Projects per year
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- 2 Similar Profiles
DNA Damage
Medicine & Life Sciences
gemcitabine
Medicine & Life Sciences
Phosphorylation
Medicine & Life Sciences
tanespimycin
Medicine & Life Sciences
Phosphatidylinositol 3-Kinase
Medicine & Life Sciences
Phosphotransferases
Medicine & Life Sciences
Cells
Chemical Compounds
DNA Repair
Medicine & Life Sciences
Network
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Projects 1997 2021
Cyclin-Dependent Kinases
Ovarian Neoplasms
Homologous Recombination
Neoplasms
Phosphorylation
Acute Myeloid Leukemia
Myeloid Cells
Therapeutics
Biomarkers
Anthracyclines
Predoctoral Training Program in Molecular Pharmacology
Karnitz, L. M. & Ames, M.
8/10/05 → 6/30/21
Project: Research project
Pharmacology
Students
Education
Research
Molecular Biology
tanespimycin
HSP90 Heat-Shock Proteins
gemcitabine
Ovarian Neoplasms
Cisplatin
DNA Damage
Genomic Instability
Cell Cycle Checkpoints
DNA Repair
DNA
Research Output 1984 2019
- 6345 Citations
- 41 h-Index
- 75 Article
Effect of CHK1 Inhibition on CPX-351 Cytotoxicity in vitro and ex vivo
Vincelette, N. D., Ding, H., Huehls, A. M., Flatten, K. S., Kelly, R. L., Kohorst, M. A., Webster, J., Hess, A. D., Pratz, K. W., Karnitz, L. M. & Kaufmann, S. H., Dec 1 2019, In : Scientific reports. 9, 1, 3617.Research output: Contribution to journal › Article
Open Access
Acute Myeloid Leukemia
Cytarabine
Daunorubicin
G2 Phase Cell Cycle Checkpoints
In Vitro Techniques
6
Citations
(Scopus)
Carnitine Palmitoyltransferase 1A Has a Lysine Succinyltransferase Activity
Kurmi, K., Hitosugi, S., Wiese, E. K., Boakye-Agyeman, F., Gonsalves, W., Lou, Z., Karnitz, L. M., Goetz, M. P. & Hitosugi, T. D., Feb 6 2018, In : Cell Reports. 22, 6, p. 1365-1373 9 p.Research output: Contribution to journal › Article
Carnitine O-Palmitoyltransferase
Lysine
Phosphopyruvate Hydratase
Isotope Labeling
Mutation
1
Citation
(Scopus)
Tyrosine Phosphorylation of Mitochondrial Creatine Kinase 1 Enhances a Druggable Tumor Energy Shuttle Pathway
Kurmi, K., Hitosugi, S., Yu, J., Boakye-Agyeman, F., Wiese, E. K., Larson, T. R., Dai, Q., Machida, Y., Lou, Z., Wang, L. M., Boughey, J. C., Kaufmann, S. H., Goetz, M. P., Karnitz, L. M. & Hitosugi, T. D., Dec 4 2018, In : Cell Metabolism. 28, 6, p. 833-847.e8Research output: Contribution to journal › Article
Mitochondrial Form Creatine Kinase
Phosphocreatine
Tyrosine
Phosphorylation
Breast Neoplasms
12
Citations
(Scopus)
A phase 1 study of the PARP inhibitor veliparib in combination with temozolomide in acute myeloid leukemia
Gojo, I., Beumer, J. H., Pratz, K. W., McDevitt, M. A., Baer, M. R., Blackford, A. L., Smith, B. D., Gore, S. D., Carraway, H. E., Showel, M. M., Levis, M. J., Dezern, A. E., Gladstone, D. E., Ji, J. J., Wang, L., Kinders, R. J., Pouquet, M., Ali-Walbi, I., Rudek, M. A., Poh, W. & 5 others, Feb 1 2017, In : Clinical Cancer Research. 23, 3, p. 697-706 10 p.Research output: Contribution to journal › Article
temozolomide
Acute Myeloid Leukemia
Methylation
Phosphorylation
Polymers
11
Citations
(Scopus)
A phase I study of topotecan, carboplatin and the PARP inhibitor veliparib in acute leukemias, aggressive myeloproliferative neoplasms, and chronic myelomonocytic leukemia
Pratz, K. W., Rudek, M. A., Gojo, I., Litzow, M. R., McDevitt, M. A., Ji, J., Karnitz, L. M., Herman, J. G., Kinders, R. J., Smith, B. D., Gore, S. D., Carraway, H. E., Showel, M. M., Gladstone, D. E., Levis, M. J., Tsai, H. L., Rosner, G., Chen, A., Kaufmann, S. H. & Karp, J. E., Feb 15 2017, In : Clinical Cancer Research. 23, 4, p. 899-907 9 p.Research output: Contribution to journal › Article
Leukemia, Myelomonocytic, Chronic
Topotecan
Carboplatin
Leukemia
Neoplasms