Projects per year
Fingerprint Dive into the research topics where Larry M Karnitz is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
- 2 Similar Profiles
DNA Damage
Medicine & Life Sciences
gemcitabine
Medicine & Life Sciences
Phosphorylation
Medicine & Life Sciences
tanespimycin
Medicine & Life Sciences
Phosphatidylinositol 3-Kinase
Medicine & Life Sciences
Phosphotransferases
Medicine & Life Sciences
Cells
Chemical Compounds
DNA Repair
Medicine & Life Sciences
Network
Recent external collaboration on country level. Dive into details by clicking on the dots.
Projects 1997 2021
Cyclin-Dependent Kinases
Ovarian Neoplasms
Homologous Recombination
Neoplasms
Phosphorylation
Acute Myeloid Leukemia
Myeloid Cells
Therapeutics
Biomarkers
Anthracyclines
Predoctoral Training Program in Molecular Pharmacology
Karnitz, L. M. & Ames, M.
8/10/05 → 6/30/21
Project: Research project
Pharmacology
Students
Education
Research
Molecular Biology
tanespimycin
HSP90 Heat-Shock Proteins
gemcitabine
Ovarian Neoplasms
Cisplatin
DNA Damage
Genomic Instability
Cell Cycle Checkpoints
DNA Repair
DNA
Research Output 1984 2019
- 6502 Citations
- 41 Scopus h-Index
- 76 Article
Effect of CHK1 Inhibition on CPX-351 Cytotoxicity in vitro and ex vivo
Vincelette, N. D., Ding, H., Huehls, A. M., Flatten, K. S., Kelly, R. L., Kohorst, M. A., Webster, J., Hess, A. D., Pratz, K. W., Karnitz, L. M. & Kaufmann, S. H., Dec 1 2019, In : Scientific reports. 9, 1, 3617.Research output: Contribution to journal › Article
Open Access
Acute Myeloid Leukemia
Cytarabine
Daunorubicin
G2 Phase Cell Cycle Checkpoints
In Vitro Techniques
ZC3H18 specifically binds and activates the BRCA1 promoter to facilitate homologous recombination in ovarian cancer
Kanakkanthara, A., Huntoon, C. J., Hou, X., Zhang, M., Heinzen, E. P., O’Brien, D. R., Oberg, A. L., John Weroha, S., Kaufmann, S. H. & Karnitz, L. M., Dec 1 2019, In : Nature communications. 10, 1, 4632.Research output: Contribution to journal › Article
Open Access
Homologous Recombination
Ovarian Neoplasms
grade
cancer
Messenger RNA
10
Citations
(Scopus)
Carnitine Palmitoyltransferase 1A Has a Lysine Succinyltransferase Activity
Kurmi, K., Hitosugi, S., Wiese, E. K., Boakye-Agyeman, F., Gonsalves, W., Lou, Z., Karnitz, L. M., Goetz, M. P. & Hitosugi, T. D., Feb 6 2018, In : Cell Reports. 22, 6, p. 1365-1373 9 p.Research output: Contribution to journal › Article
Carnitine O-Palmitoyltransferase
Lysine
Phosphopyruvate Hydratase
Isotope Labeling
Mutation
4
Citations
(Scopus)
Tyrosine Phosphorylation of Mitochondrial Creatine Kinase 1 Enhances a Druggable Tumor Energy Shuttle Pathway
Kurmi, K., Hitosugi, S., Yu, J., Boakye-Agyeman, F., Wiese, E. K., Larson, T. R., Dai, Q., Machida, Y., Lou, Z., Wang, L. M., Boughey, J. C., Kaufmann, S. H., Goetz, M. P., Karnitz, L. M. & Hitosugi, T. D., Dec 4 2018, In : Cell Metabolism. 28, 6, p. 833-847.e8Research output: Contribution to journal › Article
Mitochondrial Form Creatine Kinase
Phosphocreatine
Tyrosine
Phosphorylation
Breast Neoplasms
20
Citations
(Scopus)
A phase 1 study of the PARP inhibitor veliparib in combination with temozolomide in acute myeloid leukemia
Gojo, I., Beumer, J. H., Pratz, K. W., McDevitt, M. A., Baer, M. R., Blackford, A. L., Smith, B. D., Gore, S. D., Carraway, H. E., Showel, M. M., Levis, M. J., Dezern, A. E., Gladstone, D. E., Ji, J. J., Wang, L., Kinders, R. J., Pouquet, M., Ali-Walbi, I., Rudek, M. A., Poh, W. & 5 others, , Feb 1 2017, In : Clinical Cancer Research. 23, 3, p. 697-706 10 p.Research output: Contribution to journal › Article
temozolomide
Acute Myeloid Leukemia
Methylation
Phosphorylation
Polymers