Panagiotis Z Anastasiadis, PhD

  • 4303 Citations
  • 30 Scopus h-Index
1990 …2019
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Research Output 1990 2019

  • 4303 Citations
  • 30 Scopus h-Index
  • 63 Article
  • 2 Chapter
  • 2 Review article
  • 1 Comment/debate
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Article
2019

A phase 1 and randomized, placebo-controlled phase 2 trial of bevacizumab plus dasatinib in patients with recurrent glioblastoma: Alliance/North Central Cancer Treatment Group N0872

Galanis, E., Anderson, S. K., Twohy, E. L., Carrero, X. W., Dixon, J. G., Tran, D. D., Jeyapalan, S. A., Anderson, D. M., Kaufmann, T. J., Feathers, R. W., Giannini, C., Buckner, J. C., Anastasiadis, P. Z. & Schiff, D., Jan 1 2019, In : Cancer.

Research output: Contribution to journalArticle

Glioblastoma
Placebos
Neoplasms
Therapeutics
National Cancer Institute (U.S.)
2018
3 Citations (Scopus)

Efficacy of the MDM2 inhibitor SAR405838 in glioblastoma is limited by poor distribution across the blood–brain barrier

Kim, M., Ma, D. J., Calligaris, D., Zhang, S., Feathers, R. W., Vaubel, R. A., Meaux, I., Mladek, A. C., Parrish, K. E., Jin, F., Barriere, C., Debussche, L., Watters, J., Tian, S., Decker, P. A., Eckel-Passow, J. E., Kitange, G. J., Johnson, A. J., Parney, I. F., Anastasiadis, P. Z. & 3 others, Agar, N. Y. R., Elmquist, W. F. & Sarkaria, J. N., Sep 1 2018, In : Molecular Cancer Therapeutics. 17, 9, p. 1893-1901 9 p.

Research output: Contribution to journalArticle

Glioblastoma
Heterografts
Pharmaceutical Preparations
Gadolinium
Precision Medicine
2 Citations (Scopus)

Simultaneous E-cadherin and PLEKHA7 expression negatively affects E-cadherin/EGFR mediated ovarian cancer cell growth

Rea, K., Roggiani, F., De Cecco, L., Raspagliesi, F., Carcangiu, M. L., Nair-Menon, J., Bagnoli, M., Bortolomai, I., Mezzanzanica, D., Canevari, S., Kourtidis, A., Anastasiadis, P. Z. & Tomassetti, A., Jul 11 2018, In : Journal of Experimental and Clinical Cancer Research. 37, 1, 146.

Research output: Contribution to journalArticle

Cadherins
Ovarian Neoplasms
Growth
Cisplatin
Neoplasms
2017
46 Citations (Scopus)

A central role for cadherin signaling in cancer

Kourtidis, A., Lu, R., Pence, L. J. & Anastasiadis, P. Z., Feb 13 2017, (Accepted/In press) In : Experimental Cell Research.

Research output: Contribution to journalArticle

Cadherins
Adherens Junctions
Cell Adhesion
Neoplasms
Homeostasis
8 Citations (Scopus)

Cadherin complexes recruit mRNAs and RISC to regulate epithelial cell signaling

Kourtidis, A., Necela, B., Lin, W. H., Lu, R., Feathers, R. W., Asmann, Y., Thompson, E. A. & Anastasiadis, P. Z., Oct 1 2017, In : Journal of Cell Biology. 216, 10, p. 3073-3085 13 p.

Research output: Contribution to journalArticle

RNA-Induced Silencing Complex
Adherens Junctions
Cadherins
Epithelial Cells
Messenger RNA
2016
11 Citations (Scopus)

Assessment of tumor heterogeneity, as evidenced by gene expression profiles, pathway activation, and gene copy number, in patients with multifocal invasive lobular breast tumors

Norton, N., Advani, P. P., Serie, D. J., Geiger, X. J., Necela, B. M., Axenfeld, B. C., Kachergus, J. M., Feathers, R. W., Carr, J. M., Crook, J., Moreno Aspitia, A., Anastasiadis, P. Z., Perez, E. A. & Thompson, E. A., Apr 1 2016, In : PLoS One. 11, 4, e0153411.

Research output: Contribution to journalArticle

Lobular Carcinoma
gene dosage
Gene Dosage
Transcriptome
Gene expression
5 Citations (Scopus)

Bringing together cell-to-cell adhesion and miRNA biology in cancer research

Kourtidis, A. & Anastasiadis, P. Z., May 1 2016, In : Future Oncology. 12, 10, p. 1211-1214 4 p.

Research output: Contribution to journalArticle

7 Citations (Scopus)

PLEKHA7 defines an apical junctional complex with cytoskeletal associations and miRNA-mediated growth implications

Kourtidis, A. & Anastasiadis, P. Z., Feb 16 2016, In : Cell Cycle. 15, 4, p. 498-505 8 p.

Research output: Contribution to journalArticle

Adherens Junctions
MicroRNAs
Actin Depolymerizing Factors
Growth
Actins
22 Citations (Scopus)

The cystic fibrosis transmembrane conductance regulator controls biliary epithelial inflammation and permeability by regulating Src tyrosine kinase activity

Fiorotto, R., Villani, A., Kourtidis, A., Scirpo, R., Amenduni, M., Geibel, P. J., Cadamuro, M., Spirli, C., Anastasiadis, P. Z. & Strazzabosco, M., Dec 1 2016, In : Hepatology. 64, 6, p. 2118-2134 17 p.

Research output: Contribution to journalArticle

Cystic Fibrosis Transmembrane Conductance Regulator
src-Family Kinases
Cystic Fibrosis
Toll-Like Receptor 4
Permeability
2015
49 Citations (Scopus)

Distinct E-cadherin-based complexes regulate cell behaviour through miRNA processing or Src and p120 catenin activity

Kourtidis, A., Ngok, S. P., Pulimeno, P., Feathers, R. W., Carpio, L. R., Baker, T. R., Carr, J. M., Yan, I. K., Borges, S., Perez, E. A., Storz, P., Copland, J. A. III., Patel, T. C., Thompson, E. A., Citi, S. & Anastasiadis, P. Z., Sep 1 2015, In : Nature. 17, 9, p. 1145-1157 13 p.

Research output: Contribution to journalArticle

Microcomputers
Cadherins
MicroRNAs
Adherens Junctions
Growth
8 Citations (Scopus)

Expression of polarity genes in human cancer

Lin, W. H., Asmann, Y. & Anastasiadis, P. Z., Mar 30 2015, In : Cancer Informatics. 14, p. 15-28 14 p.

Research output: Contribution to journalArticle

Gene Expression
Neoplasms
Transcriptome
Proteins
Genomics
6 Citations (Scopus)

Pro-tumorigenic phosphorylation of p120 catenin in renal and breast cancer

Kourtidis, A., Yanagisawa, M., Huveldt, D., Copland, J. A. III. & Anastasiadis, P. Z., Jun 11 2015, In : PLoS One. 10, 6, e0129964.

Research output: Contribution to journalArticle

kidney neoplasms
Phosphorylation
Kidney Neoplasms
breast neoplasms
phosphorylation
17 Citations (Scopus)

Src family kinases differentially influence glioma growth and motility

Lewis-Tuffin, L. J., Feathers, R., Hari, P., Durand, N., Li, Z., Rodriguez, F. J., Bakken, K., Carlson, B., Schroeder, M., Sarkaria, J. N. & Anastasiadis, P. Z., Nov 1 2015, In : Molecular Oncology. 9, 9, p. 1783-1798 16 p.

Research output: Contribution to journalArticle

src-Family Kinases
Glioma
Growth
Heterografts
Neoplasms
2014
24 Citations (Scopus)

Cadherin-11 in poor prognosis malignancies and rheumatoid arthritis: Common target, common therapies

Assefnia, S., Dakshanamurthy, S., Auvil, J. M. G., Hampel, C., Anastasiadis, P. Z., Kallakury, B., Uren, A., Foley, D. W., Brown, M. L., Shapiro, L., Brenner, M., Haigh, D. & Byers, S. W., 2014, In : Oncotarget. 5, 6, p. 1458-1474 17 p.

Research output: Contribution to journalArticle

Rheumatoid Arthritis
Neoplasms
Breast Neoplasms
Therapeutics
Celecoxib
21 Citations (Scopus)

Establishment of epithelial polarity - GEF who's minding the GAP?

Ngok, S. P., Lin, W. H. & Anastasiadis, P. Z., 2014, In : Journal of Cell Science. 127, 15, p. 3205-3215 11 p.

Research output: Contribution to journalArticle

GTPase-Activating Proteins
Guanine Nucleotide Exchange Factors
rho GTP-Binding Proteins
Epithelial Cells
GTP Phosphohydrolases
43 Citations (Scopus)

Neuronal pentraxin 2 supports clear cell renal cell carcinoma by activating the AMPA-selective glutamate receptor-4

Von Roemeling, C. A., Radisky, D. C., Marlow, L. A., Cooper, S. J., Grebe, S. K., Anastasiadis, P. Z., Tun, H. W. & Copland, J. A. III., Sep 1 2014, In : Cancer Research. 74, 17, p. 4796-4810 15 p.

Research output: Contribution to journalArticle

alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid
Glutamate Receptors
Renal Cell Carcinoma
Cell Movement
Neoplasms
9 Citations (Scopus)

PTP-PEST targets a novel tyrosine site in p120 catenin to control epithelial cell motility and Rho GTPase activity

Espejo, R., Jeng, Y., Paulucci-Holthauzen, A., Rengifo-Cam, W., Honkus, K., Anastasiadis, P. Z. & Sastry, S. K., Feb 1 2014, In : Journal of Cell Science. 127, 3, p. 497-508 12 p.

Research output: Contribution to journalArticle

Non-Receptor Type 12 Protein Tyrosine Phosphatase
rho GTP-Binding Proteins
Cell Movement
Tyrosine
Epithelial Cells
2013
44 Citations (Scopus)

Pharmacologic reversion of epigenetic silencing of the PRKD1 promoter blocks breast tumor cell invasion and metastasis

Borges, S., Döppler, H., Perez, E. A., Andorfer, C. A., Sun, Z. D., Anastasiadis, P. Z., Thompson, E. A., Geiger, X. J. & Storz, P., Aug 23 2013, In : Breast Cancer Research. 15, 2, R66.

Research output: Contribution to journalArticle

Epigenomics
Protein Kinases
decitabine
Breast Neoplasms
Neoplasm Metastasis
10 Citations (Scopus)

Phosphorylation-mediated 14-3-3 protein binding regulates the function of the rho-specific guanine nucleotide exchange factor (RhoGEF) syx

Ngok, S. P., Geyer, R., Kourtidis, A., Storz, P. & Anastasiadis, P. Z., Mar 1 2013, In : Journal of Biological Chemistry. 288, 9, p. 6640-6650 11 p.

Research output: Contribution to journalArticle

Rho Guanine Nucleotide Exchange Factors
14-3-3 Proteins
Guanine Nucleotide Exchange Factors
Phosphorylation
Protein Binding
21 Citations (Scopus)

Protein kinase D1-mediated phosphorylations regulate Vasodilator-stimulated phosphoprotein (VASP) localization and cell migration

Döppler, H. R., Bastea, L. I., Lewis-Tuffin, L. J., Anastasiadis, P. Z. & Storz, P., Aug 23 2013, In : Journal of Biological Chemistry. 288, 34, p. 24382-24393 12 p.

Research output: Contribution to journalArticle

Phosphorylation
Protein Kinases
Cell Movement
Focal Adhesions
Actins
45 Citations (Scopus)

Targeting Src Family Kinases Inhibits Bevacizumab-Induced Glioma Cell Invasion

Huveldt, D., Lewis-Tuffin, L. J., Carlson, B. L., Schroeder, M. A., Rodriguez, F., Giannini, C., Galanis, E., Sarkaria, J. N. & Anastasiadis, P. Z., Feb 14 2013, In : PLoS One. 8, 2, e56505.

Research output: Contribution to journalArticle

cell invasion
src-Family Kinases
Glioma
phosphotransferases (kinases)
Glioblastoma
21 Citations (Scopus)

TEM4 is a junctional Rho GEF required for cell-cell adhesion, monolayer integrity and barrier function

Ngok, S. P., Geyer, R., Kourtidis, A., Mitin, N., Feathers, R., Der, C. & Anastasiadis, P. Z., 2013, In : Journal of Cell Science. 126, 15, p. 3271-3277 7 p.

Research output: Contribution to journalArticle

Rho Guanine Nucleotide Exchange Factors
Tumor Biomarkers
Cell Adhesion
Intercellular Junctions
rho GTP-Binding Proteins
17 Citations (Scopus)

The Rho guanine nucleotide exchange factor Syx regulates the balance of dia and ROCK activities to promote polarized-cancer-cell migration

Dachsel, J. C., Ngok, S. P., Lewis-Tuffin, L. J., Kourtidis, A., Geyer, R., Johnston, L., Feathers, R. & Anastasiadis, P. Z., 2013, In : Molecular and Cellular Biology. 33, 24, p. 4909-4918 10 p.

Research output: Contribution to journalArticle

Rho Guanine Nucleotide Exchange Factors
Cell Movement
Actins
Actin Depolymerizing Factors
Guanine Nucleotide Exchange Factors
2012
124 Citations (Scopus)

E-cadherin's dark side: Possible role in tumor progression

Rodriguez, F. J., Lewis-Tuffin, L. J. & Anastasiadis, P. Z., Aug 2012, In : Biochimica et Biophysica Acta - Reviews on Cancer. 1826, 1, p. 23-31 9 p.

Research output: Contribution to journalArticle

Cadherins
Neoplasms
Epithelial-Mesenchymal Transition
Down-Regulation
Inflammatory Breast Neoplasms
56 Citations (Scopus)

VEGF and angiopoietin-1 exert opposing effects on cell junctions by regulating the Rho GEF Syx

Ngok, S. P., Geyer, R., Liu, M., Kourtidis, A., Agrawal, S., Wu, C., Seerapu, H. R., Lewis-Tuffin, L. J., Moodie, K. L., Huveldt, D., Marx, R., Baraban, J. M., Storz, P., Horowitz, A. & Anastasiadis, P. Z., Dec 2012, In : Journal of Cell Biology. 199, 7, p. 1103-1115 13 p.

Research output: Contribution to journalArticle

Angiopoietin-1
Intercellular Junctions
Vascular Endothelial Growth Factor A
Endothelial Cells
Guanine Nucleotide Exchange Factors
2010
92 Citations (Scopus)

Misregulated E-Cadherin expression associated with an aggressive brain tumor phenotype

Lewis-Tuffin, L. J., Rodriguez, F., Giannini, C., Scheithauer, B., Necela, B. M., Sarkaria, J. N. & Anastasiadis, P. Z., 2010, In : PLoS One. 5, 10, e13665.

Research output: Contribution to journalArticle

cadherins
Cadherins
Brain Neoplasms
Tumors
Brain
102 Citations (Scopus)

Pathway signature and cellular differentiation in clear cell renal cell carcinoma

Tun, H. W., Marlow, L. A., von Roemeling, C. A., Cooper, S. J., Kreinest, P., Wu, K., Luxon, B. A., Sinha, M., Anastasiadis, P. Z. & Copland, J. A. III., 2010, In : PLoS One. 5, 5, e10696.

Research output: Contribution to journalArticle

kidney cells
Renal Cell Carcinoma
Gene expression
carcinoma
Cells
24 Citations (Scopus)

The 19-amino acid insertion in the tumor-associated splice isoform Rac1b confers specific binding to p120 catenin

Orlichenko, L., Geyer, R., Yanagisawa, M., Khauv, D., Radisky, E. S., Anastasiadis, P. Z. & Radisky, D. C., Jun 18 2010, In : Journal of Biological Chemistry. 285, 25, p. 19153-19161 9 p.

Research output: Contribution to journalArticle

Tumors
Protein Isoforms
GTP Phosphohydrolases
Amino Acids
Cell Movement
2008
104 Citations (Scopus)

A p120 catenin isoform switch affects rho activity, induces tumor cell invasion, and predicts metastatic disease

Yanagisawa, M., Huveldt, D., Kreinest, P., Lohse, C. M., Cheville, J. C., Parker, A., Copland, J. A. III. & Anastasiadis, P. Z., Jun 27 2008, In : Journal of Biological Chemistry. 283, 26, p. 18344-18354 11 p.

Research output: Contribution to journalArticle

Tumors
Protein Isoforms
Cells
Switches
Neoplasms
76 Citations (Scopus)

p120 catenin induces opposing effects on tumor cell growth depending on E-cadherin expression

Soto, E., Yanagisawa, M., Marlow, L. A., Copland, J. A. III., Perez, E. A. & Anastasiadis, P. Z., Nov 17 2008, In : Journal of Cell Biology. 183, 4, p. 737-749 13 p.

Research output: Contribution to journalArticle

Cadherins
Growth
Neoplasms
Phenotype
Guanosine
33 Citations (Scopus)

Synapses are regulated by the cytoplasmic tyrosine kinase Fer in a pathway mediated by p120catenin, Fer, SHP-2, and β-catenin

Lee, S. H., Peng, I. F., Ng, Y. G., Yanagisawa, M., Bamji, S. X., Elia, L. P., Balsamo, J., Lilien, J., Anastasiadis, P. Z., Ullian, E. M. & Reichardt, L. F., Dec 1 2008, In : Journal of Cell Biology. 183, 5, p. 893-908 16 p.

Research output: Contribution to journalArticle

Catenins
Protein-Tyrosine Kinases
Synapses
Synaptic Vesicles
Protein Phosphatase 2
2007
22 Citations (Scopus)

Functional genomic analysis reveals cross-talk between peroxisome proliferator-activated receptor γ and calcium signaling in human colorectal cancer cells

Bush, C. R., Havens, J. M., Necela, B. M., Su, W., Chen, L., Yanagisawa, M., Anastasiadis, P. Z., Guerra, R., Luxon, B. A. & Thompson, E. A., Aug 10 2007, In : Journal of Biological Chemistry. 282, 32, p. 23387-23401 15 p.

Research output: Contribution to journalArticle

Peroxisome Proliferator-Activated Receptors
Calcium Signaling
Colorectal Neoplasms
Cells
Calcium
138 Citations (Scopus)

p120-ctn: A nexus for contextual signaling via Rho GTPases

Anastasiadis, P. Z., Jan 2007, In : Biochimica et Biophysica Acta - Molecular Cell Research. 1773, 1, p. 34-46 13 p.

Research output: Contribution to journalArticle

rho GTP-Binding Proteins
Armadillo Domain Proteins
Neuronal Plasticity
Cadherins
Cell Movement
2006
17 Citations (Scopus)

Dual regulation of Rho and Rac by p120 catenin controls adipocyte plasma membrane trafficking

Hou, J. C., Shigematsu, S., Crawford, H. C., Anastasiadis, P. Z. & Pessin, J. E., Aug 18 2006, In : Journal of Biological Chemistry. 281, 33, p. 23307-23312 6 p.

Research output: Contribution to journalArticle

Cell membranes
Adipocytes
Cell Membrane
Cadherins
ADP-Ribosylation Factors
99 Citations (Scopus)

p120 catenin is essential for mesenchymal cadherin-mediated regulation of cell motility and invasiveness

Yanagisawa, M. & Anastasiadis, P. Z., Sep 25 2006, In : Journal of Cell Biology. 174, 7, p. 1087-1096 10 p.

Research output: Contribution to journalArticle

Cadherins
Cell Movement
delta catenin
Phenotype
Up-Regulation
45 Citations (Scopus)

Peroxisome proliferator-activated receptor γ promotes epithelial to mesenchymal transformation by Rho GTPase-dependent activation of ERK1/2

Chen, L., Necela, B. M., Su, W., Yanagisawa, M., Anastasiadis, P. Z., Fields, A. P. & Thompson, E. A., Aug 25 2006, In : Journal of Biological Chemistry. 281, 34, p. 24575-24587 13 p.

Research output: Contribution to journalArticle

rho GTP-Binding Proteins
Peroxisome Proliferator-Activated Receptors
Epithelial-Mesenchymal Transition
Chemical activation
Phosphorylation
28 Citations (Scopus)

RS5444, a novel PPARγ agonist, regulates aspects of the differentiated phenotype in nontransformed intestinal epithelial cells

Chen, L., Bush, C. R., Necela, B. M., Su, W., Yanagisawa, M., Anastasiadis, P. Z., Fields, A. P. & Thompson, E. A., Jun 7 2006, In : Molecular and Cellular Endocrinology. 251, 1-2, p. 17-32 16 p.

Research output: Contribution to journalArticle

PPAR gamma
Epithelial Cells
Phenotype
Rats
rosiglitazone
20 Citations (Scopus)

The role of cadherins and catenins in gliomagenesis.

Barami, K., Lewis-Tuffin, L. & Anastasiadis, P. Z., 2006, In : Neurosurgical Focus. 21, 4

Research output: Contribution to journalArticle

Catenins
Cadherins
Cell Adhesion
Glioma
Cell Adhesion Molecules
2005
242 Citations (Scopus)

Diverse compounds mimic Alzheimer disease-causing mutations by augmenting Aβ42 production

Kukar, T., Murphy, M. P., Eriksen, J. L., Sagi, S. A., Weggen, S., Smith, T. E., Ladd, T., Khan, M. A., Kache, R., Beard, J., Dodson, M., Merit, S., Ozols, V. V., Anastasiadis, P. Z., Das, P., Fauq, A., Koo, E. H. & Golde, T. E., May 2005, In : Nature Medicine. 11, 5, p. 545-550 6 p.

Research output: Contribution to journalArticle

Non-Steroidal Anti-Inflammatory Agents
Amyloid Precursor Protein Secretases
Alzheimer Disease
Celecoxib
Terpenes
2004
109 Citations (Scopus)

A Novel Interaction between Kinesin and p120 Modulates p120 Localization and Function

Yanagisawa, M., Kaverina, I. N., Wang, A., Fujita, Y., Reynolds, A. B. & Anastasiadis, P. Z., Mar 5 2004, In : Journal of Biological Chemistry. 279, 10, p. 9512-9521 10 p.

Research output: Contribution to journalArticle

Kinesin
Microtubules
Cadherins
Armadillos
Nocodazole
105 Citations (Scopus)

Continuous association of cadherin with β-catenin requires the non-receptor tyrosine-kinase Fer

Xu, G., Craig, A. W. B., Greer, P., Miller, M., Anastasiadis, P. Z., Lilien, J. & Balsamo, J., Jul 1 2004, In : Journal of Cell Science. 117, 15, p. 3207-3219 13 p.

Research output: Contribution to journalArticle

Catenins
Cadherins
Protein-Tyrosine Kinases
Tyrosine
Phosphorylation
116 Citations (Scopus)

Protein kinase c (PKC) βII induces cell invasion through a Ras/Mek-, PKCι/Rac 1-dependent signaling pathway

Zhang, J., Anastasiadis, P. Z., Liu, Y., Thompson, E. A. & Fields, A. P., May 21 2004, In : Journal of Biological Chemistry. 279, 21, p. 22118-22123 6 p.

Research output: Contribution to journalArticle

ras Proteins
Protein Kinases
Protein Kinase C
Rats
Epithelial Cells
112 Citations (Scopus)

Protein kinase Cι is required for Ras transformation and colon carcinogenesis in vivo

Murray, N. R., Jamieson, L., Yu, W., Zhang, J., Gökmen-Polar, Y., Sier, D., Anastasiadis, P. Z., Gatalica, Z., Thompson, E. A. & Fields, A. P., Mar 15 2004, In : Journal of Cell Biology. 164, 6, p. 797-802 6 p.

Research output: Contribution to journalArticle

Protein Kinase C
Colon
Carcinogenesis
Carcinogens
Phosphotransferases
76 Citations (Scopus)

Vertebrate development requires ARVCF and p120 catenins and their interplay with RhoA and Rac

Fang, X., Ji, H., Kim, S. W., Park, J. I., Vaught, T. G., Anastasiadis, P. Z., Ciesiolka, M. & McCrea, P. D., Apr 12 2004, In : Journal of Cell Biology. 165, 1, p. 87-98 12 p.

Research output: Contribution to journalArticle

Cadherins
Vertebrates
Embryonic Development
Armadillos
DiGeorge Syndrome
2002
412 Citations (Scopus)

A novel role for p120 catenin in E-cadherin function

Ireton, R. C., Davis, M. A., Van Hengel, J., Mariner, D. J., Barnes, K., Thoreson, M. A., Anastasiadis, P. Z., Matrisian, L., Bundy, L. M., Sealy, L., Gilbert, B., Van Roy, F. & Reynolds, A. B., Nov 11 2002, In : Journal of Cell Biology. 159, 3, p. 465-476 12 p.

Research output: Contribution to journalArticle

Cadherins
delta catenin
Adhesiveness
Cell Adhesion
Half-Life
2001
118 Citations (Scopus)

Identification of Src Phosphorylation Sites in the Catenin p120 ctn

Mariner, D. J., Anastasiadis, P. Z., Keilhack, H., Böhmer, F. D., Wang, J. & Reynolds, A. B., Jul 27 2001, In : Journal of Biological Chemistry. 276, 30, p. 28006-28013 8 p.

Research output: Contribution to journalArticle

Catenins
Phosphorylation
Tyrosine
Cadherins
Phenylalanine
216 Citations (Scopus)

Regulation of Rho GTPases by p120-catenin

Anastasiadis, P. Z. & Reynolds, A. B., Oct 1 2001, In : Current Opinion in Cell Biology. 13, 5, p. 604-610 7 p.

Research output: Contribution to journalArticle

rho GTP-Binding Proteins
Phenotype
Cadherins
Adhesives
Carcinoma
35 Citations (Scopus)

Tetrahydrobiopterin Enhances Apoptotic PC12 Cell Death following Withdrawal of Trophic Support

Anastasiadis, P. Z., Jiang, H., Bezin, L., Kuhn, D. M. & Levine, R. A., Mar 23 2001, In : Journal of Biological Chemistry. 276, 12, p. 9050-9058 9 p.

Research output: Contribution to journalArticle

PC12 Cells
Cell death
Cell Death
Apoptosis
Cell Cycle
2000
352 Citations (Scopus)

Inhibition of RhoA by p120 catenin

Anastasiadis, P. Z., Moon, S. Y., Thoreson, M. A., Mariner, D. J., Crawford, H. C., Zheng, Y. & Reynolds, A. B., Sep 2000, In : Nature Cell Biology. 2, 9, p. 637-644 8 p.

Research output: Contribution to journalArticle

Cadherins
Cluster Analysis
Adherens Junctions
Stress Fibers
Neurites
375 Citations (Scopus)

Selective uncoupling of p120(ctn) from E-cadherin disrupts strong adhesion

Thoreson, M. A., Anastasiadis, P. Z., Daniel, J. M., Ireton, R. C., Wheelock, M. J., Johnson, K. R., Hummingbird, D. K. & Reynolds, A. B., Jan 10 2000, In : Journal of Cell Biology. 148, 1, p. 189-201 13 p.

Research output: Contribution to journalArticle

Cadherins
Catenins
Actin Cytoskeleton
Cell Adhesion
delta catenin