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Larry M Karnitz, PhD

  • 6609 Citations
  • 41 Scopus h-Index
1984 …2021

Research output per year

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Projects

CDK12 in Ovarian Cancer

Karnitz, L. M.

National Institutes of Health

12/1/15 → 11/30/20

Project: Research project

    • Targeting Chk1 in Acute Myeloid Leukemia

    Karnitz, L. M.

    National Institutes of Health

    7/24/15 → 6/30/20

    Project: Research project

    • Predoctoral Training Program in Molecular Pharmacology

    Karnitz, L. M. & Ames, M.

    National Institutes of Health

    8/10/05 → 6/30/21

    Project: Research project

    • Therapeutic targeting of HSP90-dependent signaling

    Karnitz, L. M.

    National Institutes of Health

    4/1/04 → 2/28/10

    Project: Research project

    • ANALYSIS OF A DNA DAMAGE INDUCIBLE CHECKPOINT COMPLEX

    Karnitz, L. M.

    National Institutes of Health

    12/1/99 → 6/30/11

    Project: Research project

    • Research Output

    • 6609 Citations
    • 41 Scopus h-Index
    • 72 Article
    • 4 Review article

    Effect of CHK1 Inhibition on CPX-351 Cytotoxicity in vitro and ex vivo

    Vincelette, N. D., Ding, H., Huehls, A. M., Flatten, K. S., Kelly, R. L., Kohorst, M. A., Webster, J., Hess, A. D., Pratz, K. W., Karnitz, L. M. & Kaufmann, S. H., Dec 1 2019, In : Scientific reports. 9, 1, 3617.

    Research output: Contribution to journal › Article

    Open Access
    • 1 Scopus citations

    ZC3H18 specifically binds and activates the BRCA1 promoter to facilitate homologous recombination in ovarian cancer

    Kanakkanthara, A., Huntoon, C. J., Hou, X., Zhang, M., Heinzen, E. P., O’Brien, D. R., Oberg, A. L., John Weroha, S., Kaufmann, S. H. & Karnitz, L. M., Dec 1 2019, In : Nature communications. 10, 1, 4632.

    Research output: Contribution to journal › Article

    Open Access

    • Carnitine Palmitoyltransferase 1A Has a Lysine Succinyltransferase Activity

    Kurmi, K., Hitosugi, S., Wiese, E. K., Boakye-Agyeman, F., Gonsalves, W., Lou, Z., Karnitz, L. M., Goetz, M. P. & Hitosugi, T. D., Feb 6 2018, In : Cell Reports. 22, 6, p. 1365-1373 9 p.

    Research output: Contribution to journal › Article

    • 12 Scopus citations

    Tyrosine Phosphorylation of Mitochondrial Creatine Kinase 1 Enhances a Druggable Tumor Energy Shuttle Pathway

    Kurmi, K., Hitosugi, S., Yu, J., Boakye-Agyeman, F., Wiese, E. K., Larson, T. R., Dai, Q., Machida, Y., Lou, Z., Wang, L. M., Boughey, J. C., Kaufmann, S. H., Goetz, M. P., Karnitz, L. M. & Hitosugi, T. D., Dec 4 2018, In : Cell Metabolism. 28, 6, p. 833-847.e8

    Research output: Contribution to journal › Article

    • 6 Scopus citations

    A phase 1 study of the PARP inhibitor veliparib in combination with temozolomide in acute myeloid leukemia

    Gojo, I., Beumer, J. H., Pratz, K. W., McDevitt, M. A., Baer, M. R., Blackford, A. L., Smith, B. D., Gore, S. D., Carraway, H. E., Showel, M. M., Levis, M. J., Dezern, A. E., Gladstone, D. E., Ji, J. J., Wang, L., Kinders, R. J., Pouquet, M., Ali-Walbi, I., Rudek, M. A., Poh, W. & 5 others, Herman, J. G., Karnitz, L. M., Kaufmann, S. H., Chen, A. & Karp, J. E., Feb 1 2017, In : Clinical Cancer Research. 23, 3, p. 697-706 10 p.

    Research output: Contribution to journal › Article

    • 23 Scopus citations