Panagiotis Z Anastasiadis, PhD

Professor

  • 4048 Citations
  • 28 h-Index
1990 …2018
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  • 2 Similar Profiles
Cadherins Medicine & Life Sciences
rho GTP-Binding Proteins Medicine & Life Sciences
Adherens Junctions Medicine & Life Sciences
PC12 Cells Medicine & Life Sciences
Neoplasms Medicine & Life Sciences
Cell Movement Medicine & Life Sciences
Rho Guanine Nucleotide Exchange Factors Medicine & Life Sciences
Phosphorylation Chemical Compounds

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Projects 2004 2016

Glioblastoma
src-Family Kinases
Phosphatidylinositol 3-Kinases
Vascular Endothelial Growth Factor A
Therapeutics

Role of the polarity RhoGEF PLEKHG5 on brain tumor dispersal

Anastasiadis, P. Z.

National Institutes of Health

4/1/103/31/13

Project: Research projectExploratory/Developmental Grants

Rho Guanine Nucleotide Exchange Factors
Brain Neoplasms
Glioma
Cell Movement
Cell Polarity

Mayo SPORE in Brain Cancer

Loftus, J. C., Anastasiadis, P. Z., Galanis, E., Buckner, J. C., Sarkaria, J. N., Giannini, C., Ballman, K. V., Yang, P., James, C. D., O'Neill, B. P. P., O'Neill, B. P., Uhm, J., O'Neill, B. P. & Uhm, J.

National Institutes of Health

9/20/048/31/16

Project: Research projectSpecialized Center

Glioma
Brain Neoplasms
Glioblastoma
Measles virus
Research
Cadherins
Kinesin
rho GTP-Binding Proteins
Cell Movement
Contact Inhibition

Research Output 1990 2018

  • 4048 Citations
  • 28 h-Index
  • 62 Article
  • 2 Chapter
  • 2 Review article
  • 1 Comment/debate

Close encounters of the RNAi kind: the silencing life of the adherens junctions

Kourtidis, A. & Anastasiadis, P. Z., Oct 1 2018, In : Current Opinion in Cell Biology. 54, p. 30-36 7 p.

Research output: Contribution to journalReview article

Adherens Junctions
RNA Interference
Disease Progression
Epithelium

Efficacy of the MDM2 inhibitor SAR405838 in glioblastoma is limited by poor distribution across the blood–brain barrier

Kim, M., Ma, D. J., Calligaris, D., Zhang, S., Feathers, R. W., Vaubel, R. A., Meaux, I., Mladek, A. C., Parrish, K. E., Jin, F., Barriere, C., Debussche, L., Watters, J., Tian, S., Decker, P. A., Eckel-Passow, J. E., Kitange, G. J., Johnson, A. J., Parney, I. F., Anastasiadis, P. Z. & 3 othersAgar, N. Y. R., Elmquist, W. F. & Sarkaria, J. N., Sep 1 2018, In : Molecular Cancer Therapeutics. 17, 9, p. 1893-1901 9 p.

Research output: Contribution to journalArticle

Glioblastoma
Blood-Brain Barrier
Heterografts
Pharmaceutical Preparations
Gadolinium
2 Citations

Novel targeted therapy strategies for biliary tract cancers and hepatocellular carcinoma

Deleon, T. T., Ahn, D., Bogenberger, J. M., Anastasiadis, P. Z., Arora, M., Ramanathan, R. K., Aqel, B. A., Vasmatzis, G., Truty, M., Oklu, R., Bekaii-Saab, T. & Borad, M. J., Mar 1 2018, In : Future Oncology. 14, 6, p. 553-566 14 p.

Research output: Contribution to journalReview article

Biliary Tract Neoplasms
Hepatocellular Carcinoma
Neoplasms
Biomarkers
Therapeutics

Simultaneous E-cadherin and PLEKHA7 expression negatively affects E-cadherin/EGFR mediated ovarian cancer cell growth

Rea, K., Roggiani, F., De Cecco, L., Raspagliesi, F., Carcangiu, M. L., Nair-Menon, J., Bagnoli, M., Bortolomai, I., Mezzanzanica, D., Canevari, S., Kourtidis, A., Anastasiadis, P. Z. & Tomassetti, A., Jul 11 2018, In : Journal of Experimental and Clinical Cancer Research. 37, 1, 146.

Research output: Contribution to journalArticle

Cadherins
Ovarian Neoplasms
Growth
Cisplatin
Neoplasms
22 Citations

A central role for cadherin signaling in cancer

Kourtidis, A., Lu, R., Pence, L. J. & Anastasiadis, P. Z., Feb 13 2017, (Accepted/In press) In : Experimental Cell Research.

Research output: Contribution to journalArticle

Cadherins
Adherens Junctions
Cell Adhesion
Neoplasms
Homeostasis