• 20323 Citations
  • 79 Scopus h-Index
1974 …2020

Research output per year

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Research Output

2011

Nonoxidative free fatty acid disposal is greater in young women than men

Koutsari, C., Basu, R., Rizza, R. A., Nair, K. S., Khosla, S. & Jensen, M. D., Feb 1 2011, In : Journal of Clinical Endocrinology and Metabolism. 96, 2, p. 541-547 7 p.

Research output: Contribution to journalArticle

33 Scopus citations

Preferential skeletal muscle myosin loss in response to mechanical silencing in a novel rat intensive care unit model: Underlying mechanisms

Ochala, J., Gustafson, A. M., Diez, M. L., Renaud, G., Li, M., Aare, S., Qaisar, R., Banduseela, V. C., Hedström, Y., Tang, X., Dworkin, B., Ford, G. C., Nair, K. S., Perera, S., Gautel, M. & Larsson, L., Apr 1 2011, In : Journal of Physiology. 589, 8, p. 2007-2026 20 p.

Research output: Contribution to journalArticle

81 Scopus citations

Unique cellular and mitochondrial defects mediate FK506-induced islet β-cell dysfunction

Rostambeigi, N., Lanza, I. R., Dzeja, P. P., Deeds, M. C., Irving, B. A., Reddi, H. V., Madde, P., Zhang, S., Asmann, Y. W., Anderson, J. M., Schimke, J. M., Nair, K. S., Eberhardt, N. L. & Kudva, Y. C., Mar 27 2011, In : Transplantation. 91, 6, p. 615-623 9 p.

Research output: Contribution to journalArticle

35 Scopus citations
2010

Age, obesity, and sex effects on insulin sensitivity and skeletal muscle mitochondrial function

Karakelides, H., Irving, B. A., Short, K. R., O'Brien, P. & Sreekumaran Nair, K., Jan 1 2010, In : Diabetes. 59, 1, p. 89-97 9 p.

Research output: Contribution to journalArticle

137 Scopus citations

Bi-linear regression for 18O quantification: Modeling across the elution profile

Eckel-Passow, J. E., Mahoney, D. W., Oberg, A. L., Zenka, R. M., Johnson, K. L., Nair, K. S., Kudva, Y. C., Bergen, H. R. & Therneau, T. M., Dec 1 2010, In : Journal of Proteomics and Bioinformatics. 3, 12, p. 323-329 7 p.

Research output: Contribution to journalArticle

5 Scopus citations

Effects of Adiposity and 30 Days of Caloric Restriction Upon Protein Metabolism in Moderately vs. Severely Obese Women

Henderson, G. C., Nadeau, D., Horton, E. S. & Nair, K. S., Jan 1 2010, In : Obesity. 18, 6, p. 1135-1142 8 p.

Research output: Contribution to journalArticle

9 Scopus citations

Effects on lipoprotein particles of long-term dehydroepiandrosterone in elderly men and women and testosterone in elderly men

Srinivasan, M., Irving, B. A., Frye, R. L., O'Brien, P., Hartman, S. J., McConnell, J. P. & Nair, K. S., Apr 2010, In : Journal of Clinical Endocrinology and Metabolism. 95, 4, p. 1617-1625 9 p.

Research output: Contribution to journalArticle

16 Scopus citations

Identification of de novo synthesized and relatively older proteins: Accelerated oxidative damage to de novo synthesized apolipoprotein A-1 in type 1 diabetes

Jaleel, A., Henderson, G. C., Madden, B. J., Klaus, K. A., Morse, D. M., Gopala, S. & Nair, K. S., Oct 1 2010, In : Diabetes. 59, 10, p. 2366-2374 9 p.

Research output: Contribution to journalArticle

38 Scopus citations

Limited predictive ability of surrogate indices of insulin sensitivity/resistance in Asian-Indian men

Muniyappa, R., Irving, B. A., Unni, U. S., Briggs, W. M., Nair, K. S., Quon, M. J. & Kurpad, A. V., Dec 2010, In : American Journal of Physiology - Endocrinology and Metabolism. 299, 6, p. E1106-E1112

Research output: Contribution to journalArticle

11 Scopus citations

Mitochondrial DNA alterations and reduced mitochondrial function in aging

Hebert, S. L., Lanza, I. R. & Nair, K. S., Jul 1 2010, In : Mechanisms of Ageing and Development. 131, 7-8, p. 451-462 12 p.

Research output: Contribution to journalArticle

53 Scopus citations

Mitochondrial function as a determinant of life span

Lanza, I. R. & Nair, K. S., Jan 1 2010, In : Pflugers Archiv European Journal of Physiology. 459, 2, p. 277-289 13 p.

Research output: Contribution to journalReview article

94 Scopus citations

Mitochondrial metabolic function assessed in vivo and in vitro

Lanza, I. R. & Nair, K. S., Sep 1 2010, In : Current Opinion in Clinical Nutrition and Metabolic Care. 13, 5, p. 511-517 7 p.

Research output: Contribution to journalReview article

34 Scopus citations

Protein and energy metabolism in type 1 diabetes

Hebert, S. L. & Nair, K. S., Feb 1 2010, In : Clinical Nutrition. 29, 1, p. 13-17 5 p.

Research output: Contribution to journalReview article

43 Scopus citations

Quantitative metabolomics by 1H-NMR and LC-MS/MS confirms altered metabolic pathways in diabetes

Lanza, I. R., Zhang, S., Ward, L. E., Karakelides, H., Raftery, D. & Sreekumaran Nair, K., 2010, In : PloS one. 5, 5, e10538.

Research output: Contribution to journalArticle

176 Scopus citations

Regulation of skeletal muscle mitochondrial function: Genes to proteins

Lanza, I. R. & Sreekumaran Nair, K., Aug 2010, In : Acta Physiologica. 199, 4, p. 529-547 19 p.

Research output: Contribution to journalReview article

58 Scopus citations

The effect of branched chain amino acids on skeletal muscle mitochondrial function in young and elderly adults

Tatpati, L. L., Irving, B. A., Tom, A., Bigelow, M. L., Klaus, K., Short, K. R. & Nair, K. S., Feb 2010, In : Journal of Clinical Endocrinology and Metabolism. 95, 2, p. 894-902 9 p.

Research output: Contribution to journalArticle

28 Scopus citations
2009

Chapter 20: Functional Assessment of Isolated Mitochondria In Vitro

Lanza, I. R. & Nair, K. S., May 6 2009, Mitochondrial Function, Part B: Mitochondrial Protein Kinases, Protein Phosphatases and Mitochondrial Diseases. Allison, W. & Murphy, A. (eds.). B ed. p. 349-372 24 p. (Methods in Enzymology; vol. 457, no. B).

Research output: Chapter in Book/Report/Conference proceedingChapter

118 Scopus citations

Differential effects of insulin deprivation and systemic insulin treatment on plasma protein synthesis in type 1 diabetic people

Jaleel, A., Klaus, K. A., Morse, D. M., Karakelides, H., Ward, L. E., Irving, B. A. & Nair, K. S., Oct 1 2009, In : American Journal of Physiology - Endocrinology and Metabolism. 297, 4, p. E889-E897

Research output: Contribution to journalArticle

19 Scopus citations

Effect of dehydroepiandrosterone replacement on lipoprotein profile in hypoadrenal women

Srinivasan, M., Irving, B. A., Dhatariya, K., Klaus, K. A., Hartman, S. J., McConnell, J. P. & Nair, K. S., Mar 2009, In : Journal of Clinical Endocrinology and Metabolism. 94, 3, p. 761-764 4 p.

Research output: Contribution to journalArticle

17 Scopus citations

Effect of testosterone on insulin stimulated IRS1 ser phosphorylation in primary rat myotubes - A potential model for PCOS-related insulin resistance

Allemand, M. C., Irving, B. A., Asmann, Y. W., Klaus, K. A., Tatpati, L., Coddington, C. C. & Nair, S., Jan 26 2009, In : PloS one. 4, 1, e4274.

Research output: Contribution to journalArticle

44 Scopus citations

Erratum: Asian Indians have enhanced skeletal muscle mitochondrial capacity to product ATP in association with severe insulin resistance (Diabetes (2008) 57 (1166-1175))

Nair, K. S., Bigelow, M. L., Asmann, Y. W., Chow, L. S., Coenen-Schimke, J. M., Klaus, K. A., Guo, Z. K., Sreekumar, R. & Irving, B. A., Mar 1 2009, In : Diabetes. 58, 3, 1 p.

Research output: Contribution to journalComment/debate

Fatty acid metabolism in the elderly: Effects of dehydroepiandrosterone and testosterone replacement in hormonally deficient men and women

Koutsari, C., Ali, A. H., Nair, K. S., Rizza, R. A., O'Brien, P., Khosla, S. & Jensen, M. D., Sep 2009, In : Journal of Clinical Endocrinology and Metabolism. 94, 9, p. 3414-3423 10 p.

Research output: Contribution to journalArticle

21 Scopus citations

Higher muscle protein synthesis in women than men across the lifespan, and failure of androgen administration to amend age-related decrements

Henderson, G. C., Dhatariya, K., Ford, G. C., Klaus, K. A., Basu, R., Rizza, R. A., Jensen, M. D., Khosla, S., O'Brien, P. & Nair, K. S., Feb 2009, In : FASEB Journal. 23, 2, p. 631-641 11 p.

Research output: Contribution to journalArticle

62 Scopus citations

Impact of type 1 diabetes and insulin treatment on plasma levels and fractional synthesis rate of retinol-binding protein 4

Jourdan, M., Jaleel, A., Karakelides, H., Ford, G. C., Kahn, B. B. & Nair, K. S., Dec 2009, In : Journal of Clinical Endocrinology and Metabolism. 94, 12, p. 5125-5130 6 p.

Research output: Contribution to journalArticle

8 Scopus citations

Interdependence of signal processing and analysis of urine1H NMR spectra for metabolic profiling

Zhang, S., Zheng, C., Lanza, I. R., Nair, K. S., Raftery, D. & Vitek, O., Aug 1 2009, In : Analytical Chemistry. 81, 15, p. 6080-6088 9 p.

Research output: Contribution to journalArticle

40 Scopus citations

Muscle mitochondrial changes with aging and exercise

Lanza, I. R. & Nair, K. S., Jan 1 2009, In : American Journal of Clinical Nutrition. 89, 1, p. 467S-471S

Research output: Contribution to journalArticle

89 Scopus citations

Paradoxical coupling of triglyceride synthesis and fatty acid oxidation in skeletal muscle overexpressing DGAT1

Liu, L., Shi, X., Cheol, S. C., Shulman, G. I., Klaus, K., Nair, K. S., Schwartz, G. J., Zhang, Y., Goldberg, I. J. & Yu, Y. H., Nov 1 2009, In : Diabetes. 58, 11, p. 2516-2524 9 p.

Research output: Contribution to journalArticle

46 Scopus citations

Post-transcriptional gene silencing of ribosomal protein S6 kinase 1 restores insulin action in leucine-treated skeletal muscle

Deshmukh, A., Salehzadeh, F., Metayer-Coustard, S., Fahlman, R., Nair, K. S. & Al-Khalili, L., Apr 1 2009, In : Cellular and Molecular Life Sciences. 66, 8, p. 1457-1466 10 p.

Research output: Contribution to journalArticle

10 Scopus citations

Potential application of essential amino acid supplementation to treat sarcopenia in elderly people

Henderson, G. C., Irving, B. A. & Nair, K. S., May 2009, In : Journal of Clinical Endocrinology and Metabolism. 94, 5, p. 1524-1526 3 p.

Research output: Contribution to journalEditorial

18 Scopus citations

Reply to SN Thornton and K Hess

Lanza, I. R. & Nair, K. S., Jan 5 2009, In : American Journal of Clinical Nutrition. 89, 5, p. 1476-1477 2 p.

Research output: Contribution to journalLetter

28 Scopus citations

The effect of high glucocorticoid administration and food restriction on rodent skeletal muscle mitochondrial function and protein metabolism

You, Y. N., Short, K. R., Jourdan, M., Klaus, K. A., Walrand, S. & Nair, K. S., Apr 20 2009, In : PloS one. 4, 4, e5283.

Research output: Contribution to journalArticle

15 Scopus citations
2008

Asian indians have enhanced skeletal muscle mitochondrial capacity to produce ATP in association with severe insulin resistance

Nair, K. S., Bigelow, M. L., Asmann, Y. W., Chow, L. S., Coenen-Schimke, J. M., Klaus, K. A., Guo, Z. K., Sreekumar, R. & Irving, B. A., May 1 2008, In : Diabetes. 57, 5, p. 1166-1175 10 p.

Research output: Contribution to journalArticle

134 Scopus citations

Changes in body composition in women following treatment of overt and subclinical hyperthyroidism

Greenlund, L. J. S., Nair, K. S. & Brennan, M. D., Nov 2008, In : Endocrine Practice. 14, 8, p. 973-978 6 p.

Research output: Contribution to journalArticle

31 Scopus citations

Dehydroepiandrosterone in adrenal insufficiency and ageing

Bhagra, S., Nippoldt, T. B. & Nair, K. S., Jun 1 2008, In : Current Opinion in Endocrinology, Diabetes and Obesity. 15, 3, p. 239-243 5 p.

Research output: Contribution to journalReview article

23 Scopus citations

Dehydroepiandrosterone replacement therapy in hypoadrenal women: Protein anabolism and skeletal muscle function

Dhatariya, K. K., Greenlund, L. J. S., Bigelow, M. L., Thapa, P., Oberg, A. L., Ford, G. C., Schimke, J. M. & Nair, K. S., Nov 2008, In : Mayo Clinic proceedings. 83, 11, p. 1218-1225 8 p.

Research output: Contribution to journalArticle

9 Scopus citations

Diabetes and protein metabolism

Møller, N. & Nair, K. S., Jan 1 2008, In : Diabetes. 57, 1, p. 3-4 2 p.

Research output: Contribution to journalComment/debate

30 Scopus citations

Effect of oral amino acids on counterregulatory responses and cognitive function during insulin-induced hypoglycemia in nondiabetic and type 1 diabetic people

Rossetti, P., Porcellati, F., Ricci, N. B., Candeloro, P., Cioli, P., Sreekumaran Nair, K., Santeusanio, F., Bolli, G. B. & Fanelli, C. G., Jul 1 2008, In : Diabetes. 57, 7, p. 1905-1917 13 p.

Research output: Contribution to journalArticle

17 Scopus citations

Endurance exercise as a countermeasure for aging

Lanza, I. R., Short, D. K., Short, K. R., Raghavakaimal, S., Basu, R., Joyner, M. J., McConnell, J. P. & Nair, K. S., Nov 1 2008, In : Diabetes. 57, 11, p. 2933-2942 10 p.

Research output: Contribution to journalArticle

336 Scopus citations

Enhancement of muscle mitochondrial function by growth hormone

Short, K. R., Moller, N., Bigelow, M. L., Coenen-Schimke, J. & Nair, K. S., Feb 2008, In : Journal of Clinical Endocrinology and Metabolism. 93, 2, p. 597-604 8 p.

Research output: Contribution to journalArticle

58 Scopus citations

Frailty and its potential relevance to cardiovascular care

Singh, M., Alexander, K., Roger, V. L., Rihal, C. S., Whitson, H. E., Lerman, A., Jahangir, A. & Nair, K. S., Oct 2008, In : Mayo Clinic proceedings. 83, 10, p. 1146-1153 8 p.

Research output: Contribution to journalReview article

70 Scopus citations

Functional impact of high protein intake on healthy elderly people

Walrand, S., Short, K. R., Bigelow, M. L., Sweatt, A. J., Hutson, S. M. & Nair, K. S., Oct 2008, In : American Journal of Physiology - Endocrinology and Metabolism. 295, 4, p. E921-E928

Research output: Contribution to journalArticle

76 Scopus citations

In vivo measurement of synthesis rate of individual skeletal muscle mitochondrial proteins

Jaleel, A., Short, K. R., Asmann, Y. W., Klaus, K. A., Morse, D. M., Ford, G. C. & Nair, K. S., Nov 2008, In : American Journal of Physiology - Endocrinology and Metabolism. 295, 5, p. E1255-E1268

Research output: Contribution to journalArticle

60 Scopus citations

Lack of dehydroepiandrosterone effect on a combined endurance and resistance exercise program in postmenopausal women

Igwebuike, A., Irving, B. A., Bigelow, M. L., Short, K. R., McConnell, J. P. & Nair, K. S., Feb 2008, In : Journal of Clinical Endocrinology and Metabolism. 93, 2, p. 534-538 5 p.

Research output: Contribution to journalArticle

41 Scopus citations

The effects of growth hormone and/or testosterone on whole body protein kinetics and skeletal muscle gene expression in healthy elderly men: A randomized controlled trial

Giannoulis, M. G., Jackson, N., Shojaee-Moradie, F., Nair, K. S., Sonksen, P. H., Martin, F. C. & Umpleby, A. M., Aug 2008, In : Journal of Clinical Endocrinology and Metabolism. 93, 8, p. 3066-3074 9 p.

Research output: Contribution to journalArticle

35 Scopus citations
2007

Aging and diabetes: Mitochondrial dysfunction

Irving, B. A. & Sreekumaran Nair, K., Aug 1 2007, In : Current diabetes reports. 7, 4, p. 249-251 3 p.

Research output: Contribution to journalComment/debate

8 Scopus citations

A method for automatically interpreting mass spectra of 18O-labeled isotopic clusters

Mason, C. J., Therneau, T. M., Eckel-Passow, J. E., Johnson, K. L., Oberg, A. L., Olson, J. E., Nair, K. S., Muddiman, D. C. & Bergen, H. R., Feb 1 2007, In : Molecular and Cellular Proteomics. 6, 2, p. 305-318 14 p.

Research output: Contribution to journalArticle

52 Scopus citations

DHEA: Luftschloss statt jungbrunnen

Translated title of the contribution: DHEA: Castle in the air rather than the fountain of youthResch, K. L. & Nair, K. S., Jun 1 2007, In : Forschende Komplementarmedizin. 14, 3, p. 185-186 2 p.

Research output: Contribution to journalComment/debate

DHEA and testosterone are not effective in aging patients

Nair, K. S., Rizza, R. A. & O'Brien, P., Jan 1 2007, In : Cleveland Clinic journal of medicine. 74, 1, 1 p.

Research output: Contribution to journalArticle

Effect of 2 years of testosterone replacement on insulin secretion, insulin action, glucose effectiveness, hepatic insulin clearance, and postprandial glucose turnover in elderly men

Basu, R., Dalla Man, C., Campioni, M., Basu, A., Nair, K. S., Jensen, M. D., Khosla, S., Klee, G., Toffolo, G., Cobelli, C. & Rizza, R. A., Aug 1 2007, In : Diabetes care. 30, 8, p. 1972-1978 7 p.

Research output: Contribution to journalArticle

68 Scopus citations