• 20350 Citations
  • 79 Scopus h-Index
1974 …2020

Research output per year

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Research Output

2015

Effect of insulin sensitizer therapy on amino acids and their metabolites

Irving, B. A., Carter, R. E., Soop, M., Weymiller, A., Syed, H., Karakelides, H., Bhagra, S., Short, K. R., Tatpati, L., Barazzoni, R. & Nair, K. S., Jun 1 2015, In : Metabolism: Clinical and Experimental. 64, 6, p. 720-728 9 p.

Research output: Contribution to journalArticle

36 Scopus citations

Mitochondrial Aging and Physical Decline: Insights From Three Generations of Women

Hebert, S. L., Marquet-De Rougé, P., Lanza, I. R., McCrady-Spitzer, S. K., Levine, J. A., Middha, S., Carter, R. E., Klaus, K. A., Therneau, T. M., Highsmith, E. W. & Nair, K. S., Nov 2015, In : Journals of Gerontology - Series A Biological Sciences and Medical Sciences. 70, 11, p. 1409-1417 9 p.

Research output: Contribution to journalArticle

25 Scopus citations

Statement of principle

Cefalu, W. T., Nair, K. S., Seaquist, E. R., Zierath, J., Boulton, A. J. M., LeRoith, D., Harrell, R. M., Grunberger, G., Wartofsky, L., Gore, A. C., Wierman, M. E., Hammes, S. R., Lange, C. A. & Santen, R. J., Feb 1 2015, In : Hormones and Cancer. 6, 1, p. 1 1 p.

Research output: Contribution to journalArticle

2014

Adipocyte mitochondrial function is reduced in human obesity independent of fat cell size

Xiao, Y. X., Lanza, I. R., Swain, J. M., Sarr, M. G., Nair, K. S. & Jensen, M. D., Feb 1 2014, In : Journal of Clinical Endocrinology and Metabolism. 99, 2, p. E209-E216

Research output: Contribution to journalArticle

80 Scopus citations

Altered regulation of energy homeostasis in older rats in response to thyroid hormone administration

Walrand, S., Short, K. R., Heemstra, L. A., Novak, C. M., Levine, J. A., Coenen-Schimke, J. M. & Nair, K. S., Mar 2014, In : FASEB Journal. 28, 3, p. 1499-1510 12 p.

Research output: Contribution to journalArticle

9 Scopus citations
13 Scopus citations

Fasting increases human skeletal muscle net phenylalanine release and this is associated with decreased mTOR signaling

Vendelbo, M. H., Møller, A. B., Christensen, B., Nellemann, B., Clasen, B. F. F., Nair, K. S., Jørgensen, J. O. L., Jessen, N. & Møller, N., Jul 14 2014, In : PloS one. 9, 7, e102031.

Research output: Contribution to journalArticle

32 Scopus citations

G protein-coupled receptor 56 regulates mechanical overload-induced muscle hypertrophy

White, J. P., Wrann, C. D., Rao, R. R., Nair, S. K., Jedrychowski, M. P., You, J. S., Martínez-Redondo, V., Gygi, S. P., Ruas, J. L., Hornberger, T. A., Wu, Z., Glass, D. J., Piao, X. & Spiegelman, B. M., Nov 4 2014, In : Proceedings of the National Academy of Sciences of the United States of America. 111, 44, p. 15756-15761 6 p.

Research output: Contribution to journalArticle

44 Scopus citations

High insulin combined with essential amino acids stimulates skeletal muscle mitochondrial protein synthesis while decreasing insulin sensitivity in healthy humans

Robinson, M. M., Soop, M., Sohn, T. S., Morse, D. M., Schimke, J. M., Klaus, K. A. & Nair, K. S., Dec 1 2014, In : Journal of Clinical Endocrinology and Metabolism. 99, 12, p. E2574-E2583

Research output: Contribution to journalArticle

31 Scopus citations

Impact of insulin deprivation and treatment on sphingolipid distribution in different muscle subcellular compartments of streptozotocin-diabetic C57Bl/6 mice

Zabielski, P., Blachnio-Zabielska, A., Lanza, I. R., Gopala, S., Manjunatha, S., Jakaitis, D. R., Persson, X. M., Gransee, J., Klaus, K. A., Schimke, J. M., Jensen, M. D. & Nair, K. S., Jan 1 2014, In : American Journal of Physiology - Endocrinology and Metabolism. 306, 5, p. E529-E542

Research output: Contribution to journalArticle

15 Scopus citations

Induction of hyperandrogenism in lean reproductive-age women stimulates proatherogenic inflammation

González, F., Nair, K. S., Basal, E., Bearson, D. M., Schimke, J. M. & Blair, H. E., Sep 17 2014, In : Hormone and Metabolic Research. 47, 6, p. 439-444 6 p.

Research output: Contribution to journalArticle

9 Scopus citations

Leucine modulates dynamic phosphorylation events in insulin signaling pathway and enhances insulin-dependent glycogen synthesis in human skeletal muscle cells

Di Camillo, B., Eduati, F., Nair, S. K., Avogaro, A. & Toffolo, G. M., Mar 20 2014, In : BMC Cell Biology. 15, 1, 9.

Research output: Contribution to journalArticle

11 Scopus citations

Protein intake and exercise for optimal muscle function with aging: Recommendations from the ESPEN Expert Group

Deutz, N. E. P., Bauer, J. M., Barazzoni, R., Biolo, G., Boirie, Y., Bosy-Westphal, A., Cederholm, T., Cruz-Jentoft, A., Krznariç, Z., Nair, K. S., Singer, P., Teta, D., Tipton, K. & Calder, P. C., Dec 1 2014, In : Clinical Nutrition. 33, 6, p. 929-936 8 p.

Research output: Contribution to journalArticle

483 Scopus citations

Statement of principle

Cefalu, W. T., Nair, K. S., Seaquist, E. R., Zierath, J., Boulton, A. J. M., LeRoith, D., Harrell, R. M., Grunberger, G., Wartofsky, L., Gore, A. C., Wierman, M. E., Hammes, S. R., Lange, C. A. & Santen, R. J., Dec 1 2014, In : Journal of Clinical Endocrinology and Metabolism. 99, 12, 1 p.

Research output: Contribution to journalEditorial

1 Scopus citations

Statement of principle

Cefalu, W. T., Nair, K. S., Seaquist, E. R., Zierath, J., Boulton, A. J. M., LeRoith, D., Mack Harrell, R., Grunberger, G., Wartofsky, L., Gore, A. C., Wierman, M. E., Hammes, S. R., Lange, C. A. & Santen, R. J., 2014, In : Endocrine reviews. 35, 6, 1 p.

Research output: Contribution to journalEditorial

Time to look back and to look forward

Nair, K. S., Abel, E. D., Adler, S. G., Dyck, P. J., Gardner, T. W., Haskins, K. M., Hotamisligil, G., Jensen, M. D., Krook, A., Mandarino, L. J., Mitchell, B. D., Pessin, J. E., Sowers, J. R., Sussel, L., Wareham, N. & Vella, A., Apr 1 2014, In : Diabetes. 63, 4, p. 1169-1170 2 p.

Research output: Contribution to journalComment/debate

Upper-body obese women are resistant to postprandial stimulation of protein synthesis

Liebau, F., Jensen, M. D., Nair, K. S. & Rooyackers, O., Oct 2014, In : Clinical Nutrition. 33, 5, p. 802-807 6 p.

Research output: Contribution to journalArticle

5 Scopus citations
2013

Assessment of old and new proteins: A novel methodology

Johnson, M. L. & Nair, K. S., Jan 1 2013, In : Nutrition, Metabolism and Cardiovascular Diseases. 23, SUPPL1, p. S6-S11

Research output: Contribution to journalReview article

Comparison of different mass spectrometry techniques in the measurement of L-[ring-13C6]phenylalanine incorporation into mixed muscle proteins

Zabielski, P., Ford, G. C., Persson, X. M., Jaleel, A., Dewey, J. D. & Nair, K. S., Feb 1 2013, In : Journal of Mass Spectrometry. 48, 2, p. 269-275 7 p.

Research output: Contribution to journalArticle

14 Scopus citations

Cystathionine Beta-Synthase (CBS) Contributes to Advanced Ovarian Cancer Progression and Drug Resistance

Bhattacharyya, S., Saha, S., Giri, K., Lanza, I. R., Nair, K. S., Jennings, N. B., Rodriguez-Aguayo, C., Lopez-Berestein, G., Basal, E., Weaver, A. L., Visscher, D. W., Cliby, W., Sood, A. K., Bhattacharya, R. & Mukherjee, P., Nov 13 2013, In : PloS one. 8, 11, e79167.

Research output: Contribution to journalArticle

107 Scopus citations

Influence of fish oil on skeletal muscle mitochondrial energetics and lipid metabolites during high-fat diet.

Lanza, I. R., Blachnio-Zabielska, A., Johnson, M. L., Schimke, J. M., Jakaitis, D. R., Lebrasseur, N. K., Jensen, M. D., Sreekumaran Nair, K. & Zabielski, P., Jun 15 2013, In : American journal of physiology. Endocrinology and metabolism. 304, 12, p. E1391-1403

Research output: Contribution to journalArticle

63 Scopus citations

Mitochondrial and skeletal muscle health with advancing age

Konopka, A. R. & Sreekumaran Nair, K., Oct 15 2013, In : Molecular and Cellular Endocrinology. 379, 1-2, p. 19-29 11 p.

Research output: Contribution to journalArticle

27 Scopus citations

Skeletal muscle aging and the mitochondrion

Johnson, M. L., Robinson, M. M. & Nair, S. K., May 1 2013, In : Trends in Endocrinology and Metabolism. 24, 5, p. 247-256 10 p.

Research output: Contribution to journalReview article

106 Scopus citations

Sparing of muscle mass and function by passive loading in an experimental intensive care unit model

Renaud, G., Llano-Diez, M., Ravara, B., Gorza, L., Feng, H. Z., Jin, J. P., Cacciani, N., Gustafson, A. M., Ochala, J., Corpeno, R., Li, M., Hedström, Y., Ford, G. C., Nair, K. S. & Larsson, L., Mar 1 2013, In : Journal of Physiology. 591, 5, p. 1385-1402 18 p.

Research output: Contribution to journalArticle

26 Scopus citations

The 2010 ESPEN Sir David Cuthbertson Lecture: New and old proteins: Clinical implications

McCoy, R. G. & Nair, K. S., Oct 1 2013, In : Clinical Nutrition. 32, 5, p. 728-736 9 p.

Research output: Contribution to journalArticle

5 Scopus citations
2012

Acute free fatty acid elevation eliminates endurance training effect on insulin sensitivity

Chow, L. S., Seaquist, E. R., Eberly, L. E., Mashek, M. T., Schimke, J. M., Nair, K. S. & Mashek, D. G., Aug 1 2012, In : Journal of Clinical Endocrinology and Metabolism. 97, 8, p. 2890-2897 8 p.

Research output: Contribution to journalArticle

8 Scopus citations

Age effect on myocellular remodeling: Response to exercise and nutrition in humans

Irving, B. A., Robinson, M. M. & Nair, K. S., Jul 1 2012, In : Ageing Research Reviews. 11, 3, p. 374-389 16 p.

Research output: Contribution to journalReview article

13 Scopus citations

A PGC-1α isoform induced by resistance training regulates skeletal muscle hypertrophy

Ruas, J. L., White, J. P., Rao, R. R., Kleiner, S., Brannan, K. T., Harrison, B. C., Greene, N. P., Wu, J., Estall, J. L., Irving, B. A., Lanza, I. R., Rasbach, K. A., Okutsu, M., Nair, K. S., Yan, Z., Leinwand, L. A. & Spiegelman, B. M., Dec 7 2012, In : Cell. 151, 6, p. 1319-1331 13 p.

Research output: Contribution to journalArticle

348 Scopus citations

Changing of the guards

Nair, K. S., Jan 1 2012, In : Diabetes. 61, 1, p. 1-3 3 p.

Research output: Contribution to journalEditorial

Chronic caloric restriction preserves mitochondrial function in senescence without increasing mitochondrial biogenesis

Lanza, I. R., Zabielski, P., Klaus, K. A., Morse, D. M., Heppelmann, C. J., Bergen, H. R., Dasari, S., Walrand, S., Short, K. R., Johnson, M. L., Robinson, M. M., Schimke, J. M., Jakaitis, D. R., Asmann, Y. W., Sun, Z. & Nair, K. S., Dec 5 2012, In : Cell Metabolism. 16, 6, p. 777-788 12 p.

Research output: Contribution to journalArticle

108 Scopus citations

Coingestion of whey protein and casein in a mixed meal: Demonstration of a more sustained anabolic effect of casein

Soop, M., Nehra, V., Henderson, G. C., Boirie, Y., Ford, G. C. & Sreekumaran Nair, K., Jul 1 2012, In : American Journal of Physiology - Endocrinology and Metabolism. 303, 1, p. E152-E162

Research output: Contribution to journalArticle

27 Scopus citations

Concordance of changes in metabolic pathways based on plasma metabolomics and skeletal muscle transcriptomics in type 1 diabetes

Dutta, T., Chai, H. S., Ward, L. E., Ghosh, A., Persson, X. M. T., Ford, G. C., Kudva, Y. C., Sun, Z., Asmann, Y. W., Kocher, J. P. A. & Nair, K. S., May 1 2012, In : Diabetes. 61, 5, p. 1004-1016 13 p.

Research output: Contribution to journalArticle

42 Scopus citations

Effect of insulin sensitizer therapy on atherothrombotic and inflammatory profiles associated with insulin resistance

McCoy, R. G., Irving, B. A., Soop, M., Srinivasan, M., Tatpati, L., Chow, L., Weymiller, A. J., Carter, R. E. & Nair, K. S., Jun 2012, In : Mayo Clinic proceedings. 87, 6, p. 561-570 10 p.

Research output: Contribution to journalArticle

11 Scopus citations

Effects of type 2 diabetes and insulin on whole-body, splanchnic, and leg protein metabolism

Short, K. R., Irving, B. A., Basu, A., Johnson, C. M., Nair, K. S. & Basu, R., Dec 1 2012, In : Journal of Clinical Endocrinology and Metabolism. 97, 12, p. 4733-4741 9 p.

Research output: Contribution to journalArticle

4 Scopus citations

Electron spray ionization mass spectrometry and 2D 31P NMR for monitoring 18O/16O isotope exchange and turnover rates of metabolic oligophosphates

Nemutlu, E., Juranic, N., Zhang, S., Ward, L. E., Dutta, T., Sreekumaran Nair, K., Terzic, A., Macura, S. & Dzeja, P. P., May 1 2012, In : Analytical and bioanalytical chemistry. 403, 3, p. 697-706 10 p.

Research output: Contribution to journalArticle

8 Scopus citations

Endurance exercise as a countermeasure for aging (Diabetes (2008) 57, (2933-2942))

Lanza, I. R., Short, D. K., Short, K. R., Raghavakaimal, S., Basu, R., Joyner, M. J., McConnell, J. P. & Nair, K. S., Oct 1 2012, In : Diabetes. 61, 10, 1 p.

Research output: Contribution to journalComment/debate

1 Scopus citations

Function-based discovery of significant transcriptional temporal patterns in insulin stimulated muscle cells

Di Camillo, B., Irving, B. A., Schimke, J., Sanavia, T., Toffolo, G., Cobelli, C. & Nair, K. S., Mar 1 2012, In : PloS one. 7, 3, e32391.

Research output: Contribution to journalArticle

8 Scopus citations

Hormone replacement therapy and physical function in healthy older men. Time to talk hormones?

Giannoulis, M. G., Martin, F. C., Nair, K. S., Umpleby, A. M. & Sonksen, P., Jun 2012, In : Endocrine reviews. 33, 3, p. 314-377 64 p.

Research output: Contribution to journalReview article

69 Scopus citations

Hyperandrogenism sensitizes leukocytes to hyperglycemia to promote oxidative stress in lean reproductive-age women

González, F., Nair, K. S., Daniels, J. K., Basal, E., Schimke, J. M. & Blair, H. E., Aug 1 2012, In : Journal of Clinical Endocrinology and Metabolism. 97, 8, p. 2836-2843 8 p.

Research output: Contribution to journalArticle

44 Scopus citations

Hyperandrogenism sensitizes mononuclear cells to promote glucose-induced inflammation in lean reproductive-age women

González, F., Sreekumaran Nair, K., Daniels, J. K., Basal, E. & Schimke, J. M., Feb 1 2012, In : American Journal of Physiology - Endocrinology and Metabolism. 302, 3, p. 297-306 10 p.

Research output: Contribution to journalArticle

39 Scopus citations

Insulin fails to enhance mTOR phosphorylation, mitochondrial protein synthesis, and ATP production in human skeletal muscle without amino acid replacement

Barazzoni, R., Short, K. R., Asmann, Y., Coenen-Schimke, J. M., Robinson, M. M. & Nair, K. S., Nov 1 2012, In : American Journal of Physiology - Endocrinology and Metabolism. 303, 9, p. E1117-E1125

Research output: Contribution to journalArticle

30 Scopus citations

Insulin-mediated FFA suppression is associated with triglyceridemia and insulin sensitivity independent of adiposity

Bush, N. C., Basu, R., Rizza, R. A., Nair, K. S., Khosla, S. & Jensen, M. D., Nov 1 2012, In : Journal of Clinical Endocrinology and Metabolism. 97, 11, p. 4130-4138 9 p.

Research output: Contribution to journalArticle

12 Scopus citations
2011

Alterations in protein metabolism in diabetes mellitus

Stump, C. S. & Nair, K. S., Nov 3 2011, Joslin's Diabetes Mellitus: Fourteenth Edition. Wolters Kluwer Health Adis (ESP), p. 275-290 16 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

1 Scopus citations

Can dietary nitrates enhance the efficiency of mitochondria?

Nair, K. S., Irving, B. A. & Lanza, I. R., Feb 2 2011, In : Cell Metabolism. 13, 2, p. 117-118 2 p.

Research output: Contribution to journalShort survey

4 Scopus citations
9 Scopus citations

Influence of frailty and health status on outcomes in patients with coronary disease undergoing percutaneous revascularization

Singh, M., Rihal, C. S., Lennon, R. J., Spertus, J. A., Nair, K. S. & Roger, V. L., Sep 1 2011, In : Circulation: Cardiovascular Quality and Outcomes. 4, 5, p. 496-502 7 p.

Research output: Contribution to journalArticle

142 Scopus citations
60 Scopus citations

Mitochondrial longevity pathways

Vendelbo, M. H. & Nair, K. S., Apr 1 2011, In : Biochimica et Biophysica Acta - Molecular Cell Research. 1813, 4, p. 634-644 11 p.

Research output: Contribution to journalReview article

56 Scopus citations
29 Scopus citations