Projects per year
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- 2 Similar Profiles
DNA Damage
Medicine & Life Sciences
gemcitabine
Medicine & Life Sciences
Phosphorylation
Chemical Compounds
tanespimycin
Medicine & Life Sciences
Phosphatidylinositol 3-Kinase
Medicine & Life Sciences
Phosphotransferases
Medicine & Life Sciences
Cells
Chemical Compounds
DNA Repair
Medicine & Life Sciences
Network
Recent external collaboration on country level. Dive into details by clicking on the dots.
Projects 1997 2021
Cyclin-Dependent Kinases
Ovarian Neoplasms
Homologous Recombination
Neoplasms
Phosphorylation
Targeting Chk1 in Acute Myeloid Leukemia
7/24/15 → 6/30/20
Project: Research project › Research Project
Acute Myeloid Leukemia
Myeloid Cells
Therapeutics
Biomarkers
Anthracyclines
Predoctoral Training Program in Molecular Pharmacology
Karnitz, L. M. & Ames, M.
8/10/05 → 6/30/21
Project: Research project › Institutional National Research Service Award
Pharmacology
Students
Education
Research
Molecular Biology
Therapeutic targeting of HSP90-dependent signaling
4/1/04 → 2/28/10
Project: Research project › Research Project
tanespimycin
HSP90 Heat-Shock Proteins
gemcitabine
Ovarian Neoplasms
Cisplatin
ANALYSIS OF A DNA DAMAGE INDUCIBLE CHECKPOINT COMPLEX
12/1/99 → 6/30/11
Project: Research project › Research Project, High Priority, Short Term Project Award
DNA Damage
Genomic Instability
Cell Cycle Checkpoints
DNA Repair
DNA
Research Output 1984 2018
- 6252 Citations
- 41 h-Index
- 73 Article
5
Citations
Carnitine Palmitoyltransferase 1A Has a Lysine Succinyltransferase Activity
Kurmi, K., Hitosugi, S., Wiese, E. K., Boakye-Agyeman, F., Gonsalves, W., Lou, Z., Karnitz, L. M., Goetz, M. P. & Hitosugi, T. D., Feb 6 2018, In : Cell Reports. 22, 6, p. 1365-1373 9 p.Research output: Contribution to journal › Article
Carnitine O-Palmitoyltransferase
Lysine
Phosphopyruvate Hydratase
Isotope Labeling
Mutation
9
Citations
A phase 1 study of the PARP inhibitor veliparib in combination with temozolomide in acute myeloid leukemia
Gojo, I., Beumer, J. H., Pratz, K. W., McDevitt, M. A., Baer, M. R., Blackford, A. L., Smith, B. D., Gore, S. D., Carraway, H. E., Showel, M. M., Levis, M. J., Dezern, A. E., Gladstone, D. E., Ji, J. J., Wang, L., Kinders, R. J., Pouquet, M., Ali-Walbi, I., Rudek, M. A., Poh, W. & 5 others, Feb 1 2017, In : Clinical Cancer Research. 23, 3, p. 697-706 10 p.Research output: Contribution to journal › Article
temozolomide
Acute Myeloid Leukemia
Methylation
Phosphorylation
Polymers
6
Citations
A phase I study of topotecan, carboplatin and the PARP inhibitor veliparib in acute leukemias, aggressive myeloproliferative neoplasms, and chronic myelomonocytic leukemia
Pratz, K. W., Rudek, M. A., Gojo, I., Litzow, M. R., McDevitt, M. A., Ji, J., Karnitz, L. M., Herman, J. G., Kinders, R. J., Smith, B. D., Gore, S. D., Carraway, H. E., Showel, M. M., Gladstone, D. E., Levis, M. J., Tsai, H. L., Rosner, G., Chen, A., Kaufmann, S. H. & Karp, J. E., Feb 15 2017, In : Clinical Cancer Research. 23, 4, p. 899-907 9 p.Research output: Contribution to journal › Article
Leukemia, Myelomonocytic, Chronic
Topotecan
Carboplatin
Leukemia
Neoplasms
6
Citations
Randomized phase II trial of cytosine arabinoside with and without the CHK1 inhibitor MK-8776 in relapsed and refractory acute myeloid leukemia
Webster, J. A., Tibes, R., Morris, L., Blackford, A. L., Litzow, M. R., Patnaik, M. M., Rosner, G. L., Gojo, I., Kinders, R., Wang, L., Doyle, L. A., Huntoon, C. J., Karnitz, L. M., Kaufmann, S. H., Karp, J. E. & Smith, B. D., Oct 1 2017, In : Leukemia Research. 61, p. 108-116 9 p.Research output: Contribution to journal › Article
Cytarabine
Acute Myeloid Leukemia
DNA Damage
Cell Cycle Checkpoints
MK-8776
11
Citations
Genomically incorporated 5-fluorouracil that escapes ung-initiated base excision repair blocks dna replication and activates homologous recombination
Huehls, A. M., Huntoon, C. J., Joshi, P. M., Baehr, C. A., Wagner, J. M., Wang, X., Lee, M. Y. & Karnitz, L. M., Jan 1 2016, In : Molecular Pharmacology. 89, 1, p. 53-62 10 p.Research output: Contribution to journal › Article
Homologous Recombination
Fluorouracil
DNA Repair
Floxuridine
Uracil-DNA Glycosidase