 others, Sun, J., Chang, B. L., Elmore, J. B., Breyer, J. P., McReynolds, K. M., Bradley, K. M., Yaspan, B. L., Wiklund, F., Stattin, P., Lindström, S., Adami, H. O., McDonnell, S. K., Schaid, D. J., Cunningham, J. M., Wang, L., Cerhan, J. R., St. Sauver, J., Isaacs, S. D., Wiley, K. E., Partin, A. W., Walsh, P. C., Polo, S., Ruiz-Echarri, M., Navarrete, S., Fuertes, F., Saez, B., Godino, J., Weijerman, P. C., Swinkels, D. W., Aben, K. K., Witjes, J. A., Suarez, B. K., Helfand, B. T., Frigge, M. L., Kristjansson, K., Ober, C., Jonsson, E., Einarsson, G. V., Xu, J., Gronberg, H., Smith, J. R., Thibodeau, S. N., Isaacs, W. B., Catalona, W. J., Mayordomo, J. I., Kiemeney, L. A., Barkardottir, R. B., Gulcher, J. R., Thorsteinsdottir, U., Kong, A. & Stefansson, K., Mar 2008, In : Nature Genetics. 40, 3, p. 281-283 3 p.

Research output: Contribution to journalArticle

Prostatic Neoplasms
Genome-Wide Association Study
Single Nucleotide Polymorphism
Odds Ratio
7 Citations (Scopus)

Fine mapping of familial prostate cancer families narrows the interval for a susceptibility locus on chromosome 22q12.3 to 1.36 Mb

Johanneson, B., McDonnell, S. K., Karyadi, D. M., Hebbring, S. J., Wang, L., Deutsch, K., McIntosh, L., Kwon, E. M., Suuriniemi, M., Stanford, J. L., Schaid, D. J., Ostrander, E. A. & Thibodeau, S. N., Feb 2008, In : Human Genetics. 123, 1, p. 65-75 11 p.

Research output: Contribution to journalArticle

Chromosomes
Prostatic Neoplasms
Genetic Recombination
Consensus
Genetic Research
106 Citations (Scopus)

MGMT immunohistochemical expression and promoter methylation in human glioblastoma

Rodriguez, F. J., Thibodeau, S. N., Jenkins, R. B., Schowalter, K. V., Caron, B. L., O'Neill, B. P., David James, C., Passe, S., Slezak, J. & Giannini, C., Jan 2008, In : Applied Immunohistochemistry and Molecular Morphology. 16, 1, p. 59-65 7 p.

Research output: Contribution to journalArticle

Methyltransferases
Glioblastoma
Methylation
DNA
Immunohistochemistry

MGMT immunohistochemical expression and promoter methylation in human glioblastoma (Applied Immunohistochemistry and Molecular Morphology (2008) 16, (59-65))

Rodriguez, F. J., Thibodeau, S. N., Jenkins, R. B., Schowalter, K. V., Caron, B. L., O'Neill, B. P., David James, C., Passe, S., Slezak, J. & Giannini, C., May 2008, In : Applied Immunohistochemistry and Molecular Morphology. 16, 3, p. 307 1 p.

Research output: Contribution to journalArticle

Glioblastoma
Methylation
Immunohistochemistry
136 Citations (Scopus)

Molecular characterization of MSI-H colorectal cancer by MLHI promoter methylation, immunohistochemistry, and mismatch repair germline mutation screening

Poynter, J. N., Siegmund, K. D., Weisenberger, D. J., Long, T. I., Thibodeau, S. N., Lindor, N. M., Young, J., Jenkins, M. A., Hopper, J. L., Baron, J. A., Buchanan, D., Casey, G., Levine, A. J., Le Marchand, L., Gallinger, S., Bapat, B., Potter, J. D., Newcomb, P. A., Haile, R. W. & Laird, P. W., Nov 2008, In : Cancer Epidemiology Biomarkers and Prevention. 17, 11, p. 3208-3215 8 p.

Research output: Contribution to journalArticle

Microsatellite Instability
DNA Mismatch Repair
Germ-Line Mutation
Methylation
Colorectal Neoplasms
121 Citations (Scopus)

Multiple novel prostate cancer predisposition loci confirmed by an international study: The PRACTICAL consortium

Kote-Jarai, Z., Easton, D. F., Stanford, J. L., Ostrander, E. A., Schleutker, J., Ingles, S. A., Schaid, D. J., Thibodeau, S. N., Dörk, T., Neal, D., Cox, A., Maier, C., Vogel, W., Guy, M., Muir, K., Lophatananon, A., Kedda, M. A., Spurdle, A., Steginga, S., John, E. M. & 31 others, Giles, G., Hopper, J., Chappuis, P. O., Hutter, P., Foulkes, W. D., Hamel, N., Salinas, C. A., Koopmeiners, J. S., Karyadi, D. M., Johanneson, B., Wahlfors, T., Tammela, T. L., Stern, M. C., Corral, R., McDonnell, S. K., Schürmann, P., Meyer, A., Kuefer, R., Leongamornlert, D. A., Tymrakiewicz, M., Liu, J. F., O'Mara, T., Gardiner, R. A., Aitken, J., Joshi, A. D., Severi, G., English, D. R., Southey, M., Edwards, S. M., Al Olama, A. A. & Eeles, R. A., Aug 2008, In : Cancer Epidemiology Biomarkers and Prevention. 17, 8, p. 2052-2061 10 p.

Research output: Contribution to journalArticle

Prostatic Neoplasms
Single Nucleotide Polymorphism
Odds Ratio
Confidence Intervals
Chromosomes, Human, Pair 6
29 Citations (Scopus)

Mutational analysis of thirty-two double-strand DNA break repair genes in breast and pancreatic cancers

Wang, X., Szabo, C., Qian, C., Amadio, P. G., Thibodeau, S. N., Cerhan, J. R., Petersen, G. M., Liu, W. & Couch, F. J., Feb 15 2008, In : Cancer Research. 68, 4, p. 971-975 5 p.

Research output: Contribution to journalArticle

Double-Stranded DNA Breaks
Pancreatic Neoplasms
DNA Repair
Breast Neoplasms
Genes
31 Citations (Scopus)

Origins and prevalence of the American Founder Mutation of MSH2

Clendenning, M., Baze, M. E., Sun, S., Walsh, K., Liyanarachchi, S., Fix, D., Schunemann, V., Comeras, I., Deacon, M., Lynch, J. F., Gong, G., Thomas, B. C., Thibodeau, S. N., Lynch, H. T., Hampel, H. & De La Chapelle, A., Apr 1 2008, In : Cancer Research. 68, 7, p. 2145-2153 9 p.

Research output: Contribution to journalArticle

Mutation
Hereditary Nonpolyposis Colorectal Neoplasms
DNA Mismatch Repair
North American Indians
Sequence Deletion
41 Citations (Scopus)

Polymorphisms in mitochondrial genes and prostate cancer risk

Wang, L., McDonnell, S. K., Hebbring, S. J., Cunningham, J. M., St. Sauver, J., Cerhan, J. R., Isaya, G., Schaid, D. J. & Thibodeau, S. N., Dec 2008, In : Cancer Epidemiology Biomarkers and Prevention. 17, 12, p. 3558-3566 9 p.

Research output: Contribution to journalArticle

Mitochondrial Genes
Single Nucleotide Polymorphism
Prostatic Neoplasms
Genetic Predisposition to Disease
Genetic Markers
11 Citations (Scopus)

Premutations in the FMR1 gene are uncommon in men undergoing genetic testing for spinocerebellar ataxia

Adams, S. A., Steenblock, K. J., Thibodeau, S. N. & Lindor, N. M., Mar 2008, In : Journal of Neurogenetics. 22, 1, p. 77-92 16 p.

Research output: Contribution to journalArticle

Spinocerebellar Ataxias
Genetic Testing
Ataxia
Genes
Gait Ataxia
31 Citations (Scopus)

Proapoptotic Bad and Bid protein expression predict survival in stages II and III colon cancers

Sinicrope, F. A., Rego, R. L., Foster, N. R., Thibodeau, S. N., Alberts, S. R., Windschitl, H. E. & Sargent, D. J., Jul 1 2008, In : Clinical Cancer Research. 14, 13, p. 4128-4133 6 p.

Research output: Contribution to journalArticle

BH3 Interacting Domain Death Agonist Protein
bcl-Associated Death Protein
Colonic Neoplasms
Survival
Survival Rate
166 Citations (Scopus)

Prognostic significance of defective mismatch repair and BRAF V600E in patients with colon cancer

French, A. J., Sargent, D. J., Burgart, L. J., Foster, N. R., Kabat, B. F., Goldberg, R., Shepherd, L., Windschitl, H. E. & Thibodeau, S. N., Jun 1 2008, In : Clinical Cancer Research. 14, 11, p. 3408-3415 8 p.

Research output: Contribution to journalArticle

DNA Mismatch Repair
Colonic Neoplasms
Neoplasms
Survival
Hereditary Nonpolyposis Colorectal Neoplasms
1 Citation (Scopus)

Prolactinoma as the first manifestation of Gardner's syndrome

Goodin, G. S., McCarville, M. B., Thibodeau, S. N., Skapek, S. X., Khoury, J. D. & Spunt, S. L., Feb 2008, In : Pediatric Blood and Cancer. 50, 2, p. 409-412 4 p.

Research output: Contribution to journalArticle

Gardner Syndrome
Prolactinoma
Adenomatous Polyposis Coli
Brain Neoplasms
APC Genes
56 Citations (Scopus)

Salivary gland-type lung carcinomas: An EGFR immunohistochemical, molecular genetic, and mutational analysis study

Macarenco, R. S., Uphoff, T. S., Gilmer, H. F., Jenkins, R. B., Thibodeau, S. N., Lewis, J. E., Molina, J. R., Yang, P. & Aubry, M. C., Sep 2008, In : Modern Pathology. 21, 9, p. 1168-1175 8 p.

Research output: Contribution to journalArticle

erbB-1 Genes
Mucoepidermoid Carcinoma
Salivary Glands
Adenoid Cystic Carcinoma
Molecular Biology

Searching for epistasis and linkage heterogeneity by correlations of pedigree-specific linkage scores

Schaid, D. J., McDonnell, S. K., Carlson, E. E., Thibodeau, S. N., Stanford, J. L. & Ostrander, E. A., Jul 2008, In : Genetic Epidemiology. 32, 5, p. 464-475 12 p.

Research output: Contribution to journalArticle

Pedigree
Genetic Linkage
Genes
Prostatic Neoplasms
Chromosomes
344 Citations (Scopus)

The Clinical Phenotype of Lynch Syndrome Due to Germ-Line PMS2 Mutations

Senter, L., Clendenning, M., Sotamaa, K., Hampel, H., Green, J., Potter, J. D., Lindblom, A., Lagerstedt, K., Thibodeau, S. N., Lindor, N. M., Young, J., Winship, I., Dowty, J. G., White, D. M., Hopper, J. L., Baglietto, L., Jenkins, M. A. & de la Chapelle, A., Aug 2008, In : Gastroenterology. 135, 2

Research output: Contribution to journalArticle

Hereditary Nonpolyposis Colorectal Neoplasms
Germ-Line Mutation
Phenotype
Mutation
Penetrance
33 Citations (Scopus)

The JNK inhibitor SP600129 enhances apoptosis of HCC cells induced by the tumor suppressor WWOX

Aderca, I., Moser, C. D., Veerasamy, M., Bani-Hani, A. H., Bonilla-Guerrero, R., Ahmed, K., Shire, A., Cazanave, S. C., Montoya, D. P., Mettler, T. A., Burgart, L. J., Nagorney, D. M., Thibodeau, S. N., Cunningham, J. M., Lai, J. P. & Roberts, L. R., Sep 2008, In : Journal of Hepatology. 49, 3, p. 373-383 11 p.

Research output: Contribution to journalArticle

Hepatocellular Carcinoma
Apoptosis
Neoplasms
Chromosomes, Human, Pair 16
Messenger RNA
2007
2 Citations (Scopus)

Affected relative pairs and simultaneous search for two-locus linkage in the presence of epistasis

Schaid, D. J., McDonnell, S. K., Carlson, E. E., Thibodeau, S. N., Ostrander, E. A. & Stanford, J. L., Jul 2007, In : Genetic Epidemiology. 31, 5, p. 431-449 19 p.

Research output: Contribution to journalArticle

Genetic Linkage
Disease Susceptibility
Lod Score
Chromosomes, Human, Pair 1
Medical Genetics
25 Citations (Scopus)

Alterations in cell proliferation and apoptosis in colon cancers with microsatellite instability

Sinicrope, F. A., Rego, R. L., Garrity-Park, M. M., Foster, N. R., Sargent, D. J., Goldberg, R. M., Wiesenfeld, M., Witzig, T. E., Thibodeau, S. N. & Burgart, L. J., Mar 15 2007, In : International Journal of Cancer. 120, 6, p. 1232-1238 7 p.

Research output: Contribution to journalArticle

Microsatellite Instability
Tumor-Infiltrating Lymphocytes
Colonic Neoplasms
Cell Proliferation
Apoptosis
245 Citations (Scopus)

Colon cancer family registry: An international resource for studies of the genetic epidemiology of colon cancer

Newcomb, P. A., Baron, J., Cotterchio, M., Gallinger, S., Grove, J., Haile, R., Hall, D., Hopper, J. L., Jass, J., Le Marchand, L., Limburg, P. J., Lindor, N. M., Potter, J. D., Templeton, A. S., Thibodeau, S. N. & Seminara, D., Nov 1 2007, In : Cancer Epidemiology Biomarkers and Prevention. 16, 11, p. 2331-2343 13 p.

Research output: Contribution to journalArticle

Molecular Epidemiology
Colonic Neoplasms
Registries
Colorectal Neoplasms
Microsatellite Instability
24 Citations (Scopus)

Compelling evidence for a prostate cancer gene at 22q12.3 by the international consortium for prostate cancer genetics

Camp, N. J., Cannon-Albright, L. A., Farnham, J. M., Baffoe-Bonnie, A. B., George, A., Powell, I., Bailey-Wilson, J. E., Carpten, J. D., Giles, G. G., Hopper, J. L., Severi, G., English, D. R., Foulkes, W. D., Maehle, L., Moller, P., Eeles, R., Easton, D., Badzioch, M. D., Whittemore, A. S., Oakley-Girvan, I. & 25 others, Hsieh, C. L., Dimitrov, L., Xu, J., Stanford, J. L., Johanneson, B., Deutsch, K., McIntosh, L., Ostrander, E. A., Wiley, K. E., Isaacs, S. D., Walsh, P. C., Thibodeau, S. N., McDonnell, S. K., Hebbring, S., Schaid, D. J., Lange, E. M., Cooney, K. A., Tammela, T. L. J., Schleutker, J., Paiss, T., Maier, C., Grönberg, H., Wiklund, F., Emanuelsson, M. & Isaacs, W. B., Jun 2007, In : Human Molecular Genetics. 16, 11, p. 1271-1278 8 p.

Research output: Contribution to journalArticle

Neoplasm Genes
Pedigree
Prostatic Neoplasms
Chromosomes
Genes

Erratum: Diagnosis of α-1-antitrypsin deficiency: An algorithm of genotyping, phenotyping, and quantitation (Clinical Chemistry (2006) 52, (2236-2242) DOI: 10.1373/clinchem.2006.072991)

Snyder, M. R., Katzmann, J. A., Butz, M. L., Wiley, C., Yang, P., Dawson, D. B., Halling, K. C., Highsmith, W. E. J. & Thibodeau, S. N., Sep 2007, In : Clinical Chemistry. 53, 9, p. 1724 1 p.

Research output: Contribution to journalArticle

alpha 1-Antitrypsin
Clinical Chemistry
98 Citations (Scopus)

Estrogen plus progestin use, microsatellite instability, and the risk of colorectal cancer in women

Newcomb, P. A., Zheng, Y., Chia, V. M., Morimoto, L. M., Doria-Rose, V. P., Templeton, A., Thibodeau, S. N. & Potter, J. D., Aug 1 2007, In : Cancer Research. 67, 15, p. 7534-7539 6 p.

Research output: Contribution to journalArticle

Microsatellite Instability
Progestins
Colorectal Neoplasms
Estrogens
Hormones
90 Citations (Scopus)

Evaluation of genetic variations in the androgen and estrogen metabolic pathways as risk factors for sporadic and familial prostate cancer

Cunningham, J. M., Hebbring, S. J., McDonnell, S. K., Cicek, M., Christensen, G. B., Wang, L., Jacobsen, S. J., Cerhan, J. R., Blute, M. L., Schaid, D. J. & Thibodeau, S. N., May 2007, In : Cancer Epidemiology Biomarkers and Prevention. 16, 5, p. 969-978 10 p.

Research output: Contribution to journalArticle

Metabolic Networks and Pathways
Androgens
Prostatic Neoplasms
Estrogens
Cytochrome P-450 CYP1A1
8 Citations (Scopus)

Frequency of defective DNA mismatch repair in colorectal cancer among the Alaska Native people

Boardman, L. A., Lanier, A. P., French, A. J., Schowalter, K. V., Burgart, L. J., Koller, K. R., McDonnell, S. K., Schaid, D. J. & Thibodeau, S. N., Nov 1 2007, In : Cancer Epidemiology Biomarkers and Prevention. 16, 11, p. 2344-2350 7 p.

Research output: Contribution to journalArticle

Inuits
DNA Mismatch Repair
Colorectal Neoplasms
Neoplasms
Microsatellite Instability